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pubmedtext.txt
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PMID- 20719444
OWN - NLM
STAT- MEDLINE
DA - 20111010
DCOM- 20120518
LR - 20161125
IS - 1872-7727 (Electronic)
IS - 0720-048X (Linking)
VI - 80
IP - 2
DP - 2011 Nov
TI - Value of multislice computed tomography in the diagnosis of acute mesenteric
ischemia.
PG - 297-302
LID - 10.1016/j.ejrad.2010.07.016 [doi]
AB - OBJECTIVE: To define the value of multislice computed tomography (CT) in the
diagnosis of acute mesenteric ischemia (AMI). MATERIALS AND METHODS: Two hundred
patients (age range: 20-92 years) who were referred to the emergency CT
department with a clinical suspicion of AMI were prospectively included in the
study. CT examinations were performed with a multislice (16) CT scanner and the
protocol included pre-contrast, arterial and venous phase acquisitions. Images
were evaluated by using multiplanar reconstruction, maximum intensity projection
and volume-rendering techniques at the CT workstation. RESULTS: Ninety-four
patients (47%) underwent surgery for AMI or for other causes of acute abdominal
pain. One hundred-six patients (53%) were followed conservatively according to
clinical, radiologic and laboratory findings. Of the 94 patients who underwent
surgery, 49 (25%) were found to have AMI. All of these 49 patients with a proven
AMI diagnosis were diagnosed with CT. In the other 45 patients who underwent
surgery, CT findings were negative for AMI. None of the patients, who were
followed conservatively, were eventually diagnosed as having AMI except 1
patient. This patient was unfit for surgery although his clinical and radiologic
findings were consistent with AMI and died in 3 days. The sensitivity and
specificity values of CT for the detection of AMI were calculated to be 100% for
each. CONCLUSIONS: Multislice CT is an effective imaging technique for the
diagnosis of AMI with excellent sensitivity and specificity values.
CI - Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
FAU - Yikilmaz, Ali
AU - Yikilmaz A
AD - Erciyes University, School of Medicine, Gevher Nesibe Hospital, Department of
Radiology, Talas Yolu, 38038 Melikgazi, Kayseri, Turkey. dryikilmaz@yahoo.com
FAU - Karahan, Okkes Ibrahim
AU - Karahan OI
FAU - Senol, Serkan
AU - Senol S
FAU - Tuna, Ibrahim Sacit
AU - Tuna IS
FAU - Akyildiz, Hizir Yakup
AU - Akyildiz HY
LA - eng
PT - Journal Article
DEP - 20100816
PL - Ireland
TA - Eur J Radiol
JT - European journal of radiology
JID - 8106411
RN - 0 (Contrast Media)
SB - IM
MH - Abdomen, Acute/*diagnostic imaging/pathology
MH - Adult
MH - Aged
MH - Aged, 80 and over
MH - Angiography
MH - Chi-Square Distribution
MH - Contrast Media
MH - Diagnosis, Differential
MH - Female
MH - Humans
MH - Ischemia/*diagnostic imaging/pathology
MH - Male
MH - Mesenteric Ischemia
MH - Middle Aged
MH - Multidetector Computed Tomography/*methods
MH - Prospective Studies
MH - Sensitivity and Specificity
MH - Vascular Diseases/*diagnostic imaging/pathology
EDAT- 2010/08/20 06:00
MHDA- 2012/05/19 06:00
CRDT- 2010/08/20 06:00
PHST- 2010/05/03 [received]
PHST- 2010/07/15 [revised]
PHST- 2010/07/19 [accepted]
AID - S0720-048X(10)00353-0 [pii]
AID - 10.1016/j.ejrad.2010.07.016 [doi]
PST - ppublish
SO - Eur J Radiol. 2011 Nov;80(2):297-302. doi: 10.1016/j.ejrad.2010.07.016. Epub 2010
Aug 16.
PMID- 21748388
OWN - NLM
STAT- MEDLINE
DA - 20111003
DCOM- 20120123
LR - 20111003
IS - 1432-1084 (Electronic)
IS - 0938-7994 (Linking)
VI - 21
IP - 11
DP - 2011 Nov
TI - Quantitative in vivo MRI evaluation of lumbar facet joints and intervertebral
discs using axial T2 mapping.
PG - 2388-95
LID - 10.1007/s00330-011-2198-z [doi]
AB - OBJECTIVES: To assess the feasibility of T2 mapping of lumbar facet joints and
intervertebral discs in a single imaging slab and to compare the findings with
morphological grading. METHODS: Sixty lumbar spine segments from 10 low back pain
patients and 5 healthy volunteers were examined by axial T2 mapping and
morphological MRI at 3.0 Tesla. Regions of interest were drawn on a single slice
for the facet joints and the intervertebral discs (nucleus pulposus, anterior and
posterior annulus fibrosus). The Weishaupt grading was used for facet joints and
the Pfirrmann score was used for morphological disc grading ("normal" vs.
"abnormal" discs). RESULTS: The inter-rater agreement was excellent for the facet
joint T2 evaluation (r = 0.85), but poor for the morphological Weishaupt grading
(kappa = 0.15). The preliminary results show similar facet joint T2 values in
segments with normal and abnormal Pfirrmann scores. There was no difference in
mean T2 values between facet joints in different Weishaupt grading groups. Facet
joint T2 values showed a weak correlation with T2 values of the posterior annulus
(r = 0.32) CONCLUSIONS: This study demonstrates the feasibility of a combined T2
mapping approach for the facet joints and intervertebral discs using a single
axial slab.
