From 119d4f9520e841f493cd964a78f5c5d85552f988 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Tue, 7 May 2024 13:06:14 -0500 Subject: [PATCH 01/23] Start to read Score6 serology file --- .../unet/parser/util/SerotypeEquivalence.java | 33 +- .../ExpertWhoSerology_20240110_3.54.xml | 221110 +++++++++++++++ 2 files changed, 221142 insertions(+), 1 deletion(-) create mode 100644 src/main/resources/ExpertWhoSerology_20240110_3.54.xml diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index 27d43da9..a648710f 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -21,6 +21,12 @@ */ package org.pankratzlab.unet.parser.util; +import java.io.IOException; +import java.io.InputStream; +import org.jsoup.Jsoup; +import org.jsoup.nodes.Document; +import org.jsoup.nodes.Element; +import org.jsoup.select.Elements; import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.SeroType; @@ -30,9 +36,34 @@ /** Utility class recording the mapping of genotypes to reported serotypes */ public final class SerotypeEquivalence { + private static final String CAREDX_FILE = "ExpertWhoSerology_20240110_3.54.xml"; private static final ImmutableMap equivalencies; static { + equivalencies = buildOldLookup(); + } + + private static ImmutableMap buildNewLookup() { + Builder builder = ImmutableMap.builder(); + + try (InputStream xmlStream = + SerotypeEquivalence.class.getClassLoader().getResourceAsStream(CAREDX_FILE)) { + Document parsed = Jsoup.parse(xmlStream, "UTF-8", "http://example.com"); + + Elements elementsByTag = element.getElementsByTag(SINGLE_LOCUS_TAG); + for (Element e : elementsByTag) { + processLocus(builder, e); + } + + } catch (IOException e) { + e.printStackTrace(); + throw new IllegalStateException("Invalid XML file: " + CAREDX_FILE); + } + + return builder.build(); + } + + private static ImmutableMap buildOldLookup() { // Build the equivalencies map Builder builder = ImmutableMap.builder(); // TODO would be nice to read this from a file instead @@ -72,7 +103,7 @@ public final class SerotypeEquivalence { put(builder, "8", HLALocus.DQB1, "03:02", "03:05"); put(builder, "9", HLALocus.DQB1, "03:03"); - equivalencies = builder.build(); + return builder.build(); } // put method for creating the reference table used in the get method. diff --git a/src/main/resources/ExpertWhoSerology_20240110_3.54.xml b/src/main/resources/ExpertWhoSerology_20240110_3.54.xml new file mode 100644 index 00000000..a5d3148f --- /dev/null +++ b/src/main/resources/ExpertWhoSerology_20240110_3.54.xml @@ -0,0 +1,221110 @@ + + + Expert and WHO for import to Expert and WHO + allele marsh HLADB_3.54.0 + + A*01:01:01:01 + HLA00001 + A1 + A1 + + + A*01:01:01:02N + HLA02169 + NotExpressed + Null + + + A*01:01:01:03 + HLA14798 + A1 + A1 + + + A*01:01:01:04 + HLA15760 + A1 + A1 + + + A*01:01:01:05 + HLA16415 + A1 + A1 + + + A*01:01:01:06 + HLA16417 + A1 + A1 + + + A*01:01:01:07 + HLA16436 + A1 + A1 + + + A*01:01:01:08 + HLA16651 + A1 + A1 + + + A*01:01:01:09 + HLA16652 + A1 + A1 + + + A*01:01:01:10 + HLA16653 + A1 + A1 + + + A*01:01:01:11 + HLA17618 + A1 + A1 + + + A*01:01:01:12 + HLA17985 + A1 + A1 + + + A*01:01:01:13 + HLA18246 + A1 + A1 + + + A*01:01:01:14 + HLA18976 + A1 + A1 + + + A*01:01:01:15 + HLA18991 + A1 + A1 + + + A*01:01:01:16 + HLA19155 + A1 + A1 + + + A*01:01:01:17 + HLA19049 + A1 + A1 + + + A*01:01:01:18 + HLA19098 + A1 + A1 + + + A*01:01:01:19 + HLA19296 + A1 + A1 + + + A*01:01:01:20 + HLA19336 + A1 + A1 + + + A*01:01:01:21 + HLA19701 + A1 + A1 + + + A*01:01:01:22 + HLA21372 + A1 + A1 + + + A*01:01:01:23 + HLA21626 + A1 + A1 + + + A*01:01:01:24 + HLA21738 + A1 + A1 + + + A*01:01:01:25 + HLA23209 + A1 + A1 + + + A*01:01:01:26 + HLA25504 + A1 + A1 + + + 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A*01:31N + HLA03501 + NotExpressed + Null + + + A*01:32 + HLA03522 + Undefined + - + + + A*01:33 + HLA03577 + Undefined + - + + + A*01:35 + HLA03688 + Undefined + - + + + A*01:36 + HLA03789 + Undefined + - + + + A*01:37:01:01 + HLA03831 + Undefined + - + + + A*01:37:01:02 + HLA20355 + Undefined + - + + + A*01:38 + HLA03877 + Undefined + - + + + A*01:39 + HLA03879 + Undefined + - + + + A*01:40 + HLA03881 + Undefined + - + + + A*01:41 + HLA03882 + Undefined + - + + + A*01:42 + HLA03898 + Undefined + - + + + A*01:43 + HLA04122 + Undefined + - + + + A*01:44 + HLA04151 + Undefined + - + + + A*01:45 + HLA04137 + Undefined + - + + + A*01:46 + HLA04469 + Undefined + - + + + A*01:47 + HLA04491 + Undefined + - + + + A*01:48 + HLA04494 + Undefined + - + + + A*01:49 + HLA04525 + Undefined + - + + + A*01:50 + HLA04527 + Undefined + - + + + A*01:51 + HLA04546 + Undefined + - + + + A*01:52:01N + HLA04761 + NotExpressed + Null + + + A*01:52:02N + HLA14127 + NotExpressed + Null + + + A*01:53N + HLA04773 + NotExpressed + Null + + + A*01:54 + HLA04808 + Undefined + - + + + A*01:55 + HLA04811 + Undefined + - + + + A*01:56N + HLA05224 + NotExpressed + Null + + + A*01:57N + HLA05321 + NotExpressed + Null + + + A*01:58 + HLA05323 + Undefined + - + + + A*01:59 + HLA05324 + Undefined + - + + + A*01:60 + HLA05327 + Undefined + - + + + A*01:61 + HLA05329 + Undefined + - + + + A*01:62 + HLA05330 + Undefined + - + + + A*01:63 + HLA05334 + Undefined + - + + + A*01:64 + HLA05338 + Undefined + - + + + A*01:65 + HLA05344 + Undefined + - + + + A*01:66 + HLA05398 + Undefined + - + + + A*01:67:01 + HLA05427 + Undefined + - + + + A*01:67:02 + HLA11215 + Undefined + - + + + A*01:68 + HLA05429 + Undefined + - + + + A*01:69:01 + HLA05432 + Undefined + - + + + A*01:69:02 + HLA07473 + Undefined + - + + + A*01:69:03 + HLA23396 + Undefined + - + + + A*01:70 + HLA05440 + Undefined + - + + + A*01:71 + HLA05539 + Undefined + - + + + A*01:72 + HLA05630 + Undefined + - + + + A*01:73 + HLA05635 + Undefined + - + + + A*01:74 + HLA05648 + Undefined + - + + + A*01:75 + HLA05661 + Undefined + - + + + A*01:76 + HLA05670 + Undefined + - + + + A*01:77 + HLA05838 + Undefined + - + + + A*01:78 + HLA05894 + Undefined + - + + + A*01:79 + HLA05904 + Undefined + - + + + A*01:80 + HLA05906 + Undefined + - + + + A*01:81 + HLA05908 + Undefined + - + + + A*01:82 + HLA05932 + Undefined + - + + + A*01:83:01 + HLA05978 + Undefined + - + + + A*01:83:02 + HLA08640 + Undefined + - + + + A*01:84 + HLA05987 + Undefined + - + + + A*01:85 + HLA06006 + Undefined + - + + + A*01:86 + HLA06341 + Undefined + - + + + A*01:87N + HLA06531 + NotExpressed + Null + + + A*01:88:01 + HLA06549 + Undefined + - + + + A*01:88:02 + HLA16064 + Undefined + - + + + A*01:88:03 + HLA18874 + Undefined + - + + + A*01:89 + HLA06558 + Undefined + - + + + A*01:90 + HLA06561 + Undefined + - + + + A*01:91 + HLA06569 + Undefined + - + + + A*01:92 + HLA06570 + Undefined + - + + + A*01:93 + HLA06571 + Undefined + - + + + A*01:94 + HLA06764 + Undefined + - + + + A*01:95 + HLA06765 + Bw4 + Undefined + - + + + A*01:96 + HLA06787 + Undefined + - + + + A*01:97 + HLA06799 + Undefined + - + + + A*01:98 + HLA06800 + Undefined + - + + + A*01:99 + HLA06801 + Undefined + - + + + A*01:100 + HLA06802 + Undefined + - + + + A*01:101 + HLA06813 + Undefined + - + + + A*01:102 + HLA07351 + Undefined + - + + + A*01:103 + HLA07356 + Undefined + - + + + A*01:104 + HLA07404 + Undefined + - + + + A*01:105 + HLA07596 + Undefined + - + + + A*01:106 + HLA07597 + Undefined + - + + + A*01:107 + HLA07776 + Undefined + - + + + A*01:108 + HLA07806 + Undefined + - + + + A*01:109 + HLA07807 + Undefined + - + + + A*01:110 + HLA07989 + Undefined + - + + + A*01:111 + HLA07991 + Undefined + - + + + A*01:112 + HLA07993 + Undefined + - + + + A*01:113 + HLA08248 + Undefined + - + + + A*01:114 + HLA08557 + Undefined + - + + + A*01:115 + HLA08445 + Undefined + - + + + A*01:116 + HLA08446 + Undefined + - + + + A*01:117 + HLA08447 + Undefined + - + + + A*01:118 + HLA08460 + Undefined + - + + + A*01:119 + HLA08486 + Undefined + - + + + A*01:120 + HLA08636 + Undefined + - + + + A*01:121 + HLA08638 + Undefined + - + + + A*01:122 + HLA08639 + Undefined + - + + + A*01:123N + HLA08895 + NotExpressed + Null + + + A*01:124 + HLA08920 + Undefined + - + + + A*01:125 + HLA08965 + Undefined + - + + + A*01:126 + HLA08967 + Undefined + - + + + A*01:127 + HLA09151 + Undefined + - + + + A*01:128 + HLA09339 + Undefined + - + + + A*01:129 + HLA09416 + Undefined + - + + + A*01:130 + HLA09466 + Undefined + - + + + A*01:131 + HLA09506 + Undefined + - + + + A*01:132 + HLA09507 + Undefined + - + + + A*01:133 + HLA09538 + Undefined + - + + + A*01:134 + HLA09799 + Undefined + - + + + A*01:135 + HLA09800 + Undefined + - + + + A*01:136 + HLA09801 + Undefined + - + + + A*01:137 + HLA09802 + Undefined + - + + + A*01:138 + HLA09803 + Undefined + - + + + A*01:139 + HLA10123 + Undefined + - + + + A*01:140:01 + HLA10166 + Undefined + - + + + A*01:140:02 + HLA26562 + Undefined + - + + + A*01:141 + HLA10179 + Undefined + - + + + A*01:142 + HLA10181 + Undefined + - + + + A*01:143 + HLA10372 + Undefined + - + + + A*01:144 + HLA10385 + Undefined + - + + + A*01:145 + HLA10386 + Undefined + - + + + A*01:146 + HLA10776 + Undefined + - + + + A*01:147Q + HLA10914 + Undefined + - + + + A*01:148 + HLA10978 + Undefined + - + + + A*01:149 + HLA10979 + Undefined + - + + + A*01:150 + HLA10980 + Undefined + - + + + A*01:151 + HLA11214 + Undefined + - + + + A*01:152 + HLA11308 + Undefined + - + + + A*01:153 + HLA11309 + Undefined + - + + + A*01:154 + HLA11400 + Undefined + - + + + A*01:155 + HLA11389 + Undefined + - + + + A*01:156 + HLA11799 + Undefined + - + + + A*01:157 + HLA12078 + Undefined + - + + + A*01:158 + HLA12098 + Undefined + - + + + A*01:159Q + HLA12112 + Undefined + - + + + A*01:160N + HLA12113 + NotExpressed + Null + + + A*01:161 + HLA12159 + Undefined + - + + + A*01:162N + HLA12248 + NotExpressed + Null + + + A*01:163 + HLA12252 + Undefined + - + + + A*01:164 + HLA12463 + Undefined + - + + + A*01:165 + HLA12553 + Undefined + - + + + A*01:166 + HLA12618 + Undefined + - + + + A*01:167 + HLA12725 + Undefined + - + + + A*01:168 + HLA12637 + Undefined + - + + + A*01:169 + HLA12638 + Undefined + - + + + A*01:170 + HLA12861 + Undefined + - + + + A*01:171 + HLA12959 + Undefined + - + + + A*01:172 + HLA12960 + Undefined + - + + + A*01:173 + HLA12961 + Undefined + - + + + A*01:174 + HLA12962 + Undefined + - + + + A*01:175 + HLA12971 + Undefined + - + + + A*01:176 + HLA13189 + Undefined + - + + + A*01:177 + HLA13225 + Undefined + - + + + A*01:178N + HLA13325 + NotExpressed + Null + + + A*01:179N + HLA13326 + NotExpressed + Null + + + A*01:180 + HLA13445 + Undefined + - + + + A*01:181 + HLA13446 + Undefined + - + + + A*01:182 + HLA13447 + Undefined + - + + + A*01:183 + HLA13448 + Undefined + - + + + A*01:184 + HLA13449 + Undefined + - + + + A*01:185 + HLA13450 + Undefined + - + + + A*01:186N + HLA13454 + NotExpressed + Null + + + A*01:187 + HLA13703 + Undefined + - + + + A*01:188 + HLA13727 + Undefined + - + + + A*01:189 + HLA13729 + Undefined + - + + + A*01:190 + HLA13841 + Undefined + - + + + A*01:191 + HLA13845 + Undefined + - + + + A*01:192 + HLA13846 + Undefined + - + + + A*01:193 + HLA13954 + Undefined + - + + + A*01:194 + HLA13763 + Undefined + - + + + A*01:195 + HLA13976 + Undefined + - + + + A*01:196 + HLA14106 + Undefined + - + + + A*01:197 + HLA14283 + Undefined + - + + + A*01:198 + HLA14284 + Undefined + - + + + A*01:199 + HLA14462 + Undefined + - + + + A*01:200 + HLA14466 + Undefined + - + + + A*01:201 + HLA14715 + Undefined + - + + + A*01:202 + HLA14916 + Undefined + - + + + A*01:203 + HLA15245 + Undefined + - + + + A*01:204 + HLA15246 + Undefined + - + + + A*01:205 + HLA15247 + Undefined + - + + + A*01:206 + HLA15248 + Undefined + - + + + A*01:207 + HLA15153 + Undefined + - + + + A*01:208Q + HLA15158 + Undefined + - + + + A*01:209 + HLA15459 + Undefined + - + + + A*01:210:01 + HLA15461 + Undefined + - + + + A*01:210:02 + HLA21760 + Undefined + - + + + A*01:211 + HLA15522 + Undefined + - + + + A*01:212 + HLA15595 + Undefined + - + + + A*01:213 + HLA15605 + Undefined + - + + + A*01:214 + HLA15817 + Undefined + - + + + A*01:215 + HLA15855 + Undefined + - + + + A*01:216 + HLA15873 + Undefined + - + + + A*01:217 + HLA15784 + Undefined + - + + + A*01:218 + HLA16075 + Undefined + - + + + A*01:219 + HLA16076 + Undefined + - + + + A*01:220 + HLA16103 + Undefined + - + + + A*01:221 + HLA16109 + Undefined + - + + + A*01:222 + HLA16111 + Undefined + - + + + A*01:223 + HLA16113 + Undefined + - + + + A*01:224 + HLA16195 + Undefined + - + + + A*01:225 + HLA16200 + Undefined + - + + + A*01:226 + HLA16202 + Undefined + - + + + A*01:227 + HLA16216 + Undefined + - + + + A*01:228Q + HLA16067 + Undefined + - + + + A*01:229 + HLA16097 + Undefined + - + + + A*01:230 + HLA16340 + Undefined + - + + + A*01:231 + HLA16457 + Undefined + - + + + A*01:232:01 + HLA16458 + Undefined + - + + + A*01:232:02 + HLA21417 + Undefined + - + + + A*01:233 + HLA16459 + Undefined + - + + + A*01:234 + HLA16427 + Undefined + - + + + A*01:235 + HLA16987 + Undefined + - + + + A*01:236 + HLA16988 + Undefined + - + + + A*01:237 + HLA17398 + Undefined + - + + + A*01:238 + HLA17484 + Undefined + - + + + A*01:239 + HLA17485 + Undefined + - + + + A*01:240N + HLA17486 + NotExpressed + Null + + + A*01:241 + HLA17650 + Undefined + - + + + A*01:242 + HLA17813 + Undefined + - + + + A*01:243 + HLA17766 + Undefined + - + + + A*01:244 + HLA17780 + Undefined + - + + + A*01:245 + HLA18248 + Undefined + - + + + A*01:246 + HLA18207 + Undefined + - + + + A*01:247N + HLA18215 + NotExpressed + Null + + + A*01:248Q + HLA18216 + Undefined + - + + + A*01:249 + HLA18317 + Undefined + - + + + A*01:250N + HLA18326 + NotExpressed + Null + + + A*01:251 + HLA18341 + Undefined + - + + + A*01:252 + HLA18551 + Undefined + - + + + A*01:253 + HLA18564 + Undefined + - + + + A*01:254 + HLA18878 + Undefined + - + + + A*01:255 + HLA18880 + Undefined + - + + + A*01:256 + HLA18893 + Undefined + - + + + A*01:257 + HLA18899 + Undefined + - + + + A*01:258N + HLA18900 + NotExpressed + Null + + + A*01:259 + HLA18901 + Undefined + - + + + A*01:260 + HLA18903 + Undefined + - + + + A*01:261 + HLA18928 + Undefined + - + + + A*01:262 + HLA19193 + Undefined + - + + + A*01:263 + HLA19535 + Undefined + - + + + A*01:264 + HLA19355 + Undefined + - + + + A*01:265 + HLA19484 + Undefined + - + + + A*01:266:01 + HLA19335 + Undefined + - + + + A*01:266:02 + HLA20331 + Undefined + - + + + A*01:267 + HLA19823 + Undefined + - + + + A*01:268 + HLA19936 + Undefined + - + + + A*01:269N + HLA19951 + NotExpressed + Null + + + A*01:270 + HLA20249 + Undefined + - + + + A*01:271 + HLA20308 + Undefined + - + + + A*01:272 + HLA20406 + Undefined + - + + + A*01:273 + HLA19965 + Undefined + - + + + A*01:274 + HLA20251 + Undefined + - + + + A*01:275 + HLA19997 + Undefined + - + + + A*01:276 + HLA20291 + Undefined + - + + + A*01:277 + HLA19963 + Undefined + - + + + A*01:278 + HLA19987 + Undefined + - + + + A*01:279 + HLA20296 + Undefined + - + + + A*01:280 + HLA20187 + Undefined + - + + + A*01:281Q + HLA20210 + Undefined + - + + + A*01:282 + HLA21387 + Undefined + - + + + A*01:283 + HLA21508 + Undefined + - + + + A*01:284 + HLA21351 + Undefined + - + + + A*01:285N + HLA21236 + NotExpressed + Null + + + A*01:286 + HLA21556 + Undefined + - + + + A*01:287N + HLA21591 + NotExpressed + Null + + + A*01:288 + HLA21279 + Undefined + - + + + A*01:289 + HLA21339 + Bw4 + Undefined + - + + + A*01:290N + HLA21766 + NotExpressed + Null + + + A*01:291 + HLA21854 + Undefined + - + + + A*01:292 + HLA21660 + Undefined + - + + + A*01:293N + HLA21756 + NotExpressed + Null + + + A*01:294 + HLA21836 + Undefined + - + + + A*01:295 + HLA21850 + Undefined + - + + + A*01:296 + HLA21799 + Undefined + - + + + A*01:297 + HLA21661 + Undefined + - + + + A*01:298 + HLA22245 + Bw4 + Undefined + - + + + A*01:299 + HLA22261 + Undefined + - + + + A*01:300 + HLA22508 + Undefined + - + + + A*01:301Q + HLA22341 + Undefined + - + + + A*01:302 + HLA22404 + Undefined + - + + + A*01:303:01 + HLA22656 + Undefined + - + + + A*01:303:02 + HLA26408 + Undefined + - + + + A*01:304 + HLA22655 + Undefined + - + + + A*01:305 + HLA22747 + Undefined + - + + + A*01:306 + HLA22989 + Undefined + - + + + A*01:307 + HLA22943 + Undefined + - + + + A*01:308N + HLA22983 + NotExpressed + Null + + + A*01:309 + HLA23471 + Undefined + - + + + A*01:310 + HLA23810 + Undefined + - + + + A*01:311 + HLA23620 + Undefined + - + + + A*01:312 + HLA23179 + Undefined + - + + + A*01:313 + HLA23778 + Undefined + - + + + A*01:314 + HLA23028 + Undefined + - + + + A*01:315 + HLA23353 + Undefined + - + + + A*01:316 + HLA24321 + Undefined + - + + + A*01:317 + HLA24065 + Undefined + - + + + A*01:318 + HLA23879 + Undefined + - + + + A*01:319 + HLA24219 + Undefined + - + + + A*01:320N + HLA25534 + NotExpressed + Null + + + A*01:321 + HLA24764 + Undefined + - + + + A*01:322 + HLA24522 + Undefined + - + + + A*01:323 + HLA24455 + Undefined + - + + + A*01:324 + HLA24657 + Undefined + - + + + A*01:325 + HLA24666 + Undefined + - + + + A*01:326N + HLA25424 + NotExpressed + Null + + + A*01:327 + HLA24378 + Undefined + - + + + A*01:328N + HLA25473 + NotExpressed + Null + + + A*01:329 + HLA25796 + Undefined + - + + + A*01:330 + HLA25704 + Undefined + - + + + A*01:331 + HLA25927 + Undefined + - + + + A*01:332 + HLA26255 + Undefined + - + + + A*01:333 + HLA26380 + Undefined + - + + + A*01:334 + HLA26489 + Undefined + - + + + A*01:335 + HLA26419 + Undefined + - + + + A*01:336N + HLA26458 + NotExpressed + Null + + + A*01:337 + HLA26527 + Undefined + - + + + A*01:338 + HLA26533 + Undefined + - + + + A*01:339 + HLA26507 + Undefined + - + + + A*01:340 + HLA26498 + Undefined + - + + + A*01:341 + HLA26571 + Undefined + - + + + A*01:342 + HLA26414 + Undefined + - + + + A*01:343 + HLA26720 + Undefined + - + + + A*01:344 + HLA26807 + Undefined + - + + + A*01:345 + HLA27968 + Undefined + - + + + A*01:346 + HLA27970 + Undefined + - + + + A*01:347 + HLA28009 + Undefined + - + + + A*01:348 + HLA28245 + Undefined + - + + + A*01:349 + HLA28423 + Undefined + - + + + A*01:350 + HLA28723 + Undefined + - + + + A*01:351 + HLA28606 + Undefined + - + + + A*01:352 + HLA29044 + Undefined + - + + + A*01:353 + HLA29009 + Undefined + - + + + A*01:354 + HLA29191 + Undefined + - + + + A*01:355N + HLA29296 + NotExpressed + Null + + + A*01:356 + HLA29486 + Undefined + - + + + A*01:357 + HLA29462 + Undefined + - + + + A*01:358 + HLA29498 + Undefined + - + + + A*01:359 + HLA29593 + Undefined + - + + + A*01:360 + HLA29768 + Undefined + - + + + A*01:361N + HLA29711 + NotExpressed + Null + + + A*01:362 + HLA29777 + Undefined + - + + + A*01:363 + HLA29754 + Undefined + - + + + A*01:364 + HLA29724 + Undefined + - + + + A*01:365 + HLA29741 + Undefined + - + + + A*01:366 + HLA29720 + Undefined + - + + + A*01:367 + HLA29805 + Undefined + - + + + A*01:368 + HLA30187 + Undefined + - + + + A*01:369 + HLA30229 + Undefined + - + + + A*01:370 + HLA30091 + Undefined + - + + + A*01:371 + HLA30387 + Undefined + - + + + A*01:372 + HLA30310 + Undefined + - + + + A*01:373 + HLA30024 + Undefined + - + + + A*01:374 + HLA30058 + Undefined + - + + + A*01:375 + HLA30057 + Undefined + - + + + A*01:376 + HLA30049 + Undefined + - + + + A*01:377 + HLA30723 + Undefined + - + + + A*01:378 + HLA31147 + Undefined + - + + + A*01:379N + HLA31283 + NotExpressed + Null + + + A*01:380:01:01 + HLA31234 + Undefined + - + + + A*01:380:01:02 + HLA31544 + Undefined + - + + + A*01:381 + HLA31109 + Undefined + - + + + A*01:382 + HLA31183 + Undefined + - + + + A*01:383 + HLA31279 + Undefined + - + + + A*01:384N + HLA31463 + NotExpressed + Null + + + A*01:385 + HLA31591 + Undefined + - + + + A*01:386 + HLA31605 + Undefined + - + + + A*01:387 + HLA31610 + Undefined + - + + + A*01:388 + HLA31838 + Undefined + - + + + A*01:389 + HLA31641 + Undefined + - + + + A*01:390 + HLA32027 + Undefined + - + + + A*01:391 + HLA31868 + Undefined + - + + + A*01:392 + HLA31959 + Undefined + - + + + A*01:393 + HLA31939 + Undefined + - + + + A*01:394N + HLA31949 + NotExpressed + Null + + + A*01:395 + HLA32545 + Undefined + - + + + A*01:396Q + HLA32528 + Undefined + - + + + A*01:397 + HLA32529 + Undefined + - + + + A*01:398 + HLA32526 + Undefined + - + + + A*01:399 + HLA32391 + Undefined + - + + + A*01:400N + HLA32874 + NotExpressed + Null + + + A*01:401 + HLA32955 + Undefined + - + + + A*01:402 + HLA33081 + Undefined + - + + + A*01:403 + HLA33301 + Undefined + - + + + A*01:404 + HLA33600 + Undefined + - + + + A*01:405 + HLA33615 + Undefined + - + + + A*01:406 + HLA33608 + Undefined + - + + + A*01:407 + HLA33698 + Undefined + - + + + A*01:408 + HLA33815 + Undefined + - + + + A*01:409 + HLA33937 + Undefined + - + + + A*01:410 + HLA34133 + Undefined + - + + + A*01:411N + HLA34064 + NotExpressed + Null + + + A*01:412 + HLA34111 + Undefined + - + + + A*01:413 + HLA34314 + Undefined + - + + + A*01:414 + HLA34316 + Undefined + - + + + A*01:415 + 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HLA24356 + Undefined + - + + + A*02:131:01:03 + HLA25460 + Undefined + - + + + A*02:131:02 + HLA19540 + Undefined + - + + + A*02:131:03 + HLA34730 + Undefined + - + + + A*02:132 + HLA03118 + Undefined + - + + + A*02:133 + HLA03132 + Undefined + - + + + A*02:134 + HLA03144 + Undefined + - + + + A*02:135 + HLA03145 + Undefined + - + + + A*02:136 + HLA03162 + Bw4 + Undefined + - + + + A*02:137 + HLA03181 + Undefined + - + + + A*02:138 + HLA03229 + Undefined + - + + + A*02:139 + HLA03235 + Undefined + - + + + A*02:140 + HLA03241 + Undefined + - + + + A*02:141 + HLA03284 + Undefined + - + + + A*02:142 + HLA03304 + Undefined + - + + + A*02:143 + HLA03305 + Undefined + - + + + A*02:144 + HLA03306 + Undefined + - + + + A*02:145 + HLA03326 + Undefined + - + + + A*02:146 + HLA03330 + Undefined + - + + + A*02:147 + HLA03346 + Undefined + - + + + A*02:148 + HLA03409 + Undefined + - + + + A*02:149:01 + HLA03421 + Undefined + - + + + A*02:149:02 + HLA32488 + Undefined + - + + + A*02:150:01 + HLA03452 + Undefined + - + + + A*02:150:02 + HLA19351 + Undefined + - + + + A*02:151 + HLA03475 + Undefined + - + + + A*02:152 + HLA03497 + Undefined + - + + + A*02:153:01 + HLA03567 + Undefined + - + + + A*02:153:02 + HLA10814 + Undefined + - + + + A*02:154 + HLA03579 + Undefined + - + + + A*02:155 + HLA03580 + Undefined + - + + + A*02:156 + HLA03582 + Undefined + - + + + A*02:157:01 + HLA03629 + Undefined + - + + + A*02:157:02 + HLA14516 + Undefined + - + + + A*02:158 + HLA03652 + Undefined + - + + + A*02:159 + HLA03653 + Undefined + - + + + A*02:160 + HLA03655 + Undefined + - + + + A*02:161 + HLA03657 + Undefined + - + + + A*02:162 + HLA03669 + Undefined + - + + + A*02:163 + HLA03670 + Undefined + - + + + A*02:164:01 + HLA03671 + Undefined + - + + + A*02:164:02 + HLA16098 + Undefined + - + + + A*02:165 + HLA03672 + Undefined + - + + + A*02:166 + HLA03673 + Undefined + - + + + A*02:167 + HLA03721 + Undefined + - + + + A*02:168 + HLA03744 + Undefined + - + + + A*02:169 + HLA03774 + Undefined + - + + + A*02:170 + HLA03776 + Undefined + - + + + A*02:171:01 + HLA03777 + Undefined + - + + + A*02:171:02 + HLA04646 + Undefined + - + + + A*02:172 + HLA03784 + Undefined + - + + + A*02:173 + HLA03785 + Undefined + - + + + A*02:174 + HLA03786 + Undefined + - + + + A*02:175 + HLA03791 + Undefined + - + + + A*02:176 + HLA03795 + Undefined + - + + + A*02:177 + HLA03815 + Undefined + - + + + A*02:178 + HLA03829 + Undefined + - + + + A*02:179 + HLA03833 + Undefined + - + + + A*02:180 + HLA03880 + Undefined + - + + + A*02:181 + HLA03884 + Undefined + - + + + A*02:182 + HLA03886 + Undefined + - + + + A*02:183 + HLA03892 + Undefined + - + + + A*02:184 + HLA03893 + Undefined + - + + + A*02:185 + HLA03895 + Undefined + - + + + A*02:186 + HLA03932 + Undefined + - + + + A*02:187 + HLA04063 + Undefined + - + + + A*02:188 + HLA04064 + Undefined + - + + + A*02:189 + HLA04065 + Undefined + - + + + A*02:190 + HLA03996 + Undefined + - + + + A*02:191 + HLA04018 + Undefined + - + + + A*02:192 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Undefined + - + + + A*02:213 + HLA04972 + Undefined + - + + + A*02:214 + HLA04973 + Undefined + - + + + A*02:215 + HLA04975 + Undefined + - + + + A*02:216 + HLA04976 + Undefined + - + + + A*02:217:01 + HLA04984 + Undefined + - + + + A*02:217:02 + HLA06526 + Undefined + - + + + A*02:218 + HLA04985 + Undefined + - + + + A*02:219 + HLA04986 + Undefined + - + + + A*02:220 + HLA04987 + Undefined + - + + + A*02:221 + HLA04989 + Undefined + - + + + A*02:222N + HLA04990 + NotExpressed + Null + + + A*02:223N + HLA04991 + NotExpressed + Null + + + A*02:224 + HLA05001 + Undefined + - + + + A*02:225N + HLA05002 + NotExpressed + Null + + + A*02:226N + HLA05003 + NotExpressed + Null + + + A*02:227N + HLA05004 + NotExpressed + Null + + + A*02:228 + HLA05005 + Undefined + - + + + A*02:229 + HLA05020 + Undefined + - + + + A*02:230 + HLA04887 + Undefined + - + + + A*02:231 + HLA05037 + Undefined + - + + + A*02:232 + HLA05038 + Undefined + - + + + A*02:233:01 + HLA05039 + Undefined + - + + + A*02:233:02 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Undefined + - + + + A*02:255 + HLA05247 + Undefined + - + + + A*02:256 + HLA05244 + Undefined + - + + + A*02:257 + HLA05307 + Undefined + - + + + A*02:258 + HLA05360 + Undefined + - + + + A*02:259 + HLA05368 + Undefined + - + + + A*02:260 + HLA05373 + Undefined + - + + + A*02:261 + HLA05375 + Undefined + - + + + A*02:262 + HLA05384 + Undefined + - + + + A*02:263 + HLA05399 + Undefined + - + + + A*02:264:01:01 + HLA05420 + Undefined + - + + + A*02:264:01:02 + HLA23510 + Undefined + - + + + A*02:265 + HLA05422 + Undefined + - + + + A*02:266 + HLA05408 + Undefined + - + + + A*02:267 + HLA05523 + Undefined + - + + + A*02:268 + HLA05532 + Undefined + - + + + A*02:269 + HLA05542 + Undefined + - + + + A*02:270 + HLA05549 + Undefined + - + + + A*02:271 + HLA05556 + Undefined + - + + + A*02:272 + HLA05672 + Undefined + - + + + A*02:273 + HLA05676 + Undefined + - + + + A*02:274 + HLA05677 + Undefined + - + + + A*02:275 + HLA05687 + Undefined + - + + + A*02:276 + HLA05691 + Undefined + - + + + A*02:277 + HLA05696 + Undefined + - + + + A*02:278 + HLA05697 + Undefined + - + + + A*02:279 + HLA05801 + Undefined + - + + + A*02:280 + HLA05895 + Undefined + - + + + A*02:281 + HLA05896 + Undefined + - + + + A*02:282 + HLA05897 + Undefined + - + + + A*02:283 + HLA05948 + Undefined + - + + + A*02:284N + HLA05963 + NotExpressed + Null + + + A*02:285 + HLA05991 + Undefined + - + + + A*02:286 + HLA06008 + Undefined + - + + + A*02:287 + HLA06009 + Undefined + - + + + A*02:288 + HLA06016 + Undefined + - + + + A*02:289:01 + HLA06017 + Undefined + - + + + A*02:289:02 + HLA12258 + Undefined + - + + + A*02:290 + HLA06019 + Undefined + - + + + A*02:291 + HLA06077 + Undefined + - + + + A*02:292 + HLA06079 + Undefined + - + + + A*02:293Q + HLA06080 + Undefined + - + + + A*02:294 + HLA06081 + Undefined + - + + + A*02:295 + HLA06082 + Undefined + - + + + A*02:296:01 + HLA06088 + Undefined + - + + + A*02:296:02 + HLA29727 + Undefined + - + + + A*02:297 + HLA06092 + Undefined + - + + + A*02:298 + HLA06099 + Undefined + - + + + A*02:299 + HLA06106 + Undefined + - + + + A*02:300 + HLA06108 + Undefined + - + + + A*02:301N + HLA06109 + NotExpressed + Null + + + A*02:302 + HLA06336 + Undefined + - + + + A*02:303 + HLA06342 + Undefined + - + + + A*02:304 + HLA06346 + Undefined + - + + + A*02:305N + HLA06373 + NotExpressed + Null + + + A*02:306 + HLA06564 + Undefined + - + + + A*02:307 + HLA06565 + Undefined + - + + + A*02:308 + HLA06566 + Undefined + - + + + A*02:309 + HLA06572 + Undefined + - + + + A*02:310 + HLA06576 + Undefined + - + + + A*02:311 + HLA06663 + Undefined + - + + + A*02:312 + HLA06747 + Undefined + - + + + A*02:313 + HLA06758 + Undefined + - + + + A*02:314:01N + HLA06759 + NotExpressed + Null + + + A*02:314:02N + HLA31312 + NotExpressed + Null + + + A*02:315 + HLA06760 + Undefined + - + + + A*02:316 + HLA06767 + Undefined + - + + + A*02:317 + HLA06792 + Undefined + - + + + A*02:318 + HLA06805 + Undefined + - + + + A*02:319 + HLA06821 + Undefined + - + + + A*02:320 + HLA06832 + Undefined + - + + + A*02:321N + HLA07034 + NotExpressed + Null + + + A*02:322 + HLA07037 + Undefined + - + + + A*02:323 + HLA06895 + Undefined + - + + + A*02:324 + HLA06900 + Undefined + - + + + A*02:325 + HLA06912 + Undefined + - + + + A*02:326 + HLA06913 + Undefined + - + + + A*02:327 + HLA07104 + Undefined + - + + + A*02:328 + HLA07279 + Undefined + - + + + A*02:329 + HLA07281 + Undefined + - + + + A*02:330 + HLA07287 + Undefined + - + + + A*02:331 + HLA07291 + Undefined + - + + + A*02:332 + HLA07292 + Undefined + - + + + A*02:333 + HLA07324 + Undefined + - + + + A*02:334 + HLA07342 + Undefined + - + + + A*02:335 + HLA07380 + Undefined + - + + + A*02:336 + HLA07387 + Undefined + - + + + A*02:337 + HLA07430 + Undefined + - + + + A*02:338 + HLA07431 + Undefined + - + + + A*02:339 + HLA07432 + Undefined + - + + + A*02:340 + HLA07433 + Undefined + - + + + A*02:341 + HLA07434 + Undefined + - + + + A*02:342 + HLA07435 + Undefined + - + + + A*02:343 + HLA07437 + Undefined + - + + + A*02:344 + HLA07607 + Undefined + - + + + A*02:345 + HLA07611 + Undefined + - + + + A*02:346 + HLA07612 + Undefined + - + + + A*02:347 + HLA07613 + Undefined + - + + + A*02:348 + HLA07614 + Undefined + - + + + A*02:349 + HLA07618 + Undefined + - + + + A*02:350N + HLA07619 + NotExpressed + Null + + + A*02:351 + HLA07621 + Undefined + - + + + A*02:352 + HLA07622 + Undefined + - + + + A*02:353 + HLA07677 + Undefined + - + + + A*02:354 + HLA07678 + Undefined + - + + + A*02:355 + HLA07747 + Undefined + - + + + A*02:356N + HLA07765 + NotExpressed + Null + + + A*02:357 + HLA07817 + Undefined + - + + + A*02:358 + HLA07821 + Undefined + - + + + A*02:359 + HLA08002 + Undefined + - + + + A*02:360 + HLA08005 + Undefined + - + + + A*02:361 + HLA08007 + Undefined + - + + + A*02:362 + HLA08009 + Undefined + - + + + A*02:363 + HLA08010 + Undefined + - + + + A*02:364 + HLA08011 + Undefined + - + + + A*02:365 + HLA08012 + Undefined + - + + + A*02:366N + HLA08013 + NotExpressed + Null + + + A*02:367 + HLA08016 + Undefined + - + + + A*02:368 + HLA08018 + Undefined + - + + + A*02:369 + HLA08019 + Undefined + - + + + A*02:370 + HLA08021 + Undefined + - + + + A*02:371 + HLA08081 + Undefined + - + + + A*02:372 + HLA08096 + Undefined + - + + + A*02:373N + HLA08129 + NotExpressed + Null + + + A*02:374 + HLA08303 + Undefined + - + + + A*02:375 + HLA08468 + Undefined + - + + + A*02:376 + HLA08558 + Undefined + - + + + A*02:377 + HLA08462 + Undefined + - + + + A*02:378 + HLA08463 + Undefined + - + + + A*02:379 + HLA08464 + Undefined + - + + + A*02:380 + HLA08466 + Undefined + - + + + A*02:381 + HLA08467 + Undefined + - + + + A*02:382 + HLA08493 + Undefined + - + + + A*02:383 + HLA08494 + Undefined + - + + + A*02:384 + HLA08495 + Undefined + - + + + A*02:385 + HLA08496 + Undefined + - + + + A*02:386 + HLA08498 + Undefined + - + + + A*02:387 + HLA08645 + Undefined + - + + + A*02:388 + HLA08646 + Undefined + - + + + A*02:389 + HLA08647 + Undefined + - + + + A*02:390 + HLA08648 + Undefined + - + + + A*02:391 + HLA08649 + Undefined + - + + + A*02:392 + HLA08650 + Undefined + - + + + A*02:393 + HLA08883 + Undefined + - + + + A*02:394 + HLA08888 + Undefined + - + + + A*02:395N + HLA08889 + NotExpressed + Null + + + A*02:396 + HLA08891 + Undefined + - + + + A*02:397 + HLA08896 + Undefined + - + + + A*02:398 + HLA08972 + Undefined + - + + + A*02:399 + HLA08973 + Undefined + - + + + A*02:400 + HLA08974 + Undefined + - + + + A*02:401 + HLA09079 + Undefined + - + + + A*02:402 + HLA09090 + Undefined + - + + + A*02:403 + HLA09099 + Undefined + - + + + A*02:404 + HLA09121 + Undefined + - + + + A*02:405 + HLA09123 + Undefined + - + + + A*02:406 + HLA09125 + Undefined + - + + + A*02:407 + HLA09126 + Undefined + - + + + A*02:408 + HLA09130 + Undefined + - + + + A*02:409 + HLA09163 + Undefined + - + + + A*02:410 + HLA09164 + Undefined + - + + + A*02:411 + HLA09171 + Undefined + - + + + A*02:412 + HLA09298 + Undefined + - + + + A*02:413 + HLA09421 + Undefined + - + + + A*02:414 + HLA09422 + Undefined + - + + + A*02:415 + HLA09448 + Undefined + - + + + A*02:416 + HLA09468 + Undefined + - + + + A*02:417 + HLA09463 + Undefined + - + + + A*02:418 + HLA09481 + Undefined + - + + + A*02:419:01 + HLA09494 + Undefined + - + + + A*02:419:02 + HLA15462 + Undefined + - + + + A*02:420 + HLA09486 + Undefined + - + + + A*02:421 + HLA09548 + Undefined + - + + + A*02:422 + HLA09550 + Undefined + - + + + A*02:423 + HLA09551 + Undefined + - + + + A*02:424 + HLA09553 + Undefined + - + + + A*02:425 + HLA09516 + Undefined + - + + + A*02:426 + HLA09644 + Undefined + - + + + A*02:427 + HLA09662 + Undefined + - + + + A*02:428 + HLA09688 + Undefined + - + + + A*02:429 + HLA09692 + Undefined + - + + + A*02:430 + HLA09693 + Undefined + - + + + A*02:431 + HLA09715 + Undefined + - + + + A*02:432 + HLA09718 + Undefined + - + + + A*02:433 + HLA09808 + Undefined + - + + + A*02:434 + HLA09809 + Undefined + - + + + A*02:435 + HLA09812 + Undefined + - + + + A*02:436 + HLA09815 + Undefined + - + + + A*02:437Q + HLA09819 + Undefined + - + + + A*02:438 + HLA09877 + Undefined + - + + + A*02:439N + HLA10115 + NotExpressed + Null + + + A*02:440Q + HLA10118 + Undefined + - + + + A*02:441 + HLA10165 + Undefined + - + + + A*02:442 + HLA10183 + Undefined + - + + + A*02:443 + HLA10184 + Undefined + - + + + A*02:444 + HLA10185 + Undefined + - + + + A*02:445 + HLA10186 + Undefined + - + + + A*02:446 + HLA10188 + Undefined + - + + + A*02:447 + HLA10190 + Undefined + - + + + A*02:448 + HLA10249 + Undefined + - + + + A*02:449 + HLA10200 + Undefined + - + + + A*02:450 + HLA10213 + Undefined + - + + + A*02:451 + HLA10215 + Undefined + - + + + A*02:452 + HLA10220 + Undefined + - + + + A*02:453 + HLA10222 + Undefined + - + + + A*02:454 + HLA10240 + Undefined + - + + + A*02:455 + HLA10253 + Undefined + - + + + A*02:456 + HLA10266 + Undefined + - + + + A*02:457 + HLA10393 + Undefined + - + + + A*02:458 + HLA10394 + Undefined + - + + + A*02:459 + HLA10395 + Undefined + - + + + A*02:460 + HLA10397 + Undefined + - + + + A*02:461 + HLA10522 + Undefined + - + + + A*02:462 + HLA10523 + Undefined + - + + + A*02:463 + HLA10529 + Undefined + - + + + A*02:464 + HLA10634 + Undefined + - + + + A*02:465 + HLA10654 + Undefined + - + + + A*02:466 + HLA10672 + Undefined + - + + + A*02:467 + HLA10783 + Undefined + - + + + A*02:468:01N + HLA10787 + NotExpressed + Null + + + A*02:468:02N + HLA12427 + NotExpressed + Null + + + A*02:469 + HLA10788 + Undefined + - + + + A*02:470 + HLA10792 + Undefined + - + + + A*02:471 + HLA10793 + Undefined + - + + + A*02:472 + HLA10796 + Undefined + - + + + A*02:473 + HLA10798 + Undefined + - + + + A*02:474 + HLA10800 + Undefined + - + + + A*02:475 + HLA10802 + Undefined + - + + + A*02:476N + HLA10804 + NotExpressed + Null + + + A*02:477 + HLA10808 + Undefined + - + + + A*02:478 + HLA10810 + Undefined + - + + + A*02:479 + HLA10879 + Undefined + - + + + A*02:480 + HLA10882 + Undefined + - + + + A*02:481 + HLA10909 + Undefined + - + + + A*02:482 + HLA10933 + Undefined + - + + + A*02:483 + HLA10935 + Undefined + - + + + A*02:484 + HLA10986 + Undefined + - + + + A*02:485 + HLA10987 + Undefined + - + + + A*02:486 + HLA10988 + Undefined + - + + + A*02:487 + HLA10990 + Undefined + - + + + A*02:488 + HLA11065 + Undefined + - + + + A*02:489 + HLA11219 + Undefined + - + + + A*02:490N + HLA11220 + NotExpressed + Null + + + A*02:491 + HLA11221 + Undefined + - + + + A*02:492 + HLA11222 + Undefined + - + + + A*02:493 + HLA11199 + Undefined + - + + + A*02:494 + HLA11317 + Undefined + - + + + A*02:495 + HLA11405 + Undefined + - + + + A*02:496 + HLA11406 + Undefined + - + + + A*02:497 + HLA11555 + Undefined + - + + + A*02:498 + HLA11408 + Undefined + - + + + A*02:499 + HLA11409 + Undefined + - + + + A*02:500Q + HLA11410 + Undefined + - + + + A*02:501:01N + HLA11411 + NotExpressed + Null + + + A*02:501:02N + HLA34804 + NotExpressed + Null + + + A*02:502 + HLA11412 + Undefined + - + + + A*02:503 + HLA11413 + Undefined + - + + + A*02:504 + HLA11414 + Undefined + - + + + A*02:505 + HLA11469 + Undefined + - + + + A*02:506N + HLA11482 + NotExpressed + Null + + + A*02:507 + HLA11640 + Undefined + - + + + A*02:508 + HLA11643 + Undefined + - + + + A*02:509 + HLA11714 + Undefined + - + + + A*02:510 + HLA11715 + Undefined + - + + + A*02:511 + HLA11730 + Undefined + - + + + A*02:512 + HLA11737 + Undefined + - + + + A*02:513 + HLA11758 + Undefined + - + + + A*02:514N + HLA11808 + NotExpressed + Null + + + A*02:515 + HLA11809 + Undefined + - + + + A*02:516N + HLA11810 + NotExpressed + Null + + + A*02:517 + HLA11812 + Undefined + - + + + A*02:518 + HLA11993 + Undefined + - + + + A*02:519 + HLA11994 + Undefined + - + + + A*02:520 + HLA11995 + Undefined + - + + + A*02:521 + HLA11997 + Undefined + - + + + A*02:522 + HLA11998 + Undefined + - + + + A*02:523 + HLA11943 + Undefined + - + + + A*02:524:01 + HLA11962 + Undefined + - + + + A*02:524:02 + HLA14720 + Undefined + - + + + A*02:525N + HLA12075 + NotExpressed + Null + + + A*02:526 + HLA12092 + Undefined + - + + + A*02:527 + HLA12115 + Undefined + - + + + A*02:528:01 + HLA12116 + Undefined + - + + + A*02:528:02 + HLA16117 + Undefined + - + + + A*02:529 + HLA12119 + Undefined + - + + + A*02:530 + HLA12120 + Undefined + - + + + A*02:531 + HLA12122 + Undefined + - + + + A*02:532 + HLA12143 + Undefined + - + + + A*02:533 + HLA12150 + Undefined + - + + + A*02:534 + HLA12152 + Undefined + - + + + A*02:535 + HLA12156 + Undefined + - + + + A*02:536 + HLA12165 + Undefined + - + + + A*02:537 + HLA12173 + Undefined + - + + + A*02:538 + HLA12179 + Undefined + - + + + A*02:539 + HLA12239 + Undefined + - + + + A*02:540N + HLA12257 + NotExpressed + Null + + + A*02:541 + HLA12408 + Undefined + - + + + A*02:542 + HLA12559 + Undefined + - + + + A*02:543 + HLA12469 + Undefined + - + + + A*02:544 + HLA12471 + Undefined + - + + + A*02:545 + HLA12615 + Undefined + - + + + A*02:546 + HLA12616 + Undefined + - + + + A*02:547 + HLA12683 + Undefined + - + + + A*02:548 + HLA12736 + Undefined + - + + + A*02:549 + HLA12641 + Undefined + - + + + A*02:550 + HLA12642 + Undefined + - + + + A*02:551 + HLA12644 + Undefined + - + + + A*02:552 + HLA12646 + Undefined + - + + + A*02:553 + HLA12647 + Undefined + - + + + A*02:554 + HLA12648 + Undefined + - + + + A*02:555 + HLA12649 + Undefined + - + + + A*02:556 + HLA12973 + Undefined + - + + + A*02:557 + HLA12910 + Undefined + - + + + A*02:558 + HLA13045 + Undefined + - + + + A*02:559 + HLA13050 + Undefined + - + + + A*02:560 + HLA13080 + Undefined + - + + + A*02:561 + HLA13083 + Undefined + - + + + A*02:562 + HLA13084 + Undefined + - + + + A*02:563 + HLA13085 + Undefined + - + + + A*02:564 + HLA13086 + Undefined + - + + + A*02:565 + HLA13088 + Undefined + - + + + A*02:566 + HLA13089 + Undefined + - + + + A*02:567 + HLA13090 + Undefined + - + + + A*02:568 + HLA13092 + Undefined + - + + + A*02:569 + HLA13093 + Undefined + - + + + A*02:570:01 + HLA13196 + Undefined + - + + + A*02:570:02 + HLA19325 + Undefined + - + + + A*02:571 + HLA13236 + Bw4 + Undefined + - + + + A*02:572 + HLA13242 + Undefined + - + + + A*02:573 + HLA13248 + Undefined + - + + + A*02:574 + HLA13458 + Undefined + - + + + A*02:575 + HLA13385 + Undefined + - + + + A*02:576 + HLA13648 + Undefined + - + + + A*02:577 + HLA13731 + Undefined + - + + + A*02:578 + HLA13732 + Undefined + - + + + A*02:579 + HLA13733 + Undefined + - + + + A*02:580 + HLA13734 + Undefined + - + + + A*02:581Q + HLA13849 + Undefined + - + + + A*02:582 + HLA13958 + Undefined + - + + + A*02:583 + HLA13959 + Undefined + - + + + A*02:584 + HLA13960 + Undefined + - + + + A*02:585 + HLA13961 + Undefined + - + + + A*02:586 + HLA13778 + Undefined + - + + + A*02:587 + HLA13772 + Undefined + - + + + A*02:588 + HLA13773 + Undefined + - + + + A*02:589 + HLA14004 + Undefined + - + + + A*02:590 + HLA13991 + Undefined + - + + + A*02:591:01 + HLA14123 + Undefined + - + + + A*02:591:02 + HLA15607 + Undefined + - + + + A*02:592 + HLA14133 + Undefined + - + + + A*02:593 + HLA14134 + Undefined + - + + + A*02:594 + HLA14135 + Undefined + - + + + A*02:595 + HLA14136 + Undefined + - + + + A*02:596 + HLA14137 + Undefined + - + + + A*02:597 + HLA14138 + Undefined + - + + + A*02:598 + HLA14139 + Undefined + - + + + A*02:599 + HLA14289 + Undefined + - + + + A*02:600 + HLA14290 + Undefined + - + + + A*02:601 + HLA14291 + Undefined + - + + + A*02:602 + HLA14396 + Undefined + - + + + A*02:603 + HLA14392 + Undefined + - + + + A*02:604 + HLA14514 + Undefined + - + + + A*02:605Q + HLA14515 + Undefined + - + + + A*02:606 + HLA14517 + Undefined + - + + + A*02:607 + HLA14478 + Undefined + - + + + A*02:608N + HLA14479 + NotExpressed + Null + + + A*02:609 + HLA14460 + Undefined + - + + + A*02:610:01 + HLA14495 + Undefined + - + + + A*02:610:02 + HLA15831 + Undefined + - + + + A*02:611 + HLA14718 + Undefined + - + + + A*02:612 + HLA14719 + Undefined + - + + + A*02:613 + HLA14721 + Undefined + - + + + A*02:614 + HLA14697 + Undefined + - + + + A*02:615 + HLA14919 + Undefined + - + + + A*02:616 + HLA14921 + Undefined + - + + + A*02:617 + HLA14922 + Undefined + - + + + A*02:618Q + HLA14855 + Undefined + - + + + A*02:619:01 + HLA14866 + Undefined + - + + + A*02:619:02 + HLA23730 + Undefined + - + + + A*02:620 + HLA14872 + Undefined + - + + + A*02:621 + HLA14886 + Undefined + - + + + A*02:622N + HLA14892 + NotExpressed + Null + + + A*02:623 + HLA14875 + Undefined + - + + + A*02:624 + HLA14898 + Undefined + - + + + A*02:625 + HLA14880 + Undefined + - + + + A*02:626 + HLA14899 + Undefined + - + + + A*02:627 + HLA14960 + Undefined + - + + + A*02:628 + HLA14966 + Undefined + - + + + A*02:629 + HLA14950 + Undefined + - + + + A*02:630 + HLA15253 + Undefined + - + + + A*02:631 + HLA15254 + Undefined + - + + + A*02:632 + HLA15255 + Undefined + - + + + A*02:633 + HLA15256 + Undefined + - + + + A*02:634 + HLA15257 + Undefined + - + + + A*02:635 + HLA15463 + Undefined + - + + + A*02:636 + HLA15531 + Undefined + - + + + A*02:637 + HLA15532 + Undefined + - + + + A*02:638 + HLA15534 + Undefined + - + + + A*02:639 + HLA15535 + Undefined + - + + + A*02:640 + HLA15536 + Undefined + - + + + A*02:641 + HLA15735 + Undefined + - + + + A*02:642 + HLA15568 + Undefined + - + + + A*02:643N + HLA15580 + NotExpressed + Null + + + A*02:644 + HLA15789 + Undefined + - + + + A*02:645 + HLA15815 + Undefined + - + + + A*02:646 + HLA15828 + Undefined + - + + + A*02:647 + HLA15846 + Undefined + - + + + A*02:648:01 + HLA15858 + Undefined + - + + + A*02:648:02 + HLA26505 + Undefined + - + + + A*02:649 + HLA15859 + Undefined + - + + + A*02:650 + HLA15868 + Undefined + - + + + A*02:651 + HLA15876 + Undefined + - + + + A*02:652 + HLA15958 + Undefined + - + + + A*02:653 + HLA15959 + Undefined + - + + + A*02:654 + HLA15960 + Undefined + - + + + A*02:655 + HLA16070 + Undefined + - + + + A*02:656 + HLA16079 + Undefined + - + + + A*02:657 + HLA16082 + Undefined + - + + + A*02:658 + HLA16090 + Undefined + - + + + A*02:659 + HLA16094 + Undefined + - + + + A*02:660 + HLA16114 + Undefined + - + + + A*02:661 + HLA16213 + Undefined + - + + + A*02:662 + HLA16063 + Undefined + - + + + A*02:663 + HLA16336 + Undefined + - + + + A*02:664 + HLA16399 + Undefined + - + + + A*02:665 + HLA16406 + Undefined + - + + + A*02:666 + HLA16452 + Undefined + - + + + A*02:667 + HLA16463 + Undefined + - + + + A*02:668 + HLA16464 + Undefined + - + + + A*02:669 + HLA16465 + Undefined + - + + + A*02:670 + HLA16807 + Undefined + - + + + A*02:671 + HLA16808 + Undefined + - + + + A*02:672Q + HLA16833 + Undefined + - + + + A*02:673 + HLA16879 + Undefined + - + + + A*02:674 + HLA16880 + Undefined + - + + + A*02:675N + HLA16843 + NotExpressed + Null + + + A*02:676 + HLA16925 + Undefined + - + + + A*02:677 + HLA16926 + Undefined + - + + + A*02:678 + HLA16927 + Undefined + - + + + A*02:679 + HLA16992 + Undefined + - + + + A*02:680 + HLA16871 + Undefined + - + + + A*02:681 + HLA16872 + Undefined + - + + + A*02:682 + HLA17093 + Undefined + - + + + A*02:683 + HLA17047 + Undefined + - + + + A*02:684 + HLA17191 + Undefined + - + + + A*02:685 + HLA17208 + Undefined + - + + + A*02:686 + HLA17209 + Undefined + - + + + A*02:687 + HLA17234 + Undefined + - + + + A*02:688:01 + HLA17317 + Undefined + - + + + A*02:688:02 + HLA26513 + Undefined + - + + + A*02:689 + HLA17399 + Undefined + - + + + A*02:690 + HLA17400 + Undefined + - + + + A*02:691N + HLA17445 + NotExpressed + Null + + + A*02:692 + HLA17450 + Undefined + - + + + A*02:693 + HLA17488 + Undefined + - + + + A*02:694 + HLA17489 + Undefined + - + + + A*02:695 + HLA17586 + Undefined + - + + + A*02:696:01N + HLA17587 + NotExpressed + Null + + + A*02:696:02N + HLA31609 + NotExpressed + Null + + + A*02:697 + HLA17604 + Undefined + - + + + A*02:698 + HLA17821 + Undefined + - + + + A*02:699 + HLA17822 + Undefined + - + + + A*02:700 + HLA17823 + Undefined + - + + + A*02:701 + HLA17824 + Undefined + - + + + A*02:702 + HLA17825 + Undefined + - + + + A*02:703 + HLA17759 + Undefined + - + + + A*02:704 + HLA17781 + Undefined + - + + + A*02:705 + HLA18030 + Undefined + - + + + A*02:706 + HLA18087 + Undefined + - + + + A*02:707 + HLA18137 + Undefined + - + + + A*02:708 + HLA18169 + Undefined + - + + + A*02:709 + HLA18208 + Undefined + - + + + A*02:710N + HLA18214 + NotExpressed + Null + + + A*02:711 + HLA18291 + Undefined + - + + + A*02:712 + HLA18293 + Undefined + - + + + A*02:713 + HLA18297 + Undefined + - + + + A*02:714 + HLA18300 + Undefined + - + + + A*02:715N + HLA18308 + NotExpressed + Null + + + A*02:716 + HLA18313 + Undefined + - + + + A*02:717 + HLA18316 + Undefined + - + + + A*02:718 + HLA18318 + Undefined + - + + + A*02:719 + HLA18319 + Undefined + - + + + A*02:720 + HLA18320 + Undefined + - + + + A*02:721 + HLA18407 + Undefined + - + + + A*02:722 + HLA18543 + Undefined + - + + + A*02:723 + HLA18575 + Undefined + - + + + A*02:724 + HLA18497 + Undefined + - + + + A*02:725 + HLA18587 + Undefined + - + + + A*02:726 + HLA18842 + Undefined + - + + + A*02:727 + HLA18876 + Undefined + - + + + A*02:728Q + HLA18885 + Undefined + - + + + A*02:729 + HLA18886 + Undefined + - + + + A*02:730 + HLA18888 + Undefined + - + + + A*02:731 + HLA18892 + Undefined + - + + + A*02:732 + HLA18906 + Undefined + - + + + A*02:733 + HLA18912 + Undefined + - + + + A*02:734 + HLA18916 + Undefined + - + + + A*02:735 + HLA18921 + Undefined + - + + + A*02:736 + HLA18924 + Undefined + - + + + A*02:737 + HLA18929 + Undefined + - + + + A*02:738 + HLA18930 + Undefined + - + + + A*02:739 + HLA18934 + Undefined + - + + + A*02:740 + HLA18935 + Undefined + - + + + A*02:741 + HLA19021 + Undefined + - + + + A*02:742 + HLA19320 + Undefined + - + + + A*02:743 + HLA19273 + Undefined + - + + + A*02:744 + HLA19490 + Undefined + - + + + A*02:745 + HLA19536 + Undefined + - + + + A*02:746 + HLA19476 + Undefined + - + + + A*02:747 + HLA19313 + Undefined + - + + + A*02:748N + HLA19481 + NotExpressed + Null + + + A*02:749 + HLA19312 + Undefined + - + + + A*02:750 + HLA19409 + Undefined + - + + + A*02:751 + HLA19489 + Undefined + - + + + A*02:752 + HLA19224 + Undefined + - + + + A*02:753 + HLA19498 + Undefined + - + + + A*02:754 + HLA19528 + Undefined + - + + + A*02:755 + HLA20045 + Undefined + - + + + A*02:756 + HLA20188 + Undefined + - + + + A*02:757 + HLA20250 + Undefined + - + + + A*02:758 + HLA20082 + Undefined + - + + + A*02:759 + HLA20247 + Undefined + - + + + A*02:760N + HLA20429 + NotExpressed + Null + + + A*02:761 + HLA19954 + Undefined + - + + + A*02:762 + HLA20177 + Undefined + - + + + A*02:763 + HLA20447 + Undefined + - + + + A*02:764 + HLA20300 + Undefined + - + + + A*02:765 + HLA20499 + Undefined + - + + + A*02:766 + HLA20194 + Undefined + - + + + A*02:767 + HLA20454 + Undefined + - + + + A*02:768 + HLA20492 + Undefined + - + + + A*02:769 + HLA20368 + Undefined + - + + + A*02:770 + HLA19991 + Undefined + - + + + A*02:771 + HLA20381 + Undefined + - + + + A*02:772 + HLA20168 + Undefined + - + + + A*02:773N + HLA20491 + NotExpressed + Null + + + A*02:774 + HLA20473 + Undefined + - + + + A*02:775N + HLA20351 + NotExpressed + Null + + + A*02:776 + HLA20370 + Undefined + - + + + A*02:777 + HLA20279 + Undefined + - + + + A*02:778 + HLA20103 + Undefined + - + + + A*02:779 + HLA20416 + Undefined + - + + + A*02:780 + HLA20185 + Undefined + - + + + A*02:781 + HLA20264 + Undefined + - + + + A*02:782 + HLA21018 + Undefined + - + + + A*02:783 + HLA20643 + Undefined + - + + + A*02:784 + HLA21062 + Undefined + - + + + A*02:785 + HLA20879 + Undefined + - + + + A*02:786 + HLA21057 + Undefined + - + + + A*02:787 + HLA21038 + Undefined + - + + + A*02:788N + HLA21251 + NotExpressed + Null + + + A*02:789N + HLA21334 + NotExpressed + Null + + + A*02:790 + HLA21221 + Undefined + - + + + A*02:791N + HLA21214 + NotExpressed + Null + + + A*02:792N + HLA21340 + NotExpressed + Null + + + A*02:793N + HLA21447 + NotExpressed + Null + + + A*02:794 + HLA21366 + Undefined + - + + + A*02:795Q + HLA21487 + Undefined + - + + + A*02:796N + HLA21411 + NotExpressed + Null + + + A*02:797N + HLA21237 + NotExpressed + Null + + + A*02:798 + HLA21546 + Undefined + - + + + A*02:799 + HLA21265 + Undefined + - + + + A*02:800 + HLA21348 + Undefined + - + + + A*02:801 + HLA21213 + Undefined + - + + + A*02:802 + HLA21346 + Undefined + - + + + A*02:803N + HLA21863 + NotExpressed + Null + + + A*02:804 + HLA21674 + Undefined + - + + + A*02:805Q + HLA21869 + Undefined + - + + + A*02:806N + HLA21641 + NotExpressed + Null + + + A*02:807N + HLA21726 + NotExpressed + Null + + + A*02:808 + HLA21703 + Undefined + - + + + A*02:809 + HLA21894 + Undefined + - + + + A*02:810 + HLA21768 + Undefined + - + + + A*02:811:01 + HLA21658 + Undefined + - + + + A*02:811:02 + HLA34695 + Undefined + - + + + A*02:812 + HLA21839 + Undefined + - + + + A*02:813 + HLA21603 + Undefined + - + + + A*02:814 + HLA21638 + Undefined + - + + + A*02:815 + HLA21785 + Undefined + - + + + A*02:816 + HLA21848 + Undefined + - + + + A*02:817 + HLA21654 + Undefined + - + + + A*02:818 + HLA21862 + Undefined + - + + + A*02:819 + HLA21908 + Undefined + - + + + A*02:820 + HLA21751 + Undefined + - + + + A*02:821 + HLA21666 + Undefined + - + + + A*02:822 + HLA21623 + Undefined + - + + + A*02:823 + HLA21730 + Undefined + - + + + A*02:824 + HLA21878 + Undefined + - + + + A*02:825 + HLA21797 + Undefined + - + + + A*02:826Q + HLA22008 + Undefined + - + + + A*02:827Q + HLA22036 + Undefined + - + + + A*02:828 + HLA21937 + Undefined + - + + + A*02:829 + HLA22227 + Bw4 + Undefined + - + + + A*02:830:01 + HLA22348 + Undefined + - + + + A*02:830:02 + HLA29833 + Undefined + - + + + A*02:831N + HLA22548 + NotExpressed + Null + + + A*02:832N + HLA22680 + NotExpressed + Null + + + A*02:833N + HLA22657 + NotExpressed + Null + + + A*02:834 + HLA22718 + Undefined + - + + + A*02:835 + HLA22706 + Undefined + - + + + A*02:836 + HLA22764 + Undefined + - + + + A*02:837 + HLA22728 + Undefined + - + + + A*02:838 + HLA22831 + Undefined + - + + + A*02:839 + HLA22849 + Undefined + - + + + A*02:840 + HLA22984 + Undefined + - + + + A*02:841 + HLA22895 + Undefined + - + + + A*02:842 + HLA23546 + Undefined + - + + + A*02:843 + HLA23766 + Undefined + - + + + A*02:844 + HLA23568 + Undefined + - + + + A*02:845 + HLA23747 + Undefined + - + + + A*02:846 + HLA23476 + Undefined + - + + + A*02:847 + HLA23738 + Undefined + - + + + A*02:848 + HLA23149 + Undefined + - + + + A*02:849 + HLA23107 + Undefined + - + + + A*02:850 + HLA23683 + Undefined + - + + + A*02:851 + HLA23652 + Undefined + - + + + A*02:852 + HLA23351 + Undefined + - + + + A*02:853 + HLA23472 + Undefined + - + + + A*02:854 + HLA23443 + Undefined + - + + + A*02:855 + HLA23155 + Undefined + - + + + A*02:856 + HLA23456 + Undefined + - + + + A*02:857 + HLA23258 + Undefined + - + + + A*02:858N + HLA23446 + NotExpressed + Null + + + A*02:859 + HLA23228 + Undefined + - + + + A*02:860 + HLA23433 + Undefined + - + + + A*02:861 + HLA23966 + Undefined + - + + + A*02:862 + HLA23969 + Undefined + - + + + A*02:863 + HLA23962 + Undefined + - + + + A*02:864:01:01 + HLA23850 + Undefined + - + + + A*02:864:01:02 + HLA26291 + Undefined + - + + + A*02:865 + HLA24282 + Undefined + - + + + A*02:866 + HLA24184 + Undefined + - + + + A*02:867 + HLA24187 + Undefined + - + + + A*02:868 + HLA24248 + Undefined + - + + + A*02:869 + HLA24033 + Undefined + - + + + A*02:870 + HLA24344 + Undefined + - + + + A*02:871N + HLA23866 + NotExpressed + Null + + + A*02:872 + HLA24275 + Undefined + - + + + A*02:873 + HLA23940 + Undefined + - + + + A*02:874 + HLA23889 + Undefined + - + + + A*02:875 + HLA24034 + Undefined + - + + + A*02:876 + HLA24239 + Undefined + - + + + A*02:877 + HLA23865 + Undefined + - + + + A*02:878 + HLA24355 + Undefined + - + + + A*02:879N + HLA25124 + NotExpressed + Null + + + A*02:880N + HLA24520 + NotExpressed + Null + + + A*02:881 + HLA25283 + Undefined + - + + + A*02:882 + HLA24601 + Undefined + - + + + A*02:883 + HLA24452 + Undefined + - + + + A*02:884:01 + HLA25475 + Undefined + - + + + A*02:884:02 + HLA34659 + Undefined + - + + + A*02:885 + HLA24760 + Undefined + - + + + A*02:886 + HLA24560 + Undefined + - + + + A*02:887N + HLA24435 + NotExpressed + Null + + + A*02:888 + HLA25491 + Undefined + - + + + A*02:889 + HLA25884 + Undefined + - + + + A*02:890 + HLA25672 + Undefined + - + + + A*02:891 + HLA25836 + Undefined + - + + + A*02:892 + HLA25795 + Undefined + - + + + A*02:893 + HLA25907 + Undefined + - + + + A*02:894 + HLA26049 + Undefined + - + + + A*02:895N + HLA25993 + NotExpressed + Null + + + A*02:896N + HLA26108 + NotExpressed + Null + + + A*02:897 + HLA26103 + Undefined + - + + + A*02:898 + HLA26083 + Undefined + - + + + A*02:899 + HLA26140 + Undefined + - + + + A*02:900 + HLA26302 + Undefined + - + + + A*02:901 + HLA26481 + Undefined + - + + + A*02:902 + HLA26547 + Undefined + - + + + A*02:903 + HLA26511 + Undefined + - + + + A*02:904 + HLA26501 + Undefined + - + + + A*02:905 + HLA26425 + Undefined + - + + + A*02:906 + HLA26483 + Undefined + - + + + A*02:907 + HLA26494 + Undefined + - + + + A*02:908 + HLA26485 + Undefined + - + + + A*02:909 + HLA26402 + Undefined + - + + + A*02:910 + HLA26525 + Undefined + - + + + A*02:911 + HLA26552 + Undefined + - + + + A*02:912 + HLA26523 + Undefined + - + + + A*02:913 + HLA26739 + Undefined + - + + + A*02:914 + HLA26712 + Undefined + - + + + A*02:915N + HLA26870 + NotExpressed + Null + + + A*02:916 + HLA26854 + Undefined + - + + + A*02:917 + HLA26861 + Undefined + - + + + A*02:918 + HLA26857 + Undefined + - + + + A*02:919 + HLA26785 + Undefined + - + + + A*02:920 + HLA26864 + Undefined + - + + + A*02:921:01 + HLA26881 + Undefined + - + + + A*02:921:02 + HLA31226 + Undefined + - + + + A*02:922 + HLA26775 + Undefined + - + + + A*02:923 + HLA26797 + Undefined + - + + + A*02:924 + HLA26831 + Undefined + - + + + A*02:925 + HLA26820 + Undefined + - + + + A*02:926 + HLA27275 + Undefined + - + + + A*02:927 + HLA26942 + Undefined + - + + + A*02:928 + HLA27470 + Undefined + - + + + A*02:929 + HLA27471 + Undefined + - + + + A*02:930 + HLA27472 + Undefined + - + + + A*02:931 + HLA27478 + Undefined + - + + + A*02:932 + HLA27481 + Undefined + - + + + A*02:933 + HLA27482 + Undefined + - + + + A*02:934 + HLA27617 + Undefined + - + + + A*02:935 + HLA27893 + Undefined + - + + + A*02:936N + HLA27955 + NotExpressed + Null + + + A*02:937 + HLA27969 + Undefined + - + + + A*02:938 + HLA27987 + Undefined + - + + + A*02:939 + HLA28223 + Undefined + - + + + A*02:940 + HLA28254 + Undefined + - + + + A*02:941 + HLA28405 + Undefined + - + + + A*02:942 + HLA28495 + Undefined + - + + + A*02:943 + HLA28636 + Undefined + - + + + A*02:944 + HLA28697 + Undefined + - + + + A*02:945N + HLA28798 + NotExpressed + Null + + + A*02:946N + HLA28801 + NotExpressed + Null + + + A*02:947 + HLA28895 + Undefined + - + + + A*02:948 + HLA28925 + Undefined + - + + + A*02:949 + HLA28926 + Undefined + - + + + A*02:950 + HLA29204 + Undefined + - + + + A*02:951 + HLA29215 + Undefined + - + + + A*02:952 + HLA29390 + Undefined + - + + + A*02:953 + HLA29483 + Undefined + - + + + A*02:954 + HLA29395 + Undefined + - + + + A*02:955 + HLA29845 + Undefined + - + + + A*02:956 + HLA29857 + Undefined + - + + + A*02:957 + HLA29789 + Undefined + - + + + A*02:958 + HLA29715 + Undefined + - + + + A*02:959 + HLA29706 + Undefined + - + + + A*02:960 + HLA29710 + Undefined + - + + + A*02:961 + HLA29764 + Undefined + - + + + A*02:962 + HLA29752 + Undefined + - + + + A*02:963 + HLA29740 + Undefined + - + + + A*02:964 + HLA29742 + Undefined + - + + + A*02:965 + HLA29781 + Undefined + - + + + A*02:966 + HLA30144 + Undefined + - + + + A*02:967 + HLA30452 + Undefined + - + + + A*02:968 + HLA30299 + Undefined + - + + + A*02:969 + HLA30112 + Undefined + - + + + A*02:970 + HLA30390 + Undefined + - + + + A*02:971 + HLA30223 + Undefined + - + + + A*02:972 + HLA30298 + Undefined + - + + + A*02:973 + HLA30322 + Undefined + - + + + A*02:974 + HLA30093 + Undefined + - + + + A*02:975 + HLA30200 + Undefined + - + + + A*02:976 + HLA30312 + Undefined + - + + + A*02:977 + HLA30362 + Undefined + - + + + A*02:978 + HLA30448 + Undefined + - + + + A*02:979 + HLA30407 + Undefined + - + + + A*02:980 + HLA29940 + Undefined + - + + + A*02:981 + HLA30776 + Undefined + - + + + A*02:982 + HLA30767 + Undefined + - + + + A*02:983 + HLA30810 + Undefined + - + + + A*02:984 + HLA30854 + Undefined + - + + + A*02:985 + HLA30977 + Undefined + - + + + A*02:986 + HLA31230 + Undefined + - + + + A*02:987 + HLA30997 + Undefined + - + + + A*02:988 + HLA31315 + Undefined + - + + + A*02:989N + HLA31190 + NotExpressed + Null + + + A*02:990 + HLA31081 + Undefined + - + + + A*02:991 + HLA31289 + Undefined + - + + + A*02:992 + HLA30897 + Undefined + - + + + A*02:993:01 + HLA31313 + Undefined + - + + + A*02:993:02 + HLA37671 + Undefined + - + + + A*02:994 + HLA30969 + Undefined + - + + + A*02:995 + HLA30890 + Undefined + - + + + A*02:996 + HLA30901 + Undefined + - + + + A*02:997Q + HLA31284 + Undefined + - + + + A*02:998 + HLA31231 + Undefined + - + + + A*02:999N + HLA31089 + NotExpressed + Null + + + A*02:1000 + HLA31495 + Undefined + - + + + A*02:1001 + HLA31839 + Undefined + - + + + A*02:1002 + HLA31410 + Undefined + - + + + A*02:1003 + HLA31448 + Undefined + - + + + A*02:1004 + HLA31578 + Undefined + - + + + A*02:1005 + HLA31654 + Undefined + - + + + A*02:1006N + HLA31656 + NotExpressed + Null + + + A*02:1007Q + HLA31813 + Undefined + - + + + A*02:1008 + HLA32062 + Undefined + - + + + A*02:1009 + HLA31858 + Undefined + - + + + A*02:1010 + HLA32620 + Undefined + - + + + A*02:1011Q + HLA32603 + Undefined + - + + + A*02:1012 + HLA32325 + Undefined + - + + + A*02:1013 + HLA32463 + Undefined + - + + + A*02:1014 + HLA32553 + Undefined + - + + + A*02:1015 + HLA32554 + Undefined + - + + + A*02:1016N + HLA32546 + NotExpressed + Null + + + A*02:1017 + HLA32292 + Undefined + - + + + A*02:1018 + HLA32306 + Undefined + - + + + A*02:1019 + HLA32555 + Undefined + - + + + A*02:1020 + HLA32395 + Undefined + - + + + A*02:1021 + HLA32519 + Undefined + - + + + A*02:1022 + HLA32508 + Undefined + - + + + A*02:1023 + HLA32489 + Undefined + - + + + A*02:1024 + HLA32435 + Undefined + - + + + A*02:1025 + HLA32393 + Undefined + - + + + A*02:1026 + HLA32481 + Undefined + - + + + A*02:1027 + HLA32498 + Undefined + - + + + A*02:1028 + HLA32385 + Undefined + - + + + A*02:1029 + HLA32527 + Undefined + - + + + A*02:1030 + HLA32408 + Undefined + - + + + A*02:1031N + HLA32591 + NotExpressed + Null + + + A*02:1032 + HLA32368 + Undefined + - + + + A*02:1033 + HLA32424 + Undefined + - + + + A*02:1034 + HLA32444 + Undefined + - + + + A*02:1035 + HLA33189 + Undefined + - + + + A*02:1036 + HLA32664 + Undefined + - + + + A*02:1037 + HLA33755 + Undefined + - + + + A*02:1038 + HLA33779 + Undefined + - + + + A*02:1039 + HLA33749 + Undefined + - + + + A*02:1040 + HLA01664 + Undefined + - + + + A*02:1041Q + HLA33944 + Undefined + - + + + A*02:1042 + HLA33943 + Undefined + - + + + A*02:1043 + HLA33869 + Undefined + - + + + A*02:1044 + HLA33919 + Undefined + - + + + A*02:1045Q + HLA34061 + Undefined + - + + + A*02:1046 + HLA34041 + Undefined + - + + + A*02:1047 + HLA34023 + Undefined + - + + + A*02:1048 + HLA34150 + Undefined + - + + + A*02:1049 + HLA34040 + Undefined + - + + + A*02:1050 + HLA34328 + Undefined + - + + + A*02:1051 + HLA34290 + Undefined + - + + + A*02:1052Q + HLA34407 + Undefined + - + + + A*02:1053N + HLA34310 + NotExpressed + Null + + + A*02:1054 + HLA34288 + Undefined + - + + + A*02:1055N + HLA34462 + NotExpressed + Null + + + A*02:1056 + HLA34634 + Undefined + - + + + A*02:1057 + HLA34652 + Undefined + - + + + A*02:1058 + HLA34770 + Undefined + - + + + A*02:1059N + HLA34690 + NotExpressed + Null + + + A*02:1060 + HLA34679 + Undefined + - + + + A*02:1061N + HLA34843 + NotExpressed + Null + + + A*02:1062N + HLA35289 + NotExpressed + Null + + + A*02:1063N + HLA34846 + NotExpressed + Null + + + A*02:1064Q + HLA35616 + Undefined + - + + + A*02:1065 + HLA35565 + Undefined + - + + + A*02:1066 + HLA35982 + Undefined + - + + + A*02:1067 + HLA35979 + Undefined + - + + + A*02:1068Q + HLA35700 + Undefined + - + + + A*02:1069 + HLA35663 + Undefined + - + + + A*02:1070 + HLA35671 + Undefined + - + + + A*02:1071 + HLA35672 + Undefined + - + + + A*02:1072 + HLA35673 + Undefined + - + + + A*02:1073 + HLA35743 + Undefined + - + + + A*02:1074 + HLA35879 + Undefined + - + + + A*02:1075 + HLA36259 + Undefined + - + + + A*02:1076 + HLA36077 + Undefined + - + + + A*02:1077 + HLA36037 + Undefined + - + + + A*02:1078N + HLA36100 + NotExpressed + Null + + + A*02:1079 + HLA36176 + Undefined + - + + + A*02:1080 + HLA36553 + Undefined + - + + + A*02:1081 + HLA36426 + Undefined + - + + + A*02:1082 + HLA36523 + Undefined + - + + + A*02:1083 + HLA36661 + Undefined + - + + + A*02:1084 + HLA36690 + Undefined + - + + + A*02:1085N + HLA36783 + NotExpressed + Null + + + A*02:1086 + HLA36718 + Undefined + - + + + A*02:1087 + HLA36921 + Undefined + - + + + A*02:1088 + HLA36843 + Undefined + - + + + A*02:1089 + HLA36926 + Undefined + - + + + A*02:1090 + HLA36983 + Undefined + - + + + A*02:1091 + HLA36956 + Undefined + - + + + A*02:1092 + HLA36958 + Undefined + - + + + A*02:1093 + HLA37097 + Undefined + - + + + A*02:1094 + HLA37340 + Undefined + - + + + A*02:1095 + HLA37235 + Undefined + - + + + A*02:1096 + HLA37305 + Undefined + - + + + A*02:1097 + HLA37243 + Undefined + - + + + A*02:1098 + HLA37353 + Undefined + - + + + A*02:1099 + HLA37360 + Undefined + - + + + A*02:1100 + HLA37480 + Undefined + - + + + A*02:1101 + HLA37429 + Undefined + - + + + A*02:1102 + HLA37463 + Undefined + - + + + A*02:1103 + HLA37538 + Undefined + - + + + A*02:1104N + HLA37543 + NotExpressed + Null + + + A*02:1105 + HLA37593 + Undefined + - + + + A*02:1106 + HLA37530 + Undefined + - + + + A*02:1107N + HLA37815 + NotExpressed + Null + + + A*02:1108 + HLA37686 + Undefined + - + + + A*02:1109 + HLA37888 + Undefined + - + + + A*02:1110 + HLA37743 + Undefined + - + + + A*02:1111 + HLA37898 + Undefined + - + + + A*02:1112 + HLA37746 + Undefined + - + + + A*02:1113 + HLA37729 + Undefined + - + + + A*02:1114 + HLA37830 + Undefined + - + + + A*02:1115 + HLA37753 + Undefined + - + + + A*02:1116 + HLA38701 + Undefined + - + + + A*02:1117 + HLA37984 + Undefined + - + + + A*02:1118 + HLA37993 + Undefined + - + + + A*02:1119N + HLA38406 + NotExpressed + Null + + + A*02:1120 + HLA38495 + Undefined + - + + + A*02:1121 + HLA38300 + Undefined + - + + + A*02:1122 + HLA38351 + Undefined + - + + + A*02:1123 + HLA38602 + Undefined + - + + + A*02:1124 + HLA38564 + Undefined + - + + + A*02:1125 + HLA38537 + Undefined + - + + + A*02:1126 + HLA38615 + Undefined + - + + + A*02:1127 + HLA38725 + Undefined + - + + + A*02:1128 + HLA38620 + Undefined + - + + + A*03:01:01:01 + HLA00037 + A3 + A3 + + + A*03:01:01:02N + HLA01718 + NotExpressed + Null + + + A*03:01:01:03 + HLA01960 + A3 + A3 + + + A*03:01:01:04 + HLA13768 + A3 + A3 + + + A*03:01:01:05 + HLA13785 + A3 + A3 + + + A*03:01:01:06 + HLA14216 + A3 + A3 + + + A*03:01:01:07 + HLA14827 + A3 + A3 + + + A*03:01:01:08 + HLA15501 + A3 + A3 + + + A*03:01:01:09 + HLA15759 + A3 + A3 + + + A*03:01:01:10 + HLA15761 + A3 + A3 + + + 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A*03:143 + HLA07803 + Undefined + - + + + A*03:144 + HLA07990 + Undefined + - + + + A*03:145:01 + HLA07995 + Undefined + - + + + A*03:145:02 + HLA15403 + Undefined + - + + + A*03:146 + HLA07997 + Undefined + - + + + A*03:147 + HLA07999 + Undefined + - + + + A*03:148 + HLA08000 + Undefined + - + + + A*03:149 + HLA08001 + Undefined + - + + + A*03:150 + HLA08020 + Undefined + - + + + A*03:151 + HLA08281 + Undefined + - + + + A*03:152 + HLA08320 + Bw4 + Undefined + - + + + A*03:153 + HLA08449 + Undefined + - + + + A*03:154:01 + HLA08451 + Undefined + - + + + A*03:154:02 + HLA14199 + Undefined + - + + + A*03:155 + HLA08452 + Undefined + - + + + A*03:156 + HLA08459 + Undefined + - + + + A*03:157:01 + HLA08487 + Undefined + - + + + A*03:157:02 + HLA12465 + Undefined + - + + + A*03:158 + HLA08490 + Undefined + - + + + A*03:159 + HLA08571 + Undefined + - + + + A*03:160 + HLA08642 + Undefined + - + + + A*03:161N + HLA08644 + NotExpressed + Null + + + A*03:162N + HLA08882 + NotExpressed + Null + + + A*03:163 + HLA09337 + Undefined + - + + + A*03:164 + HLA09418 + Undefined + - + + + A*03:165 + HLA09419 + Undefined + - + + + A*03:166 + HLA09420 + Undefined + - + + + A*03:167 + HLA09497 + Undefined + - + + + A*03:168N + HLA09514 + NotExpressed + Null + + + A*03:169 + HLA09540 + Undefined + - + + + A*03:170 + HLA09541 + Undefined + - + + + A*03:171 + HLA09707 + Undefined + - + + + A*03:172 + HLA09804 + Undefined + - + + + A*03:173 + HLA09805 + Undefined + - + + + A*03:174 + HLA09806 + Undefined + - + + + A*03:175 + HLA10226 + Undefined + - + + + A*03:176 + HLA10387 + Undefined + - + + + A*03:177 + HLA10388 + Undefined + - + + + A*03:178N + HLA10389 + NotExpressed + Null + + + A*03:179 + HLA10392 + Undefined + - + + + A*03:180 + HLA10398 + Undefined + - + + + A*03:181 + HLA10671 + Undefined + - + + + A*03:182 + HLA10817 + Undefined + - + + + A*03:183 + HLA10941 + Undefined + - + + + A*03:184 + HLA10981 + Undefined + - + + + A*03:185 + HLA10982 + Undefined + - + + + A*03:186 + HLA11310 + Undefined + - + + + A*03:187 + HLA11313 + Undefined + - + + + A*03:188 + HLA11314 + Undefined + - + + + A*03:189 + HLA11801 + Undefined + - + + + A*03:190 + HLA11803 + Undefined + - + + + A*03:191 + HLA11805 + Undefined + - + + + A*03:192N + HLA11992 + NotExpressed + Null + + + A*03:193 + HLA11938 + Undefined + - + + + A*03:194 + HLA11939 + Undefined + - + + + A*03:195 + HLA11965 + Undefined + - + + + A*03:196 + HLA11966 + Undefined + - + + + A*03:197:01N + HLA11970 + NotExpressed + Null + + + A*03:197:02N + HLA28003 + NotExpressed + Null + + + A*03:198 + HLA12082 + Undefined + - + + + A*03:199 + HLA12111 + Undefined + - + + + A*03:200Q + HLA12146 + Undefined + - + + + A*03:201 + HLA12247 + Undefined + - + + + A*03:202 + HLA12250 + Undefined + - + + + A*03:203 + HLA12251 + Undefined + - + + + A*03:204 + HLA12400 + Undefined + - + + + A*03:205 + HLA12452 + Undefined + - + + + A*03:206 + HLA12461 + Undefined + - + + + A*03:207 + HLA12552 + Undefined + - + + + A*03:208 + HLA12555 + Undefined + - + + + A*03:209 + HLA12556 + Undefined + - + + + A*03:210 + HLA12958 + Undefined + - + + + A*03:211 + HLA12964 + Undefined + - + + + A*03:212 + HLA12965 + Undefined + - + + + A*03:213 + HLA12966 + Undefined + - + + + A*03:214 + HLA12967 + Undefined + - + + + A*03:215 + HLA12968 + Undefined + - + + + A*03:216 + HLA12969 + Undefined + - + + + A*03:217 + HLA12972 + Undefined + - + + + A*03:218 + HLA13046 + Undefined + - + + + A*03:219 + HLA13079 + Bw4 + Undefined + - + + + A*03:220 + HLA13178 + Undefined + - + + + A*03:221 + HLA13232 + Undefined + - + + + A*03:222 + HLA13451 + Undefined + - + + + A*03:223 + HLA13614 + Undefined + - + + + A*03:224 + HLA13619 + Undefined + - + + + A*03:225 + HLA13494 + Undefined + - + + + A*03:226 + HLA13647 + Undefined + - + + + A*03:227 + HLA13701 + Undefined + - + + + A*03:228 + HLA13730 + Undefined + - + + + A*03:229 + HLA13632 + Undefined + - + + + A*03:230 + HLA13847 + Undefined + - + + + A*03:231:01 + HLA14076 + Undefined + - + + + A*03:231:02 + HLA15824 + Undefined + - + + + A*03:232 + HLA14128 + Undefined + - + + + A*03:233 + HLA14129 + Undefined + - + + + A*03:234Q + HLA14103 + Undefined + - + + + A*03:235 + HLA14285 + Undefined + - + + + A*03:236 + HLA14286 + Undefined + - + + + A*03:237 + HLA14505 + Undefined + - + + + A*03:238 + HLA14506 + Undefined + - + + + A*03:239 + HLA14507 + Undefined + - + + + A*03:240 + HLA14508 + Undefined + - + + + A*03:241 + HLA14509 + Undefined + - + + + A*03:242 + HLA14477 + Undefined + - + + + A*03:243 + HLA14704 + Undefined + - + + + A*03:244 + HLA14716 + Undefined + - + + + A*03:245 + HLA14717 + Undefined + - + + + A*03:246 + HLA14702 + Undefined + - + + + A*03:247:01 + HLA14915 + Undefined + - + + + A*03:247:02 + HLA37125 + Undefined + - + + + A*03:248 + HLA14917 + Undefined + - + + + A*03:249 + HLA15249 + Undefined + - + + + A*03:250 + HLA15460 + Undefined + - + + + A*03:251 + HLA15521 + Undefined + - + + + A*03:252 + HLA15523 + Undefined + - + + + A*03:253 + HLA15524 + Undefined + - + + + A*03:254 + HLA15525 + Undefined + - + + + A*03:255 + HLA15526 + Undefined + - + + + A*03:256 + HLA15402 + Undefined + - + + + A*03:257 + HLA15407 + Undefined + - + + + A*03:258 + HLA15819 + Undefined + - + + + A*03:259 + HLA15825 + Undefined + - + + + A*03:260 + HLA15827 + Undefined + - + + + A*03:261 + HLA15836 + Undefined + - + + + A*03:262N + HLA15840 + NotExpressed + Null + + + A*03:263 + HLA15843 + Undefined + - + + + A*03:264 + HLA15845 + Undefined + - + + + A*03:265 + HLA15850 + Undefined + - + + + A*03:266N + HLA16071 + NotExpressed + Null + + + A*03:267 + HLA16074 + Undefined + - + + + A*03:268 + HLA16116 + Undefined + - + + + A*03:269N + HLA16121 + NotExpressed + Null + + + A*03:270 + HLA16194 + Undefined + - + + + A*03:271 + HLA16204 + Undefined + - + + + A*03:272 + HLA16210 + Undefined + - + + + A*03:273 + HLA16327 + Undefined + - + + + A*03:274 + HLA16460 + Undefined + - + + + A*03:275N + HLA16420 + NotExpressed + Null + + + A*03:276 + HLA16805 + Undefined + - + + + A*03:277 + HLA16989 + Undefined + - + + + A*03:278 + HLA16991 + Undefined + - + + + A*03:279N + HLA17066 + NotExpressed + Null + + + A*03:280:01 + HLA17318 + Undefined + - + + + A*03:280:02 + HLA17818 + Undefined + - + + + A*03:281 + HLA17439 + Undefined + - + + + A*03:282 + HLA17487 + Undefined + - + + + A*03:283N + HLA17569 + NotExpressed + Null + + + A*03:284N + HLA17694 + NotExpressed + Null + + + A*03:285 + HLA17815 + Undefined + - + + + A*03:286N + HLA17816 + NotExpressed + Null + + + A*03:287 + HLA17817 + Undefined + - + + + A*03:288 + HLA17819 + Undefined + - + + + A*03:289:01 + HLA17975 + Undefined + - + + + A*03:289:02 + HLA23857 + Undefined + - + + + A*03:290 + HLA18167 + Undefined + - + + + A*03:291 + HLA18314 + Undefined + - + + + A*03:292 + HLA18322 + Undefined + - + + + A*03:293 + HLA18340 + Undefined + - + + + A*03:294 + HLA18834 + Undefined + - + + + A*03:295 + HLA18868 + Undefined + - + + + A*03:296 + HLA18872 + Undefined + - + + + A*03:297N + HLA18882 + NotExpressed + Null + + + A*03:298 + HLA18890 + Undefined + - + + + A*03:299 + HLA18910 + Undefined + - + + + A*03:300 + HLA18919 + Undefined + - + + + A*03:301 + HLA18933 + Undefined + - + + + A*03:302 + HLA18936 + Undefined + - + + + A*03:303 + HLA18972 + Undefined + - + + + A*03:304 + HLA18989 + Undefined + - + + + A*03:305 + HLA18962 + Undefined + - + + + A*03:306 + HLA19337 + Undefined + - + + + A*03:307 + HLA19398 + Undefined + - + + + A*03:308 + HLA19561 + Undefined + - + + + A*03:309 + HLA19442 + Undefined + - + + + A*03:310 + HLA19564 + Undefined + - + + + A*03:311 + HLA19857 + Undefined + - + + + A*03:312 + HLA19937 + Undefined + - + + + A*03:313 + HLA19866 + Undefined + - + + + A*03:314 + HLA19606 + Undefined + - + + + A*03:315 + HLA19695 + Undefined + - + + + A*03:316 + HLA20385 + Undefined + - + + + A*03:317 + HLA20398 + Undefined + - + + + A*03:318 + HLA20471 + Undefined + - + + + A*03:319 + HLA20091 + Undefined + - + + + A*03:320 + HLA20052 + Undefined + - + + + A*03:321 + HLA20505 + Undefined + - + + + A*03:322 + HLA20488 + Undefined + - + + + A*03:323N + HLA21047 + NotExpressed + Null + + + A*03:324 + HLA21022 + Undefined + - + + + A*03:325 + HLA20721 + Undefined + - + + + A*03:326 + HLA21046 + Undefined + - + + + A*03:327 + HLA20565 + Undefined + - + + + A*03:328 + HLA20909 + Undefined + - + + + A*03:329N + HLA21529 + NotExpressed + Null + + + A*03:330N + HLA21347 + NotExpressed + Null + + + A*03:331 + HLA21435 + Undefined + - + + + A*03:332 + HLA21513 + Undefined + - + + + A*03:333 + HLA21305 + Undefined + - + + + A*03:334N + HLA21852 + NotExpressed + Null + + + A*03:335N + HLA22042 + NotExpressed + Null + + + A*03:336N + HLA22017 + NotExpressed + Null + + + A*03:337N + HLA21978 + NotExpressed + Null + + + A*03:338 + HLA22019 + Undefined + - + + + A*03:339 + HLA22053 + Undefined + - + + + A*03:340 + HLA22052 + Undefined + - + + + A*03:341 + HLA22399 + Undefined + - + + + A*03:342N + HLA22364 + NotExpressed + Null + + + A*03:343 + HLA22267 + Undefined + - + + + A*03:344:01 + HLA22492 + Undefined + - + + + A*03:344:02 + HLA36664 + Undefined + - + + + A*03:345:01:01 + HLA22350 + Undefined + - + + + A*03:345:01:02 + HLA26624 + Undefined + - + + + A*03:346 + HLA22324 + Undefined + - + + + A*03:347 + HLA22717 + Undefined + - + + + A*03:348 + HLA22770 + Undefined + - + + + A*03:349 + HLA22751 + Undefined + - + + + A*03:350:01 + HLA22696 + Undefined + - + + + A*03:350:02 + HLA37620 + Undefined + - + + + A*03:351 + HLA22929 + Undefined + - + + + A*03:352 + HLA23012 + Undefined + - + + + A*03:353 + HLA23244 + Undefined + - + + + A*03:354 + HLA23789 + Undefined + - + + + A*03:355 + HLA23642 + Undefined + - + + + A*03:356 + HLA23677 + Undefined + - + + + A*03:357N + HLA23009 + NotExpressed + Null + + + A*03:358 + HLA23495 + Undefined + - + + + A*03:359 + HLA23038 + Undefined + - + + + A*03:360 + HLA23201 + Undefined + - + + + A*03:361 + HLA23691 + Undefined + - + + + A*03:362 + HLA23208 + Undefined + - + + + A*03:363 + HLA23036 + Undefined + - + + + A*03:364N + HLA23539 + NotExpressed + Null + + + A*03:365 + HLA23133 + Undefined + - + + + A*03:366 + HLA24029 + Undefined + - + + + A*03:367 + HLA23863 + Undefined + - + + + A*03:368 + HLA24257 + Undefined + - + + + A*03:369 + HLA24127 + Undefined + - + + + A*03:370 + HLA24405 + Undefined + - + + + A*03:371 + HLA24875 + Undefined + - + + + A*03:372 + HLA25863 + Undefined + - + + + A*03:373 + HLA25606 + Undefined + - + + + A*03:374N + HLA26198 + NotExpressed + Null + + + A*03:375 + HLA26342 + Undefined + - + + + A*03:376 + HLA26335 + Undefined + - + + + A*03:377 + HLA26506 + Undefined + - + + + A*03:378 + HLA26465 + Undefined + - + + + A*03:379 + HLA26428 + Undefined + - + + + A*03:380 + HLA26555 + Undefined + - + + + A*03:381N + HLA26558 + NotExpressed + Null + + + A*03:382 + HLA26518 + Undefined + - + + + A*03:383 + HLA26446 + Undefined + - + + + A*03:384 + HLA26560 + Undefined + - + + + A*03:385 + HLA26399 + Undefined + - + + + A*03:386 + HLA26474 + Undefined + - + + + A*03:387 + HLA26769 + Undefined + - + + + A*03:388Q + HLA27494 + Undefined + - + + + A*03:389 + HLA27497 + Undefined + - + + + A*03:390:01 + HLA27786 + Undefined + - + + + A*03:390:02 + HLA33912 + Undefined + - + + + A*03:391 + HLA27704 + Undefined + - + + + A*03:392 + HLA27896 + Undefined + - + + + A*03:393 + HLA27971 + Undefined + - + + + A*03:394 + HLA27993 + Undefined + - + + + A*03:395 + HLA28002 + Undefined + - + + + A*03:396 + HLA28894 + Undefined + - + + + A*03:397 + HLA28902 + Undefined + - + + + A*03:398 + HLA29013 + Undefined + - + + + A*03:399 + HLA29179 + Undefined + - + + + A*03:400N + HLA29434 + NotExpressed + Null + + + A*03:401 + HLA29788 + Undefined + - + + + A*03:402N + HLA29784 + NotExpressed + Null + + + A*03:403 + HLA29719 + Undefined + - + + + A*03:404N + HLA29707 + NotExpressed + Null + + + A*03:405 + HLA29728 + Undefined + - + + + A*03:406 + HLA29717 + Undefined + - + + + A*03:407 + HLA29761 + Undefined + - + + + A*03:408N + HLA30235 + NotExpressed + Null + + + A*03:409 + HLA29893 + Undefined + - + + + A*03:410 + HLA30198 + Undefined + - + + + A*03:411 + HLA30447 + Undefined + - + + + A*03:412 + HLA30341 + Undefined + - + + + A*03:413 + HLA30027 + Undefined + - + + + A*03:414 + HLA30025 + Undefined + - + + + A*03:415 + HLA30590 + Undefined + - + + + A*03:416 + HLA30816 + Undefined + - + + + A*03:417 + HLA31113 + Undefined + - + + + A*03:418 + HLA31524 + Undefined + - + + + A*03:419 + HLA31644 + Undefined + - + + + A*03:420 + HLA31734 + Undefined + - + + + A*03:421 + HLA31766 + Undefined + - + + + A*03:422 + HLA31749 + Undefined + - + + + A*03:423 + HLA31651 + Undefined + - + + + A*03:424 + HLA31717 + Undefined + - + + + A*03:425 + HLA32593 + Undefined + - + + + A*03:426 + HLA32326 + Undefined + - + + + A*03:427 + HLA32370 + Undefined + - + + + A*03:428 + HLA32410 + Undefined + - + + + A*03:429 + HLA32479 + Undefined + - + + + A*03:430 + HLA32381 + Undefined + - + + + A*03:431 + HLA32440 + Undefined + - + + + A*03:432 + HLA32383 + Undefined + - + + + A*03:433 + HLA32359 + Undefined + - + + + A*03:434 + HLA32807 + Undefined + - + + + A*03:435 + HLA33175 + Undefined + - + + + A*03:436 + HLA33145 + Undefined + - + + + A*03:437Q + HLA33372 + Undefined + - + + + A*03:438 + HLA33494 + Undefined + - + + + A*03:439 + HLA33491 + Undefined + - + + + A*03:440 + HLA33939 + Undefined + - + + + A*03:441 + HLA34048 + Undefined + - + + + A*03:442 + HLA34028 + Undefined + - + + + A*03:443 + HLA34114 + Undefined + - + + + A*03:444 + HLA34339 + Undefined + - + + + A*03:445 + HLA34395 + Undefined + - + + + A*03:446 + HLA34707 + Undefined + - + + + A*03:447 + HLA34713 + Undefined + - + + + A*03:448N + HLA34894 + NotExpressed + Null + + + A*03:449 + HLA35650 + Undefined + - + + + A*03:450 + HLA35980 + Undefined + - + + + A*03:451 + HLA36206 + Undefined + - + + + A*03:452 + HLA36013 + Undefined + - + + + A*03:453 + HLA36233 + Undefined + - + + + A*03:454 + HLA36714 + Undefined + - + + + A*03:455 + HLA36638 + Undefined + - + + + A*03:456 + HLA36613 + Undefined + - + + + A*03:457 + HLA36658 + Undefined + - + + + A*03:458Q + HLA36605 + Undefined + - + + + A*03:459 + HLA37062 + Undefined + - + + + A*03:460 + HLA37234 + Undefined + - + + + A*03:461Q + HLA37606 + Undefined + - + + + A*03:462 + HLA37507 + Undefined + - + + + A*03:463N + HLA37674 + NotExpressed + Null + + + A*03:464Q + HLA37779 + Undefined + - + + + A*03:465 + HLA37802 + Undefined + - + + + A*03:466 + HLA37737 + Undefined + - + + + A*03:467 + HLA37768 + Undefined + - + + + A*03:468 + HLA37740 + Undefined + - + + + A*03:469 + HLA37811 + Undefined + - + + + A*03:470 + HLA37954 + Undefined + - + + + A*03:471 + HLA38154 + Undefined + - + + + A*03:472 + HLA38250 + Undefined + - + + + A*03:473 + HLA38151 + Undefined + - + + + A*11:01:01:01 + HLA00043 + A11 + A11 + + + A*11:01:01:02 + HLA12611 + A11 + A11 + + + A*11:01:01:03 + HLA15502 + A11 + A11 + + + A*11:01:01:04 + HLA16031 + A11 + A11 + + + A*11:01:01:05 + HLA16664 + A11 + A11 + + + 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HLA09412 + Undefined + - + + + A*33:69 + HLA09521 + Undefined + - + + + A*33:70 + HLA09522 + Undefined + - + + + A*33:71 + HLA09775 + Undefined + - + + + A*33:72 + HLA09920 + Undefined + - + + + A*33:73N + HLA10121 + NotExpressed + Null + + + A*33:74N + HLA10169 + NotExpressed + Null + + + A*33:75 + HLA10374 + Undefined + - + + + A*33:76 + HLA10454 + Undefined + - + + + A*33:77 + HLA10456 + Undefined + - + + + A*33:78 + HLA10847 + Undefined + - + + + A*33:79 + HLA10848 + Undefined + - + + + A*33:80N + HLA10850 + NotExpressed + Null + + + A*33:81 + HLA10851 + Undefined + - + + + A*33:82 + HLA10854 + Undefined + - + + + A*33:83 + HLA10855 + Undefined + - + + + A*33:84 + HLA10856 + Undefined + - + + + A*33:85 + HLA10857 + Undefined + - + + + A*33:86 + HLA10956 + Undefined + - + + + A*33:87 + HLA11203 + Undefined + - + + + A*33:88 + HLA11755 + Undefined + - + + + A*33:89 + HLA11778 + Undefined + - + + + A*33:90 + HLA11779 + Undefined + - + + + A*33:91 + HLA11982 + Undefined + - + + + A*33:92 + HLA11983 + Undefined + - + + + A*33:93 + HLA12101 + Undefined + - + + + A*33:94 + HLA12240 + Undefined + - + + + A*33:95 + HLA12867 + Undefined + - + + + A*33:96N + HLA12924 + NotExpressed + Null + + + A*33:97 + HLA13209 + Undefined + - + + + A*33:98 + HLA13429 + Undefined + - + + + A*33:99 + HLA13433 + Undefined + - + + + A*33:100 + HLA13720 + Undefined + - + + + A*33:101 + HLA13721 + Undefined + - + + + A*33:102 + HLA13629 + Undefined + - + + + A*33:103 + HLA13833 + Undefined + - + + + A*33:104 + HLA13834 + Undefined + - + + + A*33:105 + HLA14279 + Undefined + - + + + A*33:106 + HLA14425 + Undefined + - + + + A*33:107 + HLA14706 + Undefined + - + + + A*33:108 + HLA14693 + Undefined + - + + + A*33:109 + HLA14901 + Undefined + - + + + A*33:110 + HLA14881 + Undefined + - + + + A*33:111 + HLA14940 + Undefined + - + + + A*33:112 + HLA15223 + Undefined + - + + + A*33:113 + HLA15224 + Undefined + - + + + A*33:114 + HLA15227 + Undefined + - + + + A*33:115 + HLA15452 + Undefined + - 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Undefined + - + + + A*68:76:02 + HLA12105 + Undefined + - + + + A*68:77 + HLA06540 + Undefined + - + + + A*68:78 + HLA06541 + Undefined + - + + + A*68:79 + HLA06748 + Undefined + - + + + A*68:80 + HLA06739 + Undefined + - + + + A*68:81 + HLA06796 + Undefined + - + + + A*68:82 + HLA06806 + Undefined + - + + + A*68:83 + HLA06836 + Undefined + - + + + A*68:84 + HLA07290 + Undefined + - + + + A*68:85 + HLA07350 + Undefined + - + + + A*68:86 + HLA07571 + Undefined + - + + + A*68:87 + HLA07581 + Undefined + - + + + A*68:88 + HLA07773 + Undefined + - + + + A*68:89 + HLA08043 + Undefined + - + + + A*68:90 + HLA08044 + Undefined + - + + + A*68:91 + HLA08045 + Undefined + - + + + A*68:92 + HLA08051 + Undefined + - + + + A*68:93 + HLA08057 + Undefined + - + + + A*68:94N + HLA08282 + NotExpressed + Null + + + A*68:95 + HLA08619 + Undefined + - + + + A*68:96 + HLA08803 + Undefined + - + + + A*68:97 + HLA08940 + Undefined + - + + + A*68:98 + HLA08948 + Undefined + - + + + A*68:99:01 + HLA09108 + Undefined + - + + + A*68:99:02 + HLA33721 + Undefined + - + + + A*68:100 + HLA09333 + Undefined + - + + + A*68:101:01 + HLA09659 + Undefined + - + + + A*68:101:02 + HLA20254 + Undefined + - + + + A*68:102 + HLA09789 + Undefined + - + + + A*68:103:01 + HLA09918 + Undefined + - + + + A*68:103:02 + HLA12080 + Undefined + - + + + A*68:104:01 + HLA09919 + Undefined + - + + + A*68:104:02 + HLA11634 + Undefined + - + + + A*68:105:01:01 + HLA10122 + Undefined + - + + + A*68:105:01:02 + HLA33387 + Undefined + - + + + A*68:106 + HLA10126 + Undefined + - + + + A*68:107 + HLA10861 + Undefined + - + + + A*68:108 + HLA10877 + Undefined + - + + + A*68:109 + HLA10910 + Undefined + - + + + A*68:110 + HLA10963 + Undefined + - + + + A*68:111 + HLA10973 + Undefined + - + + + A*68:112:01 + HLA11208 + Undefined + - + + + A*68:112:02 + HLA13840 + Undefined + - + + + A*68:113:01 + HLA11765 + Undefined + - + + + A*68:113:02 + HLA27983 + Undefined + - + + + A*68:114:01 + HLA11791 + Undefined + - + + + A*68:114:02 + HLA30052 + Undefined + - + + + A*68:115 + HLA11792 + Undefined + - + + + A*68:116 + HLA11964 + Undefined + - + + + A*68:117 + HLA11971 + Undefined + - + + + A*68:118 + HLA12076 + Undefined + - + + + A*68:119:01 + HLA12079 + Undefined + - + + + A*68:119:02 + HLA13208 + Undefined + - + + + A*68:120N + HLA12148 + NotExpressed + Null + + + A*68:121:01 + HLA12164 + Undefined + - + + + A*68:121:02 + HLA18134 + Undefined + - + + + A*68:122 + HLA12454 + Undefined + - + + + A*68:123 + HLA12457 + Undefined + - + + + A*68:124 + HLA12548 + Undefined + - + + + A*68:125 + HLA12623 + Undefined + - + + + A*68:126 + HLA12624 + Undefined + - + + + A*68:127 + HLA12628 + Undefined + - + + + A*68:128 + HLA12927 + Undefined + - + + + A*68:129 + HLA12936 + Undefined + - + + + A*68:130:01 + HLA12937 + Undefined + - + + + A*68:130:02 + HLA16359 + Undefined + - + + + A*68:131 + HLA12942 + Undefined + - + + + A*68:132 + HLA12943 + Undefined + - + + + A*68:133 + HLA13439 + Undefined + - + + + A*68:134 + HLA13725 + Undefined + - + + + A*68:135 + HLA13838 + Undefined + - + + + A*68:136 + HLA13839 + Undefined + - + + + A*68:137 + HLA13789 + Undefined + - + + + A*68:138 + HLA14280 + Undefined + - + + + A*68:139 + HLA14223 + Undefined + - + + + A*68:140 + HLA14400 + Undefined + - + + + A*68:141 + HLA14432 + Undefined + - + + + A*68:142N + HLA14485 + NotExpressed + Null + + + A*68:143 + HLA14710 + Undefined + - + + + A*68:144 + HLA14692 + Undefined + - + + + A*68:145 + HLA14908 + Undefined + - + + + A*68:146 + HLA14909 + Undefined + - + + + A*68:147 + HLA15228 + Undefined + - + + + A*68:148Q + HLA15237 + Undefined + - + + + A*68:149 + HLA15455 + Undefined + - + + + A*68:150 + HLA15517 + Undefined + - + + + A*68:151 + HLA15733 + Undefined + - + + + A*68:152 + HLA15572 + Undefined + - + + + A*68:153 + HLA15834 + Undefined + - + + + A*68:154 + HLA15848 + Undefined + - + + + A*68:155 + HLA15874 + Undefined + - + + + A*68:156 + HLA15875 + Undefined + - + + + A*68:157 + HLA15952 + Undefined + - + + + A*68:158 + HLA16084 + Undefined + - + + + A*68:159Q + HLA16120 + Undefined + - + + + A*68:160 + HLA16445 + Undefined + - + + + A*68:161 + HLA16449 + Undefined + - + + + A*68:162 + HLA16451 + Undefined + - + + + A*68:163 + HLA16435 + Undefined + - + + + A*68:164:01 + HLA16649 + Undefined + - + + + A*68:164:02 + HLA37034 + Undefined + - + + + A*68:165 + HLA16978 + Undefined + - + + + A*68:166 + HLA16979 + Undefined + - + + + A*68:167 + HLA17325 + Undefined + - + + + A*68:168 + HLA17732 + Undefined + - + + + A*68:169 + HLA17728 + Undefined + - + + + A*68:170 + HLA17799 + Undefined + - + + + A*68:171:01N + HLA17805 + NotExpressed + Null + + + A*68:171:02N + HLA22611 + NotExpressed + Null + + + A*68:172 + HLA17806 + Undefined + - + + + A*68:173 + HLA17807 + Undefined + - + + + A*68:174 + HLA18071 + Undefined + - + + + A*68:175:01 + HLA18303 + Undefined + - + + + A*68:175:02 + HLA34374 + Undefined + - + + + A*68:176:01 + HLA18338 + Undefined + - + + + A*68:176:02 + HLA34342 + Undefined + - + + + A*68:177 + HLA18548 + Undefined + - + + + A*68:178 + HLA18984 + Undefined + - + + + A*68:179 + HLA19264 + Undefined + - + + + A*68:180 + HLA19423 + Undefined + - + + + A*68:181N + HLA19512 + NotExpressed + Null + + + A*68:182N + HLA19291 + NotExpressed + Null + + + A*68:183 + HLA19324 + Undefined + - + + + A*68:184 + HLA19565 + Undefined + - + + + A*68:185 + HLA19931 + Undefined + - + + + A*68:186 + HLA19674 + Undefined + - + + + A*68:187 + HLA20070 + Undefined + - + + + A*68:188 + HLA20229 + Undefined + - + + + A*68:189 + HLA20256 + Undefined + - + + + A*68:190:01 + HLA20053 + Undefined + - + + + A*68:190:02 + HLA38405 + Undefined + - + + + A*68:191 + HLA20134 + Undefined + - + + + A*68:192 + HLA20576 + Undefined + - + + + A*68:193 + HLA21142 + Undefined + - + + + A*68:194 + HLA21140 + Undefined + - + + + A*68:195 + HLA21085 + Undefined + - + + + A*68:196 + HLA20641 + Undefined + - + + + A*68:197 + HLA20709 + Undefined + - + + + A*68:198 + HLA21587 + Undefined + - + + + A*68:199N + HLA21181 + NotExpressed + Null + + + A*68:200 + HLA21172 + Undefined + - + + + A*68:201 + HLA21588 + Undefined + - + + + A*68:202 + HLA21877 + Undefined + - + + + A*68:203N + HLA21759 + NotExpressed + Null + + + A*68:204 + HLA21731 + Undefined + - + + + A*68:205N + HLA21790 + NotExpressed + Null + + + A*68:206 + HLA21993 + Undefined + - + + + A*68:207 + HLA22182 + Undefined + - + + + A*68:208 + HLA22003 + Undefined + - + + + A*68:209 + HLA22174 + Undefined + - + + + A*68:210N + HLA22564 + NotExpressed + Null + + + A*68:211 + HLA23001 + Undefined + - + + + A*68:212 + HLA22937 + Undefined + - + + + A*68:213N + HLA23442 + NotExpressed + Null + + + A*68:214 + HLA23214 + Undefined + - + + + A*68:215 + HLA23524 + Undefined + - + + + A*68:216N + HLA23710 + NotExpressed + Null + + + A*68:217 + HLA23374 + Undefined + - + + + A*68:218 + HLA23150 + Undefined + - + + + A*68:219 + HLA23138 + Undefined + - + + + A*68:220 + HLA24272 + Undefined + - + + + A*68:221 + HLA24210 + Undefined + - + + + A*68:222 + HLA24408 + Undefined + - + + + A*68:223 + HLA25301 + Undefined + - + + + A*68:224 + HLA24543 + Undefined + - + + + A*68:225 + HLA25817 + Undefined + - + + + A*68:226 + HLA25735 + Undefined + - + + + A*68:227 + HLA25886 + Undefined + - + + + A*68:228 + HLA26353 + Undefined + - + + + A*68:229 + HLA26387 + Undefined + - + + + A*68:230 + HLA26492 + Undefined + - + + + A*68:231 + HLA26395 + Undefined + - + + + A*68:232 + HLA26803 + Undefined + - + + + A*68:233 + HLA26771 + Undefined + - + + + A*68:234 + HLA26837 + Undefined + - + + + A*68:235 + HLA27003 + Undefined + - + + + A*68:236N + HLA27029 + NotExpressed + Null + + + A*68:237 + HLA27031 + Undefined + - + + + A*68:238 + HLA27033 + Undefined + - + + + A*68:239 + HLA27483 + Undefined + - + + + A*68:240 + HLA27496 + Undefined + - + + + A*68:241 + HLA27498 + Undefined + - + + + A*68:242 + HLA27331 + Undefined + - + + + A*68:243 + HLA27956 + Undefined + - + + + A*68:244:01 + HLA27978 + Undefined + - + + + A*68:244:02 + HLA29723 + Undefined + - + + + A*68:245N + HLA27982 + NotExpressed + Null + + + A*68:246 + HLA27985 + Undefined + - + + + A*68:247 + HLA27986 + Undefined + - + + + A*68:248 + HLA27991 + Undefined + - + + + A*68:249 + HLA28380 + Bw4 + Undefined + - + + + A*68:250 + HLA28640 + Undefined + - + + + A*68:251N + HLA28920 + NotExpressed + Null + + + A*68:252 + HLA29168 + Undefined + - + + + A*68:253 + HLA29668 + Undefined + - + + + A*68:254 + HLA29487 + Undefined + - + + + A*68:255 + HLA29493 + Undefined + - + + + A*68:256 + HLA29780 + Undefined + - + + + A*68:257 + HLA29753 + Undefined + - + + + A*68:258 + HLA29708 + Undefined + - + + + A*68:259 + HLA29709 + Undefined + - + + + A*68:260 + HLA30070 + Undefined + - + + + A*68:261 + HLA29939 + Undefined + - + + + A*68:262 + HLA30714 + Undefined + - + + + A*68:263Q + HLA30661 + Undefined + - + + + A*68:264 + HLA30578 + Undefined + - + + + A*68:265 + HLA30599 + Undefined + - + + + A*68:266N + HLA30845 + NotExpressed + Null + + + A*68:267N + HLA30843 + NotExpressed + Null + + + A*68:268 + HLA30818 + Undefined + - + + + A*68:269N + HLA31037 + NotExpressed + Null + + + A*68:270 + HLA31269 + Undefined + - + + + A*68:271 + HLA31367 + Undefined + - + + + A*68:272 + HLA31179 + Undefined + - + + + A*68:273 + HLA31671 + Undefined + - + + + A*68:274 + HLA31789 + Undefined + - + + + A*68:275 + HLA31719 + Undefined + - + + + A*68:276Q + HLA31882 + Undefined + - + + + A*68:277 + HLA32083 + Undefined + - + + + A*68:278 + HLA32101 + Undefined + - + + + A*68:279 + HLA32024 + Undefined + - + + + A*68:280 + HLA32560 + Undefined + - + + + A*68:281N + HLA32471 + NotExpressed + Null + + + A*68:282 + HLA32499 + Undefined + - + + + A*68:283 + HLA32505 + Undefined + - + + + A*68:284 + HLA33318 + Undefined + - + + + A*68:285 + HLA32794 + Undefined + - + + + A*68:286 + HLA34182 + Undefined + - + + + A*68:287 + HLA34408 + Undefined + - + + + A*68:288 + HLA34409 + Undefined + - + + + A*68:289 + HLA34758 + Undefined + - + + + A*68:290 + HLA34810 + Undefined + - + + + A*68:291 + HLA34697 + Undefined + - + + + A*68:292N + HLA35121 + NotExpressed + Null + + + A*68:293Q + HLA35344 + Undefined + - + + + A*68:294 + HLA35140 + Undefined + - + + + A*68:295 + HLA35591 + Undefined + - + + + A*68:296 + HLA35662 + Undefined + - + + + A*68:297 + HLA36431 + Undefined + - + + + A*68:298 + HLA36929 + Undefined + - + + + A*68:299 + HLA37049 + Undefined + - + + + A*68:300 + HLA37307 + Undefined + - + + + A*68:301 + HLA37455 + Undefined + - + + + A*68:302 + HLA37660 + Undefined + - + + + A*68:303 + HLA37704 + Undefined + - + + + A*68:304 + HLA37759 + Undefined + - + + + A*68:305 + HLA37817 + Undefined + - + + + A*68:306 + HLA38102 + Undefined + - + + + A*68:307 + HLA38493 + Undefined + - + + + A*68:308 + HLA38328 + Undefined + - + + + A*69:01:01:01 + HLA00126 + A69 + A69(28) + + + A*69:01:01:02 + HLA16440 + A69 + A69(28) + + + A*69:01:01:03 + HLA27021 + A69 + A69(28) + + + A*69:01:02 + HLA15518 + A69 + A69(28) + + + A*69:01:03 + HLA18728 + A69 + A69(28) + + + A*69:01:04 + HLA29685 + A69 + A69(28) + + + A*69:01:05 + HLA37834 + A69 + A69(28) + + + A*69:02 + HLA09785 + Undefined + - + + + A*69:03 + HLA10971 + Undefined + - + + + A*69:04 + HLA19329 + Undefined + - + + + A*69:05 + HLA20776 + Undefined + - + + + A*69:06 + HLA23561 + Undefined + - + + + A*69:07 + HLA24447 + Undefined + - + + + A*69:08 + HLA25587 + Undefined + - + + + A*69:09 + HLA34237 + Undefined + - + + + A*74:01:01:01 + HLA00127 + A74 + A74(19) + + + A*74:01:01:02 + HLA21175 + A74 + A74(19) + + + A*74:01:01:03 + HLA21542 + A74 + A74(19) + + + A*74:01:01:04 + HLA21685 + A74 + A74(19) + + + A*74:01:01:05 + HLA23707 + A74 + A74(19) + + + A*74:01:01:06 + HLA24916 + A74 + A74(19) + + + A*74:01:01:07 + HLA24526 + A74 + A74(19) + + + A*74:01:01:08 + HLA34796 + A74 + A74(19) + + + A*74:01:02 + HLA14073 + A74 + A74(19) + + + A*74:01:03 + HLA14093 + A74 + A74(19) + + + A*74:01:04 + HLA14773 + A74 + A74(19) + + + A*74:01:05 + HLA16832 + A74 + A74(19) + + + A*74:01:06 + HLA17647 + A74 + A74(19) + + + A*74:01:07 + HLA18245 + A74 + A74(19) + + + A*74:01:08 + HLA18582 + A74 + A74(19) + + + A*74:01:09 + HLA38122 + A74 + A74(19) + + + A*74:02:01:01 + HLA00128 + A74 + A74(19) + + + A*74:02:01:02 + HLA05527 + A74 + A74(19) + + + A*74:02:01:03 + HLA30457 + A74 + A74(19) + + + A*74:03:01:01 + HLA00129 + A74 + A74(19) + + + A*74:03:01:02 + HLA25681 + A74 + A74(19) + + + A*74:03:01:03 + HLA29463 + A74 + A74(19) + + + A*74:03:02 + HLA26420 + A74 + A74(19) + + + A*74:03:03 + HLA34786 + A74 + A74(19) + + + A*74:04 + HLA01115 + A74 + - + + + A*74:05 + HLA01254 + A74 + - + + + A*74:06 + HLA01422 + A74 + A74(19) + + + A*74:07 + HLA01519 + A74 + A74(19) + + + A*74:08 + HLA01544 + A74 + - + + + A*74:09 + HLA01653 + A74 + - + + + A*74:10 + HLA01819 + Undefined + - + + + A*74:11 + HLA02254 + A74 + - + + + A*74:12N + HLA02379 + NotExpressed + Null + + + A*74:13 + HLA03499 + Undefined + - + + + A*74:14N + HLA03771 + NotExpressed + Null + + + A*74:15 + HLA05967 + Undefined + - + + + A*74:16:01 + HLA08280 + Undefined + - + + + A*74:16:02 + HLA11218 + Undefined + - + + + A*74:17 + HLA08456 + Undefined + - + + + A*74:18 + HLA10117 + Undefined + - + + + A*74:19 + HLA10137 + Undefined + - + + + A*74:20 + HLA10390 + Undefined + - + + + A*74:21 + HLA10897 + Undefined + - + + + A*74:22 + HLA11315 + Undefined + - + + + A*74:23 + HLA12417 + Undefined + - + + + A*74:24 + HLA12957 + Undefined + - + + + A*74:25 + HLA13956 + Undefined + - + + + A*74:26 + HLA14131 + Undefined + - + + + A*74:27 + HLA14288 + Undefined + - + + + A*74:28 + HLA15530 + Undefined + - + + + A*74:29 + HLA19470 + Undefined + - + + + A*74:30 + HLA19311 + Undefined + - + + + A*74:31 + HLA20122 + Undefined + - + + + A*74:32N + HLA20017 + NotExpressed + Null + + + A*74:33 + HLA21376 + Undefined + - + + + A*74:34 + HLA21301 + Undefined + - + + + A*74:35 + HLA22633 + Undefined + - + + + A*74:36 + HLA23853 + Undefined + - + + + A*74:37 + HLA25579 + Undefined + - + + + A*74:38 + HLA26404 + 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HLA11435 + Bw6 + Undefined + - + + + B*07:217 + HLA11446 + Bw6 + Undefined + - + + + B*07:218 + HLA11448 + Bw6 + Undefined + - + + + B*07:219 + HLA11449 + Bw4 + Undefined + - + + + B*07:220 + HLA11719 + Bw6 + Undefined + - + + + B*07:221 + HLA11735 + Bw6 + Undefined + - + + + B*07:222 + HLA11837 + Bw6 + Undefined + - + + + B*07:223 + HLA11840 + Bw6 + Undefined + - + + + B*07:224 + HLA11948 + Bw6 + Undefined + - + + + B*07:225 + HLA12036 + Bw6 + Undefined + - + + + B*07:226 + HLA12171 + Bw6 + Undefined + - + + + B*07:227 + HLA12176 + Bw6 + Undefined + - + + + B*07:228:01 + HLA12307 + Bw6 + Undefined + - + + + B*07:228:02 + HLA16505 + Bw6 + Undefined + - + + + B*07:229:01 + HLA12308 + Bw6 + Undefined + - + + + B*07:229:02 + HLA25243 + Bw6 + Undefined + - + + + B*07:230 + HLA12311 + Bw6 + Undefined + - + + + B*07:231N + HLA12312 + NotExpressed + Null + + + B*07:232 + HLA12313 + Bw6 + Undefined + - + + + B*07:233 + HLA12486 + Bw6 + Undefined + - + + + B*07:234 + HLA12569 + Bw6 + Undefined 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B*07:256 + HLA13542 + Bw6 + Undefined + - + + + B*07:257 + HLA14235 + Bw6 + Undefined + - + + + B*07:258 + HLA14237 + Bw6 + Undefined + - + + + B*07:259 + HLA14314 + Bw6 + Undefined + - + + + B*07:260 + HLA14315 + Bw6 + Undefined + - + + + B*07:261 + HLA14402 + Bw6 + Undefined + - + + + B*07:262:01 + HLA14448 + Bw6 + Undefined + - + + + B*07:262:02 + HLA32321 + Bw6 + Undefined + - + + + B*07:263 + HLA14451 + Bw6 + Undefined + - + + + B*07:264 + HLA14455 + Bw6 + Undefined + - + + + B*07:265 + HLA14481 + Bw6 + Undefined + - + + + B*07:266 + HLA14619 + Bw6 + Undefined + - + + + B*07:267 + HLA14620 + Bw6 + Undefined + - + + + B*07:268 + HLA14735 + Bw6 + Undefined + - + + + B*07:269 + HLA14884 + Bw6 + Undefined + - + + + B*07:270 + HLA15035 + Bw6 + Undefined + - + + + B*07:271 + HLA14941 + Bw6 + Undefined + - + + + B*07:272N + HLA14973 + NotExpressed + Null + + + B*07:273 + HLA15287 + Bw4 + Undefined + - + + + B*07:274 + HLA15288 + Bw6 + Undefined + - + + + B*07:275 + HLA15291 + Bw6 + Undefined + - + + + B*07:276:01 + HLA15468 + Bw6 + Undefined + - + + + B*07:276:02 + HLA16224 + Bw6 + Undefined + - + + + B*07:277 + HLA15417 + Bw6 + Undefined + - + + + B*07:278 + HLA15640 + Bw6 + Undefined + - + + + B*07:279 + HLA15641 + Bw6 + Undefined + - + + + B*07:280 + HLA15646 + Bw6 + Undefined + - + + + B*07:281 + HLA15740 + Bw6 + Undefined + - + + + B*07:282 + HLA15577 + Bw6 + Undefined + - + + + B*07:283 + HLA15612 + Bw6 + Undefined + - + + + B*07:284 + HLA16246 + Bw6 + Undefined + - + + + B*07:285N + HLA16249 + NotExpressed + Null + + + B*07:286 + HLA16253 + Bw6 + Undefined + - + + + B*07:287 + HLA16056 + Bw6 + Undefined + - + + + B*07:288 + HLA16503 + Bw6 + Undefined + - + + + B*07:289 + HLA16504 + Bw6 + Undefined + - + + + B*07:290 + HLA16506 + Bw6 + Undefined + - + + + B*07:291 + HLA16741 + Bw6 + Undefined + - + + + B*07:292 + HLA16935 + Bw6 + Undefined + - + + + B*07:293 + HLA16937 + Bw6 + Undefined + - + + + B*07:294 + HLA17046 + Bw6 + Undefined + - + + + B*07:295 + HLA17404 + Bw6 + Undefined + - + + + B*07:296 + HLA17500 + Bw6 + Undefined + - + + + B*07:297 + HLA17567 + Bw6 + Undefined + - + + + B*07:298 + HLA17595 + Bw6 + Undefined + - + + + B*07:299 + HLA17747 + Bw6 + Undefined + - + + + B*07:300 + HLA17866 + Bw6 + Undefined + - + + + B*07:301 + HLA17867 + Bw6 + Undefined + - + + + B*07:302 + HLA17868 + Bw6 + Undefined + - + + + B*07:303:01 + HLA17869 + Bw6 + Undefined + - + + + B*07:303:02 + HLA21616 + Bw6 + Undefined + - + + + B*07:304 + HLA17765 + Bw6 + Undefined + - + + + B*07:305 + HLA17767 + Bw6 + Undefined + - + + + B*07:306 + HLA18362 + Bw6 + Undefined + - + + + B*07:307 + HLA18364 + Bw6 + Undefined + - + + + B*07:308 + HLA18409 + Bw6 + Undefined + - + + + B*07:309 + HLA18420 + Bw6 + Undefined + - + + + B*07:310 + HLA18422 + Bw6 + Undefined + - + + + B*07:311 + HLA18429 + Bw6 + Undefined + - + + + B*07:312 + HLA19095 + Bw6 + Undefined + - + + + B*07:313 + HLA19113 + Bw6 + Undefined + - + + + B*07:314 + HLA19132 + Bw6 + Undefined + - + + 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Undefined + - + + + B*35:516 + HLA30654 + Bw6 + Undefined + - + + + B*35:517 + HLA30649 + Bw6 + Undefined + - + + + B*35:518 + HLA30766 + Bw6 + Undefined + - + + + B*35:519 + HLA30862 + Bw6 + Undefined + - + + + B*35:520 + HLA31002 + Bw6 + Undefined + - + + + B*35:521 + HLA31077 + Bw6 + Undefined + - + + + B*35:522 + HLA31133 + Undefined + - + + + B*35:523 + HLA31211 + Bw6 + Undefined + - + + + B*35:524 + HLA31647 + Bw6 + Undefined + - + + + B*35:525 + HLA31659 + Undefined + - + + + B*35:526 + HLA31628 + Bw6 + Undefined + - + + + B*35:527 + HLA31652 + Bw6 + Undefined + - + + + B*35:528 + HLA31622 + Bw6 + Undefined + - + + + B*35:529 + HLA31650 + Bw6 + Undefined + - + + + B*35:530 + HLA31914 + Bw6 + Undefined + - + + + B*35:531 + HLA32015 + Bw6 + Undefined + - + + + B*35:532 + HLA31995 + Bw6 + Undefined + - + + + B*35:533 + HLA32204 + Bw6 + Undefined + - + + + B*35:534 + HLA32361 + Bw6 + Undefined + - + + + B*35:535 + HLA32366 + Bw6 + Undefined + - + + + B*35:536 + HLA32576 + Bw6 + Undefined + - + + + B*35:537 + HLA32308 + Bw6 + Undefined + - + + + B*35:538 + HLA32578 + Bw6 + Undefined + - + + + B*35:539 + HLA32579 + Bw6 + Undefined + - + + + B*35:540 + HLA32373 + Bw6 + Undefined + - + + + B*35:541 + HLA32621 + Bw6 + Undefined + - + + + B*35:542N + HLA33340 + NotExpressed + Null + + + B*35:543 + HLA33454 + Bw6 + Undefined + - + + + B*35:544 + HLA32782 + Bw6 + Undefined + - + + + B*35:545 + HLA33687 + Bw6 + Undefined + - + + + B*35:546 + HLA33555 + Bw6 + Undefined + - + + + B*35:547 + HLA33748 + Bw6 + Undefined + - + + + B*35:548 + HLA33981 + Bw6 + Undefined + - + + + B*35:549 + HLA34012 + Bw6 + Undefined + - + + + B*35:550 + HLA34241 + Undefined + - + + + B*35:551N + HLA34704 + NotExpressed + Null + + + B*35:552 + HLA34797 + Bw6 + Undefined + - + + + B*35:553 + HLA34739 + Bw6 + Undefined + - + + + B*35:554 + HLA34654 + Bw6 + Undefined + - + + + B*35:555 + HLA34665 + Bw6 + Undefined + - + + + B*35:556Q + HLA34684 + Bw6 + Undefined + - + + + B*35:557 + HLA34763 + Bw6 + Undefined + - + + + B*35:558 + HLA34724 + Bw6 + Undefined + - + + + B*35:559 + HLA35261 + Bw6 + Undefined + - + + + B*35:560 + HLA35085 + Bw6 + Undefined + - + + + B*35:561 + HLA34887 + Bw6 + Undefined + - + + + B*35:562 + HLA34848 + Bw6 + Undefined + - + + + B*35:563 + HLA35513 + Bw6 + Undefined + - + + + B*35:564 + HLA35408 + Bw6 + Undefined + - + + + B*35:565 + HLA35638 + Bw6 + Undefined + - + + + B*35:566 + HLA35852 + Bw6 + Undefined + - + + + B*35:567 + HLA36121 + Bw6 + Undefined + - + + + B*35:568 + HLA36227 + Bw6 + Undefined + - + + + B*35:569 + HLA36455 + Bw6 + Undefined + - + + + B*35:570 + HLA36486 + Undefined + - + + + B*35:571 + HLA36549 + Bw6 + Undefined + - + + + B*35:572 + HLA36776 + Bw6 + Undefined + - + + + B*35:573 + HLA36680 + Bw6 + Undefined + - + + + B*35:574N + HLA36692 + NotExpressed + Null + + + B*35:575 + HLA36880 + Bw6 + Undefined + - + + + B*35:576 + HLA37063 + Bw6 + Undefined + - + + + B*35:577 + HLA37272 + Bw6 + Undefined + - + + + B*35:578 + HLA37187 + Bw6 + Undefined + - + + + B*35:579 + HLA37576 + Bw6 + Undefined + - + + + B*35:580 + HLA37519 + Bw6 + Undefined + - + + + B*35:581 + HLA37851 + Bw6 + Undefined + - + + + B*35:582 + HLA37673 + Bw6 + Undefined + - + + + B*35:583 + HLA37804 + Bw6 + Undefined + - + + + B*35:584 + HLA37903 + Bw6 + Undefined + - + + + B*35:585 + HLA37862 + Bw6 + Undefined + - + + + B*35:586 + HLA37913 + Bw6 + Undefined + - + + + B*35:587 + HLA38062 + Bw6 + Undefined + - + + + B*35:588 + HLA38170 + Bw6 + Undefined + - + + + B*35:589 + HLA38097 + Bw6 + Undefined + - + + + B*35:590 + HLA38438 + Bw6 + Undefined + - + + + B*35:591 + HLA38711 + Bw6 + Undefined + - + + + B*37:01:01:01 + HLA00265 + Bw4 + B37 + B37 + + + B*37:01:01:02 + HLA17622 + Bw4 + B37 + B37 + + + B*37:01:01:03 + HLA19005 + Bw4 + B37 + B37 + + + B*37:01:01:04 + HLA20015 + Bw4 + B37 + B37 + + + B*37:01:01:05 + HLA22910 + Bw4 + B37 + B37 + + + B*37:01:01:06 + HLA25523 + Bw4 + B37 + B37 + + + B*37:01:01:07 + HLA24432 + Bw4 + B37 + B37 + + + B*37:01:01:08 + HLA25003 + Bw4 + B37 + B37 + + + B*37:01:01:09 + HLA25080 + Bw4 + B37 + B37 + + + B*37:01:01:10 + HLA27724 + Bw4 + B37 + B37 + + + B*37:01:01:11 + HLA27922 + Bw4 + B37 + B37 + + + B*37:01:01:12 + HLA28366 + Bw4 + B37 + B37 + + + B*37:01:01:13 + HLA29232 + Bw4 + B37 + B37 + + + B*37:01:01:14 + HLA29504 + Bw4 + B37 + B37 + + + B*37:01:01:15 + HLA30160 + Bw4 + B37 + B37 + + + B*37:01:01:16 + HLA32956 + Bw4 + B37 + B37 + + + B*37:01:01:17 + HLA33049 + Bw4 + B37 + B37 + + + B*37:01:01:18 + HLA33430 + Bw4 + B37 + B37 + + + B*37:01:01:19 + HLA34515 + Bw4 + B37 + B37 + + + B*37:01:01:20 + HLA38350 + Bw4 + B37 + B37 + + + B*37:01:01:21 + HLA38334 + Bw4 + B37 + B37 + + + B*37:01:01:22 + HLA38203 + Bw4 + B37 + B37 + + + B*37:01:02 + HLA02418 + Bw4 + B37 + B37 + + + B*37:01:03 + HLA02505 + Bw4 + B37 + B37 + + + B*37:01:04 + HLA02687 + Bw4 + B37 + B37 + + + B*37:01:05 + HLA03651 + Bw4 + B37 + B37 + + + B*37:01:06 + HLA03908 + Bw4 + B37 + B37 + + + B*37:01:07 + HLA04184 + Bw4 + B37 + B37 + + + B*37:01:08 + HLA06994 + Bw4 + B37 + B37 + + + B*37:01:09 + HLA08333 + Bw4 + B37 + B37 + + + B*37:01:10 + HLA13351 + Bw4 + B37 + B37 + + + B*37:01:11 + HLA13467 + Bw4 + B37 + B37 + + + B*37:01:12 + HLA18244 + Bw4 + B37 + B37 + + + B*37:01:13 + HLA19006 + Bw4 + B37 + B37 + + + B*37:01:14 + HLA19537 + Bw4 + B37 + B37 + + + B*37:01:15 + HLA21573 + Bw4 + B37 + B37 + + + B*37:01:16 + HLA21955 + Bw4 + B37 + B37 + + + B*37:01:17 + HLA23577 + Bw4 + B37 + B37 + + + B*37:01:18 + HLA23513 + Bw4 + B37 + B37 + + + B*37:01:19 + HLA24342 + Bw4 + B37 + B37 + + + B*37:01:20 + HLA24216 + Bw4 + B37 + B37 + + + B*37:01:21 + HLA25714 + Bw4 + B37 + B37 + + + B*37:01:22 + HLA25889 + Bw4 + B37 + B37 + + + B*37:01:23 + HLA28886 + Bw4 + B37 + B37 + + + B*37:01:24 + HLA29105 + Bw4 + B37 + B37 + + + B*37:01:25 + HLA29239 + Bw4 + B37 + B37 + + + B*37:01:26 + HLA29592 + Bw4 + B37 + B37 + + + B*37:01:27 + HLA31456 + Bw4 + B37 + B37 + + + B*37:01:28 + HLA32341 + Bw4 + B37 + B37 + + + B*37:01:29 + HLA34729 + Bw4 + B37 + B37 + + + B*37:01:30 + HLA37051 + Bw4 + B37 + B37 + + + B*37:01:31 + HLA37246 + Bw4 + B37 + B37 + + + B*37:02 + HLA00266 + Bw4 + B37/27 + - + + + B*37:03N + HLA01267 + NotExpressed + Null + + + B*37:04:01 + HLA01346 + Bw4 + B37 + B37 + + + B*37:04:02 + HLA04738 + Bw4 + B37 + B37 + + + B*37:05 + HLA01359 + Blank + - + + + B*37:06:01 + HLA01949 + Bw4 + B37 + - + + + B*37:06:02 + HLA10534 + Bw4 + B37 + - + + + B*37:07 + HLA02007 + Bw4 + Undefined + - + + + B*37:08 + HLA02015 + Bw4 + B37 + B37 + + + B*37:09 + HLA02149 + Bw4 + B37 + B37 + + + B*37:10 + HLA02231 + Bw4 + B37 + B37 + + + B*37:11 + HLA02479 + Bw6 + Undefined + - + + + B*37:12 + HLA02532 + Bw4 + B37 + - + + + B*37:13 + HLA02874 + Bw4 + B37 + - + + + B*37:14 + HLA03350 + Undefined + - + + + B*37:15 + HLA03959 + Bw4 + Undefined + - + + + B*37:16Q + HLA04073 + Bw4 + Undefined + - + + + B*37:17 + HLA04208 + Bw4 + Undefined + - + + + B*37:18 + HLA04229 + Bw4 + Undefined + - + + + B*37:19:01 + HLA04160 + Bw4 + Undefined + - + + + B*37:19:02 + HLA13967 + Bw4 + Undefined + - + + + B*37:20 + HLA04511 + Bw4 + Undefined + - + + + B*37:21 + HLA04539 + Bw4 + Undefined + - + + + B*37:22:01 + HLA04692 + Bw4 + Undefined + - + + + B*37:22:02 + HLA27514 + Bw4 + Undefined + - + + + B*37:22:03 + HLA32008 + Bw4 + Undefined + - + + + B*37:23 + HLA05421 + Bw4 + Undefined + - + + + B*37:24 + HLA05487 + Bw4 + Undefined + - + + + B*37:25 + HLA05719 + Bw4 + Undefined + - + + + B*37:26 + HLA06182 + Bw4 + Undefined + - + + + B*37:27 + HLA06231 + Bw4 + Undefined + - + + + B*37:28 + HLA06257 + Bw4 + Undefined + - + + + B*37:29 + HLA06321 + Bw4 + Undefined + - + + + B*37:30N + HLA06916 + NotExpressed + Null + + + B*37:31 + HLA06941 + Bw4 + Undefined + - + + + B*37:32 + HLA07552 + Bw4 + Undefined + - + + + B*37:33N + HLA07690 + NotExpressed + Null + + + B*37:34 + HLA07931 + Bw4 + Undefined + - + + + B*37:35 + HLA08334 + Bw4 + Undefined + - + + + B*37:36 + HLA08337 + Bw4 + Undefined + - + + + B*37:37 + HLA08779 + Bw6 + Undefined + 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C*01:02:01:58 + HLA33164 + Cw1 + Cw1 + + + C*01:02:01:59 + HLA33006 + Cw1 + Cw1 + + + C*01:02:01:60 + HLA33408 + Cw1 + Cw1 + + + C*01:02:01:61 + HLA32800 + Cw1 + Cw1 + + + C*01:02:01:62 + HLA33235 + Cw1 + Cw1 + + + C*01:02:01:63 + HLA32757 + Cw1 + Cw1 + + + C*01:02:01:64 + HLA32854 + Cw1 + Cw1 + + + C*01:02:01:65 + HLA33546 + Cw1 + Cw1 + + + C*01:02:01:66 + HLA34575 + Cw1 + Cw1 + + + C*01:02:01:67 + HLA35355 + Cw1 + Cw1 + + + C*01:02:01:68 + HLA34869 + Cw1 + Cw1 + + + C*01:02:01:69 + HLA37497 + Cw1 + Cw1 + + + C*01:02:01:70 + HLA37699 + Cw1 + Cw1 + + + C*01:02:01:71 + HLA38238 + Cw1 + Cw1 + + + C*01:02:01:72 + HLA38104 + Cw1 + Cw1 + + + C*01:02:02 + HLA01798 + Cw1 + Cw1 + + + C*01:02:03 + HLA02044 + Cw1 + Cw1 + + + C*01:02:04 + HLA02670 + Cw1 + Cw1 + + + C*01:02:05 + HLA02815 + Cw1 + Cw1 + + + C*01:02:06 + HLA03445 + Cw1 + Cw1 + + + C*01:02:07 + HLA03730 + Cw1 + Cw1 + + + C*01:02:08 + HLA04275 + Cw1 + Cw1 + + + C*01:02:09 + HLA04606 + Cw1 + Cw1 + + + C*01:02:10 + HLA05209 + Cw1 + Cw1 + 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Cw1 + + + C*01:02:35 + HLA12765 + Cw1 + Cw1 + + + C*01:02:36 + HLA13526 + Cw1 + Cw1 + + + C*01:02:37 + HLA14597 + Cw1 + Cw1 + + + C*01:02:38 + HLA14643 + Cw1 + Cw1 + + + C*01:02:39 + HLA15111 + Cw1 + Cw1 + + + C*01:02:40 + HLA15195 + Cw1 + Cw1 + + + C*01:02:41 + HLA15929 + Cw1 + Cw1 + + + C*01:02:42 + HLA17414 + Cw1 + Cw1 + + + C*01:02:43 + HLA17649 + Cw1 + Cw1 + + + C*01:02:44 + HLA18396 + Cw1 + Cw1 + + + C*01:02:45 + HLA18486 + Cw1 + Cw1 + + + C*01:02:46 + HLA19414 + Cw1 + Cw1 + + + C*01:02:47 + HLA20266 + Cw1 + Cw1 + + + C*01:02:48 + HLA20027 + Cw1 + Cw1 + + + C*01:02:49 + HLA20898 + Cw1 + Cw1 + + + C*01:02:50 + HLA21099 + Cw1 + Cw1 + + + C*01:02:51 + HLA20802 + Cw1 + Cw1 + + + C*01:02:52 + HLA21229 + Cw1 + Cw1 + + + C*01:02:53 + HLA21717 + Cw1 + Cw1 + + + C*01:02:54 + HLA21855 + Cw1 + Cw1 + + + C*01:02:55 + HLA21629 + Cw1 + Cw1 + + + C*01:02:56 + HLA23005 + Cw1 + Cw1 + + + C*01:02:57 + HLA23004 + Cw1 + Cw1 + + + C*01:02:58 + HLA23243 + Cw1 + Cw1 + + + C*01:02:59 + HLA23637 + Cw1 + Cw1 + + + C*01:02:60 + HLA23071 + Cw1 + Cw1 + + + C*01:02:61 + HLA23842 + Cw1 + Cw1 + + + C*01:02:62 + HLA24300 + Cw1 + Cw1 + + + C*01:02:63 + HLA24285 + Cw1 + Cw1 + + + C*01:02:64 + HLA26068 + Cw1 + Cw1 + + + C*01:02:65 + HLA26667 + Cw1 + Cw1 + + + C*01:02:66 + HLA27594 + Cw1 + Cw1 + + + C*01:02:67 + HLA27856 + Cw1 + Cw1 + + + C*01:02:68 + HLA28130 + Cw1 + Cw1 + + + C*01:02:69 + HLA28271 + Cw1 + Cw1 + + + C*01:02:70 + HLA28290 + Cw1 + Cw1 + + + C*01:02:71 + HLA28299 + Cw1 + Cw1 + + + C*01:02:72 + HLA28503 + Cw1 + Cw1 + + + C*01:02:73 + HLA29255 + Cw1 + Cw1 + + + C*01:02:74 + HLA29652 + Cw1 + Cw1 + + + C*01:02:75 + HLA29810 + Cw1 + Cw1 + + + C*01:02:76 + HLA30470 + Cw1 + Cw1 + + + C*01:02:77 + HLA30948 + Cw1 + Cw1 + + + C*01:02:78 + HLA31256 + Cw1 + Cw1 + + + C*01:02:79 + HLA31070 + Cw1 + Cw1 + + + C*01:02:80 + HLA31561 + Cw1 + Cw1 + + + C*01:02:81 + HLA33493 + Cw1 + Cw1 + + + C*01:02:82 + HLA34205 + Cw1 + Cw1 + + + C*01:02:83 + HLA34101 + Cw1 + Cw1 + + + C*01:02:84 + HLA34795 + Cw1 + Cw1 + + + C*01:02:85 + HLA34850 + Cw1 + Cw1 + + + C*01:02:86 + HLA35130 + Cw1 + Cw1 + + + C*01:02:87 + HLA35377 + Cw1 + Cw1 + + + C*01:02:88 + HLA35682 + Cw1 + Cw1 + + + C*01:02:89 + HLA36012 + Cw1 + Cw1 + + + C*01:02:90 + HLA36809 + Cw1 + Cw1 + + + C*01:02:91 + HLA37201 + Cw1 + Cw1 + + + C*01:02:92 + HLA37277 + Cw1 + Cw1 + + + C*01:03:01 + HLA00402 + Cw1 + Cw1 + + + C*01:03:02 + HLA28176 + Cw1 + Cw1 + + + C*01:03:03 + HLA34394 + Cw1 + Cw1 + + + C*01:04 + HLA01075 + Cw1 + - + + + C*01:05 + HLA01434 + Cw1 + - + + + C*01:06 + HLA01555 + Cw1 + - + + + C*01:07:01 + HLA01644 + Cw1/blank + - + + + C*01:07:02 + HLA12493 + Cw1/blank + - + + + C*01:08 + HLA01636 + Cw1 + - + + + C*01:09:01 + HLA01659 + Cw1 + Cw1 + + + C*01:09:02 + HLA24265 + Cw1 + Cw1 + + + C*01:10 + HLA01866 + Cw1 + - + + + C*01:11 + HLA02123 + Cw1 + - + + + C*01:12:01 + HLA02469 + Cw1 + - + + + C*01:12:02 + HLA10567 + Cw1 + - + + + C*01:13 + HLA02478 + Cw1 + - + + + C*01:14 + HLA02790 + Cw1 + - + + + C*01:15:01 + HLA02811 + Cw1 + - + + + C*01:15:02 + HLA17321 + Cw1 + - + + + C*01:16 + HLA02812 + Cw1 + - + + + C*01:17 + HLA02813 + Cw1 + - + + + C*01:18 + HLA02814 + Cw1 + - + + + C*01:19 + HLA02947 + Cw1 + - + + + C*01:20 + HLA03233 + Undefined + - + + + C*01:21 + HLA03303 + Undefined + - + + + C*01:22 + HLA03363 + Undefined + - + + + C*01:23 + HLA03598 + Undefined + - + + + C*01:24 + HLA03636 + Undefined + - + + + C*01:25 + HLA03650 + Undefined + - + + + C*01:26 + HLA03706 + Undefined + - + + + C*01:27 + HLA03707 + Undefined + - + + + C*01:28 + HLA03830 + Undefined + - + + + C*01:29 + HLA04019 + Undefined + - + + + C*01:30 + HLA04020 + Undefined + - + + + C*01:31 + HLA04258 + Undefined + - + + + C*01:32:01 + HLA04289 + Undefined + - + + + C*01:32:02 + HLA15163 + Undefined + - + + + C*01:33 + HLA04290 + Undefined + - + + + C*01:34 + HLA04570 + Undefined + - + + + C*01:35 + HLA04731 + Undefined + - + + + C*01:36:01 + HLA04756 + Undefined + - + + + C*01:36:02 + HLA26217 + Undefined + - + + + C*01:37N + 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C*02:55:02 + HLA14029 + Undefined + - + + + C*02:56 + HLA07493 + Undefined + - + + + C*02:57 + HLA07944 + Undefined + - + + + C*02:58 + HLA07965 + Undefined + - + + + C*02:59 + HLA08118 + Undefined + - + + + C*02:60 + HLA08209 + Undefined + - + + + C*02:61:01 + HLA08211 + Undefined + - + + + C*02:61:02 + HLA27168 + Undefined + - + + + C*02:62 + HLA08212 + Undefined + - + + + C*02:63 + HLA08213 + Undefined + - + + + C*02:64 + HLA08533 + Undefined + - + + + C*02:65 + HLA08755 + Undefined + - + + + C*02:66 + HLA08756 + Undefined + - + + + C*02:67Q + HLA09035 + Undefined + - + + + C*02:68 + HLA09616 + Undefined + - + + + C*02:69 + HLA09921 + Undefined + - + + + C*02:70 + HLA09940 + Undefined + - + + + C*02:71 + HLA09961 + Undefined + - + + + C*02:72 + HLA09963 + Undefined + - + + + C*02:73 + HLA10438 + Undefined + - + + + C*02:74 + HLA10439 + Undefined + - + + + C*02:75 + HLA11106 + Undefined + - + + + C*02:76 + HLA11107 + Undefined + - + + + C*02:77 + HLA11108 + Undefined + - + + + C*02:78 + HLA11109 + Undefined + - + + + C*02:79 + HLA11110 + Undefined + - + + + C*02:80 + HLA11122 + Undefined + - + + + C*02:81 + HLA11260 + Undefined + - + + + C*02:82 + HLA11664 + Undefined + - + + + C*02:83 + HLA11764 + Undefined + - + + + C*02:84 + HLA11868 + Undefined + - + + + C*02:85 + HLA12093 + Undefined + - + + + C*02:86 + HLA12095 + Undefined + - + + + C*02:87 + HLA12186 + Undefined + - + + + C*02:88 + HLA12194 + Undefined + - + + + C*02:89 + HLA12418 + Undefined + - + + + C*02:90 + HLA12652 + Undefined + - + + + C*02:91 + HLA12708 + Undefined + - + + + C*02:92N + HLA12731 + NotExpressed + Null + + + C*02:93 + HLA12779 + Undefined + - + + + C*02:94 + HLA12778 + Undefined + - + + + C*02:95 + HLA12780 + Undefined + - + + + C*02:96 + HLA13109 + Undefined + - + + + C*02:97 + HLA13110 + Undefined + - + + + C*02:98 + HLA13111 + Undefined + - + + + C*02:99 + HLA13112 + Undefined + - + + + C*02:100 + HLA13113 + Undefined + - + + + C*02:101 + HLA13370 + Undefined + - + + + C*02:102 + HLA13512 + Undefined + - + + + C*02:103 + HLA13519 + Undefined + - + + + C*02:104 + HLA13568 + Undefined + - + + + C*02:105N + HLA13503 + NotExpressed + Null + + + C*02:106 + HLA13627 + Undefined + - + + + C*02:107 + HLA13867 + Undefined + - + + + C*02:108 + HLA13875 + Undefined + - + + + C*02:109 + HLA14335 + Undefined + - + + + C*02:110 + HLA14535 + Undefined + - + + + C*02:111 + HLA14536 + Undefined + - + + + C*02:112 + HLA14538 + Undefined + - + + + C*02:113 + HLA14752 + Undefined + - + + + C*02:114 + HLA14753 + Undefined + - + + + C*02:115 + HLA14865 + Undefined + - + + + C*02:116 + HLA15055 + Undefined + - + + + C*02:117 + HLA15056 + Undefined + - + + + C*02:118 + HLA15119 + Undefined + - + + + C*02:119 + HLA15309 + Undefined + - + + + C*02:120 + HLA15179 + Undefined + - + + + C*02:121N + HLA15745 + NotExpressed + Null + + + C*02:122 + HLA15793 + Undefined + - + + + C*02:123 + HLA15810 + Undefined + - + + + C*02:124 + HLA15930 + Undefined + - + + + C*02:125 + HLA15981 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C*02:149 + HLA20146 + Undefined + - + + + C*02:150N + HLA19960 + NotExpressed + Null + + + C*02:151 + HLA20125 + Undefined + - + + + C*02:152 + HLA20422 + Undefined + - + + + C*02:153 + HLA20402 + Undefined + - + + + C*02:154 + HLA20322 + Undefined + - + + + C*02:155 + HLA20077 + Undefined + - + + + C*02:156 + HLA20350 + Undefined + - + + + C*02:157 + HLA21086 + Undefined + - + + + C*02:158 + HLA20788 + Undefined + - + + + C*02:159 + HLA21123 + Undefined + - + + + C*02:160 + HLA21090 + Undefined + - + + + C*02:161 + HLA21048 + Undefined + - + + + C*02:162 + HLA20711 + Undefined + - + + + C*02:163 + HLA21480 + Undefined + - + + + C*02:164 + HLA21601 + Undefined + - + + + C*02:165N + HLA21622 + NotExpressed + Null + + + C*02:166 + HLA21873 + Undefined + - + + + C*02:167 + HLA22713 + Undefined + - + + + C*02:168 + HLA22661 + Undefined + - + + + C*02:169N + HLA22710 + NotExpressed + Null + + + C*02:170 + HLA23594 + Undefined + - + + + C*02:171 + HLA23779 + Undefined + - + + + C*02:172 + HLA23749 + Undefined + - + + + C*02:173 + HLA23862 + Undefined + - + + + C*02:174 + HLA24202 + Undefined + - + + + C*02:175 + HLA23883 + Undefined + - + + + C*02:176 + HLA24313 + Undefined + - + + + C*02:177 + HLA23831 + Undefined + - + + + C*02:178 + HLA24094 + Undefined + - + + + C*02:179 + HLA24135 + Undefined + - + + + C*02:180 + HLA25223 + Undefined + - + + + C*02:181 + HLA24450 + Undefined + - + + + C*02:182 + HLA25034 + Undefined + - + + + C*02:183 + HLA25685 + Undefined + - + + + C*02:184 + HLA25875 + Undefined + - + + + C*02:185 + HLA25967 + Undefined + - + + + C*02:186 + HLA26172 + Undefined + - + + + C*02:187 + HLA26316 + Undefined + - + + + C*02:188 + HLA27111 + Undefined + - + + + C*02:189 + HLA26947 + Undefined + - + + + C*02:190 + HLA27584 + Undefined + - + + + C*02:191 + HLA27806 + Undefined + - + + + C*02:192N + HLA28155 + NotExpressed + Null + + + C*02:193N + HLA28679 + NotExpressed + Null + + + C*02:194 + HLA28677 + Undefined + - + + + C*02:195 + HLA28834 + Undefined 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C*02:219 + HLA37260 + Undefined + - + + + C*02:220 + HLA37321 + Undefined + - + + + C*02:221 + HLA37394 + Undefined + - + + + C*02:222 + HLA37730 + Undefined + - + + + C*02:223N + HLA37709 + NotExpressed + Null + + + C*02:224 + HLA38522 + Undefined + - + + + C*03:02:01 + HLA00410 + Cw10 + Cw10(w3) + + + C*03:02:02:01 + HLA01543 + Cw10 + Cw10(w3) + + + C*03:02:02:02 + HLA05731 + Cw10 + Cw10(w3) + + + C*03:02:02:03 + HLA09569 + Cw10 + Cw10(w3) + + + C*03:02:02:04 + HLA17617 + Cw10 + Cw10(w3) + + + C*03:02:02:05 + HLA20143 + Cw10 + Cw10(w3) + + + C*03:02:02:06 + HLA25161 + Cw10 + Cw10(w3) + + + C*03:02:02:07 + HLA25270 + Cw10 + Cw10(w3) + + + C*03:02:02:08 + HLA27581 + Cw10 + Cw10(w3) + + + C*03:02:02:09 + HLA28139 + Cw10 + Cw10(w3) + + + C*03:02:02:10 + HLA29410 + Cw10 + Cw10(w3) + + + C*03:02:02:11 + HLA29442 + Cw10 + Cw10(w3) + + + C*03:02:02:12 + HLA29571 + Cw10 + Cw10(w3) + + + C*03:02:02:13 + HLA33208 + Cw10 + Cw10(w3) + + + C*03:02:02:14 + HLA33316 + Cw10 + Cw10(w3) + + + C*03:02:02:15 + HLA33666 + Cw10 + Cw10(w3) + + + C*03:02:02:16 + HLA33708 + Cw10 + Cw10(w3) + + + C*03:02:02:17 + HLA37516 + Cw10 + Cw10(w3) + + + C*03:02:03 + HLA02800 + Cw10 + Cw10(w3) + + + C*03:02:04 + HLA04285 + Cw10 + Cw10(w3) + + + C*03:02:05 + HLA04287 + Cw10 + Cw10(w3) + + + C*03:02:06 + HLA04605 + Cw10 + Cw10(w3) + + + C*03:02:07 + HLA06126 + Cw10 + Cw10(w3) + + + C*03:02:08 + HLA06420 + Cw10 + Cw10(w3) + + + C*03:02:09 + HLA07730 + Cw10 + Cw10(w3) + + + C*03:02:10 + HLA09615 + Cw10 + Cw10(w3) + + + C*03:02:11 + HLA10103 + Cw10 + Cw10(w3) + + + C*03:02:12 + HLA10572 + Cw10 + Cw10(w3) + + + C*03:02:13 + HLA11874 + Cw10 + Cw10(w3) + + + C*03:02:14 + HLA13265 + Cw10 + Cw10(w3) + + + C*03:02:15 + HLA15212 + Cw10 + Cw10(w3) + + + C*03:02:16 + HLA17447 + Cw10 + Cw10(w3) + + + C*03:02:17 + HLA17571 + Cw10 + Cw10(w3) + + + C*03:02:18 + HLA18968 + Cw10 + Cw10(w3) + + + C*03:02:19 + HLA19973 + Cw10 + Cw10(w3) + + + C*03:02:20 + HLA21115 + Cw10 + Cw10(w3) + + + C*03:02:21 + HLA20738 + Cw10 + Cw10(w3) + + + C*03:02:22 + HLA20636 + Cw10 + Cw10(w3) + + + C*03:02:23 + HLA26261 + Cw10 + Cw10(w3) + + + C*03:02:24 + HLA28175 + Cw10 + Cw10(w3) + + + C*03:02:25 + HLA28296 + Cw10 + Cw10(w3) + + + C*03:02:26 + HLA31129 + Cw10 + Cw10(w3) + + + C*03:02:27 + HLA34227 + Cw10 + Cw10(w3) + + + C*03:02:28 + HLA35550 + Cw10 + Cw10(w3) + + + C*03:02:29 + HLA36957 + Cw10 + Cw10(w3) + + + C*03:02:30 + HLA37838 + Cw10 + Cw10(w3) + + + C*03:02:31 + HLA38729 + Cw10 + Cw10(w3) + + + C*03:03:01:01 + HLA00411 + Cw9 + Cw9(w3) + + + C*03:03:01:02 + HLA15206 + Cw9 + Cw9(w3) + + + C*03:03:01:03 + HLA16704 + Cw9 + Cw9(w3) + + + C*03:03:01:04 + HLA16705 + Cw9 + Cw9(w3) + + + C*03:03:01:05 + HLA16706 + Cw9 + Cw9(w3) + + + C*03:03:01:06 + HLA16707 + Cw9 + Cw9(w3) + + + C*03:03:01:07 + HLA16867 + Cw9 + Cw9(w3) + + + C*03:03:01:08 + HLA17300 + Cw9 + Cw9(w3) + + + C*03:03:01:09 + HLA17350 + Cw9 + Cw9(w3) + + + C*03:03:01:10 + HLA18255 + Cw9 + Cw9(w3) + + + C*03:03:01:11 + HLA19307 + Cw9 + Cw9(w3) + + + C*03:03:01:12 + HLA19430 + Cw9 + Cw9(w3) + + + C*03:03:01:13 + HLA20172 + Cw9 + Cw9(w3) + + + C*03:03:01:14 + HLA21612 + Cw9 + Cw9(w3) + + + C*03:03:01:15 + HLA24803 + Cw9 + Cw9(w3) + + + C*03:03:01:16 + HLA24851 + Cw9 + Cw9(w3) + + + C*03:03:01:17 + HLA25336 + Cw9 + Cw9(w3) + + + C*03:03:01:18 + HLA24974 + Cw9 + Cw9(w3) + + + C*03:03:01:19 + HLA25537 + Cw9 + Cw9(w3) + + + C*03:03:01:20 + HLA25203 + Cw9 + Cw9(w3) + + + C*03:03:01:21 + HLA24878 + Cw9 + Cw9(w3) + + + C*03:03:01:22 + HLA24828 + Cw9 + Cw9(w3) + + + C*03:03:01:23 + HLA25087 + Cw9 + Cw9(w3) + + + C*03:03:01:24 + HLA25673 + Cw9 + Cw9(w3) + + + C*03:03:01:25 + HLA25722 + Cw9 + Cw9(w3) + + + C*03:03:01:26 + HLA26004 + Cw9 + Cw9(w3) + + + C*03:03:01:27 + HLA26773 + Cw9 + Cw9(w3) + + + C*03:03:01:28 + HLA27130 + Cw9 + Cw9(w3) + + + C*03:03:01:29 + HLA27160 + Cw9 + Cw9(w3) + + + C*03:03:01:30 + HLA26959 + Cw9 + Cw9(w3) + + + C*03:03:01:31 + HLA27250 + Cw9 + Cw9(w3) + + + C*03:03:01:32 + HLA27616 + Cw9 + Cw9(w3) + + + C*03:03:01:33 + HLA27582 + Cw9 + Cw9(w3) + + + C*03:03:01:34 + HLA27597 + Cw9 + Cw9(w3) + + + C*03:03:01:35 + HLA27836 + Cw9 + Cw9(w3) + + + C*03:03:01:36 + HLA27906 + Cw9 + Cw9(w3) + + + C*03:03:01:37 + HLA27914 + Cw9 + Cw9(w3) + + + C*03:03:01:38 + HLA27917 + Cw9 + Cw9(w3) + + + C*03:03:01:39Q + HLA28166 + Undefined + - + + + C*03:03:01:40 + HLA29028 + Cw9 + Cw9(w3) + + + C*03:03:01:41 + HLA29259 + Cw9 + Cw9(w3) + + + C*03:03:01:42 + HLA29560 + Cw9 + Cw9(w3) + + + C*03:03:01:43 + HLA29360 + Cw9 + Cw9(w3) + + + C*03:03:01:44 + HLA30145 + Cw9 + Cw9(w3) + + + C*03:03:01:45 + HLA30287 + Cw9 + Cw9(w3) + + + C*03:03:01:46 + HLA30241 + Cw9 + Cw9(w3) + + + C*03:03:01:47 + HLA30150 + Cw9 + Cw9(w3) + + + C*03:03:01:48 + HLA30293 + Cw9 + Cw9(w3) + + + C*03:03:01:49 + HLA29946 + Cw9 + Cw9(w3) + + + C*03:03:01:50N + HLA30032 + NotExpressed + Null + + + C*03:03:01:51 + HLA29963 + Cw9 + Cw9(w3) + + + C*03:03:01:52N + HLA30763 + NotExpressed + Null + + + C*03:03:01:53 + HLA31965 + Cw9 + Cw9(w3) + + + C*03:03:01:54 + HLA32218 + Cw9 + Cw9(w3) + + + C*03:03:01:55Q + HLA32615 + Undefined + - + + + C*03:03:01:56 + HLA32954 + Cw9 + Cw9(w3) + + + C*03:03:01:57 + HLA32753 + Cw9 + Cw9(w3) + + + C*03:03:01:58 + HLA33399 + Cw9 + Cw9(w3) + + + C*03:03:01:59 + HLA33338 + Cw9 + Cw9(w3) + + + C*03:03:01:60 + HLA33488 + Cw9 + Cw9(w3) + + + C*03:03:01:61 + HLA33140 + Cw9 + Cw9(w3) + + + C*03:03:01:62 + HLA33184 + Cw9 + Cw9(w3) + + + C*03:03:01:63 + HLA33256 + Cw9 + Cw9(w3) + + + C*03:03:01:64 + HLA32835 + Cw9 + Cw9(w3) + + + C*03:03:01:65 + HLA35159 + Cw9 + Cw9(w3) + + + C*03:03:01:66 + HLA36920 + Cw9 + Cw9(w3) + + + C*03:03:01:67 + HLA36943 + Cw9 + Cw9(w3) + + + C*03:03:01:68 + HLA37919 + Cw9 + Cw9(w3) + + + C*03:03:01:69 + HLA38298 + Cw9 + Cw9(w3) + + + C*03:03:01:70 + HLA38227 + Cw9 + Cw9(w3) + + + C*03:03:02 + HLA00412 + Cw9 + Cw9(w3) + + + C*03:03:03 + HLA01355 + Cw9 + Cw9(w3) + + + C*03:03:04 + HLA01855 + Cw9 + Cw9(w3) + + + C*03:03:05 + HLA02567 + Cw9 + Cw9(w3) + + + C*03:03:06 + HLA03732 + Cw9 + Cw9(w3) + + + C*03:03:07 + HLA04264 + Cw9 + Cw9(w3) + + + C*03:03:08 + HLA04265 + Cw9 + Cw9(w3) + + + C*03:03:09 + HLA04270 + Cw9 + Cw9(w3) + + + C*03:03:10 + HLA04281 + Cw9 + Cw9(w3) + + + C*03:03:11 + HLA04288 + Cw9 + Cw9(w3) + + + C*03:03:12 + HLA05215 + Cw9 + Cw9(w3) + + + C*03:03:13 + HLA05607 + Cw9 + Cw9(w3) + + + C*03:03:14 + HLA06418 + Cw9 + Cw9(w3) + + + C*03:03:15 + HLA07024 + Cw9 + Cw9(w3) + + + C*03:03:16 + HLA07025 + Cw9 + Cw9(w3) + + + C*03:03:17 + HLA07377 + Cw9 + Cw9(w3) + + + C*03:03:18 + HLA07416 + Cw9 + Cw9(w3) + + + C*03:03:19 + HLA07954 + Cw9 + Cw9(w3) + + + C*03:03:20 + HLA09199 + Cw9 + Cw9(w3) + + + C*03:03:21 + HLA09726 + Cw9 + Cw9(w3) + + + C*03:03:22 + HLA09956 + Cw9 + Cw9(w3) + + + C*03:03:23 + HLA10579 + Cw9 + Cw9(w3) + + + C*03:03:24 + HLA10587 + Cw9 + Cw9(w3) + + + C*03:03:25 + HLA11115 + Cw9 + Cw9(w3) + + + C*03:03:26 + HLA11262 + Cw9 + Cw9(w3) + + + C*03:03:27 + HLA12510 + Cw9 + Cw9(w3) + + + C*03:03:28 + HLA12716 + Cw9 + Cw9(w3) + + + C*03:03:29 + HLA13263 + Cw9 + Cw9(w3) + + + C*03:03:30 + HLA14605 + Cw9 + Cw9(w3) + + + C*03:03:31 + HLA14681 + Cw9 + Cw9(w3) + + + C*03:03:32 + HLA15216 + Cw9 + Cw9(w3) + + + C*03:03:33 + HLA15914 + Cw9 + Cw9(w3) + + + C*03:03:34 + HLA15924 + Cw9 + Cw9(w3) + + + C*03:03:35 + HLA17281 + Cw9 + Cw9(w3) + + + C*03:03:36 + HLA17415 + Cw9 + Cw9(w3) + + + C*03:03:37 + HLA17641 + Cw9 + Cw9(w3) + + + C*03:03:38 + HLA18517 + Cw9 + Cw9(w3) + + + C*03:03:39 + HLA18489 + Cw9 + Cw9(w3) + + + C*03:03:40 + HLA18521 + Cw9 + Cw9(w3) + + + C*03:03:41 + HLA18749 + Cw9 + Cw9(w3) + + + C*03:03:42 + HLA18832 + Cw9 + Cw9(w3) + + + C*03:03:43 + HLA19106 + Cw9 + Cw9(w3) + + + C*03:03:44 + HLA19514 + Cw9 + Cw9(w3) + + + C*03:03:45 + HLA19626 + Cw9 + Cw9(w3) + + + C*03:03:46 + HLA19654 + Cw9 + Cw9(w3) + + + C*03:03:47 + HLA19770 + Cw9 + Cw9(w3) + + + C*03:03:48 + HLA19602 + Cw9 + Cw9(w3) + + + C*03:03:49 + HLA21116 + Cw9 + Cw9(w3) + + + C*03:03:50 + HLA20784 + Cw9 + Cw9(w3) + + + C*03:03:51 + HLA20657 + Cw9 + Cw9(w3) + + + 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C*03:18:02 + HLA11117 + Cw9 + - + + + C*03:18:03 + HLA19719 + Cw9 + - + + + C*03:19 + HLA02133 + Cw3 + Cw3 + + + C*03:20N + HLA02346 + NotExpressed + Null + + + C*03:21 + HLA02391 + Cw9 + - + + + C*03:22Q + HLA02414 + Undefined + - + + + C*03:23N + HLA02444 + Cw10 + - + + + C*03:24 + HLA02467 + Cw10 + Cw3 + + + C*03:25 + HLA02485 + Cw10 + - + + + C*03:26:01 + HLA02526 + Cw10 + Cw10(w3) + + + C*03:26:02 + HLA20986 + Cw10 + Cw10(w3) + + + C*03:27 + HLA02594 + Cw10 + - + + + C*03:28 + HLA02599 + Cw10 + Cw10(w3) + + + C*03:29 + HLA02600 + Cw10 + - + + + C*03:30 + HLA02617 + Cw9 + - + + + C*03:31 + HLA02648 + Cw9 + - + + + C*03:32:01:01 + HLA02681 + Cw10 + - + + + C*03:32:01:02 + HLA31945 + Cw10 + - + + + C*03:33 + HLA02715 + Cw10 + - + + + C*03:34 + HLA02729 + Cw10 + - + + + C*03:35:01 + HLA02758 + Cw10 + - + + + C*03:35:02:01 + HLA15901 + Cw10 + - + + + C*03:35:02:02 + HLA21063 + Cw10 + - + + + C*03:36 + HLA02817 + Cw10 + - + + + C*03:37:01 + HLA02818 + Cw10 + - + + + C*03:37:02 + HLA08536 + Cw10 + - + + + C*03:38:01 + HLA02821 + Cw10 + - + + + C*03:38:02 + HLA03048 + Cw10 + - + + + C*03:39 + HLA02843 + Cw9 + Cw3 + + + C*03:40:01 + HLA02881 + Cw10 + Cw3 + + + C*03:40:02 + HLA07015 + Cw10 + Cw3 + + + C*03:40:03 + HLA08169 + Cw10 + Cw3 + + + C*03:40:04 + HLA12860 + Cw10 + Cw3 + + + C*03:41:01 + HLA02927 + Cw10 + - + + + C*03:41:02 + HLA11976 + Cw10 + - + + + C*03:42:01 + HLA02993 + Undefined + - + + + C*03:42:02 + HLA27690 + Undefined + - + + + C*03:43:01 + HLA02994 + Undefined + - + + + C*03:43:02 + HLA03544 + Undefined + - + + + C*03:44 + HLA02998 + Undefined + - + + + C*03:45 + HLA03027 + Undefined + - + + + C*03:46 + HLA02987 + Undefined + - + + + C*03:47 + HLA03163 + Undefined + - + + + C*03:48 + HLA03242 + Undefined + - + + + C*03:49 + HLA03362 + Undefined + - + + + C*03:50 + HLA03402 + Undefined + - + + + C*03:51 + HLA03723 + Undefined + - + + + C*03:52 + HLA03724 + Undefined + - + + + C*03:53 + HLA03725 + Undefined + - + + + C*03:54 + HLA03729 + Undefined + - + + + C*03:55 + HLA03733 + Undefined + - + + + C*03:56 + HLA03737 + Undefined + - + + + C*03:57:01 + HLA03687 + Undefined + - + + + C*03:57:02 + HLA14260 + Undefined + - + + + C*03:58 + HLA03713 + Undefined + - + + + C*03:59 + HLA03827 + Undefined + - + + + C*03:60 + HLA03828 + Undefined + - + + + C*03:61 + HLA03835 + Undefined + - + + + C*03:62 + HLA04134 + Undefined + - + + + C*03:63 + HLA04256 + Undefined + - + + + C*03:64:01 + HLA04257 + Undefined + - + + + C*03:64:02 + HLA08206 + Undefined + - + + + C*03:65 + HLA04259 + Undefined + - + + + C*03:66 + HLA04262 + Undefined + - + + + C*03:67 + HLA04266 + Undefined + - + + + C*03:68 + HLA04268 + Undefined + - + + + C*03:69 + HLA04269 + Undefined + - + + + C*03:70 + HLA04271 + Undefined + - + + + C*03:71 + HLA04273 + Undefined + - + + + C*03:72 + HLA04274 + Undefined + - + + + C*03:73 + HLA04279 + Undefined + - + + + C*03:74 + HLA04280 + Undefined + - + + + C*03:75 + HLA04282 + Undefined + - + + + C*03:76 + HLA04283 + Undefined + - + + + C*03:77 + HLA04595 + Undefined + - + + + C*03:78 + HLA04618 + Undefined + - + + + C*03:79 + HLA04633 + Undefined + - + + + C*03:80:01 + HLA04702 + Undefined + - + + + C*03:80:02 + HLA15897 + Undefined + - + + + C*03:81 + HLA04758 + Undefined + - + + + C*03:82 + HLA04777 + Undefined + - + + + C*03:83 + HLA04794 + Undefined + - + + + C*03:84 + HLA04822 + Undefined + - + + + C*03:85 + HLA05111 + Undefined + - + + + C*03:86 + HLA05122 + Undefined + - + + + C*03:87:01 + HLA05124 + Undefined + - + + + C*03:87:02 + HLA12784 + Undefined + - + + + C*03:88 + HLA05162 + Undefined + - + + + C*03:89 + HLA05169 + Undefined + - + + + C*03:90 + HLA05171 + Undefined + - + + + C*03:91:01 + HLA05197 + Undefined + - + + + C*03:91:02 + HLA11116 + Undefined + - + + + C*03:92 + HLA05202 + Undefined + - + + + C*03:93 + HLA05371 + Undefined + - + + + C*03:94:01 + HLA05396 + Undefined + - + + + C*03:94:02 + HLA38563 + Undefined + - + + + C*03:95 + HLA05605 + Undefined + - + + + C*03:96:01 + HLA05613 + Undefined + - + + + C*03:96:02 + HLA37114 + Undefined + - + + + C*03:97 + HLA05746 + Undefined + - + + + C*03:98 + HLA05747 + Undefined + - + + + C*03:100 + HLA05788 + Undefined + - + + + C*03:101 + HLA05870 + Undefined + - + + + C*03:102 + HLA05882 + Undefined + - + + + C*03:103 + HLA06067 + Undefined + - + + + C*03:104 + HLA06074 + Undefined + - + + + C*03:105 + HLA06150 + Undefined + - + + + C*03:106 + HLA06167 + Undefined + - + + + C*03:107 + HLA06169 + Undefined + - + + + C*03:108 + HLA06310 + Undefined + - + + + C*03:109 + HLA06398 + Undefined + - + + + C*03:110 + HLA06399 + Undefined + - + + + C*03:111 + HLA06417 + Undefined + - + + + C*03:112 + HLA06419 + Undefined + - + + + C*03:113:01 + HLA06711 + Undefined + - + + + C*03:113:02 + HLA15113 + Undefined + - + + + C*03:114 + HLA06712 + Undefined + - + + + C*03:115:01 + HLA06713 + Undefined + - + + + C*03:115:02 + HLA21462 + Undefined + - + + + C*03:116:01 + HLA06726 + Undefined + - + + + C*03:116:02 + HLA07950 + Undefined + - + + + C*03:117 + HLA06727 + Undefined + - + + + C*03:118 + HLA06894 + Undefined + - + + + C*03:119:01 + HLA07006 + Undefined + - + + + C*03:119:02 + HLA15893 + Undefined + - + + + C*03:120 + HLA07007 + Undefined + - + + + C*03:121N + HLA07008 + NotExpressed + Null + + + C*03:122 + HLA07013 + Undefined + - + + + C*03:123 + HLA07014 + Undefined + - + + + C*03:124 + HLA07016 + Undefined + - + + + C*03:125:01 + HLA07021 + Undefined + - + + + C*03:125:02 + HLA38694 + Undefined + - + + + C*03:126 + HLA07027 + Undefined + - + + + C*03:127 + HLA07029 + Undefined + - + + + C*03:128 + HLA07036 + Undefined + - + + + C*03:129 + HLA07118 + Undefined + - + + + C*03:130 + HLA07119 + Undefined + - + + + C*03:131 + HLA07124 + Undefined + - + + + C*03:132:01 + HLA07140 + Undefined + - + + + C*03:132:02 + HLA38700 + Undefined + - + + + C*03:133 + HLA07235 + Undefined + - + + + C*03:134 + HLA07238 + Undefined + - + + + C*03:135 + HLA07239 + Undefined + - + + + C*03:136 + HLA07240 + Undefined + - + + + C*03:137 + HLA07241 + Undefined + - + + + C*03:138 + HLA07315 + Undefined + - + + + C*03:139 + HLA07355 + Undefined + - + + + C*03:140:01:01 + HLA07495 + Undefined + - + + + C*03:140:01:02 + HLA26713 + Undefined + - + + + C*03:141 + HLA07496 + Undefined + - + + + C*03:142 + HLA07497 + Undefined + - + + + C*03:143 + HLA07498 + Undefined + - + + + C*03:144 + HLA07526 + Undefined + - + + + C*03:145 + HLA07537 + Undefined + - + + + C*03:146 + HLA07814 + Undefined + - + + + C*03:147 + HLA07940 + Undefined + - + + + C*03:148 + HLA07945 + Undefined + - + + + C*03:149 + HLA07946 + Undefined + - + + + C*03:150 + HLA07947 + Undefined + - + + + C*03:151 + HLA07948 + Undefined + - + + + C*03:152 + HLA07949 + Undefined + - + + + C*03:153 + HLA07951 + Undefined + - + + + C*03:154 + HLA07953 + Undefined + - + + + C*03:155 + HLA07955 + Undefined + - + + + C*03:156 + HLA07957 + Undefined + - + + + C*03:157 + HLA08168 + Undefined + - + + + C*03:158 + HLA08175 + Undefined + - + + + C*03:159 + HLA08176 + Undefined + - + + + C*03:160 + HLA08214 + Undefined + - + + + C*03:161 + HLA08215 + Undefined + - + + + C*03:162 + HLA08216 + Undefined + - + + + C*03:163 + HLA08217 + Undefined + - + + + C*03:164 + HLA08419 + Undefined + - + + + C*03:165:01 + HLA08477 + Undefined + - + + + C*03:165:02 + HLA18155 + Undefined + - + + + C*03:166 + HLA08530 + Undefined + - + + + C*03:167 + HLA08537 + Undefined + - + + + C*03:168 + HLA08538 + Undefined + - + + + C*03:169Q + HLA08540 + Undefined + - + + + C*03:170 + HLA08545 + Undefined + - + + + C*03:171 + HLA08582 + Undefined + - + + + C*03:172 + HLA08764 + Undefined + - + + + C*03:173 + HLA08766 + Undefined + - + + + C*03:174 + HLA08767 + Undefined + - + + + C*03:175 + HLA08768 + Undefined + - + + + C*03:176 + HLA08812 + Undefined + - + + + C*03:177 + HLA08813 + Undefined + - + + + C*03:178 + HLA08814 + Undefined + - + + + C*03:179 + HLA08815 + Undefined + - + + + C*03:180 + HLA08816 + Undefined + - + + + C*03:181 + HLA08817 + Undefined + - + + + C*03:182 + HLA08818 + Undefined + - + + + C*03:183 + HLA08954 + Undefined + - + + + C*03:184:01 + HLA09038 + Undefined + - + + + C*03:184:02 + HLA13573 + Undefined + - + + + C*03:185 + HLA09041 + Undefined + - + + + C*03:186:01 + HLA09197 + Undefined + - + + + C*03:186:02 + HLA11263 + Undefined + - + + + C*03:187 + HLA09198 + Undefined + - + + + C*03:188 + HLA09200 + Undefined + - + + + C*03:189N + HLA09201 + NotExpressed + Null + + + C*03:190 + HLA09330 + Undefined + - + + + C*03:191 + HLA09597 + Undefined + - + + + C*03:192 + HLA09624 + Undefined + - + + + C*03:193 + HLA09625 + Undefined + - + + + C*03:194 + HLA09626 + Undefined + - + + + C*03:195 + HLA09671 + Undefined + - + + + C*03:196 + HLA09931 + Undefined + - + + + C*03:197 + HLA09943 + Undefined + - + + + C*03:198 + HLA09945 + Undefined + - + + + C*03:199 + HLA09947 + Undefined + - + + + C*03:200 + HLA09948 + Undefined + - + + + C*03:201N + HLA09950 + NotExpressed + Null + + + C*03:202 + HLA09952 + Undefined + - + + + C*03:203 + HLA09954 + Undefined + - + + + C*03:204 + HLA09962 + Undefined + - + + + C*03:205 + HLA09964 + Undefined + - + + + C*03:206 + HLA09966 + Undefined + - + + + C*03:207 + HLA09968 + Undefined + - + + + C*03:208N + HLA09970 + NotExpressed + Null + + + C*03:209 + HLA09976 + Undefined + - + + + C*03:210 + HLA09979 + Undefined + - + + + C*03:211:01 + HLA09985 + Undefined + - + + + C*03:211:02 + HLA10593 + Undefined + - + + + C*03:212 + HLA09987 + Undefined + - + + + C*03:213 + HLA09989 + Undefined + - + + + C*03:214 + HLA10101 + Undefined + - + + + C*03:215 + HLA10102 + Undefined + - + + + C*03:216 + HLA10104 + Undefined + - + + + C*03:217 + HLA10106 + Undefined + - + + + C*03:218 + HLA10168 + Undefined + - + + + C*03:219 + HLA10252 + Undefined + - + + + C*03:220 + HLA10258 + Undefined + - + + + C*03:221 + HLA10441 + Undefined + - + + + C*03:222 + HLA10442 + Undefined + - + + + C*03:223 + HLA10509 + Undefined + - + + + C*03:224N + HLA10574 + NotExpressed + Null + + + C*03:225 + HLA10576 + Undefined + - + + + C*03:226 + HLA10577 + Undefined + - + + + C*03:227 + HLA10578 + Undefined + - + + + C*03:228 + HLA10581 + Undefined + - + + + C*03:229N + HLA10583 + NotExpressed + Null + + + C*03:230 + HLA10586 + Undefined + - + + + C*03:231 + HLA10588 + Undefined + - + + + C*03:232 + HLA10589 + Undefined + - + + + C*03:233 + HLA10590 + Undefined + - + + + C*03:234 + HLA10591 + Undefined + - + + + C*03:235 + HLA10592 + Undefined + - + + + C*03:236 + HLA10596 + Undefined + - + + + C*03:237 + HLA10904 + Undefined + - + + + C*03:238 + HLA10916 + Undefined + - + + + C*03:239 + HLA10929 + Undefined + - + + + C*03:240 + HLA11063 + Undefined + - + + + C*03:241 + HLA11342 + Undefined + - + + + C*03:242 + HLA11114 + Undefined + - + + + C*03:243 + HLA11264 + Undefined + - + + + C*03:244Q + HLA11265 + Undefined + - + + + C*03:245 + HLA11266 + Undefined + - + + + C*03:246 + HLA11341 + Undefined + - + + + C*03:247 + HLA11572 + Undefined + - + + + C*03:248 + HLA11578 + Undefined + - + + + C*03:249 + HLA11579 + Undefined + - + + + C*03:250 + HLA11668 + Undefined + - + + + C*03:251 + HLA11711 + Undefined + - + + + C*03:252 + HLA11762 + Undefined + - + + + C*03:253 + HLA11870 + Undefined + - + + + C*03:254 + HLA11871 + Undefined + - + + + C*03:255 + HLA11872 + Undefined + - + + + C*03:256 + HLA11873 + Undefined + - + + + C*03:257 + HLA11875 + Undefined + - + + + C*03:258 + HLA12023 + Undefined + - + + + C*03:259 + HLA11975 + Undefined + - + + + C*03:260 + HLA12172 + Undefined + - + + + C*03:261 + HLA12153 + Undefined + - + + + C*03:262 + HLA12157 + Undefined + - + + + C*03:263:01 + HLA12199 + Undefined + - + + + C*03:263:02 + HLA15923 + Undefined + - + + + C*03:263:03 + HLA20585 + Undefined + - + + + C*03:264 + HLA12331 + Undefined + - + + + C*03:265N + HLA12343 + NotExpressed + Null + + + C*03:266 + HLA12344 + Undefined + - + + + C*03:267 + HLA12430 + Undefined + - + + + C*03:268 + HLA12509 + Undefined + - + + + C*03:269 + HLA12511 + Undefined + - + + + C*03:270 + HLA12512 + Undefined + - + + + C*03:271 + HLA12730 + Undefined + - + + + C*03:272 + HLA12782 + Undefined + - + + + C*03:273 + HLA12783 + Undefined + - + + + C*03:274 + HLA12786 + Undefined + - + + + C*03:275 + HLA12787 + Undefined + - + + + C*03:276 + HLA12875 + Undefined + - + + + C*03:277N + HLA12858 + NotExpressed + Null + + + C*03:278 + HLA13028 + Undefined + - + + + C*03:279 + HLA13188 + Undefined + - + + + C*03:280 + HLA13198 + Undefined + - + + + C*03:281 + HLA13239 + Undefined + - + + + C*03:282 + HLA13260 + Undefined + - + + + C*03:283 + HLA13261 + Undefined + - + + + C*03:284 + HLA13262 + Undefined + - + + + C*03:285 + HLA13411 + Undefined + - + + + C*03:286 + HLA13420 + Undefined + - + + + C*03:287:01 + HLA13427 + Undefined + - + + + C*03:287:02 + HLA19502 + Undefined + - + + + C*03:288 + HLA13514 + Undefined + - + + + C*03:289 + HLA13523 + Undefined + - + + + C*03:290 + HLA13533 + Undefined + - + + + C*03:291 + HLA13571 + Undefined + - + + + C*03:292 + HLA13572 + Undefined + - + + + C*03:293 + HLA13574 + Undefined + - + + + C*03:294 + HLA13505 + Undefined + - + + + C*03:295 + HLA13510 + Undefined + - + + + C*03:296:01 + HLA13670 + Undefined + - + + + C*03:296:02 + HLA18381 + Undefined + - + + + C*03:297 + HLA13671 + Undefined + - + + + C*03:298 + HLA13802 + Undefined + - + + + C*03:299 + HLA13803 + Undefined + - + + + C*03:300 + HLA13876 + Undefined + - + + + C*03:301 + HLA14030 + Undefined + - + + + C*03:302 + HLA14095 + Undefined + - + + + C*03:303 + HLA14112 + Undefined + - + + + C*03:304 + HLA14259 + Undefined + - + + + C*03:305 + HLA14261 + Undefined + - + + + C*03:306 + HLA14262 + Undefined + - + + + C*03:307 + HLA14338 + Undefined + - + + + C*03:308 + HLA14537 + Undefined + - + + + C*03:309 + HLA14540 + Undefined + - + + + C*03:310 + HLA14541 + Undefined + - + + + C*03:311 + HLA14488 + Undefined + - + + + C*03:312 + HLA14461 + Undefined + - + + + C*03:313 + HLA14467 + Undefined + - + + + C*03:314 + HLA14754 + Undefined + - + + + C*03:315 + HLA14755 + Undefined + - + + + C*03:316N + HLA14756 + NotExpressed + Null + + + C*03:317 + HLA14860 + Undefined + - + + + C*03:318N + HLA15129 + NotExpressed + Null + + + C*03:319 + HLA15060 + Undefined + - + + + C*03:320 + HLA15138 + Undefined + - + + + C*03:321 + HLA14956 + Undefined + - + + + C*03:322 + HLA15310 + Undefined + - + + + C*03:323N + HLA15311 + NotExpressed + Null + + + C*03:324 + HLA15214 + Undefined + - + + + C*03:325 + HLA15473 + Undefined + - + + + C*03:326 + HLA15474 + Undefined + - + + + C*03:327 + HLA15416 + Undefined + - + + + C*03:328 + HLA15665 + Undefined + - + + + C*03:329 + HLA15666 + Undefined + - + + + C*03:330 + HLA15667 + Undefined + - + + + C*03:331 + HLA15668 + Undefined + - + + + C*03:332 + HLA15669 + Undefined + - + + + C*03:333 + HLA15670 + Undefined + - + + + C*03:334 + HLA15671 + Undefined + - + + + C*03:335 + HLA15571 + Undefined + - + + + C*03:336 + HLA15621 + Undefined + - + + + C*03:337 + HLA15794 + Undefined + - + + + C*03:338 + HLA15800 + Undefined + - + + + C*03:339 + HLA15917 + Undefined + - + + + C*03:340 + HLA15936 + Undefined + - + + + C*03:341 + HLA15758 + Undefined + - + + + C*03:342 + HLA15984 + Undefined + - + + + C*03:343 + HLA15985 + Undefined + - + + + C*03:344:01:01 + HLA16060 + Undefined + - + + + C*03:344:01:02 + HLA19323 + Undefined + - + + + C*03:345 + HLA16542 + Undefined + - + + + C*03:346 + HLA16543 + Undefined + - + + + C*03:347 + HLA16544 + Undefined + - + + + C*03:348 + HLA16545 + Undefined + - + + + C*03:349 + HLA16547 + Undefined + - + + + C*03:350 + HLA16548 + Undefined + - + + + C*03:351 + HLA16623 + Undefined + - + + + C*03:352 + HLA16769 + Undefined + - + + + C*03:353 + HLA16770 + Undefined + - + + + C*03:354 + HLA16845 + Undefined + - + + + C*03:355 + HLA16947 + Undefined + - + + + C*03:356 + HLA16949 + Undefined + - + + + C*03:357 + HLA17274 + Undefined + - + + + C*03:358 + HLA17277 + Undefined + - + + + C*03:359 + HLA17287 + Undefined + - + + + C*03:360 + HLA17322 + Undefined + - + + + C*03:361 + HLA17326 + Undefined + - + + + C*03:362 + HLA17417 + Undefined + - + + + C*03:363N + HLA17514 + NotExpressed + Null + + + C*03:364 + HLA17515 + Undefined + - + + + C*03:365 + HLA17468 + Undefined + - + + + C*03:366N + HLA17629 + NotExpressed + Null + + + C*03:367 + HLA17645 + Undefined + - + + + C*03:368 + HLA17897 + Undefined + - + + + C*03:369 + HLA17974 + Undefined + - + + + C*03:370 + HLA18043 + Undefined + - + + + C*03:371 + HLA18054 + Undefined + - + + + C*03:372:01 + HLA18113 + Undefined + - + + + C*03:372:02 + HLA24019 + Undefined + - + + + C*03:373 + HLA18114 + Undefined + - + + + C*03:374 + HLA18145 + Undefined + - + + + C*03:375 + HLA18152 + Undefined + - + + + C*03:376 + HLA18274 + Undefined + - + + + C*03:377N + HLA18185 + NotExpressed + Null + + + C*03:378 + HLA18404 + Undefined + - + + + C*03:379 + HLA18456 + Undefined + - + + + C*03:380N + HLA18460 + NotExpressed + Null + + + C*03:381 + HLA18463 + Undefined + - + + + C*03:382 + HLA18474 + Undefined + - + + + C*03:383 + HLA18544 + Undefined + - + + + C*03:384 + HLA18570 + Undefined + - + + + C*03:385 + HLA18576 + Undefined + - + + + C*03:386 + HLA18578 + Undefined + - + + + C*03:387 + HLA18579 + Undefined + - + + + C*03:388 + HLA18519 + Undefined + - + + + C*03:389 + HLA18856 + Undefined + - + + + C*03:390 + HLA19085 + Undefined + - + + + C*03:391N + HLA19581 + NotExpressed + Null + + + C*03:392N + HLA19462 + NotExpressed + Null + + + C*03:393 + HLA19381 + Undefined + - + + + C*03:394 + HLA19452 + Undefined + - + + + C*03:395 + HLA19319 + Undefined + - + + + C*03:396:01N + HLA19332 + NotExpressed + Null + + + C*03:396:02N + HLA30545 + NotExpressed + Null + + + C*03:397 + HLA19508 + Undefined + - + + + C*03:398 + HLA19493 + Undefined + - + + + C*03:399 + HLA19548 + Undefined + - + + + C*03:400 + HLA19441 + Undefined + - + + + C*03:401 + HLA19271 + Undefined + - + + + C*03:402 + HLA19898 + Undefined + - + + + C*03:403 + HLA19795 + Undefined + - + + + C*03:404:01:01 + HLA19722 + Undefined + - + + + C*03:404:01:02 + HLA27700 + Undefined + - + + + C*03:405 + HLA19909 + Undefined + - + + + C*03:406 + HLA19646 + Undefined + - + + + C*03:407 + HLA19907 + Undefined + - + + + C*03:408 + HLA19720 + Undefined + - + + + C*03:409 + HLA19922 + Undefined + - + + + C*03:410 + HLA19780 + Undefined + - + + + C*03:411 + HLA19729 + Undefined + - + + + C*03:412 + HLA20427 + Undefined + - + + + C*03:413 + HLA20281 + Undefined + - + + + C*03:414 + HLA20273 + Undefined + - + + + C*03:415 + HLA20209 + Undefined + - + + + C*03:416 + HLA20123 + Undefined + - + + + C*03:417 + HLA20004 + Undefined + - + + + C*03:418 + HLA20446 + Undefined + - + + + C*03:419 + HLA20481 + Undefined + - + + + C*03:420 + HLA19966 + Undefined + - + + + C*03:421N + HLA20255 + NotExpressed + Null + + + C*03:422 + HLA19957 + Undefined + - + + + C*03:423 + HLA20258 + Undefined + - + + + C*03:424N + HLA20320 + NotExpressed + Null + + + C*03:425 + HLA20261 + Undefined + - + + + C*03:426 + HLA20205 + Undefined + - + + + C*03:427 + HLA20364 + Undefined + - + + + C*03:428 + HLA21049 + Undefined + - + + + C*03:429 + HLA20853 + Undefined + - + + + C*03:430 + HLA21069 + Undefined + - + + + C*03:431 + HLA20537 + Undefined + - + + + C*03:432N + HLA20790 + NotExpressed + Null + + + C*03:433 + HLA20678 + Undefined + - + + + C*03:434 + HLA20789 + Undefined + - + + + C*03:435 + HLA20716 + Undefined + - + + + C*03:436 + HLA21144 + Undefined + - + + + C*03:437 + HLA21065 + Undefined + - + + + C*03:438 + HLA20522 + Undefined + - + + + C*03:439 + HLA20829 + Undefined + - + + + C*03:440 + HLA21029 + Undefined + - + + + C*03:441 + HLA20943 + Undefined + - + + + C*03:442Q + HLA21245 + Undefined + - + + + C*03:443 + HLA21379 + Undefined + - + + + C*03:444N + HLA21681 + NotExpressed + Null + + + C*03:445N + HLA21886 + NotExpressed + Null + + + C*03:446N + HLA21895 + NotExpressed + Null + + + C*03:447N + HLA21791 + NotExpressed + Null + + + C*03:448Q + HLA21632 + Undefined + - + + + C*03:449N + HLA21909 + NotExpressed + Null + + + C*03:450 + HLA21859 + Undefined + - + + + C*03:451 + HLA21781 + Undefined + - + + + C*03:452 + HLA21697 + Undefined + - + + + C*03:453 + HLA21620 + Undefined + - + + + C*03:454 + HLA21802 + Undefined + - + + + C*03:455 + HLA21876 + Undefined + - + + + C*03:456 + HLA21893 + Undefined + - + + + C*03:457 + HLA21669 + Undefined + - + + + C*03:458 + HLA21811 + Undefined + - + + + C*03:459 + HLA21634 + Undefined + - + + + C*03:460 + HLA21775 + Undefined + - + + + C*03:461 + HLA22094 + Undefined + - + + + C*03:462N + HLA22294 + NotExpressed + Null + + + C*03:463N + HLA22575 + NotExpressed + Null + + + C*03:464 + HLA22686 + Undefined + - + + + C*03:465 + HLA22800 + Undefined + - + + + C*03:466 + HLA22783 + Undefined + - + + + C*03:467 + HLA23003 + Undefined + - + + + C*03:468 + HLA23483 + Undefined + - + + + C*03:469 + HLA23401 + Undefined + - + + + C*03:470N + HLA23703 + NotExpressed + Null + + + C*03:471 + HLA23697 + Undefined + - + + + C*03:472 + HLA23139 + Undefined + - + + + C*03:473 + HLA23229 + Undefined + - + + + C*03:474 + HLA23632 + Undefined + - + + + C*03:475 + HLA23469 + Undefined + - + + + C*03:476 + HLA23296 + Undefined + - + + + C*03:477 + HLA23500 + Undefined + - + + + C*03:478 + HLA23777 + Undefined + - + + + C*03:479 + HLA23589 + Undefined + - + + + C*03:480:01 + HLA24296 + Undefined + - + + + C*03:480:02 + HLA37358 + Undefined + - + + + C*03:481 + HLA23893 + Undefined + - + + + C*03:482 + HLA24040 + Undefined + - + + + C*03:483 + HLA24273 + Undefined + - + + + C*03:484 + HLA24004 + Undefined + - + + + C*03:485 + HLA24003 + Undefined + - + + + C*03:486 + HLA24079 + Undefined + - + + + C*03:487 + HLA23972 + Undefined + - + + + C*03:488 + HLA23871 + Undefined + - + + + C*03:489 + HLA23968 + Undefined + - + + + C*03:490 + HLA25496 + Undefined + - + + + C*03:491:01 + HLA24367 + Undefined + - + + + C*03:491:02 + HLA27121 + Undefined + - + + + C*03:492 + HLA25089 + Undefined + - + + + C*03:493 + HLA24393 + Undefined + - + + + C*03:494 + HLA24593 + Undefined + - + + + C*03:495 + HLA25536 + Undefined + - + + + C*03:496 + HLA25371 + Undefined + - + + + C*03:497 + HLA24608 + Undefined + - + + + C*03:498 + HLA26074 + Undefined + - + + + C*03:499 + HLA25942 + Undefined + - + + + C*03:500 + HLA26013 + Undefined + - + + + C*03:501 + HLA25739 + Undefined + - + + + C*03:502Q + HLA25809 + Undefined + - + + + C*03:503 + HLA25810 + Undefined + - + + + C*03:504 + HLA26184 + Undefined + - + + + C*03:505 + HLA26350 + Undefined + - + + + C*03:506 + HLA26641 + Undefined + - + + + C*03:507 + HLA26778 + Undefined + - + + + C*03:508N + HLA27150 + NotExpressed + Null + + + C*03:509N + HLA27157 + NotExpressed + Null + + + C*03:510N + HLA27167 + NotExpressed + Null + + + C*03:511N + HLA27171 + NotExpressed + Null + + + C*03:512 + HLA27181 + Undefined + - + + + C*03:513 + HLA27184 + Undefined + - + + + C*03:514 + HLA27185 + Undefined + - + + + C*03:515 + HLA27186 + Undefined + - + + + C*03:516 + HLA27487 + Undefined + - + + + C*03:517 + HLA27332 + Undefined + - + + + C*03:518 + HLA27691 + Undefined + - + + + C*03:519 + HLA27692 + Undefined + - + + + C*03:520 + HLA27701 + Undefined + - + + + C*03:521 + HLA27615 + Undefined + - + + + C*03:522 + HLA27826 + Undefined + - + + + C*03:523 + HLA27834 + Undefined + - + + + C*03:524 + HLA27844 + Undefined + - + + + C*03:525 + HLA28149 + Undefined + - + + + C*03:526 + HLA28159 + Undefined + - + + + C*03:527 + HLA28178 + Undefined + - + + + C*03:528 + HLA28107 + Undefined + - + + + C*03:529 + HLA28111 + Undefined + - + + + C*03:530 + HLA28349 + Undefined + - + + + C*03:531N + HLA28266 + NotExpressed + Null + + + C*03:532 + HLA28268 + Undefined + - + + + C*03:533 + HLA28269 + Undefined + - + + + C*03:534 + HLA28285 + Undefined + - + + + C*03:535:01:01 + HLA28287 + Undefined + - + + + C*03:535:01:02 + HLA33536 + Undefined + - + + + C*03:536 + HLA28298 + Undefined + - + + + C*03:537 + HLA28428 + Undefined + - + + + C*03:538 + HLA28429 + Undefined + - + + + C*03:539 + HLA29031 + Undefined + - + + + C*03:540 + HLA28823 + Undefined + - + + + C*03:541 + HLA28915 + Undefined + - + + + C*03:542 + HLA28916 + Undefined + - + + + C*03:543 + HLA29221 + Undefined + - + + + C*03:544 + HLA29391 + Undefined + - + + + C*03:545 + HLA29409 + Undefined + - + + + C*03:546 + HLA30466 + Undefined + - + + + C*03:547 + HLA30161 + Undefined + - + + + C*03:548 + HLA30392 + Undefined + - + + + C*03:549 + HLA30196 + Undefined + - + + + C*03:550 + HLA29983 + Undefined + - + + + C*03:551 + HLA29988 + Undefined + - + + + C*03:552 + HLA29995 + Undefined + - + + + C*03:553 + HLA30033 + Undefined + - + + + C*03:554 + HLA29999 + Undefined + - + + + C*03:555 + HLA29965 + Undefined + - + + + C*03:556 + HLA30004 + Undefined + - + + + C*03:557 + HLA30591 + Undefined + - + + + C*03:558 + HLA30681 + Undefined + - + + + C*03:559 + HLA30546 + Undefined + - + + + C*03:560N + HLA30505 + NotExpressed + Null + + + C*03:561 + HLA30786 + Undefined + - + + + C*03:562 + HLA30861 + Undefined + - + + + C*03:563 + HLA30867 + Undefined + - + + + C*03:564 + HLA31085 + Undefined + - + + + C*03:565 + HLA31174 + Undefined + - + + + C*03:566 + HLA31303 + Undefined + - + + + C*03:567 + HLA31268 + Undefined + - + + + C*03:568 + HLA31262 + Undefined + - + + + C*03:569 + HLA31162 + Undefined + - + + + C*03:570 + HLA31728 + Undefined + - + + + C*03:571N + HLA31713 + NotExpressed + Null + + + C*03:572 + HLA31695 + Undefined + - + + + C*03:573 + HLA32003 + Undefined + - + + + C*03:574 + HLA32118 + Undefined + - + + + C*03:575Q + HLA32050 + Undefined + - + + + C*03:576 + HLA32466 + Undefined + - + + + C*03:577 + HLA33253 + Undefined + - + + + C*03:578 + HLA32758 + Undefined + - + + + C*03:579 + HLA32970 + Undefined + - + + + C*03:580 + HLA33360 + Undefined + - + + + C*03:581 + HLA33234 + Undefined + - + + + C*03:582 + HLA33136 + Undefined + - + + + C*03:583 + HLA33534 + Undefined + - + + + C*03:584 + HLA33650 + Undefined + - + + + C*03:585 + HLA33526 + Undefined + - + + + C*03:586Q + HLA33631 + Undefined + - + + + C*03:587 + HLA33654 + Undefined + - + + + C*03:588 + HLA33669 + Undefined + - + + + C*03:589 + HLA33510 + Undefined + - + + + C*03:590 + HLA33984 + Undefined + - + + + C*03:591 + HLA33941 + Undefined + - + + + C*03:592 + HLA34236 + Undefined + - + + + C*03:593 + HLA34330 + Undefined + - + + + C*03:594 + HLA34405 + Undefined + - + + + C*03:595 + HLA34279 + Undefined + - + + + C*03:596 + HLA34274 + Undefined + - + + + C*03:597 + HLA34574 + Undefined + - + + + C*03:598 + HLA34563 + Undefined + - + + + C*03:599 + HLA35220 + Undefined + - + + + C*03:600 + HLA35061 + Undefined + - + + + C*03:601 + HLA35305 + Undefined + - + + + C*03:602 + HLA35125 + Undefined + - + + + C*03:603 + HLA34840 + Undefined + - + + + C*03:604 + HLA35267 + Undefined + - + + + C*03:605 + HLA35135 + Undefined + - + + + C*03:606 + HLA35093 + Undefined + - + + + C*03:607 + HLA35526 + Undefined + - + + + C*03:608 + HLA35414 + Undefined + - + + + C*03:609 + HLA35417 + Undefined + - + + + C*03:610 + HLA35563 + Undefined + - + + + C*03:611 + HLA35615 + Undefined + - + + + C*03:612 + HLA35438 + Undefined + - + + + C*03:613 + HLA35491 + Undefined + - + + + C*03:614 + HLA35421 + Undefined + - + + + C*03:615 + HLA35777 + Undefined + - + + + C*03:616 + HLA35863 + Undefined + - + + + C*03:617 + HLA35939 + Undefined + - + + + C*03:618N + HLA36108 + NotExpressed + Null + + + C*03:619N + HLA36079 + NotExpressed + Null + + + C*03:620 + HLA36004 + Undefined + - + + + C*03:621 + HLA36430 + Undefined + - + + + C*03:622 + HLA36676 + Undefined + - + + + C*03:623 + HLA36629 + Undefined + - + + + C*03:624 + HLA36610 + Undefined + - + + + C*03:625N + HLA36892 + NotExpressed + Null + + + C*03:626 + HLA36896 + Undefined + - + + + C*03:627 + HLA36819 + Undefined + - + + + C*03:628N + HLA36987 + NotExpressed + Null + + + C*03:629 + HLA37006 + Undefined + - + + + C*03:630 + HLA36981 + Undefined + - + + + C*03:631 + HLA37019 + Undefined + - + + + C*03:632 + HLA36941 + Undefined + - + + + C*03:633 + HLA37351 + Undefined + - + + + C*03:634 + HLA37330 + Undefined + - + + + C*03:635N + HLA37343 + NotExpressed + Null + + + C*03:636N + HLA37357 + NotExpressed + Null + + + C*03:637:01 + HLA37397 + Undefined + - + + + C*03:637:02 + HLA37575 + Undefined + - + + + C*03:638 + HLA37506 + Undefined + - + + + C*03:639 + HLA37690 + Undefined + - + + + C*03:640 + HLA37907 + Undefined + - + + + C*03:641 + HLA38085 + Undefined + - + + + C*03:642 + HLA38083 + Undefined + - + + + C*03:643N + HLA38380 + NotExpressed + Null + + + C*03:644 + HLA38452 + Undefined + - + + + C*03:645 + HLA38628 + Undefined + - + + + C*03:646 + HLA38692 + Undefined + - + + + C*03:647 + HLA38660 + Undefined + - + + + C*04:01:01:01 + HLA00420 + Cw4 + Cw4 + + + C*04:01:01:02 + HLA01328 + Cw4 + Cw4 + + + C*04:01:01:03 + HLA03572 + Cw4 + Cw4 + + + C*04:01:01:04 + HLA05787 + Cw4 + Cw4 + + + C*04:01:01:05 + HLA08080 + Cw4 + Cw4 + + + C*04:01:01:06 + HLA13527 + Cw4 + Cw4 + + + C*04:01:01:07 + HLA15141 + Cw4 + Cw4 + + + C*04:01:01:08 + HLA16711 + Cw4 + Cw4 + + + C*04:01:01:09 + HLA16712 + Cw4 + Cw4 + + + C*04:01:01:10 + HLA16713 + Cw4 + Cw4 + + + C*04:01:01:11 + HLA16822 + Cw4 + Cw4 + + + C*04:01:01:12 + HLA17055 + Cw4 + Cw4 + + + C*04:01:01:13 + HLA17679 + Cw4 + Cw4 + + + C*04:01:01:14 + HLA17684 + Cw4 + Cw4 + + + C*04:01:01:15 + HLA18013 + Cw4 + Cw4 + + + C*04:01:01:16 + HLA17984 + Cw4 + Cw4 + + + C*04:01:01:17 + HLA18128 + Cw4 + Cw4 + + + C*04:01:01:18 + HLA18129 + Cw4 + Cw4 + + + C*04:01:01:19 + HLA18227 + Cw4 + Cw4 + + + C*04:01:01:20 + HLA18256 + Cw4 + Cw4 + + + C*04:01:01:21 + HLA18257 + Cw4 + Cw4 + + + C*04:01:01:22 + HLA18258 + Cw4 + Cw4 + + + C*04:01:01:23 + HLA19888 + Cw4 + Cw4 + + + C*04:01:01:24 + HLA19671 + Cw4 + Cw4 + + + C*04:01:01:25 + HLA20147 + Cw4 + Cw4 + + + C*04:01:01:26 + HLA20297 + Cw4 + Cw4 + + + C*04:01:01:27 + HLA20859 + Cw4 + Cw4 + + + C*04:01:01:28 + HLA21078 + Cw4 + Cw4 + + + C*04:01:01:29 + HLA20640 + Cw4 + Cw4 + + + C*04:01:01:31 + HLA21152 + Cw4 + Cw4 + + + C*04:01:01:32 + HLA21448 + Cw4 + Cw4 + + + C*04:01:01:33 + HLA21655 + Cw4 + Cw4 + + + C*04:01:01:34 + HLA22848 + Cw4 + Cw4 + + + C*04:01:01:35 + HLA23719 + Cw4 + Cw4 + + + C*04:01:01:36 + HLA25305 + Cw4 + Cw4 + + + C*04:01:01:37 + HLA25414 + Cw4 + Cw4 + + + C*04:01:01:38 + HLA24515 + Cw4 + Cw4 + + + C*04:01:01:39 + HLA24557 + Cw4 + Cw4 + + + C*04:01:01:40 + HLA24921 + Cw4 + Cw4 + + + C*04:01:01:41 + HLA25370 + Cw4 + Cw4 + + + C*04:01:01:42 + HLA24614 + Cw4 + Cw4 + + + C*04:01:01:43 + HLA24561 + Cw4 + Cw4 + + + C*04:01:01:44 + HLA24911 + Cw4 + Cw4 + + + C*04:01:01:45 + HLA25338 + Cw4 + Cw4 + + + C*04:01:01:46 + HLA25137 + Cw4 + Cw4 + + + C*04:01:01:47Q + HLA25257 + Undefined + - + + + C*04:01:01:48 + HLA24479 + Cw4 + Cw4 + + + C*04:01:01:49 + HLA25559 + Cw4 + Cw4 + + + C*04:01:01:50 + HLA25106 + Cw4 + Cw4 + + + C*04:01:01:51 + HLA24963 + Cw4 + Cw4 + + + C*04:01:01:52 + HLA24507 + Cw4 + Cw4 + + + C*04:01:01:53 + HLA24404 + Cw4 + Cw4 + + + C*04:01:01:54 + HLA24469 + Cw4 + Cw4 + + + C*04:01:01:55 + HLA25096 + Cw4 + Cw4 + + + C*04:01:01:56 + HLA25494 + Cw4 + Cw4 + + + C*04:01:01:57 + HLA25032 + Cw4 + Cw4 + + + C*04:01:01:58 + HLA25191 + Cw4 + Cw4 + + + C*04:01:01:59 + HLA25262 + Cw4 + Cw4 + + + C*04:01:01:60 + HLA24510 + Cw4 + Cw4 + + + C*04:01:01:61 + HLA25381 + Cw4 + Cw4 + + + C*04:01:01:62 + HLA25419 + Cw4 + Cw4 + + + C*04:01:01:63 + HLA24679 + Cw4 + Cw4 + + + C*04:01:01:64 + HLA25365 + Cw4 + Cw4 + + + C*04:01:01:65 + HLA24941 + Cw4 + Cw4 + + + C*04:01:01:66 + HLA24765 + Cw4 + Cw4 + + + C*04:01:01:67 + HLA25285 + Cw4 + Cw4 + + + C*04:01:01:68 + HLA25112 + Cw4 + Cw4 + + + C*04:01:01:69 + HLA24681 + Cw4 + Cw4 + + + C*04:01:01:70 + HLA25110 + Cw4 + Cw4 + + + C*04:01:01:71 + HLA24993 + Cw4 + Cw4 + + + C*04:01:01:72 + HLA25134 + Cw4 + Cw4 + + + C*04:01:01:73 + HLA24562 + Cw4 + Cw4 + + + C*04:01:01:74 + HLA25505 + Cw4 + Cw4 + + + C*04:01:01:75 + HLA25533 + Cw4 + Cw4 + + + C*04:01:01:76 + HLA25978 + Cw4 + Cw4 + + + C*04:01:01:77 + HLA25956 + Cw4 + Cw4 + + + C*04:01:01:78 + HLA26126 + Cw4 + Cw4 + + + C*04:01:01:79 + HLA26880 + Cw4 + Cw4 + + + C*04:01:01:80 + HLA26795 + Cw4 + Cw4 + + + C*04:01:01:81 + HLA26849 + Cw4 + Cw4 + + + C*04:01:01:82 + HLA27117 + Cw4 + Cw4 + + + C*04:01:01:83 + HLA27120 + Cw4 + Cw4 + + + C*04:01:01:84Q + HLA27122 + Undefined + - + + + C*04:01:01:85 + HLA27126 + Cw4 + Cw4 + + + C*04:01:01:86 + HLA27142 + Cw4 + Cw4 + + + C*04:01:01:87 + HLA27152 + Cw4 + Cw4 + + + C*04:01:01:88 + HLA27162 + Cw4 + Cw4 + + + C*04:01:01:89 + HLA27163 + Cw4 + Cw4 + + + C*04:01:01:90 + HLA27257 + Cw4 + Cw4 + + + C*04:01:01:91 + HLA27529 + Cw4 + Cw4 + + + C*04:01:01:92 + HLA27531 + Cw4 + Cw4 + + + C*04:01:01:93 + HLA27535 + Cw4 + Cw4 + + + C*04:01:01:94 + HLA27569 + Cw4 + Cw4 + + + C*04:01:01:95 + HLA27580 + Cw4 + Cw4 + + + C*04:01:01:96 + HLA27808 + Cw4 + Cw4 + + + C*04:01:01:97 + HLA27838 + Cw4 + Cw4 + + + C*04:01:01:98 + HLA27839 + Cw4 + Cw4 + + + C*04:01:01:99 + HLA27855 + Cw4 + Cw4 + + + C*04:01:01:100 + HLA28157 + Cw4 + Cw4 + + + C*04:01:01:101 + HLA28662 + Cw4 + Cw4 + + + C*04:01:01:102 + HLA28505 + Cw4 + Cw4 + + + C*04:01:01:103 + HLA28511 + Cw4 + Cw4 + + + C*04:01:01:104 + HLA29669 + Cw4 + Cw4 + + + C*04:01:01:105 + HLA29670 + Cw4 + Cw4 + + + C*04:01:01:106 + HLA29671 + Cw4 + Cw4 + + + C*04:01:01:107 + HLA29860 + Cw4 + Cw4 + + + C*04:01:01:108 + HLA29863 + Cw4 + Cw4 + + + C*04:01:01:109 + HLA29846 + Cw4 + Cw4 + + + C*04:01:01:110 + HLA29832 + Cw4 + Cw4 + + + C*04:01:01:111 + HLA29844 + Cw4 + Cw4 + + + C*04:01:01:112 + HLA29853 + Cw4 + Cw4 + + + C*04:01:01:113 + HLA29842 + Cw4 + Cw4 + + + C*04:01:01:114 + HLA29837 + Cw4 + Cw4 + + + C*04:01:01:115 + HLA29698 + Cw4 + Cw4 + + + C*04:01:01:116 + HLA30490 + Cw4 + Cw4 + + + C*04:01:01:117 + HLA30129 + Cw4 + Cw4 + + + C*04:01:01:118 + HLA30319 + Cw4 + Cw4 + + + C*04:01:01:119 + HLA30076 + Cw4 + Cw4 + + + C*04:01:01:120 + HLA30458 + Cw4 + Cw4 + + + C*04:01:01:121 + HLA30403 + Cw4 + Cw4 + + + C*04:01:01:122 + HLA29957 + Cw4 + Cw4 + + + C*04:01:01:123 + HLA29985 + Cw4 + Cw4 + + + C*04:01:01:124 + HLA30667 + Cw4 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HLA03128 + Undefined + - + + + C*04:32 + HLA03214 + Undefined + - + + + C*04:33 + HLA03364 + Undefined + - + + + C*04:34 + HLA03404 + Undefined + - + + + C*04:35:01 + HLA03430 + Undefined + - + + + C*04:35:02 + HLA23733 + Undefined + - + + + C*04:36 + HLA03437 + Undefined + - + + + C*04:37 + HLA03527 + Undefined + - + + + C*04:38 + HLA03678 + Undefined + - + + + C*04:39 + HLA03735 + Undefined + - + + + C*04:40 + HLA03699 + Undefined + - + + + C*04:41 + HLA03832 + Undefined + - + + + C*04:42:01 + HLA03992 + Undefined + - + + + C*04:42:02 + HLA11853 + Undefined + - + + + C*04:43 + HLA04276 + Undefined + - + + + C*04:44 + HLA04298 + Undefined + - + + + C*04:45 + HLA04300 + Undefined + - + + + C*04:46 + HLA04301 + Undefined + - + + + C*04:47 + HLA04303 + Undefined + - + + + C*04:48 + HLA04309 + Undefined + - + + + C*04:49 + HLA04395 + Undefined + - + + + C*04:50 + HLA04610 + Undefined + - + + + C*04:51 + HLA04611 + Undefined + - + + + C*04:52 + HLA04617 + Undefined + - + + + C*04:53 + HLA04625 + Undefined + - + + + C*04:54:01 + HLA04695 + Undefined + - + + + C*04:54:02 + HLA20468 + Undefined + - + + + C*04:55 + HLA04696 + Undefined + - + + + C*04:56 + HLA04763 + Undefined + - + + + C*04:57 + HLA04827 + Undefined + - + + + C*04:58 + HLA04838 + Undefined + - + + + C*04:59Q + HLA04841 + Undefined + - + + + C*04:60 + HLA04842 + Undefined + - + + + C*04:61N + HLA04843 + NotExpressed + Null + + + C*04:62 + HLA04851 + Undefined + - + + + C*04:63 + HLA05166 + Undefined + - + + + C*04:64:01 + HLA05167 + Undefined + - + + + C*04:64:02 + HLA08223 + Undefined + - + + + C*04:65:01:01 + HLA05170 + Undefined + - + + + C*04:65:01:02 + HLA24827 + Undefined + - + + + C*04:66 + HLA05175 + Undefined + - + + + C*04:67 + HLA05191 + Undefined + - + + + C*04:68 + HLA05206 + Undefined + - + + + C*04:69 + HLA05218 + Undefined + - + + + C*04:70 + HLA05414 + Undefined + - + + + C*04:71 + HLA05543 + Undefined + - + + + C*04:72 + HLA05573 + Undefined + - + + + C*04:73 + HLA05592 + Undefined + - + + + C*04:74 + HLA05597 + Undefined + - + + + C*04:75 + HLA05604 + Undefined + - + + + C*04:76 + HLA05620 + Undefined + - + + + C*04:77 + HLA05739 + Undefined + - + + + C*04:78 + HLA05745 + Undefined + - + + + C*04:79 + HLA05763 + Undefined + - + + + C*04:80 + HLA05782 + Undefined + - + + + C*04:81 + HLA05883 + Undefined + - + + + C*04:82:01 + HLA05916 + Undefined + - + + + C*04:82:02 + HLA30346 + Undefined + - + + + C*04:83 + HLA05947 + Undefined + - + + + C*04:84 + HLA06068 + Undefined + - + + + C*04:85 + HLA06385 + Undefined + - + + + C*04:86 + HLA06401 + Undefined + - + + + C*04:87 + HLA06403 + Undefined + - + + + C*04:88N + HLA06422 + NotExpressed + Null + + + C*04:89 + HLA06436 + Undefined + - + + + C*04:90 + HLA06665 + Undefined + - + + + C*04:91 + HLA06730 + Undefined + - + + + C*04:92 + HLA06737 + Undefined + - + + + C*04:93N + HLA07009 + NotExpressed + Null + + + C*04:94:01 + HLA07010 + Undefined + - + + + C*04:94:02 + HLA07244 + Undefined + - + + + C*04:95N + HLA07017 + NotExpressed + Null + + + C*04:96 + HLA07018 + Undefined + - + + + C*04:97 + HLA07019 + Undefined + - + + + C*04:98:01 + HLA07023 + Undefined + - + + + C*04:98:02 + HLA09045 + Undefined + - + + + C*04:99 + HLA07026 + Undefined + - + + + C*04:100 + HLA07030 + Undefined + - + + + C*04:101 + HLA07127 + Undefined + - + + + C*04:102 + HLA07120 + Undefined + - + + + C*04:103:01 + HLA07138 + Undefined + - + + + C*04:103:02 + HLA28142 + Undefined + - + + + C*04:104 + HLA07142 + Undefined + - + + + C*04:105N + HLA07243 + NotExpressed + Null + + + C*04:106 + HLA07359 + Undefined + - + + + C*04:107 + HLA07406 + Undefined + - + + + C*04:108 + HLA07499 + Undefined + - + + + C*04:109 + HLA07500 + Undefined + - + + + C*04:110 + HLA07501 + Undefined + - + + + C*04:111 + HLA07529 + Undefined + - + + + C*04:112 + HLA07755 + Undefined + - + + + C*04:113 + HLA07970 + Undefined + - + + + C*04:114 + HLA07971 + Undefined + - + + + C*04:115N + HLA07972 + NotExpressed + Null + + + C*04:116 + HLA07974 + Undefined + - + + + C*04:117 + HLA07975 + Undefined + - + + + C*04:118 + HLA08022 + Undefined + - + + + C*04:119 + HLA08119 + Undefined + - + + + C*04:120 + HLA08171 + Undefined + - + + + C*04:121 + HLA08172 + Undefined + - + + + C*04:122 + HLA08173 + Undefined + - + + + C*04:123N + HLA08174 + NotExpressed + Null + + + C*04:124 + HLA08221 + Undefined + - + + + C*04:125 + HLA08222 + Undefined + - + + + C*04:126 + HLA08224 + Undefined + - + + + C*04:127 + HLA08227 + Undefined + - + + + C*04:128 + HLA08413 + Undefined + - + + + C*04:129 + HLA08441 + Undefined + - + + + C*04:130 + HLA08542 + Undefined + - + + + C*04:131 + HLA08543 + Undefined + - + + + C*04:132 + HLA08544 + Undefined + - + + + C*04:133 + HLA08822 + Undefined + - + + + C*04:134 + HLA08823 + Undefined + - + + + C*04:135 + HLA08825 + Undefined + - + + + C*04:136 + HLA08828 + Undefined + - + + + C*04:137 + HLA08829 + Undefined + - + + + C*04:138 + HLA08830 + Undefined + - + + + C*04:139 + HLA08832 + Undefined + - + + + C*04:140 + HLA09043 + Undefined + - + + + C*04:141 + HLA09046 + Undefined + - + + + C*04:142 + HLA09047 + Undefined + - + + + C*04:143 + HLA09049 + Undefined + - + + + C*04:144 + HLA09076 + Undefined + - + + + C*04:145 + HLA09176 + Undefined + - + + + C*04:146 + HLA09502 + Undefined + - + + + C*04:147 + HLA09617 + Undefined + - + + + C*04:148 + HLA09628 + Undefined + - + + + C*04:149 + HLA09629 + Undefined + - + + + C*04:150 + HLA09630 + Undefined + - + + + C*04:151 + HLA09632 + Undefined + - + + + C*04:152 + HLA09728 + Undefined + - + + + C*04:153 + HLA09907 + Undefined + - + + + C*04:154 + HLA09992 + Undefined + - + + + C*04:155 + HLA10109 + Undefined + - + + + C*04:156 + HLA10110 + Undefined + - + + + C*04:157 + HLA10111 + Undefined + - + + + C*04:158 + HLA10170 + Undefined + - + + + C*04:159 + HLA10197 + Undefined + - + + + C*04:160:01 + HLA10251 + Undefined + - + + + C*04:160:02 + HLA30562 + Undefined + - + + + C*04:161 + HLA10255 + Undefined + - + + + C*04:162 + HLA10525 + Undefined + - + + + C*04:163 + HLA10537 + Undefined + - + + + C*04:164:01 + HLA10597 + Undefined + - + + + C*04:164:02 + HLA18655 + Undefined + - + + + C*04:165 + HLA10600 + Undefined + - + + + C*04:166:01 + HLA11120 + Undefined + - + + + C*04:166:02 + HLA20514 + Undefined + - + + + C*04:166:03 + HLA30565 + Undefined + - + + + C*04:167 + HLA11270 + Undefined + - + + + C*04:168 + HLA11271 + Undefined + - + + + C*04:169 + HLA11345 + Undefined + - + + + C*04:170N + HLA11346 + NotExpressed + Null + + + C*04:171 + HLA11573 + Undefined + - + + + C*04:172 + HLA11583 + Undefined + - + + + C*04:173N + HLA11670 + NotExpressed + Null + + + C*04:174 + HLA11876 + Undefined + - + + + C*04:175 + HLA11877 + Undefined + - + + + C*04:176 + HLA12089 + Undefined + - + + + C*04:177 + HLA12149 + Undefined + - + + + C*04:178 + HLA12203 + Undefined + - + + + C*04:179 + HLA12346 + Undefined + - + + + C*04:180:01 + HLA12347 + Undefined + - + + + C*04:180:02 + HLA13806 + Undefined + - + + + C*04:181 + HLA12349 + Undefined + - + + + C*04:182 + HLA12513 + Undefined + - + + + C*04:183 + HLA12514 + Undefined + - + + + C*04:184 + HLA12515 + Undefined + - + + + C*04:185 + HLA12516 + Undefined + - + + + C*04:186 + HLA12702 + Undefined + - + + + C*04:187 + HLA12704 + Undefined + - + + + C*04:188 + HLA12714 + Undefined + - + + + C*04:189 + HLA12733 + Undefined + - + + + C*04:190 + HLA12744 + Undefined + - + + + C*04:191N + HLA12728 + NotExpressed + Null + + + C*04:192 + HLA12790 + Undefined + - + + + C*04:193 + HLA12791 + Undefined + - + + + C*04:194 + HLA12792 + Undefined + - + + + C*04:195 + HLA12912 + Undefined + - + + + C*04:196 + HLA13266 + Undefined + - + + + C*04:197 + HLA13268 + Undefined + - + + + C*04:198 + HLA13421 + Undefined + - + + + C*04:199 + HLA13422 + Undefined + - + + + C*04:200 + HLA13426 + Undefined + - + + + C*04:201:01 + HLA13515 + Undefined + - + + + C*04:201:02 + HLA18568 + Undefined + - + + + C*04:202:01 + HLA13672 + Undefined + - + + + C*04:202:02 + HLA37584 + Undefined + - + + + C*04:203N + HLA13673 + NotExpressed + Null + + + C*04:204 + HLA13674 + Undefined + - + + + C*04:205N + HLA13675 + NotExpressed + Null + + + C*04:206 + HLA13676 + Undefined + - + + + C*04:207 + HLA13805 + Undefined + - + + + C*04:208 + HLA13807 + Undefined + - + + + C*04:209 + HLA13808 + Undefined + - + + + C*04:210 + HLA13878 + Undefined + - + + + C*04:211 + HLA13879 + Undefined + - + + + C*04:212 + HLA13783 + Undefined + - + + + C*04:213 + HLA14031 + Undefined + - + + + C*04:214 + HLA14032 + Undefined + - + + + C*04:215N + HLA14033 + NotExpressed + Null + + + C*04:216 + HLA14034 + Undefined + - + + + C*04:217N + HLA14110 + NotExpressed + Null + + + C*04:218 + HLA14263 + Undefined + - + + + C*04:219 + HLA14264 + Undefined + - + + + C*04:220 + HLA14320 + Undefined + - + + + C*04:221 + HLA14340 + Undefined + - + + + C*04:222 + HLA14341 + Undefined + - + + + C*04:223:01 + HLA14342 + Undefined + - + + + C*04:223:02 + HLA15675 + Undefined + - + + + C*04:224 + HLA14343 + Undefined + - + + + C*04:225N + HLA14344 + NotExpressed + Null + + + C*04:226 + HLA14220 + Undefined + - + + + C*04:227 + HLA14542 + Undefined + - + + + C*04:228 + HLA14543 + Undefined + - + + + C*04:229:01 + HLA14544 + Undefined + - + + + C*04:229:02 + HLA38720 + Undefined + - + + + C*04:230 + HLA14545 + Undefined + - + + + C*04:231 + HLA14757 + Undefined + - + + + C*04:232 + HLA14758 + Undefined + - + + + C*04:233N + HLA14818 + NotExpressed + Null + + + C*04:234N + HLA15142 + NotExpressed + Null + + + C*04:235 + HLA15059 + Undefined + - + + + C*04:236N + HLA15144 + NotExpressed + Null + + + C*04:237 + HLA15123 + Undefined + - + + + C*04:238 + HLA14994 + Undefined + - + + + C*04:239 + HLA14997 + Undefined + - + + + C*04:240 + HLA15312 + Undefined + - + + + C*04:241 + HLA15313 + Undefined + - + + + C*04:242 + HLA15314 + Undefined + - + + + C*04:243 + HLA15177 + Undefined + - + + + C*04:244 + HLA15182 + Undefined + - + + + C*04:245 + HLA15425 + Undefined + - + + + C*04:246 + HLA15428 + Undefined + - + + + C*04:247 + HLA15398 + Undefined + - + + + C*04:248 + HLA15413 + Undefined + - + + + C*04:249 + HLA15672 + Undefined + - + + + C*04:250 + HLA15673 + Undefined + - + + + C*04:251 + HLA15674 + Undefined + - + + + C*04:252 + HLA15676 + Undefined + - + + + C*04:253N + HLA15677 + NotExpressed + Null + + + C*04:254 + HLA15678 + Undefined + - + + + C*04:255N + HLA15623 + NotExpressed + Null + + + C*04:256 + HLA15905 + Undefined + - + + + C*04:257 + HLA15990 + Undefined + - + + + C*04:258 + HLA16553 + Undefined + - + + + C*04:259 + HLA16554 + Undefined + - + + + C*04:260 + HLA16555 + Undefined + - + + + C*04:261 + HLA16556 + Undefined + - + + + C*04:262 + HLA16557 + Undefined + - + + + C*04:263 + HLA16558 + Undefined + - + + + C*04:264 + HLA16771 + Undefined + - + + + C*04:265 + HLA16772 + Undefined + - + + + C*04:266 + HLA16773 + Undefined + - + + + C*04:267 + HLA16729 + Undefined + - + + + C*04:268 + HLA16730 + Undefined + - + + + C*04:269 + HLA16950 + Undefined + - + + + C*04:270 + HLA16951 + Undefined + - + + + C*04:271 + HLA16952 + Undefined + - + + + C*04:272 + HLA17021 + Undefined + - + + + C*04:273 + HLA17022 + Undefined + - + + + C*04:274 + HLA17270 + Undefined + - + + + C*04:275:01:01 + HLA17276 + Undefined + - + + + C*04:275:01:02 + HLA32698 + Undefined + - + + + C*04:276 + HLA17323 + Undefined + - + + + C*04:277 + HLA17456 + Undefined + - + + + C*04:278 + HLA17517 + Undefined + - + + + C*04:279N + HLA17518 + NotExpressed + Null + + + C*04:280 + HLA17749 + Undefined + - + + + C*04:281 + HLA17900 + Undefined + - + + + C*04:282 + HLA17901 + Undefined + - + + + C*04:283 + HLA17902 + Undefined + - + + + C*04:284 + HLA17903 + Undefined + - + + + C*04:285 + HLA18050 + Undefined + - + + + C*04:286 + HLA18075 + Undefined + - + + + C*04:287 + HLA18234 + Undefined + - + + + C*04:288 + HLA18277 + Undefined + - + + + C*04:289 + HLA18402 + Undefined + - + + + C*04:290 + HLA18467 + Undefined + - + + + C*04:291 + HLA18499 + Undefined + - + + + C*04:292 + HLA18510 + Undefined + - + + + C*04:293 + HLA18525 + Undefined + - + + + C*04:294 + HLA19207 + Undefined + - + + + C*04:295 + HLA19407 + Undefined + - + + + C*04:296 + HLA19436 + Undefined + - + + + C*04:297 + HLA19562 + Undefined + - + + + C*04:298 + HLA19242 + Undefined + - + + + C*04:299 + HLA19579 + Undefined + - + + + C*04:300N + HLA19659 + NotExpressed + Null + + + C*04:301 + HLA19900 + Undefined + - + + + C*04:302 + HLA19914 + Undefined + - + + + C*04:303 + HLA19875 + Undefined + - + + + C*04:304:01 + HLA19666 + Undefined + - + + + C*04:304:02:01 + HLA27172 + Undefined + - + + + C*04:304:02:02 + HLA30516 + Undefined + - + + + C*04:305N + HLA19868 + NotExpressed + Null + + + C*04:306 + HLA19752 + Undefined + - + + + C*04:307 + HLA19863 + Undefined + - + + + C*04:308 + HLA19797 + Undefined + - + + + C*04:309N + HLA20501 + NotExpressed + Null + + + C*04:310 + HLA20112 + Undefined + - + + + C*04:311 + HLA20392 + Undefined + - + + + C*04:312 + HLA20287 + Undefined + - + + + C*04:313:01:01 + HLA20059 + Undefined + - + + + C*04:313:01:02 + HLA20800 + Undefined + - + + + C*04:314 + HLA20219 + Undefined + - + + + C*04:315 + HLA20303 + Undefined + - + + + C*04:316 + HLA20096 + Undefined + - + + + C*04:317 + HLA20426 + Undefined + - + + + C*04:318 + HLA20482 + Undefined + - + + + C*04:319 + HLA20176 + Undefined + - + + + C*04:320 + HLA20133 + Undefined + - + + + C*04:321 + HLA20191 + Undefined + - + + + C*04:322 + HLA20152 + Undefined + - + + + C*04:323 + HLA20060 + Undefined + - + + + C*04:324 + HLA20292 + Undefined + - + + + C*04:325 + HLA20041 + Undefined + - + + + C*04:326 + HLA20108 + Undefined + - + + + C*04:327 + HLA20242 + Undefined + - + + + C*04:328:01 + HLA20110 + Undefined + - + + + C*04:328:02 + HLA24231 + Undefined + - + + + C*04:329 + HLA20359 + Undefined + - + + + C*04:330 + HLA20282 + Undefined + - + + + C*04:331 + HLA20489 + Undefined + - + + + C*04:332 + HLA20232 + Undefined + - + + + C*04:333 + HLA20099 + Undefined + - + + + C*04:334 + HLA20377 + Undefined + - + + + C*04:335 + HLA20893 + Undefined + - + + + C*04:336 + HLA20713 + Undefined + - + + + C*04:337 + HLA20735 + Undefined + - + + + C*04:338Q + HLA20860 + Undefined + - + + + C*04:339:01 + HLA20676 + Undefined + - + + + C*04:339:02 + HLA21704 + Undefined + - + + + C*04:340 + HLA21064 + Undefined + - + + + C*04:341 + HLA20918 + Undefined + - + + + C*04:342 + HLA20837 + Undefined + - + + + C*04:343 + HLA20999 + Undefined + - + + + C*04:344 + HLA20968 + Undefined + - + + + C*04:345 + HLA20712 + Undefined + - + + + C*04:346 + HLA20613 + Undefined + - + + + C*04:347 + HLA21352 + Undefined + - + + + C*04:348 + HLA21530 + Undefined + - + + + C*04:349N + HLA21609 + NotExpressed + Null + + + C*04:350N + HLA21678 + NotExpressed + Null + + + C*04:351:01 + HLA21896 + Undefined + - + + + C*04:351:02 + HLA22449 + Undefined + - + + + C*04:352 + HLA21673 + Undefined + - + + + C*04:353 + HLA21748 + Undefined + - + + + C*04:354 + HLA21897 + Undefined + - + + + C*04:355 + HLA21754 + Undefined + - + + + C*04:356 + HLA21874 + Undefined + - + + + C*04:357 + HLA21885 + Undefined + - + + + C*04:358 + HLA21745 + Undefined + - + + + C*04:359 + HLA21906 + Undefined + - + + + C*04:360 + HLA22100 + Undefined + - + + + C*04:361 + HLA21998 + Undefined + - + + + C*04:362N + HLA22038 + NotExpressed + Null + + + C*04:363 + HLA22057 + Undefined + - + + + C*04:364N + HLA22465 + NotExpressed + Null + + + C*04:365N + HLA22357 + NotExpressed + Null + + + C*04:366 + HLA22333 + Undefined + - + + + C*04:367 + HLA22308 + Undefined + - + + + C*04:368 + HLA22581 + Undefined + - + + + C*04:369N + HLA22224 + NotExpressed + Null + + + C*04:370 + HLA22372 + Undefined + - + + + C*04:371N + HLA22272 + NotExpressed + Null + + + C*04:372 + HLA22488 + Undefined + - + + + C*04:373 + HLA22337 + Undefined + - + + + C*04:374N + HLA22667 + NotExpressed + Null + + + C*04:375 + HLA22752 + Undefined + - + + + C*04:376 + HLA22940 + Undefined + - + + + C*04:377N + HLA23310 + NotExpressed + Null + + + C*04:378 + HLA23599 + Undefined + - + + + C*04:379 + HLA23793 + Undefined + - + + + C*04:380 + HLA23769 + Undefined + - + + + C*04:381 + HLA23159 + Undefined + - + + + C*04:382Q + HLA23722 + Undefined + - + + + C*04:383 + HLA23355 + Undefined + - + + + C*04:384 + HLA23273 + Undefined + - + + + C*04:385N + HLA23040 + NotExpressed + Null + + + C*04:386 + HLA23293 + Undefined + - + + + C*04:387 + HLA24255 + Undefined + - + + + C*04:388 + HLA23869 + Undefined + - + + + C*04:389 + HLA23921 + Undefined + - + + + C*04:390 + HLA23944 + Undefined + - + + + C*04:391 + HLA24013 + Undefined + - + + + C*04:392 + HLA24128 + Undefined + - + + + C*04:393 + HLA23906 + Undefined + - + + + C*04:394 + HLA24293 + Undefined + - + + + C*04:395 + HLA24087 + Undefined + - + + + C*04:396N + HLA23892 + NotExpressed + Null + + + C*04:397 + HLA24222 + Undefined + - + + + C*04:398 + HLA24082 + Undefined + - + + + C*04:399 + HLA24616 + Undefined + - + + + C*04:400 + HLA25085 + Undefined + - + + + C*04:401 + HLA25881 + Undefined + - + + + C*04:402 + HLA25717 + Undefined + - + + + C*04:403 + HLA25666 + Undefined + - + + + C*04:404 + HLA26008 + Undefined + - + + + C*04:405 + HLA26165 + Undefined + - + + + C*04:406 + HLA26310 + Undefined + - + + + C*04:407 + HLA26227 + Undefined + - + + + C*04:408 + HLA26269 + Undefined + - + + + C*04:409 + HLA26872 + Undefined + - + + + C*04:410N + HLA27118 + NotExpressed + Null + + + C*04:411N + HLA27139 + NotExpressed + Null + + + C*04:412 + HLA27182 + Undefined + - + + + C*04:413 + HLA27187 + Undefined + - + + + C*04:414 + HLA27821 + Undefined + - + + + C*04:415 + HLA27842 + Undefined + - + + + C*04:416 + HLA27849 + Undefined + - + + + C*04:417N + HLA27850 + NotExpressed + Null + + + C*04:418 + HLA27869 + Undefined + - + + + C*04:419 + HLA27928 + Undefined + - + + + C*04:420 + HLA28140 + Undefined + - + + + C*04:421 + HLA28145 + Undefined + - + + + C*04:422 + HLA28173 + Undefined + - + + + C*04:423 + HLA28092 + Undefined + - + + + C*04:424 + HLA28106 + Undefined + - + + + C*04:425 + HLA28275 + Undefined + - + + + C*04:426 + HLA28279 + Undefined + - + + + C*04:427 + HLA28288 + Undefined + - + + + C*04:428Q + HLA28371 + Undefined + - + + + C*04:429 + HLA28499 + Undefined + - + + + C*04:430 + HLA28578 + Undefined + - + + + C*04:431 + HLA28792 + Undefined + - + + + C*04:432 + HLA28822 + Undefined + - + + + C*04:433 + HLA29159 + Undefined + - + + + C*04:434 + HLA29178 + Undefined + - + + + C*04:435 + HLA29264 + Undefined + - + + + C*04:436N + HLA29472 + NotExpressed + Null + + + C*04:437 + HLA29854 + Undefined + - + + + C*04:438 + HLA30176 + Undefined + - + + + C*04:439 + HLA30037 + Undefined + - + + + C*04:440 + HLA30725 + Undefined + - + + + C*04:441:01:01 + HLA30506 + Undefined + - + + + C*04:441:01:02 + HLA33914 + Undefined + - + + + C*04:442 + HLA30603 + Undefined + - + + + C*04:443 + HLA30848 + Undefined + - + + + C*04:444 + HLA31158 + Undefined + - + + + C*04:445 + HLA31243 + Undefined + - + + + C*04:446 + HLA31329 + Undefined + - + + + C*04:447 + HLA31360 + Undefined + - + + + C*04:448 + HLA31138 + Undefined + - + + + C*04:449 + HLA31409 + Undefined + - + + + C*04:450 + HLA31438 + Undefined + - + + + C*04:451 + HLA31742 + Undefined + - + + + C*04:452N + HLA31631 + NotExpressed + Null + + + C*04:453 + HLA31534 + Undefined + - + + + C*04:454 + HLA31643 + Undefined + - + + + C*04:455 + HLA31519 + Undefined + - + + + C*04:456Q + HLA31699 + Undefined + - + + + C*04:457 + HLA32072 + Undefined + - + + + C*04:458 + HLA32031 + Undefined + - + + + C*04:459 + HLA32103 + Undefined + - + + + C*04:460 + HLA33133 + Undefined + - + + + C*04:461 + HLA33573 + Undefined + - + + + C*04:462 + HLA33623 + Undefined + - + + + C*04:463 + HLA33547 + Undefined + - + + + C*04:464 + HLA33605 + Undefined + - + + + C*04:465 + HLA33672 + Undefined + - + + + C*04:466 + HLA33525 + Undefined + - + + + C*04:467 + HLA33527 + Undefined + - + + + C*04:468 + HLA33680 + Undefined + - + + + C*04:469 + HLA33772 + Undefined + - + + + C*04:470 + HLA33954 + Undefined + - + + + C*04:471 + HLA34042 + Undefined + - + + + C*04:472 + HLA34187 + Undefined + - + + + C*04:473 + HLA34429 + Undefined + - + + + C*04:474 + HLA34370 + Undefined + - + + + C*04:475 + HLA34307 + Undefined + - + + + C*04:476 + HLA34814 + Undefined + - + + + C*04:477 + HLA35029 + Undefined + - + + + C*04:478 + HLA35356 + Undefined + - + + + C*04:479 + HLA35087 + Undefined + - + + + C*04:480 + HLA35247 + Undefined + - + + + C*04:481 + HLA34819 + Undefined + - + + + C*04:482 + HLA35078 + Undefined + - + + + C*04:483 + HLA35173 + Undefined + - + + + C*04:484 + HLA35254 + Undefined + - + + + C*04:485 + HLA34815 + Undefined + - + + + C*04:486N + HLA34891 + NotExpressed + Null + + + C*04:487 + HLA35475 + Undefined + - + + + C*04:488 + HLA35604 + Undefined + - + + + C*04:489 + HLA35845 + Undefined + - + + + C*04:490 + HLA36284 + Undefined + - + + + C*04:491 + HLA36745 + Undefined + - + + + C*04:492 + HLA36617 + Undefined + - + + + C*04:493 + HLA36924 + Undefined + - + + + C*04:494 + HLA36884 + Undefined + - + + + C*04:495 + HLA36962 + Undefined + - + + + C*04:496 + HLA37002 + Undefined + - + + + C*04:497 + HLA37073 + Undefined + - + + + C*04:498N + HLA37081 + NotExpressed + Null + + + C*04:499 + HLA37129 + Undefined + - + + + C*04:500 + HLA37115 + Undefined + - + + + C*04:501:01:01 + HLA37108 + Undefined + - + + + C*04:501:01:02 + HLA37205 + Undefined + - + + + C*04:502 + HLA37313 + Undefined + - + + + C*04:503Q + HLA37549 + Undefined + - + + + C*04:504 + HLA37653 + Undefined + - + + + C*04:505 + HLA37735 + Undefined + - + + + C*04:506 + HLA37825 + Undefined + - + + + C*04:507 + HLA37708 + Undefined + - + + + C*04:508 + HLA38503 + Undefined + - + + + C*04:509N + HLA38436 + NotExpressed + Null + + + C*04:510 + HLA38726 + Undefined + - + + + C*05:01:01:01 + HLA00427 + Cw5 + Cw5 + + + C*05:01:01:02 + HLA03586 + Cw5 + Cw5 + + + C*05:01:01:03 + HLA15495 + Cw5 + Cw5 + + + C*05:01:01:04 + HLA15770 + Cw5 + Cw5 + + + C*05:01:01:05 + HLA15772 + Cw5 + Cw5 + + + C*05:01:01:06 + HLA16714 + Cw5 + Cw5 + + + C*05:01:01:07 + HLA16715 + Cw5 + Cw5 + + + C*05:01:01:08 + HLA17049 + Cw5 + Cw5 + + + C*05:01:01:09 + HLA17633 + Cw5 + Cw5 + + + C*05:01:01:10 + HLA19058 + Cw5 + Cw5 + + + C*05:01:01:11 + HLA19139 + Cw5 + Cw5 + + + C*05:01:01:12 + HLA19092 + Cw5 + Cw5 + + + C*05:01:01:13 + HLA19533 + Cw5 + Cw5 + + + C*05:01:01:14 + HLA19225 + Cw5 + Cw5 + + + C*05:01:01:15 + HLA20088 + Cw5 + Cw5 + + + C*05:01:01:16 + HLA21364 + Cw5 + Cw5 + + + C*05:01:01:17 + HLA22741 + Cw5 + Cw5 + + + C*05:01:01:18 + HLA24847 + Cw5 + Cw5 + + + C*05:01:01:19 + HLA25037 + Cw5 + Cw5 + + + C*05:01:01:20 + HLA24832 + Cw5 + Cw5 + + + C*05:01:01:21 + HLA24726 + Cw5 + Cw5 + + + C*05:01:01:22 + HLA25340 + Cw5 + Cw5 + + + C*05:01:01:23 + HLA24428 + Cw5 + Cw5 + + + C*05:01:01:24 + HLA24484 + Cw5 + Cw5 + + + C*05:01:01:25 + HLA24977 + Cw5 + Cw5 + + + C*05:01:01:26 + HLA25442 + Cw5 + Cw5 + + + C*05:01:01:27 + HLA25515 + Cw5 + Cw5 + + + C*05:01:01:28 + HLA24490 + Cw5 + Cw5 + + + C*05:01:01:29 + HLA25551 + Cw5 + Cw5 + + + C*05:01:01:30 + HLA25147 + Cw5 + Cw5 + + + C*05:01:01:31 + HLA24848 + Cw5 + Cw5 + + + C*05:01:01:32 + HLA25339 + Cw5 + Cw5 + + + C*05:01:01:33 + HLA25392 + Cw5 + Cw5 + + + C*05:01:01:34 + HLA25198 + Cw5 + Cw5 + + + C*05:01:01:35 + HLA24540 + Cw5 + Cw5 + + + C*05:01:01:36 + HLA25757 + Cw5 + Cw5 + + + C*05:01:01:37 + HLA26009 + Cw5 + Cw5 + + + C*05:01:01:38 + HLA25715 + Cw5 + Cw5 + + + C*05:01:01:39 + HLA25789 + Cw5 + Cw5 + + + C*05:01:01:40 + HLA25622 + Cw5 + Cw5 + + + C*05:01:01:41 + HLA27123 + Cw5 + Cw5 + + + C*05:01:01:42 + HLA27140 + Cw5 + Cw5 + + + C*05:01:01:43 + HLA27161 + Cw5 + Cw5 + + + C*05:01:01:44 + HLA27241 + Cw5 + Cw5 + + + C*05:01:01:45 + HLA27252 + Cw5 + Cw5 + + + C*05:01:01:46 + HLA27253 + Cw5 + Cw5 + + + C*05:01:01:47 + HLA27892 + Cw5 + Cw5 + + + C*05:01:01:48 + HLA27841 + Cw5 + Cw5 + + + C*05:01:01:49 + HLA28137 + Cw5 + Cw5 + + + C*05:01:01:50 + HLA28473 + Cw5 + Cw5 + + + C*05:01:01:51 + HLA29055 + Cw5 + Cw5 + + + C*05:01:01:52 + HLA29405 + Cw5 + Cw5 + + + C*05:01:01:53Q + HLA29456 + Undefined + - + + + C*05:01:01:54 + HLA30495 + Cw5 + Cw5 + + + C*05:01:01:55 + HLA31948 + Cw5 + Cw5 + + + C*05:01:01:56 + HLA32585 + Cw5 + Cw5 + + + C*05:01:01:57 + HLA33364 + Cw5 + Cw5 + + + C*05:01:01:58 + HLA32709 + Cw5 + Cw5 + + + C*05:01:01:59 + HLA32939 + Cw5 + Cw5 + + + C*05:01:01:60 + HLA32878 + Cw5 + Cw5 + + + C*05:01:01:61 + HLA33203 + Cw5 + Cw5 + + + C*05:01:01:62 + HLA33144 + Cw5 + Cw5 + + + C*05:01:01:63 + HLA32984 + Cw5 + Cw5 + + + C*05:01:01:64 + HLA32739 + Cw5 + Cw5 + + + C*05:01:01:65 + HLA33172 + Cw5 + Cw5 + + + C*05:01:01:66 + HLA32813 + Cw5 + Cw5 + + + C*05:01:01:67 + HLA32639 + Cw5 + Cw5 + + + C*05:01:01:68 + HLA32810 + Cw5 + Cw5 + + + C*05:01:01:69 + HLA32843 + Cw5 + Cw5 + + + C*05:01:01:70 + HLA33296 + Cw5 + Cw5 + + + C*05:01:01:71 + HLA33395 + Cw5 + Cw5 + + + C*05:01:01:72 + HLA33083 + Cw5 + Cw5 + + + C*05:01:01:73 + HLA32884 + Cw5 + Cw5 + + + C*05:01:01:74 + HLA33213 + Cw5 + Cw5 + + + C*05:01:01:75 + HLA33137 + Cw5 + Cw5 + + + C*05:01:01:76 + HLA32817 + Cw5 + Cw5 + + + C*05:01:01:77 + HLA32703 + Cw5 + Cw5 + + + C*05:01:01:78 + HLA33412 + Cw5 + Cw5 + + + C*05:01:01:79 + HLA32646 + Cw5 + Cw5 + + + C*05:01:01:80Q + HLA33696 + Undefined + - + + + C*05:01:01:81Q + HLA34354 + Undefined + - + + + C*05:01:01:82 + HLA38124 + Cw5 + Cw5 + + + C*05:01:01:83 + HLA38218 + Cw5 + Cw5 + + + C*05:01:01:84 + HLA38144 + Cw5 + Cw5 + + + C*05:01:01:85 + HLA38517 + Cw5 + Cw5 + + + C*05:01:02 + HLA01998 + Cw5 + Cw5 + + + C*05:01:03 + HLA02292 + Cw5 + Cw5 + + + C*05:01:04 + HLA03191 + Cw5 + Cw5 + + + C*05:01:05 + HLA03978 + Cw5 + Cw5 + + + C*05:01:06 + HLA04133 + Cw5 + Cw5 + + + C*05:01:07 + HLA04293 + Cw5 + Cw5 + + + C*05:01:08 + HLA04296 + Cw5 + Cw5 + + + C*05:01:09 + HLA04305 + Cw5 + Cw5 + + + C*05:01:10 + HLA04306 + Cw5 + Cw5 + + + C*05:01:11 + HLA04391 + Cw5 + Cw5 + + + C*05:01:12 + HLA04798 + Cw5 + Cw5 + + + C*05:01:13 + HLA04800 + Cw5 + Cw5 + + + C*05:01:14 + HLA05572 + Cw5 + Cw5 + + + C*05:01:15 + HLA05880 + Cw5 + Cw5 + + + C*05:01:16 + HLA06411 + Cw5 + Cw5 + + + C*05:01:17 + HLA07011 + Cw5 + Cw5 + + + C*05:01:18 + HLA07226 + Cw5 + Cw5 + + + C*05:01:19 + HLA07976 + Cw5 + Cw5 + + + C*05:01:20 + HLA07979 + Cw5 + Cw5 + + + C*05:01:21 + HLA08156 + Cw5 + Cw5 + + + C*05:01:22 + HLA08475 + Cw5 + Cw5 + + + C*05:01:23 + HLA08532 + Cw5 + Cw5 + + + C*05:01:24 + HLA08730 + Cw5 + Cw5 + + + C*05:01:25 + HLA08732 + Cw5 + Cw5 + + + C*05:01:26 + HLA09034 + Cw5 + Cw5 + + + C*05:01:27 + HLA09609 + Cw5 + Cw5 + + + C*05:01:28 + HLA12187 + Cw5 + Cw5 + + + C*05:01:29 + HLA12200 + Cw5 + Cw5 + + + C*05:01:30 + HLA12332 + Cw5 + Cw5 + + + C*05:01:31 + HLA12743 + Cw5 + Cw5 + + + C*05:01:32 + HLA15130 + Cw5 + Cw5 + + + C*05:01:33 + HLA15426 + Cw5 + Cw5 + + + C*05:01:34 + HLA15883 + Cw5 + Cw5 + + + C*05:01:35 + HLA17416 + Cw5 + Cw5 + + + C*05:01:36 + HLA17637 + Cw5 + Cw5 + + + C*05:01:37 + HLA18458 + Cw5 + Cw5 + + + C*05:01:38 + HLA18484 + Cw5 + Cw5 + + + C*05:01:39 + HLA18852 + Cw5 + Cw5 + + + C*05:01:40 + HLA20118 + Cw5 + Cw5 + + + C*05:01:41 + HLA20166 + Cw5 + Cw5 + + + C*05:01:42 + HLA20167 + Cw5 + Cw5 + + + C*05:01:43 + HLA20319 + Cw5 + Cw5 + + + C*05:01:44 + HLA20847 + Cw5 + Cw5 + + + C*05:01:45 + HLA21773 + Cw5 + Cw5 + + + C*05:01:46 + HLA23756 + Cw5 + Cw5 + + + C*05:01:47 + HLA23646 + Cw5 + Cw5 + + + C*05:01:48 + HLA23886 + Cw5 + Cw5 + + + C*05:01:49 + HLA24421 + Cw5 + Cw5 + + + C*05:01:50 + HLA26118 + Cw5 + Cw5 + + + C*05:01:51 + HLA26256 + Cw5 + Cw5 + + + C*05:01:52 + HLA27583 + Cw5 + Cw5 + + + C*05:01:53 + HLA28156 + Cw5 + Cw5 + + + C*05:01:54 + HLA28264 + Cw5 + Cw5 + + + C*05:01:55 + HLA28265 + Cw5 + Cw5 + + + C*05:01:56 + HLA28372 + Cw5 + Cw5 + + + C*05:01:57 + HLA29520 + Cw5 + Cw5 + + + C*05:01:58 + HLA29866 + Cw5 + Cw5 + + + C*05:01:59 + HLA30043 + Cw5 + Cw5 + + + C*05:01:60 + HLA30003 + Cw5 + Cw5 + + + C*05:01:61 + HLA29986 + Cw5 + Cw5 + + + C*05:01:62 + HLA29966 + Cw5 + Cw5 + + + C*05:01:63 + HLA30751 + Cw5 + Cw5 + + + C*05:01:64 + HLA30555 + Cw5 + Cw5 + + + C*05:01:65 + HLA30984 + Cw5 + Cw5 + + + C*05:01:66 + HLA31459 + Cw5 + Cw5 + + + C*05:01:67 + HLA32049 + Cw5 + Cw5 + + + C*05:01:68 + HLA32200 + Cw5 + Cw5 + + + C*05:01:69 + HLA33495 + Cw5 + Cw5 + + + C*05:01:70 + HLA34551 + Cw5 + Cw5 + + + C*05:01:71 + HLA35265 + Cw5 + Cw5 + + + C*05:01:72 + HLA35670 + Cw5 + Cw5 + + + C*05:01:73 + HLA37028 + Cw5 + Cw5 + + + C*05:01:74 + HLA37095 + Cw5 + Cw5 + + + C*05:01:75 + HLA37896 + Cw5 + Cw5 + + + C*05:03 + HLA01169 + Cw5 + - + + + C*05:04:01 + HLA01174 + Cw5 + - + + + C*05:04:02 + HLA08736 + Cw5 + - + + + C*05:05:01 + HLA01602 + Cw5 + - + + + C*05:05:02 + HLA15945 + Cw5 + - + + + C*05:06 + HLA01661 + Cw5 + - + + + C*05:07N + HLA01832 + NotExpressed + Null + + + C*05:08 + HLA01843 + Cw5 + - + + + C*05:09:01 + HLA01856 + Cw5 + - + + + C*05:09:02 + HLA07122 + Cw5 + - + + + C*05:09:03 + HLA12042 + Cw5 + - + + + C*05:10 + HLA01907 + Cw5 + - + + + C*05:11 + HLA02148 + Cw5 + - + + + C*05:12 + HLA02397 + Cw5 + - + + + C*05:13 + HLA02408 + Cw5 + - + + + C*05:14 + HLA02586 + Cw5 + - + + + C*05:15 + HLA02753 + Cw5 + - + + + C*05:16 + HLA02785 + Cw5 + - + + + C*05:17 + HLA02979 + Cw5 + - + + + C*05:18:01 + HLA03212 + Undefined + - + + + C*05:18:02 + HLA07028 + Undefined + - + + + C*05:18:03 + HLA07031 + Undefined + - + + + C*05:18:04 + HLA15947 + Undefined + - + + + C*05:18:05 + HLA21718 + Undefined + - + + + C*05:18:06 + HLA23773 + Undefined + - + + + C*05:19 + HLA03219 + Undefined + - + + + C*05:20 + HLA03438 + Undefined + - + + + C*05:21 + HLA03517 + Undefined + - + + + C*05:22:01 + HLA03531 + Undefined + - + + + C*05:22:02 + HLA07225 + Undefined + - + + + C*05:23 + HLA03563 + Undefined + - + + + C*05:24 + HLA03634 + Undefined + - + + + C*05:25 + HLA03681 + Undefined + - + + + C*05:26 + HLA04297 + Undefined + - + + + C*05:27 + HLA04302 + Undefined + - + + + C*05:28 + HLA04304 + Undefined + - + + + C*05:29:01 + HLA04308 + Undefined + - + + + C*05:29:02 + HLA08749 + Undefined + - + + + C*05:30 + HLA04310 + Undefined + - + + + C*05:31 + HLA04394 + Undefined + - + + + C*05:32 + HLA04587 + Undefined + - + + + C*05:33 + HLA04596 + Undefined + - + + + C*05:34 + HLA04608 + Undefined + - + + + C*05:35 + HLA04677 + Undefined + - + + + C*05:36 + HLA04701 + Undefined + - + + + C*05:37 + HLA04856 + Undefined + - + + + C*05:38 + HLA04799 + Undefined + - + + + C*05:39 + HLA04801 + Undefined + - + + + C*05:40 + HLA04802 + Undefined + - + + + C*05:41 + HLA04803 + Undefined + - + + + C*05:42 + HLA04832 + Undefined + - + + + C*05:43 + HLA05213 + Undefined + - + + + C*05:44:01 + HLA05310 + Undefined + - + + + C*05:44:02 + HLA08199 + Undefined + - + + + C*05:45 + HLA05382 + Undefined + - + + + C*05:46:01:01 + HLA05571 + Undefined + - + + + C*05:46:01:02 + HLA26271 + Undefined + - + + + C*05:47 + HLA05585 + Undefined + - + + + C*05:48N + HLA05588 + NotExpressed + Null + + + C*05:49 + HLA05593 + Undefined + - + + + C*05:50 + HLA05736 + Undefined + - + + + C*05:51Q + HLA05852 + Undefined + - + + + C*05:52 + HLA06054 + Undefined + - + + + C*05:53 + HLA06125 + Undefined + - + + + C*05:54 + HLA06382 + Undefined + - + + + C*05:55 + HLA06383 + Undefined + - + + + C*05:56 + HLA06432 + Undefined + - + + + C*05:57 + HLA06431 + Undefined + - + + + C*05:58:01 + HLA06528 + Undefined + - + + + C*05:58:02 + HLA07222 + Undefined + - + + + C*05:58:03 + HLA15178 + Undefined + - + + + C*05:58:04 + HLA21764 + Undefined + - + + + C*05:59 + HLA06720 + Undefined + - + + + C*05:60 + HLA07052 + Undefined + - + + + C*05:61 + HLA07063 + Undefined + - + + + C*05:62 + HLA07075 + Undefined + - + + + C*05:63 + HLA07082 + Undefined + - + + + C*05:64:01 + HLA07108 + Undefined + - + + + C*05:64:02 + HLA09191 + Undefined + - + + + C*05:65 + HLA07109 + Undefined + - + + + C*05:66 + HLA07111 + Undefined + - + + + C*05:67 + HLA07134 + Undefined + - + + + C*05:68 + HLA07135 + Undefined + - + + + C*05:69 + HLA07224 + Undefined + - + + + C*05:70 + HLA07227 + Undefined + - + + + C*05:71 + HLA07228 + Undefined + - + + + C*05:72 + HLA07358 + Undefined + - + + + C*05:73 + HLA07487 + Undefined + - + + + C*05:74 + HLA07488 + Undefined + - + + + C*05:75 + HLA07977 + Undefined + - + + + C*05:76 + HLA07978 + Undefined + - + + + C*05:77 + HLA07980 + Undefined + - + + + C*05:78:01 + HLA07981 + Undefined + - + + + C*05:78:02 + HLA15989 + Undefined + - + + + C*05:79 + HLA08155 + Undefined + - + + + C*05:80 + HLA08198 + Undefined + - + + + C*05:81 + HLA08200 + Undefined + - + + + C*05:82 + HLA08733 + Undefined + - + + + C*05:83 + HLA08734 + Undefined + - + + + C*05:84 + HLA08735 + Undefined + - + + + C*05:85 + HLA08737 + Undefined + - + + + C*05:86 + HLA09024 + Undefined + - + + + C*05:87 + HLA09025 + Undefined + - + + + C*05:88 + HLA09133 + Undefined + - + + + C*05:89 + HLA09189 + Undefined + - + + + C*05:90 + HLA09190 + Undefined + - + + + C*05:91N + HLA09192 + NotExpressed + Null + + + C*05:92N + HLA09518 + NotExpressed + Null + + + C*05:93 + HLA09646 + Undefined + - + + + C*05:94 + HLA09679 + Undefined + - + + + C*05:95 + HLA09965 + Undefined + - + + + C*05:96 + HLA09999 + Undefined + - + + + C*05:97 + HLA10079 + Undefined + - + + + C*05:98 + HLA10437 + Undefined + - + + + C*05:99N + HLA10664 + NotExpressed + Null + + + C*05:100 + HLA11093 + Undefined + - + + + C*05:101 + HLA11094 + Undefined + - + + + C*05:102 + HLA11464 + Undefined + - + + + C*05:103:01 + HLA11858 + Undefined + - + + + C*05:103:02 + HLA15303 + Undefined + - + + + C*05:104 + HLA12188 + Undefined + - + + + C*05:105 + HLA12405 + Undefined + - + + + C*05:106:01 + HLA12504 + Undefined + - + + + C*05:106:02 + HLA14995 + Undefined + - + + + C*05:107 + HLA12505 + Undefined + - + + + C*05:108 + HLA12591 + Undefined + - + + + C*05:109 + HLA12706 + Undefined + - + + + C*05:110 + HLA12721 + Undefined + - + + + C*05:111 + HLA12726 + Undefined + - + + + C*05:112 + HLA12742 + Undefined + - + + + C*05:113N + HLA12687 + NotExpressed + Null + + + C*05:114 + HLA12771 + Undefined + - + + + C*05:115 + HLA13097 + Undefined + - + + + C*05:116 + HLA13100 + Undefined + - + + + C*05:117 + HLA13418 + Undefined + - + + + C*05:118 + HLA13529 + Undefined + - + + + C*05:119 + HLA13562 + Undefined + - + + + C*05:120 + HLA13564 + Undefined + - + + + C*05:121 + HLA13752 + Undefined + - + + + C*05:122 + HLA13753 + Undefined + - + + + C*05:123 + HLA14026 + Undefined + - + + + C*05:124 + HLA14104 + Undefined + - + + + C*05:125 + HLA14252 + Undefined + - + + + C*05:126 + HLA14333 + Undefined + - + + + C*05:127 + HLA14533 + Undefined + - + + + C*05:128N + HLA14606 + NotExpressed + Null + + + C*05:129 + HLA14749 + Undefined + - + + + C*05:130 + HLA14896 + Undefined + - + + + C*05:131 + HLA15047 + Undefined + - + + + C*05:132 + HLA15048 + Undefined + - + + + C*05:133 + HLA15121 + Undefined + - + + + C*05:134 + HLA15181 + Undefined + - + + + C*05:135 + HLA15205 + Undefined + - + + + C*05:136 + HLA15657 + Undefined + - + + + C*05:137 + HLA15587 + Undefined + - + + + C*05:138 + HLA15744 + Undefined + - + + + C*05:139 + HLA15798 + Undefined + - + + + C*05:140 + HLA15808 + Undefined + - + + + 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C*06:02:54 + HLA18855 + Cw6 + Cw6 + + + C*06:02:55 + HLA19524 + Cw6 + Cw6 + + + C*06:02:56 + HLA19247 + Cw6 + Cw6 + + + C*06:02:57 + HLA19189 + Cw6 + Cw6 + + + C*06:02:58 + HLA19756 + Cw6 + Cw6 + + + C*06:02:59 + HLA19831 + Cw6 + Cw6 + + + C*06:02:60 + HLA19852 + Cw6 + Cw6 + + + C*06:02:61 + HLA19749 + Cw6 + Cw6 + + + C*06:02:62 + HLA19771 + Cw6 + Cw6 + + + C*06:02:63 + HLA19811 + Cw6 + Cw6 + + + C*06:02:64 + HLA19812 + Cw6 + Cw6 + + + C*06:02:65 + HLA19745 + Cw6 + Cw6 + + + C*06:02:66 + HLA20073 + Cw6 + Cw6 + + + C*06:02:67 + HLA20302 + Cw6 + Cw6 + + + C*06:02:68 + HLA20058 + Cw6 + Cw6 + + + C*06:02:69 + HLA20226 + Cw6 + Cw6 + + + C*06:02:70 + HLA21143 + Cw6 + Cw6 + + + C*06:02:71 + HLA20934 + Cw6 + Cw6 + + + C*06:02:72 + HLA23053 + Cw6 + Cw6 + + + C*06:02:73 + HLA23623 + Cw6 + Cw6 + + + C*06:02:74 + HLA23619 + Cw6 + Cw6 + + + C*06:02:75 + HLA23624 + Cw6 + Cw6 + + + C*06:02:76 + HLA23145 + Cw6 + Cw6 + + + C*06:02:77 + HLA23651 + Cw6 + Cw6 + + + C*06:02:78 + HLA23723 + Cw6 + Cw6 + + + C*06:02:79 + HLA24301 + Cw6 + Cw6 + + + C*06:02:80 + HLA23964 + Cw6 + Cw6 + + + C*06:02:81 + HLA24535 + Cw6 + Cw6 + + + C*06:02:82 + HLA25803 + Cw6 + Cw6 + + + C*06:02:83 + HLA28828 + Cw6 + Cw6 + + + C*06:02:84 + HLA28865 + Cw6 + Cw6 + + + C*06:02:85 + HLA28867 + Cw6 + Cw6 + + + C*06:02:86 + HLA29134 + Cw6 + Cw6 + + + C*06:02:87 + HLA29989 + Cw6 + Cw6 + + + C*06:02:88 + HLA29960 + Cw6 + Cw6 + + + C*06:02:89 + HLA29945 + Cw6 + Cw6 + + + C*06:02:90 + HLA29950 + Cw6 + Cw6 + + + C*06:02:91 + HLA30559 + Cw6 + Cw6 + + + C*06:02:92 + HLA30513 + Cw6 + Cw6 + + + C*06:02:93 + HLA31044 + Cw6 + Cw6 + + + C*06:02:94 + HLA31660 + Cw6 + Cw6 + + + C*06:02:95 + HLA31522 + Cw6 + Cw6 + + + C*06:02:96 + HLA32019 + Cw6 + Cw6 + + + C*06:02:97 + HLA33682 + Cw6 + Cw6 + + + C*06:02:98 + HLA33915 + Cw6 + Cw6 + + + C*06:02:99 + HLA33966 + Cw6 + Cw6 + + + C*06:02:100 + HLA34350 + Cw6 + Cw6 + + + C*06:02:101 + HLA34914 + Cw6 + Cw6 + + + C*06:02:102 + HLA35196 + Cw6 + Cw6 + + + C*06:02:103 + HLA36277 + Cw6 + Cw6 + + + C*06:02:104 + HLA36991 + Cw6 + Cw6 + + + C*06:02:105 + HLA37311 + Cw6 + Cw6 + + + C*06:02:106 + HLA37248 + Cw6 + Cw6 + + + C*06:02:107 + HLA37292 + Cw6 + Cw6 + + + C*06:02:108 + HLA37314 + Cw6 + Cw6 + + + C*06:02:109 + HLA37840 + Cw6 + Cw6 + + + C*06:02:110 + HLA37865 + Cw6 + Cw6 + + + C*06:02:111 + HLA37899 + Cw6 + Cw6 + + + C*06:03:01 + HLA00431 + Cw6 + - + + + C*06:03:02 + HLA07492 + Cw6 + - + + + C*06:04:01 + HLA00432 + Cw6 + - + + + C*06:04:02:01 + HLA13971 + Cw6 + - + + + C*06:04:02:02 + HLA28434 + Cw6 + - + + + C*06:05 + HLA00991 + Cw6 + Cw6 + + + C*06:06:01:01 + HLA01258 + Cw6 + - + + + C*06:06:01:02 + HLA28289 + Cw6 + - + + + C*06:07 + HLA01301 + Cw6 + - + + + C*06:08 + HLA01628 + Cw6 + - + + + C*06:09:01 + HLA01681 + Cw6 + - + + + C*06:09:02 + HLA19832 + Cw6 + - + + + C*06:10 + HLA01824 + Cw6 + - + + + C*06:11 + HLA01880 + Undefined + - + + + C*06:12 + HLA02178 + Cw6 + - + + + C*06:13 + HLA02239 + Cw6 + - + + + C*06:14 + HLA02708 + Cw6 + - + + + C*06:15 + HLA02832 + Cw6 + - + + + C*06:16N + HLA02833 + NotExpressed + Null + + + C*06:17 + HLA02641 + Undefined + - + + + C*06:18 + HLA03429 + Undefined + - + + + C*06:19 + HLA03526 + Undefined + - + + + C*06:20 + HLA03624 + Undefined + - + + + C*06:21 + HLA03727 + Undefined + - + + + C*06:22 + HLA03682 + Undefined + - + + + C*06:23 + HLA03697 + Undefined + - + + + C*06:24 + HLA03754 + Undefined + - + + + C*06:25 + HLA04294 + Undefined + - + + + C*06:26 + HLA04295 + Undefined + - + + + C*06:27 + HLA04299 + Undefined + - + + + C*06:28 + HLA04307 + Undefined + - + + + C*06:29 + HLA04638 + Undefined + - + + + C*06:30 + HLA04697 + Undefined + - + + + C*06:31 + HLA04700 + Undefined + - + + + C*06:32 + HLA04745 + Undefined + - + + + C*06:33 + HLA04780 + Undefined + - + + + C*06:34:01 + HLA04828 + Undefined + - + + + C*06:34:02 + HLA14020 + Undefined + - + + + C*06:35 + HLA04835 + Undefined + - + + + C*06:36 + HLA04837 + Undefined + - + + + C*06:37 + HLA04844 + Undefined + - + + + C*06:38 + HLA05164 + Undefined + - + + + C*06:39 + HLA05168 + Undefined + - + + + C*06:40 + HLA05184 + Undefined + - + + + C*06:41 + HLA05192 + Undefined + - + + + C*06:42:01 + HLA05207 + Undefined + - + + + C*06:42:02 + HLA14523 + Undefined + - + + + C*06:43:01 + HLA05385 + Undefined + - + + + C*06:43:02 + HLA09180 + Undefined + - + + + C*06:44 + HLA05397 + Undefined + - + + + C*06:45 + HLA05423 + Undefined + - + + + C*06:46N + HLA05526 + NotExpressed + Null + + + C*06:47 + HLA05559 + Undefined + - + + + C*06:48 + HLA05566 + Undefined + - + + + C*06:49N + HLA05576 + NotExpressed + Null + + + C*06:50 + HLA05583 + Undefined + - + + + C*06:51 + HLA05598 + Undefined + - + + + C*06:52 + HLA05619 + Undefined + - + + + C*06:53:01 + HLA05734 + Undefined + - + + + C*06:53:02 + HLA08473 + Undefined + - + + + C*06:54 + HLA05737 + Undefined + - + + + C*06:55 + HLA05884 + Undefined + - + + + C*06:56 + HLA06043 + Undefined + - + + + C*06:57 + HLA06274 + Undefined + - + + + C*06:58 + HLA06275 + Undefined + - + + + C*06:59 + HLA06407 + Undefined + - + + + C*06:60 + HLA06440 + Undefined + - + + + C*06:61 + HLA06441 + Undefined + - + + + C*06:62 + HLA06714 + Undefined + - + + + C*06:63 + HLA06732 + Undefined + - + + + C*06:64 + HLA06734 + Undefined + - + + + C*06:65 + HLA07046 + Undefined + - + + + C*06:66 + HLA07065 + Undefined + - + + + C*06:67 + HLA07069 + Undefined + - + + + C*06:68 + HLA07073 + Undefined + - + + + C*06:69 + HLA07131 + Undefined + - + + + C*06:70:01 + HLA07478 + Undefined + - + + + C*06:70:02 + HLA13241 + Undefined + - + + + C*06:71 + HLA07479 + Undefined + - + + + C*06:72 + HLA07480 + Undefined + - + + + C*06:73 + HLA07557 + Undefined + - + + + C*06:74Q + HLA07733 + Undefined + - + + + C*06:75 + HLA07740 + Undefined + - + + + C*06:76:01 + HLA07815 + Undefined + - + + + C*06:76:02 + HLA08205 + Undefined + - + + + C*06:77 + HLA07826 + Undefined + - + + + C*06:78 + HLA07827 + Undefined + - + + + C*06:79N + HLA07830 + NotExpressed + Null + + + C*06:80 + HLA07831 + Undefined + - + + + C*06:81 + HLA07833 + Undefined + - + + + C*06:82 + HLA07834 + Undefined + - + + + C*06:83 + HLA08098 + Undefined + - + + + C*06:84 + HLA08148 + Undefined + - + + + C*06:85 + HLA08149 + Undefined + - + + + C*06:86 + HLA08181 + Undefined + - + + + C*06:87 + HLA08182 + Undefined + - + + + C*06:88 + HLA08693 + Undefined + - + + + C*06:89 + HLA08695 + Undefined + - + + + C*06:90 + HLA08696 + Undefined + - + + + C*06:91 + HLA08697 + Undefined + - + + + C*06:92 + HLA08700 + Undefined + - + + + C*06:93 + HLA08701 + Undefined + - + + + C*06:94 + HLA09014 + Undefined + - + + + C*06:95 + HLA09015 + Undefined + - + + + C*06:96 + HLA09017 + Undefined + - + + + C*06:97 + HLA09179 + Undefined + - + + + C*06:98 + HLA09182 + Undefined + - + + + C*06:99 + HLA09473 + Undefined + - + + + C*06:100 + HLA09515 + Undefined + - + + + C*06:101 + HLA09599 + Undefined + - + + + C*06:102:01 + HLA09601 + Undefined + - + + + C*06:102:02 + HLA15809 + Undefined + - + + + C*06:103 + HLA09938 + Undefined + - + + + C*06:104 + HLA09967 + Undefined + - + + + C*06:105 + HLA09969 + Undefined + - + + + C*06:106:01 + HLA09971 + Undefined + - + + + C*06:106:02 + HLA09973 + Undefined + - + + + C*06:107 + HLA09978 + Undefined + - + + + C*06:108 + HLA09980 + Undefined + - + + + C*06:109 + HLA09982 + Undefined + - + + + C*06:110 + HLA09988 + Undefined + - + + + C*06:111 + HLA09990 + Undefined + - + + + C*06:112 + HLA10060 + Undefined + - + + + C*06:113 + HLA10061 + Undefined + - + + + C*06:114 + HLA10063 + Undefined + - + + + C*06:115 + HLA10075 + Undefined + - + + + C*06:116N + HLA10196 + NotExpressed + Null + + + C*06:117 + HLA10261 + Undefined + - + + + C*06:118 + HLA10426 + Undefined + - + + + C*06:119 + HLA10431 + Undefined + - + + + C*06:120 + HLA10432 + Undefined + - + + + C*06:121 + HLA10601 + Undefined + - + + + C*06:122 + HLA10603 + Undefined + - + + + C*06:123 + HLA10604 + Undefined + - + + + C*06:124 + HLA10924 + Undefined + - + + + C*06:125 + HLA11041 + Undefined + - + + + C*06:126 + HLA11045 + Undefined + - + + + C*06:127:01:01 + HLA11046 + Undefined + - + + + C*06:127:01:02 + HLA15137 + Undefined + - + + + C*06:127:02 + HLA12318 + Undefined + - + + + C*06:128N + HLA11050 + NotExpressed + Null + + + C*06:129 + HLA11438 + Undefined + - + + + C*06:130 + HLA11456 + Undefined + - + + + C*06:131 + HLA11457 + Undefined + - + + + C*06:132:01 + HLA11577 + Undefined + - + + + C*06:132:02 + HLA11580 + Undefined + - + + + C*06:133 + HLA12020 + Undefined + - + + + C*06:134N + HLA12086 + NotExpressed + Null + + + C*06:135 + HLA12087 + Undefined + - + + + C*06:136 + HLA12096 + Undefined + - + + + C*06:137 + HLA12137 + Undefined + - + + + C*06:138 + HLA12317 + Undefined + - + + + C*06:139 + HLA12320 + Undefined + - + + + C*06:140 + HLA12321 + Undefined + - + + + C*06:141 + HLA12322 + Undefined + - + + + C*06:142 + HLA12498 + Undefined + - + + + C*06:143 + HLA12499 + Undefined + - + + + C*06:144 + HLA12656 + Undefined + - + + + C*06:145 + HLA12667 + Undefined + - + + + C*06:146 + HLA12675 + Undefined + - + + + C*06:147 + HLA12694 + Undefined + - + + + C*06:148 + HLA12696 + Undefined + - + + + C*06:149 + HLA12722 + Undefined + - + + + C*06:150 + HLA13031 + Undefined + - + + + C*06:151 + HLA13032 + Undefined + - + + + C*06:152N + HLA13033 + NotExpressed + Null + + + C*06:153:01 + HLA13413 + Undefined + - + + + C*06:153:02 + HLA29997 + Undefined + - + + + C*06:154 + HLA13415 + Undefined + - + + + C*06:155:01:01 + HLA13424 + Undefined + - + + + C*06:155:01:02 + HLA15217 + Undefined + - + + + C*06:156 + HLA13516 + Undefined + - + + + C*06:157 + HLA13550 + Undefined + - + + + C*06:158 + HLA13551 + Undefined + - + + + C*06:159 + HLA13561 + Undefined + - + + + C*06:160 + HLA13638 + Undefined + - + + + C*06:161 + HLA13665 + Undefined + - + + + C*06:162 + HLA13666 + Undefined + - + + + C*06:163 + HLA13745 + Undefined + - + + + C*06:164 + HLA13746 + Undefined + - + + + C*06:165 + HLA13868 + Undefined + - + + + C*06:166 + HLA14094 + Undefined + - + + + C*06:167 + HLA14243 + Undefined + - + + + C*06:168 + HLA14244 + Undefined + - + + + C*06:169 + HLA14319 + Undefined + - + + + C*06:170 + HLA14321 + Undefined + - + + + C*06:171:01:01N + HLA14522 + NotExpressed + Null + + + C*06:171:01:02N + HLA20839 + NotExpressed + Null + + + C*06:172 + HLA14524 + Undefined + - + + + C*06:173 + HLA14530 + Undefined + - + + + C*06:174 + HLA14738 + Undefined + - + + + C*06:175N + HLA14739 + NotExpressed + Null + + + C*06:176:01 + HLA14894 + Undefined + - + + + C*06:176:02 + HLA37427 + Undefined + - + + + C*06:177 + HLA15036 + Undefined + - + + + C*06:178 + HLA15037 + Undefined + - + + + C*06:179 + HLA15038 + Undefined + - + + + C*06:180 + HLA15040 + Undefined + - + + + C*06:181 + HLA15297 + Undefined + - + + + C*06:182 + HLA15174 + Undefined + - + + + C*06:183 + HLA15176 + Undefined + - + + + C*06:184 + HLA15183 + Undefined + - + + + C*06:185 + HLA15207 + Undefined + - + + + C*06:186 + HLA15220 + Undefined + - + + + C*06:187 + HLA15221 + Undefined + - + + + C*06:188 + HLA15422 + Undefined + - + + + C*06:189 + HLA15423 + Undefined + - + + + C*06:190 + HLA15470 + Undefined + - + + + C*06:191 + HLA15648 + Undefined + - + + + C*06:192 + HLA15649 + Undefined + - + + + C*06:193 + HLA15801 + Undefined + - + + + C*06:194 + HLA15886 + Undefined + - + + + C*06:195 + HLA15977 + Undefined + - + + + C*06:196 + HLA15978 + Undefined + - + + + C*06:197 + HLA16393 + Undefined + - + + + C*06:198 + HLA16512 + Undefined + - + + + C*06:199 + HLA16621 + Undefined + - + + + C*06:200Q + HLA17007 + Undefined + - + + + C*06:201 + HLA17418 + Undefined + - + + + C*06:202 + HLA17503 + Undefined + - + + + C*06:203 + HLA17504 + Undefined + - + + + C*06:204 + HLA17505 + Undefined + - + + + C*06:205 + HLA17658 + Undefined + - + + + C*06:206 + HLA17875 + Undefined + - + + + C*06:207 + HLA17876 + Undefined + - + + + C*06:208N + HLA17877 + NotExpressed + Null + + + C*06:209:01 + HLA17878 + Undefined + - + + + C*06:209:02 + HLA31727 + Undefined + - + + + C*06:210 + HLA17879 + Undefined + - + + + C*06:211:01:01N + HLA18007 + NotExpressed + Null + + + C*06:211:01:02N + HLA23948 + NotExpressed + Null + + + C*06:212 + HLA18047 + Undefined + - + + + C*06:213 + HLA18457 + Undefined + - + + + C*06:214 + HLA18550 + Undefined + - + + + C*06:215N + HLA18584 + NotExpressed + Null + + + C*06:216 + HLA18503 + Undefined + - + + + C*06:217 + HLA18505 + Undefined + - + + + C*06:218 + HLA18514 + Undefined + - + + + C*06:219 + HLA18858 + Undefined + - + + + C*06:220N + HLA19367 + NotExpressed + Null + + + C*06:221 + HLA19188 + Undefined + - + + + C*06:222 + HLA19575 + Undefined + - + + + C*06:223 + HLA19453 + Undefined + - + + + C*06:224 + HLA19640 + Undefined + - + + + C*06:225 + HLA19896 + Undefined + - + + + C*06:226 + HLA19836 + Undefined + - + + + C*06:227 + HLA19595 + Undefined + - + + + C*06:228 + HLA19728 + Undefined + - + + + C*06:229 + HLA19885 + Undefined + - + + + C*06:230 + HLA20086 + Undefined + - + + + C*06:231 + HLA20337 + Undefined + - + + + C*06:232 + HLA20137 + Undefined + - + + + C*06:233 + HLA20186 + Undefined + - + + + C*06:234 + HLA20483 + Undefined + - + + + C*06:235 + HLA20455 + Undefined + - + + + C*06:236 + HLA20204 + Undefined + - + + + C*06:237 + HLA20218 + Undefined + - + + + C*06:238 + HLA20156 + Undefined + - + + + C*06:239 + HLA20464 + Undefined + - + + + C*06:240 + HLA20448 + Undefined + - + + + C*06:241 + HLA20449 + Undefined + - + + + C*06:242 + HLA20295 + Undefined + - + + + C*06:243 + HLA19998 + Undefined + - + + + C*06:244 + HLA20515 + Undefined + - + + + C*06:245 + HLA21059 + Undefined + - + + + C*06:246 + HLA21004 + Undefined + - + + + C*06:247 + HLA20692 + Undefined + - + + + C*06:248 + HLA20795 + Undefined + - + + + C*06:249 + HLA21094 + Undefined + - + + + C*06:250 + HLA21594 + Undefined + - + + + C*06:251 + HLA21416 + Undefined + - + + + C*06:252 + HLA22026 + Undefined + - + + + C*06:253 + HLA21980 + Undefined + - + + + C*06:254 + HLA22177 + Undefined + - + + + C*06:255 + HLA22154 + Undefined + - + + + C*06:256 + HLA22358 + Undefined + - + + + C*06:257N + HLA22514 + NotExpressed + Null + + + C*06:258 + HLA22342 + Undefined + - + + + C*06:259N + HLA22424 + NotExpressed + Null + + + C*06:260 + HLA22425 + Undefined + - + + + C*06:261 + HLA22288 + Undefined + - + + + C*06:262 + HLA22353 + Undefined + - + + + C*06:263N + HLA22698 + NotExpressed + Null + + + C*06:264 + HLA22821 + Undefined + - + + + C*06:265 + HLA22856 + Undefined + - + + + C*06:266 + HLA23547 + Undefined + - + + + C*06:267N + HLA23319 + NotExpressed + Null + + + C*06:268 + HLA23090 + Undefined + - + + + C*06:269 + HLA23740 + Undefined + - + + + C*06:270 + HLA23453 + Undefined + - + + + C*06:271 + HLA23095 + Undefined + - + + + C*06:272 + HLA23093 + Undefined + - + + + C*06:273 + HLA24123 + Undefined + - + + + C*06:274 + HLA24252 + Undefined + - + + + C*06:275 + HLA24260 + Undefined + - + + + C*06:276 + HLA23907 + Undefined + - + + + C*06:277:01:01 + HLA23901 + Undefined + - + + + C*06:277:01:02 + HLA28294 + Undefined + - + + + C*06:278 + HLA24081 + Undefined + - + + + C*06:279 + HLA23979 + Undefined + - + + + C*06:280 + HLA24199 + Undefined + - + + + C*06:281N + HLA24000 + NotExpressed + Null + + + C*06:282 + HLA24057 + Undefined + - + + + C*06:283 + HLA24339 + Undefined + - + + + C*06:284 + HLA24954 + Undefined + - + + + C*06:285Q + HLA24628 + Undefined + - + + + C*06:286 + HLA24575 + Undefined + - + + + C*06:287 + HLA25567 + Undefined + - + + + C*06:288 + HLA26052 + Undefined + - + + + C*06:289 + HLA25878 + Undefined + - + + + C*06:290 + HLA25634 + Undefined + - + + + C*06:291 + HLA26150 + Undefined + - + + + C*06:292 + HLA26109 + Undefined + - + + + C*06:293 + HLA27166 + Undefined + - + + + C*06:294 + HLA27179 + Undefined + - + + + C*06:295 + HLA27695 + Undefined + - + + + C*06:296 + HLA27699 + Undefined + - + + + C*06:297 + HLA27545 + Undefined + - + + + C*06:298 + HLA27812 + Undefined + - + + + C*06:299 + HLA27816 + Undefined + - + + + C*06:300 + HLA27862 + Undefined + - + + + C*06:301N + HLA27876 + NotExpressed + Null + + + C*06:302 + HLA27921 + Undefined + - + + + C*06:303 + HLA28133 + Undefined + - + + + C*06:304 + HLA28144 + Undefined + - + + + C*06:305 + HLA28163 + Undefined + - + + + C*06:306 + HLA28093 + Undefined + - + + + C*06:307 + HLA28102 + Undefined + - + + + C*06:308 + HLA28282 + Undefined + - + + + C*06:309N + HLA28501 + NotExpressed + Null + + + C*06:310 + HLA28682 + Undefined + - + + + C*06:311 + HLA28772 + Undefined + - + + + C*06:312 + HLA29198 + Undefined + - + + + C*06:313 + HLA29240 + Undefined + - + + + C*06:314 + HLA29270 + Undefined + - + + + C*06:315 + HLA29455 + Undefined + - + + + C*06:316N + HLA29358 + NotExpressed + Null + + + C*06:317 + HLA29703 + Undefined + - + + + C*06:318 + HLA29809 + Undefined + - + + + C*06:319 + HLA29975 + Undefined + - + + + C*06:320 + HLA29990 + Undefined + - + + + C*06:321 + HLA29993 + Undefined + - + + + C*06:322:01 + HLA29971 + Undefined + - + + + C*06:322:02 + HLA37214 + Undefined + - + + + C*06:323N + HLA30556 + NotExpressed + Null + + + C*06:324 + HLA30773 + Undefined + - + + + C*06:325 + HLA30507 + Undefined + - + + + C*06:326Q + HLA30851 + Undefined + - + + + C*06:327 + HLA30946 + Undefined + - + + + C*06:328 + HLA31055 + Undefined + - + + + C*06:329:01:01 + HLA31064 + Undefined + - + + + C*06:329:01:02 + HLA31786 + Undefined + - + + + C*06:330 + HLA31060 + Undefined + - + + + C*06:331 + HLA31121 + Undefined + - + + + C*06:332 + HLA31791 + Undefined + - + + + C*06:333 + HLA31645 + Undefined + - + + + C*06:334 + HLA31538 + Undefined + - + + + C*06:335 + HLA31731 + Undefined + - + + + C*06:336Q + HLA33054 + Undefined + - + + + C*06:337 + HLA33080 + Undefined + - + + + C*06:338N + HLA32644 + NotExpressed + Null + + + C*06:339 + HLA33582 + Undefined + - + + + C*06:340 + HLA33639 + Undefined + - + + + C*06:341 + HLA33632 + Undefined + - + + + C*06:342 + HLA33657 + Undefined + - + + + C*06:343 + HLA33502 + Undefined + - + + + C*06:344 + HLA33539 + Undefined + - + + + C*06:345 + HLA33661 + Undefined + - + + + C*06:346 + HLA33581 + 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Cw7 + Cw7 + + + C*07:04:04 + HLA05352 + Cw7 + Cw7 + + + C*07:04:05 + HLA06444 + Cw7 + Cw7 + + + C*07:04:06 + HLA06824 + Cw7 + Cw7 + + + C*07:04:07 + HLA07272 + Cw7 + Cw7 + + + C*07:04:08 + HLA08184 + Cw7 + Cw7 + + + C*07:04:09 + HLA10425 + Cw7 + Cw7 + + + C*07:04:10 + HLA12713 + Cw7 + Cw7 + + + C*07:04:11 + HLA15120 + Cw7 + Cw7 + + + C*07:04:12 + HLA18502 + Cw7 + Cw7 + + + C*07:04:13 + HLA18746 + Cw7 + Cw7 + + + C*07:04:14 + HLA19191 + Cw7 + Cw7 + + + C*07:04:15 + HLA20235 + Cw7 + Cw7 + + + C*07:04:16 + HLA20038 + Cw7 + Cw7 + + + C*07:04:17 + HLA20899 + Cw7 + Cw7 + + + C*07:04:18 + HLA21410 + Cw7 + Cw7 + + + C*07:04:19 + HLA23682 + Cw7 + Cw7 + + + C*07:04:20 + HLA26997 + Cw7 + Cw7 + + + C*07:04:21 + HLA27689 + Cw7 + Cw7 + + + C*07:04:22 + HLA27814 + Cw7 + Cw7 + + + C*07:04:23 + HLA28120 + Cw7 + Cw7 + + + C*07:04:24 + HLA28297 + Cw7 + Cw7 + + + C*07:04:25 + HLA28899 + Cw7 + Cw7 + + + C*07:04:26 + HLA31232 + Cw7 + Cw7 + + + C*07:04:27 + HLA33288 + Cw7 + Cw7 + + + C*07:04:28 + HLA35114 + Cw7 + Cw7 + + + C*07:04:29 + HLA38071 + Cw7 + Cw7 + + + C*07:05 + HLA00437 + Cw7 + Cw7 + + + C*07:06:01:01 + HLA00438 + Cw7 + Cw7 + + + C*07:06:01:02 + HLA18014 + Cw7 + Cw7 + + + C*07:06:01:03 + HLA24741 + Cw7 + Cw7 + + + C*07:06:01:04 + HLA25289 + Cw7 + Cw7 + + + C*07:06:01:05Q + HLA25476 + Undefined + - + + + C*07:06:01:06 + HLA25842 + Cw7 + Cw7 + + + C*07:06:01:07 + HLA25573 + Cw7 + Cw7 + + + C*07:06:01:08 + HLA26106 + Cw7 + Cw7 + + + C*07:06:01:09 + HLA33414 + Cw7 + Cw7 + + + C*07:06:01:10 + HLA33187 + Cw7 + Cw7 + + + C*07:06:01:11 + HLA33371 + Cw7 + Cw7 + + + C*07:06:01:12 + HLA33823 + Cw7 + Cw7 + + + C*07:06:02 + HLA19099 + Cw7 + Cw7 + + + C*07:06:03 + HLA23806 + Cw7 + Cw7 + + + C*07:06:04 + HLA27817 + Cw7 + Cw7 + + + C*07:06:05 + HLA32743 + Cw7 + Cw7 + + + C*07:06:06 + HLA34193 + Cw7 + Cw7 + + + C*07:07 + HLA00439 + Cw7 + - + + + C*07:08 + HLA00440 + Cw7 + - + + + C*07:09 + HLA00441 + Cw7 + - + + + C*07:10 + HLA00442 + Cw7 + - + + + C*07:11 + HLA00443 + Cw7 + - + + + C*07:12 + HLA00444 + Cw7 + Cw7 + + + C*07:13:01:01 + HLA01079 + Cw7 + - + + + C*07:13:01:02 + HLA26741 + Cw7 + - + + + C*07:14 + HLA01080 + Cw7 + Cw7 + + + C*07:15 + HLA01408 + Cw7 + - + + + C*07:16 + HLA01588 + Cw7 + Cw7 + + + C*07:17:01:01 + HLA01662 + Cw7 + - + + + C*07:17:01:02 + HLA25447 + Cw7 + - + + + C*07:17:02 + HLA08720 + Cw7 + - + + + C*07:17:03 + HLA15902 + Cw7 + - + + + C*07:17:04 + HLA17883 + Cw7 + - + + + C*07:18:01:01 + HLA01672 + Cw7 + - + + + C*07:18:01:02 + HLA19691 + Cw7 + - + + + C*07:18:01:03 + HLA21288 + Cw7 + - + + + C*07:18:01:04 + HLA28414 + Cw7 + - + + + C*07:18:01:05 + HLA29157 + Cw7 + - + + + C*07:18:01:06 + HLA30737 + Cw7 + - + + + C*07:18:01:07 + HLA31984 + Cw7 + - + + + C*07:18:01:08 + HLA33166 + Cw7 + - + + + C*07:18:01:09 + HLA32929 + Cw7 + - + + + C*07:18:01:10 + HLA32909 + Cw7 + - + + + C*07:18:01:11 + HLA33416 + Cw7 + - + + + C*07:18:02 + HLA19444 + Cw7 + - + + + C*07:18:03 + HLA20621 + Cw7 + - + + + C*07:18:04 + HLA01865 + Cw7 + - + + + C*07:18:05 + HLA25438 + Cw7 + - + + + C*07:18:06 + HLA28263 + Cw7 + - + + + C*07:18:07 + HLA29190 + Cw7 + - + + + C*07:18:08:01 + HLA29258 + Cw7 + - + + + C*07:18:08:02 + HLA29704 + Cw7 + - + + + C*07:18:09 + HLA29951 + Cw7 + - + + + C*07:18:10 + HLA35349 + Cw7 + - + + + C*07:18:11 + HLA37710 + Cw7 + - + + + C*07:19 + HLA01720 + Cw7 + - + + + C*07:20:01 + HLA01729 + Cw7 + - + + + C*07:20:02 + HLA22310 + Cw7 + - + + + C*07:21 + HLA01833 + Cw7 + - + + + C*07:22 + HLA01844 + Cw7 + - + + + C*07:23 + HLA01863 + Cw7 + - + + + C*07:24 + HLA01864 + Cw7 + - + + + C*07:25 + HLA01877 + Cw7 + - + + + C*07:26:01:01 + HLA01889 + Cw7 + - + + + C*07:26:01:02 + HLA24839 + Cw7 + - + + + C*07:26:02 + HLA14534 + Cw7 + - + + + C*07:26:03 + HLA17891 + Cw7 + - + + + C*07:27:01 + HLA01908 + Cw7 + - + + + C*07:27:02 + HLA03107 + Cw7 + - + + + C*07:28 + HLA01961 + Cw7 + - + + + C*07:29:01:01 + HLA02010 + Cw7 + - + + + C*07:29:01:02 + HLA25011 + Cw7 + - + + + C*07:29:02 + HLA14023 + Cw7 + - + + + C*07:30 + HLA02139 + Cw7 + Cw7 + + + C*07:31:01 + HLA02205 + Cw7 + - + + + C*07:31:02 + HLA08529 + Cw7 + - + + + C*07:32N + HLA02354 + NotExpressed + Null + + + C*07:33N + HLA02380 + NotExpressed + Null + + + C*07:35 + HLA02425 + Cw7 + - + + + C*07:36 + HLA02448 + Cw7 + Cw7 + + + C*07:37:01:02 + HLA28358 + Cw7 + Cw7 + + + C*07:37 + HLA02459 + Cw7 + Cw7 + + + C*07:38:01 + HLA02475 + Cw7 + Cw7 + + + C*07:38:02 + HLA07485 + Cw7 + Cw7 + + + C*07:39 + HLA02564 + Cw7 + - + + + C*07:40 + HLA02598 + Cw7 + Cw7 + + + C*07:41 + HLA02614 + Undefined + - + + + C*07:42 + HLA02680 + Cw7 + - + + + C*07:43:01 + HLA02697 + Cw7 + - + + + C*07:43:02 + HLA15472 + Cw7 + - + + + C*07:44 + HLA02709 + Cw7 + Cw7 + + + C*07:45 + HLA02730 + Cw7 + Cw7 + + + C*07:46 + HLA02789 + Cw7 + - + + + C*07:47:01 + HLA02834 + Cw7 + - + + + C*07:47:02 + HLA33492 + Cw7 + - + + + C*07:47:03 + HLA37752 + Cw7 + - + + + C*07:48 + HLA02835 + Cw7 + - + + + C*07:49 + HLA02943 + Cw7 + Cw7 + + + C*07:50 + HLA03004 + Undefined + - + + + C*07:51 + HLA03013 + Undefined + - + + + C*07:52 + HLA03135 + Undefined + - + + + C*07:53 + HLA03139 + Undefined + - + + + C*07:54 + HLA03239 + Undefined + - + + + C*07:55N + HLA03298 + NotExpressed + Null + + + C*07:56:01 + HLA03310 + Undefined + - + + + C*07:56:02 + HLA03753 + Undefined + - + + + C*07:57 + HLA03365 + Undefined + - + + + C*07:58 + HLA03414 + Undefined + - + + + C*07:59 + HLA03419 + Undefined + - + + + C*07:60 + HLA03436 + Undefined + - + + + C*07:61N + HLA03439 + NotExpressed + Null + + + C*07:62 + HLA03444 + Undefined + - + + + C*07:63 + HLA03477 + Undefined + - + + + C*07:64 + HLA03515 + Undefined + - + + + C*07:65 + HLA03546 + Undefined + - + + + C*07:66 + HLA03631 + Undefined + - + + + C*07:67 + HLA03623 + Undefined + - + + + C*07:68 + HLA03698 + Undefined + - + + + C*07:69 + HLA03700 + Undefined + - + + + C*07:70 + HLA03701 + Undefined + - + + + C*07:71 + HLA03702 + Undefined + - + + + C*07:72 + HLA03703 + Undefined + - + + + C*07:73:01 + HLA03819 + Undefined + - + + + C*07:73:02 + HLA18395 + Undefined + - + + + C*07:74 + HLA03977 + Undefined + - + + + C*07:75 + HLA04021 + Undefined + - + + + C*07:76:01 + HLA04130 + Undefined + - + + + C*07:76:02 + HLA11047 + Undefined + - + + + C*07:77 + HLA04318 + Undefined + - + + + C*07:78:01 + HLA04322 + Undefined + - + + + C*07:78:02 + HLA13517 + Undefined + - + + + C*07:79 + HLA04323 + Undefined + - + + + C*07:80 + HLA04324 + Undefined + - + + + C*07:81 + HLA04328 + Undefined + - + + + C*07:82 + HLA04329 + Undefined + - + + + C*07:83 + HLA04330 + Undefined + - + + + C*07:84 + HLA04331 + Undefined + - + + + C*07:85 + HLA04335 + Undefined + - + + + C*07:86 + HLA04338 + Undefined + - + + + C*07:87 + HLA04339 + Undefined + - + + + C*07:88 + HLA04342 + Undefined + - + + + C*07:89 + HLA04343 + Undefined + - + + + C*07:90 + HLA04347 + Undefined + - + + + C*07:91 + HLA04348 + Undefined + - + + + C*07:92 + HLA04396 + Undefined + - + + + C*07:93:01 + HLA04399 + Undefined + - + + + C*07:93:02 + HLA24905 + Undefined + - + + + C*07:94 + HLA04588 + Undefined + - + + + C*07:95 + HLA04594 + Undefined + - + + + C*07:96:01 + HLA04597 + Undefined + - + + + C*07:96:02 + HLA08762 + Undefined + - + + + C*07:97 + HLA04601 + Undefined + - + + + C*07:98N + HLA04607 + NotExpressed + Null + + + C*07:99 + HLA04609 + Undefined + - + + + C*07:100 + HLA04974 + Undefined + - + + + C*07:101 + HLA04982 + Undefined + - + + + C*07:102 + HLA04983 + Undefined + - + + + C*07:103 + HLA04995 + Undefined + - + + + C*07:104N + HLA04996 + NotExpressed + Null + + + C*07:105 + HLA05012 + Undefined + - + + + C*07:106 + HLA05013 + Undefined + - + + + C*07:107 + HLA05014 + Undefined + - + + + C*07:108:01 + HLA05015 + Undefined + - + + + C*07:108:02 + HLA10902 + Undefined + - + + + C*07:109:01 + HLA05016 + Undefined + - + + + C*07:109:02 + HLA17608 + Undefined + - + + + C*07:110 + HLA05017 + Undefined + - + + + C*07:111 + HLA05022 + Undefined + - + + + C*07:112 + HLA05023 + Undefined + - + + + C*07:113 + HLA05024 + Undefined + - + + + C*07:114 + HLA05025 + Undefined + - + + + C*07:115 + HLA05026 + Undefined + - + + + C*07:116 + HLA05027 + Undefined + - + + + C*07:117 + HLA05028 + Undefined + - + + + C*07:118 + HLA05029 + Undefined + - + + + C*07:119 + HLA05030 + Undefined + - + + + C*07:120 + HLA05031 + Undefined + - + + + C*07:121Q + HLA05032 + Undefined + - + + + C*07:122 + HLA05033 + Undefined + - + + + C*07:123:01 + HLA05034 + Undefined + - + + + C*07:123:02 + HLA29981 + Undefined + - + + + C*07:124 + HLA05035 + Undefined + - + + + C*07:125:01 + HLA05036 + Undefined + - + + + C*07:125:02 + HLA29948 + Undefined + - + + + C*07:126 + HLA05064 + Undefined + - + + + C*07:127:01 + HLA05065 + Undefined + - + + + C*07:127:02 + HLA20307 + Undefined + - + + + C*07:128 + HLA05066 + Undefined + - + + + C*07:129 + HLA05067 + Undefined + - + + + C*07:130 + HLA05068 + Undefined + - + + + C*07:131:01 + HLA05069 + Undefined + - + + + C*07:131:02 + HLA12350 + Undefined + - + + + C*07:132 + HLA05070 + Undefined + - + + + C*07:133:01 + HLA05071 + Undefined + - + + + C*07:133:02 + HLA21134 + Undefined + - + + + C*07:134 + HLA05072 + Undefined + - + + + C*07:135 + HLA05073 + Undefined + - + + + C*07:136 + HLA05074 + Undefined + - + + + C*07:137:01 + HLA05075 + Undefined + - + + + C*07:137:02 + HLA05855 + Undefined + - + + + C*07:138 + HLA05076 + Undefined + - + + + C*07:139 + HLA05077 + Undefined + - + + + C*07:140:01 + HLA05089 + Undefined + - + + + C*07:140:02 + HLA27807 + Undefined + - + + + C*07:141:01 + HLA05090 + Undefined + - + + + C*07:141:02 + HLA07835 + Undefined + - + + + C*07:141:03 + HLA28278 + Undefined + - + + + C*07:142 + HLA05079 + Undefined + - + + + C*07:143 + HLA05080 + Undefined + - + + + C*07:144 + HLA05081 + Undefined + - + + + C*07:145 + HLA05082 + Undefined + - + + + C*07:146 + HLA05083 + Undefined + - + + + C*07:147 + HLA05138 + Undefined + - + + + C*07:148 + HLA05221 + Undefined + - + + + C*07:149 + HLA05419 + Undefined + - + + + C*07:150Q + HLA05544 + Undefined + - + + + C*07:151 + HLA05554 + Undefined + - + + + C*07:152N + HLA05612 + NotExpressed + Null + + + C*07:153:01 + HLA05764 + Undefined + - + + + C*07:153:02 + HLA37599 + Undefined + - + + + C*07:154 + HLA05780 + Undefined + - + + + C*07:155 + HLA05820 + Undefined + - + + + C*07:156 + HLA05885 + Undefined + - + + + C*07:157 + HLA05886 + Undefined + - + + + C*07:158 + HLA05887 + Undefined + - + + + C*07:159 + HLA05888 + Undefined + - + + + C*07:160 + HLA05889 + Undefined + - + + + C*07:161 + HLA05920 + Undefined + - + + + C*07:162 + HLA05996 + Undefined + - + + + C*07:163 + HLA06048 + Undefined + - + + + C*07:164N + HLA06069 + NotExpressed + Null + + + C*07:165 + HLA06070 + Undefined + - + + + C*07:166 + HLA06071 + Undefined + - + + + C*07:167 + HLA06127 + Undefined + - + + + C*07:168 + HLA06170 + Undefined + - + + + C*07:169 + HLA06171 + Undefined + - + + + C*07:170 + HLA06277 + Undefined + - + + + C*07:171 + HLA06306 + Undefined + - + + + C*07:172:01 + HLA06387 + Undefined + - + + + C*07:172:02 + HLA10614 + Undefined + - + + + C*07:173 + HLA06389 + Undefined + - + + + C*07:174 + HLA06391 + Undefined + - + + + C*07:175 + HLA06392 + Undefined + - + + + C*07:176 + HLA06408 + Undefined + - + + + C*07:177 + HLA06409 + Undefined + - + + + C*07:178 + HLA06410 + Undefined + - + + + C*07:179 + HLA06423 + Undefined + - + + + C*07:180 + HLA06425 + Undefined + - + + + C*07:181 + HLA06429 + Undefined + - + + + C*07:182 + HLA06430 + Undefined + - + + + C*07:183 + HLA06437 + Undefined + - + + + C*07:184 + HLA06449 + Undefined + - + + + C*07:185 + HLA06525 + Undefined + - + + + C*07:186 + HLA06655 + Undefined + - + + + C*07:187 + HLA06662 + Undefined + - + + + C*07:188 + HLA06705 + Undefined + - + + + C*07:189 + HLA06706 + Undefined + - + + + C*07:190 + HLA06716 + Undefined + - + + + C*07:191N + HLA06717 + NotExpressed + Null + + + C*07:192 + HLA06719 + Undefined + - + + + C*07:193 + HLA06733 + Undefined + - + + + C*07:194 + HLA06735 + Undefined + - + + + C*07:195 + HLA06828 + Undefined + - + + + C*07:196 + HLA06896 + Undefined + - + + + C*07:197 + HLA06902 + Undefined + - + + + C*07:198N + HLA07051 + NotExpressed + Null + + + C*07:199:01 + HLA07057 + Undefined + - + + + C*07:199:02 + HLA08183 + Undefined + - + + + C*07:200 + HLA07058 + Undefined + - + + + C*07:201 + HLA07059 + Undefined + - + + + C*07:202 + HLA07070 + Undefined + - + + + C*07:203 + HLA07071 + Undefined + - + + + C*07:204:01 + HLA07072 + Undefined + - + + + C*07:204:02 + HLA15300 + Undefined + - + + + C*07:205 + HLA07078 + Undefined + - + + + C*07:206 + HLA07079 + Undefined + - + + + C*07:207 + HLA07081 + Undefined + - + + + C*07:208 + HLA07320 + Undefined + - + + + C*07:209 + HLA07130 + Undefined + - + + + C*07:210 + HLA07132 + Undefined + - + + + C*07:211 + HLA07133 + Undefined + - + + + C*07:212 + HLA07182 + Undefined + - + + + C*07:213 + HLA07215 + Undefined + - + + + C*07:214 + HLA07217 + Undefined + - + + + C*07:215 + HLA07218 + Undefined + - + + + C*07:216 + HLA07219 + Undefined + - + + + C*07:217 + HLA07220 + Undefined + - + + + C*07:218 + HLA07221 + Undefined + - + + + C*07:219 + HLA07316 + Undefined + - + + + C*07:220 + HLA07373 + Undefined + - + + + C*07:221 + HLA07474 + Undefined + - + + + C*07:222 + HLA07477 + Undefined + - + + + C*07:223 + HLA07481 + Undefined + - + + + C*07:224 + HLA07482 + Undefined + - + + + C*07:225 + HLA07483 + Undefined + - + + + C*07:226Q + HLA07484 + Undefined + - + + + C*07:227N + HLA07486 + NotExpressed + Null + + + C*07:228 + HLA07822 + Undefined + - + + + C*07:229 + HLA07734 + Undefined + - + + + C*07:230 + HLA07735 + Undefined + - + + + C*07:231 + HLA07736 + Undefined + - + + + C*07:232 + HLA07737 + Undefined + - + + + C*07:233 + HLA07738 + Undefined + - + + + C*07:234 + HLA07739 + Undefined + - + + + C*07:235Q + HLA07756 + Undefined + - + + + C*07:236 + HLA07829 + Undefined + - + + + C*07:237 + HLA07836 + Undefined + - + + + C*07:238 + HLA07837 + Undefined + - + + + C*07:239 + HLA07838 + Undefined + - + + + C*07:240 + HLA07839 + Undefined + - + + + C*07:241 + HLA07840 + Undefined + - + + + C*07:242 + HLA07842 + Undefined + - + + + C*07:243 + HLA07843 + Undefined + - + + + C*07:244 + HLA07930 + Undefined + - + + + C*07:245 + HLA08126 + Undefined + - + + + C*07:246:01 + HLA08147 + Undefined + - + + + C*07:246:02 + HLA15315 + Undefined + - + + + C*07:247 + HLA08150 + Undefined + - + + + C*07:248 + HLA08151 + Undefined + - + + + C*07:249 + HLA08152 + Undefined + - + + + C*07:250 + HLA08153 + Undefined + - + + + C*07:251 + HLA08179 + Undefined + - + + + C*07:252 + HLA08180 + Undefined + - + + + C*07:253 + HLA08185 + Undefined + - + + + C*07:254 + HLA08186 + Undefined + - + + + C*07:255 + HLA08187 + Undefined + - + + + C*07:256 + HLA08188 + Undefined + - + + + C*07:257:01 + HLA08189 + Undefined + - + + + C*07:257:02 + HLA12669 + Undefined + - + + + C*07:257:03 + HLA13039 + Undefined + - + + + C*07:257:04 + HLA14324 + Undefined + - + + + C*07:258 + HLA08190 + Undefined + - + + + C*07:259 + HLA08191 + Undefined + - + + + C*07:260:01 + HLA08192 + Undefined + - + + + C*07:260:02 + HLA15043 + Undefined + - + + + C*07:261 + HLA08193 + Undefined + - + + + C*07:262 + HLA08195 + Undefined + - + + + C*07:263 + HLA08197 + Undefined + - + + + C*07:264N + HLA08402 + NotExpressed + Null + + + C*07:265 + HLA08418 + Undefined + - + + + C*07:266 + HLA08474 + Undefined + - + + + C*07:267 + HLA08478 + Undefined + - + + + C*07:268 + HLA08526 + Undefined + - + + + C*07:269 + HLA08527 + Undefined + - + + + C*07:270 + HLA08528 + Undefined + - + + + C*07:271 + HLA08688 + Undefined + - + + + C*07:272 + HLA08689 + Undefined + - + + + C*07:273 + HLA08691 + Undefined + - + + + C*07:274 + HLA08692 + Undefined + - + + + C*07:275 + HLA08703 + Undefined + - + + + C*07:276 + HLA08704 + Undefined + - + + + C*07:277 + HLA08705 + Undefined + - + + + C*07:278 + HLA08706 + Undefined + - + + + C*07:279 + HLA08707 + Undefined + - + + + C*07:280:01 + HLA08708 + Undefined + - + + + C*07:280:02 + HLA30368 + Undefined + - + + + C*07:281 + HLA08710 + Undefined + - + + + C*07:282 + HLA08712 + Undefined + - + + + C*07:283 + HLA08714 + Undefined + - + + + C*07:284 + HLA08715 + Undefined + - + + + C*07:285 + HLA08716 + Undefined + - + + + C*07:286 + HLA08717 + Undefined + - + + + C*07:287:01:01 + HLA08718 + Undefined + - + + + C*07:287:01:02 + HLA33405 + Undefined + - + + + C*07:288 + HLA08719 + Undefined + - + + + C*07:289 + HLA08723 + Undefined + - + + + C*07:290 + HLA08724 + Undefined + - + + + C*07:291 + HLA08725 + Undefined + - + + + C*07:292 + HLA08726 + Undefined + - + + + C*07:293 + HLA08833 + Undefined + - + + + C*07:294 + HLA08897 + Undefined + - + + + C*07:296 + HLA09013 + Undefined + - + + + C*07:297 + HLA09018 + Undefined + - + + + C*07:298 + HLA09019 + Undefined + - + + + C*07:299 + HLA09021 + Undefined + - + + + C*07:300 + HLA09136 + Undefined + - + + + C*07:301 + HLA09178 + Undefined + - + + + C*07:302 + HLA09183 + Undefined + - + + + C*07:303 + HLA09184 + Undefined + - + + + C*07:304 + HLA09185 + Undefined + - + + + C*07:305 + HLA09187 + Undefined + - + + + C*07:306 + HLA09188 + Undefined + - + + + C*07:307 + HLA09451 + Undefined + - + + + C*07:308 + HLA09511 + Undefined + - + + + C*07:309 + HLA09598 + Undefined + - + + + C*07:310 + HLA09602 + Undefined + - + + + C*07:311 + HLA09603 + Undefined + - + + + C*07:312 + HLA09605 + Undefined + - + + + C*07:313 + HLA09606 + Undefined + - + + + C*07:314:01 + HLA09689 + Undefined + - + + + C*07:314:02 + HLA13259 + Undefined + - + + + C*07:314:03 + HLA15888 + Undefined + - + + + C*07:315 + HLA09831 + Undefined + - + + + C*07:316 + HLA09903 + Undefined + - + + + C*07:317 + HLA09906 + Undefined + - + + + C*07:318 + HLA09995 + Undefined + - + + + C*07:319 + HLA09997 + Undefined + - + + + C*07:320 + HLA10000 + Undefined + - + + + C*07:321 + HLA10001 + Undefined + - + + + C*07:322 + HLA10014 + Undefined + - + + + C*07:323 + HLA10002 + Undefined + - + + + C*07:324 + HLA10004 + Undefined + - + + + C*07:325 + HLA10053 + Undefined + - + + + C*07:326 + HLA10054 + Undefined + - + + + C*07:327 + HLA10055 + Undefined + - + + + C*07:328 + HLA10058 + Undefined + - + + + C*07:329N + HLA10064 + NotExpressed + Null + + + C*07:330:01 + HLA10067 + Undefined + - + + + C*07:330:02 + HLA15194 + Undefined + - + + + C*07:331 + HLA10068 + Undefined + - + + + C*07:332 + HLA10070 + Undefined + - + + + C*07:333 + HLA10071 + Undefined + - + + + C*07:334 + HLA10072 + Undefined + - + + + C*07:335 + HLA10073 + Undefined + - + + + C*07:336 + HLA10074 + Undefined + - + + + C*07:337 + HLA10114 + Undefined + - + + + C*07:338 + HLA10424 + Undefined + - + + + C*07:339 + HLA10427 + Undefined + - + + + C*07:340 + HLA10430 + Undefined + - + + + C*07:341:01 + HLA10564 + Undefined + - + + + C*07:341:02 + HLA14699 + Undefined + - + + + C*07:342:01 + HLA10565 + Undefined + - + + + C*07:342:02 + HLA28791 + Undefined + - + + + C*07:343:01:01 + HLA10607 + Undefined + - + + + C*07:343:01:02 + HLA19613 + Undefined + - + + + C*07:344 + HLA10608 + Undefined + - + + + C*07:345 + HLA10609 + Undefined + - + + + C*07:346 + HLA10610 + Undefined + - + + + C*07:347N + HLA10611 + NotExpressed + Null + + + C*07:348 + HLA10613 + Undefined + - + + + C*07:349 + HLA10872 + Undefined + - + + + C*07:350N + HLA10873 + NotExpressed + Null + + + C*07:351 + HLA10922 + Undefined + - + + + C*07:352 + HLA10930 + Undefined + - + + + C*07:353 + HLA10931 + Undefined + - + + + C*07:354 + HLA10925 + Undefined + - + + + C*07:355 + HLA11042 + Undefined + - + + + C*07:356 + HLA11044 + Undefined + - + + + C*07:357 + HLA11048 + Undefined + - + + + C*07:358 + HLA11049 + Undefined + - + + + C*07:359 + HLA11071 + Undefined + - + + + C*07:360 + HLA11553 + Undefined + - + + + C*07:361 + HLA11252 + Undefined + - + + + C*07:362 + HLA11253 + Undefined + - + + + C*07:363 + HLA11254 + Undefined + - + + + C*07:364 + HLA11335 + Undefined + - + + + C*07:365 + HLA11336 + Undefined + - + + + C*07:366 + HLA11337 + Undefined + - + + + C*07:367 + HLA11338 + Undefined + - + + + C*07:368:01 + HLA11347 + Undefined + - + + + C*07:368:02 + HLA15316 + Undefined + - + + + C*07:369 + HLA11556 + Undefined + - + + + C*07:370 + HLA11458 + Undefined + - + + + C*07:371 + HLA11459 + Undefined + - + + + C*07:372 + HLA11461 + Undefined + - + + + C*07:373 + HLA11462 + Undefined + - + + + C*07:374 + HLA11463 + Undefined + - + + + C*07:375 + HLA11773 + Undefined + - + + + C*07:376 + HLA11852 + Undefined + - + + + C*07:377 + HLA11854 + Undefined + - + + + C*07:378 + HLA11856 + Undefined + - + + + C*07:379 + HLA12019 + Undefined + - + + + C*07:380 + HLA11977 + Undefined + - + + + C*07:381 + HLA12040 + Undefined + - + + + C*07:382 + HLA12041 + Undefined + - + + + C*07:383 + HLA12081 + Undefined + - + + + C*07:384 + HLA12083 + Undefined + - + + + C*07:385 + HLA12094 + Undefined + - + + + C*07:386 + HLA12097 + Undefined + - + + + C*07:387 + HLA12139 + Undefined + - + + + C*07:388 + HLA12140 + Undefined + - + + + C*07:389 + HLA12141 + Undefined + - + + + C*07:390 + HLA12142 + Undefined + - + + + C*07:391 + HLA12145 + Undefined + - + + + C*07:392 + HLA12155 + Undefined + - + + + C*07:393N + HLA12185 + NotExpressed + Null + + + C*07:394 + HLA12323 + Undefined + - + + + C*07:395 + HLA12324 + Undefined + - + + + C*07:396 + HLA12325 + Undefined + - + + + C*07:397 + HLA12326 + Undefined + - + + + C*07:398 + HLA12327 + Undefined + - + + + C*07:399 + HLA12328 + Undefined + - + + + C*07:400 + HLA12329 + Undefined + - + + + C*07:401 + HLA12330 + Undefined + - + + + C*07:402:01 + HLA12712 + Undefined + - + + + C*07:402:02 + HLA37582 + Undefined + - + + + C*07:403 + HLA12724 + Undefined + - + + + C*07:404 + HLA12739 + Undefined + - + + + C*07:405:01 + HLA12740 + Undefined + - + + + C*07:405:02 + HLA29173 + Undefined + - + + + C*07:406 + HLA12767 + Undefined + - + + + C*07:407 + HLA12768 + Undefined + - + + + C*07:408 + HLA12769 + Undefined + - + + + C*07:409 + HLA12770 + Undefined + - + + + C*07:410 + HLA13035 + Undefined + - + + + C*07:411 + HLA13036 + Undefined + - + + + C*07:412 + HLA13037 + Undefined + - + + + C*07:413 + HLA13029 + Undefined + - + + + C*07:414 + HLA13034 + Undefined + - + + + C*07:415 + HLA13041 + Undefined + - + + + C*07:416 + HLA13042 + Undefined + - + + + C*07:417 + HLA13094 + Undefined + - + + + C*07:418 + HLA13095 + Undefined + - + + + C*07:419 + HLA13202 + Undefined + - + + + C*07:420 + HLA13406 + Undefined + - + + + C*07:421 + HLA13410 + Undefined + - + + + C*07:422 + HLA13423 + Undefined + - + + + C*07:423 + HLA13393 + Undefined + - + + + C*07:424 + HLA13518 + Undefined + - + + + C*07:425 + HLA13530 + Undefined + - + + + C*07:426 + HLA13532 + Undefined + - + + + C*07:427 + HLA13549 + Undefined + - + + + C*07:428 + HLA13552 + Undefined + - + + + C*07:429 + HLA13553 + Undefined + - + + + C*07:430 + HLA13554 + Undefined + - + + + C*07:431 + HLA13555 + Undefined + - + + + C*07:432Q + HLA13556 + Undefined + - + + + C*07:433 + HLA13557 + Undefined + - + + + C*07:434 + HLA13558 + Undefined + - + + + C*07:435 + HLA13559 + Undefined + - + + + C*07:436 + HLA13560 + Undefined + - + + + C*07:437N + HLA13498 + NotExpressed + Null + + + C*07:438 + HLA13664 + Undefined + - + + + C*07:439 + HLA13667 + Undefined + - + + + C*07:440 + HLA13668 + Undefined + - + + + C*07:441:01 + HLA13744 + Undefined + - + + + C*07:441:02 + HLA16620 + Undefined + - + + + C*07:442 + HLA13747 + Undefined + - + + + C*07:443 + HLA13748 + Undefined + - + + + C*07:444 + HLA13749 + Undefined + - + + + C*07:445 + HLA13630 + Undefined + - + + + C*07:446 + HLA13636 + Undefined + - + + + C*07:447 + HLA13801 + Undefined + - + + + C*07:448 + HLA13863 + Undefined + - + + + C*07:449 + HLA13866 + Undefined + - + + + C*07:450:01 + HLA13869 + Undefined + - + + + C*07:450:02 + HLA35330 + Undefined + - + + + C*07:451N + HLA13870 + NotExpressed + Null + + + C*07:452N + HLA13871 + NotExpressed + Null + + + C*07:453 + HLA13758 + Undefined + - + + + C*07:454:01 + HLA14021 + Undefined + - + + + C*07:454:02 + HLA15298 + Undefined + - + + + C*07:455 + HLA14022 + Undefined + - + + + C*07:456 + HLA14024 + Undefined + - + + + C*07:457 + HLA14025 + Undefined + - + + + C*07:458 + HLA14083 + Undefined + - + + + C*07:459 + HLA14118 + Undefined + - + + + C*07:460 + HLA14245 + Undefined + - + + + C*07:461 + HLA14246 + Undefined + - + + + C*07:462 + HLA14247 + Undefined + - + + + C*07:463 + HLA14248 + Undefined + - + + + C*07:464 + HLA14249 + Undefined + - + + + C*07:465 + HLA14251 + Undefined + - + + + C*07:466 + HLA14322 + Undefined + - + + + C*07:467 + HLA14323 + Undefined + - + + + C*07:468 + HLA14325 + Undefined + - + + + C*07:469 + HLA14326 + Undefined + - + + + C*07:470 + HLA14327 + Undefined + - + + + C*07:471 + HLA14328 + Undefined + - + + + C*07:472 + HLA14329 + Undefined + - + + + C*07:473 + HLA14330 + Undefined + - + + + C*07:474 + HLA14331 + Undefined + - + + + C*07:475 + HLA14332 + Undefined + - + + + C*07:476N + HLA14250 + NotExpressed + Null + + + C*07:477 + HLA14385 + Undefined + - + + + C*07:478 + HLA14394 + Undefined + - + + + C*07:479 + HLA14518 + Undefined + - + + + C*07:480 + HLA14521 + Undefined + - + + + C*07:481 + HLA14525 + Undefined + - + + + C*07:482 + HLA14526 + Undefined + - + + + C*07:483N + HLA14527 + NotExpressed + Null + + + C*07:484N + HLA14528 + NotExpressed + Null + + + C*07:485 + HLA14529 + Undefined + - + + + C*07:486 + HLA14458 + Undefined + - + + + C*07:487 + HLA14465 + Undefined + - + + + C*07:488 + HLA14602 + Undefined + - + + + C*07:489:01 + HLA14613 + Undefined + - + + + C*07:489:02 + HLA27858 + Undefined + - + + + C*07:490 + HLA14740 + Undefined + - + + + C*07:491:01N + HLA14741 + NotExpressed + Null + + + C*07:491:02N + HLA15145 + NotExpressed + Null + + + C*07:492 + HLA14742 + Undefined + - + + + C*07:493 + HLA14743 + Undefined + - + + + C*07:494Q + HLA14744 + Undefined + - + + + C*07:495 + HLA14745 + Undefined + - + + + C*07:496 + HLA14746 + Undefined + - + + + C*07:497 + HLA14747 + Undefined + - + + + C*07:498 + HLA14748 + Undefined + - + + + C*07:499 + HLA14817 + Undefined + - + + + C*07:500 + HLA14897 + Undefined + - + + + C*07:501 + HLA15039 + Undefined + - + + + C*07:502 + HLA15041 + Undefined + - + + + C*07:503 + HLA15042 + Undefined + - + + + C*07:504 + HLA15044 + Undefined + - + + + C*07:505 + HLA15045 + Undefined + - + + + C*07:506:01 + HLA15046 + Undefined + - + + + C*07:506:02 + HLA36249 + Undefined + - + + + C*07:507N + HLA15143 + NotExpressed + Null + + + C*07:508 + HLA15112 + Undefined + - + + + C*07:509 + HLA15124 + Undefined + - + + + C*07:510 + HLA15126 + Undefined + - + + + C*07:511 + HLA15128 + Undefined + - + + + C*07:512 + HLA15131 + Undefined + - + + + C*07:513Q + HLA15135 + Undefined + - + + + C*07:514:01 + HLA15136 + Undefined + - + + + C*07:514:02 + HLA31593 + Undefined + - + + + C*07:515 + HLA15299 + Undefined + - + + + C*07:516 + HLA15301 + Undefined + - + + + C*07:517 + HLA15170 + Undefined + - + + + C*07:518 + HLA15171 + Undefined + - + + + C*07:519 + HLA15173 + Undefined + - + + + C*07:520 + HLA15175 + Undefined + - + + + C*07:521:01 + HLA15190 + Undefined + - + + + C*07:521:02 + HLA19467 + Undefined + - + + + C*07:522 + HLA15192 + Undefined + - + + + C*07:523 + HLA15197 + Undefined + - + + + C*07:524 + HLA15198 + Undefined + - + + + C*07:525 + HLA15202 + Undefined + - + + + C*07:526:01 + HLA15204 + Undefined + - + + + C*07:526:02 + HLA19393 + Undefined + - + + + C*07:527 + HLA15211 + Undefined + - + + + C*07:528 + HLA15213 + Undefined + - + + + C*07:529 + HLA15218 + Undefined + - + + + C*07:530:01 + HLA15160 + Undefined + - + + + C*07:530:02 + HLA34191 + Undefined + - + + + C*07:531 + HLA15420 + Undefined + - + + + C*07:532 + HLA15471 + Undefined + - + + + C*07:533 + HLA15412 + Undefined + - + + + C*07:534 + HLA15650 + Undefined + - + + + C*07:535 + HLA15651 + Undefined + - + + + C*07:536 + HLA15652 + Undefined + - + + + C*07:537 + HLA15653 + Undefined + - + + + C*07:538 + HLA15654 + Undefined + - + + + C*07:539 + HLA15655 + Undefined + - + + + C*07:540 + HLA15656 + Undefined + - + + + C*07:541 + HLA15741 + Undefined + - + + + C*07:542 + HLA15742 + Undefined + - + + + C*07:543 + HLA15591 + Undefined + - + + + C*07:544 + HLA15589 + Undefined + - + + + C*07:545 + HLA15622 + Undefined + - + + + C*07:546 + HLA15792 + Undefined + - + + + C*07:547 + HLA15796 + Undefined + - + + + C*07:548 + HLA15797 + Undefined + - + + + C*07:549 + HLA15805 + Undefined + - + + + C*07:550 + HLA15811 + Undefined + - + + + C*07:551N + HLA15891 + NotExpressed + Null + + + C*07:552 + HLA15896 + Undefined + - + + + C*07:553 + HLA15898 + Undefined + - + + + C*07:554 + HLA15908 + Undefined + - + + + C*07:555 + HLA15912 + Undefined + - + + + C*07:556 + HLA15921 + Undefined + - + + + C*07:557 + HLA15935 + Undefined + - + + + C*07:558:01:01 + HLA15939 + Undefined + - + + + C*07:558:01:02 + HLA20702 + Undefined + - + + + C*07:559 + HLA15940 + Undefined + - + + + C*07:560 + HLA15942 + Undefined + - + + + C*07:561 + HLA15974 + Undefined + - + + + C*07:562 + HLA15975 + Undefined + - + + + C*07:563 + HLA15976 + Undefined + - + + + C*07:564 + HLA16271 + Undefined + - + + + C*07:565 + HLA16034 + Undefined + - + + + C*07:566 + HLA16041 + Undefined + - + + + C*07:567 + HLA16044 + Undefined + - + + + C*07:568 + HLA16344 + Undefined + - + + + C*07:569 + HLA16513 + Undefined + - + + + C*07:570 + HLA16514 + Undefined + - + + + C*07:571 + HLA16515 + Undefined + - + + + C*07:572 + HLA16516 + Undefined + - + + + C*07:573 + HLA16517 + Undefined + - + + + C*07:574 + HLA16518 + Undefined + - + + + C*07:575:01 + HLA16519 + Undefined + - + + + C*07:575:02 + HLA23338 + Undefined + - + + + C*07:576 + HLA16520 + Undefined + - + + + C*07:577 + HLA16521 + Undefined + - + + + C*07:578 + HLA16546 + Undefined + - + + + C*07:579 + HLA16619 + Undefined + - + + + C*07:580 + HLA16622 + Undefined + - + + + C*07:581 + HLA16763 + Undefined + - + + + C*07:582Q + HLA16764 + Undefined + - + + + C*07:583 + HLA16766 + Undefined + - + + + C*07:584 + HLA16732 + Undefined + - + + + C*07:585 + HLA16733 + Undefined + - + + + C*07:586 + HLA16734 + Undefined + - + + + C*07:587 + HLA16940 + Undefined + - + + + C*07:588 + HLA16869 + Undefined + - + + + C*07:589 + HLA17008 + Undefined + - + + + C*07:590 + HLA17096 + Undefined + - + + + C*07:591 + HLA17219 + Undefined + - + + + C*07:592 + HLA17275 + Undefined + - + + + C*07:593N + HLA17284 + NotExpressed + Null + + + C*07:594 + HLA17286 + Undefined + - + + + C*07:595 + HLA17288 + Undefined + - + + + C*07:596 + HLA17419 + Undefined + - + + + C*07:597 + HLA17420 + Undefined + - + + + C*07:598 + HLA17437 + Undefined + - + + + C*07:599 + HLA17506 + Undefined + - + + + C*07:600:01N + HLA17652 + NotExpressed + Null + + + C*07:600:02N + HLA17874 + NotExpressed + Null + + + C*07:601 + HLA17871 + Undefined + - + + + C*07:602 + HLA17873 + Undefined + - + + + C*07:603N + HLA17880 + NotExpressed + Null + + + C*07:604 + HLA17881 + Undefined + - + + + C*07:605 + HLA17882 + Undefined + - + + + C*07:606 + HLA17761 + Undefined + - + + + C*07:607 + HLA18012 + Undefined + - + + + C*07:608 + HLA18042 + Undefined + - + + + C*07:609 + HLA18044 + Undefined + - + + + C*07:610 + HLA18052 + Undefined + - + + + C*07:611 + HLA18182 + Undefined + - + + + C*07:612 + HLA18280 + Undefined + - + + + C*07:613 + HLA18283 + Undefined + - + + + C*07:614 + HLA18383 + Undefined + - + + + C*07:615 + HLA18386 + Undefined + - + + + C*07:616 + HLA18387 + Undefined + - + + + C*07:617 + HLA18400 + Undefined + - + + + C*07:618 + HLA18453 + Undefined + - + + + C*07:619 + HLA18454 + Undefined + - + + + C*07:620 + HLA18469 + Undefined + - + + + C*07:621 + HLA18476 + Undefined + - + + + C*07:622 + HLA18478 + Undefined + - + + + C*07:623 + HLA18480 + Undefined + - + + + C*07:624 + HLA18483 + Undefined + - + + + C*07:625 + HLA18487 + Undefined + - + + + C*07:626 + HLA18522 + Undefined + - + + + C*07:627 + HLA18524 + Undefined + - + + + C*07:628 + HLA18840 + Undefined + - + + + C*07:629 + HLA18854 + Undefined + - + + + C*07:630 + HLA18967 + Undefined + - + + + C*07:631 + HLA19015 + Undefined + - + + + C*07:632Q + HLA19053 + Undefined + - + + + C*07:633N + HLA19094 + NotExpressed + Null + + + C*07:634 + HLA19128 + Undefined + - + + + C*07:635 + HLA19200 + Undefined + - + + + C*07:636 + HLA19510 + Undefined + - + + + C*07:637 + HLA19241 + Undefined + - + + + C*07:638 + HLA19293 + Undefined + - + + + C*07:639 + HLA19341 + Undefined + - + + + C*07:640 + HLA19223 + Undefined + - + + + C*07:641 + HLA19400 + Undefined + - + + + C*07:642 + HLA19284 + Undefined + - + + + C*07:643 + HLA19208 + Undefined + - + + + C*07:644 + HLA19257 + Undefined + - + + + C*07:645 + HLA19427 + Undefined + - + + + C*07:646 + HLA19205 + Undefined + - + + + C*07:647 + HLA19386 + Undefined + - + + + C*07:648 + HLA19586 + Undefined + - + + + C*07:649 + HLA19550 + Undefined + - + + + C*07:650:01 + HLA19457 + Undefined + - + + + C*07:650:02 + HLA20475 + Undefined + - + + + C*07:651 + HLA19483 + Undefined + - + + + C*07:652 + HLA19522 + Undefined + - + + + C*07:653 + HLA19315 + Undefined + - + + + C*07:654 + HLA19408 + Undefined + - + + + C*07:655 + HLA19419 + Undefined + - + + + C*07:656 + HLA19538 + Undefined + - + + + C*07:657 + HLA19338 + Undefined + - + + + C*07:658 + HLA19546 + Undefined + - + + + C*07:659:01:01 + HLA19375 + Undefined + - + + + C*07:659:01:02 + HLA23103 + Undefined + - + + + C*07:660 + HLA19253 + Undefined + - + + + C*07:661 + HLA19216 + Undefined + - + + + C*07:662 + HLA19779 + Undefined + - + + + C*07:663Q + HLA19657 + Undefined + - + + + C*07:664 + HLA19858 + Undefined + - + + + C*07:665 + HLA19741 + Undefined + - + + + C*07:666 + HLA19615 + Undefined + - + + + C*07:667:01 + HLA19617 + Undefined + - + + + C*07:667:02 + HLA27114 + Undefined + - + + + C*07:668 + HLA19891 + Undefined + - + + + C*07:669 + HLA19690 + Undefined + - + + + C*07:670 + HLA19596 + Undefined + - + + + C*07:671 + HLA19644 + Undefined + - + + + C*07:672N + HLA19894 + NotExpressed + Null + + + C*07:673 + HLA19703 + Undefined + - + + + C*07:674 + HLA19855 + Undefined + - + + + C*07:675N + HLA20403 + NotExpressed + Null + + + C*07:676 + HLA20478 + Undefined + - + + + C*07:677 + HLA20301 + Undefined + - + + + C*07:678 + HLA19993 + Undefined + - + + + C*07:679 + HLA19969 + Undefined + - + + + C*07:680 + HLA20437 + Undefined + - + + + C*07:681 + HLA20200 + Undefined + - + + + C*07:682:01:01 + HLA19977 + Undefined + - + + + C*07:682:01:02 + HLA21202 + Undefined + - + + + C*07:682:02 + HLA20555 + Undefined + - + + + C*07:683 + HLA20418 + Undefined + - + + + C*07:684 + HLA19970 + Undefined + - + + + C*07:685 + HLA19985 + Undefined + - + + + C*07:686N + HLA20104 + NotExpressed + Null + + + C*07:687 + HLA20365 + Undefined + - + + + C*07:688 + HLA20072 + Undefined + - + + + C*07:689 + HLA20347 + Undefined + - + + + C*07:690N + HLA20030 + NotExpressed + Null + + + C*07:691 + HLA20366 + Undefined + - + + + C*07:692 + HLA20508 + Undefined + - + + + C*07:693 + HLA20124 + Undefined + - + + + C*07:694 + HLA20129 + Undefined + - + + + C*07:695:01:01 + HLA20325 + Undefined + - + + + C*07:695:01:02 + HLA20193 + Undefined + - + + + C*07:696 + HLA20272 + Undefined + - + + + C*07:697Q + HLA20374 + Undefined + - + + + C*07:698 + HLA20310 + Undefined + - + + + C*07:699 + HLA19982 + Undefined + - + + + C*07:700 + HLA20375 + Undefined + - + + + C*07:701 + HLA20485 + Undefined + - + + + C*07:702N + HLA20710 + NotExpressed + Null + + + C*07:703 + HLA21153 + Undefined + - + + + C*07:704 + HLA20954 + Undefined + - + + + C*07:705 + HLA20882 + Undefined + - + + + C*07:706 + HLA20626 + Undefined + - + + + C*07:707 + HLA20831 + Undefined + - + + + C*07:708 + HLA21097 + Undefined + - + + + C*07:709 + HLA21043 + Undefined + - + + + C*07:710 + HLA20895 + Undefined + - + + + C*07:711 + HLA21105 + Undefined + - + + + C*07:712 + HLA20725 + Undefined + - + + + C*07:713Q + HLA21111 + Undefined + - + + + C*07:714 + HLA20867 + Undefined + - + + + C*07:715:01 + HLA20900 + Undefined + - + + + C*07:715:02 + HLA28164 + Undefined + - + + + C*07:716 + HLA20849 + Undefined + - + + + C*07:717 + HLA21073 + Undefined + - + + + C*07:718 + HLA20577 + Undefined + - + + + C*07:719 + HLA20533 + Undefined + - + + + C*07:720 + HLA21185 + Undefined + - + + + C*07:721 + HLA21450 + Undefined + - + + + C*07:722 + HLA21538 + Undefined + - + + + C*07:723 + HLA21250 + Undefined + - + + + C*07:724 + HLA21904 + Undefined + - + + + C*07:725 + HLA21974 + Undefined + - + + + C*07:726N + HLA22131 + NotExpressed + Null + + + C*07:727 + HLA22153 + Undefined + - + + + C*07:728 + HLA22189 + Undefined + - + + + C*07:729:01:01 + HLA22082 + Undefined + - + + + C*07:729:01:02 + HLA26121 + Undefined + - + + + C*07:730 + HLA22125 + Undefined + - + + + C*07:731 + HLA22089 + Undefined + - + + + C*07:732 + HLA22186 + Undefined + - + + + C*07:733N + HLA22096 + NotExpressed + Null + + + C*07:734 + HLA22155 + Undefined + - + + + C*07:735 + HLA22044 + Undefined + - + + + C*07:736:01:01 + HLA22188 + Undefined + - + + + C*07:736:01:02 + HLA23085 + Undefined + - + + + C*07:737 + HLA22078 + Undefined + - + + + C*07:738 + HLA22013 + Undefined + - + + + C*07:739 + HLA22002 + Undefined + - + + + C*07:740 + HLA22176 + Undefined + - + + + C*07:741 + HLA22606 + Undefined + - + + + C*07:742 + HLA22401 + Undefined + - + + + C*07:743N + HLA22471 + NotExpressed + Null + + + C*07:744 + HLA22205 + Undefined + - + + + C*07:745N + HLA22238 + NotExpressed + Null + + + C*07:746N + HLA22568 + NotExpressed + Null + + + C*07:747N + HLA22316 + NotExpressed + Null + + + C*07:748 + HLA22282 + Undefined + - + + + C*07:749N + HLA22328 + NotExpressed + Null + + + C*07:750N + HLA22208 + NotExpressed + Null + + + C*07:751N + HLA22587 + NotExpressed + Null + + + C*07:752N + HLA22650 + NotExpressed + Null + + + C*07:753N + HLA22198 + NotExpressed + Null + + + C*07:754N + HLA22549 + NotExpressed + Null + + + C*07:755 + HLA22312 + Undefined + - + + + C*07:756 + HLA22273 + Undefined + - + + + C*07:757 + HLA22653 + Undefined + - + + + C*07:758 + HLA22292 + Undefined + - + + + C*07:759 + HLA22214 + Undefined + - + + + C*07:760 + HLA22370 + Undefined + - + + + C*07:761 + HLA22386 + Undefined + - + + + C*07:762 + HLA22317 + Undefined + - + + + C*07:763 + HLA22591 + Undefined + - + + + C*07:764 + HLA22204 + Undefined + - + + + C*07:765 + HLA22281 + Undefined + - + + + C*07:766 + HLA22516 + Undefined + - + + + C*07:767 + HLA22641 + Undefined + - + + + C*07:768 + HLA22593 + Undefined + - + + + C*07:769 + HLA22482 + Undefined + - + + + C*07:770N + HLA22423 + NotExpressed + Null + + + C*07:771 + HLA22547 + Undefined + - + + + C*07:772 + HLA22210 + Undefined + - + + + C*07:773N + HLA22601 + NotExpressed + Null + + + C*07:774 + HLA22621 + Undefined + - + + + C*07:775 + HLA22668 + Undefined + - + + + C*07:776N + HLA22789 + NotExpressed + Null + + + C*07:777 + HLA22683 + Undefined + - + + + C*07:778 + HLA22736 + Undefined + - + + + C*07:779:01:01 + HLA22732 + Undefined + - + + + C*07:779:01:02 + HLA31664 + Undefined + - + + + C*07:780 + HLA22926 + Undefined + - + + + C*07:781 + HLA23572 + Undefined + - + + + C*07:782 + HLA23305 + Undefined + - + + + C*07:783 + HLA23156 + Undefined + - + + + C*07:784 + HLA23729 + Undefined + - + + + C*07:785 + HLA23382 + Undefined + - + + + C*07:786 + HLA23617 + Undefined + - + + + C*07:787N + HLA23019 + NotExpressed + Null + + + C*07:788 + HLA23334 + Undefined + - + + + C*07:789 + HLA23232 + Undefined + - + + + C*07:790 + HLA23050 + Undefined + - + + + C*07:791 + HLA23523 + Undefined + - + + + C*07:792 + HLA23348 + Undefined + - + + + C*07:793 + HLA23574 + Undefined + - + + + C*07:794 + HLA23731 + Undefined + - + + + C*07:795 + HLA23511 + Undefined + - + + + C*07:796N + HLA23260 + NotExpressed + Null + + + C*07:797N + HLA23631 + NotExpressed + Null + + + C*07:798 + HLA23530 + Undefined + - + + + C*07:799 + HLA23748 + Undefined + - + + + C*07:800 + HLA23755 + Undefined + - + + + C*07:801 + HLA23659 + Undefined + - + + + C*07:802 + HLA23212 + Undefined + - + + + C*07:803 + HLA23460 + Undefined + - + + + C*07:804N + HLA23899 + NotExpressed + Null + + + C*07:805 + HLA23916 + Undefined + - + + + C*07:806 + HLA23986 + Undefined + - + + + C*07:807N + HLA24200 + NotExpressed + Null + + + C*07:808 + HLA23838 + Undefined + - + + + C*07:809 + HLA24276 + Undefined + - + + + C*07:810 + HLA24171 + Undefined + - + + + C*07:811 + HLA24229 + Undefined + - + + + C*07:812 + HLA24267 + Undefined + - + + + C*07:813 + HLA23919 + Undefined + - + + + C*07:814 + HLA24016 + Undefined + - + + + C*07:815 + HLA24278 + Undefined + - + + + C*07:816 + HLA24346 + Undefined + - + + + C*07:817 + HLA23928 + Undefined + - + + + C*07:818 + HLA24846 + Undefined + - + + + C*07:819Q + HLA25172 + Undefined + - + + + C*07:820N + HLA25552 + NotExpressed + Null + + + C*07:821N + HLA25359 + NotExpressed + Null + + + C*07:822 + HLA24594 + Undefined + - + + + C*07:823 + HLA25072 + Undefined + - + + + C*07:824 + HLA24866 + Undefined + - + + + C*07:825 + HLA24804 + Undefined + - + + + C*07:826 + HLA24795 + Undefined + - + + + C*07:827 + HLA24590 + Undefined + - + + + C*07:828 + HLA25831 + Undefined + - + + + C*07:829 + HLA25856 + Undefined + - + + + C*07:830 + HLA25616 + Undefined + - + + + C*07:831 + HLA26048 + Undefined + - + + + C*07:832 + HLA26062 + Undefined + - + + + C*07:833N + HLA25980 + NotExpressed + Null + + + C*07:834 + HLA25713 + Undefined + - + + + C*07:835 + HLA26147 + Undefined + - + + + C*07:836 + HLA26132 + Undefined + - + + + C*07:837 + HLA26155 + Undefined + - + + + C*07:838 + HLA26390 + Undefined + - + + + C*07:839N + HLA26296 + NotExpressed + Null + + + C*07:840N + HLA26313 + NotExpressed + Null + + + C*07:841 + HLA26243 + Undefined + - + + + C*07:842 + HLA26644 + Undefined + - + + + C*07:843 + HLA26638 + Undefined + - + + + C*07:844 + HLA26609 + Undefined + - + + + C*07:845 + HLA26738 + Undefined + - + + + C*07:846:01 + HLA27141 + Undefined + - + + + C*07:846:02 + HLA30552 + Undefined + - + + + C*07:847 + HLA27143 + Undefined + - + + + C*07:848 + HLA27147 + Undefined + - + + + C*07:849N + HLA27156 + NotExpressed + Null + + + C*07:850 + HLA27169 + Undefined + - + + + C*07:851 + HLA27183 + Undefined + - + + + C*07:852 + HLA27778 + Undefined + - + + + C*07:853 + HLA27577 + Undefined + - + + + C*07:854 + HLA27818 + Undefined + - + + + C*07:855 + HLA27822 + Undefined + - + + + C*07:856N + HLA27827 + NotExpressed + Null + + + C*07:857 + HLA27843 + Undefined + - + + + C*07:858 + HLA27867 + Undefined + - + + + C*07:859 + HLA27870 + Undefined + - + + + C*07:860 + HLA27874 + Undefined + - + + + C*07:861 + HLA27875 + Undefined + - + + + C*07:862 + HLA27884 + Undefined + - + + + C*07:863N + HLA28121 + NotExpressed + Null + + + C*07:864 + HLA28122 + Undefined + - + + + C*07:865 + HLA28123 + Undefined + - + + + C*07:866 + HLA28125 + Undefined + - + + + C*07:867 + HLA28126 + Undefined + - + + + C*07:868 + HLA28131 + Undefined + - + + + C*07:869 + HLA28138 + Undefined + - + + + C*07:870 + HLA28141 + Undefined + - + + + C*07:871 + HLA28143 + Undefined + - + + + C*07:872 + HLA28148 + Undefined + - + + + C*07:873 + HLA28150 + Undefined + - + + + C*07:874 + HLA28161 + Undefined + - + + + C*07:875 + HLA28170 + Undefined + - + + + C*07:876 + HLA28097 + Undefined + - + + + C*07:877 + HLA28099 + Undefined + - + + + C*07:878 + HLA28110 + Undefined + - + + + C*07:879 + HLA28112 + Undefined + - + + + C*07:880 + HLA28114 + Undefined + - + + + C*07:881N + HLA28389 + NotExpressed + Null + + + C*07:882 + HLA28270 + Undefined + - + + + C*07:883 + HLA28274 + Undefined + - + + + C*07:884 + HLA28300 + Undefined + - + + + C*07:885 + HLA28404 + Undefined + - + + + C*07:886N + HLA28447 + NotExpressed + Null + + + C*07:887 + HLA28453 + Undefined + - + + + C*07:888 + HLA28607 + Undefined + - + + + C*07:889N + HLA28500 + NotExpressed + Null + + + C*07:890 + HLA28504 + Undefined + - + + + C*07:891 + HLA28506 + Undefined + - + + + C*07:892 + HLA28514 + Undefined + - + + + C*07:893 + HLA28579 + Undefined + - + + + C*07:894 + HLA28891 + Undefined + - + + + C*07:895 + HLA28896 + Undefined + - + + + C*07:896 + HLA28833 + Undefined + - + + + C*07:897 + HLA28841 + Undefined + - + + + C*07:898 + HLA29276 + Undefined + - + + + C*07:899 + HLA29283 + Undefined + - + + + C*07:900 + HLA29257 + Undefined + - + + + C*07:901 + HLA29443 + Undefined + - + + + C*07:902 + HLA29490 + Undefined + - + + + C*07:903 + HLA29531 + Undefined + - + + + C*07:904 + HLA29478 + Undefined + - + + + C*07:905:01:01 + HLA29516 + Undefined + - + + + C*07:905:01:02 + HLA30563 + Undefined + - + + + C*07:906 + HLA29814 + Undefined + - + + + C*07:907 + HLA29799 + Undefined + - + + + C*07:908 + HLA30433 + Undefined + - + + + C*07:909 + HLA30231 + Undefined + - + + + C*07:910 + HLA30410 + Undefined + - + + + C*07:911 + HLA30045 + Undefined + - + + + C*07:912 + HLA29952 + Undefined + - + + + C*07:913 + HLA30038 + Undefined + - + + + C*07:914 + HLA29962 + Undefined + - + + + C*07:915 + HLA29996 + Undefined + - + + + C*07:916 + HLA30001 + Undefined + - + + + C*07:917 + HLA29987 + Undefined + - + + + C*07:918 + HLA29998 + Undefined + - + + + C*07:919 + HLA29978 + Undefined + - + + + C*07:920 + HLA29955 + Undefined + - + + + C*07:921 + HLA29956 + Undefined + - + + + C*07:922 + HLA29954 + Undefined + - + + + C*07:923 + HLA30044 + Undefined + - + + + C*07:924 + HLA30614 + Undefined + - + + + C*07:925 + HLA30746 + Undefined + - + + + C*07:926 + HLA30652 + Undefined + - + + + C*07:927 + HLA30679 + Undefined + - + + + C*07:928 + HLA30615 + Undefined + - + + + C*07:929 + HLA30711 + Undefined + - + + + C*07:930 + HLA30703 + Undefined + - + + + C*07:931 + HLA30678 + Undefined + - + + + C*07:932 + HLA30706 + Undefined + - + + + C*07:933 + HLA30710 + Undefined + - + + + C*07:934N + HLA30655 + NotExpressed + Null + + + C*07:935 + HLA30669 + Undefined + - + + + C*07:936N + HLA30566 + NotExpressed + Null + + + C*07:937 + HLA30664 + Undefined + - + + + C*07:938 + HLA30745 + Undefined + - + + + C*07:939 + HLA30640 + Undefined + - + + + C*07:940:01 + HLA30560 + Undefined + - + + + C*07:940:02 + HLA38558 + Undefined + - + + + C*07:941 + HLA30561 + Undefined + - + + + C*07:942 + HLA30572 + Undefined + - + + + C*07:943 + HLA30579 + Undefined + - + + + C*07:944 + HLA30764 + Undefined + - + + + C*07:945 + HLA30864 + Undefined + - + + + C*07:946 + HLA31208 + Undefined + - + + + C*07:947 + HLA31212 + Undefined + - + + + C*07:948 + HLA31104 + Undefined + - + + + C*07:949 + HLA31056 + Undefined + - + + + C*07:950 + HLA31008 + Undefined + - + + + C*07:951 + HLA31014 + Undefined + - + + + C*07:952 + HLA30943 + Undefined + - + + + C*07:953 + HLA31299 + Undefined + - + + + C*07:954N + HLA31244 + NotExpressed + Null + + + C*07:955 + HLA31384 + Undefined + - + + + C*07:956 + HLA31159 + Undefined + - + + + C*07:957 + HLA31145 + Undefined + - + + + C*07:958 + HLA31783 + Undefined + - + + + C*07:959 + HLA31707 + Undefined + - + + + C*07:960 + HLA31672 + Undefined + - + + + C*07:961 + HLA31582 + Undefined + - + + + C*07:962 + HLA31708 + Undefined + - + + + C*07:963N + HLA31611 + NotExpressed + Null + + + C*07:964 + HLA31530 + Undefined + - + + + C*07:965 + HLA31586 + Undefined + - + + + C*07:966 + HLA31585 + Undefined + - + + + C*07:967 + HLA31700 + Undefined + - + + + C*07:968 + HLA31608 + Undefined + - + + + C*07:969 + HLA31637 + Undefined + - + + + C*07:970N + HLA31891 + NotExpressed + Null + + + C*07:971 + HLA31966 + Undefined + - + + + C*07:972 + HLA31869 + Undefined + - + + + C*07:973 + HLA32010 + Undefined + - + + + C*07:974Q + HLA32069 + Undefined + - + + + C*07:975 + HLA32207 + Undefined + - + + + C*07:976 + HLA32493 + Undefined + - + + + C*07:977 + HLA32564 + Undefined + - + + + C*07:978 + HLA32510 + Undefined + - + + + C*07:979 + HLA32908 + Undefined + - + + + C*07:980 + HLA32833 + Undefined + - + + + C*07:981N + HLA33438 + NotExpressed + Null + + + C*07:982 + HLA32865 + Undefined + - + + + C*07:983 + HLA33376 + Undefined + - + + + C*07:984N + HLA33604 + NotExpressed + Null + + + C*07:985:01:01 + HLA33498 + Undefined + - + + + C*07:985:01:02Q + HLA36999 + Undefined + - + + + C*07:985:02 + HLA35026 + Undefined + - + + + C*07:986:01 + HLA33583 + Undefined + - + + + C*07:986:02 + HLA35792 + Undefined + - + + + 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C*08:02:01:24 + HLA26499 + Cw8 + Cw8 + + + C*08:02:01:25 + HLA27840 + Cw8 + Cw8 + + + C*08:02:01:26 + HLA27923 + Cw8 + Cw8 + + + C*08:02:01:27 + HLA28167 + Cw8 + Cw8 + + + C*08:02:01:28 + HLA28108 + Cw8 + Cw8 + + + C*08:02:01:29 + HLA28475 + Cw8 + Cw8 + + + C*08:02:01:30 + HLA28368 + Cw8 + Cw8 + + + C*08:02:01:31 + HLA28660 + Cw8 + Cw8 + + + C*08:02:01:32 + HLA29626 + Cw8 + Cw8 + + + C*08:02:01:33 + HLA30323 + Cw8 + Cw8 + + + C*08:02:01:34 + HLA30573 + Cw8 + Cw8 + + + C*08:02:01:35 + HLA32713 + Cw8 + Cw8 + + + C*08:02:01:36 + HLA33016 + Cw8 + Cw8 + + + C*08:02:01:37 + HLA32933 + Cw8 + Cw8 + + + C*08:02:01:38 + HLA32670 + Cw8 + Cw8 + + + C*08:02:01:39 + HLA33005 + Cw8 + Cw8 + + + C*08:02:01:40 + HLA32650 + Cw8 + Cw8 + + + C*08:02:01:41 + HLA33032 + Cw8 + Cw8 + + + C*08:02:01:42 + HLA38424 + Cw8 + Cw8 + + + C*08:02:02 + HLA04345 + Cw8 + Cw8 + + + C*08:02:03 + HLA04392 + Cw8 + Cw8 + + + C*08:02:04 + HLA05309 + Cw8 + Cw8 + + + C*08:02:05 + HLA05591 + Cw8 + Cw8 + + + C*08:02:06 + HLA06413 + Cw8 + Cw8 + + + C*08:02:07 + HLA07273 + Cw8 + Cw8 + + + C*08:02:08 + HLA08753 + Cw8 + Cw8 + + + C*08:02:09 + HLA09026 + Cw8 + Cw8 + + + C*08:02:10 + HLA09194 + Cw8 + Cw8 + + + C*08:02:11:01 + HLA11258 + Cw8 + Cw8 + + + C*08:02:11:02 + HLA29612 + Cw8 + Cw8 + + + C*08:02:12 + HLA12720 + Cw8 + Cw8 + + + C*08:02:13 + HLA15169 + Cw8 + Cw8 + + + C*08:02:14 + HLA15203 + Cw8 + Cw8 + + + C*08:02:15 + HLA17273 + Cw8 + Cw8 + + + C*08:02:16 + HLA18389 + Cw8 + Cw8 + + + C*08:02:17 + HLA18479 + Cw8 + Cw8 + + + C*08:02:18 + HLA19893 + Cw8 + Cw8 + + + C*08:02:19 + HLA19796 + Cw8 + Cw8 + + + C*08:02:20 + HLA19860 + Cw8 + Cw8 + + + C*08:02:21 + HLA20465 + Cw8 + Cw8 + + + C*08:02:22 + HLA20318 + Cw8 + Cw8 + + + C*08:02:23 + HLA21400 + Cw8 + Cw8 + + + C*08:02:24 + HLA22490 + Cw8 + Cw8 + + + C*08:02:25 + HLA22573 + Cw8 + Cw8 + + + C*08:02:26 + HLA22612 + Cw8 + Cw8 + + + C*08:02:27 + HLA24024 + Cw8 + Cw8 + + + C*08:02:28 + HLA25871 + Cw8 + Cw8 + + + C*08:02:29 + HLA25838 + Cw8 + Cw8 + + + C*08:02:30 + HLA28152 + Cw8 + Cw8 + + + C*08:02:31 + HLA29568 + Cw8 + Cw8 + + + C*08:02:32 + HLA29967 + Cw8 + Cw8 + + + C*08:02:33 + HLA30547 + Cw8 + Cw8 + + + C*08:02:34 + HLA31563 + Cw8 + Cw8 + + + C*08:02:35 + HLA33508 + Cw8 + Cw8 + + + C*08:02:36 + HLA34414 + Cw8 + Cw8 + + + C*08:02:37 + HLA35072 + Cw8 + Cw8 + + + C*08:02:38:01 + HLA35375 + Cw8 + Cw8 + + + C*08:02:38:02 + HLA37819 + Cw8 + Cw8 + + + C*08:02:39 + HLA37087 + Cw8 + Cw8 + + + C*08:03:01:01 + HLA00447 + Cw8 + Cw8 + + + C*08:03:01:02 + HLA29378 + Cw8 + Cw8 + + + C*08:03:01:03 + HLA33161 + Cw8 + Cw8 + + + C*08:03:01:04 + HLA33186 + Cw8 + Cw8 + + + C*08:03:02 + HLA03758 + Cw8 + Cw8 + + + C*08:03:03 + HLA10622 + Cw8 + Cw8 + + + C*08:03:04 + HLA15201 + Cw8 + Cw8 + + + C*08:03:05 + HLA34422 + Cw8 + Cw8 + + + C*08:04:01:01 + HLA00448 + Cw8 + Cw8 + + + C*08:04:01:02 + HLA22812 + Cw8 + Cw8 + + + C*08:04:01:03 + HLA34879 + Cw8 + Cw8 + + + C*08:04:02 + HLA07521 + Cw8 + Cw8 + + + C*08:04:03 + HLA08740 + Cw8 + Cw8 + + + C*08:05 + HLA00449 + Cw8 + - + + + C*08:06 + HLA00450 + Cw8 + - + + + C*08:07 + HLA01136 + Cw8 + - + + + C*08:08:01 + HLA01238 + Cw8 + - + + + C*08:08:02 + HLA10617 + Cw8 + - + + + C*08:09 + HLA01322 + Cw8 + - + + + C*08:10 + HLA01835 + Undefined + - + + + C*08:11 + HLA01857 + Undefined + - + + + C*08:12:01:01 + HLA01879 + Cw8 + - + + + C*08:12:01:02 + HLA25236 + Cw8 + - + + + C*08:13 + HLA02302 + Cw8 + - + + + C*08:14 + HLA02445 + Cw8 + - + + + C*08:15:01 + HLA03017 + Undefined + - + + + C*08:15:02 + HLA06138 + Undefined + - + + + C*08:16:01 + HLA03280 + Undefined + - + + + C*08:16:02 + HLA07742 + Undefined + - + + + C*08:17 + HLA03420 + Undefined + - + + + C*08:18 + HLA03440 + Undefined + - + + + C*08:19:01 + HLA03482 + Undefined + - + + + C*08:19:02 + HLA18086 + Undefined + - + + + C*08:20 + HLA03632 + Undefined + - + + + C*08:21 + HLA03626 + Undefined + - + + + C*08:22:01:01 + HLA03680 + Undefined + - + + + C*08:22:01:02 + HLA24194 + Undefined + - + + + C*08:22:02 + HLA08159 + Undefined + - + + + C*08:23 + HLA03696 + Undefined + - + + + C*08:24 + HLA03763 + Undefined + - + + + C*08:25 + HLA03767 + Undefined + - + + + C*08:26N + HLA03818 + NotExpressed + Null + + + C*08:27 + HLA03975 + Undefined + - + + + C*08:28 + HLA04319 + Undefined + - + + + C*08:29 + HLA04332 + Undefined + - + + + C*08:30 + HLA04393 + Undefined + - + + + C*08:31 + HLA04583 + Undefined + - + + + C*08:32 + HLA05180 + Undefined + - + + + C*08:33:01 + HLA05188 + Undefined + - + + + C*08:33:02 + HLA07053 + Undefined + - + + + C*08:33:03 + HLA08201 + Undefined + - + + + C*08:33:04 + HLA23664 + Undefined + - + + + C*08:33:05 + HLA33656 + Undefined + - + + + C*08:33:06 + HLA37748 + Undefined + - + + + C*08:34 + HLA05196 + Undefined + - + + + C*08:35 + HLA05395 + Undefined + - + + + C*08:36N + HLA05416 + NotExpressed + Null + + + C*08:37 + HLA05579 + Undefined + - + + + C*08:38 + HLA05616 + Undefined + - + + + C*08:39 + HLA05753 + Undefined + - + + + C*08:40 + HLA05785 + Undefined + - + + + C*08:41 + HLA05790 + Undefined + - + + + C*08:42 + HLA05863 + Undefined + - + + + C*08:43 + HLA05874 + Undefined + - + + + C*08:44 + HLA05890 + Undefined + - + + + C*08:45 + HLA06072 + Undefined + - + + + C*08:46 + HLA06173 + Undefined + - + + + C*08:47 + HLA06393 + Undefined + - + + + C*08:48 + HLA06394 + Undefined + - + + + C*08:49 + HLA06412 + Undefined + - + + + C*08:50 + HLA06428 + Undefined + - + + + C*08:51 + HLA06721 + Undefined + - + + + C*08:52N + HLA06814 + NotExpressed + Null + + + C*08:53 + HLA07050 + Undefined + - + + + C*08:54 + HLA07110 + Undefined + - + + + C*08:55N + HLA07345 + NotExpressed + Null + + + C*08:56 + HLA07363 + Undefined + - + + + C*08:57 + HLA07489 + Undefined + - + + + C*08:58 + HLA07530 + Undefined + - + + + C*08:59 + HLA07531 + Undefined + - + + + C*08:60 + HLA07743 + Undefined + - + + + C*08:61 + HLA07847 + Undefined + - + + + C*08:62:01 + HLA07938 + Undefined + - + + + C*08:62:02 + HLA18385 + Undefined + - + + + C*08:63 + HLA08088 + Undefined + - + + + C*08:65 + HLA08400 + Undefined + - + + + C*08:66 + HLA08427 + Undefined + - + + + C*08:67 + HLA08728 + Undefined + - + + + C*08:68 + HLA08729 + Undefined + - + + + C*08:69 + HLA08731 + Undefined + - + + + C*08:70Q + HLA08738 + Undefined + - + + + C*08:71 + HLA08739 + Undefined + - + + + C*08:72:01 + HLA08741 + Undefined + - + + + C*08:72:02 + HLA09610 + Undefined + - + + + C*08:73 + HLA09023 + Undefined + - + + + C*08:74 + HLA09051 + Undefined + - + + + C*08:75 + HLA09165 + Undefined + - + + + C*08:76 + HLA09166 + Undefined + - + + + C*08:77 + HLA09193 + Undefined + - + + + C*08:78 + HLA09683 + Undefined + - + + + C*08:79 + HLA10006 + Undefined + - + + + C*08:80 + HLA10008 + Undefined + - + + + C*08:81 + HLA10010 + Undefined + - + + + C*08:82 + HLA10013 + Undefined + - + + + C*08:83 + HLA10018 + Undefined + - + + + C*08:84 + HLA10019 + Undefined + - + + + C*08:85 + HLA10020 + Undefined + - + + + C*08:86 + HLA10021 + Undefined + - + + + C*08:87 + HLA10022 + Undefined + - + + + C*08:88N + HLA10023 + NotExpressed + Null + + + C*08:89N + HLA10024 + NotExpressed + Null + + + C*08:90 + HLA10077 + Undefined + - + + + C*08:91 + HLA10078 + Undefined + - + + + C*08:92 + HLA10080 + Undefined + - + + + C*08:93 + HLA10081 + Undefined + - + + + C*08:94 + HLA10260 + Undefined + - + + + C*08:95 + HLA10615 + Undefined + - + + + C*08:96 + HLA10616 + Undefined + - + + + C*08:97 + HLA10618 + Undefined + - + + + C*08:98 + HLA10580 + Undefined + - + + + C*08:99 + HLA10619 + Undefined + - + + + C*08:100 + HLA10620 + Undefined + - + + + C*08:101 + HLA10621 + Undefined + - + + + C*08:102 + HLA10623 + Undefined + - + + + C*08:103:01:01 + HLA10915 + Undefined + - + + + C*08:103:01:02 + HLA33411 + Undefined + - + + + C*08:104 + HLA10918 + Undefined + - + + + C*08:105 + HLA11091 + Undefined + - + + + C*08:106 + HLA11559 + Undefined + - + + + C*08:107 + HLA11859 + Undefined + - + + + C*08:108 + HLA11860 + Undefined + - + + + C*08:109 + HLA11866 + Undefined + - + + + C*08:110 + HLA11957 + Undefined + - + + + C*08:111 + HLA11958 + Undefined + - + + + C*08:112 + HLA12147 + Undefined + - + + + C*08:113 + HLA12613 + Undefined + - + + + C*08:114 + HLA12857 + Undefined + - + + + C*08:115 + HLA12859 + Undefined + - + + + C*08:116 + HLA13044 + Undefined + - + + + C*08:117 + HLA13098 + Undefined + - + + + C*08:118 + HLA13195 + Undefined + - + + + C*08:119 + HLA13269 + Undefined + - + + + C*08:120 + HLA13563 + Undefined + - + + + C*08:121N + HLA13499 + NotExpressed + Null + + + C*08:122 + HLA13750 + Undefined + - + + + C*08:123 + HLA13751 + Undefined + - + + + C*08:124 + HLA13873 + Undefined + - + + + C*08:125 + HLA14116 + Undefined + - + + + C*08:126 + HLA14253 + Undefined + - + + + C*08:127N + HLA14203 + NotExpressed + Null + + + C*08:128 + HLA14401 + Undefined + - + + + C*08:129N + HLA14604 + NotExpressed + Null + + + C*08:130N + HLA14750 + NotExpressed + Null + + + C*08:131 + HLA15049 + Undefined + - + + + C*08:132 + HLA15031 + Undefined + - + + + C*08:133 + HLA15294 + Undefined + - + + + C*08:134 + HLA15302 + Undefined + - + + + C*08:135 + HLA15304 + Undefined + - + + + C*08:136 + HLA15305 + Undefined + - + + + C*08:137 + HLA15658 + Undefined + - + + + C*08:138 + HLA15791 + Undefined + - + + + C*08:139 + HLA15799 + Undefined + - + + + C*08:140 + HLA15890 + Undefined + - + + + C*08:141Q + HLA15894 + Undefined + - + + + C*08:142 + HLA15928 + Undefined + - + + + C*08:143 + HLA15979 + Undefined + - + + + C*08:144:01 + HLA16525 + Undefined + - + + + C*08:144:02 + HLA18388 + Undefined + - + + + C*08:145 + HLA16526 + Undefined + - + + + C*08:146 + HLA16527 + Undefined + - + + + C*08:147 + HLA16735 + Undefined + - + + + C*08:148 + HLA16830 + Undefined + - + + + C*08:149 + HLA16942 + Undefined + - + + + C*08:150 + HLA17011 + Undefined + - + + + C*08:151 + HLA17012 + Undefined + - + + + C*08:152 + HLA17508 + Undefined + - + + + C*08:153 + HLA17509 + Undefined + - + + + C*08:154 + HLA17606 + Undefined + - + + + C*08:155 + HLA17884 + Undefined + - + + + C*08:156 + HLA17886 + Undefined + - + + + C*08:157 + HLA17887 + Undefined + - + + + C*08:158 + HLA18049 + Undefined + - + + + C*08:159 + HLA18074 + Undefined + - + + + C*08:160 + HLA18157 + Undefined + - + + + C*08:161N + HLA18183 + NotExpressed + Null + + + C*08:162 + HLA18380 + Undefined + - + + + C*08:163 + HLA18392 + Undefined + - + + + C*08:164 + HLA18488 + Undefined + - + + + C*08:165 + HLA18569 + Undefined + - + + + C*08:166 + HLA18515 + Undefined + - + + + C*08:167 + HLA18859 + Undefined + - + + + C*08:168 + HLA19404 + Undefined + - + + + C*08:169 + HLA19339 + Undefined + - + + + C*08:170 + HLA20438 + Undefined + - + + + C*08:171 + HLA20502 + Undefined + - + + + C*08:172 + HLA20102 + Undefined + - + + + C*08:173N + HLA20358 + NotExpressed + Null + + + C*08:174 + HLA20681 + Undefined + - + + + C*08:175 + HLA21569 + Undefined + - + + + C*08:176 + HLA21359 + Undefined + - + + + C*08:177 + HLA21473 + Undefined + - + + + C*08:178 + HLA21667 + Undefined + - + + + C*08:179 + HLA22119 + Undefined + - + + + C*08:180N + HLA22287 + NotExpressed + Null + + + C*08:181N + HLA22618 + NotExpressed + Null + + + C*08:182 + HLA22326 + Undefined + - + + + C*08:183 + HLA22248 + Undefined + - + + + C*08:184 + HLA22237 + Undefined + - + + + C*08:185 + HLA22466 + Undefined + - + + + C*08:186 + HLA22221 + Undefined + - + + + C*08:187 + HLA22505 + Undefined + - + + + C*08:188 + HLA22793 + Undefined + - + + + C*08:189 + HLA22776 + Undefined + - + + + C*08:190 + HLA22804 + Undefined + - + + + C*08:191 + HLA23736 + Undefined + - + + + C*08:192 + HLA23262 + Undefined + - + + + C*08:193 + HLA23415 + Undefined + - + + + C*08:194 + HLA23763 + Undefined + - + + + C*08:195 + HLA23441 + Undefined + - + + + C*08:196 + HLA23593 + Undefined + - + + + C*08:197 + HLA23965 + Undefined + - + + + C*08:198 + HLA24145 + Undefined + - + + + C*08:199 + HLA24027 + Undefined + - + + + C*08:200 + HLA24240 + Undefined + - + + + C*08:201 + HLA25387 + Undefined + - + + + C*08:202 + HLA25727 + Undefined + - + + + C*08:203 + HLA25963 + Undefined + - + + + C*08:204 + HLA26145 + Undefined + - + + + C*08:205 + HLA26209 + Undefined + - + + + C*08:206 + HLA26164 + Undefined + - + + + C*08:207:01 + HLA26654 + Undefined + - + + + C*08:207:02 + HLA37038 + Undefined + - + + + C*08:208N + HLA26829 + NotExpressed + Null + + + C*08:209 + HLA27173 + Undefined + - + + + C*08:210 + HLA27515 + Undefined + - + + + C*08:211 + HLA27568 + Undefined + - + + + C*08:212 + HLA27866 + Undefined + - + + + C*08:213 + HLA28147 + Undefined + - + + + C*08:214N + HLA28375 + NotExpressed + Null + + + C*08:215 + HLA28273 + Undefined + - + + + C*08:216 + HLA28276 + Undefined + - + + + C*08:217 + HLA29014 + Undefined + - + + + C*08:218 + HLA29186 + Undefined + - + + + C*08:219 + HLA29384 + Undefined + - + + + C*08:220 + HLA29529 + Undefined + - + + + C*08:221 + HLA30179 + Undefined + - + + + C*08:222 + HLA30030 + Undefined + - + + + C*08:223 + HLA29912 + Undefined + - + + + C*08:224N + HLA30750 + NotExpressed + Null + + + C*08:225Q + HLA30569 + Undefined + - + + + C*08:226 + HLA31141 + Undefined + - + + + C*08:227 + HLA31178 + Undefined + - + + + C*08:228 + HLA31758 + Undefined + - + + + C*08:229 + HLA31572 + Undefined + - + + + C*08:230 + HLA31691 + Undefined + - + + + C*08:231 + HLA31541 + Undefined + - + + + C*08:232 + HLA31694 + Undefined + - + + + C*08:233 + HLA32000 + Undefined + - + + + C*08:234 + HLA33035 + Undefined + - + + + C*08:235 + HLA32897 + Undefined + - + + + C*08:236N + HLA33533 + NotExpressed + Null + + + C*08:237 + HLA33528 + Undefined + - + + + C*08:238 + HLA33692 + Undefined + - + + + C*08:239 + HLA33676 + Undefined + - + + + C*08:240 + HLA34167 + Undefined + - + + + C*08:241 + HLA34331 + Undefined + - + + + C*08:242 + HLA34433 + Undefined + - + + + C*08:243 + HLA34283 + Undefined + - + + + C*08:244 + HLA35208 + Undefined + - + + + C*08:245 + HLA34973 + Undefined + - + + + C*08:246 + HLA35214 + Undefined + - + + + C*08:247 + HLA35336 + Undefined + - + + + C*08:248 + HLA34907 + Undefined + - + + + C*08:249 + HLA34857 + Undefined + - + + + C*08:250 + HLA35258 + Undefined + - + + + C*08:251 + HLA35587 + Undefined + - + + + C*08:252 + HLA35859 + Undefined + - + + + C*08:253 + HLA35804 + Undefined + - + + + C*08:254 + HLA35862 + Undefined + - + + + C*08:255 + HLA35918 + Undefined + - + + + C*08:256 + HLA35665 + Undefined + - + + + C*08:257 + HLA36428 + Undefined + - + + + C*08:258 + HLA36788 + Undefined + - + + + C*08:259 + HLA36673 + Undefined + - + + + C*08:260 + HLA36699 + Undefined + - + + + C*08:261 + HLA36857 + Undefined + - + + + C*08:262 + HLA36944 + Undefined + - + + + C*08:263 + HLA37282 + Undefined + - + + + C*08:264 + HLA37356 + Undefined + - + + + C*08:265 + HLA37462 + Undefined + - + + + C*08:266 + HLA37413 + Undefined + - + + + C*08:267 + HLA37873 + Undefined + - + + + C*08:268 + HLA37858 + Undefined + - + + + C*08:269 + HLA37798 + Undefined + - + + + C*08:270 + HLA37900 + Undefined + - + + + C*12:02:01 + HLA00453 + Undefined + - + + + C*12:02:02:01 + HLA00454 + Undefined + - + + + C*12:02:02:02 + HLA16274 + Undefined + - + + + C*12:02:02:03 + HLA17159 + Undefined + - + + + C*12:02:02:04 + HLA24411 + Undefined + - + + + C*12:02:02:05 + HLA25335 + Undefined + - + + + C*12:02:02:06 + HLA24790 + Undefined + - + + + C*12:02:02:07 + HLA25914 + Undefined + - + + + C*12:02:02:08 + HLA26169 + Undefined + - + + + C*12:02:02:09 + HLA27146 + Undefined + - + + + C*12:02:02:10 + HLA27596 + Undefined + - + + + C*12:02:02:11 + HLA27907 + Undefined + - + + + C*12:02:02:12 + HLA29422 + Undefined + - + + + C*12:02:02:13 + HLA30338 + Undefined + - + + + C*12:02:02:14 + HLA30328 + Undefined + - + + + C*12:02:02:15 + HLA30440 + Undefined + - + + + C*12:02:02:16 + HLA33478 + Undefined + - + + + C*12:02:02:17 + HLA33326 + Undefined + - + + + C*12:02:02:18 + HLA33075 + Undefined + - + + + C*12:02:02:19 + HLA32862 + Undefined + - + + + C*12:02:02:20 + HLA32915 + Undefined + - + + + C*12:02:02:21 + HLA33368 + Undefined + - + + + C*12:02:02:22 + HLA36232 + Undefined + - + + + C*12:02:02:23 + HLA37316 + Undefined + - + + + C*12:02:02:24Q + HLA37420 + Undefined + - + + + C*12:02:02:25 + HLA38502 + Undefined + - + + + C*12:02:03 + HLA01145 + Undefined + - + + + C*12:02:04 + HLA04620 + Undefined + - + + + C*12:02:05 + HLA04858 + Undefined + - + + + C*12:02:06 + HLA05178 + Undefined + - + + + C*12:02:07 + HLA07137 + Undefined + - + + + C*12:02:08 + HLA07555 + Undefined + - + + + C*12:02:09 + HLA07785 + Undefined + - + + + C*12:02:10 + HLA10130 + Undefined + - + + + C*12:02:11 + HLA10435 + Undefined + - + + + C*12:02:12 + HLA11661 + Undefined + - + + + C*12:02:13 + HLA12336 + Undefined + - + + + C*12:02:14 + HLA15132 + Undefined + - + + + C*12:02:15 + HLA16038 + Undefined + - + + + C*12:02:16 + HLA18390 + Undefined + - + + + C*12:02:17 + HLA18571 + Undefined + - + + + C*12:02:18 + HLA18656 + Undefined + - + + + C*12:02:19 + HLA18752 + Undefined + - + + + C*12:02:20 + HLA19248 + Undefined + - + + + C*12:02:21 + HLA19870 + Undefined + - + + + C*12:02:22 + HLA20395 + Undefined + - + + + C*12:02:23 + HLA19967 + Undefined + - + + + C*12:02:24 + HLA21150 + Undefined + - + + + C*12:02:25 + HLA21535 + Undefined + - + + + C*12:02:26 + HLA22058 + Undefined + - + + + C*12:02:27 + HLA22439 + Undefined + - + + + C*12:02:28 + HLA22455 + Undefined + - + + + C*12:02:29 + HLA22560 + Undefined + - + + + C*12:02:30 + HLA23207 + Undefined + - + + + C*12:02:31 + HLA23558 + Undefined + - + + + C*12:02:32 + HLA23426 + Undefined + - + + + C*12:02:33 + HLA25166 + Undefined + - + + + C*12:02:34 + HLA26112 + Undefined + - + + + C*12:02:35 + HLA26344 + Undefined + - + + + C*12:02:36 + HLA26602 + Undefined + - + + + C*12:02:37 + HLA27177 + Undefined + - + + + C*12:02:38 + HLA27613 + Undefined + - + + + C*12:02:39 + HLA28280 + Undefined + - + + + C*12:02:40 + HLA30294 + Undefined + - + + + C*12:02:41 + HLA29982 + Undefined + - + + + C*12:02:42 + HLA30031 + Undefined + - + + + C*12:02:43 + HLA31039 + Undefined + - + + + C*12:02:44 + HLA33606 + Undefined + - + + + C*12:02:45 + HLA33662 + Undefined + - + + + C*12:02:46 + HLA34155 + Undefined + - + + + C*12:02:47 + HLA35461 + Undefined + - + + + C*12:02:48 + HLA36061 + Undefined + - + + + C*12:02:49 + HLA36708 + Undefined + - + + + C*12:02:50 + HLA37473 + Undefined + - + + + C*12:02:51 + HLA37781 + Undefined + - + + + C*12:02:52 + HLA38559 + Undefined + - + + + C*12:03:01:01 + HLA00455 + Undefined + - + + + C*12:03:01:02 + HLA02766 + Undefined + - + + + C*12:03:01:03 + HLA14194 + Undefined + - + + + C*12:03:01:04 + HLA15032 + Undefined + - + + + C*12:03:01:05 + HLA15946 + Undefined + - + + + C*12:03:01:06 + HLA15907 + Undefined + - + + + C*12:03:01:07 + HLA16176 + Undefined + - + + + C*12:03:01:08 + HLA17050 + Undefined + - + + + C*12:03:01:09 + HLA17073 + Undefined + - + + + C*12:03:01:10 + HLA18265 + Undefined + - + + + C*12:03:01:11 + HLA19016 + Undefined + - + + + C*12:03:01:12 + HLA19017 + Undefined + - + + + C*12:03:01:13 + HLA19018 + Undefined + - + + + C*12:03:01:14 + HLA24712 + Undefined + - + + + C*12:03:01:15 + HLA24607 + Undefined + - + + + C*12:03:01:16 + HLA24662 + Undefined + - + + + C*12:03:01:17 + HLA25280 + Undefined + - + + + C*12:03:01:18 + HLA24653 + Undefined + - + + + C*12:03:01:19 + HLA24932 + Undefined + - + + + C*12:03:01:20 + HLA24500 + Undefined + - + + + C*12:03:01:21 + HLA25228 + Undefined + - + + + C*12:03:01:22 + HLA24427 + Undefined + - + + + C*12:03:01:23 + HLA24745 + Undefined + - + + + C*12:03:01:24 + HLA24690 + Undefined + - + + + C*12:03:01:25 + HLA25021 + Undefined + - + + + C*12:03:01:26 + HLA25144 + Undefined + - + + + C*12:03:01:27 + HLA25292 + Undefined + - + + + C*12:03:01:28 + HLA24833 + Undefined + - + + + C*12:03:01:29 + HLA24508 + Undefined + - + + + C*12:03:01:30 + HLA25439 + Undefined + - + + + C*12:03:01:31 + HLA25845 + Undefined + - + + + C*12:03:01:32 + HLA25627 + Undefined + - + + + C*12:03:01:33 + HLA27255 + Undefined + - + + + C*12:03:01:34 + HLA27769 + Undefined + - + + + C*12:03:01:35 + HLA27587 + Undefined + - + + + C*12:03:01:36 + HLA28146 + Undefined + - + + + C*12:03:01:37 + HLA28478 + Undefined + - + + + C*12:03:01:38 + HLA28667 + Undefined + - + + + C*12:03:01:39 + HLA29237 + Undefined + - + + + C*12:03:01:40 + HLA30239 + Undefined + - + + + C*12:03:01:41 + HLA30326 + Undefined + - + + + C*12:03:01:42Q + HLA29961 + Undefined + - + + + C*12:03:01:43 + HLA32032 + Undefined + - + + + C*12:03:01:44 + HLA32414 + Undefined + - + + + C*12:03:01:45 + HLA33055 + Undefined + - + + + C*12:03:01:46 + HLA33158 + Undefined + - + + + C*12:03:01:47 + HLA33212 + Undefined + - + + + C*12:03:01:48 + HLA32863 + Undefined + - + + + C*12:03:01:49 + HLA33444 + Undefined + - + + + C*12:03:01:50 + HLA33297 + Undefined + - + + + C*12:03:01:51 + HLA32815 + Undefined + - + + + C*12:03:01:52 + HLA33201 + Undefined + - + + + C*12:03:01:53 + HLA33250 + Undefined + - + + + C*12:03:01:54 + HLA32898 + Undefined + - + + + C*12:03:01:55 + HLA33332 + Undefined + - + + + C*12:03:01:56 + HLA33226 + Undefined + - + + + C*12:03:01:57 + HLA33421 + Undefined + - + + + C*12:03:01:58 + HLA32916 + Undefined + - + + + C*12:03:01:59 + HLA33105 + Undefined + - + + + C*12:03:01:60 + HLA32818 + Undefined + - + + + C*12:03:01:61 + HLA33822 + Undefined + - + + + C*12:03:01:62 + HLA38381 + Undefined + - + + + C*12:03:01:63 + HLA38403 + Undefined + - + + + C*12:03:01:64 + HLA38112 + Undefined + - + + + C*12:03:02 + HLA01315 + Undefined + - + + + C*12:03:03 + HLA01885 + Undefined + - + + + C*12:03:04 + HLA02428 + Undefined + - + + + C*12:03:05 + HLA03127 + Undefined + - + + + C*12:03:06 + HLA03285 + Undefined + - + + + C*12:03:07 + HLA04326 + Undefined + - + + + C*12:03:08 + HLA04337 + Undefined + - + + + C*12:03:09 + HLA04600 + Undefined + - + + + C*12:03:10 + HLA04836 + Undefined + - + + + C*12:03:11 + HLA04840 + Undefined + - + + + C*12:03:12 + HLA05172 + Undefined + - + + + C*12:03:13 + HLA05565 + Undefined + - + + + C*12:03:14 + HLA05623 + Undefined + - + + + C*12:03:15 + HLA06001 + Undefined + - + + + C*12:03:16 + HLA06415 + Undefined + - + + + C*12:03:17 + HLA07064 + Undefined + - + + + C*12:03:18 + HLA07123 + Undefined + - + + + C*12:03:19 + HLA07230 + Undefined + - + + + C*12:03:20 + HLA07318 + Undefined + - + + + C*12:03:21 + HLA07853 + Undefined + - + + + C*12:03:22 + HLA07855 + Undefined + - + + + C*12:03:23 + HLA08535 + Undefined + - + + + C*12:03:24 + HLA08742 + Undefined + - + + + C*12:03:25 + HLA08752 + Undefined + - + + + C*12:03:26 + HLA10082 + Undefined + - + + + C*12:03:27 + HLA10088 + Undefined + - + + + C*12:03:28 + HLA10135 + Undefined + - + + + C*12:03:29 + HLA10434 + Undefined + - + + + C*12:03:30 + HLA11101 + Undefined + - + + + C*12:03:31 + HLA11865 + Undefined + - + + + C*12:03:32 + HLA12773 + Undefined + - + + + C*12:03:33 + HLA12775 + Undefined + - + + + C*12:03:34:01 + HLA12873 + Undefined + - + + + C*12:03:34:02 + HLA13405 + Undefined + - + + + C*12:03:35 + HLA13101 + Undefined + - + + + C*12:03:36 + HLA13414 + Undefined + - + + + C*12:03:37 + HLA13531 + Undefined + - + + + C*12:03:38 + HLA15386 + Undefined + - + + + C*12:03:39 + HLA15900 + Undefined + - + + + C*12:03:40 + HLA15931 + Undefined + - + + + C*12:03:41 + HLA16273 + Undefined + - + + + C*12:03:42 + HLA16424 + Undefined + - + + + C*12:03:43 + HLA18051 + Undefined + - + + + C*12:03:44 + HLA18492 + Undefined + - + + + C*12:03:45 + HLA18500 + Undefined + - + + + C*12:03:46 + HLA18518 + Undefined + - + + + C*12:03:47 + HLA18527 + Undefined + - + + + C*12:03:48 + HLA18750 + Undefined + - + + + C*12:03:49 + HLA19019 + Undefined + - + + + C*12:03:50 + HLA19401 + Undefined + - + + + C*12:03:51 + HLA19232 + Undefined + - + + + C*12:03:52 + HLA20119 + Undefined + - + + + C*12:03:53 + HLA20971 + Undefined + - + + + C*12:03:54 + HLA20870 + Undefined + - + + + C*12:03:55 + HLA21395 + Undefined + - + + + C*12:03:56 + HLA22432 + Undefined + - + + + C*12:03:57 + HLA22997 + Undefined + - + + + C*12:03:58 + HLA23586 + Undefined + - + + + C*12:03:59 + HLA23301 + Undefined + - + + + C*12:03:60 + HLA24268 + Undefined + - + + + C*12:03:61 + HLA24172 + Undefined + - + + + C*12:03:62 + HLA26312 + Undefined + - + + + C*12:03:63 + HLA26772 + Undefined + - + + + C*12:03:64 + HLA27612 + Undefined + - + + + C*12:03:65 + HLA27809 + Undefined + - + + + C*12:03:66 + HLA28374 + Undefined + - + + + C*12:03:67 + HLA29791 + Undefined + - + + + C*12:03:68 + HLA30041 + Undefined + - + + + C*12:03:69 + HLA29968 + Undefined + - + + + C*12:03:70 + HLA29992 + Undefined + - + + + C*12:03:71 + HLA29972 + Undefined + - + + + C*12:03:72 + HLA29949 + Undefined + - + + + C*12:03:73 + HLA31166 + Undefined + - + + + C*12:03:74 + HLA31543 + Undefined + - + + + C*12:03:75 + HLA31669 + Undefined + - + + + C*12:03:76 + HLA31539 + Undefined + - + + + C*12:03:77 + HLA32011 + Undefined + - + + + C*12:03:78 + HLA33151 + Undefined + - + + + C*12:03:79 + HLA34473 + Undefined + - + + + C*12:03:80 + HLA34561 + Undefined + - + + + C*12:03:81 + HLA34853 + Undefined + - + + + C*12:03:82 + HLA36039 + Undefined + - + + + C*12:03:83 + HLA37065 + Undefined + - + + + C*12:04:01 + HLA00456 + Blank + - + + + C*12:04:02:01 + HLA00457 + Blank + - + + + C*12:04:02:02 + HLA24665 + Blank + - + + + C*12:04:03 + HLA33667 + Blank + - + + + C*12:05:01 + HLA00458 + Undefined + - + + + C*12:05:02 + HLA28507 + Undefined + - + + + C*12:06 + HLA00459 + Undefined + - + + + C*12:07 + HLA01138 + Undefined + - + + + C*12:08 + HLA01413 + Undefined + - + + + C*12:09 + HLA01705 + Undefined + - + + + C*12:10:01 + HLA01787 + Undefined + - + + + C*12:10:02 + HLA04679 + Undefined + - + + + C*12:10:03 + HLA33671 + Undefined + - + + + C*12:11 + HLA01799 + Undefined + - + + + C*12:12 + HLA01878 + Undefined + - + + + C*12:13:01:01 + HLA01954 + Undefined + - + + + C*12:13:01:02 + HLA19074 + Undefined + - + + + C*12:14:01 + HLA01935 + Cw7 + - + + + C*12:14:02 + HLA03619 + Cw7 + - + + + C*12:15 + HLA01969 + Undefined + - + + + C*12:16:01 + HLA02304 + Undefined + - + + + C*12:16:02 + HLA22672 + Undefined + - + + + C*12:17 + HLA02357 + Undefined + - + + + C*12:18:01 + HLA02527 + Undefined + - + + + C*12:18:02 + HLA07783 + Undefined + - + + + C*12:19 + HLA02605 + Undefined + - + + + C*12:20 + HLA02791 + Undefined + - + + + C*12:21 + HLA02842 + Undefined + - + + + C*12:22 + HLA03760 + Undefined + - + + + C*12:23 + HLA03988 + Undefined + - + + + C*12:24:01 + HLA04129 + Undefined + - + + + C*12:24:02 + HLA37844 + Undefined + - + + + C*12:25 + HLA04313 + Undefined + - + + + C*12:26 + HLA04316 + Undefined + - + + + C*12:27 + HLA04334 + Undefined + - + + + C*12:28 + HLA04336 + Undefined + - + + + C*12:29 + HLA04591 + Undefined + - + + + C*12:30 + HLA04592 + Undefined + - + + + C*12:31:01 + HLA04602 + Undefined + - + + + C*12:31:02 + HLA26257 + Undefined + - + + + C*12:32 + HLA04757 + Undefined + - + + + C*12:33 + HLA04766 + Undefined + - + + + C*12:34 + HLA04825 + Undefined + - + + + C*12:35 + HLA04834 + Undefined + - + + + C*12:36 + HLA05185 + Undefined + - + + + C*12:37 + HLA05187 + Undefined + - + + + C*12:38 + HLA05199 + Undefined + - + + + C*12:39N + HLA05203 + NotExpressed + Null + + + C*12:40 + HLA05204 + Undefined + - + + + C*12:41 + HLA05205 + Undefined + - + + + C*12:42Q + HLA05212 + Undefined + - + + + C*12:43 + HLA05214 + Undefined + - + + + C*12:44 + HLA05394 + Undefined + - + + + C*12:45 + HLA05570 + Undefined + - + + + C*12:46N + HLA05575 + NotExpressed + Null + + + C*12:47 + HLA05595 + Undefined + - + + + C*12:48 + HLA05608 + Undefined + - + + + C*12:49 + HLA05751 + Undefined + - + + + C*12:50 + HLA05837 + Undefined + - + + + C*12:51 + HLA06136 + Undefined + - + + + C*12:52 + HLA06384 + Undefined + - + + + C*12:53 + HLA06396 + Undefined + - + + + C*12:54 + HLA06414 + Undefined + - + + + C*12:55 + HLA06421 + Undefined + - + + + C*12:56 + HLA06426 + Undefined + - + + + C*12:57:01 + HLA06439 + Undefined + - + + + C*12:57:02 + HLA15941 + Undefined + - + + + C*12:58 + HLA06582 + Undefined + - + + + C*12:59 + HLA06722 + Undefined + - + + + C*12:60 + HLA06897 + Undefined + - + + + C*12:61 + HLA07055 + Undefined + - + + + C*12:62 + HLA07062 + Undefined + - + + + C*12:63 + HLA07076 + Undefined + - + + + C*12:64 + HLA07083 + Undefined + - + + + C*12:65 + HLA07231 + Undefined + - + + + C*12:66 + HLA07114 + Undefined + - + + + C*12:67 + HLA07223 + Undefined + - + + + C*12:68 + HLA07232 + Undefined + - + + + C*12:69 + HLA07490 + Undefined + - + + + C*12:70 + HLA07491 + Undefined + - + + + C*12:71 + HLA07741 + Undefined + - + + + C*12:72 + HLA07745 + Undefined + - + + + C*12:73 + HLA07782 + Undefined + - + + + C*12:74 + HLA07784 + Undefined + - + + + C*12:75 + HLA07786 + Undefined + - + + + C*12:76 + HLA07810 + Undefined + - + + + C*12:77 + HLA07852 + Undefined + - + + + C*12:78 + HLA07854 + Undefined + - + + + C*12:79 + HLA07856 + Undefined + - + + + C*12:80N + HLA08160 + NotExpressed + Null + + + C*12:81 + HLA08202 + Undefined + - + + + C*12:82 + HLA08218 + Undefined + - + + + C*12:83 + HLA08399 + Undefined + - + + + C*12:84N + HLA08421 + NotExpressed + Null + + + C*12:85:01 + HLA08426 + Undefined + - + + + C*12:85:02 + HLA34299 + Undefined + - + + + C*12:86 + HLA08744 + Undefined + - + + + C*12:87 + HLA08745 + Undefined + - + + + C*12:88 + HLA08746 + Undefined + - + + + C*12:89 + HLA08747 + Undefined + - + + + C*12:90 + HLA08748 + Undefined + - + + + C*12:91 + HLA08751 + Undefined + - + + + C*12:92 + HLA08893 + Undefined + - + + + C*12:93 + HLA09029 + Undefined + - + + + C*12:94 + HLA09086 + Undefined + - + + + C*12:95 + HLA09196 + Undefined + - + + + C*12:96 + HLA09299 + Undefined + - + + + C*12:97 + HLA09611 + Undefined + - + + + C*12:98 + HLA09613 + Undefined + - + + + C*12:99:01 + HLA09614 + Undefined + - + + + C*12:99:02 + HLA15802 + Undefined + - + + + C*12:100 + HLA10089 + Undefined + - + + + C*12:101 + HLA10090 + Undefined + - + + + C*12:102 + HLA10091 + Undefined + - + + + C*12:103 + HLA10092 + Undefined + - + + + C*12:104N + HLA10125 + NotExpressed + Null + + + C*12:105N + HLA10127 + NotExpressed + Null + + + C*12:106 + HLA10128 + Undefined + - + + + C*12:107 + HLA10132 + Undefined + - + + + C*12:108 + HLA10134 + Undefined + - + + + C*12:109 + HLA10136 + Undefined + - + + + C*12:110 + HLA10138 + Undefined + - + + + C*12:111 + HLA10139 + Undefined + - + + + C*12:112 + HLA10584 + Undefined + - + + + C*12:113 + HLA10585 + Undefined + - + + + C*12:114 + HLA10624 + Undefined + - + + + C*12:115 + HLA10625 + Undefined + - + + + C*12:116 + HLA10903 + Undefined + - + + + C*12:117 + HLA11099 + Undefined + - + + + C*12:118 + HLA11100 + Undefined + - + + + C*12:119 + HLA11102 + Undefined + - + + + C*12:120 + HLA11103 + Undefined + - + + + C*12:121 + HLA11259 + Undefined + - + + + C*12:122 + HLA11340 + Undefined + - + + + C*12:123 + HLA11466 + Undefined + - + + + C*12:124 + HLA11468 + Undefined + - + + + C*12:125 + HLA11490 + Undefined + - + + + C*12:126 + HLA11846 + Undefined + - + + + C*12:127 + HLA11861 + Undefined + - + + + C*12:128 + HLA11863 + Undefined + - + + + C*12:129 + HLA12043 + Undefined + - + + + C*12:130 + HLA12189 + Undefined + - + + + C*12:131 + HLA12190 + Undefined + - + + + C*12:132 + HLA12192 + Undefined + - + + + C*12:133 + HLA12334 + Undefined + - + + + C*12:134 + HLA12335 + Undefined + - + + + C*12:135 + HLA12429 + Undefined + - + + + C*12:136 + HLA12503 + Undefined + - + + + C*12:137 + HLA12507 + Undefined + - + + + C*12:138 + HLA12467 + Undefined + - + + + C*12:139Q + HLA12709 + Undefined + - + + + C*12:140:01 + HLA12715 + Undefined + - + + + C*12:140:02 + HLA19437 + Undefined + - + + + C*12:141 + HLA12735 + Undefined + - + + + C*12:142 + HLA12741 + Undefined + - + + + C*12:143 + HLA12837 + Undefined + - + + + C*12:144 + HLA12774 + Undefined + - + + + C*12:145 + HLA12776 + Undefined + - + + + C*12:146 + HLA12856 + Undefined + - + + + C*12:147 + HLA12866 + Undefined + - + + + C*12:148N + HLA12777 + NotExpressed + Null + + + C*12:149 + HLA13043 + Undefined + - + + + C*12:150 + HLA13105 + Undefined + - + + + C*12:151 + HLA13106 + Undefined + - + + + C*12:152 + HLA13107 + Undefined + - + + + C*12:153 + HLA13409 + Undefined + - + + + C*12:154 + HLA13412 + Undefined + - + + + C*12:155Q + HLA13416 + Undefined + - + + + C*12:156 + HLA13419 + Undefined + - + + + C*12:157 + HLA13565 + Undefined + - + + + C*12:158 + HLA13566 + Undefined + - + + + C*12:159 + HLA13567 + Undefined + - + + + C*12:160 + HLA13502 + Undefined + - + + + C*12:161 + HLA13700 + Undefined + - + + + C*12:162 + HLA13754 + Undefined + - + + + C*12:163 + HLA13872 + Undefined + - + + + C*12:164 + HLA13874 + Undefined + - + + + C*12:165 + HLA14028 + Undefined + - + + + C*12:166 + HLA13988 + Undefined + - + + + C*12:167 + HLA14117 + Undefined + - + + + C*12:168 + HLA14255 + Undefined + - + + + C*12:169 + HLA14256 + Undefined + - + + + C*12:170 + HLA14334 + Undefined + - + + + C*12:171 + HLA14231 + Undefined + - + + + C*12:172 + HLA14476 + Undefined + - + + + C*12:173 + HLA14751 + Undefined + - + + + C*12:174 + HLA14819 + Undefined + - + + + C*12:175 + HLA15051 + Undefined + - + + + C*12:176 + HLA15052 + Undefined + - + + + C*12:177 + HLA15134 + Undefined + - + + + C*12:178 + HLA15140 + Undefined + - + + + C*12:179 + HLA14953 + Undefined + - + + + C*12:180 + HLA14954 + Undefined + - + + + C*12:181 + HLA15168 + Undefined + - + + + C*12:182 + HLA15307 + Undefined + - + + + C*12:183 + HLA15308 + Undefined + - + + + C*12:184 + HLA15186 + Undefined + - + + + C*12:185 + HLA15191 + Undefined + - + + + C*12:186 + HLA15196 + Undefined + - + + + C*12:187 + HLA15421 + Undefined + - + + + C*12:188 + HLA15427 + Undefined + - + + + C*12:189 + HLA15659 + Undefined + - + + + C*12:190 + HLA15660 + Undefined + - + + + C*12:191 + HLA15661 + Undefined + - + + + C*12:192 + HLA15743 + Undefined + - + + + C*12:193 + HLA15624 + Undefined + - + + + C*12:194 + HLA15804 + Undefined + - + + + C*12:195:01 + HLA15889 + Undefined + - + + + C*12:195:02 + HLA16939 + Undefined + - + + + C*12:195:03 + HLA18064 + Undefined + - + + + C*12:196 + HLA15899 + Undefined + - + + + C*12:197 + HLA15906 + Undefined + - + + + C*12:198 + HLA15920 + Undefined + - + + + C*12:199 + HLA15932 + Undefined + - + + + C*12:200 + HLA15934 + Undefined + - + + + C*12:201 + HLA16173 + Undefined + - + + + C*12:202 + HLA16343 + Undefined + - + + + C*12:203 + HLA16528 + Undefined + - + + + C*12:204 + HLA16532 + Undefined + - + + + C*12:205 + HLA16533 + Undefined + - + + + C*12:206 + HLA16534 + Undefined + - + + + C*12:207 + HLA16767 + Undefined + - + + + C*12:208 + HLA16768 + Undefined + - + + + C*12:209 + HLA16736 + Undefined + - + + + C*12:210 + HLA16737 + Undefined + - + + + C*12:211 + HLA16738 + Undefined + - + + + C*12:212 + HLA16945 + Undefined + - + + + C*12:213 + HLA17099 + Undefined + - + + + C*12:214 + HLA17263 + Undefined + - + + + C*12:215 + HLA17619 + Undefined + - + + + C*12:216 + HLA17590 + Undefined + - + + + C*12:217 + HLA17872 + Undefined + - + + + C*12:218 + HLA17888 + Undefined + - + + + C*12:219N + HLA17890 + NotExpressed + Null + + + C*12:220 + HLA18073 + Undefined + - + + + C*12:221 + HLA18089 + Undefined + - + + + C*12:222 + HLA18156 + Undefined + - + + + C*12:223 + HLA18376 + Undefined + - + + + C*12:224 + HLA18378 + Undefined + - + + + C*12:225 + HLA18379 + Undefined + - + + + C*12:226 + HLA18391 + Undefined + - + + + C*12:227 + HLA18398 + Undefined + - + + + C*12:228 + HLA18399 + Undefined + - + + + C*12:229 + HLA18491 + Undefined + - + + + C*12:230 + HLA18529 + Undefined + - + + + C*12:231 + HLA18530 + Undefined + - + + + C*12:232N + HLA18535 + NotExpressed + Null + + + C*12:233 + HLA18526 + Undefined + - + + + C*12:234 + HLA18833 + Undefined + - + + + C*12:235 + HLA19087 + Undefined + - + + + C*12:236N + HLA19218 + NotExpressed + Null + + + C*12:237 + HLA19350 + Undefined + - + + + C*12:238 + HLA19197 + Undefined + - + + + C*12:239 + HLA19353 + Undefined + - + + + C*12:240 + HLA19755 + Undefined + - + + + C*12:241 + HLA19920 + Undefined + - + + + C*12:242 + HLA19940 + Undefined + - + + + C*12:243 + HLA19685 + Undefined + - + + + C*12:244 + HLA20000 + Undefined + - + + + C*12:245 + HLA19971 + Undefined + - + + + C*12:246 + HLA20224 + Undefined + - + + + C*12:247 + HLA19980 + Undefined + - + + + C*12:248 + HLA20026 + Undefined + - + + + C*12:249 + HLA20411 + Undefined + - + + + C*12:250 + HLA20039 + Undefined + - + + + C*12:251 + HLA20016 + Undefined + - + + + C*12:252 + HLA20189 + Undefined + - + + + C*12:253 + HLA20029 + Undefined + - + + + C*12:254 + HLA20181 + Undefined + - + + + C*12:255 + HLA20344 + Undefined + - + + + C*12:256 + HLA20180 + Undefined + - + + + C*12:257 + HLA20061 + Undefined + - + + + C*12:258 + HLA20611 + Undefined + - + + + C*12:259 + HLA21079 + Undefined + - + + + C*12:260:01 + HLA20622 + Undefined + - + + + C*12:260:02 + HLA27857 + Undefined + - + + + C*12:261 + HLA20589 + Undefined + - + + + C*12:262 + HLA20584 + Undefined + - + + + C*12:263 + HLA20740 + Undefined + - + + + C*12:264 + HLA20730 + Undefined + - + + + C*12:265 + HLA20562 + Undefined + - + + + C*12:266 + HLA20527 + Undefined + - + + + C*12:267 + HLA20944 + Undefined + - + + + C*12:268 + HLA21991 + Undefined + - + + + C*12:269 + HLA22251 + Undefined + - + + + C*12:270N + HLA22501 + NotExpressed + Null + + + C*12:271 + HLA22226 + Undefined + - + + + C*12:272 + HLA22525 + Undefined + - + + + C*12:273 + HLA22616 + Undefined + - + + + C*12:274:01N + HLA22207 + NotExpressed + Null + + + C*12:275 + HLA22446 + Undefined + - + + + C*12:276 + HLA22570 + Undefined + - + + + C*12:277 + HLA22391 + Undefined + - + + + C*12:278 + HLA22577 + Undefined + - + + + C*12:279 + HLA22371 + Undefined + - + + + C*12:280 + HLA22604 + Undefined + - + + + C*12:281 + HLA22451 + Undefined + - + + + C*12:282 + HLA22768 + Undefined + - + + + C*12:283 + HLA22805 + Undefined + - + + + C*12:284 + HLA23726 + Undefined + - + + + C*12:285 + HLA23371 + Undefined + - + + + C*12:286 + HLA23770 + Undefined + - + + + C*12:287 + HLA23153 + Undefined + - + + + C*12:288 + HLA23072 + Undefined + - + + + C*12:289 + HLA24235 + Undefined + - + + + C*12:290 + HLA23991 + Undefined + - + + + C*12:291 + HLA24205 + Undefined + - + + + C*12:292 + HLA23877 + Undefined + - + + + C*12:293 + HLA24074 + Undefined + - + + + C*12:294 + HLA24308 + Undefined + - + + + C*12:295N + HLA25377 + NotExpressed + Null + + + C*12:296 + HLA24458 + Undefined + - + + + C*12:297 + HLA25487 + Undefined + - + + + C*12:298 + HLA24699 + Undefined + - + + + C*12:299N + HLA25418 + NotExpressed + Null + + + C*12:300 + HLA25790 + Undefined + - + + + C*12:301 + HLA25744 + Undefined + - + + + C*12:302 + HLA26063 + Undefined + - + + + C*12:303 + HLA25853 + Undefined + - + + + C*12:304 + HLA26113 + Undefined + - + + + C*12:305 + HLA26282 + Undefined + - + + + C*12:306 + HLA26452 + Undefined + - + + + C*12:307 + HLA26590 + Undefined + - + + + C*12:308 + HLA27180 + Undefined + - + + + C*12:309 + HLA27686 + Undefined + - + + + C*12:310 + HLA27688 + Undefined + - + + + C*12:311N + HLA27698 + NotExpressed + Null + + + C*12:312 + HLA27823 + Undefined + - + + + C*12:313 + HLA27845 + Undefined + - + + + C*12:314 + HLA27847 + Undefined + - + + + C*12:315 + HLA27848 + Undefined + - + + + C*12:316 + HLA27853 + Undefined + - + + + C*12:317 + HLA27868 + Undefined + - + + + C*12:318 + HLA28132 + Undefined + - + + + C*12:319 + HLA28134 + Undefined + - + + + C*12:320 + HLA28168 + Undefined + - + + + C*12:321 + HLA28174 + Undefined + - + + + C*12:322 + HLA28091 + Undefined + - + + + C*12:323 + HLA28105 + Undefined + - + + + C*12:324N + HLA28109 + NotExpressed + Null + + + C*12:325 + HLA28376 + Undefined + - + + + C*12:326 + HLA28277 + Undefined + - + + + C*12:327N + HLA28284 + NotExpressed + Null + + + C*12:328 + HLA28509 + Undefined + - + + + C*12:329N + HLA26288 + NotExpressed + Null + + + C*12:330Q + HLA29292 + Undefined + - + + + C*12:331 + HLA29430 + Undefined + - + + + C*12:332 + HLA29550 + Undefined + - + + + C*12:333 + HLA29594 + Undefined + - + + + C*12:334 + HLA29811 + Undefined + - + + + C*12:335 + HLA30456 + Undefined + - + + + C*12:336 + HLA30208 + Undefined + - + + + C*12:337 + HLA30496 + Undefined + - + + + C*12:338 + HLA30133 + Undefined + - + + + C*12:339 + HLA30307 + Undefined + - + + + C*12:340 + HLA29969 + Undefined + - + + + C*12:341 + HLA30040 + Undefined + - + + + C*12:342Q + HLA30608 + Undefined + - + + + C*12:343N + HLA31213 + NotExpressed + Null + + + C*12:344 + HLA30981 + Undefined + - + + + C*12:345N + HLA30950 + NotExpressed + Null + + + C*12:346 + HLA31009 + Undefined + - + + + C*12:347 + HLA31480 + Undefined + - + + + C*12:348 + HLA31592 + Undefined + - + + + C*12:349 + HLA31566 + Undefined + - + + + C*12:350 + HLA32223 + Undefined + - + + + C*12:351Q + HLA32562 + Undefined + - + + + C*12:352 + HLA32960 + Undefined + - + + + C*12:353 + HLA33285 + Undefined + - + + + C*12:354 + HLA33242 + Undefined + - + + + C*12:355 + HLA33521 + Undefined + - + + + C*12:356 + HLA33501 + Undefined + - + + + C*12:357 + HLA33597 + Undefined + - + + + C*12:358 + HLA33545 + Undefined + - + + + C*12:359 + HLA34239 + Undefined + - + + + C*12:360 + HLA34234 + Undefined + - + + + C*12:361 + HLA34226 + Undefined + - + + 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C*15:02:01:52 + HLA32952 + Undefined + - + + + C*15:02:01:53 + HLA32867 + Undefined + - + + + C*15:02:01:54 + HLA34470 + Undefined + - + + + C*15:02:01:55 + HLA34484 + Undefined + - + + + C*15:02:01:56 + HLA35319 + Undefined + - + + + C*15:02:01:57 + HLA37042 + Undefined + - + + + C*15:02:01:58 + HLA37200 + Undefined + - + + + C*15:02:01:59 + HLA38444 + Undefined + - + + + C*15:02:01:60 + HLA38337 + Undefined + - + + + C*15:02:02:01 + HLA01081 + Undefined + - + + + C*15:02:02:02 + HLA18281 + Undefined + - + + + C*15:02:03 + HLA02424 + Undefined + - + + + C*15:02:04 + HLA03146 + Undefined + - + + + C*15:02:05 + HLA04624 + Undefined + - + + + C*15:02:06 + HLA05200 + Undefined + - + + + C*15:02:07 + HLA05893 + Undefined + - + + + C*15:02:08 + HLA07760 + Undefined + - + + + C*15:02:09 + HLA07789 + Undefined + - + + + C*15:02:10 + HLA07791 + Undefined + - + + + C*15:02:11 + HLA08757 + Undefined + - + + + C*15:02:12 + HLA08758 + Undefined + - + + + C*15:02:13 + HLA08759 + Undefined + - + + + C*15:02:14 + HLA08760 + Undefined + - + + + C*15:02:15 + HLA08763 + Undefined + - + + + C*15:02:16 + HLA09620 + Undefined + - + + + C*15:02:17 + HLA10148 + Undefined + - + + + C*15:02:18 + HLA10151 + Undefined + - + + + C*15:02:19 + HLA10156 + Undefined + - + + + C*15:02:20 + HLA12197 + Undefined + - + + + C*15:02:21 + HLA12907 + Undefined + - + + + C*15:02:22 + HLA13254 + Undefined + - + + + C*15:02:23 + HLA13255 + Undefined + - + + + C*15:02:24 + HLA13257 + Undefined + - + + + C*15:02:25 + HLA14598 + Undefined + - + + + C*15:02:26 + HLA14600 + Undefined + - + + + C*15:02:27 + HLA15419 + Undefined + - + + + C*15:02:28 + HLA15927 + Undefined + - + + + C*15:02:29 + HLA16847 + Undefined + - + + + C*15:02:30 + HLA17272 + Undefined + - + + + C*15:02:31 + HLA18232 + Undefined + - + + + C*15:02:32 + HLA18589 + Undefined + - + + + C*15:02:33:01 + HLA19608 + Undefined + - + + + C*15:02:33:02 + HLA23975 + Undefined + - + + + C*15:02:34 + HLA21344 + Undefined + - + + + C*15:02:35 + HLA21350 + Undefined + - + + + C*15:02:36 + HLA21374 + Undefined + - + + + C*15:02:37 + HLA21383 + Undefined + - + + + C*15:02:38 + HLA21336 + Undefined + - + + + C*15:02:39 + HLA21438 + Undefined + - + + + C*15:02:40 + HLA21453 + Undefined + - + + + C*15:02:41 + HLA22190 + Undefined + - + + + C*15:02:42 + HLA22647 + Undefined + - + + + C*15:02:43 + HLA24358 + Undefined + - + + + C*15:02:44 + HLA26187 + Undefined + - + + + C*15:02:45 + HLA26950 + Undefined + - + + + C*15:02:46 + HLA29572 + Undefined + - + + + C*15:02:47 + HLA29979 + Undefined + - + + + C*15:02:48 + HLA31027 + Undefined + - + + + C*15:02:49 + HLA31666 + Undefined + - + + + C*15:02:50 + HLA31951 + Undefined + - + + + C*15:02:51 + HLA32619 + Undefined + - + + + C*15:02:52 + HLA32701 + Undefined + - + + + C*15:02:53 + HLA33619 + Undefined + - + + + C*15:02:54 + HLA33709 + Undefined + - + + + C*15:02:55 + HLA34247 + Undefined + - + + + C*15:02:56 + HLA34213 + Undefined + - + + + C*15:02:57 + HLA34344 + Undefined + - + + + C*15:02:58 + HLA36067 + Undefined + - + + + C*15:02:59 + HLA36204 + Undefined + - + + + C*15:02:60 + HLA36656 + Undefined + - + + + C*15:02:61 + HLA36953 + Undefined + - + + + C*15:02:62 + HLA37177 + Undefined + - + + + C*15:02:63 + HLA37875 + Undefined + - + + + C*15:03 + HLA00468 + Undefined + - + + + C*15:04:01:01 + HLA00469 + Undefined + - + + + C*15:04:01:02 + HLA25128 + Undefined + - + + + C*15:04:01:03 + HLA24675 + Undefined + - + + + C*15:04:02 + HLA13115 + Undefined + - + + + C*15:04:03 + HLA16019 + Undefined + - + + + C*15:04:04 + HLA28369 + Undefined + - + + + C*15:04:05 + HLA28502 + Undefined + - + + + C*15:04:06 + HLA33182 + Undefined + - + + + C*15:05:01:01 + HLA00470 + Undefined + - + + + C*15:05:01:02 + HLA19610 + Undefined + - + + + C*15:05:01:03 + HLA22561 + Undefined + - + + + C*15:05:01:04 + HLA30480 + Undefined + - + + + C*15:05:02:01 + HLA00471 + Undefined + - + + + C*15:05:02:02 + HLA21168 + Undefined + - + + + C*15:05:02:03 + HLA25138 + Undefined + - + + + C*15:05:02:04 + HLA24739 + Undefined + - + + + C*15:05:02:05 + HLA25288 + Undefined + - + + + C*15:05:02:06 + HLA25145 + Undefined + - + + + C*15:05:02:07 + HLA24926 + Undefined + - + + + C*15:05:02:08 + HLA25821 + Undefined + - + + + C*15:05:02:09 + HLA30371 + Undefined + - + + + C*15:05:02:10 + HLA30369 + Undefined + - + + + C*15:05:02:11 + HLA33486 + Undefined + - + + + C*15:05:02:12 + HLA33315 + Undefined + - + + + C*15:05:02:13 + HLA33458 + Undefined + - + + + C*15:05:02:14 + HLA38272 + Undefined + - + + + C*15:05:03 + HLA01803 + Undefined + - + + + C*15:05:04 + HLA01909 + Undefined + - + + + C*15:05:05 + HLA05220 + Undefined + - + + + C*15:05:06 + HLA06416 + Undefined + - + + + C*15:05:07 + HLA08476 + Undefined + - + + + C*15:05:09 + HLA09627 + Undefined + - + + + C*15:05:10 + HLA10630 + Undefined + - + + + C*15:05:11 + HLA11261 + Undefined + - + + + C*15:05:12 + HLA15188 + Undefined + - + + + C*15:05:13 + HLA20071 + Undefined + - + + + C*15:05:14 + HLA20227 + Undefined + - + + + C*15:05:15 + HLA21104 + Undefined + - + + + C*15:05:16 + HLA23656 + Undefined + - + + + C*15:05:17 + HLA28292 + Undefined + - + + + C*15:05:18 + HLA30389 + Undefined + - + + + C*15:05:19 + HLA35815 + Undefined + - + + + C*15:05:20 + HLA36935 + Undefined + - + + + C*15:06:01:01 + HLA00472 + Undefined + - + + + C*15:06:01:02 + HLA35184 + Undefined + - + + + C*15:06:02 + HLA04779 + Undefined + - + + + C*15:06:03 + HLA05865 + Undefined + - + + + C*15:07:01:01 + HLA00473 + Cw3 + - + + + C*15:07:01:02 + HLA25222 + Cw3 + - + + + C*15:08:01 + HLA00474 + Undefined + - + + + C*15:08:02 + HLA21494 + Undefined + - + + + C*15:09:01:01 + HLA01124 + Undefined + - + + + C*15:09:01:02 + HLA23790 + Undefined + - + + + C*15:09:02 + HLA27116 + Undefined + - + + + C*15:10:01 + HLA01342 + Undefined + - + + + C*15:10:02 + HLA03108 + Undefined + - + + + C*15:10:03 + HLA10105 + Undefined + - + + + C*15:10:04 + HLA21353 + Undefined + - + + + C*15:11 + HLA01424 + Undefined + - + + + C*15:12 + HLA01884 + Undefined + - + + + C*15:13:01:01 + HLA02022 + Undefined + - + + + C*15:13:01:02 + HLA16841 + Undefined + - + + + C*15:13:02 + HLA29991 + Undefined + - + + + C*15:13:03 + HLA38706 + Undefined + - + + + C*15:15 + HLA02396 + Undefined + - + + + C*15:16:01 + HLA02404 + Undefined + - + + + C*15:16:02 + HLA33579 + Undefined + - + + + C*15:17 + HLA02438 + Undefined + - + + + C*15:18 + HLA02836 + Undefined + - + + + C*15:19 + HLA02837 + Undefined + - + + + C*15:20 + HLA02838 + Undefined + - + + + C*15:21 + HLA02928 + Cw3 + - + + + C*15:22 + HLA03813 + Undefined + - + + + C*15:23:01 + HLA04312 + Undefined + - + + + C*15:23:02 + HLA18394 + Undefined + - + + + C*15:24 + HLA04598 + Undefined + - + + + C*15:25 + HLA04579 + Undefined + - + + + C*15:26 + HLA04639 + Undefined + - + + + C*15:27 + HLA04693 + Undefined + - + + + C*15:28 + HLA04831 + Undefined + - + + + C*15:29 + HLA05113 + Undefined + - + + + C*15:30 + HLA05115 + Undefined + - + + + C*15:31 + HLA05158 + Undefined + - + + + C*15:32Q + HLA05160 + Undefined + - + + + C*15:33 + HLA05181 + Undefined + - + + + C*15:34 + HLA05198 + Undefined + - + + + C*15:35 + HLA05216 + Undefined + - + + + C*15:36 + HLA05558 + Undefined + - + + + C*15:37 + HLA05581 + Undefined + - + + + C*15:38 + HLA05600 + Undefined + - + + + C*15:39 + HLA05614 + Undefined + - + + + C*15:40 + HLA05615 + Undefined + - + + + C*15:41 + HLA05625 + Undefined + - + + + C*15:42 + HLA05750 + Undefined + - + + + C*15:43 + HLA05755 + Undefined + - + + + C*15:44:01 + HLA05854 + Undefined + - + + + C*15:44:02 + HLA15199 + Undefined + - + + + C*15:45 + HLA05879 + Undefined + - + + + C*15:46 + HLA06002 + Undefined + - + + + C*15:47 + HLA06073 + Undefined + - + + + C*15:48 + HLA06123 + Undefined + - + + + C*15:49 + HLA06434 + Undefined + - + + + C*15:50 + HLA06524 + Undefined + - + + + C*15:51 + HLA06725 + Undefined + - + + + C*15:52:01 + HLA07049 + Undefined + - + + + C*15:52:02 + HLA23430 + Undefined + - + + + C*15:53 + HLA07056 + Undefined + - + + + C*15:54 + HLA07067 + Undefined + - + + + C*15:55 + HLA07077 + Undefined + - + + + C*15:56 + HLA07139 + Undefined + - + + + C*15:57 + HLA07494 + Undefined + - + + + C*15:58 + HLA07787 + Undefined + - + + + C*15:59 + HLA07788 + Undefined + - + + + C*15:60 + HLA07790 + Undefined + - + + + C*15:61 + HLA08170 + Undefined + - + + + C*15:62 + HLA08534 + Undefined + - + + + C*15:63 + HLA08694 + Undefined + - + + + C*15:64 + HLA08761 + Undefined + - + + + C*15:65 + HLA08808 + Undefined + - + + + C*15:66 + HLA09037 + Undefined + - + + + C*15:67 + HLA09618 + Undefined + - + + + C*15:68 + HLA09619 + Undefined + - + + + C*15:69 + HLA09621 + Undefined + - + + + C*15:70 + HLA09622 + Undefined + - + + + C*15:71 + HLA09623 + Undefined + - + + + C*15:72 + HLA10095 + Undefined + - + + + C*15:73 + HLA10096 + Undefined + - + + + C*15:74 + HLA10097 + Undefined + - + + + C*15:75 + HLA10098 + Undefined + - + + + C*15:76 + HLA10099 + Undefined + - + + + C*15:77 + HLA10100 + Undefined + - + + + C*15:78:01 + HLA10149 + Undefined + - + + + C*15:78:02 + HLA15983 + Undefined + - + + + C*15:79 + HLA10152 + Undefined + - + + + C*15:80 + HLA10154 + Undefined + - + + + C*15:81 + HLA10155 + Undefined + - + + + C*15:82 + HLA10158 + Undefined + - + + + C*15:83 + HLA10440 + Undefined + - + + + C*15:84Q + HLA10629 + Undefined + - + + + C*15:85 + HLA10920 + Undefined + - + + + C*15:86 + HLA11112 + Undefined + - + + + C*15:87 + HLA11486 + Undefined + - + + + C*15:88 + HLA11574 + Undefined + - + + + C*15:89 + HLA11575 + Undefined + - + + + C*15:90 + HLA11576 + Undefined + - + + + C*15:91 + HLA11666 + Undefined + - + + + C*15:92N + HLA11667 + NotExpressed + Null + + + C*15:93 + HLA11869 + Undefined + - + + + C*15:94 + HLA12021 + Undefined + - + + + C*15:95N + HLA12022 + NotExpressed + Null + + + C*15:96Q + HLA12151 + Undefined + - + + + C*15:97 + HLA12183 + Undefined + - + + + C*15:98 + HLA12196 + Undefined + - + + + C*15:99 + HLA12198 + Undefined + - + + + C*15:100 + HLA12341 + Undefined + - + + + C*15:101 + HLA12342 + Undefined + - + + + C*15:102 + HLA12422 + Undefined + - + + + C*15:103 + HLA12572 + Undefined + - + + + C*15:104 + HLA12732 + Undefined + - + + + C*15:105Q + HLA12609 + Undefined + - + + + C*15:106 + HLA12781 + Undefined + - + + + C*15:107 + HLA13096 + Undefined + - + + + C*15:108 + HLA13114 + Undefined + - + + + C*15:109 + HLA13116 + Undefined + - + + + C*15:110 + HLA13252 + Undefined + - + + + C*15:111 + HLA13253 + Undefined + - + + + C*15:112 + HLA13256 + Undefined + - + + + C*15:113 + HLA13258 + Undefined + - + + + C*15:114 + HLA13569 + Undefined + - + + + C*15:115N + HLA13570 + NotExpressed + Null + + + C*15:116 + HLA13669 + Undefined + - + + + C*15:117 + HLA13755 + Undefined + - + + + C*15:118 + HLA14258 + Undefined + - + + + C*15:119 + HLA14336 + Undefined + - + + + C*15:120 + HLA14337 + Undefined + - + + + C*15:121 + HLA14539 + Undefined + - + + + C*15:122N + HLA14610 + NotExpressed + Null + + + C*15:123 + HLA14861 + Undefined + - + + + C*15:124 + HLA15058 + Undefined + - + + + C*15:125 + HLA15115 + Undefined + - + + + C*15:126 + HLA15117 + Undefined + - + + + C*15:127 + HLA15118 + Undefined + - + + + C*15:128 + HLA15127 + Undefined + - + + + C*15:129 + HLA15200 + Undefined + - + + + C*15:130 + HLA15633 + Undefined + - + + + C*15:131 + HLA15664 + Undefined + - + + + C*15:132 + HLA15795 + Undefined + - + + + C*15:133 + HLA15937 + Undefined + - + + + C*15:134 + HLA16042 + Undefined + - + + + C*15:135 + HLA16539 + Undefined + - + + + C*15:136 + HLA16540 + Undefined + - + + + C*15:137 + HLA16541 + Undefined + - + + + C*15:138 + HLA16762 + Undefined + - + + + C*15:139 + HLA17017 + Undefined + - + + + C*15:140 + HLA17018 + Undefined + - + + + C*15:141 + HLA17019 + Undefined + - + + + C*15:142 + HLA17020 + Undefined + - + + + C*15:143 + HLA17062 + Undefined + - + + + C*15:144 + HLA17442 + Undefined + - + + + C*15:145N + HLA17513 + NotExpressed + Null + + + C*15:146 + HLA17626 + Undefined + - + + + C*15:147 + HLA17893 + Undefined + - + + + C*15:148 + HLA17894 + Undefined + - + + + C*15:149 + HLA17895 + Undefined + - + + + C*15:150 + HLA17896 + Undefined + - + + + C*15:151 + HLA18094 + Undefined + - + + + C*15:152:01 + HLA18101 + Undefined + - + + + C*15:152:02 + HLA18377 + Undefined + - + + + C*15:152:03 + HLA09036 + Undefined + - + + + C*15:153 + HLA18384 + Undefined + - + + + C*15:154 + HLA18403 + Undefined + - + + + C*15:155 + HLA18498 + Undefined + - + + + C*15:156N + HLA19025 + NotExpressed + Null + + + C*15:157 + HLA19179 + Undefined + - + + + C*15:158 + HLA19424 + Undefined + - + + + C*15:159 + HLA19588 + Undefined + - + + + C*15:160N + HLA19316 + NotExpressed + Null + + + C*15:161 + HLA19717 + Undefined + - + + + C*15:162 + HLA20362 + Undefined + - + + + C*15:163 + HLA20311 + Undefined + - + + + C*15:164N + HLA20479 + NotExpressed + Null + + + C*15:165 + HLA20430 + Undefined + - + + + C*15:166 + HLA20487 + Undefined + - + + + C*15:167 + HLA20162 + Undefined + - + + + C*15:168 + HLA20660 + Undefined + - + + + C*15:169 + HLA20783 + Undefined + - + + + C*15:170 + HLA21403 + Undefined + - + + + C*15:171 + HLA21274 + Undefined + - + + + C*15:172 + HLA21321 + Undefined + - + + + C*15:173 + HLA21457 + Undefined + - + + + C*15:174 + HLA21585 + Undefined + - + + + C*15:175 + HLA21309 + Undefined + - + + + C*15:176 + HLA21481 + Undefined + - + + + C*15:177N + HLA21517 + NotExpressed + Null + + + C*15:178 + HLA21557 + Undefined + - + + + C*15:179 + HLA21225 + Undefined + - + + + C*15:180 + HLA21358 + Undefined + - + + + C*15:181 + HLA21230 + Undefined + - + + + C*15:182 + HLA21261 + Undefined + - + + + C*15:183 + HLA21280 + Undefined + - + + + C*15:184 + HLA22046 + Undefined + - + + + C*15:185N + HLA22056 + NotExpressed + Null + + + C*15:186 + HLA22009 + Undefined + - + + + C*15:187 + HLA22107 + Undefined + - + + + C*15:188N + HLA22443 + NotExpressed + Null + + + C*15:189N + HLA22437 + NotExpressed + Null + + + C*15:190 + HLA22470 + Undefined + - + + + C*15:191 + HLA22608 + Undefined + - + + + C*15:192 + HLA22533 + Undefined + - + + + C*15:193 + HLA22510 + Undefined + - + + + C*15:194 + HLA22775 + Undefined + - + + + C*15:195 + HLA22711 + Undefined + - + + + C*15:196 + HLA22898 + Undefined + - + + + C*15:197 + HLA23373 + Undefined + - + + + C*15:198 + HLA23687 + Undefined + - + + + C*15:199 + HLA23024 + Undefined + - + + + C*15:200 + HLA23496 + Undefined + - + + + C*15:201 + HLA24077 + Undefined + - + + + C*15:202 + HLA23898 + Undefined + - + + + C*15:203 + HLA24041 + Undefined + - + + + C*15:204 + HLA24631 + Undefined + - + + + C*15:205 + HLA25631 + Undefined + - + + + C*15:206 + HLA25791 + Undefined + - + + + C*15:207 + HLA26152 + Undefined + - + + + C*15:208 + HLA26242 + Undefined + - + + + C*15:209 + HLA26832 + Undefined + - + + + C*15:210 + HLA26822 + Undefined + - + + + C*15:211 + HLA27164 + Undefined + - + + + C*15:212 + HLA27165 + Undefined + - + + + C*15:213N + HLA27170 + NotExpressed + Null + + + C*15:214 + HLA27175 + Undefined + - + + + C*15:215 + HLA27325 + Undefined + - + + + C*15:216N + HLA27488 + NotExpressed + Null + + + C*15:217 + HLA27326 + Undefined + - + + + C*15:218 + HLA27784 + Undefined + - + + + C*15:219 + HLA27901 + Undefined + - + + + C*15:220 + HLA28177 + Undefined + - + + + C*15:221 + HLA28101 + Undefined + - + + + C*15:222 + HLA28388 + Undefined + - + + + C*15:223 + HLA28421 + Undefined + - + + + C*15:224 + HLA28451 + Undefined + - + + + C*15:225 + HLA28508 + Undefined + - + + + C*15:226 + HLA28513 + Undefined + - + + + C*15:227 + HLA29004 + Undefined + - + + + C*15:228 + HLA29022 + Undefined + - + + + C*15:229 + HLA29197 + Undefined + - + + + C*15:230 + HLA29216 + Undefined + - + + + C*15:231 + HLA30282 + Undefined + - + + + C*15:232 + HLA29984 + Undefined + - + + + C*15:233 + HLA29994 + Undefined + - + + + C*15:234 + HLA31142 + Undefined + - + + + C*15:235Q + HLA30996 + Undefined + - + + + C*15:236 + HLA31273 + Undefined + - + + + C*15:237 + HLA31291 + Undefined + - + + + C*15:238N + HLA31661 + NotExpressed + Null + + + C*15:239 + HLA31632 + Undefined + - + + + C*15:240 + HLA31769 + Undefined + - + + + C*15:241 + HLA31569 + Undefined + - + + + C*15:242 + HLA32096 + Undefined + - + + + C*15:243Q + HLA32279 + Undefined + - + + + C*15:244 + HLA32602 + Undefined + - + + + C*15:245 + HLA32676 + Undefined + - + + + C*15:246 + HLA32689 + Undefined + - + + + C*15:247N + HLA33565 + NotExpressed + Null + + + C*15:248 + HLA33520 + Undefined + - + + + C*15:249 + HLA34235 + Undefined + - + + + C*15:250 + HLA34415 + Undefined + - + + + C*15:251 + HLA34851 + Undefined + - + + + C*15:252 + HLA35932 + Undefined + - + + + C*15:253Q + HLA35640 + Undefined + - + + + C*15:254 + HLA36156 + Undefined + - + + + C*15:255 + HLA36850 + Undefined + - + + + C*15:256N + HLA37052 + NotExpressed + Null + + + C*15:257 + HLA37094 + Undefined + - + + + C*15:258 + HLA37459 + Undefined + - + + + C*15:259 + HLA37689 + Undefined + - + + + C*15:260 + HLA37848 + Undefined + - + + + C*15:261 + HLA38569 + Undefined + - + + + C*15:262 + HLA38708 + Undefined + - + + + C*16:01:01:01 + HLA00475 + Undefined + - + + + C*16:01:01:02 + HLA13972 + Undefined + - + + + C*16:01:01:03 + HLA16727 + Undefined + - + + + C*16:01:01:04 + HLA17052 + Undefined + - + + + C*16:01:01:05 + HLA19020 + Undefined + - + + + C*16:01:01:06 + HLA20090 + Undefined + - + + + C*16:01:01:07 + HLA24663 + Undefined + - + + + C*16:01:01:08 + HLA25323 + Undefined + - + + + C*16:01:01:09 + HLA24929 + Undefined + - + + + C*16:01:01:10 + HLA24863 + Undefined + - + + + C*16:01:01:11 + HLA24946 + Undefined + - + + + C*16:01:01:12 + HLA25264 + Undefined + - + + + C*16:01:01:13 + HLA25259 + Undefined + - + + + C*16:01:01:14 + HLA26162 + Undefined + - + + + C*16:01:01:15 + HLA26123 + Undefined + - + + + C*16:01:01:16 + HLA27132 + Undefined + - + + + C*16:01:01:17 + HLA27269 + Undefined + - + + + C*16:01:01:18 + HLA27833 + Undefined + - + + + C*16:01:01:19 + HLA27854 + Undefined + - + + + C*16:01:01:20 + HLA28591 + Undefined + - + + + C*16:01:01:21 + HLA29491 + Undefined + - + + + C*16:01:01:22 + HLA30353 + Undefined + - + + + C*16:01:01:23 + HLA29902 + Undefined + - + + + C*16:01:01:24 + HLA32081 + Undefined + - + + + C*16:01:01:25 + HLA32058 + Undefined + - + + + C*16:01:01:26 + HLA31946 + Undefined + - + + + C*16:01:01:27 + HLA32082 + Undefined + - + + + C*16:01:01:28 + HLA32948 + Undefined + - + + + C*16:01:01:29 + HLA32890 + Undefined + - + + + C*16:01:01:30 + HLA33023 + Undefined + - + + + C*16:01:01:31 + HLA32840 + Undefined + - + + + C*16:01:01:32 + HLA32838 + Undefined + - + + + C*16:01:01:33 + HLA32761 + Undefined + - + + + C*16:01:01:34 + HLA32951 + Undefined + - + + + C*16:01:01:35 + HLA33119 + Undefined + - + + + C*16:01:01:36 + HLA33618 + Undefined + - + + + C*16:01:01:37 + HLA33641 + Undefined + - + + + C*16:01:01:38 + HLA35199 + Undefined + - + + + C*16:01:01:39 + HLA37465 + Undefined + - + + + C*16:01:01:40 + HLA38421 + Undefined + - + + + C*16:01:02 + HLA02041 + Undefined + - + + + C*16:01:03 + HLA02868 + Undefined + - + + + C*16:01:04 + HLA04627 + Undefined + - + + + C*16:01:05 + HLA05596 + Undefined + - + + + C*16:01:06 + HLA06303 + Undefined + - + + + C*16:01:07 + HLA07136 + Undefined + - + + + C*16:01:08 + HLA08117 + Undefined + - + + + C*16:01:09 + HLA08161 + Undefined + - + + + C*16:01:10 + HLA08204 + Undefined + - + + + C*16:01:11 + HLA08743 + Undefined + - + + + C*16:01:12 + HLA09027 + Undefined + - + + + C*16:01:13 + HLA09028 + Undefined + - + + + C*16:01:14 + HLA10086 + Undefined + - + + + C*16:01:15 + HLA10087 + Undefined + - + + + C*16:01:16 + HLA11104 + Undefined + - + + + C*16:01:17 + HLA11339 + Undefined + - + + + C*16:01:18 + HLA11467 + Undefined + - + + + C*16:01:19 + HLA12193 + Undefined + - + + + C*16:01:20 + HLA14607 + Undefined + - + + + C*16:01:21 + HLA15133 + Undefined + - + + + C*16:01:22 + HLA15187 + Undefined + - + + + C*16:01:23 + HLA18523 + Undefined + - + + + C*16:01:24 + HLA18743 + Undefined + - + + + C*16:01:25 + HLA19446 + Undefined + - + + + C*16:01:26 + HLA19569 + Undefined + - + + + C*16:01:27 + HLA19435 + Undefined + - + + + C*16:01:28 + HLA19872 + Undefined + - + + + C*16:01:29 + HLA20019 + Undefined + - + + + C*16:01:30 + HLA20135 + Undefined + - + + + C*16:01:31 + HLA20020 + Undefined + - + + + C*16:01:32 + HLA21102 + Undefined + - + + + C*16:01:33 + HLA23217 + Undefined + - + + + C*16:01:34 + HLA23573 + Undefined + - + + + C*16:01:35 + HLA24109 + Undefined + - + + + C*16:01:36 + HLA25260 + Undefined + - + + + C*16:01:37 + HLA27144 + Undefined + - + + + C*16:01:38 + HLA28136 + Undefined + - + + + C*16:01:39 + HLA28100 + Undefined + - + + + C*16:01:40 + HLA29158 + Undefined + - + + + C*16:01:41 + HLA30212 + Undefined + - + + + C*16:01:42 + HLA33652 + Undefined + - + + + C*16:01:43 + HLA35397 + Undefined + - + + + C*16:01:44 + HLA36963 + Undefined + - + + + C*16:01:45 + HLA38271 + Undefined + - + + + C*16:01:46 + HLA38409 + Undefined + - + + + C*16:01:47 + HLA38687 + Undefined + - + + + C*16:02:01:01 + HLA00476 + Undefined + - + + + C*16:02:01:02 + HLA25140 + Undefined + - + + + C*16:02:01:03 + HLA26317 + Undefined + - + + + C*16:02:01:04 + HLA29591 + Undefined + - + + + C*16:02:01:05 + HLA33147 + Undefined + - + + + C*16:02:01:06 + HLA37882 + Undefined + - + + + C*16:02:02 + HLA04604 + Undefined + - + + + C*16:02:03 + HLA04829 + Undefined + - + + + C*16:02:04 + HLA04839 + Undefined + - + + + C*16:02:05 + HLA05624 + Undefined + - + + + C*16:02:06 + HLA06047 + Undefined + - + + + C*16:02:07 + HLA06438 + Undefined + - + + + C*16:02:08 + HLA07048 + Undefined + - + + + C*16:02:09 + HLA07234 + Undefined + - + + + C*16:02:10 + HLA10084 + Undefined + - + + + C*16:02:11 + HLA10085 + Undefined + - + + + C*16:02:12 + HLA11257 + Undefined + - + + + C*16:02:13 + HLA12506 + Undefined + - + + + C*16:02:14 + HLA18048 + Undefined + - + + + C*16:02:15 + HLA18471 + Undefined + - + + + C*16:02:16 + HLA19114 + Undefined + - + + + C*16:02:17 + HLA22511 + Undefined + - + + + C*16:02:18 + HLA28135 + Undefined + - + + + C*16:02:19 + HLA30426 + Undefined + - + + + C*16:02:20 + HLA31588 + Undefined + - + + + C*16:04:01:01 + HLA00478 + Undefined + - + + + C*16:04:01:02 + HLA16842 + Undefined + - + + + C*16:04:01:03 + HLA25441 + Undefined + - + + + C*16:04:03 + HLA12719 + Undefined + - + + + C*16:04:04 + HLA15980 + Undefined + - + + + C*16:04:05 + HLA17013 + Undefined + - + + + C*16:06 + HLA01708 + Undefined + - + + + C*16:07:01 + HLA02242 + Undefined + - + + + C*16:07:02 + HLA06276 + Undefined + - + + + C*16:08 + HLA02303 + Undefined + - + + + C*16:09 + HLA02686 + Undefined + - + + + C*16:10 + HLA03115 + Undefined + - + + + C*16:11 + HLA03238 + Undefined + - + + + C*16:12 + HLA03425 + Undefined + - + + + C*16:13 + HLA03726 + Undefined + - + + + C*16:14 + HLA03738 + Undefined + - + + + C*16:15:02 + HLA05871 + Undefined + - + + + C*16:16Q + HLA04333 + Undefined + - + + + C*16:17 + HLA04346 + Undefined + - + + + C*16:18 + HLA04599 + Undefined + - + + + C*16:19 + HLA04632 + Undefined + - + + + C*16:20 + HLA04698 + Undefined + - + + + C*16:21 + HLA04767 + Undefined 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C*16:68 + HLA11097 + Undefined + - + + + C*16:69 + HLA11098 + Undefined + - + + + C*16:70 + HLA11111 + Undefined + - + + + C*16:71 + HLA11862 + Undefined + - + + + C*16:72 + HLA11864 + Undefined + - + + + C*16:73 + HLA11973 + Undefined + - + + + C*16:74 + HLA12044 + Undefined + - + + + C*16:75 + HLA12144 + Undefined + - + + + C*16:76 + HLA12191 + Undefined + - + + + C*16:77N + HLA12608 + NotExpressed + Null + + + C*16:78 + HLA12673 + Undefined + - + + + C*16:79 + HLA12772 + Undefined + - + + + C*16:80 + HLA13030 + Undefined + - + + + C*16:81 + HLA13102 + Undefined + - + + + C*16:82 + HLA13103 + Undefined + - + + + C*16:83 + HLA13104 + Undefined + - + + + C*16:84 + HLA13417 + Undefined + - + + + C*16:85 + HLA13486 + Undefined + - + + + C*16:86 + HLA13743 + Undefined + - + + + C*16:87 + HLA14027 + Undefined + - + + + C*16:88 + HLA14254 + Undefined + - + + + C*16:89N + HLA14257 + NotExpressed + Null + + + C*16:90 + HLA14454 + Undefined + - + + + C*16:91 + HLA14531 + Undefined + - + + + C*16:92 + HLA14482 + Undefined + - + + + C*16:93 + HLA14609 + Undefined + - + + + C*16:94 + HLA15050 + Undefined + - + + + C*16:95 + HLA15053 + Undefined + - + + + C*16:96 + HLA15139 + Undefined + - + + + C*16:97 + HLA14959 + Undefined + - + + + C*16:98:01 + HLA15306 + Undefined + - + + + C*16:98:02 + HLA38644 + Undefined + - + + + C*16:99 + HLA15663 + Undefined + - + + + C*16:100 + HLA15615 + Undefined + - + + + C*16:101 + HLA15926 + Undefined + - + + + C*16:102 + HLA16182 + Undefined + - + + + C*16:103 + HLA16529 + Undefined + - + + + C*16:104 + HLA16530 + Undefined + - + + + C*16:105 + HLA16531 + Undefined + - + + + C*16:106 + HLA16739 + Undefined + - + + + C*16:107 + HLA16943 + Undefined + - + + + C*16:108 + HLA16944 + Undefined + - + + + C*16:109 + HLA17014 + Undefined + - + + + C*16:110 + HLA17015 + Undefined + - + + + C*16:111 + HLA17269 + Undefined + - + + + C*16:112 + HLA17422 + Undefined + - + + + C*16:113 + HLA17510 + Undefined + - + + + C*16:114 + HLA17653 + Undefined + - + 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HLA20217 + Undefined + - + + + C*16:139 + HLA20113 + Undefined + - + + + C*16:140 + HLA20033 + Undefined + - + + + C*16:141 + HLA20042 + Undefined + - + + + C*16:142 + HLA20874 + Undefined + - + + + C*16:143 + HLA20822 + Undefined + - + + + C*16:144 + HLA21067 + Undefined + - + + + C*16:145 + HLA20978 + Undefined + - + + + C*16:146 + HLA21469 + Undefined + - + + + C*16:147 + HLA21973 + Undefined + - + + + C*16:148 + HLA22035 + Undefined + - + + + C*16:149 + HLA22277 + Undefined + - + + + C*16:150 + HLA22260 + Undefined + - + + + C*16:151 + HLA22702 + Undefined + - + + + C*16:152 + HLA22703 + Undefined + - + + + C*16:153 + HLA22894 + Undefined + - + + + C*16:154 + HLA23370 + Undefined + - + + + C*16:155 + HLA23058 + Undefined + - + + + C*16:156 + HLA23267 + Undefined + - + + + C*16:157 + HLA23933 + Undefined + - + + + C*16:158 + HLA23900 + Undefined + - + + + C*16:159 + HLA24146 + Undefined + - + + + C*16:160 + HLA24261 + Undefined + - + + + C*16:161 + HLA24017 + Undefined + - + + + C*16:162 + HLA23960 + Undefined + - + + + C*16:163 + HLA24696 + Undefined + - + + + C*16:164 + HLA25982 + Undefined + - + + + C*16:165 + HLA26365 + Undefined + - + + + C*16:166 + HLA26949 + Undefined + - + + + C*16:167 + HLA27684 + Undefined + - + + + C*16:168 + HLA27770 + Undefined + - + + + C*16:169 + HLA27860 + Undefined + - + + + C*16:170 + HLA28153 + Undefined + - + + + C*16:171 + HLA28171 + Undefined + - + + + C*16:172 + HLA28103 + Undefined + - + + + C*16:173 + HLA28242 + Undefined + - + + + C*16:174Q + HLA28618 + Undefined + - + + + C*16:175 + HLA28882 + Undefined + - + + + C*16:176 + HLA29017 + Undefined + - + + + C*16:177 + HLA29562 + Undefined + - + + + C*16:178 + HLA29546 + Undefined + - + + + C*16:179 + HLA29450 + Undefined + - + + + C*16:180 + HLA30479 + Undefined + - + + + C*16:181 + HLA29904 + Undefined + - + + + C*16:182 + HLA29958 + Undefined + - + + + C*16:183 + HLA30550 + Undefined + - + + + C*16:184 + HLA30789 + Undefined + - + + + C*16:185 + HLA30847 + Undefined + - + + + C*16:186N + HLA31835 + NotExpressed + Null + + + C*16:187 + HLA31464 + Undefined + - + + + C*16:188 + HLA32780 + Undefined + - + + + C*16:189 + HLA33596 + Undefined + - + + + C*16:190 + HLA33642 + Undefined + - + + + C*16:191 + HLA33515 + Undefined + - + + + C*16:192 + HLA33677 + Undefined + - + + + C*16:193 + HLA33797 + Undefined + - + + + C*16:194 + HLA34246 + Undefined + - + + + C*16:195N + HLA34121 + NotExpressed + Null + + + C*16:196 + HLA34396 + Undefined + - + + + C*16:197 + HLA34341 + Undefined + - + + + C*16:198 + HLA34960 + Undefined + - + + + C*16:200 + HLA34968 + Undefined + - + + + C*16:201 + HLA04321 + Undefined + - + + + C*16:202 + HLA36160 + Undefined + - + + + C*16:203 + HLA36347 + Undefined + - + + + C*16:204 + HLA36705 + Undefined + - + + + C*16:205 + HLA37060 + Undefined + - + + + C*16:206N + HLA37297 + NotExpressed + Null + + + C*16:207 + HLA37388 + Undefined + - + + + C*16:208 + HLA37553 + Undefined + - + + + C*16:209 + HLA37590 + Undefined + - + + + C*16:210 + HLA37920 + Undefined + - + + + C*16:211 + HLA37745 + Undefined + - + + + C*16:212 + HLA38009 + Undefined + - + + + C*16:213 + HLA38293 + Undefined + - + + + C*16:214 + HLA38732 + Undefined + - + + + C*16:215 + HLA38702 + Undefined + - + + + C*17:01:01:01 + HLA00481 + Cw7/blank + - + + + C*17:01:01:02 + HLA04311 + Cw7/blank + - + + + C*17:01:01:03 + HLA10025 + Cw7/blank + - + + + C*17:01:01:04 + HLA14089 + Cw7/blank + - + + + C*17:01:01:05 + HLA14101 + Cw7/blank + - + + + C*17:01:01:06 + HLA22624 + Cw7/blank + - + + + C*17:01:01:07 + HLA24923 + Cw7/blank + - + + + C*17:01:01:08 + HLA25550 + Cw7/blank + - + + + C*17:01:01:09 + HLA24461 + Cw7/blank + - + + + C*17:01:01:10 + HLA26962 + Cw7/blank + - + + + C*17:01:01:11 + HLA27557 + Cw7/blank + - + + + C*17:01:01:12 + HLA27872 + Cw7/blank + - + + + C*17:01:01:13 + HLA28252 + Cw7/blank + - + + + C*17:01:01:14 + HLA28261 + Cw7/blank + - + + + C*17:01:01:15 + HLA29235 + Cw7/blank + - + + + C*17:01:01:16Q + HLA30042 + Undefined + - + 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DQ2 + + + DQB1*02:02:01:08 + HLA31108 + DQ2 + DQ2 + + + DQB1*02:02:01:09 + HLA32131 + DQ2 + DQ2 + + + DQB1*02:02:01:10 + HLA33646 + DQ2 + DQ2 + + + DQB1*02:02:01:11 + HLA33783 + DQ2 + DQ2 + + + DQB1*02:02:01:12 + HLA33735 + DQ2 + DQ2 + + + DQB1*02:02:01:13 + HLA34437 + DQ2 + DQ2 + + + DQB1*02:02:01:14 + HLA35580 + DQ2 + DQ2 + + + DQB1*02:02:01:15 + HLA36552 + DQ2 + DQ2 + + + DQB1*02:02:01:16 + HLA36590 + DQ2 + DQ2 + + + DQB1*02:02:01:17 + HLA36345 + DQ2 + DQ2 + + + DQB1*02:02:01:18 + HLA37996 + DQ2 + DQ2 + + + DQB1*02:02:01:19 + HLA38001 + DQ2 + DQ2 + + + DQB1*02:02:02 + HLA09092 + DQ2 + DQ2 + + + DQB1*02:02:03 + HLA15617 + DQ2 + DQ2 + + + DQB1*02:02:04 + HLA16141 + DQ2 + DQ2 + + + DQB1*02:02:05 + HLA17977 + DQ2 + DQ2 + + + DQB1*02:02:06:01 + HLA20231 + DQ2 + DQ2 + + + DQB1*02:02:06:02 + HLA26539 + DQ2 + DQ2 + + + DQB1*02:02:07 + HLA21041 + DQ2 + DQ2 + + + DQB1*02:02:08 + HLA20594 + DQ2 + DQ2 + + + DQB1*02:02:09 + HLA20540 + DQ2 + DQ2 + + + DQB1*02:02:10 + HLA26014 + DQ2 + DQ2 + + + DQB1*02:02:11 + HLA26110 + DQ2 + DQ2 + + + DQB1*02:02:12 + HLA26163 + DQ2 + DQ2 + + + DQB1*02:02:13 + HLA28233 + DQ2 + DQ2 + + + DQB1*02:02:14 + HLA29290 + DQ2 + DQ2 + + + DQB1*02:02:15 + HLA09252 + DQ2 + DQ2 + + + DQB1*02:02:16 + HLA32170 + DQ2 + DQ2 + + + DQB1*02:02:17 + HLA10278 + DQ2 + DQ2 + + + DQB1*02:02:18 + HLA34416 + DQ2 + DQ2 + + + DQB1*02:02:19 + HLA36126 + DQ2 + DQ2 + + + DQB1*02:02:20 + HLA36382 + DQ2 + DQ2 + + + DQB1*02:02:21 + HLA36411 + DQ2 + DQ2 + + + DQB1*02:02:22 + HLA36582 + DQ2 + DQ2 + + + DQB1*02:02:23 + HLA36832 + DQ2 + DQ2 + + + DQB1*02:02:24 + HLA37377 + DQ2 + DQ2 + + + DQB1*02:03:02 + HLA21020 + DQ2 + DQ2 + + + DQB1*02:03 + HLA00624 + DQ2 + DQ2 + + + DQB1*02:04 + HLA02136 + DQ2 + - + + + DQB1*02:05 + HLA02890 + DQ2 + - + + + DQB1*02:06 + HLA06141 + Undefined + - + + + DQB1*02:07:01 + HLA08083 + Undefined + - + + + DQB1*02:07:02 + HLA11673 + Undefined + - + + + DQB1*02:08 + HLA08916 + Undefined + - + + + DQB1*02:09 + HLA08918 + Undefined + - + + + DQB1*02:10 + HLA08924 + Undefined + - + + + DQB1*02:11 + HLA09091 + Undefined + - + + + DQB1*02:12 + HLA09127 + Undefined + - + + + DQB1*02:13 + HLA09243 + Undefined + - + + + DQB1*02:14:01:01 + HLA09245 + Undefined + - + + + DQB1*02:14:01:02 + HLA28470 + Undefined + - + + + DQB1*02:14:02 + HLA12353 + Undefined + - + + + DQB1*02:15 + HLA09246 + Undefined + - + + + DQB1*02:16 + HLA09248 + Undefined + - + + + DQB1*02:17 + HLA09249 + Undefined + - + + + DQB1*02:18N + HLA09250 + NotExpressed + Null + + + DQB1*02:19 + HLA09251 + Undefined + - + + + DQB1*02:20:01:01N + HLA09253 + NotExpressed + Null + + + DQB1*02:20:01:02N + HLA36755 + NotExpressed + Null + + + DQB1*02:21 + HLA09255 + Undefined + - + + + DQB1*02:22 + HLA09256 + Undefined + - + + + DQB1*02:23 + HLA09257 + Undefined + - + + + DQB1*02:24 + HLA09258 + Undefined + - + + + DQB1*02:25 + HLA09259 + Undefined + - + + + DQB1*02:26 + HLA09260 + Undefined + - + + + DQB1*02:27 + HLA09344 + Undefined + - + + + DQB1*02:28 + HLA09355 + Undefined + - + + + DQB1*02:29 + HLA09357 + Undefined + - + + + DQB1*02:30 + HLA09641 + Undefined + - + + + DQB1*02:31 + HLA09642 + Undefined + - + + + DQB1*02:32 + HLA09730 + Undefined + - + + + DQB1*02:33 + HLA09742 + Undefined + - + + + DQB1*02:34 + HLA10279 + Undefined + - + + + DQB1*02:35 + HLA10543 + Undefined + - + + + DQB1*02:36 + HLA11126 + Undefined + - + + + DQB1*02:37 + HLA11133 + Undefined + - + + + DQB1*02:38 + HLA11279 + Undefined + - + + + DQB1*02:39 + HLA11352 + Undefined + - + + + DQB1*02:40 + HLA11675 + Undefined + - + + + DQB1*02:41 + HLA11883 + Undefined + - + + + DQB1*02:42 + HLA12208 + Undefined + - + + + DQB1*02:43 + HLA12521 + Undefined + - + + + DQB1*02:44 + HLA12522 + Undefined + - + + + DQB1*02:45 + HLA12523 + Undefined + - + + + DQB1*02:46 + HLA12524 + Undefined + - + + + DQB1*02:47 + HLA12525 + Undefined + - + + + DQB1*02:48 + HLA12476 + Undefined + - + + + DQB1*02:49 + HLA12690 + Undefined + - + + + DQB1*02:50 + HLA12797 + Undefined + - + + + DQB1*02:51 + HLA12798 + Undefined + - + + + DQB1*02:52 + HLA12876 + Undefined + - + + + DQB1*02:53Q + HLA12878 + Undefined + - + + + DQB1*02:54 + HLA13125 + Undefined + - + + + DQB1*02:55 + HLA13127 + Undefined + - + + + DQB1*02:56 + HLA13129 + Undefined + - + + + DQB1*02:57 + HLA13230 + Undefined + - + + + DQB1*02:58N + HLA13205 + NotExpressed + Null + + + DQB1*02:59 + HLA13395 + Undefined + - + + + DQB1*02:60 + HLA13680 + Undefined + - + + + DQB1*02:61 + HLA13681 + Undefined + - + + + DQB1*02:62 + HLA13918 + Undefined + - + + + DQB1*02:63 + HLA13925 + Undefined + - + + + DQB1*02:64 + HLA13936 + Undefined + - + + + DQB1*02:65 + HLA14230 + Undefined + - + + + DQB1*02:66 + HLA14759 + Undefined + - + + + DQB1*02:67N + HLA14762 + NotExpressed + Null + + + DQB1*02:68 + HLA15061 + Undefined + - + + + DQB1*02:69 + HLA15062 + Undefined + - + + + DQB1*02:70 + HLA15069 + Undefined + - + + + DQB1*02:71 + HLA15000 + Undefined + - + + + DQB1*02:72 + HLA14955 + Undefined + - + + + DQB1*02:73 + HLA15321 + Undefined + - + + + DQB1*02:74 + HLA15322 + Undefined + - + + + DQB1*02:75 + HLA15478 + Undefined + - + + + DQB1*02:76 + HLA15991 + Undefined + - + + + DQB1*02:77 + HLA15992 + Undefined + - + + + DQB1*02:78 + HLA15993 + Undefined + - + + + DQB1*02:79 + HLA16127 + Undefined + - + + + DQB1*02:80 + HLA16129 + Undefined + - + + + DQB1*02:81 + HLA16137 + Undefined + - + + + DQB1*02:82 + HLA16139 + Undefined + - + + + DQB1*02:83 + HLA16140 + Undefined + - + + + DQB1*02:84 + HLA16187 + Undefined + - + + + DQB1*02:85 + HLA16322 + Undefined + - + + + DQB1*02:86 + HLA16561 + Undefined + - + + + DQB1*02:87 + HLA16562 + Undefined + - + + + DQB1*02:88 + HLA16563 + Undefined + - + + + DQB1*02:89:01 + HLA16643 + Undefined + - + + + DQB1*02:89:02 + HLA20845 + Undefined + - + + + DQB1*02:90 + HLA16775 + Undefined + - + + + DQB1*02:91 + HLA16878 + Undefined + - + + + DQB1*02:92 + HLA16954 + Undefined + - + + + DQB1*02:93 + HLA16955 + Undefined + - + + + DQB1*02:94 + HLA17023 + Undefined + - + + + DQB1*02:95 + HLA17166 + Undefined + - + + + DQB1*02:96N + HLA17196 + NotExpressed + Null + + + DQB1*02:97 + HLA17341 + Undefined + - + + + DQB1*02:98 + HLA17423 + Undefined + - + + + DQB1*02:99 + HLA17424 + Undefined + - + + + DQB1*02:100 + HLA17521 + Undefined + - + + + DQB1*02:101 + HLA17524 + Undefined + - + + + DQB1*02:102 + HLA17607 + Undefined + - + + + DQB1*02:103 + HLA17912 + Undefined + - + + + DQB1*02:104 + HLA18083 + Undefined + - + + + DQB1*02:105 + HLA18109 + Undefined + - + + + DQB1*02:106 + HLA18545 + Undefined + - + + + DQB1*02:107 + HLA19405 + Undefined + - + + + DQB1*02:108 + HLA19280 + Undefined + - + + + DQB1*02:109 + HLA19464 + Undefined + - + + + DQB1*02:110 + HLA19827 + Undefined + - + + + DQB1*02:111 + HLA19946 + Undefined + - + + + DQB1*02:112 + HLA19761 + Undefined + - + + + DQB1*02:113 + HLA21095 + Undefined + - + + + DQB1*02:114 + HLA20521 + Undefined + - + + + DQB1*02:115 + HLA20813 + Undefined + - + + + DQB1*02:116 + HLA20947 + Undefined + - + + + DQB1*02:117 + HLA20707 + Undefined + - + + + DQB1*02:118 + HLA20666 + Undefined + - + + + DQB1*02:119 + HLA20888 + Undefined + - + + + DQB1*02:120 + HLA21151 + Undefined + - + + + DQB1*02:121 + HLA21109 + Undefined + - + + + DQB1*02:122 + HLA20529 + Undefined + - + + + DQB1*02:123 + HLA20864 + Undefined + - + + + DQB1*02:124 + HLA21149 + Undefined + - + + + DQB1*02:125 + HLA21112 + Undefined + - + + + DQB1*02:126 + HLA20578 + Undefined + - + + + DQB1*02:127 + HLA21502 + Undefined + - + + + DQB1*02:128 + HLA21394 + Undefined + - + + + DQB1*02:129N + HLA21614 + NotExpressed + Null + + + DQB1*02:130 + HLA21770 + Undefined + - + + + DQB1*02:131 + HLA21643 + Undefined + - + + + DQB1*02:132N + HLA21826 + NotExpressed + Null + + + DQB1*02:133 + HLA21834 + Undefined + - + + + DQB1*02:134N + HLA21734 + NotExpressed + Null + + + DQB1*02:135 + HLA21665 + Undefined + - + + + DQB1*02:136 + HLA21607 + Undefined + - + + + DQB1*02:137 + HLA21610 + Undefined + - + + + DQB1*02:138 + HLA21794 + Undefined + - + + + DQB1*02:139 + HLA21915 + Undefined + - + + + DQB1*02:140 + HLA21924 + Undefined + - + + + DQB1*02:141 + HLA21934 + Undefined + - + + + DQB1*02:142:01:01 + HLA22354 + Undefined + - + + + DQB1*02:142:01:02 + HLA33828 + Undefined + - + + + DQB1*02:143 + HLA22988 + Undefined + - + + + DQB1*02:144 + HLA22866 + Undefined + - + + + DQB1*02:145 + HLA22843 + Undefined + - + + + DQB1*02:146 + HLA22807 + Undefined + - + + + DQB1*02:147 + HLA23375 + Undefined + - + + + DQB1*02:148 + HLA23042 + Undefined + - + + + DQB1*02:149 + HLA23049 + Undefined + - + + + DQB1*02:150 + HLA23679 + Undefined + - + + + DQB1*02:151 + HLA23470 + Undefined + - + + + DQB1*02:152 + HLA23188 + Undefined + - + + + DQB1*02:153 + HLA23801 + Undefined + - + + + DQB1*02:154 + HLA23467 + Undefined + - + + + DQB1*02:155 + HLA23106 + Undefined + - + + + DQB1*02:156 + HLA23671 + Undefined + - + + + DQB1*02:157 + HLA23882 + Undefined + - + + + DQB1*02:158 + HLA24069 + Undefined + - + + + DQB1*02:159 + HLA24049 + Undefined + - + + + DQB1*02:160 + HLA23833 + Undefined + - + + + DQB1*02:161 + HLA24334 + Undefined + - + + + DQB1*02:162N + HLA24244 + NotExpressed + Null + + + DQB1*02:163N + HLA25100 + NotExpressed + Null + + + DQB1*02:164 + HLA24496 + Undefined + - + + + DQB1*02:165 + HLA25766 + Undefined + - + + + DQB1*02:166 + HLA26153 + Undefined + - + + + DQB1*02:167N + HLA26111 + NotExpressed + Null + + + DQB1*02:168 + HLA26355 + Undefined + - + + + DQB1*02:169 + HLA26618 + Undefined + - + + + DQB1*02:170 + HLA27065 + Undefined + - + + + DQB1*02:171Q + HLA27502 + Undefined + - + + + DQB1*02:172 + HLA27608 + Undefined + - + + + DQB1*02:173 + HLA27774 + Undefined + - + + + DQB1*02:174 + HLA28197 + Undefined + - + + + DQB1*02:175 + HLA28784 + Undefined + - + + + DQB1*02:176N + HLA28557 + NotExpressed + Null + + + DQB1*02:177N + HLA28563 + NotExpressed + Null + + + DQB1*02:178 + HLA28806 + Undefined + - + + + DQB1*02:179 + HLA28809 + Undefined + - + + + DQB1*02:180 + HLA29352 + Undefined + - + + + DQB1*02:181 + HLA29657 + Undefined + - + + + DQB1*02:182 + HLA30769 + Undefined + - + + + DQB1*02:183N + HLA31193 + NotExpressed + Null + + + DQB1*02:184 + HLA31617 + Undefined + - + + + DQB1*02:185 + HLA31411 + Undefined + - + + + DQB1*02:186 + HLA31446 + Undefined + - + + + DQB1*02:187 + HLA31921 + Undefined + - + + + DQB1*02:188 + HLA32231 + Undefined + - + + + DQB1*02:189 + HLA32252 + Undefined + - + + + DQB1*02:190 + HLA32285 + Undefined + - + + + DQB1*02:191 + HLA32257 + Undefined + - + + + DQB1*02:192 + HLA32180 + Undefined + - + + + DQB1*02:193 + HLA32583 + Undefined + - + + + DQB1*02:194N + HLA32584 + NotExpressed + Null + + + DQB1*02:195 + HLA32300 + Undefined + - + + + DQB1*02:196 + HLA33598 + Undefined + - + + + DQB1*02:197 + HLA33796 + Undefined + - + + + DQB1*02:198 + HLA33722 + Undefined + - + + + DQB1*02:199 + HLA34378 + Undefined + - + + + DQB1*02:200 + HLA34357 + Undefined + - + + + DQB1*02:201 + HLA34438 + Undefined + - + + + DQB1*02:202 + HLA34547 + Undefined + - + + + DQB1*02:203 + HLA35205 + Undefined + - + + + DQB1*02:204N + HLA35067 + NotExpressed + Null + + + DQB1*02:205 + HLA36221 + Undefined + - + + + DQB1*02:206N + HLA36257 + NotExpressed + Null + + + DQB1*02:207 + HLA36337 + Undefined + - + + + DQB1*02:208 + HLA36544 + Undefined + - + + + DQB1*02:209 + HLA36366 + Undefined + - + + + DQB1*02:210 + HLA36633 + Undefined + - + + + DQB1*02:211 + HLA36731 + Undefined + - + + + DQB1*02:212 + HLA37092 + Undefined + - + + + DQB1*02:213 + HLA37399 + Undefined + - + + + DQB1*02:214N + HLA38454 + NotExpressed + Null + + + DQB1*03:01:01:01 + HLA00625 + DQ7 + DQ7(3) + + + DQB1*03:01:01:02 + HLA06613 + DQ7 + DQ7(3) + + + DQB1*03:01:01:03 + HLA06616 + DQ7 + DQ7(3) + + + DQB1*03:01:01:04 + HLA15506 + DQ7 + DQ7(3) + + + DQB1*03:01:01:05 + HLA15507 + DQ7 + DQ7(3) + + + DQB1*03:01:01:06 + HLA17162 + DQ7 + DQ7(3) + + + DQB1*03:01:01:07 + HLA17167 + DQ7 + DQ7(3) + + + DQB1*03:01:01:08 + HLA17197 + DQ7 + DQ7(3) + + + DQB1*03:01:01:09 + HLA17335 + DQ7 + DQ7(3) + + + DQB1*03:01:01:10 + HLA17365 + DQ7 + DQ7(3) + + + DQB1*03:01:01:11 + HLA17366 + DQ7 + DQ7(3) + + + DQB1*03:01:01:12 + HLA17367 + DQ7 + DQ7(3) + + + DQB1*03:01:01:14 + HLA17369 + DQ7 + DQ7(3) + + + DQB1*03:01:01:15 + HLA17460 + DQ7 + DQ7(3) + + + DQB1*03:01:01:16 + HLA17461 + DQ7 + DQ7(3) + + + DQB1*03:01:01:17 + HLA17462 + DQ7 + DQ7(3) + + + DQB1*03:01:01:18 + HLA17466 + DQ7 + DQ7(3) + + + DQB1*03:01:01:19 + HLA17597 + DQ7 + DQ7(3) + + + DQB1*03:01:01:20 + HLA18096 + DQ7 + DQ7(3) + + + DQB1*03:01:01:21N + HLA23504 + NotExpressed + Null + + + DQB1*03:01:01:22 + HLA25342 + DQ7 + DQ7(3) + + + DQB1*03:01:01:23 + HLA26325 + DQ7 + DQ7(3) + + + DQB1*03:01:01:24 + HLA26915 + DQ7 + DQ7(3) + + + DQB1*03:01:01:25 + HLA29233 + DQ7 + DQ7(3) + + + DQB1*03:01:01:26 + HLA29234 + DQ7 + DQ7(3) + + + DQB1*03:01:01:27 + HLA30587 + DQ7 + DQ7(3) + + + DQB1*03:01:01:28 + HLA30841 + DQ7 + DQ7(3) + + + DQB1*03:01:01:29 + HLA31034 + DQ7 + DQ7(3) + + + DQB1*03:01:01:30 + HLA31167 + DQ7 + DQ7(3) + + + DQB1*03:01:01:31 + HLA32100 + DQ7 + DQ7(3) + + + DQB1*03:01:01:32 + HLA32130 + DQ7 + DQ7(3) + + + DQB1*03:01:01:33 + HLA31856 + DQ7 + DQ7(3) + + + DQB1*03:01:01:34 + HLA31843 + DQ7 + DQ7(3) + + + DQB1*03:01:01:35 + HLA32276 + DQ7 + DQ7(3) + + + DQB1*03:01:01:36 + HLA32465 + DQ7 + DQ7(3) + + + DQB1*03:01:01:37 + HLA33811 + DQ7 + DQ7(3) + + + DQB1*03:01:01:38 + HLA33751 + DQ7 + DQ7(3) + + + DQB1*03:01:01:39 + HLA33986 + DQ7 + DQ7(3) + + + DQB1*03:01:01:40 + HLA34170 + DQ7 + DQ7(3) + + + DQB1*03:01:01:41 + HLA34388 + DQ7 + DQ7(3) + + + DQB1*03:01:01:42 + HLA34951 + DQ7 + DQ7(3) + + + DQB1*03:01:01:43 + HLA35180 + DQ7 + DQ7(3) + + + DQB1*03:01:01:44 + HLA35170 + DQ7 + DQ7(3) + + + DQB1*03:01:01:45 + HLA35406 + DQ7 + DQ7(3) + + + DQB1*03:01:01:46 + HLA35385 + DQ7 + DQ7(3) + + + DQB1*03:01:01:47 + HLA35592 + DQ7 + DQ7(3) + + + DQB1*03:01:01:48 + HLA36254 + DQ7 + DQ7(3) + + + DQB1*03:01:01:49 + HLA36364 + DQ7 + DQ7(3) + + + DQB1*03:01:01:50 + HLA36350 + DQ7 + DQ7(3) + + + DQB1*03:01:01:51 + HLA36375 + DQ7 + DQ7(3) + + + DQB1*03:01:01:52 + HLA36400 + DQ7 + DQ7(3) + + + DQB1*03:01:01:53 + HLA36712 + DQ7 + DQ7(3) + + + DQB1*03:01:01:54 + HLA36900 + DQ7 + DQ7(3) + + + DQB1*03:01:01:55 + HLA36791 + DQ7 + DQ7(3) + + + DQB1*03:01:01:56 + HLA37327 + DQ7 + DQ7(3) + + + DQB1*03:01:01:57 + HLA37290 + DQ7 + DQ7(3) + + + DQB1*03:01:01:58 + HLA37231 + DQ7 + DQ7(3) + + + DQB1*03:01:02 + HLA00626 + DQ7 + DQ7(3) + + + DQB1*03:01:03 + HLA02688 + DQ7 + DQ7(3) + + + DQB1*03:01:04:01 + HLA03175 + DQ7 + DQ7(3) + + + DQB1*03:01:04:02 + HLA28776 + DQ7 + DQ7(3) + + + DQB1*03:01:05 + HLA05773 + DQ7 + DQ7(3) + + + DQB1*03:01:06 + HLA06142 + DQ7 + DQ7(3) + + + DQB1*03:01:07 + HLA09094 + DQ7 + DQ7(3) + + + DQB1*03:01:08 + HLA09096 + DQ7 + DQ7(3) + + + DQB1*03:01:09 + HLA09147 + DQ7 + DQ7(3) + + + DQB1*03:01:10 + HLA09148 + DQ7 + DQ7(3) + + + DQB1*03:01:11 + HLA09149 + DQ7 + DQ7(3) + + + DQB1*03:01:12 + HLA09170 + DQ7 + DQ7(3) + + + DQB1*03:01:13 + HLA09233 + DQ7 + DQ7(3) + + + DQB1*03:01:14 + HLA09235 + DQ7 + DQ7(3) + + + DQB1*03:01:15 + HLA09239 + DQ7 + DQ7(3) + + + DQB1*03:01:16 + HLA09242 + DQ7 + DQ7(3) + + + DQB1*03:01:17 + HLA09634 + DQ7 + DQ7(3) + + + DQB1*03:01:18 + HLA09639 + DQ7 + DQ7(3) + + + DQB1*03:01:19 + HLA09772 + DQ7 + DQ7(3) + + + DQB1*03:01:20 + HLA09840 + DQ7 + DQ7(3) + + + DQB1*03:01:21 + HLA10209 + DQ7 + DQ7(3) + + + DQB1*03:01:22 + HLA10540 + DQ7 + DQ7(3) + + + DQB1*03:01:23 + HLA11132 + DQ7 + DQ7(3) + + + DQB1*03:01:24 + HLA11349 + DQ7 + DQ7(3) + + + DQB1*03:01:25 + HLA12351 + DQ7 + DQ7(3) + + + DQB1*03:01:26 + HLA12737 + DQ7 + DQ7(3) + + + DQB1*03:01:27 + HLA12794 + DQ7 + DQ7(3) + + + DQB1*03:01:28 + HLA12796 + DQ7 + DQ7(3) + + + DQB1*03:01:29 + HLA13122 + DQ7 + DQ7(3) + + + DQB1*03:01:30 + HLA13622 + DQ7 + DQ7(3) + + + DQB1*03:01:31 + HLA13926 + DQ7 + DQ7(3) + + + DQB1*03:01:32 + HLA14637 + DQ7 + DQ7(3) + + + DQB1*03:01:33 + HLA14778 + DQ7 + DQ7(3) + + + DQB1*03:01:34 + HLA15778 + DQ7 + DQ7(3) + + + DQB1*03:01:35 + HLA16125 + DQ7 + DQ7(3) + + + DQB1*03:01:36 + HLA16162 + DQ7 + DQ7(3) + + + DQB1*03:01:37 + HLA16168 + DQ7 + DQ7(3) + + + DQB1*03:01:38 + HLA17148 + DQ7 + DQ7(3) + + + DQB1*03:01:39 + HLA17294 + DQ7 + DQ7(3) + + + DQB1*03:01:40 + HLA18135 + DQ7 + DQ7(3) + + + DQB1*03:01:41 + HLA18839 + DQ7 + DQ7(3) + + + DQB1*03:01:42 + HLA19678 + DQ7 + DQ7(3) + + + DQB1*03:01:43 + HLA19829 + DQ7 + DQ7(3) + + + DQB1*03:01:44 + HLA19760 + DQ7 + DQ7(3) + + + DQB1*03:01:45 + HLA21434 + DQ7 + DQ7(3) + + + DQB1*03:01:46 + HLA21919 + DQ7 + DQ7(3) + + + DQB1*03:01:47 + HLA22886 + DQ7 + DQ7(3) + + + DQB1*03:01:48 + HLA25748 + DQ7 + DQ7(3) + + + DQB1*03:01:49 + HLA27803 + DQ7 + DQ7(3) + + + DQB1*03:01:50 + HLA30821 + DQ7 + DQ7(3) + + + DQB1*03:01:51 + HLA32143 + DQ7 + DQ7(3) + + + DQB1*03:01:52 + HLA32132 + DQ7 + DQ7(3) + + + DQB1*03:01:53 + HLA32247 + DQ7 + DQ7(3) + + + DQB1*03:01:54 + HLA32263 + DQ7 + DQ7(3) + + + DQB1*03:01:55 + HLA34366 + DQ7 + DQ7(3) + + + DQB1*03:01:56 + HLA35768 + DQ7 + DQ7(3) + + + DQB1*03:01:57 + HLA36391 + DQ7 + DQ7(3) + + + DQB1*03:01:58 + HLA36351 + DQ7 + DQ7(3) + + + DQB1*03:02:01:01 + HLA00627 + DQ8 + DQ8(3) + + + DQB1*03:02:01:02 + HLA15503 + DQ8 + DQ8(3) + + + DQB1*03:02:01:03 + HLA17198 + DQ8 + DQ8(3) + + + DQB1*03:02:01:04 + HLA17313 + DQ8 + DQ8(3) + + + DQB1*03:02:01:05 + HLA17598 + DQ8 + DQ8(3) + + + DQB1*03:02:01:06 + HLA17600 + DQ8 + DQ8(3) + + + DQB1*03:02:01:07 + HLA22733 + DQ8 + DQ8(3) + + + DQB1*03:02:01:08 + HLA22716 + DQ8 + DQ8(3) + + + DQB1*03:02:01:09 + HLA28774 + DQ8 + DQ8(3) + + + DQB1*03:02:01:10 + HLA29165 + DQ8 + DQ8(3) + + + DQB1*03:02:01:11 + HLA33685 + DQ8 + DQ8(3) + + + DQB1*03:02:01:12 + HLA33750 + DQ8 + DQ8(3) + + + DQB1*03:02:01:13 + HLA34725 + DQ8 + DQ8(3) + + + DQB1*03:02:01:14 + HLA35562 + DQ8 + DQ8(3) + + + DQB1*03:02:01:15 + HLA35401 + DQ8 + DQ8(3) + + + DQB1*03:02:01:16 + HLA36352 + DQ8 + DQ8(3) + + + DQB1*03:02:01:17 + HLA36703 + DQ8 + DQ8(3) + + + DQB1*03:02:01:18 + HLA36696 + DQ8 + DQ8(3) + + + DQB1*03:02:01:19 + HLA37383 + DQ8 + DQ8(3) + + + DQB1*03:02:01:20 + HLA37629 + DQ8 + DQ8(3) + + + DQB1*03:02:01:21 + HLA37893 + DQ8 + DQ8(3) + + + DQB1*03:02:02:01 + HLA01770 + DQ8 + DQ8(3) + + + DQB1*03:02:02:02 + HLA34000 + DQ8 + DQ8(3) + + + DQB1*03:02:03 + HLA02625 + DQ8 + DQ8(3) + + + DQB1*03:02:04 + HLA02722 + DQ8 + DQ8(3) + + + DQB1*03:02:05 + HLA05108 + DQ8 + DQ8(3) + + + DQB1*03:02:06 + HLA09285 + DQ8 + DQ8(3) + + + DQB1*03:02:07 + HLA09288 + DQ8 + DQ8(3) + + + DQB1*03:02:08 + HLA09741 + DQ8 + DQ8(3) + + + DQB1*03:02:09 + HLA09846 + DQ8 + DQ8(3) + + + DQB1*03:02:10 + HLA10030 + DQ8 + DQ8(3) + + + DQB1*03:02:11 + HLA10216 + DQ8 + DQ8(3) + + + DQB1*03:02:12 + HLA10217 + DQ8 + DQ8(3) + + + DQB1*03:02:13 + HLA10283 + DQ8 + DQ8(3) + + + DQB1*03:02:14 + HLA11282 + DQ8 + DQ8(3) + + + DQB1*03:02:15 + HLA11887 + DQ8 + DQ8(3) + + + DQB1*03:02:16 + HLA12029 + DQ8 + DQ8(3) + + + DQB1*03:02:17 + HLA12035 + DQ8 + DQ8(3) + + + DQB1*03:02:18 + HLA13138 + DQ8 + DQ8(3) + + + DQB1*03:02:19 + HLA13140 + DQ8 + DQ8(3) + + + DQB1*03:02:20 + HLA15584 + DQ8 + DQ8(3) + + + DQB1*03:02:21 + HLA16146 + DQ8 + DQ8(3) + + + DQB1*03:02:22 + HLA16148 + DQ8 + DQ8(3) + + + DQB1*03:02:23 + HLA16157 + DQ8 + DQ8(3) + + + DQB1*03:02:24 + HLA16158 + DQ8 + DQ8(3) + + + DQB1*03:02:25 + HLA17347 + DQ8 + DQ8(3) + + + DQB1*03:02:26 + HLA17692 + DQ8 + DQ8(3) + + + DQB1*03:02:27 + HLA18643 + DQ8 + DQ8(3) + + + DQB1*03:02:28 + HLA18691 + DQ8 + DQ8(3) + + + DQB1*03:02:29 + HLA18699 + DQ8 + DQ8(3) + + + DQB1*03:02:30 + HLA18807 + DQ8 + DQ8(3) + + + DQB1*03:02:31 + HLA26185 + DQ8 + DQ8(3) + + + DQB1*03:02:32 + HLA26887 + DQ8 + DQ8(3) + + + DQB1*03:02:33 + HLA27785 + DQ8 + DQ8(3) + + + DQB1*03:02:34 + HLA29432 + DQ8 + DQ8(3) + + + DQB1*03:02:35 + HLA31649 + DQ8 + DQ8(3) + + + DQB1*03:02:36 + HLA34043 + DQ8 + DQ8(3) + + + DQB1*03:02:37 + HLA36392 + DQ8 + DQ8(3) + + + DQB1*03:02:38 + HLA37627 + DQ8 + DQ8(3) + + + DQB1*03:02:39 + HLA38445 + DQ8 + DQ8(3) + + + DQB1*03:03:02:01 + HLA00629 + DQ9 + DQ9(3) + + + DQB1*03:03:02:02 + HLA06620 + DQ9 + DQ9(3) + + + DQB1*03:03:02:03 + HLA06623 + DQ9 + DQ9(3) + + + DQB1*03:03:02:04 + HLA12588 + DQ9 + DQ9(3) + + + DQB1*03:03:02:05 + HLA17787 + DQ9 + DQ9(3) + + + DQB1*03:03:02:06 + HLA32144 + DQ9 + DQ9(3) + + + DQB1*03:03:02:07 + HLA32128 + DQ9 + DQ9(3) + + + DQB1*03:03:02:08 + HLA33741 + DQ9 + DQ9(3) + + + DQB1*03:03:02:09 + HLA34015 + DQ9 + DQ9(3) + + + DQB1*03:03:02:10 + HLA36098 + DQ9 + DQ9(3) + + + DQB1*03:03:02:11 + HLA36579 + DQ9 + DQ9(3) + + + DQB1*03:03:02:12 + HLA38167 + DQ9 + DQ9(3) + + + DQB1*03:03:02:13 + HLA38155 + DQ9 + DQ9(3) + + + DQB1*03:03:02:14 + HLA38544 + DQ9 + DQ9(3) + + + DQB1*03:03:03:01 + HLA01004 + DQ9 + DQ9(3) + + + DQB1*03:03:03:02 + HLA28777 + DQ9 + DQ9(3) + + + DQB1*03:03:04 + HLA06822 + DQ9 + DQ9(3) + + + DQB1*03:03:05 + HLA09281 + DQ9 + DQ9(3) + + + DQB1*03:03:06 + HLA09283 + DQ9 + DQ9(3) + + + DQB1*03:03:07 + HLA09650 + DQ9 + DQ9(3) + + + DQB1*03:03:08 + HLA10016 + DQ9 + DQ9(3) + + + DQB1*03:03:09 + HLA10223 + DQ9 + DQ9(3) + + + DQB1*03:03:10 + HLA10227 + DQ9 + DQ9(3) + + + DQB1*03:03:11 + HLA10280 + DQ9 + DQ9(3) + + + DQB1*03:03:12 + HLA10538 + DQ9 + DQ9(3) + + + DQB1*03:03:13 + HLA11979 + DQ9 + DQ9(3) + + + DQB1*03:03:14 + HLA17425 + DQ9 + DQ9(3) + + + DQB1*03:03:15 + HLA17446 + DQ9 + DQ9(3) + + + DQB1*03:03:16 + HLA18159 + DQ9 + DQ9(3) + + + DQB1*03:03:17 + HLA19908 + DQ9 + DQ9(3) + + + DQB1*03:03:18 + HLA19692 + DQ9 + DQ9(3) + + + DQB1*03:03:19 + HLA21014 + DQ9 + DQ9(3) + + + DQB1*03:03:20 + HLA20903 + DQ9 + DQ9(3) + + + DQB1*03:03:21 + HLA21243 + DQ9 + DQ9(3) + + + DQB1*03:03:22 + HLA23522 + DQ9 + DQ9(3) + + + DQB1*03:03:23 + HLA23352 + DQ9 + DQ9(3) + + + DQB1*03:03:24 + HLA23506 + DQ9 + DQ9(3) + + + DQB1*03:03:25 + HLA25378 + DQ9 + DQ9(3) + + + DQB1*03:03:26 + HLA26191 + DQ9 + DQ9(3) + + + DQB1*03:03:27 + HLA27604 + DQ9 + DQ9(3) + + + DQB1*03:03:28 + HLA33630 + DQ9 + DQ9(3) + + + DQB1*03:03:29 + HLA36124 + DQ9 + DQ9(3) + + + DQB1*03:03:30 + HLA36942 + DQ9 + DQ9(3) + + + DQB1*03:04:01:01 + HLA00630 + DQ7 + DQ7(3) + + + DQB1*03:04:01:02 + HLA27883 + DQ7 + DQ7(3) + + + DQB1*03:04:02 + HLA11278 + DQ7 + DQ7(3) + + + DQB1*03:04:03 + HLA16154 + DQ7 + DQ7(3) + + + DQB1*03:04:04 + HLA20649 + DQ7 + DQ7(3) + + + DQB1*03:05:01 + HLA00631 + DQ8 + DQ8(3) + + + DQB1*03:05:02 + HLA01443 + DQ8 + DQ8(3) + + + DQB1*03:05:03 + HLA01744 + DQ8 + DQ8(3) + + + DQB1*03:05:04 + HLA02497 + DQ8 + DQ8(3) + + + DQB1*03:05:05 + HLA23404 + DQ8 + DQ8(3) + + + DQB1*03:06 + HLA00632 + DQ3 + DQ3 + + + DQB1*03:07 + HLA00633 + DQ8 + - + + + DQB1*03:08 + HLA00634 + DQ8 + - + + + DQB1*03:09 + HLA00635 + DQ7 + - + + + DQB1*03:10:01 + HLA01164 + DQ3 + DQ8(3) + + + DQB1*03:10:02:01 + HLA10276 + DQ3 + DQ8(3) + + + DQB1*03:10:02:02 + HLA17695 + DQ3 + DQ8(3) + + + DQB1*03:10:03 + HLA24819 + DQ3 + DQ8(3) + + + DQB1*03:11 + HLA01538 + DQ8 + - + + + DQB1*03:12 + HLA01574 + DQ9 + - + + + DQB1*03:13 + HLA01589 + DQ7 + - + + + DQB1*03:14:01 + HLA02026 + DQ3 + - + + + DQB1*03:14:02 + HLA09240 + DQ3 + - + + + DQB1*03:15 + HLA02029 + DQ9 + - + + + DQB1*03:16 + HLA02208 + DQ7 + - + + + DQB1*03:17:01 + HLA02323 + DQ9 + - + + + DQB1*03:17:02 + HLA09470 + DQ9 + - + + + DQB1*03:18 + HLA02372 + DQ8 + - + + + DQB1*03:19:01:01 + HLA02690 + DQ7 + - + + + DQB1*03:19:01:02Q + HLA25687 + Undefined + - + + + DQB1*03:19:02 + HLA14650 + DQ7 + - + + + DQB1*03:19:03 + HLA20855 + DQ7 + - + + + DQB1*03:19:04 + HLA21728 + DQ7 + - + + + DQB1*03:19:05 + HLA30318 + DQ7 + - + + + DQB1*03:19:06 + HLA34352 + DQ7 + - + + + DQB1*03:20 + HLA02887 + DQ9 + - + + + DQB1*03:21 + HLA03174 + Undefined + - + + + DQB1*03:22:01:01 + HLA03295 + Undefined + - + + + DQB1*03:22:01:02 + HLA28471 + Undefined + - + + + DQB1*03:22:02 + HLA22778 + Undefined + - + + + DQB1*03:23:01 + HLA03451 + Undefined + - + + + DQB1*03:23:02 + HLA13580 + Undefined + - + + + DQB1*03:23:03 + HLA18093 + Undefined + - + + + DQB1*03:24 + HLA03596 + Undefined + - + + + DQB1*03:25:01 + HLA03745 + Undefined + - + + + DQB1*03:25:02 + HLA15002 + Undefined + - + + + DQB1*03:26 + HLA04356 + Undefined + - + + + DQB1*03:27 + HLA05374 + Undefined + - + + + DQB1*03:28 + HLA05767 + Undefined + - + + + DQB1*03:29 + HLA05771 + Undefined + - + + + DQB1*03:30 + HLA05774 + Undefined + - + + + DQB1*03:31 + HLA05761 + Undefined + - + + + DQB1*03:32 + HLA06143 + Undefined + - + + + DQB1*03:33 + HLA06144 + Undefined + - + + + DQB1*03:34 + HLA06145 + Undefined + - + + + DQB1*03:35 + HLA06176 + Undefined + - + + + DQB1*03:36 + HLA06177 + Undefined + - + + + DQB1*03:37 + HLA06516 + Undefined + - + + + DQB1*03:38:01 + HLA06880 + Undefined + - + + + DQB1*03:38:02 + HLA22330 + Undefined + - + + + DQB1*03:39 + HLA07411 + Undefined + - + + + DQB1*03:40 + HLA07799 + Undefined + - + + + DQB1*03:41 + HLA08084 + Undefined + - + + + DQB1*03:42 + HLA08113 + Undefined + - + + + DQB1*03:43 + HLA08246 + Undefined + - + + + DQB1*03:44 + HLA08289 + Undefined + - + + + DQB1*03:45:01 + HLA08955 + Undefined + - + + + DQB1*03:45:02 + HLA23270 + Undefined + - + + + DQB1*03:46 + HLA09093 + Undefined + - + + + DQB1*03:47 + HLA09095 + Undefined + - + + + DQB1*03:48 + HLA09129 + Undefined + - + + + DQB1*03:49:01:01 + HLA09143 + Undefined + - + + + DQB1*03:49:01:02 + HLA28469 + Undefined + - + + + DQB1*03:50 + HLA09144 + Undefined + - + + + DQB1*03:51 + HLA09145 + Undefined + - + + + DQB1*03:52 + HLA09220 + Undefined + - + + + DQB1*03:53 + HLA09228 + Undefined + - + + + DQB1*03:54 + HLA09231 + Undefined + - + + + DQB1*03:55 + HLA09232 + Undefined + - + + + DQB1*03:56 + HLA09234 + Undefined + - + + + DQB1*03:57 + HLA09236 + Undefined + - + + + DQB1*03:58 + HLA09237 + Undefined + - + + + DQB1*03:59 + HLA09238 + Undefined + - + + + DQB1*03:60 + HLA09241 + Undefined + - + + + DQB1*03:61 + HLA09261 + Undefined + - + + + DQB1*03:62 + HLA09263 + Undefined + - + + + DQB1*03:63 + HLA09279 + Undefined + - + + + DQB1*03:64 + HLA09280 + Undefined + - + + + DQB1*03:65 + HLA09282 + Undefined + - + + + DQB1*03:66N + HLA09284 + NotExpressed + Null + + + DQB1*03:67 + HLA09286 + Undefined + - + + + DQB1*03:68 + HLA09287 + Undefined + - + + + DQB1*03:69 + HLA09289 + Undefined + - + + + DQB1*03:70 + HLA09230 + Undefined + - + + + DQB1*03:71 + HLA09356 + Undefined + - + + + DQB1*03:72 + HLA09360 + Undefined + - + + + DQB1*03:73 + HLA09566 + Undefined + - + + + DQB1*03:74 + HLA09635 + Undefined + - + + + DQB1*03:75 + HLA09636 + Undefined + - + + + DQB1*03:76 + HLA09637 + Undefined + - + + + DQB1*03:77 + HLA09638 + Undefined + - + + + DQB1*03:78 + HLA09640 + Undefined + - + + + DQB1*03:79 + HLA09653 + Undefined + - + + + DQB1*03:80 + HLA09654 + Undefined + - + + + DQB1*03:81 + HLA09732 + Undefined + - + + + DQB1*03:82 + HLA09773 + Undefined + - + + + DQB1*03:83 + HLA09837 + Undefined + - + + + DQB1*03:84N + HLA09842 + NotExpressed + Null + + + DQB1*03:85 + HLA09844 + Undefined + - + + + DQB1*03:86 + HLA09848 + Undefined + - + + + DQB1*03:87 + HLA09850 + Undefined + - + + + DQB1*03:88 + HLA09852 + Undefined + - + + + DQB1*03:89 + HLA09854 + Undefined + - + + + DQB1*03:90N + HLA09941 + NotExpressed + Null + + + DQB1*03:91Q + HLA10195 + Undefined + - + + + DQB1*03:92 + HLA10210 + Undefined + - + + + DQB1*03:93 + HLA10211 + Undefined + - + + + DQB1*03:94 + HLA10214 + Undefined + - + + + DQB1*03:95N + HLA10219 + NotExpressed + Null + + + DQB1*03:96 + HLA10221 + Undefined + - + + + DQB1*03:97 + HLA10225 + Undefined + - + + + DQB1*03:98 + HLA10229 + Undefined + - + + + DQB1*03:99Q + HLA10231 + Undefined + - + + + DQB1*03:100 + HLA10233 + Undefined + - + + + DQB1*03:101 + HLA10274 + Undefined + - + + + DQB1*03:102 + HLA10275 + Undefined + - + + + DQB1*03:103 + HLA10277 + Undefined + - + + + DQB1*03:104 + HLA10284 + Undefined + - + + + DQB1*03:105 + HLA10285 + Undefined + - + + + DQB1*03:106 + HLA10286 + Undefined + - + + + DQB1*03:107 + HLA10287 + Undefined + - + + + DQB1*03:108 + HLA10539 + Undefined + - + + + DQB1*03:109 + HLA10541 + Undefined + - + + + DQB1*03:110 + HLA10546 + Undefined + - + + + DQB1*03:111 + HLA10547 + Undefined + - + + + DQB1*03:112 + HLA10548 + Undefined + - + + + DQB1*03:113 + HLA10663 + Undefined + - + + + DQB1*03:114 + HLA10928 + Undefined + - + + + DQB1*03:115 + HLA11056 + Undefined + - + + + DQB1*03:116 + HLA11078 + Undefined + - + + + DQB1*03:117 + HLA11079 + Undefined + - + + + DQB1*03:118N + HLA11127 + NotExpressed + Null + + + DQB1*03:119 + HLA11128 + Undefined + - + + + DQB1*03:120 + HLA11129 + Undefined + - + + + DQB1*03:121 + HLA11130 + Undefined + - + + + DQB1*03:122 + HLA11131 + Undefined + - + + + DQB1*03:123 + HLA11141 + Undefined + - + + + DQB1*03:124 + HLA11142 + Undefined + - + + + DQB1*03:125 + HLA11143 + Undefined + - + + + DQB1*03:126 + HLA11144 + Undefined + - + + + DQB1*03:127 + HLA11272 + Undefined + - + + + DQB1*03:128 + HLA11274 + Undefined + - + + + DQB1*03:129 + HLA11275 + Undefined + - + + + DQB1*03:130 + HLA11276 + Undefined + - + + + DQB1*03:131 + HLA11277 + Undefined + - + + + DQB1*03:132 + HLA11558 + Undefined + - + + + DQB1*03:133 + HLA11348 + Undefined + - + + + DQB1*03:134 + HLA11350 + Undefined + - + + + DQB1*03:135 + HLA11351 + Undefined + - + + + DQB1*03:136 + HLA11356 + Undefined + - + + + DQB1*03:137 + HLA11357 + Undefined + - + + + DQB1*03:138 + HLA11358 + Undefined + - + + + DQB1*03:139 + HLA11586 + Undefined + - + + + DQB1*03:140 + HLA11587 + Undefined + - + + + DQB1*03:141 + HLA11591 + Undefined + - + + + DQB1*03:142 + HLA11598 + Undefined + - + + + DQB1*03:143 + HLA11671 + Undefined + - + + + DQB1*03:144 + HLA11672 + Undefined + - + + + DQB1*03:145 + HLA11678 + Undefined + - + + + DQB1*03:146 + HLA11881 + Undefined + - + + + DQB1*03:147 + HLA11882 + Undefined + - + + + DQB1*03:148 + HLA12027 + Undefined + - + + + DQB1*03:149 + HLA12028 + Undefined + - + + + DQB1*03:150 + HLA12046 + Undefined + - + + + DQB1*03:151 + HLA12206 + Undefined + - + + + DQB1*03:152 + HLA12207 + Undefined + - + + + DQB1*03:153 + HLA12211 + Undefined + - + + + DQB1*03:154 + HLA12352 + Undefined + - + + + DQB1*03:155 + HLA12355 + Undefined + - + + + DQB1*03:156 + HLA12356 + Undefined + - + + + DQB1*03:157 + HLA12359 + Undefined + - + + + DQB1*03:158 + HLA12518 + Undefined + - + + + DQB1*03:159 + HLA12519 + Undefined + - + + + DQB1*03:160 + HLA12520 + Undefined + - + + + DQB1*03:161 + HLA12529 + Undefined + - + + + DQB1*03:162 + HLA12474 + Undefined + - + + + DQB1*03:163 + HLA12478 + Undefined + - + + + DQB1*03:164 + HLA12573 + Undefined + - + + + DQB1*03:165 + HLA12574 + Undefined + - + + + DQB1*03:166 + HLA12788 + Undefined + - + + + DQB1*03:167 + HLA12795 + Undefined + - + + + DQB1*03:168 + HLA12893 + Undefined + - + + + DQB1*03:169 + HLA13051 + Undefined + - + + + DQB1*03:170 + HLA13118 + Undefined + - + + + DQB1*03:171 + HLA13119 + Undefined + - + + + DQB1*03:172 + HLA13120 + Undefined + - + + + DQB1*03:173 + HLA13121 + Undefined + - + + + DQB1*03:174 + HLA13123 + Undefined + - + + + DQB1*03:175 + HLA13135 + Undefined + - + + + DQB1*03:176 + HLA13136 + Undefined + - + + + DQB1*03:177 + HLA13137 + Undefined + - + + + DQB1*03:178 + HLA13139 + Undefined + - + + + DQB1*03:179 + HLA13246 + Undefined + - + + + DQB1*03:180 + HLA13332 + Undefined + - + + + DQB1*03:181 + HLA13380 + Undefined + - + + + DQB1*03:182 + HLA13386 + Undefined + - + + + DQB1*03:183 + HLA13578 + Undefined + - + + + DQB1*03:184 + HLA13579 + Undefined + - + + + DQB1*03:185 + HLA13581 + Undefined + - + + + DQB1*03:186 + HLA13500 + Undefined + - + + + DQB1*03:187 + HLA13678 + Undefined + - + + + DQB1*03:188 + HLA13679 + Undefined + - + + + DQB1*03:189 + HLA13682 + Undefined + - + + + DQB1*03:190 + HLA13708 + Undefined + - + + + DQB1*03:191 + HLA13711 + Undefined + - + + + DQB1*03:192 + HLA13809 + Undefined + - + + + DQB1*03:193 + HLA13880 + Undefined + - + + + DQB1*03:194 + HLA13881 + Undefined + - + + + DQB1*03:195 + HLA13919 + Undefined + - + + + DQB1*03:196 + HLA13929 + Undefined + - + + + DQB1*03:197Q + HLA13930 + Undefined + - + + + DQB1*03:198:01 + HLA13931 + Undefined + - + + + DQB1*03:198:02 + HLA21709 + Undefined + - + + + DQB1*03:199 + HLA13938 + Undefined + - + + + DQB1*03:200 + HLA13761 + Undefined + - + + + DQB1*03:201 + HLA14035 + Undefined + - + + + DQB1*03:202 + HLA14036 + Undefined + - + + + DQB1*03:203 + HLA14037 + Undefined + - + + + DQB1*03:204 + HLA14039 + Undefined + - + + + DQB1*03:205 + HLA14040 + Undefined + - + + + DQB1*03:206 + HLA13993 + Undefined + - + + + DQB1*03:207 + HLA14160 + Undefined + - + + + DQB1*03:208 + HLA14162 + Undefined + - + + + DQB1*03:209 + HLA14163 + Undefined + - + + + DQB1*03:210 + HLA14165 + Undefined + - + + + DQB1*03:211 + HLA14166 + Undefined + - + + + DQB1*03:212 + HLA14167 + Undefined + - + + + DQB1*03:213N + HLA14168 + NotExpressed + Null + + + DQB1*03:214 + HLA14169 + Undefined + - + + + DQB1*03:215 + HLA14171 + Undefined + - + + + DQB1*03:216 + HLA14345 + Undefined + - + + + DQB1*03:217 + HLA14346 + Undefined + - + + + DQB1*03:218 + HLA14202 + Undefined + - + + + DQB1*03:219 + HLA14547 + Undefined + - + + + DQB1*03:220 + HLA14549 + Undefined + - + + + DQB1*03:221 + HLA14550 + Undefined + - + + + DQB1*03:222 + HLA14633 + Undefined + - + + + DQB1*03:223 + HLA14760 + Undefined + - + + + DQB1*03:224 + HLA14761 + Undefined + - + + + DQB1*03:225 + HLA15063 + Undefined + - + + + DQB1*03:226 + HLA15064 + Undefined + - + + + DQB1*03:227 + HLA15067 + Undefined + - + + + DQB1*03:228 + HLA15068 + Undefined + - + + + DQB1*03:229 + HLA15001 + Undefined + - + + + DQB1*03:230 + HLA15324 + Undefined + - + + + DQB1*03:231 + HLA15476 + Undefined + - + + + DQB1*03:232 + HLA15477 + Undefined + - + + + DQB1*03:233 + HLA15480 + Undefined + - + + + DQB1*03:234 + HLA15481 + Undefined + - + + + DQB1*03:235 + HLA15679 + Undefined + - + + + DQB1*03:236 + HLA15680 + Undefined + - + + + DQB1*03:237N + HLA15683 + NotExpressed + Null + + + DQB1*03:238 + HLA15684 + Undefined + - + + + DQB1*03:239 + HLA15685 + Undefined + - + + + DQB1*03:240 + HLA15686 + Undefined + - + + + DQB1*03:241 + HLA15598 + Undefined + - + + + DQB1*03:242 + HLA15599 + Undefined + - + + + DQB1*03:243 + HLA15585 + Undefined + - + + + DQB1*03:244 + HLA16048 + Undefined + - + + + DQB1*03:245 + HLA16124 + Undefined + - + + + DQB1*03:246 + HLA16128 + Undefined + - + + + DQB1*03:247 + HLA16130 + Undefined + - + + + DQB1*03:248 + HLA16131 + Undefined + - + + + DQB1*03:249 + HLA16132 + Undefined + - + + + DQB1*03:250 + HLA16136 + Undefined + - + + + DQB1*03:251 + HLA16143 + Undefined + - + + + DQB1*03:252 + HLA16160 + Undefined + - + + + DQB1*03:253 + HLA16163 + Undefined + - + + + DQB1*03:254 + HLA16190 + Undefined + - + + + DQB1*03:255 + HLA16346 + Undefined + - + + + DQB1*03:256 + HLA16559 + Undefined + - + + + DQB1*03:257 + HLA16774 + Undefined + - + + + DQB1*03:258 + HLA16778 + Undefined + - + + + DQB1*03:259 + HLA16777 + Undefined + - + + + DQB1*03:260 + HLA16953 + Undefined + - + + + DQB1*03:261 + HLA16957 + Undefined + - + + + DQB1*03:262 + HLA17024 + Undefined + - + + + DQB1*03:263:01:01 + HLA17064 + Undefined + - + + + DQB1*03:263:01:02 + HLA28813 + Undefined + - + + + DQB1*03:264 + HLA17203 + Undefined + - + + + DQB1*03:265 + HLA17215 + Undefined + - + + + DQB1*03:266 + HLA17443 + Undefined + - + + + DQB1*03:267 + HLA17519 + Undefined + - + + + DQB1*03:268 + HLA17520 + Undefined + - + + + DQB1*03:269N + HLA17523 + NotExpressed + Null + + + DQB1*03:270 + HLA17906 + Undefined + - + + + DQB1*03:271 + HLA17911 + Undefined + - + + + DQB1*03:272 + HLA17913 + Undefined + - + + + DQB1*03:273 + HLA17915 + Undefined + - + + + DQB1*03:274 + HLA17916 + Undefined + - + + + DQB1*03:275 + HLA18103 + Undefined + - + + + DQB1*03:276N + HLA18123 + NotExpressed + Null + + + DQB1*03:277 + HLA18141 + Undefined + - + + + DQB1*03:278 + HLA18188 + Undefined + - + + + DQB1*03:279 + HLA18285 + Undefined + - + + + DQB1*03:280 + HLA18555 + Undefined + - + + + DQB1*03:281 + HLA18986 + Undefined + - + + + DQB1*03:282N + HLA18988 + NotExpressed + Null + + + DQB1*03:283 + HLA19541 + Undefined + - + + + DQB1*03:284 + HLA19383 + Undefined + - + + + DQB1*03:285 + HLA19340 + Undefined + - + + + DQB1*03:286 + HLA19396 + Undefined + - + + + DQB1*03:287 + HLA19406 + Undefined + - + + + DQB1*03:288 + HLA19374 + Undefined + - + + + DQB1*03:289 + HLA19568 + Undefined + - + + + DQB1*03:290 + HLA19892 + Undefined + - + + + DQB1*03:291 + HLA19821 + Undefined + - + + + DQB1*03:292 + HLA19633 + Undefined + - + + + DQB1*03:293 + HLA19739 + Undefined + - + + + DQB1*03:294 + HLA19930 + Undefined + - + + + DQB1*03:295 + HLA19594 + Undefined + - + + + DQB1*03:296 + HLA19938 + Undefined + - + + + DQB1*03:297 + HLA19630 + Undefined + - + + + DQB1*03:298 + HLA19707 + Undefined + - + + + DQB1*03:299 + HLA21013 + Undefined + - + + + DQB1*03:300 + HLA20865 + Undefined + - + + + DQB1*03:301 + HLA20719 + Undefined + - + + + DQB1*03:302 + HLA21096 + Undefined + - + + + DQB1*03:303N + HLA20602 + NotExpressed + Null + + + DQB1*03:304 + HLA20794 + Undefined + - + + + DQB1*03:305 + HLA20936 + Undefined + - + + + DQB1*03:306 + HLA20691 + Undefined + - + + + DQB1*03:307 + HLA21058 + Undefined + - + + + DQB1*03:308 + HLA20976 + Undefined + - + + + DQB1*03:309:01 + HLA20812 + Undefined + - + + + DQB1*03:309:02 + HLA36112 + Undefined + - + + + DQB1*03:310N + HLA20685 + NotExpressed + Null + + + DQB1*03:311 + HLA20655 + Undefined + - + + + DQB1*03:312 + HLA20871 + Undefined + - + + + DQB1*03:313 + HLA20534 + Undefined + - + + + DQB1*03:314 + HLA20991 + Undefined + - + + + DQB1*03:315 + HLA20846 + Undefined + - + + + DQB1*03:316 + HLA20869 + Undefined + - + + + DQB1*03:317:01 + HLA21158 + Undefined + - + + + DQB1*03:317:02 + HLA20966 + Undefined + - + + + DQB1*03:318 + HLA21136 + Undefined + - + + + DQB1*03:319 + HLA20541 + Undefined + - + + + DQB1*03:320 + HLA20690 + Undefined + - + + + DQB1*03:321 + HLA20761 + Undefined + - + + + DQB1*03:322 + HLA20990 + Undefined + - + + + DQB1*03:323 + HLA20518 + Undefined + - + + + DQB1*03:324 + HLA20598 + Undefined + - + + + DQB1*03:326 + HLA20536 + Undefined + - + + + DQB1*03:327 + HLA20667 + Undefined + - + + + DQB1*03:328 + HLA20704 + Undefined + - + + + DQB1*03:329 + HLA21155 + Undefined + - + + + DQB1*03:330 + HLA20994 + Undefined + - + + + DQB1*03:331 + HLA20858 + Undefined + - + + + DQB1*03:332 + HLA21178 + Undefined + - + + + DQB1*03:333 + HLA21426 + Undefined + - + + + DQB1*03:334N + HLA21493 + NotExpressed + Null + + + DQB1*03:335 + HLA21187 + Undefined + - + + + DQB1*03:336 + HLA21578 + Undefined + - + + + DQB1*03:337 + HLA21526 + Undefined + - + + + DQB1*03:338N + HLA21679 + NotExpressed + Null + + + DQB1*03:339N + HLA21898 + NotExpressed + Null + + + DQB1*03:340N + HLA21744 + NotExpressed + Null + + + DQB1*03:341 + HLA21736 + Undefined + - + + + DQB1*03:342 + HLA21889 + Undefined + - + + + DQB1*03:343 + HLA21677 + Undefined + - + + + DQB1*03:344 + HLA21789 + Undefined + - + + + DQB1*03:345 + HLA21735 + Undefined + - + + + DQB1*03:346 + HLA21721 + Undefined + - + + + DQB1*03:347 + HLA21805 + Undefined + - + + + DQB1*03:348 + HLA21628 + Undefined + - + + + DQB1*03:349 + HLA21907 + Undefined + - + + + DQB1*03:350 + HLA21868 + Undefined + - + + + DQB1*03:351 + HLA21914 + Undefined + - + + + DQB1*03:352 + HLA21913 + Undefined + - + + + DQB1*03:353 + HLA21921 + Undefined + - + + + DQB1*03:354N + HLA22383 + NotExpressed + Null + + + DQB1*03:355 + HLA22286 + Undefined + - + + + DQB1*03:356N + HLA22613 + NotExpressed + Null + + + DQB1*03:357N + HLA22504 + NotExpressed + Null + + + DQB1*03:358N + HLA22213 + NotExpressed + Null + + + DQB1*03:359 + HLA22745 + Undefined + - + + + DQB1*03:360 + HLA22915 + Undefined + - + + + DQB1*03:361 + HLA22968 + Undefined + - + + + DQB1*03:362 + HLA22889 + Undefined + - + + + DQB1*03:363 + HLA23169 + Undefined + - + + + DQB1*03:364 + HLA23720 + Undefined + - + + + DQB1*03:365 + HLA23128 + Undefined + - + + + DQB1*03:366 + HLA23126 + Undefined + - + + + DQB1*03:367 + HLA23311 + Undefined + - + + + DQB1*03:368 + HLA23655 + Undefined + - + + + DQB1*03:369 + HLA23400 + Undefined + - + + + DQB1*03:370 + HLA23384 + Undefined + - + + + DQB1*03:371 + HLA23584 + Undefined + - + + + DQB1*03:372 + HLA23807 + Undefined + - + + + DQB1*03:373 + HLA23366 + Undefined + - + + + DQB1*03:374 + HLA23288 + Undefined + - + + + DQB1*03:375N + HLA23636 + NotExpressed + Null + + + DQB1*03:376N + HLA23287 + NotExpressed + Null + + + DQB1*03:377 + HLA23094 + Undefined + - + + + DQB1*03:378 + HLA23357 + Undefined + - + + + DQB1*03:379 + HLA23171 + Undefined + - + + + DQB1*03:380 + HLA23008 + Undefined + - + + + DQB1*03:381 + HLA23597 + Undefined + - + + + DQB1*03:382:01 + HLA23289 + Undefined + - + + + DQB1*03:382:02 + HLA38242 + Undefined + - + + + DQB1*03:383 + HLA23739 + Undefined + - + + + DQB1*03:384 + HLA23104 + Undefined + - + + + DQB1*03:385N + HLA23713 + NotExpressed + Null + + + DQB1*03:386 + HLA23130 + Undefined + - + + + DQB1*03:387 + HLA23069 + Undefined + - + + + DQB1*03:388 + HLA23728 + Undefined + - + + + DQB1*03:389 + HLA23308 + Undefined + - + + + DQB1*03:390 + HLA23812 + Undefined + - + + + DQB1*03:391 + HLA23240 + Undefined + - + + + DQB1*03:392 + HLA23516 + Undefined + - + + + DQB1*03:393 + HLA24233 + Undefined + - + + + DQB1*03:394 + HLA23924 + Undefined + - + + + DQB1*03:395 + HLA23841 + Undefined + - + + + DQB1*03:396 + HLA23952 + Undefined + - + + + DQB1*03:397 + HLA24001 + Undefined + - + + + DQB1*03:398 + HLA24148 + Undefined + - + + + DQB1*03:399N + HLA24021 + NotExpressed + Null + + + DQB1*03:400N + HLA23936 + NotExpressed + Null + + + DQB1*03:401 + HLA24115 + Undefined + - + + + DQB1*03:402 + HLA24822 + Undefined + - + + + DQB1*03:403N + HLA25272 + NotExpressed + Null + + + DQB1*03:404 + HLA24934 + Undefined + - + + + DQB1*03:405 + HLA25983 + Undefined + - + + + DQB1*03:406 + HLA25648 + Undefined + - + + + DQB1*03:407N + HLA25781 + NotExpressed + Null + + + DQB1*03:408 + HLA25959 + Undefined + - + + + DQB1*03:409 + HLA25946 + Undefined + - + + + DQB1*03:410 + HLA25851 + Undefined + - + + + DQB1*03:411N + HLA26019 + NotExpressed + Null + + + DQB1*03:412 + HLA26089 + Undefined + - + + + DQB1*03:413 + HLA26314 + Undefined + - + + + DQB1*03:414 + HLA26218 + Undefined + - + + + DQB1*03:415 + HLA26392 + Undefined + - + + + DQB1*03:416 + HLA26267 + Undefined + - + + + DQB1*03:417 + HLA26260 + Undefined + - + + + DQB1*03:418 + HLA26564 + Undefined + - + + + DQB1*03:419 + HLA26434 + Undefined + - + + + DQB1*03:420 + HLA26692 + Undefined + - + + + DQB1*03:421 + HLA26862 + Undefined + - + + + DQB1*03:422N + HLA26789 + NotExpressed + Null + + + DQB1*03:423 + HLA26868 + Undefined + - + + + DQB1*03:424 + HLA27212 + Undefined + - + + + DQB1*03:425 + HLA27215 + Undefined + - + + + DQB1*03:426 + HLA27249 + Undefined + - + + + DQB1*03:427N + HLA27501 + NotExpressed + Null + + + DQB1*03:428 + HLA27505 + Undefined + - + + + DQB1*03:429 + HLA27588 + Undefined + - + + + DQB1*03:430 + HLA27605 + Undefined + - + + + DQB1*03:431 + HLA27560 + Undefined + - + + + DQB1*03:432 + HLA28229 + Undefined + - + + + DQB1*03:433 + HLA28336 + Undefined + - + + + DQB1*03:434 + HLA28341 + Undefined + - + + + DQB1*03:435 + HLA28345 + Undefined + - + + + DQB1*03:436 + HLA28348 + Undefined + - + + + DQB1*03:437 + HLA28560 + Undefined + - + + + DQB1*03:438 + HLA28561 + Undefined + - + + + DQB1*03:439 + HLA29020 + Undefined + - + + + DQB1*03:440N + HLA28794 + NotExpressed + Null + + + DQB1*03:441 + HLA28880 + Undefined + - + + + DQB1*03:442 + HLA28807 + Undefined + - + + + DQB1*03:443 + HLA28852 + Undefined + - + + + DQB1*03:444 + HLA29146 + Undefined + - + + + DQB1*03:445 + HLA29151 + Undefined + - + + + DQB1*03:446 + HLA29268 + Undefined + - + + + DQB1*03:447 + HLA29497 + Undefined + - + + + DQB1*03:448 + HLA29397 + Undefined + - + + + DQB1*03:449 + HLA29514 + Undefined + - + + + DQB1*03:450 + HLA29454 + Undefined + - + + + DQB1*03:451 + HLA30254 + Undefined + - + + + DQB1*03:452 + HLA30125 + Undefined + - + + + DQB1*03:453 + HLA30586 + Undefined + - + + + DQB1*03:454 + HLA30508 + Undefined + - + + + DQB1*03:455 + HLA30627 + Undefined + - + + + DQB1*03:456 + HLA30635 + Undefined + - + + + DQB1*03:457 + HLA30771 + Undefined + - + + + DQB1*03:458 + HLA30814 + Undefined + - + + + DQB1*03:459 + HLA31314 + Undefined + - + + + DQB1*03:460 + HLA31287 + Undefined + - + + + DQB1*03:461 + HLA31075 + Undefined + - + + + DQB1*03:462 + HLA31248 + Undefined + - + + + DQB1*03:463 + HLA31076 + Undefined + - + + + DQB1*03:464 + HLA31255 + Undefined + - + + + DQB1*03:465 + HLA31565 + Undefined + - + + + DQB1*03:466 + HLA31795 + Undefined + - + + + DQB1*03:467 + HLA32012 + Undefined + - + + + DQB1*03:468 + HLA32254 + Undefined + - + + + DQB1*03:469 + HLA32181 + Undefined + - + + + DQB1*03:470 + HLA32267 + Undefined + - + + + DQB1*03:471 + HLA33263 + Undefined + - + + + DQB1*03:472 + HLA32748 + Undefined + - + + + DQB1*03:473N + HLA33675 + NotExpressed + Null + + + DQB1*03:474 + HLA33554 + Undefined + - + + + DQB1*03:475 + HLA33586 + Undefined + - + + + DQB1*03:476 + HLA33548 + Undefined + - + + + DQB1*03:477 + HLA33556 + Undefined + - + + + DQB1*03:478 + HLA33524 + Undefined + - + + + DQB1*03:479 + HLA33952 + Undefined + - + + + DQB1*03:480Q + HLA33918 + Undefined + - + + + DQB1*03:481 + HLA34413 + Undefined + - + + + DQB1*03:482 + HLA34375 + Undefined + - + + + DQB1*03:483 + HLA34257 + Undefined + - + + + DQB1*03:484 + HLA34364 + Undefined + - + + + DQB1*03:485 + HLA34398 + Undefined + - + + + DQB1*03:486 + HLA34326 + Undefined + - + + + DQB1*03:487 + HLA34251 + Undefined + - + + + DQB1*03:488N + HLA34525 + NotExpressed + Null + + + DQB1*03:489 + HLA35034 + Undefined + - + + + DQB1*03:490 + HLA35221 + Undefined + - + + + DQB1*03:491 + HLA35235 + Undefined + - + + + DQB1*03:492 + HLA34862 + Undefined + - + + + DQB1*03:493 + HLA34942 + Undefined + - + + + DQB1*03:494 + HLA35393 + Undefined + - + + + DQB1*03:495 + HLA36272 + Undefined + - + + + DQB1*03:496 + HLA36184 + Undefined + - + + + DQB1*03:497 + HLA36140 + Undefined + - + + + DQB1*03:498 + HLA36163 + Undefined + - + + + DQB1*03:499N + HLA36309 + NotExpressed + Null + + + DQB1*03:500 + HLA36197 + Undefined + - + + + DQB1*03:501 + HLA36444 + Undefined + - + + + DQB1*03:502 + HLA36338 + Undefined + - + 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DQB1*04:02:01:01 + HLA00637 + DQ4 + DQ4 + + + DQB1*04:02:01:02 + HLA16167 + DQ4 + DQ4 + + + DQB1*04:02:01:03 + HLA16186 + DQ4 + DQ4 + + + DQB1*04:02:01:04 + HLA17740 + DQ4 + DQ4 + + + DQB1*04:02:01:05 + HLA17741 + DQ4 + DQ4 + + + DQB1*04:02:01:06 + HLA17785 + DQ4 + DQ4 + + + DQB1*04:02:01:07 + HLA17965 + DQ4 + DQ4 + + + DQB1*04:02:01:08 + HLA21385 + DQ4 + DQ4 + + + DQB1*04:02:01:09 + HLA21333 + DQ4 + DQ4 + + + DQB1*04:02:01:10 + HLA21235 + DQ4 + DQ4 + + + DQB1*04:02:01:11 + HLA27801 + DQ4 + DQ4 + + + DQB1*04:02:01:12 + HLA31083 + DQ4 + DQ4 + + + DQB1*04:02:01:13 + HLA32133 + DQ4 + DQ4 + + + DQB1*04:02:01:14 + HLA33699 + DQ4 + DQ4 + + + DQB1*04:02:01:15 + HLA33729 + DQ4 + DQ4 + + + DQB1*04:02:01:16Q + HLA34549 + Undefined + - + + + DQB1*04:02:01:17 + HLA35185 + DQ4 + DQ4 + + + DQB1*04:02:01:18 + HLA35521 + DQ4 + DQ4 + + + DQB1*04:02:01:19 + HLA36250 + DQ4 + DQ4 + + + DQB1*04:02:01:20 + HLA36085 + DQ4 + DQ4 + + + DQB1*04:02:01:21 + HLA38519 + DQ4 + DQ4 + + + DQB1*04:02:02 + HLA05770 + DQ4 + DQ4 + + + DQB1*04:02:03 + HLA09361 + DQ4 + DQ4 + + + DQB1*04:02:04 + HLA09745 + DQ4 + DQ4 + + + DQB1*04:02:05 + HLA10235 + DQ4 + DQ4 + + + DQB1*04:02:06 + HLA11364 + DQ4 + DQ4 + + + DQB1*04:02:07 + HLA12048 + DQ4 + DQ4 + + + DQB1*04:02:08 + HLA12049 + DQ4 + DQ4 + + + DQB1*04:02:09 + HLA13148 + DQ4 + DQ4 + + + DQB1*04:02:10 + HLA13933 + DQ4 + DQ4 + + + DQB1*04:02:11 + HLA16147 + DQ4 + DQ4 + + + DQB1*04:02:12 + HLA16185 + DQ4 + DQ4 + + + DQB1*04:02:13 + HLA17165 + DQ4 + DQ4 + + + DQB1*04:02:14 + HLA17426 + DQ4 + DQ4 + + + DQB1*04:02:15 + HLA18644 + DQ4 + DQ4 + + + DQB1*04:02:16 + HLA18811 + DQ4 + DQ4 + + + DQB1*04:02:17 + HLA20803 + DQ4 + DQ4 + + + DQB1*04:02:18 + HLA21608 + DQ4 + DQ4 + + + DQB1*04:02:19 + HLA23545 + DQ4 + DQ4 + + + DQB1*04:02:20 + HLA25589 + DQ4 + DQ4 + + + DQB1*04:02:21 + HLA29534 + DQ4 + DQ4 + + + DQB1*04:02:22 + HLA32798 + DQ4 + DQ4 + + + DQB1*04:02:23 + HLA36340 + DQ4 + DQ4 + + + DQB1*04:02:24 + HLA36727 + DQ4 + DQ4 + + + DQB1*04:03:01 + HLA03234 + Undefined + - + + + DQB1*04:03:02 + HLA04125 + Undefined + - + + + DQB1*04:03:03 + HLA17444 + Undefined + - + + + DQB1*04:04 + HLA04390 + Undefined + - + + + DQB1*04:05 + HLA05136 + Undefined + - + + + DQB1*04:06 + HLA05765 + Undefined + - + + + DQB1*04:07 + HLA06146 + Undefined + - + + + DQB1*04:08 + HLA06178 + Undefined + - + + + DQB1*04:09 + HLA09075 + Undefined + - + + + DQB1*04:10 + HLA09137 + Undefined + - + + + DQB1*04:11 + HLA09359 + Undefined + - + + + DQB1*04:12 + HLA09362 + Undefined + - + + + DQB1*04:13 + HLA09652 + Undefined + - + + + DQB1*04:14 + HLA09859 + Undefined + - + + + DQB1*04:15 + HLA09861 + Undefined + - + + + DQB1*04:16 + HLA09863 + Undefined + - + + + DQB1*04:17 + HLA09865 + Undefined + - + + + DQB1*04:18 + HLA10294 + Undefined + - + + + DQB1*04:19 + HLA10932 + Undefined + - + + + DQB1*04:20 + HLA11362 + Undefined + - + + + DQB1*04:21 + HLA11363 + Undefined + - + + + DQB1*04:22 + HLA11365 + Undefined + - + + + DQB1*04:23 + HLA12158 + Undefined + - + + + DQB1*04:24 + HLA12532 + Undefined + - + + + DQB1*04:25N + HLA12533 + NotExpressed + Null + + + DQB1*04:26 + HLA12802 + Undefined + - + + + DQB1*04:27 + HLA12803 + Undefined + - + + + DQB1*04:28 + HLA13146 + Undefined + - + + + DQB1*04:29 + HLA13147 + Undefined + - + + + DQB1*04:30 + HLA13939 + Undefined + - + + + DQB1*04:31 + HLA14042 + Undefined + - + + + DQB1*04:32 + HLA13982 + Undefined + - + + + DQB1*04:33 + HLA14350 + Undefined + - + + + DQB1*04:34 + HLA14763 + Undefined + - + + + DQB1*04:35 + HLA15326 + Undefined + - + + + DQB1*04:36N + HLA15327 + NotExpressed + Null + + + DQB1*04:37 + HLA15483 + Undefined + - + + + DQB1*04:38 + HLA15691 + Undefined + - + + + DQB1*04:39 + HLA16318 + Undefined + - + + + DQB1*04:40 + HLA16960 + Undefined + - + + + DQB1*04:41N + HLA17403 + NotExpressed + Null + + + DQB1*04:42 + HLA17643 + Undefined + - + + + DQB1*04:43 + HLA18646 + Undefined + - + + + DQB1*04:44 + HLA18690 + Undefined + - + + + DQB1*04:45 + HLA18702 + Undefined + - + + + DQB1*04:46N + HLA18801 + NotExpressed + Null + + + DQB1*04:47 + HLA18808 + Undefined + - + + + DQB1*04:48 + HLA18810 + Undefined + - + + + DQB1*04:49 + HLA18814 + Undefined + - + + + DQB1*04:50 + HLA18960 + Undefined + - + + + DQB1*04:51 + HLA19662 + Undefined + - + + + DQB1*04:52 + HLA19910 + Undefined + - + + + DQB1*04:53 + HLA20844 + Undefined + - + + + DQB1*04:54 + HLA21124 + Undefined + - + + + DQB1*04:55 + HLA20587 + Undefined + - + + + DQB1*04:56 + HLA20637 + Undefined + - + + + DQB1*04:57 + HLA20757 + Undefined + - + + + DQB1*04:58 + HLA21798 + Undefined + - + + + DQB1*04:59N + HLA21633 + NotExpressed + Null + + + DQB1*04:60 + HLA21719 + Undefined + - + + + DQB1*04:61 + HLA21922 + Undefined + - + + + DQB1*04:62 + HLA22520 + Undefined + - + + + DQB1*04:63 + HLA22827 + Undefined + - + + + DQB1*04:64 + HLA23377 + Undefined + - + + + DQB1*04:65 + HLA23110 + Undefined + - + + + DQB1*04:66 + HLA23344 + Undefined + - + + + DQB1*04:67 + HLA23746 + Undefined + - + + + DQB1*04:68N + HLA23520 + NotExpressed + Null + + + DQB1*04:69 + HLA23200 + Undefined + - + + + DQB1*04:70 + HLA23358 + Undefined + - + + + DQB1*04:71 + HLA23939 + Undefined + - + + + DQB1*04:72 + HLA24147 + Undefined + - + + + DQB1*04:73N + HLA24189 + NotExpressed + Null + + + DQB1*04:74 + HLA25478 + Undefined + - + + + DQB1*04:75 + HLA25918 + Undefined + - + + + DQB1*04:76 + HLA26180 + Undefined + - + + + DQB1*04:77 + HLA26139 + Undefined + - + + + DQB1*04:78 + HLA27610 + Undefined + - + + + DQB1*04:79 + HLA27918 + Undefined + - + + + DQB1*04:80 + HLA28338 + Undefined + - + + + DQB1*04:81 + HLA28340 + Undefined + - + + + DQB1*04:82 + HLA28342 + Undefined + - + + + DQB1*04:83 + HLA28343 + Undefined + - + + + DQB1*04:84 + HLA28818 + Undefined + - + + + DQB1*04:85 + HLA29285 + Undefined + - + + + DQB1*04:86 + HLA29640 + Undefined + - + + + DQB1*04:87 + HLA32159 + Undefined + - + + + DQB1*04:88 + HLA33519 + Undefined + - + + + DQB1*04:89 + HLA33576 + Undefined + - + + + DQB1*04:90 + HLA33638 + Undefined + - + + + DQB1*04:91 + HLA34267 + Undefined + - + + + DQB1*04:92 + HLA35194 + Undefined + - + + + DQB1*04:93 + HLA36260 + Undefined + - + + + DQB1*04:94 + HLA36275 + Undefined + - + + + DQB1*04:95 + HLA36504 + Undefined + - + + + DQB1*04:96 + HLA37044 + Undefined + - + + + DQB1*04:97 + HLA37756 + Undefined + - + + + DQB1*05:01:01:01 + HLA00638 + DQ5 + DQ5(1) + + + DQB1*05:01:01:02 + HLA06615 + DQ5 + DQ5(1) + + + DQB1*05:01:01:03 + HLA12879 + DQ5 + DQ5(1) + + + DQB1*05:01:01:04 + HLA17161 + DQ5 + DQ5(1) + + + DQB1*05:01:01:05 + HLA17371 + DQ5 + DQ5(1) + + + DQB1*05:01:01:06 + HLA26124 + DQ5 + DQ5(1) + + + DQB1*05:01:01:07 + HLA26224 + DQ5 + DQ5(1) + + + DQB1*05:01:01:08 + HLA26984 + DQ5 + DQ5(1) + + + DQB1*05:01:01:09 + HLA28238 + DQ5 + DQ5(1) + + + DQB1*05:01:01:10 + HLA28719 + DQ5 + DQ5(1) + + + DQB1*05:01:01:11 + HLA29223 + DQ5 + DQ5(1) + + + DQB1*05:01:01:12 + HLA29219 + DQ5 + DQ5(1) + + + DQB1*05:01:01:13 + HLA29389 + DQ5 + DQ5(1) + + + DQB1*05:01:01:14 + HLA31841 + DQ5 + DQ5(1) + + + DQB1*05:01:01:15 + HLA31854 + DQ5 + DQ5(1) + + + DQB1*05:01:01:16 + HLA31911 + DQ5 + DQ5(1) + + + DQB1*05:01:01:17 + HLA32145 + DQ5 + DQ5(1) + + + DQB1*05:01:01:18 + HLA31878 + DQ5 + DQ5(1) + + + DQB1*05:01:01:19 + HLA33719 + DQ5 + DQ5(1) + + + DQB1*05:01:01:20 + HLA33740 + DQ5 + DQ5(1) + + + DQB1*05:01:01:21 + HLA33806 + DQ5 + DQ5(1) + + + DQB1*05:01:01:22 + HLA33802 + DQ5 + DQ5(1) + + + DQB1*05:01:01:23 + HLA33701 + DQ5 + DQ5(1) + + + DQB1*05:01:01:24 + HLA33703 + DQ5 + DQ5(1) + + + DQB1*05:01:01:25 + HLA34715 + DQ5 + DQ5(1) + + + DQB1*05:01:01:26 + HLA34930 + DQ5 + DQ5(1) + + + DQB1*05:01:01:27 + HLA35431 + DQ5 + DQ5(1) + + + DQB1*05:01:01:28 + HLA36497 + DQ5 + DQ5(1) + + + DQB1*05:01:01:29 + HLA36393 + DQ5 + DQ5(1) + + + DQB1*05:01:01:30 + HLA36401 + DQ5 + DQ5(1) + + + DQB1*05:01:01:31 + HLA37203 + DQ5 + DQ5(1) + + + DQB1*05:01:01:32 + HLA38268 + DQ5 + DQ5(1) + + + DQB1*05:01:01:33 + HLA38722 + DQ5 + DQ5(1) + + + DQB1*05:01:01:34 + HLA38536 + DQ5 + DQ5(1) + + + DQB1*05:01:02 + HLA01086 + DQ5 + DQ5(1) 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DQB1*05:01:45 + HLA32283 + DQ5 + DQ5(1) + + + DQB1*05:01:46 + HLA34476 + DQ5 + DQ5(1) + + + DQB1*05:01:47 + HLA35508 + DQ5 + DQ5(1) + + + DQB1*05:01:48 + HLA36804 + DQ5 + DQ5(1) + + + DQB1*05:02:01:01 + HLA00639 + DQ5 + DQ5(1) + + + DQB1*05:02:01:02 + HLA17372 + DQ5 + DQ5(1) + + + DQB1*05:02:01:03 + HLA17373 + DQ5 + DQ5(1) + + + DQB1*05:02:01:04 + HLA19234 + DQ5 + DQ5(1) + + + DQB1*05:02:01:05 + HLA22477 + DQ5 + DQ5(1) + + + DQB1*05:02:01:06 + HLA22739 + DQ5 + DQ5(1) + + + DQB1*05:02:01:07 + HLA26985 + DQ5 + DQ5(1) + + + DQB1*05:02:01:08 + HLA28468 + DQ5 + DQ5(1) + + + DQB1*05:02:01:09 + HLA30799 + DQ5 + DQ5(1) + + + DQB1*05:02:01:10 + HLA31880 + DQ5 + DQ5(1) + + + DQB1*05:02:01:11 + HLA31894 + DQ5 + DQ5(1) + + + DQB1*05:02:01:12 + HLA33490 + DQ5 + DQ5(1) + + + DQB1*05:02:01:13 + HLA36043 + DQ5 + DQ5(1) + + + DQB1*05:02:01:14 + HLA36928 + DQ5 + DQ5(1) + + + DQB1*05:02:01:15 + HLA36907 + DQ5 + DQ5(1) + + + DQB1*05:02:02 + HLA01573 + DQ5 + DQ5(1) + + + DQB1*05:02:03 + HLA05766 + DQ5 + DQ5(1) + + + DQB1*05:02:04 + HLA09348 + DQ5 + DQ5(1) + + + DQB1*05:02:05 + HLA09830 + DQ5 + DQ5(1) + + + DQB1*05:02:06 + HLA09832 + DQ5 + DQ5(1) + + + DQB1*05:02:07 + HLA09843 + DQ5 + DQ5(1) + + + DQB1*05:02:08 + HLA10632 + DQ5 + DQ5(1) + + + DQB1*05:02:09 + HLA11597 + DQ5 + DQ5(1) + + + DQB1*05:02:10 + HLA12033 + DQ5 + DQ5(1) + + + DQB1*05:02:11 + HLA12699 + DQ5 + DQ5(1) + + + DQB1*05:02:12 + HLA12915 + DQ5 + DQ5(1) + + + DQB1*05:02:13 + HLA13145 + DQ5 + DQ5(1) + + + DQB1*05:02:14 + HLA18151 + DQ5 + DQ5(1) + + + DQB1*05:02:15 + HLA18954 + DQ5 + DQ5(1) + + + DQB1*05:02:16 + HLA19625 + DQ5 + DQ5(1) + + + DQB1*05:02:17 + HLA19751 + DQ5 + DQ5(1) + + + DQB1*05:02:18 + HLA20512 + DQ5 + DQ5(1) + + + DQB1*05:02:19 + HLA21778 + DQ5 + DQ5(1) + + + DQB1*05:02:20 + HLA23774 + DQ5 + DQ5(1) + + + DQB1*05:02:21 + HLA23383 + DQ5 + DQ5(1) + + + DQB1*05:02:22 + HLA23215 + DQ5 + DQ5(1) + + + DQB1*05:02:23 + HLA26704 + DQ5 + DQ5(1) + + + DQB1*05:02:24 + HLA29007 + DQ5 + DQ5(1) + + + DQB1*05:02:25 + HLA29351 + DQ5 + DQ5(1) + + + DQB1*05:02:26 + HLA32166 + DQ5 + DQ5(1) + + + DQB1*05:02:27 + HLA36096 + DQ5 + DQ5(1) + + + DQB1*05:02:28 + HLA38542 + DQ5 + DQ5(1) + + + DQB1*05:03:01:01 + HLA00640 + DQ5 + DQ5(1) + + + DQB1*05:03:01:02 + HLA06622 + DQ5 + DQ5(1) + + + DQB1*05:03:01:03 + HLA17200 + DQ5 + DQ5(1) + + + DQB1*05:03:01:04 + HLA23976 + DQ5 + DQ5(1) + + + DQB1*05:03:01:05 + HLA27800 + DQ5 + DQ5(1) + + + DQB1*05:03:01:06 + HLA30802 + DQ5 + DQ5(1) + + + DQB1*05:03:01:07 + HLA30596 + DQ5 + DQ5(1) + + + DQB1*05:03:01:08 + HLA33753 + DQ5 + DQ5(1) + + + DQB1*05:03:01:09 + HLA36566 + DQ5 + DQ5(1) + + + DQB1*05:03:01:10 + HLA37532 + DQ5 + DQ5(1) + + + DQB1*05:03:02 + HLA00641 + DQ5 + DQ5(1) + + + DQB1*05:03:03 + HLA05769 + DQ5 + DQ5(1) + + + DQB1*05:03:04 + HLA06120 + DQ5 + DQ5(1) + + + DQB1*05:03:05 + HLA06823 + DQ5 + DQ5(1) + + + DQB1*05:03:06 + HLA09349 + DQ5 + DQ5(1) + + + DQB1*05:03:07 + HLA09350 + DQ5 + DQ5(1) + + + DQB1*05:03:08 + HLA09744 + DQ5 + DQ5(1) + + + DQB1*05:03:09 + HLA09876 + DQ5 + DQ5(1) + + + DQB1*05:03:10 + HLA09851 + DQ5 + DQ5(1) + + + DQB1*05:03:11 + HLA10553 + DQ5 + DQ5(1) + + + DQB1*05:03:12 + HLA11146 + DQ5 + DQ5(1) + + + DQB1*05:03:13 + HLA11148 + DQ5 + DQ5(1) + + + DQB1*05:03:14 + HLA11594 + DQ5 + DQ5(1) + + + DQB1*05:03:15 + HLA11888 + DQ5 + DQ5(1) + + + DQB1*05:03:16 + HLA11890 + DQ5 + DQ5(1) + + + DQB1*05:03:17 + HLA13193 + DQ5 + DQ5(1) + + + DQB1*05:03:18 + HLA19726 + DQ5 + DQ5(1) + + + DQB1*05:03:19 + HLA19682 + DQ5 + DQ5(1) + + + DQB1*05:03:20 + HLA21393 + DQ5 + DQ5(1) + + + DQB1*05:03:21 + HLA23982 + DQ5 + DQ5(1) + + + DQB1*05:03:22 + HLA24245 + DQ5 + DQ5(1) + + + DQB1*05:03:23 + HLA26204 + DQ5 + DQ5(1) + + + DQB1*05:03:24 + HLA28878 + DQ5 + DQ5(1) + + + DQB1*05:03:25 + HLA28815 + DQ5 + DQ5(1) + + + DQB1*05:03:26 + HLA29817 + DQ5 + DQ5(1) + + + DQB1*05:03:27 + HLA29887 + DQ5 + DQ5(1) + + + DQB1*05:03:28 + HLA32640 + DQ5 + DQ5(1) + + + DQB1*05:03:29 + HLA35110 + DQ5 + DQ5(1) + + + DQB1*05:03:30 + HLA34822 + DQ5 + DQ5(1) + + + DQB1*05:03:31 + HLA38557 + DQ5 + DQ5(1) + + + DQB1*05:04 + HLA00642 + DQ5 + DQ5(1) + + + DQB1*05:05:01 + HLA02689 + DQ5 + - + + + DQB1*05:05:02 + HLA09856 + DQ5 + - + + + DQB1*05:06:01 + HLA05383 + Undefined + - + + + DQB1*05:06:02 + HLA11592 + Undefined + - + + + DQB1*05:07 + HLA05772 + Undefined + - + + + DQB1*05:08 + HLA05775 + Undefined + - + + + DQB1*05:09 + HLA06034 + Undefined + - + + + DQB1*05:10 + HLA06035 + Undefined + - + + + DQB1*05:11:01 + HLA06287 + Undefined + - + + + DQB1*05:11:02 + HLA10288 + Undefined + - + + + DQB1*05:12 + HLA06670 + Undefined + - + + + DQB1*05:13 + HLA07091 + Undefined + - + + + DQB1*05:14 + HLA07330 + Undefined + - + + + DQB1*05:15 + HLA07929 + Undefined + - + + + DQB1*05:16 + HLA08292 + Undefined + - + + + DQB1*05:17 + HLA08596 + Undefined + - + + + DQB1*05:18:01 + HLA08605 + Undefined + - + + + DQB1*05:18:02 + HLA28467 + Undefined + - + + + DQB1*05:19 + HLA09102 + Undefined + - + + + DQB1*05:20:01 + HLA09291 + Undefined + - + + + DQB1*05:20:02 + HLA31317 + Undefined + - + + + DQB1*05:21 + HLA09292 + Undefined + - + + + DQB1*05:22 + HLA09294 + Undefined + - + + + DQB1*05:23 + HLA09351 + Undefined + - + + + DQB1*05:24 + HLA09352 + Undefined + - + + + DQB1*05:25 + HLA09353 + Undefined + - + + + DQB1*05:26 + HLA09354 + Undefined + - + + + DQB1*05:27 + HLA09509 + Undefined + - + + + DQB1*05:28 + HLA09743 + Undefined + - + + + DQB1*05:29 + HLA09826 + Undefined + - + + + DQB1*05:30 + HLA09869 + Undefined + - + + + DQB1*05:31 + HLA09828 + Undefined + - + + + DQB1*05:32 + HLA09829 + Undefined + - + + + DQB1*05:33 + HLA09835 + Undefined + - + + + DQB1*05:34 + HLA09836 + Undefined + - + + + DQB1*05:35 + HLA09838 + Undefined + - + + + DQB1*05:36 + HLA09839 + Undefined + - + + + DQB1*05:37 + HLA09841 + Undefined + - + + + DQB1*05:38 + HLA09845 + Undefined + - + + + DQB1*05:39 + HLA09847 + Undefined + - + + + DQB1*05:40 + HLA09849 + Undefined + - + + + DQB1*05:41N + HLA09853 + NotExpressed + Null + + + DQB1*05:42 + HLA09855 + Undefined + - + + + DQB1*05:43:01 + HLA09833 + Undefined + - + + + DQB1*05:43:02 + HLA16144 + Undefined + - + + + DQB1*05:44 + HLA10112 + Undefined + - + + + DQB1*05:45 + HLA10236 + Undefined + - + + + DQB1*05:46 + HLA10238 + Undefined + - + + + DQB1*05:47 + HLA10239 + Undefined + - + + + DQB1*05:48 + HLA10289 + Undefined + - + + + DQB1*05:49 + HLA10290 + Undefined + - + + + DQB1*05:50 + HLA10476 + Undefined + - + + + DQB1*05:51 + HLA10544 + Undefined + - + + + DQB1*05:52 + HLA10549 + Undefined + - + + + DQB1*05:53 + HLA10550 + Undefined + - + + + DQB1*05:54 + HLA10551 + Undefined + - + + + DQB1*05:55 + HLA10552 + Undefined + - + + + DQB1*05:56 + HLA10864 + Undefined + - + + + DQB1*05:57 + HLA11080 + Undefined + - + + + DQB1*05:58 + HLA11147 + Undefined + - + + + DQB1*05:59 + HLA11149 + Undefined + - + + + DQB1*05:60 + HLA11557 + Undefined + - + + + DQB1*05:61 + HLA11150 + Undefined + - + + + DQB1*05:62 + HLA11157 + Undefined + - + + + DQB1*05:63 + HLA11283 + Undefined + - + + + DQB1*05:64 + HLA11284 + Undefined + - + + + DQB1*05:65 + HLA11285 + Undefined + - + + + DQB1*05:66:01 + HLA11359 + Undefined + - + + + DQB1*05:66:02 + HLA14215 + Undefined + - + + + DQB1*05:67 + HLA11361 + Undefined + - + + + DQB1*05:68 + HLA11593 + Undefined + - + + + DQB1*05:69 + HLA11595 + Undefined + - + + + DQB1*05:70 + HLA11680 + Undefined + - + + + DQB1*05:71 + HLA11681 + Undefined + - + + + DQB1*05:72 + HLA11682 + Undefined + - + + + DQB1*05:73 + HLA11683 + Undefined + - + + + DQB1*05:74 + HLA11889 + Undefined + - + + + DQB1*05:75 + HLA12032 + Undefined + - + + + DQB1*05:76 + HLA12034 + Undefined + - + + + DQB1*05:77 + HLA12045 + Undefined + - + + + DQB1*05:78 + HLA12160 + Undefined + - + + + DQB1*05:79 + HLA12204 + Undefined + - + + + DQB1*05:80 + HLA12212 + Undefined + - + + + DQB1*05:81 + HLA12213 + Undefined + - + + + DQB1*05:82 + HLA12357 + Undefined + - + + + DQB1*05:83 + HLA12358 + Undefined + - + + + DQB1*05:84 + HLA12403 + Undefined + - + + + DQB1*05:85 + HLA12530 + Undefined + - + + + DQB1*05:86 + HLA12531 + Undefined + - + + + DQB1*05:87Q + HLA12585 + Undefined + - + + + DQB1*05:88 + HLA12801 + Undefined + - + + + DQB1*05:89:01 + HLA12871 + Undefined + - + + + DQB1*05:89:02 + HLA14347 + Undefined + - + + + DQB1*05:90N + HLA12899 + NotExpressed + Null + + + DQB1*05:91 + HLA13143 + Undefined + - + + + DQB1*05:92 + HLA13144 + Undefined + - + + + DQB1*05:93 + HLA13577 + Undefined + - + + + DQB1*05:94 + HLA13582 + Undefined + - + + + DQB1*05:95 + HLA13683 + Undefined + - + + + DQB1*05:96 + HLA13710 + Undefined + - + + + DQB1*05:97 + HLA13811 + Undefined + - + + + DQB1*05:98 + HLA13812 + Undefined + - + + + DQB1*05:99 + HLA13883 + Undefined + - + + + DQB1*05:100 + HLA13884 + Undefined + - + + + DQB1*05:101 + HLA13885 + Undefined + - + + + DQB1*05:102 + HLA13915 + Undefined + - + + + DQB1*05:103 + HLA13921 + Undefined + - + + + DQB1*05:104 + HLA13928 + Undefined + - + + + DQB1*05:105 + HLA13935 + Undefined + - + + + DQB1*05:106 + HLA13937 + Undefined + - + + + DQB1*05:107 + HLA13941 + Undefined + - + + + DQB1*05:108 + HLA13942 + Undefined + - + + + DQB1*05:109 + HLA14041 + Undefined + - + + + DQB1*05:110N + HLA14348 + NotExpressed + Null + + + DQB1*05:111 + HLA14349 + Undefined + - + + + DQB1*05:112 + HLA14546 + Undefined + - + + + DQB1*05:113 + HLA14551 + Undefined + - + + + DQB1*05:114 + HLA14552 + Undefined + - + + + DQB1*05:115 + HLA14553 + Undefined + - + + + DQB1*05:116 + HLA14554 + Undefined + - + + + DQB1*05:117 + HLA14555 + Undefined + - + + + DQB1*05:118 + HLA14556 + Undefined + - + + + DQB1*05:119 + HLA14557 + Undefined + - + + + DQB1*05:120 + HLA15317 + Undefined + - + + + DQB1*05:121 + HLA15319 + Undefined + - + + + DQB1*05:122 + HLA15320 + Undefined + - + + + DQB1*05:123 + HLA15325 + Undefined + - + + + DQB1*05:124 + HLA15482 + Undefined + - + + + DQB1*05:125 + HLA15682 + Undefined + - + + + DQB1*05:126 + HLA15687 + Undefined + - + + + DQB1*05:127 + HLA15688 + Undefined + - + + + DQB1*05:128N + HLA15689 + NotExpressed + Null + + + DQB1*05:129 + HLA15690 + Undefined + - + + + DQB1*05:130 + HLA15747 + Undefined + - + + + DQB1*05:131 + HLA15880 + Undefined + - + + + DQB1*05:132Q + HLA16014 + Undefined + - + + + DQB1*05:133 + HLA16053 + Undefined + - + + + DQB1*05:134 + HLA16138 + Undefined + - + + + DQB1*05:135 + HLA16142 + Undefined + - + + + DQB1*05:136 + HLA16152 + Undefined + - + + + DQB1*05:137 + HLA16161 + Undefined + - + + + DQB1*05:138 + HLA16347 + Undefined + - + + + DQB1*05:139 + HLA16409 + Undefined + - + + + DQB1*05:140 + HLA16566 + Undefined + - + + + DQB1*05:141 + HLA16567 + Undefined + - + + + DQB1*05:142 + HLA16568 + Undefined + - + + + DQB1*05:143 + HLA16625 + Undefined + - + + + DQB1*05:144 + HLA16645 + Undefined + - + + + DQB1*05:145 + HLA16779 + Undefined + - + + + DQB1*05:146 + HLA16780 + Undefined + - + + + DQB1*05:147 + HLA16959 + Undefined + - + + + DQB1*05:148 + HLA17199 + Undefined + - + + + DQB1*05:149 + HLA17295 + Undefined + - + + + DQB1*05:150 + HLA17296 + Undefined + - + + + DQB1*05:151 + HLA17327 + Undefined + - + + + DQB1*05:152 + HLA17344 + Undefined + - + + + DQB1*05:153 + HLA17427 + Undefined + - + + + DQB1*05:154 + HLA17525 + Undefined + - + + + DQB1*05:155 + HLA17577 + Undefined + - + + + DQB1*05:156 + HLA17904 + Undefined + - + + + DQB1*05:157 + HLA17910 + Undefined + - + + + DQB1*05:158 + HLA17917 + Undefined + - + + + DQB1*05:159 + HLA18240 + Undefined + - + + + DQB1*05:160 + HLA18586 + Undefined + - + + + DQB1*05:161 + HLA18955 + Undefined + - + + + DQB1*05:162 + HLA19553 + Undefined + - + + + DQB1*05:163 + HLA19451 + Undefined + - + + + DQB1*05:164 + HLA19886 + Undefined + - + + + DQB1*05:165 + HLA19716 + Undefined + - + + + DQB1*05:166 + HLA19818 + Undefined + - + + + DQB1*05:167 + HLA21108 + Undefined + - + + + DQB1*05:168 + HLA20665 + Undefined + - + + + DQB1*05:169 + HLA20878 + Undefined + - + + + DQB1*05:170 + HLA20875 + Undefined + - + + + DQB1*05:171 + HLA20992 + Undefined + - + + + DQB1*05:172 + HLA20530 + Undefined + - + + + DQB1*05:173 + HLA21026 + Undefined + - + + + DQB1*05:174 + HLA21089 + Undefined + - + + + DQB1*05:175 + HLA20535 + Undefined + - + + + DQB1*05:176 + HLA20995 + Undefined + - + + + DQB1*05:177 + HLA20914 + Undefined + - + + + DQB1*05:178 + HLA20791 + Undefined + - + + + DQB1*05:179 + HLA20769 + Undefined + - + + + DQB1*05:180 + HLA20647 + Undefined + - + + + DQB1*05:181 + HLA20746 + Undefined + - + + + DQB1*05:182 + HLA21107 + Undefined + - + + + DQB1*05:183 + HLA20821 + Undefined + - + + + DQB1*05:184 + HLA20996 + Undefined + - + + + DQB1*05:185N + HLA20998 + NotExpressed + Null + + + DQB1*05:186 + HLA20932 + Undefined + - + + + DQB1*05:187 + HLA21335 + Undefined + - + + + DQB1*05:188 + HLA21212 + Undefined + - + + + DQB1*05:189 + HLA21370 + Undefined + - + + + DQB1*05:190 + HLA21576 + Undefined + - + + + DQB1*05:191 + HLA21267 + Undefined + - + + + DQB1*05:192 + HLA21822 + Undefined + - + + + DQB1*05:193 + HLA21636 + Undefined + - + + + DQB1*05:194 + HLA21630 + Undefined + - + + + DQB1*05:195 + HLA21845 + Undefined + - + + + DQB1*05:196 + HLA21757 + Undefined + - + + + DQB1*05:197 + HLA21664 + Undefined + - + + + DQB1*05:198 + HLA21864 + Undefined + - + + + DQB1*05:199 + HLA21823 + Undefined + - + + + DQB1*05:200 + HLA22111 + Undefined + - + + + DQB1*05:201 + HLA22064 + Undefined + - + + + DQB1*05:202 + HLA22095 + Undefined + - + + + DQB1*05:203 + HLA22071 + Undefined + - + + + DQB1*05:204 + HLA22454 + Undefined + - + + + DQB1*05:205 + HLA22628 + Undefined + - + + + DQB1*05:206N + HLA22557 + NotExpressed + Null + + + DQB1*05:207 + HLA22563 + Undefined + - + + + DQB1*05:208N + HLA22389 + NotExpressed + Null + + + DQB1*05:209 + HLA22231 + Undefined + - + + + DQB1*05:210 + HLA22637 + Undefined + - + + + DQB1*05:211 + HLA22595 + Undefined + - + + + DQB1*05:212 + HLA22554 + Undefined + - + + + DQB1*05:213 + HLA22250 + Undefined + - + + + DQB1*05:214 + HLA22293 + Undefined + - + + + DQB1*05:215N + HLA22405 + NotExpressed + Null + + + DQB1*05:216 + HLA22392 + Undefined + - + + + DQB1*05:217 + HLA22607 + Undefined + - + + + DQB1*05:218 + HLA23282 + Undefined + - + + + DQB1*05:219 + HLA23761 + Undefined + - + + + DQB1*05:220 + HLA23016 + Undefined + - + + + DQB1*05:221 + HLA23281 + Undefined + - + + + DQB1*05:222 + HLA23279 + Undefined + - + + + DQB1*05:223 + HLA23721 + Undefined + - + + + DQB1*05:224N + HLA23039 + NotExpressed + Null + + + DQB1*05:225 + HLA23559 + Undefined + - + + + DQB1*05:226 + HLA23280 + Undefined + - + + + DQB1*05:227 + HLA23421 + Undefined + - + + + DQB1*05:228 + HLA23083 + Undefined + - + + + DQB1*05:229 + HLA23006 + Undefined + - + + + DQB1*05:230 + HLA23638 + Undefined + - + + + DQB1*05:231 + HLA23534 + Undefined + - + + + DQB1*05:232 + HLA24188 + Undefined + - + + + DQB1*05:233 + HLA24193 + Undefined + - + + + DQB1*05:234 + HLA24288 + Undefined + - + + + DQB1*05:235N + HLA24213 + NotExpressed + Null + + + DQB1*05:236N + HLA23835 + NotExpressed + Null + + + DQB1*05:237 + HLA23870 + Undefined + - + + + DQB1*05:238 + HLA24454 + Undefined + - + + + DQB1*05:239 + HLA25811 + Undefined + - + + + DQB1*05:240 + HLA25864 + Undefined + - + + + DQB1*05:241 + HLA25923 + Undefined + - + + + DQB1*05:242 + HLA25833 + Undefined + - + + + DQB1*05:243 + HLA26214 + Undefined + - + + + DQB1*05:244 + HLA26323 + Undefined + - + + + DQB1*05:245 + HLA26357 + Undefined + - + + + DQB1*05:246 + HLA26788 + Undefined + - + + + DQB1*05:247 + HLA27278 + Undefined + - + + + DQB1*05:248 + HLA27507 + Undefined + - + + + DQB1*05:249 + HLA27619 + Undefined + - + + + DQB1*05:250 + HLA28033 + Undefined + - + + + DQB1*05:251 + HLA28195 + Undefined + - + + + DQB1*05:252 + HLA28199 + Undefined + - + + + DQB1*05:253 + HLA28201 + Undefined + - + + + DQB1*05:254 + HLA28240 + Undefined + - + + + DQB1*05:255 + HLA28337 + Undefined + - + + + DQB1*05:256 + HLA28339 + Undefined + - + + + DQB1*05:257 + HLA28422 + Undefined + - + + + DQB1*05:258 + HLA28438 + Undefined + - + + + DQB1*05:259 + HLA28554 + Undefined + - + + + DQB1*05:260 + HLA28556 + Undefined + - + + + DQB1*05:261 + HLA28558 + Undefined + - + + + DQB1*05:262 + HLA28675 + Undefined + - + + + DQB1*05:263 + HLA28595 + Undefined + - + + + DQB1*05:264 + HLA28858 + Undefined + - + + + DQB1*05:265N + HLA28879 + NotExpressed + Null + + + DQB1*05:266 + HLA28825 + Undefined + - + + + DQB1*05:267 + HLA28811 + Undefined + - + + + DQB1*05:268 + HLA28814 + Undefined + - + + + DQB1*05:269 + HLA28816 + Undefined + - + + + DQB1*05:270 + HLA28919 + Undefined + - + + + DQB1*05:271 + HLA29027 + Undefined + - + + + DQB1*05:272 + HLA29145 + Undefined + - + + + DQB1*05:273N + HLA29147 + NotExpressed + Null + + + DQB1*05:274 + HLA29557 + Undefined + - + + + DQB1*05:275 + HLA29873 + Undefined + - + + + DQB1*05:276 + HLA29879 + Undefined + - + + + DQB1*05:277 + HLA30813 + Undefined + - + + + DQB1*05:278 + HLA30963 + Undefined + - + + + DQB1*05:279 + HLA30964 + Undefined + - + + + DQB1*05:280 + HLA31079 + Undefined + - + + + DQB1*05:281 + HLA31120 + Undefined + - + + + DQB1*05:282 + HLA30935 + Undefined + - + + + DQB1*05:283N + HLA32150 + NotExpressed + Null + + + DQB1*05:284 + HLA32240 + Undefined + - + + + DQB1*05:285 + HLA32245 + Undefined + - + + + DQB1*05:286 + HLA32255 + Undefined + - + + + DQB1*05:287 + HLA32271 + Undefined + - + + + DQB1*05:288 + HLA32253 + Undefined + - + + + DQB1*05:289 + HLA32185 + Undefined + - + + + DQB1*05:290 + HLA32262 + Undefined + - + + + DQB1*05:291 + HLA32565 + Undefined + - + + + DQB1*05:292 + HLA32611 + Undefined + - + + + DQB1*05:293:01 + HLA32910 + Undefined + - + + + DQB1*05:293:02 + HLA34976 + Undefined + - + + + DQB1*05:294 + HLA33558 + Undefined + - + + + DQB1*05:295N + HLA34115 + NotExpressed + Null + + + DQB1*05:296 + HLA34420 + Undefined + - + + + DQB1*05:297 + HLA34417 + Undefined + - + + + DQB1*05:298 + HLA34603 + Undefined + - + + + DQB1*05:299 + HLA35210 + Undefined + - + + + DQB1*05:300 + HLA35009 + Undefined + - + + + DQB1*05:301 + HLA34974 + Undefined + - + + + DQB1*05:302 + HLA35048 + Undefined + - + + + DQB1*05:303 + HLA34878 + Undefined + - + + + DQB1*05:304 + HLA35689 + Undefined + - + + + DQB1*05:305 + HLA36201 + Undefined + - + + + DQB1*05:306 + HLA36247 + Undefined + - + + + DQB1*05:307 + HLA36205 + Undefined + - + + + DQB1*05:308 + HLA36113 + Undefined + - + + + DQB1*05:309 + HLA36086 + Undefined + - + + + DQB1*05:310 + HLA36287 + Undefined + - + + + DQB1*05:311 + HLA36471 + Undefined + - + + + DQB1*05:312 + HLA36472 + Undefined + - + + + DQB1*05:313Q + HLA36329 + Undefined + - + + + DQB1*05:314 + HLA36381 + Undefined + - + + + DQB1*05:315 + HLA36551 + Undefined + - + + + DQB1*05:316N + HLA36573 + NotExpressed + Null + + + DQB1*05:317 + HLA36326 + Undefined + - + + + DQB1*05:318 + HLA36379 + Undefined + - + + + DQB1*05:319 + HLA37067 + Undefined + - + + + DQB1*05:320 + HLA37070 + Undefined + - + + + DQB1*05:321 + HLA37133 + Undefined + - + + + DQB1*05:322 + HLA37437 + Undefined + - + + + DQB1*05:323 + HLA37581 + Undefined + - + + + DQB1*05:324 + HLA38077 + Undefined + - + + + DQB1*06:01:01:01 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DQ6(1) + + + DQB1*06:06 + HLA00651 + DQ5 + - + + + DQB1*06:07:01 + HLA00652 + DQ6 + - + + + DQB1*06:07:02 + HLA05768 + DQ6 + - + + + DQB1*06:08:01:01 + HLA00653 + DQ6 + DQ6(1) + + + DQB1*06:08:01:02 + HLA38141 + DQ6 + DQ6(1) + + + DQB1*06:08:02 + HLA02609 + DQ6 + DQ6(1) + + + DQB1*06:08:03 + HLA11886 + DQ6 + DQ6(1) + + + DQB1*06:09:01:01 + HLA00654 + DQ6 + DQ6(1) + + + DQB1*06:09:01:02 + HLA16360 + DQ6 + DQ6(1) + + + DQB1*06:09:01:03 + HLA36414 + DQ6 + DQ6(1) + + + DQB1*06:09:02 + HLA09275 + DQ6 + DQ6(1) + + + DQB1*06:09:03 + HLA09277 + DQ6 + DQ6(1) + + + DQB1*06:09:04 + HLA09937 + DQ6 + DQ6(1) + + + DQB1*06:09:05 + HLA11140 + DQ6 + DQ6(1) + + + DQB1*06:09:06 + HLA11677 + DQ6 + DQ6(1) + + + DQB1*06:09:07 + HLA17170 + DQ6 + DQ6(1) + + + DQB1*06:09:08 + HLA18639 + DQ6 + DQ6(1) + + + DQB1*06:09:09 + HLA18957 + DQ6 + DQ6(1) + + + DQB1*06:09:10 + HLA21141 + DQ6 + DQ6(1) + + + DQB1*06:09:11 + HLA24290 + DQ6 + DQ6(1) + + + DQB1*06:09:12 + HLA26098 + DQ6 + DQ6(1) + + + DQB1*06:10 + HLA00655 + DQ1 + - + + + DQB1*06:11:01:01 + HLA00656 + DQ1 + DQ1 + + + DQB1*06:11:01:02 + HLA29230 + DQ1 + DQ1 + + + DQB1*06:11:02 + HLA00657 + DQ1 + DQ1 + + + DQB1*06:11:03 + HLA11508 + DQ1 + DQ1 + + + DQB1*06:11:04 + HLA21857 + DQ1 + DQ1 + + + DQB1*06:12 + HLA00658 + DQ1 + DQ1 + + + DQB1*06:13:01 + HLA00659 + DQ6 + - + + + DQB1*06:13:02 + HLA09377 + DQ6 + - + + + DQB1*06:13:03 + HLA18815 + DQ6 + - + + + DQB1*06:14:01 + HLA00660 + DQ6 + DQ6(1) + + + DQB1*06:14:02 + HLA03431 + DQ6 + DQ6(1) + + + DQB1*06:14:03 + HLA14170 + DQ6 + DQ6(1) + + + DQB1*06:15:01 + HLA00661 + DQ6 + - + + + DQB1*06:15:02 + HLA09368 + DQ6 + - + + + DQB1*06:16 + HLA01006 + DQ6 + - + + + DQB1*06:17 + HLA01175 + DQ6 + - + + + DQB1*06:18:01 + HLA01446 + DQ6 + - + + + DQB1*06:18:02 + HLA11562 + DQ6 + - + + + DQB1*06:19:01 + HLA01460 + DQ6 + - + + + DQB1*06:19:02 + HLA11892 + DQ6 + - + + + DQB1*06:20 + HLA01612 + DQ6 + - + + + DQB1*06:21 + HLA01776 + DQ6 + - + + + DQB1*06:22:01 + HLA01967 + DQ6 + - + + + DQB1*06:22:02 + HLA09476 + DQ6 + - + + + DQB1*06:22:03 + HLA11600 + DQ6 + - + + + DQB1*06:23 + HLA02005 + DQ6 + - + + + DQB1*06:24 + HLA02182 + DQ6 + - + + + DQB1*06:25 + HLA02195 + DQ6 + DQ6(1) + + + DQB1*06:26N + HLA02221 + NotExpressed + Null + + + DQB1*06:27:01 + HLA02291 + DQ6 + - + + + DQB1*06:27:02 + HLA10281 + DQ6 + - + + + DQB1*06:28 + HLA02453 + DQ6 + - + + + DQB1*06:29 + HLA02696 + DQ6 + - + + + DQB1*06:30 + HLA02740 + DQ6 + - + + + DQB1*06:31 + HLA02917 + DQ6 + - + + + DQB1*06:32:01 + HLA02950 + DQ6 + - + + + DQB1*06:32:02 + HLA13810 + DQ6 + - + + + DQB1*06:33 + HLA02970 + DQ6 + - + + + DQB1*06:34 + HLA03114 + Undefined + - + + + DQB1*06:35 + HLA03809 + Undefined + - + + + DQB1*06:36 + HLA03979 + Undefined + - + + + DQB1*06:37 + HLA04119 + Undefined + - + + + DQB1*06:38 + HLA04357 + Undefined + - + + + DQB1*06:39 + HLA04358 + Undefined + - + + + DQB1*06:40 + HLA04737 + Undefined + - + + + DQB1*06:41:01:01 + HLA06179 + Undefined + - + + + DQB1*06:41:01:02 + HLA28775 + Undefined + - + + + DQB1*06:41:01:03 + HLA28781 + Undefined + - + + + DQB1*06:42 + HLA06180 + Undefined + - + + + DQB1*06:43 + HLA06272 + Undefined + - + + + DQB1*06:44 + HLA06518 + Undefined + - + + + DQB1*06:45 + HLA06876 + Undefined + - + + + DQB1*06:46 + HLA06877 + Undefined + - + + + DQB1*06:47 + HLA07414 + Undefined + - + + + DQB1*06:48:01 + HLA07539 + Undefined + - + + + DQB1*06:48:02 + HLA18695 + Undefined + - + + + DQB1*06:49 + HLA07820 + Undefined + - + + + DQB1*06:50 + HLA07922 + Undefined + - + + + DQB1*06:51:01 + HLA07934 + Undefined + - + + + DQB1*06:51:02 + HLA10256 + Undefined + - + + + DQB1*06:52 + HLA08082 + Undefined + - + + + DQB1*06:53:01 + HLA09222 + Undefined + - + + + DQB1*06:53:02 + HLA15318 + Undefined + - + + + DQB1*06:54N + HLA09223 + NotExpressed + Null + + + DQB1*06:55 + HLA09225 + Undefined + - + + + DQB1*06:56 + HLA09226 + Undefined + - + + + DQB1*06:57:01 + HLA09227 + Undefined + - + + + DQB1*06:57:02 + HLA28196 + Undefined + - + + + DQB1*06:58 + HLA09229 + Undefined + - + + + DQB1*06:59 + HLA09264 + Undefined + - + + + DQB1*06:60 + HLA09265 + Undefined + - + + + DQB1*06:61 + HLA09266 + Undefined + - + + + DQB1*06:62 + HLA09267 + Undefined + - + + + DQB1*06:63 + HLA09268 + Undefined + - + + + DQB1*06:64 + HLA09271 + Undefined + - + + + DQB1*06:65 + HLA09273 + Undefined + - + + + DQB1*06:66 + HLA09276 + Undefined + - + + + DQB1*06:67 + HLA09290 + Undefined + - + + + DQB1*06:68 + HLA09358 + Undefined + - + + + DQB1*06:69:01 + HLA09363 + Undefined + - + + + DQB1*06:69:02 + HLA17526 + Undefined + - + + + DQB1*06:70 + HLA09365 + Undefined + - + + + DQB1*06:71 + HLA09367 + Undefined + - + + + DQB1*06:72 + HLA09369 + Undefined + - + + + DQB1*06:73 + HLA09371 + Undefined + - + + + DQB1*06:74 + HLA09372 + Undefined + - + + + DQB1*06:75N + HLA09373 + NotExpressed + Null + + + DQB1*06:76 + HLA09374 + Undefined + - + + + DQB1*06:77N + HLA09375 + NotExpressed + Null + + + DQB1*06:78 + HLA09376 + Undefined + - + + + DQB1*06:79:01 + HLA09379 + Undefined + - + + + DQB1*06:79:02 + HLA11498 + Undefined + - + + + DQB1*06:80 + HLA09380 + Undefined + - + + + DQB1*06:81 + HLA09382 + Undefined + - + + + DQB1*06:82 + HLA09383 + Undefined + - + + + DQB1*06:83 + HLA09384 + Undefined + - + + + DQB1*06:84:01:01 + HLA09472 + Undefined + - + + + DQB1*06:84:01:02 + HLA28810 + Undefined + - + + + DQB1*06:85 + HLA09633 + Undefined + - + + + DQB1*06:86 + HLA09648 + Undefined + - + + + DQB1*06:87 + HLA09649 + Undefined + - + + + DQB1*06:88:01:01 + HLA09651 + Undefined + - + + + DQB1*06:88:01:02 + HLA28779 + Undefined + - + + + DQB1*06:89 + HLA09719 + Undefined + - + + + DQB1*06:90 + HLA09733 + Undefined + - + + + DQB1*06:91 + HLA09734 + Undefined + - + + + DQB1*06:92:02 + HLA22122 + Undefined + - + + + DQB1*06:92 + HLA09735 + Undefined + - + + + DQB1*06:93 + HLA09737 + Undefined + - + + + DQB1*06:94 + HLA09740 + Undefined + - + + + DQB1*06:95 + HLA09747 + Undefined + - + + + DQB1*06:96:01 + HLA09748 + Undefined + - + + + DQB1*06:96:02 + HLA18809 + Undefined + - + + + DQB1*06:97 + HLA09751 + Undefined + - + + + DQB1*06:98 + HLA09858 + Undefined + - + + + DQB1*06:99:01 + HLA09860 + Undefined + - + + + DQB1*06:99:02 + HLA11561 + Undefined + - + + + DQB1*06:99:03 + HLA23464 + Undefined + - + + + DQB1*06:100 + HLA09862 + Undefined + - + + + DQB1*06:101 + HLA09864 + Undefined + - + + + DQB1*06:102N + HLA09868 + NotExpressed + Null + + + DQB1*06:103 + HLA09870 + Undefined + - + + + DQB1*06:104 + HLA09872 + Undefined + - + + + DQB1*06:105 + HLA09873 + Undefined + - + + + DQB1*06:106 + HLA09926 + Undefined + - + + + DQB1*06:107 + HLA09927 + Undefined + - + + + DQB1*06:108 + HLA09929 + Undefined + - + + + DQB1*06:109 + HLA09930 + Undefined + - + + + DQB1*06:110 + HLA10113 + Undefined + - + + + DQB1*06:111 + HLA10167 + Undefined + - + + + DQB1*06:112N + HLA10242 + NotExpressed + Null + + + DQB1*06:113 + HLA10243 + Undefined + - + + + DQB1*06:114 + HLA10244 + Undefined + - + + + DQB1*06:115 + HLA10245 + Undefined + - + + + DQB1*06:116 + HLA10246 + Undefined + - + + + DQB1*06:117 + HLA10247 + Undefined + - + + + DQB1*06:118:01 + HLA10248 + Undefined + - + + + DQB1*06:118:02 + HLA12031 + Undefined + - + + + DQB1*06:118:03 + HLA16958 + Undefined + - + + + DQB1*06:118:04 + HLA32685 + Undefined + - + + + DQB1*06:119 + HLA10257 + Undefined + - + + + DQB1*06:120 + HLA10273 + Undefined + - + + + DQB1*06:121 + HLA10282 + Undefined + - + + + DQB1*06:122 + HLA10293 + Undefined + - + + + DQB1*06:123 + HLA10295 + Undefined + - + + + DQB1*06:124 + HLA10297 + Undefined + - + + + DQB1*06:125 + HLA10298 + Undefined + - + + + DQB1*06:126 + HLA10300 + Undefined + - + + + DQB1*06:127 + HLA10506 + Undefined + - + + + DQB1*06:128 + HLA10542 + Undefined + - + + + DQB1*06:129 + HLA10661 + Undefined + - + + + DQB1*06:130 + HLA11081 + Undefined + - + + + DQB1*06:131 + HLA11123 + Undefined + - + + + DQB1*06:132 + HLA11124 + Undefined + - + + + DQB1*06:133 + HLA11134 + Undefined + - + + + DQB1*06:134 + HLA11135 + Undefined + - + + + DQB1*06:135 + HLA11139 + Undefined + - + + + DQB1*06:136 + HLA11152 + Undefined + - + + + DQB1*06:137 + HLA11153 + Undefined + - + + + DQB1*06:138 + HLA11155 + Undefined + - + + + DQB1*06:139 + HLA11156 + Undefined + - + + + DQB1*06:140 + HLA11273 + Undefined + - + + + DQB1*06:141 + HLA11280 + Undefined + - + + + DQB1*06:142 + HLA11281 + Undefined + - + + + DQB1*06:143 + HLA11286 + Undefined + - + + + DQB1*06:144N + HLA11353 + NotExpressed + Null + + + DQB1*06:145:01 + HLA11354 + Undefined + - + + + DQB1*06:145:02 + HLA36118 + Undefined + - + + + DQB1*06:146:01 + HLA11367 + Undefined + - + + + DQB1*06:146:02 + HLA14173 + Undefined + - + + + DQB1*06:147 + HLA11368 + Undefined + - + + + DQB1*06:148 + HLA11489 + Undefined + - + + + DQB1*06:149 + HLA11588 + Undefined + - + + + DQB1*06:150 + HLA11599 + Undefined + - + + + DQB1*06:151 + HLA11685 + Undefined + - + + + DQB1*06:152 + HLA11686 + Undefined + - + + + DQB1*06:153:01 + HLA11879 + Undefined + - + + + DQB1*06:153:02 + HLA21326 + Undefined + - + + + DQB1*06:154 + HLA11880 + Undefined + - + + + DQB1*06:155 + HLA11885 + Undefined + - + + + DQB1*06:156 + HLA11894 + Undefined + - + + + DQB1*06:157 + HLA12025 + Undefined + - + + + DQB1*06:158N + HLA12030 + NotExpressed + Null + + + DQB1*06:159 + HLA12047 + Undefined + - + + + DQB1*06:160 + HLA12210 + Undefined + - + + + DQB1*06:161 + HLA12360 + Undefined + - + + + DQB1*06:162 + HLA12361 + Undefined + - + + + DQB1*06:163 + HLA12362 + Undefined + - + + + DQB1*06:164 + HLA12526 + Undefined + - + + + DQB1*06:165 + HLA12528 + Undefined + - + + + DQB1*06:166 + HLA12534 + Undefined + - + + + DQB1*06:167 + HLA12793 + Undefined + - + + + DQB1*06:168 + HLA13117 + Undefined + - + + + DQB1*06:169 + HLA13130 + Undefined + - + + + DQB1*06:170 + HLA13131 + Undefined + - + + + DQB1*06:171 + HLA13133 + Undefined + - + + + DQB1*06:172 + HLA13134 + Undefined + - + + + DQB1*06:173 + HLA13150 + Undefined + - + + + DQB1*06:174 + HLA13151 + Undefined + - + + + DQB1*06:175 + HLA13247 + Undefined + - + + + DQB1*06:176 + HLA13575 + Undefined + - + + + DQB1*06:177 + HLA13576 + Undefined + - + + + DQB1*06:178 + HLA13583 + Undefined + - + + + DQB1*06:179N + HLA13584 + NotExpressed + Null + + + DQB1*06:180 + HLA13501 + Undefined + - + + + DQB1*06:181 + HLA13677 + Undefined + - + + + DQB1*06:182 + HLA13684 + Undefined + - + + + DQB1*06:183 + HLA13813 + Undefined + - + + + DQB1*06:184 + HLA13882 + Undefined + - + + + DQB1*06:185 + HLA13916 + Undefined + - + + + DQB1*06:186 + HLA13924 + Undefined + - + + + DQB1*06:187 + HLA13927 + Undefined + - + + + DQB1*06:188 + HLA13932 + Undefined + - + + + DQB1*06:189 + HLA13934 + Undefined + - + + + DQB1*06:190:01 + HLA13771 + Undefined + - + + + DQB1*06:190:02 + HLA16564 + Undefined + - + + + DQB1*06:191 + HLA14038 + Undefined + - + + + DQB1*06:192 + HLA14043 + Undefined + - + + + DQB1*06:193N + HLA13981 + NotExpressed + Null + + + DQB1*06:194 + HLA14159 + Undefined + - + + + DQB1*06:195 + HLA14161 + Undefined + - + + + DQB1*06:196 + HLA14164 + Undefined + - + + + DQB1*06:197 + HLA14172 + Undefined + - + + + DQB1*06:198 + HLA14351 + Undefined + - + + + DQB1*06:199 + HLA14548 + Undefined + - + + + DQB1*06:200 + HLA14486 + Undefined + - + + + DQB1*06:201 + HLA14764 + Undefined + - + + + DQB1*06:202 + HLA14686 + Undefined + - + + + DQB1*06:203 + HLA15065 + Undefined + - + + + DQB1*06:204 + HLA15066 + Undefined + - + + + DQB1*06:205 + HLA14943 + Undefined + - + + + DQB1*06:206:01 + HLA15003 + Undefined + - + + + DQB1*06:206:02 + HLA16189 + Undefined + - + + + DQB1*06:207 + HLA15323 + Undefined + - + + + DQB1*06:208:01 + HLA15328 + Undefined + - + + + DQB1*06:208:02 + HLA36074 + Undefined + - + + + DQB1*06:209 + HLA15155 + Undefined + - + + + DQB1*06:210 + HLA15479 + Undefined + - + + + DQB1*06:211 + HLA15484 + Undefined + - + + + DQB1*06:212 + HLA15681 + Undefined + - + + + DQB1*06:213 + HLA15692 + Undefined + - + + + DQB1*06:214 + HLA15746 + Undefined + - + + + DQB1*06:215 + HLA15994 + Undefined + - + + + DQB1*06:216N + HLA16015 + NotExpressed + Null + + + DQB1*06:217 + HLA16016 + Undefined + - + + + DQB1*06:218 + HLA16133 + Undefined + - + + + DQB1*06:219 + HLA16134 + Undefined + - + + + DQB1*06:221 + HLA16149 + Undefined + - + + + DQB1*06:222 + HLA16153 + Undefined + - + + + DQB1*06:223 + HLA16164 + Undefined + - + + + DQB1*06:224 + HLA16165 + Undefined + - + + + DQB1*06:225 + HLA16166 + Undefined + - + + + DQB1*06:226 + HLA16183 + Undefined + - + + + DQB1*06:227 + HLA16184 + Undefined + - + + + DQB1*06:228 + HLA16191 + Undefined + - + + + DQB1*06:229 + HLA16560 + Undefined + - + + + DQB1*06:230 + HLA16624 + Undefined + - + + + DQB1*06:231 + HLA16776 + Undefined + - + + + DQB1*06:232 + HLA16781 + Undefined + - + + + DQB1*06:233 + HLA16838 + Undefined + - + + + DQB1*06:234 + HLA16956 + Undefined + - + + + DQB1*06:235 + HLA17025 + Undefined + - + + + DQB1*06:236 + HLA17026 + Undefined + - + + + DQB1*06:237 + HLA17291 + Undefined + - + + + DQB1*06:238 + HLA17328 + Undefined + - + + + DQB1*06:239 + HLA17428 + Undefined + - + + + DQB1*06:240 + HLA17429 + Undefined + - + + + DQB1*06:241 + HLA17522 + Undefined + - + + + DQB1*06:242 + HLA17642 + Undefined + - + + + DQB1*06:243 + HLA17693 + Undefined + - + + + DQB1*06:244 + HLA17905 + Undefined + - + + + DQB1*06:245 + HLA17907 + Undefined + - + + + DQB1*06:246 + HLA17908 + Undefined + - + + + DQB1*06:247 + HLA17909 + Undefined + - + + + DQB1*06:248 + HLA17914 + Undefined + - + + + DQB1*06:249 + HLA17918 + Undefined + - + + + DQB1*06:250 + HLA18239 + Undefined + - + + + DQB1*06:251 + HLA18186 + Undefined + - + + + DQB1*06:252N + HLA18187 + NotExpressed + Null + + + DQB1*06:253 + HLA18636 + Undefined + - + + + DQB1*06:254 + HLA18637 + Undefined + - + + + DQB1*06:255 + HLA18638 + Undefined + - + + + DQB1*06:256 + HLA18641 + Undefined + - + + + DQB1*06:257 + HLA18685 + Undefined + - + + + DQB1*06:258 + HLA18687 + Undefined + - + + + DQB1*06:259 + HLA18688 + Undefined + - + + + DQB1*06:260 + HLA18692 + Undefined + - + + + DQB1*06:261 + HLA18694 + Undefined + - + + + DQB1*06:262 + HLA18698 + Undefined + - + + + DQB1*06:263 + HLA18798 + Undefined + - + + + DQB1*06:264 + HLA18800 + Undefined + - + + + DQB1*06:265 + HLA18802 + Undefined + - + + + DQB1*06:266 + HLA18803 + Undefined + - + + + DQB1*06:267 + HLA18806 + Undefined + - + + + DQB1*06:268 + HLA18812 + Undefined + - + + + DQB1*06:269 + HLA18813 + Undefined + - + + + DQB1*06:270:01 + HLA18952 + Undefined + - + + + DQB1*06:270:02 + HLA22306 + Undefined + - + + + DQB1*06:271 + HLA18953 + Undefined + - + + + DQB1*06:272 + HLA18958 + Undefined + - + + + DQB1*06:273 + HLA18959 + Undefined + - + + + DQB1*06:274 + HLA18969 + Undefined + - + + + DQB1*06:275 + HLA19045 + Undefined + - + + + DQB1*06:276 + HLA19422 + Undefined + - + + + DQB1*06:277 + HLA19359 + Undefined + - + + + DQB1*06:278 + HLA19822 + Undefined + - + + + DQB1*06:279 + HLA19849 + Undefined + - + + + DQB1*06:280 + HLA19708 + Undefined + - + + + DQB1*06:281 + HLA19941 + Undefined + - + + + DQB1*06:282 + HLA19876 + Undefined + - + + + DQB1*06:283 + HLA19889 + Undefined + - + + + DQB1*06:284 + HLA19944 + Undefined + - + + + DQB1*06:285 + HLA19677 + Undefined + - + + + DQB1*06:286 + HLA19934 + Undefined + - + + + DQB1*06:287 + HLA20570 + Undefined + - + + + DQB1*06:288 + HLA20653 + Undefined + - + + + DQB1*06:289 + HLA20556 + Undefined + - + + + DQB1*06:290 + HLA20708 + Undefined + - + + + DQB1*06:291 + HLA20601 + Undefined + - + + + DQB1*06:292 + HLA21056 + Undefined + - + + + DQB1*06:293 + HLA20715 + Undefined + - + + + DQB1*06:294 + HLA20887 + Undefined + - + + + DQB1*06:295 + HLA20617 + Undefined + - + + + DQB1*06:296 + HLA20975 + Undefined + - + + + DQB1*06:297 + HLA21050 + Undefined + - + + + DQB1*06:298 + HLA20953 + Undefined + - + + + DQB1*06:299 + HLA20517 + Undefined + - + + + DQB1*06:300 + HLA21429 + Undefined + - + + + DQB1*06:301 + HLA21283 + Undefined + - + + + DQB1*06:302 + HLA21514 + Undefined + - + + + DQB1*06:303N + HLA22087 + NotExpressed + Null + + + DQB1*06:304N + HLA22133 + NotExpressed + Null + + + DQB1*06:305 + HLA22020 + Undefined + - + + + DQB1*06:306N + HLA22076 + NotExpressed + Null + + + DQB1*06:307 + HLA22126 + Undefined + - + + + DQB1*06:308N + HLA22139 + NotExpressed + Null + + + DQB1*06:309 + HLA22034 + Undefined + - + + + DQB1*06:310 + HLA22060 + Undefined + - + + + DQB1*06:311 + HLA21968 + Undefined + - + + + DQB1*06:312 + HLA22175 + Undefined + - + + + DQB1*06:313 + HLA22145 + Undefined + - + + + DQB1*06:314 + HLA22049 + Undefined + - + + + DQB1*06:315 + HLA22170 + Undefined + - + + + DQB1*06:316 + HLA22134 + Undefined + - + + + DQB1*06:317N + HLA22118 + NotExpressed + Null + + + DQB1*06:318 + HLA21971 + Undefined + - + + + DQB1*06:319:01 + HLA22201 + Undefined + - + + + DQB1*06:319:02 + HLA34403 + Undefined + - + + + DQB1*06:320 + HLA22594 + Undefined + - + + + DQB1*06:321 + HLA22244 + Undefined + - + + + DQB1*06:322:01 + HLA22217 + Undefined + - + + + DQB1*06:322:02 + HLA30609 + Undefined + - + + + DQB1*06:322:03 + HLA33149 + Undefined + - + + + DQB1*06:323 + HLA22493 + Undefined + - + + + DQB1*06:324 + HLA22529 + Undefined + - + + + DQB1*06:325 + HLA22721 + Undefined + - + + + DQB1*06:326 + HLA22785 + Undefined + - + + + DQB1*06:327 + HLA23427 + Undefined + - + + + DQB1*06:328 + HLA23743 + Undefined + - + + + DQB1*06:329 + HLA23562 + Undefined + - + + + DQB1*06:330N + HLA23263 + NotExpressed + Null + + + DQB1*06:331 + HLA23667 + Undefined + - + + + DQB1*06:332 + HLA23487 + Undefined + - + + + DQB1*06:333 + HLA23436 + Undefined + - + + + DQB1*06:334 + HLA23227 + Undefined + - + + + DQB1*06:335 + HLA23402 + Undefined + - + + + DQB1*06:336 + HLA23676 + Undefined + - + + + DQB1*06:337 + HLA23681 + Undefined + - + + + DQB1*06:338 + HLA23399 + Undefined + - + + + DQB1*06:339 + HLA23507 + Undefined + - + + + DQB1*06:340 + HLA23299 + Undefined + - + + + DQB1*06:341N + HLA23048 + NotExpressed + Null + + + DQB1*06:342 + HLA23772 + Undefined + - + + + DQB1*06:343 + HLA23211 + Undefined + - + + + DQB1*06:344 + HLA23067 + Undefined 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Undefined + - + + + DQB1*06:411 + HLA32250 + Undefined + - + + + DQB1*06:412 + HLA32270 + Undefined + - + + + DQB1*06:413 + HLA32175 + Undefined + - + + + DQB1*06:414N + HLA32580 + NotExpressed + Null + + + DQB1*06:415 + HLA32298 + Undefined + - + + + DQB1*06:416:01:01Q + HLA32534 + Undefined + - + + + DQB1*06:416:01:02Q + HLA37861 + Undefined + - + + + DQB1*06:417 + HLA33449 + Undefined + - + + + DQB1*06:418 + HLA33240 + Undefined + - + + + DQB1*06:419 + HLA33229 + Undefined + - + + + DQB1*06:420 + HLA33633 + Undefined + - + + + DQB1*06:421 + HLA33653 + Undefined + - + + + DQB1*06:422N + HLA33702 + NotExpressed + Null + + + DQB1*06:423N + HLA33784 + NotExpressed + Null + + + DQB1*06:424 + HLA33879 + Undefined + - + + + DQB1*06:425 + HLA34397 + Undefined + - + + + DQB1*06:426 + HLA34431 + Undefined + - + + + DQB1*06:427 + HLA34338 + Undefined + - + + + DQB1*06:428 + HLA34255 + Undefined + - + + + DQB1*06:429 + HLA34277 + Undefined + - + + + DQB1*06:430 + HLA34623 + Undefined + - + + + DQB1*06:431 + HLA34501 + Undefined + - + + + DQB1*06:432 + HLA34497 + Undefined + - + + + DQB1*06:433 + HLA34601 + Undefined + - + + + DQB1*06:434 + HLA35361 + Undefined + - + + + DQB1*06:435 + HLA35050 + Undefined + - + + + DQB1*06:436 + HLA35251 + Undefined + - + + + DQB1*06:437 + HLA34933 + Undefined + - + + + DQB1*06:438 + HLA35126 + Undefined + - + + + DQB1*06:439Q + HLA35318 + Undefined + - + + + DQB1*06:440 + HLA35218 + Undefined + - + + + DQB1*06:441 + HLA35285 + Undefined + - + + + DQB1*06:442 + HLA35598 + Undefined + - + + + DQB1*06:443 + HLA35469 + Undefined + - + + + DQB1*06:444 + HLA36185 + Undefined + - + + + DQB1*06:445 + HLA36005 + Undefined + - + + + DQB1*06:446 + HLA36258 + Undefined + - + + + DQB1*06:447N + HLA36128 + NotExpressed + Null + + + DQB1*06:448 + HLA36105 + Undefined + - + + + DQB1*06:449 + HLA36495 + Undefined + - + + + DQB1*06:450 + HLA36363 + Undefined + - + + + DQB1*06:451 + HLA36589 + Undefined + - + + + DQB1*06:452N + HLA36593 + NotExpressed + Null + 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Undefined + - + + + DQB1*06:475 + HLA37514 + Undefined + - + + + DQB1*06:476 + HLA38532 + Undefined + - + + + DQB1*06:477N + HLA38717 + NotExpressed + Null + + + DRB1*01:01:01:01 + HLA00664 + DR1 + DR1 + + + DRB1*01:01:01:02 + HLA25039 + DR1 + DR1 + + + DRB1*01:01:01:03 + HLA28708 + DR1 + DR1 + + + DRB1*01:01:01:04 + HLA28929 + DR1 + DR1 + + + DRB1*01:01:01:05 + HLA33782 + DR1 + DR1 + + + DRB1*01:01:01:06 + HLA35213 + DR1 + DR1 + + + DRB1*01:01:01:07 + HLA35310 + DR1 + DR1 + + + DRB1*01:01:01:08 + HLA35256 + DR1 + DR1 + + + DRB1*01:01:01:09 + HLA35182 + DR1 + DR1 + + + DRB1*01:01:01:10 + HLA35223 + DR1 + DR1 + + + DRB1*01:01:01:11 + HLA35141 + DR1 + DR1 + + + DRB1*01:01:01:12 + HLA35217 + DR1 + DR1 + + + DRB1*01:01:01:13 + HLA34969 + DR1 + DR1 + + + DRB1*01:01:01:14 + HLA35198 + DR1 + DR1 + + + DRB1*01:01:01:15 + HLA35913 + DR1 + DR1 + + + DRB1*01:01:01:16 + HLA35866 + DR1 + DR1 + + + DRB1*01:01:01:17 + HLA35947 + DR1 + DR1 + + + DRB1*01:01:01:18 + HLA36049 + DR1 + DR1 + + + DRB1*01:01:01:19 + HLA36057 + DR1 + DR1 + + + DRB1*01:01:02 + HLA01598 + DR1 + DR1 + + + DRB1*01:01:03 + HLA01869 + DR1 + DR1 + + + DRB1*01:01:04 + HLA03225 + DR1 + DR1 + + + DRB1*01:01:05 + HLA03373 + DR1 + DR1 + + + DRB1*01:01:06 + HLA03389 + DR1 + DR1 + + + DRB1*01:01:07 + HLA03390 + DR1 + DR1 + + + DRB1*01:01:08 + HLA03428 + DR1 + DR1 + + + DRB1*01:01:09 + HLA03448 + DR1 + DR1 + + + DRB1*01:01:10 + HLA03912 + DR1 + DR1 + + + DRB1*01:01:11 + HLA04370 + DR1 + DR1 + + + DRB1*01:01:12 + HLA04374 + DR1 + DR1 + + + DRB1*01:01:13 + HLA04375 + DR1 + DR1 + + + DRB1*01:01:14 + HLA04376 + DR1 + DR1 + + + DRB1*01:01:15 + HLA04385 + DR1 + DR1 + + + DRB1*01:01:16 + HLA04405 + DR1 + DR1 + + + DRB1*01:01:17 + HLA04613 + DR1 + DR1 + + + DRB1*01:01:18 + HLA04680 + DR1 + DR1 + + + DRB1*01:01:19 + HLA06502 + DR1 + DR1 + + + DRB1*01:01:20 + HLA06503 + DR1 + DR1 + + + DRB1*01:01:21 + HLA07538 + DR1 + DR1 + + + DRB1*01:01:22 + HLA07887 + DR1 + DR1 + + + DRB1*01:01:23 + HLA08771 + DR1 + DR1 + + + DRB1*01:01:24 + HLA09217 + DR1 + DR1 + + + DRB1*01:01:25 + HLA09218 + DR1 + DR1 + + + DRB1*01:01:26 + HLA09346 + DR1 + DR1 + + + DRB1*01:01:27 + HLA11690 + DR1 + DR1 + + + DRB1*01:01:28 + HLA11904 + DR1 + DR1 + + + DRB1*01:01:29 + HLA13291 + DR1 + DR1 + + + DRB1*01:01:30 + HLA16325 + DR1 + DR1 + + + DRB1*01:01:31 + HLA18788 + DR1 + DR1 + + + DRB1*01:01:32 + HLA19856 + DR1 + DR1 + + + DRB1*01:01:33 + HLA19616 + DR1 + DR1 + + + DRB1*01:01:34 + HLA26616 + DR1 + DR1 + + + DRB1*01:01:35 + HLA29018 + DR1 + DR1 + + + DRB1*01:01:36 + HLA29673 + DR1 + DR1 + + + DRB1*01:01:37 + HLA32991 + DR1 + DR1 + + + DRB1*01:01:38 + HLA34161 + DR1 + DR1 + + + DRB1*01:01:39 + HLA34163 + DR1 + DR1 + + + DRB1*01:01:40 + HLA34190 + DR1 + DR1 + + + DRB1*01:01:41 + HLA34669 + DR1 + DR1 + + + DRB1*01:01:42 + HLA35111 + DR1 + DR1 + + + DRB1*01:01:43 + HLA35136 + DR1 + DR1 + + + DRB1*01:01:44 + HLA35288 + DR1 + DR1 + + + DRB1*01:01:45 + HLA35273 + DR1 + DR1 + + + DRB1*01:01:46 + HLA35300 + DR1 + DR1 + + + DRB1*01:02:01:01 + HLA00665 + DR1 + DR1 + + + DRB1*01:02:01:02 + HLA21605 + DR1 + DR1 + + + DRB1*01:02:01:03 + HLA25067 + DR1 + DR1 + + + DRB1*01:02:01:04 + HLA36436 + DR1 + DR1 + + + DRB1*01:02:02 + HLA00666 + DR1 + DR1 + + + DRB1*01:02:03 + HLA01875 + DR1 + DR1 + + + DRB1*01:02:04 + HLA02001 + DR1 + DR1 + + + DRB1*01:02:05 + HLA03426 + DR1 + DR1 + + + DRB1*01:02:06 + HLA07152 + DR1 + DR1 + + + DRB1*01:02:07 + HLA07268 + DR1 + DR1 + + + DRB1*01:02:08 + HLA07276 + DR1 + DR1 + + + DRB1*01:02:09 + HLA10321 + DR1 + DR1 + + + DRB1*01:02:10 + HLA12439 + DR1 + DR1 + + + DRB1*01:02:11 + HLA13599 + DR1 + DR1 + + + DRB1*01:02:12 + HLA14188 + DR1 + DR1 + + + DRB1*01:02:13 + HLA17591 + DR1 + DR1 + + + DRB1*01:03:01:01 + HLA00667 + DR103/DR1 + DR103 + + + DRB1*01:03:01:02 + HLA35174 + DR103/DR1 + DR103 + + + DRB1*01:03:02 + HLA16793 + DR103/DR1 + DR103 + + + DRB1*01:03:03 + HLA19865 + DR103/DR1 + DR103 + + + DRB1*01:03:04 + HLA21890 + DR103/DR1 + DR103 + + + DRB1*01:03:05 + HLA28373 + DR103/DR1 + DR103 + + + DRB1*01:04:01 + HLA00668 + DR1 + DR1 + + + DRB1*01:04:02 + HLA38635 + DR1 + DR1 + + + DRB1*01:05 + HLA00669 + DR1 + - + + + DRB1*01:06 + HLA00670 + DR1 + - + + + DRB1*01:07 + HLA01307 + DR1 + DR1 + + + DRB1*01:08 + HLA01483 + DR1 + - + + + DRB1*01:09 + HLA01633 + DR1 + DR1 + + + DRB1*01:10 + HLA01671 + DR1 + - + + + DRB1*01:11:01 + HLA01811 + DR1 + - + + + DRB1*01:11:02 + HLA10322 + DR1 + - + + + DRB1*01:12 + HLA02056 + DR1 + - + + + DRB1*01:13 + HLA02173 + DR1 + DR1 + + + DRB1*01:14 + HLA02494 + DR1 + - + + + DRB1*01:15 + HLA02500 + DR1 + - + + + DRB1*01:16 + HLA02666 + DR1 + - + + + DRB1*01:17 + HLA03037 + Undefined + - + + + DRB1*01:18:01 + HLA03038 + Undefined + - + + + DRB1*01:18:02 + HLA16585 + Undefined + - + + + DRB1*01:19 + HLA03040 + Undefined + - + + + DRB1*01:20:01 + HLA03377 + Undefined + - + + + DRB1*01:20:02 + HLA13292 + Undefined + - + + + DRB1*01:21 + HLA03643 + Undefined + - + + + DRB1*01:22 + HLA03837 + Undefined + - + + + DRB1*01:23 + HLA04037 + Undefined + - + + + DRB1*01:24:01 + HLA04371 + Undefined + - + + + DRB1*01:24:02 + HLA08318 + Undefined + - + + + DRB1*01:25 + HLA04372 + Undefined + - + + + DRB1*01:26 + HLA04373 + Undefined + - + + + DRB1*01:27 + HLA04377 + Undefined + - + + + DRB1*01:28 + HLA04378 + Undefined + - + + + DRB1*01:29:01 + HLA04379 + Undefined + - + + + DRB1*01:29:02 + HLA09657 + Undefined + - + + + DRB1*01:30 + HLA04380 + Undefined + - + + + DRB1*01:31 + HLA04381 + Undefined + - + + + DRB1*01:32 + HLA04783 + Undefined + - + + + DRB1*01:33N + HLA05853 + NotExpressed + Null + + + DRB1*01:34 + HLA05864 + Undefined + - + + + DRB1*01:35 + HLA06514 + Undefined + - + + + DRB1*01:36 + HLA06523 + Undefined + - + + + DRB1*01:37 + HLA06839 + Undefined + - + + + DRB1*01:38 + HLA07174 + Undefined + - + + + DRB1*01:39N + HLA07265 + NotExpressed + Null + + + DRB1*01:40N + HLA07266 + NotExpressed + Null + + + DRB1*01:41 + HLA07267 + Undefined + - + + + DRB1*01:42 + HLA07269 + Undefined + - + + + DRB1*01:43 + HLA07270 + Undefined + - + + + DRB1*01:44:01 + HLA07271 + Undefined + - + + + DRB1*01:44:02 + HLA12060 + Undefined + - + + + DRB1*01:45 + HLA07327 + Undefined + - + + + DRB1*01:46 + HLA08313 + Undefined + - + + + DRB1*01:47 + HLA07886 + Undefined + - + + + DRB1*01:48 + HLA07888 + Undefined + - + + + DRB1*01:49 + HLA07889 + Undefined + - + + + DRB1*01:50 + HLA08604 + Undefined + - + + + DRB1*01:51 + HLA08772 + Undefined + - + + + DRB1*01:52N + HLA08773 + NotExpressed + Null + + + DRB1*01:53 + HLA08774 + Undefined + - + + + DRB1*01:54 + HLA08886 + Undefined + - + + + DRB1*01:55 + HLA09073 + Undefined + - + + + DRB1*01:56 + HLA09110 + Undefined + - + + + DRB1*01:57 + HLA09168 + Undefined + - + + + DRB1*01:58 + HLA09219 + Undefined + - + + + DRB1*01:59 + HLA09766 + Undefined + - + + + DRB1*01:60 + HLA10164 + Undefined + - + + + DRB1*01:61 + HLA11179 + Undefined + - + + + DRB1*01:62:01N + HLA11291 + NotExpressed + Null + + + DRB1*01:62:02N + HLA26024 + NotExpressed + Null + + + DRB1*01:63 + HLA11905 + Undefined + - + + + DRB1*01:64 + HLA12221 + Undefined + - + + + DRB1*01:65:01 + HLA12536 + Undefined + - + + + DRB1*01:65:02 + HLA14356 + Undefined + - + + + DRB1*01:66 + HLA12610 + Undefined + - + + + DRB1*01:67 + HLA12674 + Undefined + - + + + DRB1*01:68N + HLA13293 + NotExpressed + Null + + + DRB1*01:69 + HLA13294 + Undefined + - + + + DRB1*01:70 + HLA13295 + Undefined + - + + + DRB1*01:71 + HLA13598 + Undefined + - + + + DRB1*01:72 + HLA14189 + Undefined + - + + + DRB1*01:73 + HLA14772 + Undefined + - + + + DRB1*01:74 + HLA14687 + Undefined + - + + + DRB1*01:75 + HLA15085 + Undefined + - + + + DRB1*01:76 + HLA15709 + Undefined + - + + + DRB1*01:77 + HLA15625 + Undefined + - + + + DRB1*01:78 + HLA16002 + Undefined + - + + + DRB1*01:79 + HLA16966 + Undefined + - + + + DRB1*01:80 + HLA16967 + Undefined + - + + + DRB1*01:81 + HLA17042 + Undefined + - + + + DRB1*01:82 + HLA17346 + Undefined + - + + + DRB1*01:83 + HLA17349 + Undefined + - + + + DRB1*01:84 + HLA17660 + Undefined + - + + + 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Undefined + - + + + DRB4*01:77 + HLA20749 + Undefined + - + + + DRB4*01:78 + HLA20625 + Undefined + - + + + DRB4*01:79 + HLA20586 + Undefined + - + + + DRB4*01:80N + HLA21562 + NotExpressed + Null + + + DRB4*01:81 + HLA21227 + Undefined + - + + + DRB4*01:82 + HLA21568 + Undefined + - + + + DRB4*01:83 + HLA21459 + Undefined + - + + + DRB4*01:84N + HLA21216 + NotExpressed + Null + + + DRB4*01:85 + HLA21905 + Undefined + - + + + DRB4*01:86 + HLA21774 + Undefined + - + + + DRB4*01:87 + HLA22622 + Undefined + - + + + DRB4*01:88 + HLA22631 + Undefined + - + + + DRB4*01:89 + HLA22349 + Undefined + - + + + DRB4*01:90 + HLA22202 + Undefined + - + + + DRB4*01:91 + HLA22588 + Undefined + - + + + DRB4*01:92 + HLA22397 + Undefined + - + + + DRB4*01:93 + HLA22252 + Undefined + - + + + DRB4*01:94 + HLA23596 + Undefined + - + + + DRB4*01:95 + HLA23137 + Undefined + - + + + DRB4*01:96 + HLA23132 + Undefined + - + + + DRB4*01:97 + HLA23501 + Undefined + - + + + DRB4*01:98 + HLA23615 + Undefined + - + + + DRB4*01:99 + HLA23389 + Undefined + - + + + DRB4*01:100 + HLA23628 + Undefined + - + + + DRB4*01:101 + HLA23381 + Undefined + - + + + DRB4*01:102 + HLA23321 + Undefined + - + + + DRB4*01:103 + HLA23313 + Undefined + - + + + DRB4*01:104 + HLA23054 + Undefined + - + + + DRB4*01:105 + HLA23639 + Undefined + - + + + DRB4*01:106 + HLA23452 + Undefined + - + + + DRB4*01:107 + HLA23438 + Undefined + - + + + DRB4*01:108N + HLA24284 + NotExpressed + Null + + + DRB4*01:109 + HLA24228 + Undefined + - + + + DRB4*01:110 + HLA23912 + Undefined + - + + + DRB4*01:111 + HLA24130 + Undefined + - + + + DRB4*01:112 + HLA24266 + Undefined + - + + + DRB4*01:113N + HLA24119 + NotExpressed + Null + + + DRB4*01:114 + HLA23830 + Undefined + - + + + DRB4*01:115N + HLA24025 + NotExpressed + Null + + + DRB4*01:116 + HLA23858 + Undefined + - + + + DRB4*01:117 + HLA24749 + Undefined + - + + + DRB4*01:118 + HLA24874 + Undefined + - + + + DRB4*01:119 + HLA25855 + Undefined + - + + + DRB4*01:120 + HLA25994 + Undefined + - + + + DRB4*01:121N + HLA25805 + NotExpressed + Null + + + DRB4*01:122 + HLA26299 + Undefined + - + + + DRB4*01:123 + HLA26580 + Undefined + - + + + DRB4*01:124 + HLA26722 + Undefined + - + + + DRB4*01:125 + HLA26946 + Undefined + - + + + DRB4*01:126 + HLA28536 + Undefined + - + + + DRB4*01:127 + HLA28537 + Undefined + - + + + DRB4*01:128N + HLA28538 + NotExpressed + Null + + + DRB4*01:129 + HLA28539 + Undefined + - + + + DRB4*01:130 + HLA28540 + Undefined + - + + + DRB4*01:131 + HLA28541 + Undefined + - + + + DRB4*01:132 + HLA28542 + Undefined + - + + + DRB4*01:133 + HLA28545 + Undefined + - + + + DRB4*01:134 + HLA28680 + Undefined + - + + + DRB4*01:135 + HLA28874 + Undefined + - + + + DRB4*01:136 + HLA28875 + Undefined + - + + + DRB4*01:137 + HLA28876 + Undefined + - + + + DRB4*01:138 + HLA29155 + Undefined + - + + + DRB4*01:139 + HLA29839 + Undefined + - + + + DRB4*01:140 + HLA30269 + Undefined + - + + + DRB4*01:141 + HLA30386 + Undefined + - + + + DRB4*01:142 + HLA30343 + Undefined + - + + + DRB4*01:143 + HLA30378 + Undefined + - + + + DRB4*01:144 + HLA30430 + Undefined + - + + + DRB4*01:145N + HLA30677 + NotExpressed + Null + + + DRB4*01:146 + HLA30601 + Undefined + - + + + DRB4*01:147 + HLA31372 + Undefined + - + + + DRB4*01:148 + HLA31395 + Undefined + - + + + DRB4*01:149N + HLA31451 + NotExpressed + Null + + + DRB4*01:150 + HLA31977 + Undefined + - + + + DRB4*01:151 + HLA32287 + Undefined + - + + + DRB4*01:152 + HLA32168 + Undefined + - + + + DRB4*01:153 + HLA32726 + Undefined + - + + + DRB4*01:154 + HLA32911 + Undefined + - + + + DRB4*01:155 + HLA34347 + Undefined + - + + + DRB4*01:156 + HLA34373 + Undefined + - + + + DRB4*01:157 + HLA34262 + Undefined + - + + + DRB4*01:158 + HLA35307 + Undefined + - + + + DRB4*01:159N + HLA34925 + NotExpressed + Null + + + DRB4*01:160 + HLA34958 + Undefined + - + + + DRB4*01:161 + HLA34898 + Undefined + - + + + DRB4*01:162N + HLA35013 + NotExpressed + Null + + + DRB4*01:163 + HLA35953 + Undefined + - + + + DRB4*01:164 + HLA36154 + Undefined + - + + + DRB4*01:165N + HLA36512 + NotExpressed + Null + + + DRB4*01:166 + HLA36453 + Undefined + - + + + DRB4*01:167 + HLA36603 + Undefined + - + + + DRB4*01:168 + HLA36964 + Undefined + - + + + DRB4*01:169 + HLA37076 + Undefined + - + + + DRB4*01:170 + HLA37332 + Undefined + - + + + DRB4*01:171 + HLA37293 + Undefined + - + + + DRB4*01:172 + HLA37189 + Undefined + - + + + DRB4*01:173 + HLA38034 + Undefined + - + + + DRB4*01:174 + HLA38073 + Undefined + - + + + DRB4*01:175 + HLA38471 + Undefined + - + + + DRB4*01:176 + HLA38466 + Undefined + - + + + DRB4*01:177 + HLA38352 + Undefined + - + + + DRB4*01:178 + HLA38705 + Undefined + - + + + DRB4*02:01N + HLA00913 + NotExpressed + Null + + + DRB4*03:01N + HLA00914 + NotExpressed + Null + + + DRB5*01:01:01:01 + HLA00915 + DR51 + DR51 + + + DRB5*01:01:01:02 + HLA19221 + DR51 + DR51 + + + DRB5*01:01:01:03 + HLA22931 + DR51 + DR51 + + + DRB5*01:01:01:04 + HLA26632 + DR51 + DR51 + + + DRB5*01:01:01:05 + HLA29244 + DR51 + DR51 + + + DRB5*01:01:01:06 + HLA29245 + DR51 + DR51 + + + DRB5*01:01:02 + HLA00916 + DR51 + DR51 + + + DRB5*01:01:03 + HLA14577 + DR51 + DR51 + + + DRB5*01:01:04 + HLA22652 + DR51 + DR51 + + + DRB5*01:01:05 + HLA24150 + DR51 + DR51 + + + DRB5*01:01:06 + HLA27511 + DR51 + DR51 + + + DRB5*01:01:07 + HLA28553 + DR51 + DR51 + + + DRB5*01:01:08 + HLA31398 + DR51 + DR51 + + + DRB5*01:01:09 + HLA31342 + DR51 + DR51 + + + DRB5*01:01:10 + HLA33374 + DR51 + DR51 + + + DRB5*01:01:11 + HLA34056 + DR51 + DR51 + + + DRB5*01:01:12 + HLA35042 + DR51 + DR51 + + + DRB5*01:01:13 + HLA38126 + DR51 + DR51 + + + DRB5*01:02:01 + HLA00917 + DR51 + DR51 + + + DRB5*01:02:02 + HLA28547 + DR51 + DR51 + + + DRB5*01:02:03 + HLA37617 + DR51 + DR51 + + + DRB5*01:02:04 + HLA38092 + DR51 + DR51 + + + DRB5*01:03 + HLA00918 + Undefined + - + + + DRB5*01:04 + HLA00919 + Undefined + - + + + DRB5*01:05 + HLA00920 + Undefined + - + + + DRB5*01:06 + HLA00921 + Undefined + - + + + DRB5*01:07 + HLA00922 + DR51 + DR51 + + + DRB5*01:08:01N + HLA00923 + NotExpressed + Null + + + DRB5*01:08:02N + HLA23529 + NotExpressed + Null + + + DRB5*01:09 + HLA00924 + Undefined + - + + + DRB5*01:10N + HLA01012 + NotExpressed + Null + + + DRB5*01:11 + HLA01638 + Undefined + - + + + DRB5*01:12 + HLA01634 + Undefined + - + + + DRB5*01:13 + HLA01871 + Undefined + - + + + DRB5*01:14 + HLA04132 + Undefined + - + + + DRB5*01:15 + HLA11771 + Undefined + - + + + DRB5*01:16 + HLA14113 + Undefined + - + + + DRB5*01:17 + HLA14576 + Undefined + - + + + DRB5*01:18 + HLA14666 + Undefined + - + + + DRB5*01:19 + HLA15020 + Undefined + - + + + DRB5*01:20 + HLA15021 + Undefined + - + + + DRB5*01:21 + HLA15023 + Undefined + - + + + DRB5*01:22:01 + HLA15024 + Undefined + - + + + DRB5*01:22:02 + HLA22552 + Undefined + - + + + DRB5*01:23 + HLA15434 + Undefined + - + + + DRB5*01:24 + HLA15435 + Undefined + - + + + DRB5*01:25 + HLA15436 + Undefined + - + + + DRB5*01:26 + HLA15437 + Undefined + - + + + DRB5*01:27N + HLA16639 + NotExpressed + Null + + + DRB5*01:28 + HLA16592 + Undefined + - + + + DRB5*01:29 + HLA16593 + Undefined + - + + + DRB5*01:30 + HLA16970 + Undefined + - + + + DRB5*01:31 + HLA17083 + Undefined + - + + + DRB5*01:32 + HLA17542 + Undefined + - + + + DRB5*01:33 + HLA17543 + Undefined + - + + + DRB5*01:34 + HLA17544 + Undefined + - + + + DRB5*01:35 + HLA17545 + Undefined + - + + + DRB5*01:36 + HLA18633 + Undefined + - + + + DRB5*01:37 + HLA18795 + Undefined + - + + + DRB5*01:38 + HLA18796 + Undefined + - + + + DRB5*01:39 + HLA18797 + Undefined + - + + + DRB5*01:40 + HLA19456 + Undefined + - + + + DRB5*01:41 + HLA19854 + Undefined + - + + + DRB5*01:42 + HLA19887 + Undefined + - + + + DRB5*01:43 + HLA20797 + Undefined + - + + + DRB5*01:44 + HLA20781 + Undefined + - + + + DRB5*01:45 + HLA20919 + Undefined + - + + + DRB5*01:46 + HLA20988 + Undefined + - + + + DRB5*01:47 + HLA21083 + Undefined + - + + + DRB5*01:48N + HLA20956 + NotExpressed + Null + + + DRB5*01:49N + HLA21511 + NotExpressed + Null + + + DRB5*01:50 + HLA21368 + Undefined + - + + + DRB5*01:51 + HLA21269 + Undefined + - + + + DRB5*01:52N + HLA22419 + NotExpressed + Null + + + DRB5*01:53N + HLA22441 + NotExpressed + Null + + + DRB5*01:54 + HLA22352 + Undefined + - + + + DRB5*01:55 + HLA22566 + Undefined + - + + + DRB5*01:56 + HLA23205 + Undefined + - + + + DRB5*01:57 + HLA23525 + Undefined + - + + + DRB5*01:58N + HLA23034 + NotExpressed + Null + + + DRB5*01:59 + HLA23253 + Undefined + - + + + DRB5*01:60 + HLA23795 + Undefined + - + + + DRB5*01:61 + HLA23819 + Undefined + - + + + DRB5*01:62 + HLA23694 + Undefined + - + + + DRB5*01:63:01 + HLA23499 + Undefined + - + + + DRB5*01:63:02 + HLA23014 + Undefined + - + + + DRB5*01:64 + HLA23203 + Undefined + - + + + DRB5*01:65 + HLA23379 + Undefined + - + + + DRB5*01:66 + HLA23486 + Undefined + - + + + DRB5*01:67N + HLA23413 + NotExpressed + Null + + + DRB5*01:68N + HLA23098 + NotExpressed + Null + + + DRB5*01:69 + HLA23336 + Undefined + - + + + DRB5*01:70 + HLA23771 + Undefined + - + + + DRB5*01:71N + HLA24333 + NotExpressed + Null + + + DRB5*01:72 + HLA24035 + Undefined + - + + + DRB5*01:73 + HLA24242 + Undefined + - + + + DRB5*01:74 + HLA24073 + Undefined + - + + + DRB5*01:75 + HLA24305 + Undefined + - + + + DRB5*01:76 + HLA24091 + Undefined + - + + + DRB5*01:77 + HLA24090 + Undefined + - + + + DRB5*01:78 + HLA24152 + Undefined + - + + + DRB5*01:79Q + HLA24143 + Undefined + - + + + DRB5*01:80 + HLA24196 + Undefined + - + + + DRB5*01:81N + HLA24326 + NotExpressed + Null + + + DRB5*01:82 + HLA23934 + Undefined + - + + + DRB5*01:83N + HLA26082 + NotExpressed + Null + + + DRB5*01:84 + HLA27211 + Undefined + - + + + DRB5*01:85 + HLA26967 + Undefined + - + + + DRB5*01:86 + HLA27508 + Undefined + - + + + DRB5*01:87 + HLA27509 + Undefined + - + + + DRB5*01:88 + HLA27510 + Undefined + - + + + DRB5*01:89 + HLA27792 + Undefined + - + + + DRB5*01:90 + HLA28250 + Undefined + - + + + DRB5*01:91 + HLA28465 + Undefined + - + + + DRB5*01:92N + HLA28552 + NotExpressed + Null + + + DRB5*01:93 + HLA28546 + Undefined + - + + + DRB5*01:94 + HLA28548 + Undefined + - + + + DRB5*01:95 + HLA28549 + Undefined + - + + + DRB5*01:96 + HLA28550 + Undefined + - + + + DRB5*01:97 + HLA28551 + Undefined + - + + + DRB5*01:98 + HLA28877 + Undefined + - + + + DRB5*01:99 + HLA29024 + Undefined + - + + + DRB5*01:100 + HLA29202 + Undefined + - + + + DRB5*01:101N + HLA29298 + NotExpressed + Null + + + DRB5*01:102 + HLA29291 + Undefined + - + + + DRB5*01:103 + HLA29831 + Undefined + - + + + DRB5*01:104 + HLA29852 + Undefined + - + + + DRB5*01:105 + HLA29848 + Undefined + - + + + DRB5*01:106 + HLA29834 + Undefined + - + + + DRB5*01:107 + HLA29850 + Undefined + - + + + DRB5*01:108 + HLA30275 + Undefined + - + + + DRB5*01:109 + HLA30273 + Undefined + - + + + DRB5*01:110 + HLA30894 + Undefined + - + + + DRB5*01:111 + HLA31000 + Undefined + - + + + DRB5*01:112 + HLA30927 + Undefined + - + + + DRB5*01:113 + HLA31483 + Undefined + - + + + DRB5*01:114 + HLA31496 + Undefined + - + + + DRB5*01:115 + HLA33102 + Undefined + - + + + DRB5*01:116 + HLA33451 + Undefined + - + + + DRB5*01:117 + HLA33389 + Undefined + - + + + DRB5*01:118 + HLA34169 + Undefined + - + + + DRB5*01:119 + HLA34308 + Undefined + - + + + DRB5*01:120N + HLA34870 + NotExpressed + Null + + + DRB5*01:121N + HLA34937 + NotExpressed + Null + + + DRB5*01:122 + HLA35145 + Undefined + - + + + DRB5*01:123 + HLA35345 + Undefined + - + + + DRB5*01:124 + HLA34884 + Undefined + - + + + DRB5*01:125N + HLA35312 + NotExpressed + Null + + + DRB5*01:126 + HLA34908 + Undefined + - + + + DRB5*01:127N + HLA35477 + NotExpressed + Null + + + DRB5*01:128 + HLA35695 + Undefined + - + + + DRB5*01:129 + HLA35793 + Undefined + - + + + DRB5*01:130 + HLA36684 + Undefined + - + + + DRB5*01:131N + HLA37109 + NotExpressed + Null + + + DRB5*01:132 + HLA37085 + Undefined + - + + + DRB5*01:133 + HLA37400 + Undefined + - + + + DRB5*01:134N + HLA37574 + NotExpressed + Null + + + DRB5*01:135 + HLA38003 + Undefined + - + + + DRB5*02:02:01 + HLA00926 + DR51 + DR51 + + + DRB5*02:02:02 + HLA17154 + DR51 + DR51 + + + DRB5*02:02:03 + HLA19314 + DR51 + DR51 + + + DRB5*02:02:04 + HLA31311 + DR51 + DR51 + + + DRB5*02:03 + HLA00927 + Undefined + - + + + DRB5*02:04 + HLA00928 + Undefined + - + + + DRB5*02:05 + HLA01280 + Undefined + - + + + DRB5*02:06 + HLA08085 + Undefined + - + + + DRB5*02:07 + HLA14667 + Undefined + - + + + DRB5*02:08 + HLA15022 + Undefined + - + + + DRB5*02:09 + HLA15025 + Undefined + - + + + DRB5*02:10 + HLA15438 + Undefined + - + + + DRB5*02:11 + HLA15439 + Undefined + - + + + DRB5*02:12 + HLA15440 + Undefined + - + + + DRB5*02:13 + HLA15441 + Undefined + - + + + DRB5*02:14 + HLA15442 + Undefined + - + + + DRB5*02:15 + HLA15716 + Undefined + - + + + DRB5*02:16 + HLA16003 + Undefined + - + + + DRB5*02:17 + HLA17546 + Undefined + - + + + DRB5*02:18 + HLA18070 + Undefined + - + + + DRB5*02:19N + HLA18634 + NotExpressed + Null + + + DRB5*02:20 + HLA18821 + Undefined + - + + + DRB5*02:21:01 + HLA19672 + Undefined + - + + + DRB5*02:21:02 + HLA37363 + Undefined + - + + + DRB5*02:22 + HLA19597 + Undefined + - + + + DRB5*02:23 + HLA20572 + Undefined + - + + + DRB5*02:24 + HLA21461 + Undefined + - + + + DRB5*02:25N + HLA23635 + NotExpressed + Null + + + DRB5*02:26N + HLA23474 + NotExpressed + Null + + + DRB5*02:27 + HLA23493 + Undefined + - + + + DRB5*02:28 + HLA23274 + Undefined + - + + + DRB5*02:29 + HLA24319 + Undefined + - + + + DRB5*02:30 + HLA30670 + Undefined + - + + + DRB5*02:31 + HLA34035 + Undefined + - + + + DRB5*02:32 + HLA35002 + Undefined + - + + + DRB5*02:33 + HLA35148 + Undefined + - + + + DRB5*02:34 + HLA35698 + Undefined + - + + + DRB5*02:35 + HLA36159 + Undefined + - + + + DRB5*02:36 + HLA36090 + Undefined + - + + + DRB5*02:37 + HLA36498 + Undefined + - + + + DRB5*02:38 + HLA38065 + Undefined + - + + From af9fd4693ce5b0e52d15c557901163553f5ff35b Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Wed, 8 May 2024 11:27:14 -0500 Subject: [PATCH 02/23] Read CareDX XML file, use rel_dna_ser in Score6 serology lookups --- .../unet/parser/util/SerotypeEquivalence.java | 52 ++++++++++++++++--- .../unet/parser/util/XmlScore6Parser.java | 7 +-- 2 files changed, 49 insertions(+), 10 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index a648710f..0c16c897 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -23,6 +23,7 @@ import java.io.IOException; import java.io.InputStream; +import java.util.Set; import org.jsoup.Jsoup; import org.jsoup.nodes.Document; import org.jsoup.nodes.Element; @@ -32,27 +33,33 @@ import org.pankratzlab.unet.deprecated.hla.SeroType; import com.google.common.collect.ImmutableMap; import com.google.common.collect.ImmutableMap.Builder; +import com.google.common.collect.Sets; /** Utility class recording the mapping of genotypes to reported serotypes */ public final class SerotypeEquivalence { private static final String CAREDX_FILE = "ExpertWhoSerology_20240110_3.54.xml"; - private static final ImmutableMap equivalencies; + private static final ImmutableMap careDxEquivalencies; + private static final ImmutableMap manualEquivalencies; + + private static final Set INVALID = + Sets.newHashSet(null, "-", "Undefined", "Null", "NotExpressed", "Blank"); static { - equivalencies = buildOldLookup(); + careDxEquivalencies = buildLookupFromCareDxXMLFile(); + manualEquivalencies = buildManualOverrideLookup(); } - private static ImmutableMap buildNewLookup() { + private static ImmutableMap buildLookupFromCareDxXMLFile() { Builder builder = ImmutableMap.builder(); try (InputStream xmlStream = SerotypeEquivalence.class.getClassLoader().getResourceAsStream(CAREDX_FILE)) { Document parsed = Jsoup.parse(xmlStream, "UTF-8", "http://example.com"); - Elements elementsByTag = element.getElementsByTag(SINGLE_LOCUS_TAG); + Elements elementsByTag = parsed.getElementsByTag("allele"); for (Element e : elementsByTag) { - processLocus(builder, e); + processAllele(builder, e); } } catch (IOException e) { @@ -63,7 +70,38 @@ private static ImmutableMap buildNewLookup() { return builder.build(); } - private static ImmutableMap buildOldLookup() { + private static void processAllele(Builder builder, Element e) { + Element elementById = e.getElementsByTag("allelename").get(0); + if (elementById == null) { + elementById = e.getElementsByTag("alleleName").get(0); + } + if (elementById == null) { + System.err.println("Couldn't find allele name: " + e.toString()); + return; + } + final String alleleText = elementById.text(); + HLAType allele = HLAType.valueOf(alleleText); + Elements expertElements = e.getElementsByTag("expert"); + String careDxSeroText = expertElements.isEmpty() ? null : expertElements.get(0).text(); + Elements whoElements = e.getElementsByTag("WHO"); + String whoSeroText = whoElements.isEmpty() ? null : whoElements.get(0).text(); + if (INVALID.contains(careDxSeroText) && INVALID.contains(whoSeroText)) + return; + + try { + HLALocus locus = HLALocus.valueOf("" + careDxSeroText.charAt(0)); + put(builder, careDxSeroText.substring(1), locus, allele.specString()); + } catch (IllegalArgumentException e1) { + try { + HLALocus locus = HLALocus.valueOf("" + whoSeroText.charAt(0)); + put(builder, whoSeroText.substring(1), locus, allele.specString()); + } catch (IllegalArgumentException e2) { + return; + } + } + } + + private static ImmutableMap buildManualOverrideLookup() { // Build the equivalencies map Builder builder = ImmutableMap.builder(); // TODO would be nice to read this from a file instead @@ -126,6 +164,6 @@ public static SeroType get(HLAType allele) { // All the equivalencies are based on 2-field alleles allele = new HLAType(allele.locus(), allele.spec().subList(0, 2)); } - return equivalencies.get(allele); + return manualEquivalencies.getOrDefault(allele, careDxEquivalencies.get(allele)); } } diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java index b2e98ee3..ab031478 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java @@ -941,15 +941,16 @@ private static String getAlleleLookup(ResultCombination combination) { SeroType st2 = combination.getAntigenCombination(); if (st.compareTo(st1) != 0 || st.compareTo(st2) != 0 || st1.compareTo(st2) != 0) { - System.out.println( - "Discrepant lookup (special | equivSafe | parsed): " + st + " | " + st1 + " | " + st2); + System.err.println( + "Discrepant lookup (score6 | equivSafe | file):\t" + st + "\t" + st1 + "\t" + st2); } return st.specString(); } + // TODO why not return combination.antigenCombination? // Not a special case allele - use standard rules - return getAlleleSpec(combination); + return combination.alleleCombination.equivSafe().specString(); } /** @return The {@link HLAType} specificity of an allele + antigen pairing */ From 1641936600e27b69288690122b8fe12a1ecd7b9e Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Tue, 7 May 2024 12:41:17 -0500 Subject: [PATCH 03/23] Updates to DonorCheck Fix thread bugs in FileInputController Use new BackgroundDataProcessor to allow loading spinner to show Change class name to StyleableContingentChoiceDialog Add CIWD-only checkbox to StyleableContingentChoiceDialog Fix bugs in StyleableContingentChoiceDialog: - disable ok button until proper selection is made - disable second combo box until proper first selection is made --- pom.xml | 5 + ...a => StyleableContingentChoiceDialog.java} | 102 ++++- .../unet/jfx/wizard/FileInputController.java | 92 +++-- .../unet/model/ValidationModelBuilder.java | 373 ++++++++++++------ .../unet/parser/util/XmlScore6Parser.java | 40 +- 5 files changed, 425 insertions(+), 187 deletions(-) rename src/main/java/org/pankratzlab/unet/jfx/{StyleableChoiceDialog.java => StyleableContingentChoiceDialog.java} (69%) diff --git a/pom.xml b/pom.xml index c988612c..51214572 100644 --- a/pom.xml +++ b/pom.xml @@ -73,6 +73,11 @@ + + org.pankratzlab + BackgroundDataProcessor-java8 + 1.0-SNAPSHOT + org.apache.maven maven-model diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java similarity index 69% rename from src/main/java/org/pankratzlab/unet/jfx/StyleableChoiceDialog.java rename to src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index c3228e92..b69b0cdc 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -1,16 +1,21 @@ package org.pankratzlab.unet.jfx; +import java.util.ArrayList; import java.util.Collection; import java.util.Map; +import java.util.function.Predicate; +import java.util.stream.Collectors; import com.google.common.collect.Multimap; import com.sun.javafx.scene.control.skin.resources.ControlResources; import javafx.application.Platform; +import javafx.beans.binding.Bindings; import javafx.beans.property.ReadOnlyObjectProperty; import javafx.collections.ObservableList; import javafx.geometry.Pos; import javafx.scene.Node; import javafx.scene.control.ButtonBar.ButtonData; import javafx.scene.control.ButtonType; +import javafx.scene.control.CheckBox; import javafx.scene.control.ComboBox; import javafx.scene.control.Dialog; import javafx.scene.control.DialogPane; @@ -31,8 +36,7 @@ * {@link #getResult()} when the dialog is dismissed. * @since JavaFX 8u40 */ -@SuppressWarnings("restriction") -public class StyleableChoiceDialog extends Dialog { +public class StyleableContingentChoiceDialog extends Dialog { /************************************************************************** * @@ -45,6 +49,9 @@ public class StyleableChoiceDialog extends Dialog { private final ComboBox comboBox1; private final ComboBox comboBox2; private final T defaultChoice; + private final CheckBox checkboxFilter; + private final Predicate filterPredicate; + /************************************************************************** * @@ -62,9 +69,19 @@ public class StyleableChoiceDialog extends Dialog { * @param defaultChoice The item to display as the pre-selected choice in the dialog. This item * must be contained within the choices varargs array. * @param choices All possible choices to present to the user. + * @param InvalidCoices Choices which, if selected, will disable the "Ok" button + * + * TODO Encapsulate filterName / filterPredicate so they are optional */ - public StyleableChoiceDialog(T defaultChoice, Collection choices, - Multimap secondChoiceMap, Map valueMap) { + public StyleableContingentChoiceDialog(Collection choices, Collection invalidChoices, + Multimap secondChoiceMap, Map valueMap, String filterName, + Predicate filter) { + this(null, choices, invalidChoices, secondChoiceMap, valueMap, filterName, filter); + } + + public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, + Collection invalidChoices, Multimap secondChoiceMap, + Map valueMap, String filterName, Predicate filter) { final DialogPane dialogPane = getDialogPane(); // -- grid @@ -88,14 +105,11 @@ public StyleableChoiceDialog(T defaultChoice, Collection choices, comboBox2 = new ComboBox(); comboBox2.setMinWidth(MIN_WIDTH); - if (choices != null) { - comboBox2.getItems().addAll(choices); - } comboBox2.setMaxWidth(Double.MAX_VALUE); GridPane.setHgrow(comboBox2, Priority.ALWAYS); GridPane.setFillWidth(comboBox2, true); comboBox2.setMaxHeight(10); - comboBox2.getSelectionModel().selectFirst(); + comboBox2.setDisable(true); comboBox1 = new ComboBox(); // comboBox1.setEditable(true); @@ -121,27 +135,56 @@ public StyleableChoiceDialog(T defaultChoice, Collection choices, // // TODO // }); + + this.filterPredicate = filter; + checkboxFilter = new CheckBox(filterName); + checkboxFilter.selectedProperty().addListener((obs, oldV, newV) -> { + T sel1 = comboBox1.getSelectionModel().getSelectedItem(); + T sel2 = comboBox2.getSelectionModel().getSelectedItem(); + + Collection firstChoices = new ArrayList<>(choices); + if (newV) { + firstChoices = firstChoices.stream().filter(filterPredicate).collect(Collectors.toList()); + } + Collection secondChoices = getSecondChoices(secondChoiceMap, sel1, newV); + + comboBox1.getItems().setAll(firstChoices); + + updateSecondComboChoices(secondChoices); + + comboBox1.getSelectionModel().select(sel1); + comboBox2.getSelectionModel().select(sel2); + }); + comboBox1.valueProperty().addListener((obs, oldV, newV) -> { try { - final Collection c = secondChoiceMap.get(newV); + final Collection c = + getSecondChoices(secondChoiceMap, newV, checkboxFilter.isSelected()); - comboBox2.getSelectionModel().clearSelection(); - comboBox2.getItems().setAll(c); - comboBox2.setDisable(c.isEmpty()); - comboBox2.setPromptText(c.isEmpty() ? "No valid pairings found." : null); + updateSecondComboChoices(c); } catch (Throwable t) { - t.printStackTrace(); + throw new RuntimeException(t); } }); this.defaultChoice = comboBox1.getItems().contains(defaultChoice) ? defaultChoice : null; - if (defaultChoice == null) { - comboBox1.getSelectionModel().selectFirst(); - } else { + if (defaultChoice != null) { comboBox1.getSelectionModel().select(defaultChoice); } + Node okButton = dialogPane.lookupButton(ButtonType.OK); + + okButton.disableProperty().bind(Bindings.createBooleanBinding(() -> { + return comboBox2.disableProperty().get() + || invalidChoices.contains(comboBox1.getSelectionModel().getSelectedItem()) + || invalidChoices.contains(comboBox2.getSelectionModel().getSelectedItem()) + || comboBox2.getSelectionModel().isEmpty(); + // for this .isEmpty() call to work, + // the binding must include the + // selectedItemProperty as a dependency + }, comboBox2.disableProperty(), comboBox2.getSelectionModel().selectedItemProperty())); + dialogPane.contentTextProperty().addListener(o -> updateGrid(comboBox1)); updateGrid(comboBox1); @@ -150,6 +193,25 @@ public StyleableChoiceDialog(T defaultChoice, Collection choices, ButtonData data = dialogButton == null ? null : dialogButton.getButtonData(); return data == ButtonData.OK_DONE ? getSelectedItem() : null; }); + + + } + + private void updateSecondComboChoices(final Collection c) { + comboBox2.getSelectionModel().clearSelection(); + comboBox2.getItems().setAll(c); + comboBox2.setDisable(c.isEmpty()); + comboBox2.setPromptText(c.isEmpty() ? "No valid pairings found." : null); + } + + private Collection getSecondChoices(Multimap secondChoiceMap, T newV, boolean filter) { + Collection c = secondChoiceMap.get(newV); + + if (filter) { + c = c.stream().filter(filterPredicate).collect(Collectors.toList()); + } + + return c; } /************************************************************************** @@ -244,10 +306,12 @@ private void updateGrid(Node focusReq) { grid.getChildren().clear(); grid.add(label, 0, 0); - grid.add(comboBox1, 0, 1); - grid.add(comboBox2, 0, 2); + grid.add(checkboxFilter, 0, 1); + grid.add(comboBox1, 0, 2); + grid.add(comboBox2, 0, 3); getDialogPane().setContent(grid); Platform.runLater(() -> focusReq.requestFocus()); } + } diff --git a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java index 4a9d4514..39e00e59 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java +++ b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java @@ -31,6 +31,7 @@ import org.pankratzlab.unet.jfx.DonorNetUtils; import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; +import org.pankratzlab.unet.model.ValidationModelBuilder.ValidationResult; import org.pankratzlab.unet.model.ValidationTable; import org.pankratzlab.unet.parser.DonorFileParser; import org.pankratzlab.unet.parser.HtmlDonorParser; @@ -155,49 +156,36 @@ private void selectDonorFile(ActionEvent event, DonorFileParser donorParser, ValidationModelBuilder builder = new ValidationModelBuilder(); try { + // parse the model donorParser.parseModel(builder, selectedFile); - // building the model may involve user input, so we need to run this on the JavaFX - // Application thread - Platform.runLater(() -> { + // check that the model is valid + ValidationResult validationResult = builder.validate(); - // check that the model is valid - org.pankratzlab.unet.model.ValidationModelBuilder.ValidationResult validationResult = - builder.validate(); + if (!validationResult.valid) { + // if a value is present, show error message + alertInvalid(donorParser, selectedFile, validationResult); + } - if (!validationResult.valid) { + // check for corrections + if (builder.hasCorrectionsIfSoStartLoading()) { - // if a value is present, show error message - if (validationResult.validationMessage.isPresent()) { - Alert alert = new Alert(AlertType.ERROR); - alert.setHeaderText(donorParser.getErrorText() - + "\nPlease notify the developers as this may indicate the data has changed." - + "\nOffending file: " + selectedFile.getName()); - alert.showAndWait(); - } - // either way, invalid model so fail - return; - } - Task buildModelText = JFXUtilHelper.createProgressTask(() -> { - // valid model, build and set - try { - setter.accept(getTable(), builder.build()); - linkedFile.set(selectedFile); - } catch (Throwable e) { - Platform.runLater(() -> { - Alert alert = new Alert(AlertType.ERROR); - alert.setHeaderText(donorParser.getErrorText() - + "\nPlease notify the developers as this may indicate the data has changed." - + "\nOffending file: " + selectedFile.getName()); - alert.showAndWait(); - e.printStackTrace(); - }); + Platform.runLater(() -> { + ValidationResult validationResult1 = builder.processCorrections(); + if (!validationResult1.valid) { + alertInvalid(donorParser, selectedFile, validationResult); + } else { + finish(donorParser, setter, linkedFile, selectedFile, builder); } + }); + } else { + Platform.runLater(() -> { + finish(donorParser, setter, linkedFile, selectedFile, builder); }); - new Thread(buildModelText).start(); - }); + } + } catch (Throwable e) { Platform.runLater(() -> { Alert alert = new Alert(AlertType.ERROR); @@ -216,6 +204,42 @@ private void selectDonorFile(ActionEvent event, DonorFileParser donorParser, } } + private void alertInvalid(DonorFileParser donorParser, File selectedFile, + ValidationResult validationResult) { + if (validationResult.validationMessage.isPresent()) { + Platform.runLater(() -> { + Alert alert = new Alert(AlertType.ERROR); + alert.setHeaderText(donorParser.getErrorText() + + "\nPlease notify the developers as this may indicate the data has changed." + + "\nOffending file: " + selectedFile.getName()); + alert.showAndWait(); + }); + } + } + + private void finish(DonorFileParser donorParser, + BiConsumer setter, ReadOnlyObjectWrapper linkedFile, + File selectedFile, ValidationModelBuilder builder) { + Task buildModelText = JFXUtilHelper.createProgressTask(() -> { + // valid model, build and set + try { + setter.accept(getTable(), builder.build()); + linkedFile.set(selectedFile); + } catch (Throwable e) { + Platform.runLater(() -> { + Alert alert = new Alert(AlertType.ERROR); + alert.setHeaderText(donorParser.getErrorText() + + "\nPlease notify the developers as this may indicate the data has changed." + + "\nOffending file: " + selectedFile.getName()); + alert.showAndWait(); + e.printStackTrace(); + }); + } + + }); + new Thread(buildModelText).start(); + } + /** * The {@link FileInputController#FILE_DISPLAY_CLASS} value links to the * {@link resources/fileInput.css} style-sheet. diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 30fa3c36..7da47758 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -42,11 +42,13 @@ import java.util.Set; import java.util.TreeSet; import java.util.function.Function; +import java.util.function.Predicate; import java.util.function.Supplier; import java.util.stream.Collectors; import javax.swing.JFrame; import javax.swing.JOptionPane; import org.apache.commons.lang3.tuple.Pair; +import org.pankratzlab.BackgroundDataProcessor; import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.NullType; @@ -58,7 +60,7 @@ import org.pankratzlab.unet.hapstats.Haplotype; import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; -import org.pankratzlab.unet.jfx.StyleableChoiceDialog; +import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog; import org.pankratzlab.unet.parser.util.BwSerotypes; import org.pankratzlab.unet.parser.util.BwSerotypes.BwGroup; import org.pankratzlab.unet.parser.util.DRAssociations; @@ -128,6 +130,9 @@ public class ValidationModelBuilder { private Set aLocusFirst = new LinkedHashSet<>(); private Set bLocusFirst = new LinkedHashSet<>(); private Set cLocusFirst = new LinkedHashSet<>(); + private Set aLocusFirstTypes; + private Set bLocusFirstTypes; + private Set cLocusFirstTypes; private Map possibleAllelePairings = new HashMap<>(); private Map donorAllelePairings = new HashMap<>(); @@ -146,6 +151,11 @@ public class ValidationModelBuilder { private Set dpaLocusTypes; private Set dpbLocusTypes; + private Set dqaLocusTypesNonCWD; + private Set dqbLocusTypesNonCWD; + private Set dpaLocusTypesNonCWD; + private Set dpbLocusTypesNonCWD; + private Set drbLocusNonCWD; private Set dqaLocusNonCWD; private Set dqbLocusNonCWD; @@ -197,6 +207,12 @@ public ValidationModelBuilder aType(HLAType aType) { return this; } + public ValidationModelBuilder aTypeNonCWD(HLAType aType) { + aLocusFirstTypes = makeIfNull(aLocusFirstTypes); + addToLocus(aLocusFirstTypes, HLALocus.A, aType); + return this; + } + public ValidationModelBuilder aNonCWD(String aType) { if (test1(aType)) { return null; @@ -221,6 +237,11 @@ public ValidationModelBuilder bType(HLAType bType) { return this; } + public ValidationModelBuilder bTypeNonCWD(HLAType bType) { + bLocusFirstTypes = makeIfNull(bLocusFirstTypes); + addToLocus(bLocusFirstTypes, HLALocus.B, bType); + return this; + } public ValidationModelBuilder bNonCWD(String bType) { if (test1(bType)) { @@ -246,6 +267,11 @@ public ValidationModelBuilder cType(HLAType cType) { return this; } + public ValidationModelBuilder cTypeNonCWD(HLAType cType) { + cLocusFirstTypes = makeIfNull(cLocusFirstTypes); + addToLocus(cLocusFirstTypes, HLALocus.C, cType); + return this; + } public ValidationModelBuilder cNonCWD(String cType) { if (test1(cType)) { @@ -414,6 +440,15 @@ public ValidationModelBuilder dqbType(HLAType dqbType) { return this; } + public ValidationModelBuilder dqbTypeNonCWD(HLAType dqbType) { + if (test2(dqbType)) { + return null; + } + dqbLocusTypesNonCWD = makeIfNull(dqbLocusTypesNonCWD); + addToLocus(dqbLocusTypesNonCWD, HLALocus.DQB1, dqbType); + return this; + } + public ValidationModelBuilder dqaType(HLAType dqaType) { if (test2(dqaType)) { return null; @@ -423,6 +458,15 @@ public ValidationModelBuilder dqaType(HLAType dqaType) { return this; } + public ValidationModelBuilder dqaTypeNonCWD(HLAType dqaType) { + if (test2(dqaType)) { + return null; + } + dqaLocusTypesNonCWD = makeIfNull(dqaLocusTypesNonCWD); + addToLocus(dqaLocusTypesNonCWD, HLALocus.DQA1, dqaType); + return this; + } + public ValidationModelBuilder dpaType(HLAType dpaType) { if (test2(dpaType)) { return null; @@ -432,6 +476,15 @@ public ValidationModelBuilder dpaType(HLAType dpaType) { return this; } + public ValidationModelBuilder dpaTypeNonCWD(HLAType dpaType) { + if (test2(dpaType)) { + return null; + } + dpaLocusTypesNonCWD = makeIfNull(dpaLocusTypesNonCWD); + addToLocus(dpaLocusTypesNonCWD, HLALocus.DPA1, dpaType); + return this; + } + private boolean test2(HLAType dqbType) { return dqbType == null; } @@ -513,7 +566,7 @@ private AlleleStringConverter(PresentableAlleleChoices choices) { @Override public String toString(Supplier object) { - final String selectedData = choices.getSelectedData(object); + final String selectedData = choices.getData(object); return selectedData == null ? "" : selectedData; } @@ -915,137 +968,187 @@ private ValidationResult ensureValidity() { Collections.sort(dr52Locus); Collections.sort(dr53Locus); - if (!nonCWDLoci.isEmpty()) { - for (HLALocus locus : nonCWDLoci) { - - Set locusSet; - Set typesSet; - AllelePairings allelePairs = possibleAllelePairings.get(locus); - AllelePairings donorPairs = donorAllelePairings.get(locus); - - switch (locus) { - case A: - locusSet = aLocusCWD; - typesSet = aLocusCWDTypes; - break; - case B: - locusSet = bLocusCWD; - typesSet = bLocusCWDTypes; - break; - case C: - locusSet = cLocusCWD; - typesSet = cLocusCWDTypes; - break; - case DPA1: - locusSet = dpaLocus; - typesSet = dpaLocusTypes; - break; - case DQA1: - locusSet = dqaLocus; - typesSet = dqaLocusTypes; - break; - case DPB1: - locusSet = null; - typesSet = dpbLocusTypes; - case DQB1: - locusSet = dqbLocus; - typesSet = dqbLocusTypes; - default: - allelePairs = null; - donorPairs = null; - locusSet = null; - typesSet = null; - break; - } - if (allelePairs == null || donorPairs == null) { - // TODO - continue; - } - - Iterator iter = locusSet == null ? null : locusSet.iterator(); - String header = "Assigned allele pair (" + typesSet.stream().map(ht -> { - return (iter == null ? "" : (iter.next()) + " / ") + ht.specString() + " - " - + CommonWellDocumented.getEquivStatus(ht); - }).collect(Collectors.joining(", ")) + ") for HLA-" + locus.name() - + " locus is not Common / Well-Documented."; - - String text = - "Please select desired allele pair for this locus. Selecting the first allele will populate valid pairings for the second allele."; - - PresentableAlleleChoices choices = PresentableAlleleChoices.create(allelePairs); - - final List> allChoices = choices.getAllChoices(); - - Function, String> tooltipProvider = (tf) -> { - return Objects.toString(choices.dataMap.get(tf), null); - }; + return new ValidationResult(true, Optional.empty()); + } - StyleableChoiceDialog> cd = new StyleableChoiceDialog<>( - allChoices.get(0), allChoices, choices.getAllSecondChoices(), choices.dataMap); - cd.setTitle("Select HLA-" + locus.name() + " Alleles"); - cd.setHeaderText(header); - cd.setContentText(text); - cd.setCombo1CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo1ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo2CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo2ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); - cd.setConverter1(new AlleleStringConverter(choices)); - cd.setConverter2(new AlleleStringConverter(choices)); + BackgroundDataProcessor choiceSupplier; - Optional> result = cd.showAndWait(); + public boolean hasCorrectionsIfSoStartLoading() { + if (!nonCWDLoci.isEmpty()) { + // start loading data in the background + choiceSupplier = new BackgroundDataProcessor<>(nonCWDLoci, + (locus) -> PresentableAlleleChoices.create(locus, getAllelePairs(locus)), (t) -> { + t.printStackTrace(); + return null; + }); + return true; + } + return false; + } + + public ValidationResult processCorrections() { + + for (HLALocus locus : nonCWDLoci) { + AllelePairings allelePairs = possibleAllelePairings.get(locus); + AllelePairings donorPairs = donorAllelePairings.get(locus); + + Set locusSet; + Set locusSetNonCWD; + Set typesSet; + Set typesSetNonCWD; + + // TODO replace this switch-statement with OOP design somehow... + switch (locus) { + case A: + locusSet = aLocusCWD; + locusSetNonCWD = aLocusFirst; + typesSet = aLocusCWDTypes; + typesSetNonCWD = aLocusFirstTypes; + break; + case B: + locusSet = bLocusCWD; + locusSetNonCWD = bLocusFirst; + typesSet = bLocusCWDTypes; + typesSetNonCWD = bLocusFirstTypes; + break; + case C: + locusSet = cLocusCWD; + locusSetNonCWD = cLocusFirst; + typesSet = cLocusCWDTypes; + typesSetNonCWD = cLocusFirstTypes; + break; + case DPA1: + locusSet = dpaLocus; + locusSetNonCWD = dpaLocusNonCWD; + typesSet = dpaLocusTypes; + typesSetNonCWD = dpaLocusTypesNonCWD; + break; + case DQA1: + locusSet = dqaLocus; + locusSetNonCWD = dqaLocusNonCWD; + typesSet = dqaLocusTypes; + typesSetNonCWD = dqaLocusTypesNonCWD; + break; + case DPB1: + locusSet = null; + locusSetNonCWD = dpbLocusNonCWD.stream().map(HLAType::equivSafe) + .collect(ImmutableSet.toImmutableSet()); + typesSet = dpbLocusTypes; + typesSetNonCWD = dpbLocusTypesNonCWD; + case DQB1: + locusSet = dqbLocus; + locusSetNonCWD = dqbLocusNonCWD; + typesSet = dqbLocusTypes; + typesSetNonCWD = dqbLocusTypesNonCWD; + default: + allelePairs = null; + donorPairs = null; + locusSet = null; + locusSetNonCWD = null; + typesSet = null; + typesSetNonCWD = null; + break; + } + if (allelePairs == null || donorPairs == null) { + // TODO + continue; + } - if (!result.isPresent()) { - return new ValidationResult(false, Optional.empty()); - } + Iterator iter = locusSetNonCWD == null ? null : locusSetNonCWD.iterator(); + String header = "Assigned allele pair (" + typesSetNonCWD.stream().map(ht -> { + return (iter == null ? "" : (iter.next()) + " / ") + ht.specString() + " - " + + CommonWellDocumented.getEquivStatus(ht); + }).collect(Collectors.joining(", ")) + ") for HLA-" + locus.name() + + " locus is not Common / Well-Documented."; + + String text = + "Please select desired allele pair for this locus. Selecting the first allele will populate valid pairings for the second allele."; + + // FIXME TODO this needs to be done on a Task thread to show a progress spinner if it blocks + // while loading. However, the choice dialogs need to be created on the JavaFX thread. + // But also, this method overall needs to return a single validation result object ... + PresentableAlleleChoices choices = choiceSupplier.get(locus); + + final List> allChoices = choices.getAllChoices(); + + Function, String> tooltipProvider = (tf) -> { + return Objects.toString(choices.dataMap.get(tf), null); + }; + + String filterName = "Show CIWD Alleles Only"; + Predicate> filter = (tf) -> { + return isAnyPartCWD(choices.getData(tf)); + }; + + StyleableContingentChoiceDialog> cd = + new StyleableContingentChoiceDialog<>(allChoices, Lists.newArrayList(), + choices.getAllSecondChoices(), choices.dataMap, filterName, filter); + cd.setTitle("Select HLA-" + locus.name() + " Alleles"); + cd.setHeaderText(header); + cd.setContentText(text); + cd.setCombo1CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo1ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo2CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo2ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); + cd.setConverter1(new AlleleStringConverter(choices)); + cd.setConverter2(new AlleleStringConverter(choices)); + + Optional> result = cd.showAndWait(); + + if (!result.isPresent()) { + return new ValidationResult(false, Optional.empty()); + } - Supplier selAllele1 = result.get(); - Supplier selAllele2 = cd.getSelectedSecondItem(); + Supplier selAllele1 = result.get(); + Supplier selAllele2 = cd.getSelectedSecondItem(); - String allele1 = choices.getSelectedData(selAllele1); - String allele2 = choices.getSelectedData(selAllele2); + String allele1 = choices.getData(selAllele1); + String allele2 = choices.getData(selAllele2); - HLAType hlaType1 = HLAType.valueOf(allele1); - HLAType hlaType2 = HLAType.valueOf(allele2); - SeroType seroType1 = hlaType1.equivSafe(); - SeroType seroType2 = hlaType2.equivSafe(); + HLAType hlaType1 = HLAType.valueOf(allele1); + HLAType hlaType2 = HLAType.valueOf(allele2); + SeroType seroType1 = hlaType1.equivSafe(); + SeroType seroType2 = hlaType2.equivSafe(); - final Iterator typeIter = typesSet.iterator(); - HLAType hlaType1Old = typeIter.next(); - HLAType hlaType2Old = typeIter.hasNext() ? typeIter.next() : hlaType1Old; + final Iterator typeIter = typesSet.iterator(); + HLAType hlaType1Old = typeIter.next(); + HLAType hlaType2Old = typeIter.hasNext() ? typeIter.next() : hlaType1Old; - final Iterator seroIter = locusSet.iterator(); - SeroType seroType1Old = seroIter.next(); - SeroType seroType2Old = seroIter.hasNext() ? seroIter.next() : seroType1Old; + final Iterator seroIter = locusSet.iterator(); + SeroType seroType1Old = seroIter.next(); + SeroType seroType2Old = seroIter.hasNext() ? seroIter.next() : seroType1Old; - locusSet.clear(); - locusSet.add(seroType1); - locusSet.add(seroType2); - typesSet.clear(); - typesSet.add(hlaType1); - typesSet.add(hlaType2); + locusSet.clear(); + locusSet.add(seroType1); + locusSet.add(seroType2); + typesSet.clear(); + typesSet.add(hlaType1); + typesSet.add(hlaType2); - boolean a1Match = - hlaType1.compareTo(hlaType1Old) == 0 || hlaType1.compareTo(hlaType2Old) == 0; - boolean a2Match = - hlaType2.compareTo(hlaType1Old) == 0 || hlaType2.compareTo(hlaType2Old) == 0; + boolean a1Match = + hlaType1.compareTo(hlaType1Old) == 0 || hlaType1.compareTo(hlaType2Old) == 0; + boolean a2Match = + hlaType2.compareTo(hlaType1Old) == 0 || hlaType2.compareTo(hlaType2Old) == 0; - if (!a1Match || !a2Match) { - ImmutableSortedSet prevSet = ImmutableSortedSet - .of(new TypePair(hlaType1Old, seroType1Old), new TypePair(hlaType2Old, seroType2Old)); + if (!a1Match || !a2Match) { + ImmutableSortedSet prevSet = ImmutableSortedSet + .of(new TypePair(hlaType1Old, seroType1Old), new TypePair(hlaType2Old, seroType2Old)); - ImmutableSortedSet newSet = ImmutableSortedSet - .of(new TypePair(hlaType1, seroType1), new TypePair(hlaType2, seroType2)); + ImmutableSortedSet newSet = ImmutableSortedSet + .of(new TypePair(hlaType1, seroType1), new TypePair(hlaType2, seroType2)); - remapping.put(locus, Pair.of(prevSet, newSet)); - } + remapping.put(locus, Pair.of(prevSet, newSet)); } - } return new ValidationResult(true, Optional.empty()); } + private AllelePairings getAllelePairs(HLALocus locus) { + return possibleAllelePairings.get(locus); + } + public abstract static class PresentableDataChoices { List choices; Multimap secondChoices; @@ -1072,8 +1175,12 @@ public Collection getSecondChoices(T firstChoice) { public abstract List getMatchingChoices(String userInput); - public R getSelectedData(T selected) { - return dataMap.get(selected); + public R getData(T presentable) { + return dataMap.get(presentable); + } + + public T getPresentation(R data) { + return dataMap.inverse().get(data); } } @@ -1081,14 +1188,13 @@ public R getSelectedData(T selected) { public static class PresentableAlleleChoices extends PresentableDataChoices, String> { - public static PresentableAlleleChoices create(AllelePairings allelePairings) { + public static PresentableAlleleChoices create(HLALocus locus, AllelePairings allelePairings) { + List> userChoices = new ArrayList<>(); ListMultimap, Supplier> secondChoices = SortedSetMultimapBuilder.hashKeys().arrayListValues().build(); BiMap, String> presentationToDataMap = HashBiMap.create(); - userChoices.add(() -> new TextFlow()); - List alleleKeys = new ArrayList<>(allelePairings.map.keySet()); sortAlleleStrings(alleleKeys); @@ -1101,6 +1207,7 @@ public static PresentableAlleleChoices create(AllelePairings allelePairings) { presentationToDataMap.put(supp, allele); } + for (Supplier choice : userChoices) { String data = presentationToDataMap.get(choice); if (data == null) { @@ -1129,13 +1236,14 @@ public static PresentableAlleleChoices create(AllelePairings allelePairings) { private static List condenseIntoGroups(AllelePairings allelePairings, List alleleKeys, boolean checkPairings) { + List> subsets = new ArrayList<>(); List subset = new ArrayList<>(); HLAType prev3FieldType = null; // all allele strings should be in the correct order now - // now let's condense into subsets of the same allele types, with + // now let's condense into subsets of the same serotypes, with // separate subsets for N/n and LSCAQ/lscaq alleles for (String allele : alleleKeys) { if (allele.matches(NOT_EXPRESSED) || allele.matches(NOT_ON_CELL_SURFACE)) { @@ -1259,8 +1367,8 @@ private static void sortAlleleStrings(List alleleKeys) { boolean check2C = s2.matches(NOT_ON_CELL_SURFACE); boolean check1 = check1N || check1C; boolean check2 = check2N || check2C; - char s1C = s1.charAt(s1.length() - 1); - char s2C = s2.charAt(s2.length() - 1); + // char s1C = s1.charAt(s1.length() - 1); + // char s2C = s2.charAt(s2.length() - 1); String s1Hs = check1 ? s1.substring(0, s1.length() - 1) : s1; String s2Hs = check2 ? s2.substring(0, s2.length() - 1) : s2; @@ -1333,11 +1441,11 @@ private static TextFlow getText(String allele) { List textNodes = new ArrayList<>(); if (allele.contains("-")) { String[] a = allele.split("-"); - addTextNodes(textNodes, a[0]); - textNodes.add(new Text("-")); - addTextNodes(textNodes, a[1]); + addTextNodes(textNodes, a[0], false); + textNodes.add(new Text(" - ")); + addTextNodes(textNodes, a[1], true); } else { - addTextNodes(textNodes, allele); + addTextNodes(textNodes, allele, true); } Text[] nodes = textNodes.toArray(new Text[textNodes.size()]); @@ -1345,7 +1453,14 @@ private static TextFlow getText(String allele) { return tf; } - private static void addTextNodes(List textNodes, final String allele) { + private boolean isAnyPartCWD(String allele) { + HLAType alleleType = HLAType.valueOf(allele); + Status status1 = CommonWellDocumented.getStatus(alleleType); + + return status1 != Status.UNKNOWN; + } + + private static void addTextNodes(List textNodes, final String allele, boolean addSero) { HLAType alleleType = HLAType.valueOf(allele); HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); Status status1 = CommonWellDocumented.getStatus(alleleType); @@ -1377,8 +1492,10 @@ private static void addTextNodes(List textNodes, final String allele) { .