Acute Myeloid
Leukemia
(AML ) is a cancer of myeloid lineage cells in blood. Here, we’re
collecting a list of papers, reviews, and possibly applications related
to AML.
Manuscript
Link
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/ Dendritic Neoplasms
Leukemia, 2022
World Health Organization classification of myeloid neoplasms and acute leukemia
Blood, 2016
Genomic Classification and Prognosis in Acute Myeloid Leukemia
N Engl J Med, 2016
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
Blood, 2017
Validation and refinement of the revised 2017 European Leukemia Net genetic risk stratification of acute myeloid leukemia
Leukemia, 2020
Manuscript
Link
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses
Leukemia, 2024
A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML
NPJ PO, 2024
A 17-gene stemness score for rapid determination of risk in acute leukaemia
Nature, 2016
A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia
Nature Comm., 2021
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
Nat Med., 2022
Functional genomic landscape of acute myeloid leukaemia (BEAT-AML )
Nature, 2018
Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia
Cancer Disc., 2020
Single-cell Transcriptomics
Manuscript
Link
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
Cell, 2019
A single-cell survey of cellular hierarchy in acute myeloid leukemia
Journal of Hematology & Oncology, 2020
Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression
Leukemia, 2021
A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing
Nature Comm., 2019
Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics
iScience, 2020
Manuscript
Link
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia
Cell Stem Cell, 2023
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
Nat Immun., 2021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
Nature Comm., 2021
Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia*
Nature Biotech., 2019
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Link
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution*
Nature Gen., 2016
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Link
EuroFlow antibody panels for standardized n -dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes
Leukemia, 2012
Manuscript
Link
Single-cell mutation analysis of clonal evolution in myeloid malignancies*
Nature, 2020
The Origin and Evolution of Mutations in Acute Myeloid Leukemia
Cell, 2012
Manuscript
Link
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML
Nature Comm., 2021
* might not be exactly AML but leukemia
PRs are more than welcome and encouraged!
Note: I am mostly interested in transcriptional and epigenetic changes
in AML at single-cell scale, thus making the repo biased towards
related papers.
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