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Alzheimer Prediction Review

Reference

Wen, J., Thibeau-Sutre, E., Samper-Gonzalez, J., Routier, A., Bottani, S., Durrleman, S., ... & Colliot, O. (2019).
Convolutional Neural Networks for Classification of Alzheimer's Disease: Overview and Reproducible Evaluation.
arXiv preprint arXiv:1904.07773. paper

Classification of Alzheimer's Disease

  1. 2D slice-level CNN
  2. 3D patch-level CNN
  3. ROI-based CNN
  4. 3D subject-level CNN
  5. Other approach
  6. Use clinical data

Result Table

Data Leakage (Non Detected) Table

paper AD vs CN sMCI vs pMCI MCI vs CN AD vs MCI Multi-class Approach Data Leakage
Aderghal et al., 2017b 0.84 - 0.65 0.67 - ROI-based Non detected
Aderghal et al., 2018 0.90 - 0.73 0.83 - ROI-based Non detected
Bäckström et al., 2018 0.90 - - - - 3D subject-level Non detected
Cheng et al., 2017 0.87 - - - - 3D patch-level Non detected
Cheng and Liu, 2017 0.85 - - - - 3D subject-level Non detected
Islam and Zhang, 2018 - - - - CN vs mild vs moderate vs severe
0.93
2D slice-level Non detected
Korolev et al., 2017 0.80 - - - - 3D subject-level Non detected
Li et al., 2017 0.88 - - - - 3D subject-level Non detected
Li et al., 2018 0.90 - 0.74 - - 3D patch-level Non detected
Lian et al., 2018 0.90 0.80 - - - 3D patch-level Non detected
Mingxia Liu et al., 2018a 0.91 0.78 - - - 3D patch-level Non detected
Mingxia Liu et al., 2018c 0.91 - - - - 3D patch-level Non detected
Qiu et al., 2018 - 0.83 - - - 2D slice-level Non detected
Senanayake et al., 2018 0.76 - 0.75 0.76 - 3D subject-level Non detected
Shmulev et al., 2018 - 0.62 - - - 3D subject-level Non detected
Valliani and Soni, 2017 0.81 - - - AD vs MCI vs CN
0.57
2D slice-level Non detected

Data Leakage Table

paper AD vs CN sMCI vs pMCI MCI vs CN AD vs MCI Multi-class Approach Data Leakage
Aderghal et al., 2017a 0.91 - 0.66 0.70 - ROI-based Unclear
Basaia et al., 2019 0.99 0.75 - - - 3D subject-level Unclear
Hon and Khan, 2017 0.96 - - - - 2D slice-level Unclear
Hosseini Asl et al., 2018 0.99 - 0.94 1.00 AD vs MCI vs CN
0.95
3D subject-level Unclear
Islam and Zhang, 2017 - - - - CN vs mild vs moderate vs severe
0.74
2D slice-level Unclear
Lin et al., 2018 0.89 0.73 - - - ROI-based Unclear
Manhua Liu et al., 2018 0.85 0.74 - - - 3D patch-level Unclear
Taqi et al., 2018 1.00 - - - - 2D slice-level Unclear
Vu et al., 2017 0.85 - - - - 3D subject-level Unclear
S.-H. Wang et al., 2018 0.98 - - - - 2D slice-level Unclear
Bäckström et al., 2018 0.99 - - - - 3D subject-level clear
Farooq et al., 2017 - - - - AD vs LMCI vs EMCI vs CN
0.99
2D slice-level clear
Gunawardena et al., 2017 - - - - AD vs MCI vs CN
0.96
3D subject-level clear
Vu et al., 2018 0.86 - 0.86 0.77 AD vs MCI vs CN
0.80
3D subject-level clear
Wang et al., 2017 - - 0.91 - - 2D slice-level clear
Wang et al., 2019 0.99 - 0.98 0.94 AD vs MCI vs CN
0.97
3D subject-level clear
Wu et al., 2018 - - - - sMCI vs pMCI vs CN
0.95
2D slice-level clear