SBML.jl

Build status	Documentation

This is a simple wrap of some of the libSBML functionality, mainly the model loading for purposes of COBRA analysis methods and exploration of ODE system and reaction dynamics.

You might like to try the packages that use SBML.jl; these now include:

• COBREXA.jl, the exascale-ready constraint-based analysis and reconstruction toolkit for finding and modeling steady metabolic fluxes with the models
• Connections to the SciML ModelingToolkit ecosystem:
  • SBMLToolkit.jl, for working with the models' reaction dynamics as ODE systems.
  • SBMLImporter.jl for importing the SBML models into Catalyst.jl, allowing simulations via Catalyst's JumpProblem, SDEProblem, or ODEProblem and fitting models to data via PEtab.jl.

Other functionality will be added as needed. Feel free to submit a PR that increases the loading "coverage".

Acknowledgements

SBML.jl was developed at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg (lcsb.uni.lu), and the UCL Research Software Development Group (ucl.ac.uk/arc). The development was supported by European Union's Horizon 2020 Programme under PerMedCoE project (permedcoe.eu) agreement no. 951773, and Chan Zuckerberg Initiative (chanzuckerberg.com) under grant 2020-218578 (5022).

         

Installation

]add SBML # or
using Pkg; Pkg.add("SBML")

Usage

using SBML
m = readSBML("myModel.xml")

# m is now a Model structure with:
m.reactions
m.species
m.compartments
...

There are several helper functions, for example you can get a nice list of reactions, metabolites and the stoichiometric matrix as follows:

mets, rxns, S = stoichiometry_matrix(m)