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DESCRIPTION
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DESCRIPTION
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Package: derfinder
Type: Package
Title: Annotation-agnostic differential expression analysis of RNA-seq data at
base-pair resolution via the DER Finder approach
Version: 1.39.0
Date: 2021-09-14
Authors@R: c(person("Leonardo", "Collado-Torres", role = c("aut", "cre"), email
= "lcolladotor@gmail.com", comment = c(ORCID = "0000-0003-2140-308X")),
person(c("Alyssa", "C."), "Frazee", role = c("ctb"),
email = "alyssa.frazee@gmail.com"), person(c("Andrew", "E."), "Jaffe",
role = "aut", email = "andrew.jaffe@libd.org",
comment = c(ORCID = "0000-0001-6886-1454")), person(c("Jeffrey", "T."),
"Leek", role = c("aut", "ths"), email = "jtleek@gmail.com",
comment = c(ORCID = "0000-0002-2873-2671")))
Depends:
R (>= 3.5.0)
Imports:
BiocGenerics (>= 0.25.1),
AnnotationDbi (>= 1.27.9),
BiocParallel (>= 1.15.15),
bumphunter (>= 1.9.2),
derfinderHelper (>= 1.1.0),
GenomeInfoDb (>= 1.3.3),
GenomicAlignments,
GenomicFeatures,
GenomicFiles,
GenomicRanges (>= 1.17.40),
Hmisc,
IRanges (>= 2.3.23),
methods,
qvalue (>= 1.99.0),
Rsamtools (>= 1.25.0),
rtracklayer,
S4Vectors (>= 0.23.19),
stats,
utils
Suggests:
BiocStyle (>= 2.5.19),
sessioninfo,
derfinderData (>= 0.99.0),
derfinderPlot,
DESeq2,
ggplot2,
knitr (>= 1.6),
limma,
RefManageR,
rmarkdown (>= 0.3.3),
testthat (>= 2.1.0),
TxDb.Hsapiens.UCSC.hg19.knownGene,
covr
VignetteBuilder: knitr
Description: This package provides functions for annotation-agnostic
differential expression analysis of RNA-seq data. Two implementations of
the DER Finder approach are included in this package: (1) single base-level
F-statistics and (2) DER identification at the expressed regions-level.
The DER Finder approach can also be used to identify differentially bounded
ChIP-seq peaks.
License: Artistic-2.0
LazyData: true
URL: https://github.com/lcolladotor/derfinder
BugReports: https://support.bioconductor.org/t/derfinder/
biocViews: DifferentialExpression, Sequencing, RNASeq, ChIPSeq,
DifferentialPeakCalling, Software, ImmunoOncology, Coverage
RoxygenNote: 7.2.3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)