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Human in-vivo SV2A PET studies

About this repository:

This repository contains supplementary information for the review Synaptic changes in psychiatric and neurological disorders: state-of-the art of in vivo imaging1. Due to the volume of data extracted, only statistically significant findings were included in the tables within the manuscript. Full data is available to access in this repository.

Tables summarising the results from human in-vivo SV2A PET studies:

file name diagnosis/ participants contents
HC_SV2A.xlsx healthy ageing studies overview+ main results
Neurodegenerative_SV2A.xlsx neurodegenerative disorders studies overview+ main results
Psychiatric_SV2A.xlsx psychiatric disorders studies overview+ main results
Symptom_correlations_SV2A.xlsx all above correlations of SV2A PET measures with symptoms
Other_neuroimaging_measures_correlations_SV2A.xlsx all above correlations of SV2A PET measures with other neuroimaging measures

Footnotes

  1. Howes, O., Marcinkowska, J., Turkheimer, F.E. et al. Synaptic changes in psychiatric and neurological disorders: state-of-the art of in vivo imaging. Neuropsychopharmacol. (2024). https://doi.org/10.1038/s41386-024-01943-x