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DESCRIPTION
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DESCRIPTION
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Package: IgGeneUsage
Type: Package
Title: Differential gene usage in immune repertoires
Version: 1.17.27
Authors@R:
person(given = "Simo",
family = "Kitanovski",
role = c("aut", "cre"),
email = "simo.kitanovski@uni-due.de")
Description: Detection of biases in the usage of immunoglobulin (Ig) genes
is an important task in immune repertoire profiling. IgGeneUsage detects
aberrant Ig gene usage between biological conditions using a probabilistic
model which is analyzed computationally by Bayes inference. With this
IgGeneUsage also avoids some common problems related to the current
practice of null-hypothesis significance testing.
License: MIT + file LICENSE
Depends:
R (>= 4.2.0)
Imports:
methods,
reshape2 (>= 1.4.3),
Rcpp (>= 0.12.0),
RcppParallel (>= 5.0.1),
rstan (>= 2.18.1),
rstantools (>= 2.2.0),
SummarizedExperiment,
tidyr
Suggests:
BiocStyle,
knitr,
rmarkdown,
testthat (>= 2.1.0),
ggplot2,
ggforce,
ggrepel,
patchwork
LinkingTo:
BH (>= 1.66.0),
Rcpp (>= 0.12.0),
RcppEigen (>= 0.3.3.3.0),
RcppParallel (>= 5.0.1),
rstan (>= 2.18.1),
StanHeaders (>= 2.18.0)
SystemRequirements: GNU make
Encoding: UTF-8
LazyData: false
NeedsCompilation: yes
biocViews: DifferentialExpression, Regression, Genetics, Bayesian,
BiomedicalInformatics, ImmunoOncology, MathematicalBiology
BugReports: https://github.com/snaketron/IgGeneUsage/issues
URL: https://github.com/snaketron/IgGeneUsage
RoxygenNote: 6.1.1
VignetteBuilder: knitr
Biarch: true