FAU - Stelzeneder, David
AU - Stelzeneder D
AD - Department of Radiology, MR Centre-High field MR, Medical University of Vienna,
Lazarettgasse 14, 1090 Vienna, Austria. david.stelzeneder@meduniwien.ac.at
FAU - Messner, Alina
AU - Messner A
FAU - Vlychou, Marianna
AU - Vlychou M
FAU - Welsch, Goetz H
AU - Welsch GH
FAU - Scheurecker, Georg
AU - Scheurecker G
FAU - Goed, Sabine
AU - Goed S
FAU - Pieber, Karin
AU - Pieber K
FAU - Pflueger, Verena
AU - Pflueger V
FAU - Friedrich, Klaus M
AU - Friedrich KM
FAU - Trattnig, Siegfried
AU - Trattnig S
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20110712
PL - Germany
TA - Eur Radiol
JT - European radiology
JID - 9114774
SB - IM
MH - Adult
MH - Female
MH - Humans
MH - Image Processing, Computer-Assisted
MH - Intervertebral Disc/*pathology
MH - Low Back Pain/*pathology
MH - Lumbar Vertebrae/*pathology
MH - Magnetic Resonance Imaging/*methods
MH - Male
MH - Middle Aged
MH - Observer Variation
MH - Reproducibility of Results
MH - Zygapophyseal Joint/*pathology
EDAT- 2011/07/13 06:00
MHDA- 2012/01/24 06:00
CRDT- 2011/07/13 06:00
PHST- 2011/03/29 [received]
PHST- 2011/05/26 [accepted]
PHST- 2011/05/16 [revised]
AID - 10.1007/s00330-011-2198-z [doi]
PST - ppublish
SO - Eur Radiol. 2011 Nov;21(11):2388-95. doi: 10.1007/s00330-011-2198-z. Epub 2011
Jul 12.
PMID- 22195370
OWN - NLM
STAT- MEDLINE
DA - 20111226
DCOM- 20120117
LR - 20111226
IS - 1128-3602 (Print)
IS - 1128-3602 (Linking)
VI - 15
IP - 11
DP - 2011 Nov
TI - Intraosseous lipoma presenting as a sphenoid sinus mass.
PG - 1339-42
AB - Intraosseous lipoma is an uncommon mesenchymal tumor that is frequently found in
appendecular skeleton. In extremely rare conditions, it can appear in sphenoid
bone, and only 2 cases have been described in literature until now. We present a
case of lipoma in the body of the sphenoid bone mimicking sphenoid sinus tumor. A
16-year-old man presented to Department of Otorhinolaryngology with a complaint
of nonspecific headache. There were any clinical findings on physical
examination. Computed tomography (CT) and magnetic resonance imaging (MRI)
revealed and the diagnosis was made on these imaging findings. Other diagnostic
technique, invasive histopathological assessment was not necessary. To our
knowledge, this is the first case of lipoma in the body of the sphenoid bone with
indentation to sphenoid sinus. The patient has been followed-up radiologically
without the need for surgery for two years.
FAU - Dogan, M
AU - Dogan M
AD - Department of Radiology, Inonu University School of Medicine, Malatya, Turkey.
metindogantr@gmail.com
FAU - Kahraman, A S
AU - Kahraman AS
FAU - Firat, C
AU - Firat C
FAU - Kahraman, B
AU - Kahraman B
FAU - Karatas, E
AU - Karatas E
FAU - Kizilay, A
AU - Kizilay A
LA - eng
PT - Case Reports
PT - Journal Article
PL - Italy
TA - Eur Rev Med Pharmacol Sci
JT - European review for medical and pharmacological sciences
JID - 9717360
SB - IM
MH - Adolescent
MH - Bone Neoplasms/complications/*diagnosis
MH - Headache/etiology
MH - Humans
MH - Lipoma/complications/*diagnosis/pathology
MH - Magnetic Resonance Imaging
MH - Male
MH - Skull Neoplasms/complications/*diagnosis/pathology
MH - Sphenoid Bone/*pathology
MH - Sphenoid Sinus/*pathology
MH - Tomography, X-Ray Computed
MH - Watchful Waiting
EDAT- 2011/12/27 06:00
MHDA- 2012/01/18 06:00
CRDT- 2011/12/27 06:00
PST - ppublish
SO - Eur Rev Med Pharmacol Sci. 2011 Nov;15(11):1339-42.
PMID- 22195362
OWN - NLM
STAT- MEDLINE
DA - 20111226
DCOM- 20120117
LR - 20151119
IS - 1128-3602 (Print)
IS - 1128-3602 (Linking)
VI - 15
IP - 11
DP - 2011 Nov
TI - Combined occlusal and pharmacological therapy in the treatment of
temporo-mandibular disorders.
