Acute Myeloid Leukemia (AML) is a cancer of myeloid lineage cells in blood. Here, we’re collecting a list of papers, reviews, and possibly applications related to AML.
| Manuscript | Link |
|---|---|
| Not Only Mutations Matter: Molecular Picture of Acute Myeloid Leukemia Emerging from Transcriptome Studies | Journal of Oncology, 2019 |
| Single-Cell RNA Sequencing to Disentangle the Blood System | Arteriosclerosis, Thrombosis, and Vascular Biology, 2021 |
| Hematopoietic Stem Cell: Self-renewal versus Differentiation | Wiley Interdiscip Rev Syst Biol Med., 2010 |
| Manuscript | Link |
|---|---|
| The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/ Dendritic Neoplasms | Leukemia, 2022 |
| World Health Organization classification of myeloid neoplasms and acute leukemia | Blood, 2016 |
| Genomic Classification and Prognosis in Acute Myeloid Leukemia | N Engl J Med, 2016 |
| Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood, 2017 |
| Validation and refinement of the revised 2017 European Leukemia Net genetic risk stratification of acute myeloid leukemia | Leukemia, 2020 |
| Manuscript | Link |
|---|---|
| Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses | Leukemia, 2024 |
| A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML | NPJ PO, 2024 |
| A 17-gene stemness score for rapid determination of risk in acute leukaemia | Nature, 2016 |
| A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia | Nature Comm., 2021 |
| A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia | Nat Med., 2022 |
| Functional genomic landscape of acute myeloid leukaemia (BEAT-AML) | Nature, 2018 |
| Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia | Cancer Disc., 2020 |
| Manuscript | Link |
|---|---|
| Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity | Cell, 2019 |
| A single-cell survey of cellular hierarchy in acute myeloid leukemia | Journal of Hematology & Oncology, 2020 |
| Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression | Leukemia, 2021 |
| A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing | Nature Comm., 2019 |
| Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics | iScience, 2020 |
| Manuscript | Link |
|---|---|
| Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia | Cell Stem Cell, 2023 |
| Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states | Nat Immun., 2021 |
| Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics | Nature Comm., 2021 |
| Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia* | Nature Biotech., 2019 |
| Manuscript | Link |
|---|---|
| Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution* | Nature Gen., 2016 |
| Manuscript | Link |
|---|---|
| EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes | Leukemia, 2012 |
| Manuscript | Link |
|---|---|
| Single-cell mutation analysis of clonal evolution in myeloid malignancies* | Nature, 2020 |
| The Origin and Evolution of Mutations in Acute Myeloid Leukemia | Cell, 2012 |
| Manuscript | Link |
|---|---|
| Biological and therapeutic implications of a unique subtype of NPM1 mutated AML | Nature Comm., 2021 |
* might not be exactly AML but leukemia
PRs are more than welcome and encouraged!
Note: I am mostly interested in transcriptional and epigenetic changes in AML at single-cell scale, thus making the repo biased towards related papers.
- Fork this repository
- Make a change to README.md
- Submit a pull request.