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STAR 2.7.7a --- 2020/12/28 ::: STARconsensus

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@alexdobin alexdobin released this 28 Dec 20:43
· 233 commits to master since this release

Major new feature: STARconsensus: mapping RNA-seq reads to consensus genome.

  • Insert (consensus) variants from a VCF file into the reference genome at the genome generation step with --genomeTransformVCF Variants.vcf --genomeTransformType Haploid
  • Map to the transformed genome. Alignments (SAM/BAM) and spliced junctions (SJ.out.tab) can be transformed back to the original (reference) coordinates with --genomeTransformOutput SAM and/or SJ
  • More information: https://github.com/alexdobin/STAR/tree/master/docs/STARconsensus.md

Minor bug fixes:

  • Deprecated --genomeConsensusFile option. Please use --genomeTransformVCF and --genomeTransformType options instead.
  • Issue #1040: fixed a bug causing rare seg-faults for paired-end --soloType SmartSeq runs.
  • Issue #1071: fixed a bug that can cause a crash for STARsolo runs with a small number of cells.