PG - 1296-300
AB - OBJECTIVE: Aim of the present work is to assess the effectiveness of a scientific
protocol built up to relieve pain in chronic temporo-mandibular disorders (TMD)
using Michigan splint together with a pharmacological therapy compared to the
traditional occlusal therapy by Michigan splint alone. PATIENTS: 35 adult
patients, with signs and symptoms of TMD lasting more than 6 months, were
enrolled into this study and divided into two groups: the first receiving
occlusal therapy by Michigan splint and pharmacological therapy with Delorazepam
and Thiocolchicoside, while the second receiving occlusal therapy by Michigan
splint and "placebo" administration. The comparisons between the two experimental
groups were assessed using a 5 steps visual-analogue scale (V.A.S.). RESULTS AND
CONCLUSIONS: The outcomes from the experimental groups were statistically
compared resulting significantly different with an improvement or disappearance
of signs and symptoms in the treated group with respect to the placebo group at
12 and 18 months from the beginning of the experiment (p < 0.001).
FAU - Inchingolo, F
AU - Inchingolo F
AD - Department of Biomedical Sciences and Human Oncology, Toxicology Unit, University
of Bari, Bari, Italy.
FAU - Tatullo, M
AU - Tatullo M
FAU - Marrelli, M
AU - Marrelli M
FAU - Inchingolo, A M
AU - Inchingolo AM
FAU - Tarullo, A
AU - Tarullo A
FAU - Inchingolo, A D
AU - Inchingolo AD
FAU - Dipalma, G
AU - Dipalma G
FAU - Podo Brunetti, S
AU - Podo Brunetti S
FAU - Tarullo, A
AU - Tarullo A
FAU - Cagiano, R
AU - Cagiano R
LA - eng
PT - Journal Article
PL - Italy
TA - Eur Rev Med Pharmacol Sci
JT - European review for medical and pharmacological sciences
JID - 9717360
RN - 0 (Muscle Relaxants, Central)
RN - 12794-10-4 (Benzodiazepines)
RN - 67220MCM01 (Nordazepam)
RN - O91W32476G (chlordesmethyldiazepam)
RN - SML2Y3J35T (Colchicine)
RN - T1X8S697GT (thiocolchicoside)
SB - IM
MH - Adult
MH - Benzodiazepines/therapeutic use
MH - Chronic Disease
MH - Colchicine/analogs & derivatives/therapeutic use
MH - Combined Modality Therapy
MH - Female
MH - Humans
MH - Male
MH - Middle Aged
MH - Muscle Relaxants, Central/therapeutic use
MH - Nordazepam/analogs & derivatives/therapeutic use
MH - *Occlusal Splints
MH - Pain/drug therapy/etiology
MH - Pain Measurement/drug effects
MH - Temporomandibular Joint Disorders/*drug therapy/*therapy
MH - Treatment Outcome
EDAT- 2011/12/27 06:00
MHDA- 2012/01/18 06:00
CRDT- 2011/12/27 06:00
PST - ppublish
SO - Eur Rev Med Pharmacol Sci. 2011 Nov;15(11):1296-300.
PMID- 21706361
OWN - NLM
STAT- MEDLINE
DA - 20111028
DCOM- 20120719
LR - 20170220
IS - 1432-0932 (Electronic)
IS - 0940-6719 (Linking)
VI - 20
IP - 11
DP - 2011 Nov
TI - Surgery improves pain, function and quality of life in patients with spinal
metastases: a prospective study on 118 patients.
PG - 1970-8
LID - 10.1007/s00586-011-1867-6 [doi]
AB - PURPOSE: There are few prospective studies on surgical outcomes and survival in
patients with metastatic disease to the spine. The magnitude and duration of
effect of surgery on pain relief and quality of life remains uncertain.
Therefore, the aim of this clinical study was to prospectively evaluate clinical,
functional, quality of life and survival outcomes after palliative surgery for
vertebral metastases. METHODS: 118 consecutive patients who underwent spinal
surgery for symptomatic vertebral metastases were prospectively followed up for
12 months or until death. Clinical data and data from the European Organization
for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire were obtained
pre- and post-operatively and at regular follow-up intervals. RESULTS: Surgery
was effective in achieving rapid improvement in axial and radicular pain,
neurological deficit, sphincteric dysfunction and ambulatory status, with a
complication rate of 26% and a 12 month mortality rate of 48%. Almost 50% of
patients had complete resolution of back pain, radiculopathy and neurological
deficit. Of the patients who were non-ambulant and incontinent, over 50% regained
ambulatory ability and recovered urinary continence. The overall incidence of
wound infection or breakdown was 6.8% and the local recurrence rate was 8.5%.
There was a highly significant improvement in physical, role, cognitive and
emotional functioning and global health status post-operatively. Greatest
improvement in pain, function and overall quality of life occurred in the early
post-operative period and was maintained until death or during the 12 month
prospective follow-up period. CONCLUSION: The potential for immediate and
prolonged improvement in pain, function and quality of life in patients with
symptomatic vertebral metastases should be considered during the decision-making
process when selecting and counselling patients for surgery.
