diff --git a/setup.cfg b/setup.cfg
index e9891ca..050a835 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -67,10 +67,10 @@ copy = vendor/hmmer/libdivsufsort/divsufsort.h.in
 [configure.easel]
 filename = esl_config.h
 constants =
-    EASEL_DATE      = "Nov 2020"
-    EASEL_COPYRIGHT = "Copyright (C) 2020 Howard Hughes Medical Institute"
+    EASEL_DATE      = "Aug 2023"
+    EASEL_COPYRIGHT = "Copyright (C) 2023 Howard Hughes Medical Institute"
     EASEL_LICENSE   = "Freely distributed under the BSD open source license."
-    EASEL_VERSION   = "0.48"
+    EASEL_VERSION   = "0.49"
     EASEL_URL       = "http://bioeasel.org/"
 headers =
     stdio.h
@@ -103,11 +103,11 @@ functions =
 [configure.hmmer]
 filename = p7_config.h
 constants =
-    HMMER_VERSION     = "3.3.2"
-    HMMER_DATE        = "Nov 2020"
+    HMMER_VERSION     = "3.4"
+    HMMER_DATE        = "Aug 2023"
     HMMER_LICENSE     = "Freely distributed under the BSD open source license."
     HMMER_URL         = "http://hmmer.org/"
-    HMMER_COPYRIGHT   = "Copyright (C) 2020 Howard Hughes Medical Institute."
+    HMMER_COPYRIGHT   = "Copyright (C) 2023 Howard Hughes Medical Institute."
     p7_RAMLIMIT       = 32
     p7_NCPU           = "2"
     p7_ALILENGTH      = 50