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Analysis of public and unpublished scRNA-seq data from bone marrow donors

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Bone marrow analysis

This repository contains code and data needed to reproduce the analysis from this paper: Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia. Ennis S et. al., iScience, 2023. DOI: 10.1016/j.isci.2023.106943.

The raw scRNA-seq data that was generated as part of this study is available on GEO (GSE227903) and the integrated scRNA-seq atlas of the bone marrow in health and AML is available on zenodo.

To explore the integrated dataset, this repository contains a Google Colab notebook (bone_marrow_atlas.ipynb) that contains code to generate an interactive cellxgene session.

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Analysis of public and unpublished scRNA-seq data from bone marrow donors

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