FAU - Quan, Gerald M Y
AU - Quan GM
AD - Spinal Unit, Department of Orthopaedic Surgery, University Hospital of Bordeaux,
Bordeaux, France. gerald.quan@austin.org.au
FAU - Vital, Jean-Marc
AU - Vital JM
FAU - Aurouer, Nicholas
AU - Aurouer N
FAU - Obeid, Ibrahim
AU - Obeid I
FAU - Palussiere, Jean
AU - Palussiere J
FAU - Diallo, Abou
AU - Diallo A
FAU - Pointillart, Vincent
AU - Pointillart V
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20110626
PL - Germany
TA - Eur Spine J
JT - European spine journal : official publication of the European Spine Society, the
European Spinal Deformity Society, and the European Section of the Cervical Spine
Research Society
JID - 9301980
SB - IM
MH - Adult
MH - Aged
MH - Aged, 80 and over
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Male
MH - Middle Aged
MH - Pain/etiology/*surgery
MH - Pain Measurement
MH - Prospective Studies
MH - *Quality of Life
MH - Spinal Neoplasms/complications/*secondary/*surgery
MH - Treatment Outcome
PMC - PMC3207332
OID - NLM: PMC3207332
EDAT- 2011/06/28 06:00
MHDA- 2012/07/20 06:00
CRDT- 2011/06/28 06:00
PHST- 2010/06/15 [received]
PHST- 2011/05/29 [accepted]
AID - 10.1007/s00586-011-1867-6 [doi]
PST - ppublish
SO - Eur Spine J. 2011 Nov;20(11):1970-8. doi: 10.1007/s00586-011-1867-6. Epub 2011
Jun 26.
PMID- 21698480
OWN - NLM
STAT- MEDLINE
DA - 20111028
DCOM- 20120719
LR - 20150204
IS - 1432-0932 (Electronic)
IS - 0940-6719 (Linking)
VI - 20
IP - 11
DP - 2011 Nov
TI - The effect of repeated restraint stress in pain-related behavior induced by
nucleus pulposus applied on the nerve root in rats.
PG - 1885-91
LID - 10.1007/s00586-011-1877-4 [doi]
AB - INTRODUCTION: Chronic pain has an impact on psychological and social factors. It
is known that stress influences physiological and behavioral changes and affects
several neurotransmitter and hormonal systems. It is also known that
corticosterone is increased by stress. The role of chronic stress in sciatica in
lumbar disc herniation (LDH) in rats has not been investigated. The aim of this
study was to investigate the effect of the restraint stress (RS) on pain-related
behavior induced by application of nucleus pulposus (NP) in rats. MATERIALS AND
METHODS: Adult female Sprague-Dawley rats were divided into six experimental
groups (naive group; naive + RS; sham group; sham + RS; autologous nucleus
pulposus [NP] applied on the left L5 nerve root [NP group]; and NP + RS group).
Von Frey tests were used to test pain-related behavior. Concentrations of plasma
corticosterone were measured to assess changes in levels of endogenous
corticosterone caused by RS. Expression of ATF-3 in the left L5 DRG was examined
by immunohistochemical analyses in each group. RESULTS: Mechanical withdrawal
thresholds of the NP and NP + RS groups were significantly decreased after
surgery compared with the naive group. Although the thresholds in the NP group
recovered after 28 days, the thresholds in the NP + RS group were significantly
decreased during the 42 days after surgery. RS increased the concentration of
plasma corticosterone at 21 and 42 days after surgery. In the NP and the NP + RS
groups, the expression of ATF-3 was significantly increased at 7 days after
surgery. The expression of ATF-3 was sustained for 21 days by RS. CONCLUSION:
Concentrations of plasma corticosterone were increased in three groups that
underwent RS. The pain-related behavior persisted for the long term in the LDH
model. The expression of ATF-3 in DRG neurons increased for 21 days by RS. These
results suggest that RS plays a role in the chronicity of pain-related behavior
in the LDH rats.
FAU - Uesugi, Kazuhide
AU - Uesugi K
AD - Department of Orthopaedic Surgery, Fukushima Medical University School of
Medicine, 1-Hikarigaoka, Fukushima City, Fukushima 960-1295, Japan.
FAU - Sekiguchi, Miho
AU - Sekiguchi M
FAU - Kikuchi, Shin-ichi
AU - Kikuchi S
FAU - Konno, Shin-ichi
AU - Konno S
LA - eng
PT - Journal Article
DEP - 20110623
PL - Germany
TA - Eur Spine J
JT - European spine journal : official publication of the European Spine Society, the
European Spinal Deformity Society, and the European Section of the Cervical Spine
Research Society
JID - 9301980
RN - 0 (Activating Transcription Factor 3)
RN - 0 (Atf3 protein, rat)
RN - W980KJ009P (Corticosterone)
SB - IM
MH - Activating Transcription Factor 3/metabolism
MH - Animals
MH - Behavior, Animal/*physiology
MH - Chronic Pain/metabolism/*physiopathology
MH - Corticosterone/blood
MH - Female
MH - Intervertebral Disc/metabolism/physiopathology
MH - Intervertebral Disc Displacement/metabolism/physiopathology
MH - Neuralgia/metabolism/*physiopathology
MH - Rats
MH - Rats, Sprague-Dawley
MH - Restraint, Physical
MH - Sciatica/etiology/metabolism/physiopathology
MH - Spinal Nerve Roots/metabolism/*physiopathology
MH - Stress, Physiological/*physiology
MH - Stress, Psychological/metabolism/*physiopathology
PMC - PMC3207337
OID - NLM: PMC3207337
EDAT- 2011/06/24 06:00
MHDA- 2012/07/20 06:00
CRDT- 2011/06/24 06:00
PHST- 2011/01/12 [received]
PHST- 2011/06/04 [accepted]
PHST- 2011/05/25 [revised]
AID - 10.1007/s00586-011-1877-4 [doi]
PST - ppublish
SO - Eur Spine J. 2011 Nov;20(11):1885-91. doi: 10.1007/s00586-011-1877-4. Epub 2011
Jun 23.
