README.Rmd

---
output: github_document
---

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knitr::opts_chunk$set(
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  fig.path = "man/figures/README-",
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)
```

# OneArmPhaseTwoStudy

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The Purpose of this package is it to plan, monitor and evaluate
oncological phase II studies. In general this kind of studies are single-arm
trials with planned interim analysis and binary endpoint. To meet the resulting
requirements, the package provides functions to calculate and evaluate 'Simon's
two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with
this package a good starting point is to take a closer look at the functions

```r
getSolutions()
```

and

```r
getSolutionsSub1()
```

The web-based tool (<https://imbi.shinyapps.io/phaseII-app/>)
extends the functionality of our R package by means of a proper dealing with over- and underrunning.
The R function binom.test of the 'stats' R package and the package 'binom' might be 
helpful to assess the performance of the corresponding one-stage design as a reference.