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It introduces STARconsensus, which allows mapping RNA-seq to the consensus genome, which is built by inserting major alleles into the reference genome.
Benjamin Kaminow @kaminow led the efforts to assess the increase of mapping accuracy with consensus genomes.
For more details, please check out bioRxiv preprint: https://www.biorxiv.org/content/10.1101/2020.12.22.423111v1
Benjamin also developed a separate tool for constructing consensus VCF from public databases: https://github.com/kaminow/ConsDB
As always, questions, comments, and suggestions are very welcome!
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Dear STAR Users,
STAR 2.7.7a has been released:
https://github.com/alexdobin/STAR/releases/tag/2.7.7a
It introduces STARconsensus, which allows mapping RNA-seq to the consensus genome, which is built by inserting major alleles into the reference genome.
Benjamin Kaminow @kaminow led the efforts to assess the increase of mapping accuracy with consensus genomes.
For more details, please check out bioRxiv preprint:
https://www.biorxiv.org/content/10.1101/2020.12.22.423111v1
Benjamin also developed a separate tool for constructing consensus VCF from public databases:
https://github.com/kaminow/ConsDB
As always, questions, comments, and suggestions are very welcome!
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