PMID- 21633793
OWN - NLM
STAT- MEDLINE
DA - 20111028
DCOM- 20120719
LR - 20151119
IS - 1432-0932 (Electronic)
IS - 0940-6719 (Linking)
VI - 20
IP - 11
DP - 2011 Nov
TI - Etanercept attenuates pain-related behavior following compression of the dorsal
root ganglion in the rat.
PG - 1877-84
LID - 10.1007/s00586-011-1854-y [doi]
AB - PURPOSE: TNFalpha is an inflammatory mediator related to neuropathic pain
including sciatica. Much basic research suggests that anti-TNFalpha therapy may
be useful for the treatment of sciatica. The purpose of this study was to clarify
the effects of etanercept in a dorsal root ganglion (DRG) compression model.
METHODS: Adult male Sprague-Dawley rats (200-250 g, n = 60) were used. An
L-shaped stainless rod was used to compress the left L5 DRG in the saline and
etanercept groups. No rod was used in the sham group. In the etanercept group, 1
mg of etanercept was applied locally onto the DRG at the end of surgery. Saline
was applied in the saline and sham groups. On day 3 and day 7 after surgery, the
number of ED1-immunoreactive (IR) cells (macrophages) in the DRG was calculated
by immunohistochemical methods (n = 6). In addition, double-immunofluorescence
labeling for ED1 and TNFalpha was performed. Behavioral testing with von Frey
filaments and a heat stimulator was performed (n = 12). RESULTS: ED1-IR cells in
the DRG significantly increased in the control group compared with the sham group
(p < 0.05). Some ED1-IR cells were co-labeled for TNFalpha. In the etanercept
group, decrease in mechanical threshold was significantly inhibited compared with
the saline group (p < 0.05). Thermal hyperalgesia was observed in the control
group, but in neither the sham nor etanercept group (p < 0.05). CONCLUSION:
Etanercept attenuated the pain-related behavior induced by DRG compression. These
findings suggest that mechanical effects on the DRG might be reduced by
etanercept in addition to the effects on nucleus pulposus in lumbar disc
herniation.
FAU - Watanabe, Kazuyuki
AU - Watanabe K
AD - Department of Orthopaedic Surgery, Fukushima Medical University School of
Medicine, 1 Hikarigaoka, Fukushima, Fukushima 960-1295, Japan. kazu-w@fmu.ac.jp
FAU - Yabuki, Shoji
AU - Yabuki S
FAU - Sekiguchi, Miho
AU - Sekiguchi M
FAU - Kikuchi, Shin-ichi
AU - Kikuchi S
FAU - Konno, Shin-ichi
AU - Konno S
LA - eng
PT - Journal Article
DEP - 20110602
PL - Germany
TA - Eur Spine J
JT - European spine journal : official publication of the European Spine Society, the
European Spinal Deformity Society, and the European Section of the Cervical Spine
Research Society
JID - 9301980
RN - 0 (Anti-Inflammatory Agents, Non-Steroidal)
RN - 0 (Immunoglobulin G)
RN - 0 (Receptors, Tumor Necrosis Factor)
RN - 0 (Tumor Necrosis Factor-alpha)
RN - OP401G7OJC (Etanercept)
SB - IM
MH - Animals
MH - Anti-Inflammatory Agents, Non-Steroidal/pharmacology/*therapeutic use
MH - Behavior, Animal/*drug effects
MH - Etanercept
MH - Ganglia, Spinal/metabolism/*physiopathology
MH - Hyperalgesia/*drug therapy/metabolism/physiopathology
MH - Immunoglobulin G/pharmacology/*therapeutic use
MH - Male
MH - Neuralgia/*drug therapy/metabolism/physiopathology
MH - Pain Measurement
MH - Pain Threshold/drug effects
MH - Rats
MH - Rats, Sprague-Dawley
MH - Receptors, Tumor Necrosis Factor/*therapeutic use
MH - Tumor Necrosis Factor-alpha/metabolism
PMC - PMC3207346
OID - NLM: PMC3207346
EDAT- 2011/06/03 06:00
MHDA- 2012/07/20 06:00
CRDT- 2011/06/03 06:00
PHST- 2011/02/23 [received]
PHST- 2011/05/18 [accepted]
PHST- 2011/04/25 [revised]
AID - 10.1007/s00586-011-1854-y [doi]
PST - ppublish
SO - Eur Spine J. 2011 Nov;20(11):1877-84. doi: 10.1007/s00586-011-1854-y. Epub 2011
Jun 2.
PMID- 21992847
OWN - NLM
STAT- MEDLINE
DA - 20111115
DCOM- 20120314
LR - 20161125
IS - 1969-6213 (Electronic)
IS - 1774-024X (Linking)
VI - 7
IP - 7
DP - 2011 Nov
TI - Three-dimensional optical coherence tomography assessment of coronary wire
re-crossing position during bifurcation stenting.
