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Script to calculate polygenic risk scores in a genotyped sample using GWAS summary statistics from a disease/trait.

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pgormley/polygenic-risk-scores

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polygenic-risk-scores


Author

Padhraig Gormley

Massachusetts General Hospital | Broad Institute of MIT and Harvard.


Synopsis

Script for calculating polygenic risk scores in a genotyped sample using GWAS summary statistics from a disease/trait.


Dependencies

PLINK (https://www.cog-genomics.org/plink2)


Usage

Open your bash or other shell. Then to run the script with the supplied toy data type:

./calc-PRS-scores.sh myStudyName imputedSampleRootName GWASresultsFile

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Script to calculate polygenic risk scores in a genotyped sample using GWAS summary statistics from a disease/trait.

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