Covid19-Breakthrough

• main.R main entrance of the analysis;
• cohortCharacterizationAndRefine.R perform three steps
  • cohortDefinition.R defines vax, pre-vax, and un-vax cohorts
  • featureExtraction.R extracts relevant features for analysis
  • cohortCharacterizationAndRefine.R refines cohorts and provides cohorts characteristics (i.e. Table 1)
  • conceptDiagnosis.R identifies potential over-represented concepts in the COVID analysis - avoid systematic bias.
• BreakthroughFactorsAnalysis.R identifies risk factors associated with breakthrough infections
• covidPositiveComparison.R assessed the vaccine effectiveness in protection infection among different subgroups
• severeOutcomeComparison.R assessed the vaccine effectiveness in protecting from severe outcomes
• longitAnalysis.R reveals how vaccine changes long the time