PG - 886-7
LID - 10.4244/EIJV7I7A138 [doi]
LID - 20111011-02 [pii]
FAU - Okamura, Takayuki
AU - Okamura T
AD - Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi
University Graduate School of Medicine, Ube, Japan. t-okamu@yamaguchi-u.ac.jp
FAU - Yamada, Jutaro
AU - Yamada J
FAU - Nao, Tomoko
AU - Nao T
FAU - Suetomi, Takeshi
AU - Suetomi T
FAU - Maeda, Takao
AU - Maeda T
FAU - Shiraishi, Kohzoh
AU - Shiraishi K
FAU - Miura, Toshiro
AU - Miura T
FAU - Matsuzaki, Masunori
AU - Matsuzaki M
LA - eng
PT - Case Reports
PT - Journal Article
PT - Video-Audio Media
PL - France
TA - EuroIntervention
JT - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on
Interventional Cardiology of the European Society of Cardiology
JID - 101251040
SB - IM
MH - Aged
MH - Angina Pectoris/etiology/therapy
MH - *Angioplasty, Balloon, Coronary/instrumentation
MH - Coronary Angiography
MH - Coronary Artery Disease/complications/diagnostic imaging/pathology/*therapy
MH - Fourier Analysis
MH - Humans
MH - *Imaging, Three-Dimensional
MH - Male
MH - Predictive Value of Tests
MH - Stents
MH - *Tomography, Optical Coherence
MH - Treatment Outcome
EDAT- 2011/10/14 06:00
MHDA- 2012/03/15 06:00
CRDT- 2011/10/14 06:00
AID - 20111011-02 [pii]
AID - 10.4244/EIJV7I7A138 [doi]
PST - ppublish
SO - EuroIntervention. 2011 Nov;7(7):886-7. doi: 10.4244/EIJV7I7A138.
PMID- 21952791
OWN - NLM
STAT- MEDLINE
DA - 20111021
DCOM- 20120731
LR - 20170220
IS - 1432-1106 (Electronic)
IS - 0014-4819 (Linking)
VI - 215
IP - 2
DP - 2011 Nov
TI - Effects of experimentally induced low back pain on the sit-to-stand movement and
electroencephalographic contingent negative variation.
PG - 123-34
LID - 10.1007/s00221-011-2880-z [doi]
AB - It is becoming increasingly evident that people with chronic, recurrent low back
pain (LBP) exhibit changes in cerebrocortical activity that associate with
altered postural coordination, suggesting a need for a better understanding of
how the experience of LBP alters postural coordination and cerebrocortical
activity. To characterize changes in postural coordination and pre-movement
cerebrocortical activity related to the experience of acutely induced LBP, 14
healthy participants with no history of LBP performed sit-to-stand movements in 3
sequential conditions: (1) without experimentally induced LBP; NoPain1, (2) with
movement-associated LBP induced by electrocutaneous stimulation; Pain, and (3)
again without induced LBP; NoPain2. The Pain condition elicited altered muscle
activation and redistributed forces under the seat and feet prior to movement,
decreased peak vertical force exerted under the feet during weight transfer,
longer movement times, as well as decreased and earlier peak hip extension.
Stepwise regression models demonstrated that electroencephalographic amplitudes
of contingent negative variation during the Pain condition significantly
correlated with the participants' change in sit-to-stand measures between the
NoPain1 and Pain conditions, as well as with the subsequent difference in
sit-to-stand measures between the NoPain1 and NoPain2 conditions. The results,
therefore, identify the contingent negative variation as a correlate for the
extent of an individual's LBP-related movement modifications and to the
subsequent change in movement patterns from before to after the experience of
acutely induced LBP, thereby providing a direction for future studies aimed to
understand the neural mechanisms underlying the development of altered movement
patterns with LBP.
FAU - Jacobs, Jesse V
AU - Jacobs JV
AD - Department of Rehabilitation and Movement Science, University of Vermont, 305
Rowell Building, 106 Carrigan Drive, Burlington, VT 05405, USA. JJacobs@uvm.edu
FAU - Yaguchi, Chie
AU - Yaguchi C
FAU - Kaida, Chizuru
AU - Kaida C
FAU - Irei, Mariko
AU - Irei M
FAU - Naka, Masami
AU - Naka M
FAU - Henry, Sharon M
AU - Henry SM
FAU - Fujiwara, Katsuo
AU - Fujiwara K
LA - eng
GR - T32 AR007568/AR/NIAMS NIH HHS/United States
GR - T32 AR007568-10/AR/NIAMS NIH HHS/United States
GR - T32 AR07568/AR/NIAMS NIH HHS/United States
PT - Journal Article
PT - Research Support, N.I.H., Extramural
PT - Research Support, Non-U.S. Gov't
DEP - 20110928
PL - Germany
TA - Exp Brain Res
JT - Experimental brain research
JID - 0043312
SB - IM
MH - Adult
MH - Cerebral Cortex/physiology
MH - Contingent Negative Variation/*physiology
MH - Electroencephalography/methods
MH - Evoked Potentials, Motor/*physiology
MH - Female
MH - Humans
MH - Low Back Pain/etiology/*physiopathology/psychology
MH - Male
MH - Middle Aged
MH - Movement/*physiology
MH - Muscle, Skeletal/*physiology
MH - Posture/*physiology
MH - Young Adult
PMC - PMC3257517
MID - NIHMS342602
OID - NLM: NIHMS342602
OID - NLM: PMC3257517
EDAT- 2011/09/29 06:00
MHDA- 2012/08/01 06:00
CRDT- 2011/09/29 06:00
PHST- 2010/12/08 [received]
PHST- 2011/09/15 [accepted]
AID - 10.1007/s00221-011-2880-z [doi]
PST - ppublish
SO - Exp Brain Res. 2011 Nov;215(2):123-34. doi: 10.1007/s00221-011-2880-z. Epub 2011
Sep 28.
PMID- 22068552
OWN - NLM
STAT- MEDLINE
DA - 20111109
DCOM- 20120309
LR - 20161125
IS - 1439-3646 (Electronic)
IS - 0947-7349 (Linking)
VI - 119
IP - 10
DP - 2011 Nov
TI - Effects of isolated hyperinsulinaemia on sensory function in healthy adults.
PG - 604-9
LID - 10.1055/s-0031-1286316 [doi]
AB - AIMS: Gastrointestinal symptoms such as pain, bloating, nausea and vomiting are
more frequent in pre-diabetic states as well as established diabetes, compared to
healthy individuals. The mechanisms behind these symptoms are multi-factorial and
complex. Furthermore, the effect of isolated hyperinsulinaemia on visceral and
peripheral sensory function is poorly understood. Thus, the current study aimed
to evaluate effects of acute hyperinsulinaemia on sensory function in healthy
adults. METHODS: The sensitivity to electrical oesophageal and median nerve
stimulation was assessed in 15 healthy volunteers together with recording of
evoked brain potentials. All subjects were studied both fasting and using a
euglycaemic hyperinsulinaemic clamp. RESULTS: There was on average a 15%
increased sensitivity to oesophageal electrical stimulation during
hyperinsulinaemia compared to fasting state (P<0.05), but the sensation after
median nerve stimulation remained stable (P=0.58). No significant changes in
latencies and amplitudes of evoked brain potentials were observed after
oesophageal or median nerve stimulation (all P>0.05). CONCLUSIONS: This study
suggests that acute isolated hyperinsulinaemia increases visceral sensitivity,
but does not influence the somatic sensory function. The lack of changes in the
evoked brain potentials may indicate that hyperinsulinaemia affects the visceral
sensory system at a peripheral level. Our result suggests distinct functions of
insulin in the various parts of the nervous system, and yields further clues to
the significance of insulin as a satiety signal.
CI - (c) J. A. Barth Verlag in George Thieme Verlag KG Stuttgart . New York.
FAU - Softeland, E
AU - Softeland E
AD - Department of Medicine, Haukeland University Hospital, Bergen, Norway.
eirik.softeland.med@helse-bergen.no
FAU - Dimcevski, G
AU - Dimcevski G
FAU - Graversen, C
AU - Graversen C
FAU - Nedrebo, B G
AU - Nedrebo BG
FAU - Drewes, A M
AU - Drewes AM
FAU - Frokjaer, J B
AU - Frokjaer JB
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20111108
PL - Germany
TA - Exp Clin Endocrinol Diabetes
JT - Experimental and clinical endocrinology & diabetes : official journal, German
Society of Endocrinology [and] German Diabetes Association
JID - 9505926
RN - 0 (Insulin)
RN - 0 (Insulin, Regular, Pork)
RN - 0 (Recombinant Proteins)
RN - AVT680JB39 (insulin, neutral)
SB - IM
MH - Adult
MH - Electric Stimulation/adverse effects
MH - Esophagus/innervation
MH - Evoked Potentials
MH - Female
MH - Glucose Clamp Technique
MH - Humans
MH - Hyperinsulinism/metabolism/*physiopathology
MH - Insulin/administration & dosage/*metabolism
MH - Insulin, Regular, Pork
MH - Male
MH - Median Nerve/physiology/physiopathology
MH - Middle Aged
MH - Neurons/physiology
MH - Pain Threshold
MH - Peripheral Nerves/physiology/*physiopathology
MH - Reaction Time
MH - Recombinant Proteins/administration & dosage
MH - Satiety Response
MH - *Sensory Thresholds
MH - Young Adult
EDAT- 2011/11/10 06:00
MHDA- 2012/03/10 06:00
CRDT- 2011/11/10 06:00
AID - 10.1055/s-0031-1286316 [doi]
PST - ppublish
SO - Exp Clin Endocrinol Diabetes. 2011 Nov;119(10):604-9. doi:
10.1055/s-0031-1286316. Epub 2011 Nov 8.
PMID- 21922454
OWN - NLM
STAT- MEDLINE
DA - 20111109
DCOM- 20120309
LR - 20161125
IS - 1439-3646 (Electronic)
IS - 0947-7349 (Linking)
VI - 119
IP - 10
DP - 2011 Nov
TI - Hypopituitarism in a HIV affected patient.
PG - 633-5
LID - 10.1055/s-0031-1284366 [doi]
AB - BACKGROUND: The clinical picture of pituitary abscesses may resemble features of
other pituitary pathologies including endocrine deficiencies. The characteristic
radiological changes, namely the ring enhancement, may aid in the diagnostic
work-up of this very rare condition. CASE REPORT: A 40-year-old patient with
longstanding HIV infection presented with headache and fatigue. Testing for
pituitary function confirmed panhypopitutarism. MRI scanning demonstrated an
inhomogeneous pituitary gland with ring-like enhancement and sphenoid sinus
mucosa thickening. Transsphenoidal surgery was performed. Histologically CD68
positive macrophages were found supporting the diagnosis of infectious
hypophysitis. Under hormone replacement therapy and retroviral treatment the
patient clinically normalized. CONCLUSION: A pituitary abscess due to infectious
hypophysitis is a rare cause of pituitary failure. Diagnostic signs on imaging
may help to rapidly distinguish the cause of pituitary deficiency in patients
with HIV infection.
CI - (c) J. A. Barth Verlag in George Thieme Verlag KG Stuttgart . New York.
FAU - Harbeck, B
AU - Harbeck B
AD - University Hospital of Lubeck, Department of Medicine, Lubeck, Germany.
Birgit.Harbeck@uk-sh.de
FAU - Klose, S
AU - Klose S
FAU - Buchfelder, M
AU - Buchfelder M
FAU - Brabant, G
AU - Brabant G
FAU - Lehnert, H
AU - Lehnert H
LA - eng
PT - Case Reports
PT - Journal Article
DEP - 20110915
PL - Germany
TA - Exp Clin Endocrinol Diabetes
JT - Experimental and clinical endocrinology & diabetes : official journal, German
Society of Endocrinology [and] German Diabetes Association
JID - 9505926
RN - 0 (Anti-Retroviral Agents)
SB - IM
MH - Abscess/*complications/diagnostic imaging/physiopathology/therapy
MH - Adult
MH - Anti-Retroviral Agents/therapeutic use
MH - Combined Modality Therapy
MH - Fatigue/etiology
MH - HIV Infections/*complications/drug therapy
MH - Headache/etiology
MH - Hormone Replacement Therapy
MH - Humans
MH - Hypophysectomy
MH - Hypopituitarism/*complications/diagnostic imaging/physiopathology/therapy
MH - Magnetic Resonance Imaging
MH - Male
MH - Pituitary Gland/diagnostic imaging/surgery
MH - Radiography
MH - Treatment Outcome
EDAT- 2011/09/17 06:00
MHDA- 2012/03/10 06:00
CRDT- 2011/09/17 06:00
AID - 10.1055/s-0031-1284366 [doi]
PST - ppublish
SO - Exp Clin Endocrinol Diabetes. 2011 Nov;119(10):633-5. doi:
10.1055/s-0031-1284366. Epub 2011 Sep 15.
PMID- 21942929
OWN - NLM
STAT- MEDLINE
DA - 20111012
DCOM- 20120207
LR - 20131106
IS - 1744-7666 (Electronic)
IS - 1465-6566 (Linking)
VI - 12
IP - 16
DP - 2011 Nov
TI - Extended-release gabapentin in post-herpetic neuralgia.
PG - 2565-71
LID - 10.1517/14656566.2011.622267 [doi]
AB - INTRODUCTION: In early 2011, the FDA gave approval to a new preparation of
gabapentin, licensed for the treatment of post-herpetic neuralgia (PHN).
Gabapentin is commonly used worldwide for multiple indications, which include
neuropathic pain. The new drug combines generic gabapentin with a polymeric
delivery system allowing for extended release and is licensed to be given only as
a once-daily dosing regimen. AREAS COVERED: The article aims to review the
available evidence relating to the pharmacokinetics, tolerability and efficacy of
extended-release gabapentin (GpER). It addresses the current state of the drug's
progress through regulation and the intention of its manufacturer for the market.
EXPERT OPINION: Although GpER has been approved by the FDA for once-daily use in
PHN, there is a relative paucity of data for both its efficacy and the optimum
dosing schedule (once or twice a day). There are no data directly comparing GpER
with the immediate-release preparation or other first-line treatments for PHN.
Therefore, the true status of GpER as a treatment option needs to be enhanced
with additional experimental evidence for its efficacy and favourable side-effect
profile.
FAU - Thomas, Ben
AU - Thomas B
AD - Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH , UK.
FAU - Farquhar-Smith, Paul
AU - Farquhar-Smith P
LA - eng
PT - Journal Article
PT - Review
DEP - 20110927
PL - England
TA - Expert Opin Pharmacother
JT - Expert opinion on pharmacotherapy
JID - 100897346
RN - 0 (Amines)
RN - 0 (Analgesics, Non-Narcotic)
RN - 0 (Cyclohexanecarboxylic Acids)
RN - 0 (Delayed-Action Preparations)
RN - 56-12-2 (gamma-Aminobutyric Acid)
RN - 6CW7F3G59X (gabapentin)
SB - IM
MH - Amines/pharmacokinetics/*therapeutic use
MH - Analgesics, Non-Narcotic/pharmacokinetics/*therapeutic use
MH - Cyclohexanecarboxylic Acids/pharmacokinetics/*therapeutic use
MH - Delayed-Action Preparations
MH - Humans
MH - Neuralgia, Postherpetic/*drug therapy/metabolism
MH - gamma-Aminobutyric Acid/pharmacokinetics/*therapeutic use
EDAT- 2011/09/29 06:00
MHDA- 2012/02/09 06:00
CRDT- 2011/09/28 06:00
AID - 10.1517/14656566.2011.622267 [doi]
PST - ppublish
SO - Expert Opin Pharmacother. 2011 Nov;12(16):2565-71. doi:
10.1517/14656566.2011.622267. Epub 2011 Sep 27.
PMID- 22014012
OWN - NLM