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); } - textNodes.add( - new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); + if (addSero) { + textNodes.add( + new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); + } } private static class SimpleTableObjectListCell extends ListCell> { diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java index ab031478..cbbbea14 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java @@ -105,6 +105,7 @@ public class XmlScore6Parser { private static ImmutableMap> metadataMap; private static ImmutableMap> metadataTypeMap; private static ImmutableMap> metadataNonCWDMap; + private static ImmutableMap> metadataTypeNonCWDMap; private static ImmutableMap> possibleAlleleRecordingMap; private static ImmutableMap> donorAlleleRecordingMap; private static ImmutableMap> drbMap; @@ -157,6 +158,29 @@ private static void init() { metadataTypeMap = setterBuilderTypes.build(); + // -- Build mapping bemetadataTypeMaptween loci sections, serotype prefixes and validation model + // setters -- + Builder> setterBuilderTypesNonCWD = + ImmutableMap.builder(); + setterBuilderTypesNonCWD.put(A_HEADER, ValidationModelBuilder::aTypeNonCWD); + setterBuilderTypesNonCWD.put(B_HEADER, ValidationModelBuilder::bTypeNonCWD); + setterBuilderTypesNonCWD.put(C_HEADER, ValidationModelBuilder::cTypeNonCWD); + setterBuilderTypesNonCWD.put(DQB_HEADER, ValidationModelBuilder::dqbTypeNonCWD); + + // Reported as allele types + // DPB is already being tracked as HLATypes + // setterBuilderTypes.put(DPB_HEADER, ValidationModelBuilder::dpbType); + setterBuilderTypesNonCWD.put(DQA_HEADER, ValidationModelBuilder::dqaTypeNonCWD); + setterBuilderTypesNonCWD.put(DPA_HEADER, ValidationModelBuilder::dpaTypeNonCWD); + + // DR52/53/54 appears as a serological combination + // setterBuilderTypes.put(DRB_HEADER, ValidationModelBuilder::drbType); + + // NB: not in DonorNet + // setterBuilder.put("HLA-DPA1", null); + + metadataTypeNonCWDMap = setterBuilderTypesNonCWD.build(); + // -- Build mapping between loci sections, serotype prefixes and validation model setters -- Builder> setterBuilderNonCWD = ImmutableMap.builder(); @@ -444,12 +468,13 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo // Finally, add the types to the model builder for (int i = 0; i < actualResultPairs.size(); i++) { - if (actualResultPairs.get(i).alleleCombination - .compareTo(firstResultPairs.get(0).alleleCombination) != 0) { - Status sA = CommonWellDocumented.getStatus(actualResultPairs.get(i).alleleCombination); - Status sF = CommonWellDocumented.getStatus(firstResultPairs.get(i).alleleCombination); + final HLAType alleleCombination = actualResultPairs.get(i).alleleCombination; + final HLAType alleleCombination2 = firstResultPairs.get(i).alleleCombination; + if (alleleCombination.compareTo(alleleCombination2) != 0) { + Status sA = CommonWellDocumented.getStatus(alleleCombination); + Status sF = CommonWellDocumented.getStatus(alleleCombination2); if (sA == Status.UNKNOWN || sF == Status.UNKNOWN) { - builder.locusIsNonCIWD(actualResultPairs.get(i).alleleCombination); + builder.locusIsNonCIWD(alleleCombination); } } @@ -462,7 +487,10 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo metadataNonCWDMap.get(locus).accept(builder, specStringFirst); } if (metadataTypeMap.containsKey(locus)) { - metadataTypeMap.get(locus).accept(builder, actualResultPairs.get(i).alleleCombination); + metadataTypeMap.get(locus).accept(builder, alleleCombination); + } + if (metadataTypeNonCWDMap.containsKey(locus)) { + metadataTypeNonCWDMap.get(locus).accept(builder, alleleCombination2); } } From b8f06a4a777c5032e997d70bfe4c58d644b60f0f Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Wed, 8 May 2024 15:34:51 -0500 Subject: [PATCH 04/23] Change StyleableContingentChoiceDialog to have two filter checkboxes --- .../jfx/StyleableContingentChoiceDialog.java | 83 +++++++++---------- 1 file changed, 40 insertions(+), 43 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index b69b0cdc..e9551068 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -1,6 +1,5 @@ package org.pankratzlab.unet.jfx; -import java.util.ArrayList; import java.util.Collection; import java.util.Map; import java.util.function.Predicate; @@ -10,6 +9,7 @@ import javafx.application.Platform; import javafx.beans.binding.Bindings; import javafx.beans.property.ReadOnlyObjectProperty; +import javafx.collections.FXCollections; import javafx.collections.ObservableList; import javafx.geometry.Pos; import javafx.scene.Node; @@ -49,7 +49,8 @@ public class StyleableContingentChoiceDialog extends Dialog { private final ComboBox comboBox1; private final ComboBox comboBox2; private final T defaultChoice; - private final CheckBox checkboxFilter; + private final CheckBox checkboxFilter1; + private final CheckBox checkboxFilter2; private final Predicate filterPredicate; @@ -122,46 +123,22 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, GridPane.setFillWidth(comboBox1, true); comboBox1.setMaxHeight(10); - // comboBox1.setOnKeyTyped((kv) -> { - // try { - // comboBox1.getEditor().getText(); - // comboBox1.getItems().clear(); - // - // comboBox1.getItems().addAll(choices); - // comboBox1.show(); - // } catch (Throwable t) { - // t.printStackTrace(); - // } - // // TODO - // }); - - this.filterPredicate = filter; - checkboxFilter = new CheckBox(filterName); - checkboxFilter.selectedProperty().addListener((obs, oldV, newV) -> { - T sel1 = comboBox1.getSelectionModel().getSelectedItem(); - T sel2 = comboBox2.getSelectionModel().getSelectedItem(); - - Collection firstChoices = new ArrayList<>(choices); - if (newV) { - firstChoices = firstChoices.stream().filter(filterPredicate).collect(Collectors.toList()); - } - Collection secondChoices = getSecondChoices(secondChoiceMap, sel1, newV); - comboBox1.getItems().setAll(firstChoices); + checkboxFilter1 = new CheckBox(filterName); + checkboxFilter2 = new CheckBox(filterName); - updateSecondComboChoices(secondChoices); - - comboBox1.getSelectionModel().select(sel1); - comboBox2.getSelectionModel().select(sel2); - }); + checkboxFilter1.selectedProperty() + .addListener((obs, oldV, newV) -> updateFirstComboChoices(newV, choices)); + checkboxFilter2.selectedProperty() + .addListener((obs, oldV, newV) -> updateSecondComboState(secondChoiceMap, newV)); comboBox1.valueProperty().addListener((obs, oldV, newV) -> { try { - final Collection c = - getSecondChoices(secondChoiceMap, newV, checkboxFilter.isSelected()); - - updateSecondComboChoices(c); + Collection c = getSecondChoices(secondChoiceMap, newV, checkboxFilter2.isSelected()); + comboBox2.getSelectionModel().clearSelection(); + comboBox2.getItems().setAll(c); + comboBox2.setDisable(c.isEmpty()); } catch (Throwable t) { throw new RuntimeException(t); } @@ -197,11 +174,30 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, } - private void updateSecondComboChoices(final Collection c) { - comboBox2.getSelectionModel().clearSelection(); - comboBox2.getItems().setAll(c); - comboBox2.setDisable(c.isEmpty()); - comboBox2.setPromptText(c.isEmpty() ? "No valid pairings found." : null); + private void updateFirstComboChoices(boolean filterActive, Collection choices) { + ObservableList filteredChoices = + choices.stream().filter(item -> !filterActive || filterPredicate.test(item)) + .collect(Collectors.toCollection(FXCollections::observableArrayList)); + comboBox1.setItems(filteredChoices); + if (!filteredChoices.contains(comboBox1.getSelectionModel().getSelectedItem())) { + comboBox1.getSelectionModel().clearSelection(); + } + } + + + private void updateSecondComboState(Multimap secondChoiceMap, boolean filterActive) { + T selectedFirstItem = comboBox1.getSelectionModel().getSelectedItem(); + ObservableList secondChoices = + FXCollections.observableArrayList(secondChoiceMap.get(selectedFirstItem)); + if (filterActive) { + secondChoices = secondChoices.stream().filter(filterPredicate) + .collect(Collectors.toCollection(FXCollections::observableArrayList)); + } + comboBox2.setItems(secondChoices); + comboBox2.setDisable(secondChoices.isEmpty()); + if (!secondChoices.contains(comboBox2.getSelectionModel().getSelectedItem())) { + comboBox2.getSelectionModel().clearSelection(); + } } private Collection getSecondChoices(Multimap secondChoiceMap, T newV, boolean filter) { @@ -306,9 +302,10 @@ private void updateGrid(Node focusReq) { grid.getChildren().clear(); grid.add(label, 0, 0); - grid.add(checkboxFilter, 0, 1); + grid.add(checkboxFilter1, 0, 1); grid.add(comboBox1, 0, 2); - grid.add(comboBox2, 0, 3); + grid.add(checkboxFilter2, 0, 3); + grid.add(comboBox2, 0, 4); getDialogPane().setContent(grid); Platform.runLater(() -> focusReq.requestFocus()); From 39444430348255e4faf5e835ab9073b0d3525c7a Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Tue, 21 May 2024 14:12:26 -0500 Subject: [PATCH 05/23] temp --- .../unet/deprecated/hla/Antigen.java | 13 +- .../deprecated/hla/AntigenDictionary.java | 11 +- .../unet/deprecated/hla/HLAType.java | 93 ++- .../unet/hapstats/CommonWellDocumented.java | 96 +-- .../jfx/StyleableContingentChoiceDialog.java | 238 +++++--- .../unet/jfx/wizard/FileInputController.java | 2 + .../unet/model/DRDQHaplotypeRow.java | 15 +- .../unet/model/ValidationModelBuilder.java | 569 +++++++++--------- .../unet/parser/util/SerotypeEquivalence.java | 50 +- 9 files changed, 629 insertions(+), 458 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java index c3fe0719..60eff7d0 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java @@ -2,7 +2,7 @@ * #%L * DonorCheck * %% - * Copyright (C) 2018 - 2019 Computational Pathology - University of Minnesota + * Copyright (C) 2018 - 2024 Computational Pathology - University of Minnesota * %% * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as @@ -39,7 +39,6 @@ import java.util.regex.Matcher; import java.util.regex.Pattern; import java.util.stream.Collectors; - import com.google.common.collect.ImmutableList; import com.google.common.primitives.Ints; @@ -232,7 +231,7 @@ private List parse(String[] p) { int[] iVal = new int[1]; Matcher matcher = SPEC_PATTERN.matcher(spec); matcher.find(); - // Extracts value from parents if they were present + // Extracts value from parentheses if they were present String val = matcher.group(2) != null ? matcher.group(2) : matcher.group(1); if (val.contains(SPEC_DELIM)) { @@ -240,8 +239,12 @@ private List parse(String[] p) { return parse(val.split(SPEC_DELIM)); } // "0105" should be "01:05" - if (val.length() > 2 && val.charAt(0) == '0') { - return parse(new String[] {spec.substring(0, 2), spec.substring(2)}); + if (val.length() > 2) { + if (val.charAt(0) == '0') { + return parse(new String[] {spec.substring(0, 2), spec.substring(2)}); + } else { + // System.out.println(); + } } iVal[0] = Integer.parseInt(val); return parse(iVal); diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java index b5b7d227..2a28dcb1 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java @@ -31,7 +31,7 @@ import java.nio.file.Files; import java.nio.file.Paths; import java.util.ArrayList; -import java.util.HashSet; +import java.util.LinkedHashSet; import java.util.List; import java.util.Set; import java.util.concurrent.Callable; @@ -45,11 +45,7 @@ /** Persistent map of {@link HLAType}s to equivalent {@link SeroType}s. Use when converting. */ public final class AntigenDictionary implements Serializable { - private static final long serialVersionUID = 10L; - - public static final int LATEST_REVISION = - 1 + HLAType.LATEST_REVISION + SeroType.LATEST_REVISION + Antigen.LATEST_REVISION; - private int revision = LATEST_REVISION; + private static final long serialVersionUID = 11L; public static final String REL_DNA_SER_PROP = "rel.dna.ser.file"; @@ -178,6 +174,7 @@ private static void parseDictionaries(Callable readerSupplier) { } ImmutableSetMultimap.Builder hlaBuilder = ImmutableSetMultimap.builder(); ImmutableSetMultimap.Builder seroBuilder = ImmutableSetMultimap.builder(); + // NB: what's considered a valid HLA type diverges from the HLA map keyset and thus must be // tracked separately Builder validHLATypes = ImmutableSet.builder(); @@ -208,7 +205,7 @@ private static void parseDictionaries(Callable readerSupplier) { // Parse out the serological specificities for this mapping // Since the columns are ordered by specificity, we use the first column with valid entries - Set seroSpecs = new HashSet<>(); + Set seroSpecs = new LinkedHashSet<>(); for (int i = 2; i <= 5 && i < columns.length; i++) { String types = columns[i]; // Each HLA type may map to multiple serotypes diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/HLAType.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/HLAType.java index 343ba6e1..cb77694b 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/HLAType.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/HLAType.java @@ -21,7 +21,9 @@ */ package org.pankratzlab.unet.deprecated.hla; +import java.util.ArrayList; import java.util.Arrays; +import java.util.HashSet; import java.util.LinkedHashSet; import java.util.List; import java.util.Set; @@ -29,7 +31,6 @@ import java.util.regex.Matcher; import java.util.regex.Pattern; import java.util.stream.Collectors; - import com.google.common.primitives.Ints; /** {@link Antigen} implementation for HLA antigens */ @@ -85,27 +86,54 @@ public HLAType(HLALocus l, List p) { * Note: this method is similar to {@link AntigenDictionary#lookup(HLAType)}, with two exceptions: * *
    - *
  • In the case of multiple {@link SeroType} mappings, only the first will be returned + *
  • In the case of multiple {@link SeroType} mappings, only the first will be returned *
  • If there is no explicit mapping for this type, a {@code SeroType} will be created using the * equivalent {@link SeroLocus} and the first value in this type's {@link #spec()} *
* - * @return {@link SeroType} equivalent of this antigen - * @throws IllegalStateException If this type has ambiguous serotype equivalencies + * @return {@link SeroType} equivalent of this antigen
+ *
+ * */ public SeroType equiv() { + Set lookup = new HashSet<>(); try { - Set lookup = AntigenDictionary.lookup(this); - if (lookup.size() == 1) { - return lookup.iterator().next(); - } else if (lookup.size() > 1) { - throw new IllegalStateException( - "HLA type: " + this + " has multiple serotype equivalencies"); - } + lookup = AntigenDictionary.lookup(this); } catch (IllegalArgumentException e) { + if (this.resolution() < 3) { + // grow spec with 01s until a mapping (if any) is found) + HLAType t = this; + while (t != null && lookup.isEmpty()) { + t = growSpec(t); + try { + lookup = AntigenDictionary.lookup(t); + } catch (IllegalArgumentException e2) { + // might not need this + lookup = new HashSet<>(); + } + } + } else if (this.resolution() > 2) { + // reduce spec by removing any 01s + HLAType t = this; + while (t != null && lookup.isEmpty()) { + t = reduceSpec(t); + try { + lookup = AntigenDictionary.lookup(t); + } catch (IllegalArgumentException e2) { + // might not need this + lookup = new HashSet<>(); + } + } + } // No-op } + if (lookup.size() == 1) { + return lookup.iterator().next(); + } else if (lookup.size() > 1) { + return lookup.iterator().next(); + } + // If we don't have an explicit mapping of this HLAType, just use the first spec return lowResEquiv(); } @@ -148,6 +176,49 @@ protected List parse(int[] p) { return values; } + /** + * @param equivType Input type to reduce + * @return The input {@link HLAType} with its tailing "01" field removed, or null if the allele + * can not be reduced + */ + public static HLAType reduceSpec(HLAType equivType) { + List spec = equivType.spec(); + + if (spec.size() < 2 || (spec.size() < 4 && spec.get(spec.size() - 1) != 1)) { + // We can only remove a trailing "01 "specificity, and only if we have 3- or more fields + return null; + } + + spec = spec.subList(0, spec.size() - 1); + return HLAType.modifiedSpec(equivType, spec); + } + + /** + * @param equivType Input type to expand + * @return The input {@link HLAType} with an additional "01" field, or null if the allele can not + * be further expanded + */ + public static HLAType growSpec(HLAType equivType) { + List spec = new ArrayList<>(equivType.spec()); + + if (spec.size() >= 4) { + // We can only expand 2- and 3-field specificities + return null; + } + + spec.add(1); + + return HLAType.modifiedSpec(equivType, spec); + } + + /** Helper method to create an updated HLAType */ + private static HLAType modifiedSpec(HLAType equivType, List spec) { + if (equivType instanceof NullType) { + return new NullType(equivType.locus(), spec); + } + return new HLAType(equivType.locus(), spec); + } + /** @see Antigen#is(String, Pattern) */ public static boolean is(String text) { return Antigen.is(text, TYPE_PATTERN); diff --git a/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java b/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java index 1646b753..9f64bacd 100644 --- a/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java +++ b/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java @@ -24,7 +24,6 @@ import java.io.BufferedReader; import java.io.InputStream; import java.io.InputStreamReader; -import java.util.ArrayList; import java.util.HashMap; import java.util.List; import java.util.Map; @@ -36,7 +35,6 @@ import org.jsoup.select.Elements; import org.pankratzlab.unet.deprecated.hla.HLAProperties; import org.pankratzlab.unet.deprecated.hla.HLAType; -import org.pankratzlab.unet.deprecated.hla.NullType; import org.pankratzlab.unet.parser.XmlDonorParser; import com.google.common.cache.CacheBuilder; import com.google.common.cache.CacheLoader; @@ -144,32 +142,37 @@ public static void init() { cd.setContentText("You may change this selection from the DonorCheck menu bar."); Optional result = cd.showAndWait(); result.ifPresent(r -> { - try { - switch (r) { - case CWD_200: - loadCWD200(); - break; - case CIWD_300: - loadCIWD300(); - break; - default: - break; - } - - // save the selected value - HLAProperties.get().setProperty(CWD_PROP, r.name()); - - } catch (Exception e) { - e.printStackTrace(); - } + loadCIWDVersion(r); }); if (!result.isPresent()) { - throw new IllegalStateException("CWD DB must be selected"); + // user cancelled, load previous/default version + loadCIWDVersion(def); } } + private static void loadCIWDVersion(SOURCE r) { + try { + switch (r) { + case CWD_200: + loadCWD200(); + break; + case CIWD_300: + loadCIWD300(); + break; + default: + break; + } + + // save the selected value + HLAProperties.get().setProperty(CWD_PROP, r.name()); + + } catch (Exception e) { + e.printStackTrace(); + } + } + public static void loadCWD200() { // -- Read allele frequency map -- try (InputStream htmlStream = XmlDonorParser.class.getResourceAsStream(ALLELE_FREQ_PATH_200)) { @@ -278,7 +281,7 @@ public static HLAType getCWDType(HLAType type) { // adding or removing trailing :01's does not change the allele specificity // Try adding :01's to the specificity HLAType specModified = type; - while (Objects.nonNull((specModified = growSpec(specModified)))) { + while (Objects.nonNull((specModified = HLAType.growSpec(specModified)))) { if (ALLELE_FREQS.containsKey(specModified)) { return specModified; } @@ -286,7 +289,7 @@ public static HLAType getCWDType(HLAType type) { // Try removing fourth field, or tailing :01's, to the specificity specModified = type; - while (Objects.nonNull((specModified = reduceSpec(specModified)))) { + while (Objects.nonNull((specModified = HLAType.reduceSpec(specModified)))) { if (ALLELE_FREQS.containsKey(specModified)) { return specModified; } @@ -302,7 +305,7 @@ private static Status doGetStatus(HLAType type) { // adding or removing trailing :01's does not change the allele specificity // Try adding :01's to the specificity HLAType specModified = type; - while (Objects.nonNull((specModified = growSpec(specModified)))) { + while (Objects.nonNull((specModified = HLAType.growSpec(specModified)))) { if (ALLELE_FREQS.containsKey(specModified)) { return ALLELE_FREQS.get(specModified); } @@ -310,7 +313,7 @@ private static Status doGetStatus(HLAType type) { // Try removing fourth field, or tailing :01's, to the specificity specModified = type; - while (Objects.nonNull((specModified = reduceSpec(specModified)))) { + while (Objects.nonNull((specModified = HLAType.reduceSpec(specModified)))) { if (ALLELE_FREQS.containsKey(specModified)) { return ALLELE_FREQS.get(specModified); } @@ -318,49 +321,6 @@ private static Status doGetStatus(HLAType type) { return Status.UNKNOWN; } - /** - * @param equivType Input type to reduce - * @return The input {@link HLAType} with its tailing "01" field removed, or null if the allele - * can not be reduced - */ - private static HLAType reduceSpec(HLAType equivType) { - List spec = equivType.spec(); - - if (spec.size() < 2 || (spec.size() < 4 && spec.get(spec.size() - 1) != 1)) { - // We can only remove a trailing "01 "specificity, and only if we have 3- or more fields - return null; - } - - spec = spec.subList(0, spec.size() - 1); - return modifiedSpec(equivType, spec); - } - - /** - * @param equivType Input type to expand - * @return The input {@link HLAType} with an additional "01" field, or null if the allele can not - * be further expanded - */ - private static HLAType growSpec(HLAType equivType) { - List spec = new ArrayList<>(equivType.spec()); - - if (spec.size() >= 4) { - // We can only expand 2- and 3-field specificities - return null; - } - - spec.add(1); - - return modifiedSpec(equivType, spec); - } - - /** Helper method to create an updated HLAType */ - private static HLAType modifiedSpec(HLAType equivType, List spec) { - if (equivType instanceof NullType) { - return new NullType(equivType.locus(), spec); - } - return new HLAType(equivType.locus(), spec); - } - /** * @param alleles Set of alleles * @return A combined weighting of the input allele set, based on their CWD frequencies diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index e9551068..fc41d402 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -8,9 +8,9 @@ import com.sun.javafx.scene.control.skin.resources.ControlResources; import javafx.application.Platform; import javafx.beans.binding.Bindings; -import javafx.beans.property.ReadOnlyObjectProperty; import javafx.collections.FXCollections; import javafx.collections.ObservableList; +import javafx.geometry.Insets; import javafx.geometry.Pos; import javafx.scene.Node; import javafx.scene.control.ButtonBar.ButtonData; @@ -22,9 +22,12 @@ import javafx.scene.control.Label; import javafx.scene.control.ListCell; import javafx.scene.control.ListView; +import javafx.scene.control.RadioButton; +import javafx.scene.control.ToggleGroup; import javafx.scene.layout.GridPane; +import javafx.scene.layout.HBox; import javafx.scene.layout.Priority; -import javafx.scene.layout.Region; +import javafx.scene.layout.VBox; import javafx.util.Callback; import javafx.util.StringConverter; @@ -46,12 +49,16 @@ public class StyleableContingentChoiceDialog extends Dialog { private final GridPane grid; private final Label label; + private final RadioButton opt1Choice; + private final RadioButton opt2Choice; + private final RadioButton manualChoice; private final ComboBox comboBox1; private final ComboBox comboBox2; - private final T defaultChoice; private final CheckBox checkboxFilter1; private final CheckBox checkboxFilter2; private final Predicate filterPredicate; + private final Option opt1; + private final Option opt2; /************************************************************************** @@ -74,15 +81,17 @@ public class StyleableContingentChoiceDialog extends Dialog { * * TODO Encapsulate filterName / filterPredicate so they are optional */ - public StyleableContingentChoiceDialog(Collection choices, Collection invalidChoices, - Multimap secondChoiceMap, Map valueMap, String filterName, - Predicate filter) { - this(null, choices, invalidChoices, secondChoiceMap, valueMap, filterName, filter); - } - public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, Collection invalidChoices, Multimap secondChoiceMap, - Map valueMap, String filterName, Predicate filter) { + Map valueMap, String filterName, + Predicate filter/* + * , BiPredicate textEntryMatcher + */, Option opt1, Option opt2, Node manualChoiceGraphic) { + + // this.textEntryPredicate = textEntryMatcher; + this.opt1 = opt1; + this.opt2 = opt2; + final DialogPane dialogPane = getDialogPane(); // -- grid @@ -94,7 +103,6 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, // -- label label = createContentLabel(dialogPane.getContentText()); - label.setPrefWidth(Region.USE_COMPUTED_SIZE); label.textProperty().bind(dialogPane.contentTextProperty()); setTitle(ControlResources.getString("Dialog.confirm.title")); @@ -102,12 +110,12 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, dialogPane.getStyleClass().add("choice-dialog"); dialogPane.getButtonTypes().addAll(ButtonType.OK, ButtonType.CANCEL); - final double MIN_WIDTH = 150; + final double MIN_WIDTH = 50; comboBox2 = new ComboBox(); comboBox2.setMinWidth(MIN_WIDTH); comboBox2.setMaxWidth(Double.MAX_VALUE); - GridPane.setHgrow(comboBox2, Priority.ALWAYS); + GridPane.setHgrow(comboBox2, Priority.SOMETIMES); GridPane.setFillWidth(comboBox2, true); comboBox2.setMaxHeight(10); comboBox2.setDisable(true); @@ -119,7 +127,7 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, comboBox1.getItems().addAll(choices); } comboBox1.setMaxWidth(Double.MAX_VALUE); - GridPane.setHgrow(comboBox1, Priority.ALWAYS); + GridPane.setHgrow(comboBox1, Priority.SOMETIMES); GridPane.setFillWidth(comboBox1, true); comboBox1.setMaxHeight(10); @@ -131,40 +139,78 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, checkboxFilter1.selectedProperty() .addListener((obs, oldV, newV) -> updateFirstComboChoices(newV, choices)); checkboxFilter2.selectedProperty() - .addListener((obs, oldV, newV) -> updateSecondComboState(secondChoiceMap, newV)); + .addListener((obs, oldV, newV) -> updateSecondComboState(secondChoiceMap, + comboBox1.getSelectionModel().getSelectedItem(), newV)); - comboBox1.valueProperty().addListener((obs, oldV, newV) -> { - try { - Collection c = getSecondChoices(secondChoiceMap, newV, checkboxFilter2.isSelected()); - comboBox2.getSelectionModel().clearSelection(); - comboBox2.getItems().setAll(c); - comboBox2.setDisable(c.isEmpty()); - } catch (Throwable t) { - throw new RuntimeException(t); - } - }); + opt1Choice = new RadioButton(); + opt2Choice = new RadioButton(); + + opt1.graphic.setOnMouseClicked(opt1Choice.getOnMouseClicked()); + opt1.graphic.setOnMouseEntered(opt1Choice.getOnMouseEntered()); + opt1.graphic.setOnMouseExited(opt1Choice.getOnMouseExited()); + opt1.graphic.setOnMousePressed(opt1Choice.getOnMousePressed()); + opt1.graphic.setOnMouseReleased(opt1Choice.getOnMouseReleased()); + + opt2.graphic.setOnMouseClicked(opt2Choice.getOnMouseClicked()); + opt2.graphic.setOnMouseEntered(opt2Choice.getOnMouseEntered()); + opt2.graphic.setOnMouseExited(opt2Choice.getOnMouseExited()); + opt2.graphic.setOnMousePressed(opt2Choice.getOnMousePressed()); + opt2.graphic.setOnMouseReleased(opt2Choice.getOnMouseReleased()); + + manualChoice = new RadioButton(); + manualChoice.setGraphic(manualChoiceGraphic); - this.defaultChoice = comboBox1.getItems().contains(defaultChoice) ? defaultChoice : null; + ToggleGroup group = new ToggleGroup(); + opt1Choice.setToggleGroup(group); + opt2Choice.setToggleGroup(group); + manualChoice.setToggleGroup(group); if (defaultChoice != null) { comboBox1.getSelectionModel().select(defaultChoice); } + // these are basic bindings + checkboxFilter1.disableProperty().bind(manualChoice.selectedProperty().not()); + checkboxFilter2.disableProperty().bind(manualChoice.selectedProperty().not()); + comboBox1.disableProperty().bind(manualChoice.selectedProperty().not()); + + // this is a more complex binding: + // we want to disable the combobox if no options are available + comboBox2.disableProperty().bind(Bindings.createBooleanBinding(() -> { + boolean enable = manualChoice.selectedProperty().get() + && !comboBox1.getSelectionModel().isEmpty() && !comboBox2.getItems().isEmpty(); + return !enable; + }, manualChoice.selectedProperty(), comboBox1.selectionModelProperty(), + comboBox1.getSelectionModel().selectedItemProperty(), comboBox2.itemsProperty())); + + // update the second combobox items when the first combobox selection changes + comboBox1.getSelectionModel().selectedItemProperty().addListener((obs, oldV, newV) -> { + // comboBox1.valueProperty().addListener((obs, oldV, newV) -> { + try { + updateSecondComboState(secondChoiceMap, newV, checkboxFilter2.isSelected()); + } catch (Throwable t) { + throw new RuntimeException(t); + } + }); + Node okButton = dialogPane.lookupButton(ButtonType.OK); okButton.disableProperty().bind(Bindings.createBooleanBinding(() -> { - return comboBox2.disableProperty().get() + return (comboBox2.disableProperty().get() || invalidChoices.contains(comboBox1.getSelectionModel().getSelectedItem()) || invalidChoices.contains(comboBox2.getSelectionModel().getSelectedItem()) - || comboBox2.getSelectionModel().isEmpty(); + || comboBox2.getSelectionModel().isEmpty()) + && !(opt1Choice.selectedProperty().get() || opt2Choice.selectedProperty().get()); // for this .isEmpty() call to work, // the binding must include the // selectedItemProperty as a dependency - }, comboBox2.disableProperty(), comboBox2.getSelectionModel().selectedItemProperty())); + }, comboBox2.disableProperty(), comboBox2.getSelectionModel().selectedItemProperty(), + opt1Choice.selectedProperty(), opt2Choice.selectedProperty())); - dialogPane.contentTextProperty().addListener(o -> updateGrid(comboBox1)); + dialogPane.contentTextProperty() + .addListener(o -> updateGrid(this.getDialogPane().lookupButton(ButtonType.CANCEL))); - updateGrid(comboBox1); + updateGrid(this.getDialogPane().lookupButton(ButtonType.CANCEL)); setResultConverter((dialogButton) -> { ButtonData data = dialogButton == null ? null : dialogButton.getButtonData(); @@ -174,41 +220,43 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, } - private void updateFirstComboChoices(boolean filterActive, Collection choices) { + private ObservableList getFirstComboChoices(boolean filterActive, Collection choices) { ObservableList filteredChoices = choices.stream().filter(item -> !filterActive || filterPredicate.test(item)) .collect(Collectors.toCollection(FXCollections::observableArrayList)); - comboBox1.setItems(filteredChoices); - if (!filteredChoices.contains(comboBox1.getSelectionModel().getSelectedItem())) { - comboBox1.getSelectionModel().clearSelection(); - } + return filteredChoices; } - - private void updateSecondComboState(Multimap secondChoiceMap, boolean filterActive) { - T selectedFirstItem = comboBox1.getSelectionModel().getSelectedItem(); - ObservableList secondChoices = - FXCollections.observableArrayList(secondChoiceMap.get(selectedFirstItem)); + private ObservableList getSecondComboChoices(Multimap secondChoiceMap, + T selectedFirstItem, boolean filterActive) { + ObservableList secondChoices; + secondChoices = FXCollections.observableArrayList(secondChoiceMap.get(selectedFirstItem)); if (filterActive) { secondChoices = secondChoices.stream().filter(filterPredicate) .collect(Collectors.toCollection(FXCollections::observableArrayList)); } + return secondChoices; + } + + private void updateFirstComboChoices(boolean filterActive, Collection choices) { + ObservableList filteredChoices = getFirstComboChoices(filterActive, choices); + comboBox1.setItems(filteredChoices); + if (!filteredChoices.contains(comboBox1.getSelectionModel().getSelectedItem())) { + comboBox1.getSelectionModel().clearSelection(); + } + } + + private void updateSecondComboState(Multimap secondChoiceMap, T selectedFirstItem, + boolean filterActive) { + ObservableList secondChoices; + secondChoices = getSecondComboChoices(secondChoiceMap, selectedFirstItem, filterActive); comboBox2.setItems(secondChoices); - comboBox2.setDisable(secondChoices.isEmpty()); if (!secondChoices.contains(comboBox2.getSelectionModel().getSelectedItem())) { comboBox2.getSelectionModel().clearSelection(); } } - private Collection getSecondChoices(Multimap secondChoiceMap, T newV, boolean filter) { - Collection c = secondChoiceMap.get(newV); - - if (filter) { - c = c.stream().filter(filterPredicate).collect(Collectors.toList()); - } - return c; - } /************************************************************************** * @@ -220,11 +268,25 @@ private Collection getSecondChoices(Multimap secondChoiceMap, T newV, b * Returns the currently selected item in the dialog. */ public final T getSelectedItem() { - return comboBox1.getSelectionModel().getSelectedItem(); + if (manualChoice.isSelected()) { + return comboBox1.getSelectionModel().getSelectedItem(); + } else if (opt1Choice.isSelected()) { + return opt1.opt1; + } else if (opt2Choice.isSelected()) { + return opt2.opt1; + } + return null; } public final T getSelectedSecondItem() { - return comboBox2.getSelectionModel().getSelectedItem(); + if (manualChoice.isSelected()) { + return comboBox2.getSelectionModel().getSelectedItem(); + } else if (opt1Choice.isSelected()) { + return opt1.opt2; + } else if (opt2Choice.isSelected()) { + return opt2.opt2; + } + return null; } public void setCombo1CellFactory(Callback, ListCell> value) { @@ -251,37 +313,6 @@ public void setConverter2(StringConverter c) { comboBox2.setConverter(c); } - /** - * Returns the property representing the currently selected item in the dialog. - */ - public final ReadOnlyObjectProperty selectedItemProperty() { - return comboBox1.getSelectionModel().selectedItemProperty(); - } - - /** - * Sets the currently selected item in the dialog. - * - * @param item The item to select in the dialog. - */ - public final void setSelectedItem(T item) { - comboBox1.getSelectionModel().select(item); - } - - /** - * Returns the list of all items that will be displayed to users. This list can be modified by the - * developer to add, remove, or reorder the items to present to the user. - */ - public final ObservableList getItems() { - return comboBox1.getItems(); - } - - /** - * Returns the default choice that was specified in the constructor. - */ - public final T getDefaultChoice() { - return defaultChoice; - } - /************************************************************************** * * Private Implementation @@ -302,13 +333,46 @@ private void updateGrid(Node focusReq) { grid.getChildren().clear(); grid.add(label, 0, 0); - grid.add(checkboxFilter1, 0, 1); - grid.add(comboBox1, 0, 2); - grid.add(checkboxFilter2, 0, 3); - grid.add(comboBox2, 0, 4); + HBox hBox1 = new HBox(); + hBox1.getChildren().add(opt1Choice); + hBox1.getChildren().add(opt1.graphic); + HBox.setHgrow(opt1.graphic, Priority.ALWAYS); + + + grid.add(hBox1, 0, 1); + HBox hBox2 = new HBox(); + hBox2.getChildren().add(opt2Choice); + hBox2.getChildren().add(opt2.graphic); + HBox.setHgrow(opt2.graphic, Priority.ALWAYS); + grid.add(hBox2, 0, 2); + grid.add(manualChoice, 0, 3); + VBox subGrid = new VBox(); + subGrid.setSpacing(10); + subGrid.setPadding(new Insets(0, 0, 0, 20)); + subGrid.getChildren().add(checkboxFilter1); + subGrid.getChildren().add(comboBox1); + subGrid.getChildren().add(checkboxFilter2); + subGrid.getChildren().add(comboBox2); + grid.add(subGrid, 0, 4); + + grid.setPadding(new Insets(10, 0, 10, 25)); + getDialogPane().setContent(grid); Platform.runLater(() -> focusReq.requestFocus()); } + public static class Option { + final Node graphic; + final T opt1; + final T opt2; + + public Option(Node graphic, T opt1, T opt2) { + this.graphic = graphic; + this.opt1 = opt1; + this.opt2 = opt2; + } + + } + } diff --git a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java index 39e00e59..f34fa52a 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java +++ b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java @@ -167,6 +167,8 @@ private void selectDonorFile(ActionEvent event, DonorFileParser donorParser, alertInvalid(donorParser, selectedFile, validationResult); } + + // check for corrections if (builder.hasCorrectionsIfSoStartLoading()) { diff --git a/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java b/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java index 5aab3cca..e0786a85 100644 --- a/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java +++ b/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java @@ -22,11 +22,9 @@ package org.pankratzlab.unet.model; import java.util.Objects; - import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.hapstats.Haplotype; import org.pankratzlab.unet.hapstats.RaceGroup; - import javafx.beans.property.ReadOnlyObjectProperty; import javafx.beans.property.ReadOnlyObjectWrapper; @@ -63,9 +61,18 @@ public DRDQHaplotypeRow(RaceGroup ethnicity, Haplotype haplotype) { break; } } - if (Objects.isNull(dqb1) || Objects.isNull(drb1) || Objects.isNull(drb345)) { + // TODO split into separate throws indicating which is missing + if (Objects.isNull(dqb1)) { + throw new IllegalArgumentException( + "Invalid DRB345-DRB1-DQB1 haplotype, missing DQB1: " + haplotype.toShortString()); + } + if (Objects.isNull(drb1)) { + throw new IllegalArgumentException( + "Invalid DRB345-DRB1-DQB1 haplotype, missing DRB1: " + haplotype.toShortString()); + } + if (Objects.isNull(drb345)) { throw new IllegalArgumentException( - "Invalid DRB345-DRB1-DQB1 haplotype: " + haplotype.toShortString()); + "Invalid DRB345-DRB1-DQB1 haplotype, missing DRB345: " + haplotype.toShortString()); } alleleDRB1 = getAlleleWrapper(drb1); diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 7da47758..400719ee 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -61,6 +61,7 @@ import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog; +import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog.Option; import org.pankratzlab.unet.parser.util.BwSerotypes; import org.pankratzlab.unet.parser.util.BwSerotypes.BwGroup; import org.pankratzlab.unet.parser.util.DRAssociations; @@ -76,6 +77,7 @@ import com.google.common.collect.ImmutableMultimap; import com.google.common.collect.ImmutableSet; import com.google.common.collect.ImmutableSortedSet; +import com.google.common.collect.LinkedListMultimap; import com.google.common.collect.ListMultimap; import com.google.common.collect.Lists; import com.google.common.collect.Multimap; @@ -83,8 +85,13 @@ import com.google.common.collect.MultimapBuilder.SortedSetMultimapBuilder; import com.google.common.collect.Sets; import com.google.common.collect.Table; +import javafx.geometry.Pos; +import javafx.scene.control.Label; import javafx.scene.control.ListCell; import javafx.scene.control.Tooltip; +import javafx.scene.layout.HBox; +import javafx.scene.layout.Priority; +import javafx.scene.layout.Region; import javafx.scene.text.Text; import javafx.scene.text.TextFlow; import javafx.util.Duration; @@ -572,7 +579,7 @@ public String toString(Supplier object) { @Override public Supplier fromString(String string) { - return null; + return choices.getPresentation(string); } } @@ -973,8 +980,12 @@ private ValidationResult ensureValidity() { BackgroundDataProcessor choiceSupplier; + public boolean hasCorrections() { + return !nonCWDLoci.isEmpty(); + } + public boolean hasCorrectionsIfSoStartLoading() { - if (!nonCWDLoci.isEmpty()) { + if (hasCorrections()) { // start loading data in the background choiceSupplier = new BackgroundDataProcessor<>(nonCWDLoci, (locus) -> PresentableAlleleChoices.create(locus, getAllelePairs(locus)), (t) -> { @@ -988,87 +999,222 @@ public boolean hasCorrectionsIfSoStartLoading() { public ValidationResult processCorrections() { + boolean cancelled = false; + for (HLALocus locus : nonCWDLoci) { - AllelePairings allelePairs = possibleAllelePairings.get(locus); - AllelePairings donorPairs = donorAllelePairings.get(locus); - - Set locusSet; - Set locusSetNonCWD; - Set typesSet; - Set typesSetNonCWD; - - // TODO replace this switch-statement with OOP design somehow... - switch (locus) { - case A: - locusSet = aLocusCWD; - locusSetNonCWD = aLocusFirst; - typesSet = aLocusCWDTypes; - typesSetNonCWD = aLocusFirstTypes; - break; - case B: - locusSet = bLocusCWD; - locusSetNonCWD = bLocusFirst; - typesSet = bLocusCWDTypes; - typesSetNonCWD = bLocusFirstTypes; - break; - case C: - locusSet = cLocusCWD; - locusSetNonCWD = cLocusFirst; - typesSet = cLocusCWDTypes; - typesSetNonCWD = cLocusFirstTypes; - break; - case DPA1: - locusSet = dpaLocus; - locusSetNonCWD = dpaLocusNonCWD; - typesSet = dpaLocusTypes; - typesSetNonCWD = dpaLocusTypesNonCWD; - break; - case DQA1: - locusSet = dqaLocus; - locusSetNonCWD = dqaLocusNonCWD; - typesSet = dqaLocusTypes; - typesSetNonCWD = dqaLocusTypesNonCWD; - break; - case DPB1: - locusSet = null; - locusSetNonCWD = dpbLocusNonCWD.stream().map(HLAType::equivSafe) - .collect(ImmutableSet.toImmutableSet()); - typesSet = dpbLocusTypes; - typesSetNonCWD = dpbLocusTypesNonCWD; - case DQB1: - locusSet = dqbLocus; - locusSetNonCWD = dqbLocusNonCWD; - typesSet = dqbLocusTypes; - typesSetNonCWD = dqbLocusTypesNonCWD; - default: - allelePairs = null; - donorPairs = null; - locusSet = null; - locusSetNonCWD = null; - typesSet = null; - typesSetNonCWD = null; - break; + Pair, Set> remapPair = null; + + try { + remapPair = processRemap(locus, this); + } catch (CancellationException e) { + cancelled = true; } - if (allelePairs == null || donorPairs == null) { - // TODO - continue; + + if (remapPair != null) { + remapping.put(locus, remapPair); } + } + + if (cancelled) { + return new ValidationResult(false, Optional.empty()); + } + + return new ValidationResult(true, Optional.empty()); + } + + private class CancellationException extends RuntimeException { + + private static final long serialVersionUID = 1L; + + // used to indicate user-cancellation of locus remapping + + } + + interface RemapProcessor { + + public Pair, Set> processRemapping(HLALocus locus, + ValidationModelBuilder builder) throws CancellationException; + + } + + public Set getCWDSeroTypesForLocus(HLALocus locus) { + + switch (locus) { + case A: + return aLocusCWD; + case B: + return bLocusCWD; + case C: + return cLocusCWD; + case DPA1: + return dpaLocus; + case DQA1: + return dqaLocus; + case DPB1: + return null; + case DQB1: + return dqbLocus; + default: + return null; + } + + } + + public Set getAllSeroTypesForLocus(HLALocus locus) { + + switch (locus) { + case A: + return aLocusFirst; + case B: + return bLocusFirst; + case C: + return cLocusFirst; + case DPA1: + return dpaLocusNonCWD; + case DQA1: + return dqaLocusNonCWD; + case DPB1: + return dpbLocusNonCWD.stream().map(HLAType::equivSafe) + .collect(ImmutableSet.toImmutableSet()); + case DQB1: + return dqbLocusNonCWD; + default: + return null; + } + + } + + public Set getCWDTypesForLocus(HLALocus locus) { - Iterator iter = locusSetNonCWD == null ? null : locusSetNonCWD.iterator(); - String header = "Assigned allele pair (" + typesSetNonCWD.stream().map(ht -> { - return (iter == null ? "" : (iter.next()) + " / ") + ht.specString() + " - " - + CommonWellDocumented.getEquivStatus(ht); - }).collect(Collectors.joining(", ")) + ") for HLA-" + locus.name() - + " locus is not Common / Well-Documented."; + switch (locus) { + case A: + return aLocusCWDTypes; + case B: + return bLocusCWDTypes; + case C: + return cLocusCWDTypes; + case DPA1: + return dpaLocusTypes; + case DQA1: + return dqaLocusTypes; + case DPB1: + return dpbLocusTypes; + case DQB1: + return dqbLocusTypes; + default: + return null; + } + + } + + public Set getAllTypesForLocus(HLALocus locus) { + switch (locus) { + case A: + return aLocusFirstTypes; + case B: + return bLocusFirstTypes; + case C: + return cLocusFirstTypes; + case DPA1: + return dpaLocusTypesNonCWD; + case DQA1: + return dqaLocusTypesNonCWD; + case DPB1: + return dpbLocusTypesNonCWD; + case DQB1: + return dqbLocusTypesNonCWD; + default: + return null; + } + } + + private AllelePairings getPossibleAllelePairsForLocus(HLALocus locus) { + return possibleAllelePairings.get(locus); + } - String text = - "Please select desired allele pair for this locus. Selecting the first allele will populate valid pairings for the second allele."; + private AllelePairings getDonorAllelePairsForLocus(HLALocus locus) { + return donorAllelePairings.get(locus); + } + + private static class GUIRemapProcessor implements RemapProcessor { + + private Pair, Set> processRemap(HLALocus locus, + ValidationModelBuilder builder) { + AllelePairings allelePairs = builder.getPossibleAllelePairsForLocus(locus); + AllelePairings donorPairs = builder.getDonorAllelePairsForLocus(locus); + + Set locusSet = builder.getCWDSeroTypesForLocus(locus); + Set locusSetNonCWD = builder.getAllSeroTypesForLocus(locus); + Set typesSet = builder.getCWDTypesForLocus(locus); + Set typesSetNonCWD = builder.getAllTypesForLocus(locus); + + if (allelePairs == null || donorPairs == null) { + // TODO + return null; + } // FIXME TODO this needs to be done on a Task thread to show a progress spinner if it blocks // while loading. However, the choice dialogs need to be created on the JavaFX thread. // But also, this method overall needs to return a single validation result object ... PresentableAlleleChoices choices = choiceSupplier.get(locus); + Iterator typeIter; + Iterator seroIter; + + typeIter = typesSet.iterator(); + HLAType hlaType1_CIWD = typeIter.next(); + HLAType hlaType2_CIWD = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; + + // seroIter = locusSet.iterator(); + // SeroType seroType1_CIWD = seroIter.next(); + // SeroType seroType2_CIWD = seroIter.hasNext() ? seroIter.next() : seroType1_CIWD; + + typeIter = typesSetNonCWD.iterator(); + HLAType hlaType1_First = typeIter.next(); + HLAType hlaType2_First = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; + + seroIter = locusSetNonCWD.iterator(); + SeroType seroType1_First = seroIter.next(); + SeroType seroType2_First = seroIter.hasNext() ? seroIter.next() : seroType1_First; + + // TODO encapsulate Allele selection JavaFX components in a different class in the JFX + // packages + // ValidationModelBuilder shouldn't know about JavaFX UI components + + HBox assignedPane = new HBox(10); + assignedPane.setMaxWidth(Double.MAX_VALUE); + assignedPane.setAlignment(Pos.CENTER_LEFT); + Label assignedHeader = new Label("Assigned allele pair: "); + TextFlow assignedTextFlow = new TextFlow(); + addTextNodes(assignedTextFlow, hlaType1_First.toString(), true); + assignedTextFlow.getChildren().add(new Text(" | ")); + addTextNodes(assignedTextFlow, hlaType2_First.toString(), true); + Label assignedHeaderLbl = new Label("", assignedTextFlow); + assignedHeaderLbl.setMaxWidth(Double.MAX_VALUE); + assignedHeaderLbl.setMaxHeight(Double.MAX_VALUE); + assignedPane.getChildren().add(assignedHeader); + assignedPane.getChildren().add(getSpacer()); + assignedPane.getChildren().add(assignedHeaderLbl); + + HBox ciwdPane = new HBox(10); + ciwdPane.setMaxWidth(Double.MAX_VALUE); + ciwdPane.setAlignment(Pos.CENTER_LEFT); + Label ciwdHeader = new Label("Common / Well-Documented allele pair: "); + TextFlow ciwdTextFlow = new TextFlow(); + addTextNodes(ciwdTextFlow, hlaType1_CIWD.toString(), true); + ciwdTextFlow.getChildren().add(new Text(" | ")); + addTextNodes(ciwdTextFlow, hlaType2_CIWD.toString(), true); + Label ciwdHeaderLbl = new Label("", ciwdTextFlow); + ciwdHeaderLbl.setMaxWidth(Double.MAX_VALUE); + ciwdHeaderLbl.setMaxHeight(Double.MAX_VALUE); + ciwdPane.getChildren().add(ciwdHeader); + ciwdPane.getChildren().add(getSpacer()); + ciwdPane.getChildren().add(ciwdHeaderLbl); + + String text = "Or manually select allele pair for this locus"; + String text1 = + "(selecting the first allele will populate valid pairings for the second allele)"; + final List> allChoices = choices.getAllChoices(); Function, String> tooltipProvider = (tf) -> { @@ -1080,12 +1226,26 @@ public ValidationResult processCorrections() { return isAnyPartCWD(choices.getData(tf)); }; + StyleableContingentChoiceDialog.Option> opt1 = + new Option<>(assignedPane, choices.getChoiceForAllele(hlaType1_First.toString()), + choices.getChoiceForAllele(hlaType2_First.toString())); + + StyleableContingentChoiceDialog.Option> opt2 = + new Option<>(ciwdPane, choices.getChoiceForAllele(hlaType1_CIWD.toString()), + choices.getChoiceForAllele(hlaType2_CIWD.toString())); + + Label manualChoice = new Label(text + System.lineSeparator() + text1); + StyleableContingentChoiceDialog> cd = - new StyleableContingentChoiceDialog<>(allChoices, Lists.newArrayList(), - choices.getAllSecondChoices(), choices.dataMap, filterName, filter); + new StyleableContingentChoiceDialog<>(null, allChoices, Lists.newArrayList(), + choices.getAllSecondChoices(), choices.dataMap, filterName, + filter/* , textEntryMatcher */, opt1, opt2, manualChoice); cd.setTitle("Select HLA-" + locus.name() + " Alleles"); - cd.setHeaderText(header); - cd.setContentText(text); + + cd.setHeaderText("Assigned allele pair for HLA-" + locus.name() + + " locus is not Common / Well-Documented."); + cd.setContentText("Please select desired allele pair for this locus:"); + cd.setCombo1CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); cd.setCombo1ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); cd.setCombo2CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); @@ -1096,7 +1256,7 @@ public ValidationResult processCorrections() { Optional> result = cd.showAndWait(); if (!result.isPresent()) { - return new ValidationResult(false, Optional.empty()); + throw new CancellationException(); } Supplier selAllele1 = result.get(); @@ -1110,14 +1270,6 @@ public ValidationResult processCorrections() { SeroType seroType1 = hlaType1.equivSafe(); SeroType seroType2 = hlaType2.equivSafe(); - final Iterator typeIter = typesSet.iterator(); - HLAType hlaType1Old = typeIter.next(); - HLAType hlaType2Old = typeIter.hasNext() ? typeIter.next() : hlaType1Old; - - final Iterator seroIter = locusSet.iterator(); - SeroType seroType1Old = seroIter.next(); - SeroType seroType2Old = seroIter.hasNext() ? seroIter.next() : seroType1Old; - locusSet.clear(); locusSet.add(seroType1); locusSet.add(seroType2); @@ -1126,23 +1278,30 @@ public ValidationResult processCorrections() { typesSet.add(hlaType2); boolean a1Match = - hlaType1.compareTo(hlaType1Old) == 0 || hlaType1.compareTo(hlaType2Old) == 0; + hlaType1.compareTo(hlaType1_First) == 0 || hlaType1.compareTo(hlaType2_First) == 0; boolean a2Match = - hlaType2.compareTo(hlaType1Old) == 0 || hlaType2.compareTo(hlaType2Old) == 0; + hlaType2.compareTo(hlaType1_First) == 0 || hlaType2.compareTo(hlaType2_First) == 0; if (!a1Match || !a2Match) { - ImmutableSortedSet prevSet = ImmutableSortedSet - .of(new TypePair(hlaType1Old, seroType1Old), new TypePair(hlaType2Old, seroType2Old)); + ImmutableSortedSet prevSet = + ImmutableSortedSet.of(new TypePair(hlaType1_First, seroType1_First), + new TypePair(hlaType2_First, seroType2_First)); ImmutableSortedSet newSet = ImmutableSortedSet .of(new TypePair(hlaType1, seroType1), new TypePair(hlaType2, seroType2)); - remapping.put(locus, Pair.of(prevSet, newSet)); + return Pair.of(prevSet, newSet); } + + return null; } + } - return new ValidationResult(true, Optional.empty()); + private Region getSpacer() { + Region spacer = new Region(); + HBox.setHgrow(spacer, Priority.ALWAYS); + return spacer; } private AllelePairings getAllelePairs(HLALocus locus) { @@ -1198,9 +1357,10 @@ public static PresentableAlleleChoices create(HLALocus locus, AllelePairings all List alleleKeys = new ArrayList<>(allelePairings.map.keySet()); sortAlleleStrings(alleleKeys); - List choiceList = condenseIntoGroups(allelePairings, alleleKeys, true); + LinkedListMultimap choiceList = + condenseIntoGroups(allelePairings, alleleKeys, true); - for (String allele : choiceList) { + for (String allele : choiceList.keySet()) { Supplier supp = () -> getText(allele); userChoices.add(supp); @@ -1218,9 +1378,10 @@ public static PresentableAlleleChoices create(HLALocus locus, AllelePairings all List pairings = new ArrayList<>(allelePairings.getValidPairings(pairingAllele)); sortAlleleStrings(pairings); - List secondChoicePairings = condenseIntoGroups(allelePairings, pairings, false); + LinkedListMultimap secondChoicePairings = + condenseIntoGroups(allelePairings, pairings, false); - for (String pairing : secondChoicePairings) { + for (String pairing : secondChoicePairings.keySet()) { Supplier presentationView = presentationToDataMap.inverse().get(pairing); if (presentationView == null) { presentationView = () -> getText(pairing); @@ -1230,12 +1391,17 @@ public static PresentableAlleleChoices create(HLALocus locus, AllelePairings all } } + Map alleleToGroupMap = new HashMap<>(); + choiceList.entries().stream().forEach(e -> { + alleleToGroupMap.put(e.getValue(), e.getKey()); + }); + return new PresentableAlleleChoices(userChoices, secondChoices, presentationToDataMap, - allelePairings); + allelePairings, alleleToGroupMap); } - private static List condenseIntoGroups(AllelePairings allelePairings, - List alleleKeys, boolean checkPairings) { + private static LinkedListMultimap condenseIntoGroups( + AllelePairings allelePairings, List alleleKeys, boolean checkPairings) { List> subsets = new ArrayList<>(); List subset = new ArrayList<>(); @@ -1294,7 +1460,7 @@ private static List condenseIntoGroups(AllelePairings allelePairings, subsets.add(subset); } - List choiceList = new ArrayList<>(); + LinkedListMultimap groupToAllelesMap = LinkedListMultimap.create(); // now we need to process the subset lists // single element subsets can be added directly @@ -1305,7 +1471,7 @@ private static List condenseIntoGroups(AllelePairings allelePairings, for (List sub : subsets) { if (sub.size() == 1) { - choiceList.add(sub.get(0)); + groupToAllelesMap.put(sub.get(0), sub.get(0)); continue; } @@ -1349,14 +1515,17 @@ private static List condenseIntoGroups(AllelePairings allelePairings, for (List subS : subSubsets) { if (subS.size() == 1) { - choiceList.add(subS.get(0)); + groupToAllelesMap.put(subS.get(0), subS.get(0)); } else { - choiceList.add(subS.get(0) + "-" + subS.get(subS.size() - 1)); + String groupName = subS.get(0) + "-" + subS.get(subS.size() - 1); + for (String s : subS) { + groupToAllelesMap.put(groupName, s); + } } } - } - return choiceList; + + return groupToAllelesMap; } private static void sortAlleleStrings(List alleleKeys) { @@ -1422,11 +1591,19 @@ private static void sortAlleleStrings(List alleleKeys) { private final AllelePairings allelePairs; + Map alleleToGroupKeyMap; + + public Supplier getChoiceForAllele(String allele) { + return getPresentation(alleleToGroupKeyMap.get(allele)); + } + private PresentableAlleleChoices(List> choices, Multimap, Supplier> secondChoices, - BiMap, String> presentationToDataMap, AllelePairings allelePairs) { + BiMap, String> presentationToDataMap, AllelePairings allelePairs, + Map alleleToGroupMap) { super(choices, secondChoices, presentationToDataMap); this.allelePairs = allelePairs; + this.alleleToGroupKeyMap = alleleToGroupMap; } @Override @@ -1438,19 +1615,17 @@ public List> getMatchingChoices(String userInput) { } private static TextFlow getText(String allele) { - List textNodes = new ArrayList<>(); + TextFlow flow = new TextFlow(); if (allele.contains("-")) { String[] a = allele.split("-"); - addTextNodes(textNodes, a[0], false); - textNodes.add(new Text(" - ")); - addTextNodes(textNodes, a[1], true); + addTextNodes(flow, a[0], false); + flow.getChildren().add(new Text(" - ")); + addTextNodes(flow, a[1], true); } else { - addTextNodes(textNodes, allele, true); + addTextNodes(flow, allele, true); } - Text[] nodes = textNodes.toArray(new Text[textNodes.size()]); - TextFlow tf = new TextFlow(nodes); - return tf; + return flow; } private boolean isAnyPartCWD(String allele) { @@ -1460,12 +1635,12 @@ private boolean isAnyPartCWD(String allele) { return status1 != Status.UNKNOWN; } - private static void addTextNodes(List textNodes, final String allele, boolean addSero) { + private static void addTextNodes(TextFlow flow, final String allele, boolean addSero) { HLAType alleleType = HLAType.valueOf(allele); HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); Status status1 = CommonWellDocumented.getStatus(alleleType); - textNodes.add(new Text(alleleType.locus().name() + "*")); + flow.getChildren().add(new Text(alleleType.locus().name() + "*")); String specString = alleleType.specString(); boolean match = allele.matches(NOT_EXPRESSED) || allele.matches(NOT_ON_CELL_SURFACE); @@ -1475,25 +1650,25 @@ private static void addTextNodes(List textNodes, final String allele, bool if (cwdType1.specString().length() < specString.length()) { Text t1 = new Text(cwdType1.specString()); t1.setStyle("-fx-font-weight:bold;"); - textNodes.add(t1); - textNodes.add(new Text(specString.substring(cwdType1.specString().length()))); + flow.getChildren().add(t1); + flow.getChildren().add(new Text(specString.substring(cwdType1.specString().length()))); } else { Text t1 = new Text(specString); t1.setStyle("-fx-font-weight:bold;"); - textNodes.add(t1); + flow.getChildren().add(t1); } if (match) { - textNodes.add(new Text("" + allele.charAt(allele.length() - 1))); + flow.getChildren().add(new Text("" + allele.charAt(allele.length() - 1))); } } else { - textNodes + flow.getChildren() .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); } if (addSero) { - textNodes.add( + flow.getChildren().add( new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); } } @@ -1577,13 +1752,6 @@ private Set makeIfNull(Set locusSet) { return locusSet; } - /** - * Helper method to create {@link HLAType}s and add them to a locus's set in a consistent manner - */ - private void addToLocus(Set locusSet, HLALocus locus, String typeString) { - locusSet.add(new HLAType(locus, typeString)); - } - /** * Helper method to create {@link HLAType}s and add them to a locus's set in a consistent manner */ @@ -1631,151 +1799,6 @@ public Collection getMatchingAlleles(String pattern) { } - public static class AlleleGroupPairings { - - private List> groupings1 = new ArrayList<>(); - private List> groupings2 = new ArrayList<>(); - private Map>> alleleToGroupsMap = new HashMap<>(); - private Map> alleleToGroupIndexMap = new HashMap<>(); - private Multimap map = HashMultimap.create(); - - public List> getAllGroups() { - List> list = new ArrayList<>(groupings1); - list.addAll(groupings2); - return list; - } - - /** - * AlleleList groupings/entries - * - * Alleles in alleleList1 entries will only have one set, but alleles in alleleList2 entries - * will have multiple sets - */ - public void addAllele1Grouping(Collection alleles) { - processAlleles(alleles, groupings1); - } - - /** - * AlleleList groupings/entries - * - * Alleles in alleleList1 entries will only have one set, but alleles in alleleList2 entries - * will have multiple sets - */ - public void addAllele2Grouping(Collection alleles) { - processAlleles(alleles, groupings2); - } - - private void processAlleles(Collection alleles, List> groupings) { - // create group - Set group = Sets.newTreeSet(alleles); - - // if already present, return - if (groupings.contains(group)) - return; - - // add to list of groups - groupings.add(group); - - // compute index of group in list - int ind = groupings.size() - 1; - - for (String allele : alleles) { - // connect each allele to the group it's in - Set> s = alleleToGroupsMap.get(allele); - if (s == null) { - alleleToGroupsMap.put(allele, s = new HashSet<>()); - } - s.add(group); - - // retain the index of the group also for quick access (may not end up needing this) - Set i = alleleToGroupIndexMap.get(allele); - if (i == null) { - alleleToGroupIndexMap.put(allele, i = new HashSet<>()); - } - i.add(ind); - } - } - - /** - * For each allele(a1) in AlleleList1: For each allele(a2) in AlleleList2: addPairing(a1, a2) - * - * @param a1 - * @param a2 - */ - public void addPairing(String a1, String a2) { - map.put(a1, a2); - map.put(a2, a1); - } - - public boolean isValidGroup(Collection alleles) { - if (alleles == null || alleles.isEmpty()) - return false; - - for (Set group : groupings1) { - if (group.containsAll(alleles)) - return true; - } - for (Set group : groupings2) { - if (group.containsAll(alleles)) - return true; - } - return false; - } - - public List> getGroups(Collection alleles) { - List> found = new ArrayList<>(); - for (Set group : groupings1) { - if (group.containsAll(alleles)) - found.add(group); - } - for (Set group : groupings2) { - if (group.containsAll(alleles)) - found.add(group); - } - return found; - } - - public Collection getValidPairings(String allele) { - return map.get(allele); - } - - public List> getValidPairGroups(Set alleles) { - if (!isValidGroup(alleles)) - return new ArrayList<>(); - - Iterator iter = alleles.iterator(); - Set allPairings = new HashSet<>(getValidPairings(iter.next())); - while (iter.hasNext() && !allPairings.isEmpty()) { - Set currPairs = new HashSet<>(allPairings); - Set nextPairs = new HashSet<>(getValidPairings(iter.next())); - allPairings.clear(); - Sets.intersection(currPairs, nextPairs).copyInto(allPairings); - } - - if (allPairings.isEmpty()) - return new ArrayList<>(); - - List> validGroupPairings = new ArrayList<>(); - for (Set g : groupings1) { - if (allPairings.containsAll(g)) - validGroupPairings.add(g); - } - for (Set g : groupings2) { - if (allPairings.containsAll(g)) - validGroupPairings.add(g); - } - - return validGroupPairings; - } - - public Collection getMatchingAlleles(String pattern) { - final RabinKarp rabinKarp = new RabinKarp(pattern); - return map.keySet().stream().filter(s -> rabinKarp.search(s) < s.length()) - .collect(Collectors.toSet()); - } - - } - public static class TypePair implements Comparable { private final HLAType hlaType; private final SeroType seroType; diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index 0c16c897..0881df7a 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -48,6 +48,37 @@ public final class SerotypeEquivalence { static { careDxEquivalencies = buildLookupFromCareDxXMLFile(); manualEquivalencies = buildManualOverrideLookup(); + + // List test = Lists.newArrayList("B*15:15", "B*15:15:01", "B*15:15:01:01"); + // Set hset = new HashSet<>(); + // for (String t : test) { + // HLAType h = HLAType.valueOf(t); + // hset.add(h); + // System.out.println(h.toString() + "\t" + h.equivSafe()); + // } + // + // test = + // Lists.newArrayList("B*15:08", "B*15:08:01", "B*15:08:01:01", "B*15:08:01:02", "B*15:08:02"); + // hset = new HashSet<>(); + // for (String t : test) { + // HLAType h = HLAType.valueOf(t); + // hset.add(h); + // System.out.println(h.toString() + "\t" + h.equivSafe()); + // } + + for (HLAType h : manualEquivalencies.keySet()) { + SeroType newS = careDxEquivalencies.get(h); + SeroType oldS = manualEquivalencies.get(h); + SeroType autoS = h.equivSafe(); + SeroType autoLS = h.lowResEquiv(); + if (newS == null) { + System.out.println(h + "\t" + oldS + "\t" + autoLS + "\t" + autoS); + } else if (oldS.compareTo(newS) != 0) { + System.out.println( + "----------- " + h + ": was " + oldS + " || now is " + newS + " (auto: " + autoS + ")"); + } + } + } private static ImmutableMap buildLookupFromCareDxXMLFile() { @@ -147,6 +178,9 @@ private static ImmutableMap buildManualOverrideLookup() { // put method for creating the reference table used in the get method. private static void put(Builder builder, String serotypeSpec, HLALocus locus, String... hlaSpecs) { + if (serotypeSpec.contains("(")) { + System.out.println(); + } SeroType s = new SeroType(locus.sero(), serotypeSpec); // create a one to one table for mapping alleles to serotype for (String allele : hlaSpecs) { @@ -160,10 +194,20 @@ private static void put(Builder builder, String serotypeSpec, * explicit mapping exists. */ public static SeroType get(HLAType allele) { + HLAType manualAllele = allele; if (allele.spec().size() > 2) { - // All the equivalencies are based on 2-field alleles - allele = new HLAType(allele.locus(), allele.spec().subList(0, 2)); + // All the manual equivalencies are based on 2-field alleles + manualAllele = new HLAType(allele.locus(), allele.spec().subList(0, 2)); + } + if (manualEquivalencies.containsKey(manualAllele)) { + return manualEquivalencies.get(manualAllele); + } + if (careDxEquivalencies.containsKey(allele)) { + return careDxEquivalencies.get(allele); + } + if (careDxEquivalencies.containsKey(manualAllele)) { + return careDxEquivalencies.get(manualAllele); } - return manualEquivalencies.getOrDefault(allele, careDxEquivalencies.get(allele)); + return null; } } From 2b4ec33a64d25c212a9067bdf53c0918825486c3 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Tue, 28 May 2024 20:26:44 -0500 Subject: [PATCH 06/23] Abstract remapping processing, parse antigen values outside parens --- .../unet/deprecated/hla/Antigen.java | 6 +- .../jfx/StyleableContingentChoiceDialog.java | 1 + .../unet/jfx/wizard/FileInputController.java | 38 +- .../unet/model/ValidationModelBuilder.java | 859 +++--------------- .../model/remap/CancellationException.java | 11 + .../unet/model/remap/GUIRemapProcessor.java | 691 ++++++++++++++ .../unet/model/remap/RemapProcessor.java | 14 + .../unet/parser/HtmlDonorParser.java | 17 +- .../unet/parser/util/PdfSureTyperParser.java | 10 +- .../unet/parser/util/SerotypeEquivalence.java | 27 +- .../unet/parser/util/XmlDonorNetParser.java | 18 +- .../unet/parser/util/XmlScore6Parser.java | 34 +- .../unet/parser/util/XmlSureTyperParser.java | 10 +- .../integration/PdfSureTyperParserTest.java | 2 + .../unet/integration/XMLScore6ParserTest.java | 2 + .../integration/XMLSureTyperParserTest.java | 2 + 16 files changed, 945 insertions(+), 797 deletions(-) create mode 100644 src/main/java/org/pankratzlab/unet/model/remap/CancellationException.java create mode 100644 src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java create mode 100644 src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java index 60eff7d0..d876d2aa 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/Antigen.java @@ -231,8 +231,10 @@ private List parse(String[] p) { int[] iVal = new int[1]; Matcher matcher = SPEC_PATTERN.matcher(spec); matcher.find(); - // Extracts value from parentheses if they were present - String val = matcher.group(2) != null ? matcher.group(2) : matcher.group(1); + + // Extracts value outside of parentheses if they were present (changed from returning value + // inside parens, 5/24 - @rcoleb) + String val = matcher.group(1); if (val.contains(SPEC_DELIM)) { // Was passed XX:YY diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index fc41d402..530d82e9 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -39,6 +39,7 @@ * {@link #getResult()} when the dialog is dismissed. * @since JavaFX 8u40 */ +@SuppressWarnings("restriction") public class StyleableContingentChoiceDialog extends Dialog { /************************************************************************** diff --git a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java index f34fa52a..cfd8f807 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java +++ b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java @@ -25,7 +25,9 @@ import java.util.Objects; import java.util.Optional; import java.util.function.BiConsumer; +import org.pankratzlab.BackgroundDataProcessor; import org.pankratzlab.unet.deprecated.hla.CurrentDirectoryProvider; +import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.jfx.JFXPropertyHelper; import org.pankratzlab.unet.deprecated.jfx.JFXUtilHelper; import org.pankratzlab.unet.jfx.DonorNetUtils; @@ -33,6 +35,8 @@ import org.pankratzlab.unet.model.ValidationModelBuilder; import org.pankratzlab.unet.model.ValidationModelBuilder.ValidationResult; import org.pankratzlab.unet.model.ValidationTable; +import org.pankratzlab.unet.model.remap.GUIRemapProcessor; +import org.pankratzlab.unet.model.remap.GUIRemapProcessor.PresentableAlleleChoices; import org.pankratzlab.unet.parser.DonorFileParser; import org.pankratzlab.unet.parser.HtmlDonorParser; import org.pankratzlab.unet.parser.PdfDonorParser; @@ -170,15 +174,35 @@ private void selectDonorFile(ActionEvent event, DonorFileParser donorParser, // check for corrections - if (builder.hasCorrectionsIfSoStartLoading()) { - + if (builder.hasCorrections()) { + + BackgroundDataProcessor choiceSupplier = + new BackgroundDataProcessor<>(builder.getNonCWDLoci(), + (locus) -> PresentableAlleleChoices.create(locus, + builder.getAllelePairs(locus)), + (t) -> { + t.printStackTrace(); + return null; + }); + GUIRemapProcessor processor = new GUIRemapProcessor(choiceSupplier); Platform.runLater(() -> { - ValidationResult validationResult1 = builder.processCorrections(); - if (!validationResult1.valid) { - alertInvalid(donorParser, selectedFile, validationResult); - } else { - finish(donorParser, setter, linkedFile, selectedFile, builder); + try { + ValidationResult validationResult1 = builder.processCorrections(processor); + if (!validationResult1.valid) { + alertInvalid(donorParser, selectedFile, validationResult); + } else { + finish(donorParser, setter, linkedFile, selectedFile, builder); + } + } catch (Throwable e) { + Platform.runLater(() -> { + Alert alert = new Alert(AlertType.ERROR); + alert.setHeaderText(donorParser.getErrorText() + + "\nPlease notify the developers as this may indicate the data has changed." + + "\nOffending file: " + selectedFile.getName()); + alert.showAndWait(); + e.printStackTrace(); + }); } }); diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 400719ee..5a79ce96 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -21,8 +21,6 @@ */ package org.pankratzlab.unet.model; -import java.lang.reflect.Constructor; -import java.lang.reflect.Field; import java.math.BigDecimal; import java.util.ArrayList; import java.util.Arrays; @@ -41,14 +39,10 @@ import java.util.Optional; import java.util.Set; import java.util.TreeSet; -import java.util.function.Function; -import java.util.function.Predicate; -import java.util.function.Supplier; import java.util.stream.Collectors; import javax.swing.JFrame; import javax.swing.JOptionPane; import org.apache.commons.lang3.tuple.Pair; -import org.pankratzlab.BackgroundDataProcessor; import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.NullType; @@ -60,42 +54,25 @@ import org.pankratzlab.unet.hapstats.Haplotype; import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; -import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog; -import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog.Option; +import org.pankratzlab.unet.model.remap.CancellationException; +import org.pankratzlab.unet.model.remap.RemapProcessor; import org.pankratzlab.unet.parser.util.BwSerotypes; import org.pankratzlab.unet.parser.util.BwSerotypes.BwGroup; import org.pankratzlab.unet.parser.util.DRAssociations; import org.pankratzlab.unet.parser.util.RabinKarp; -import com.google.common.base.Predicates; import com.google.common.base.Strings; import com.google.common.collect.ArrayListMultimap; -import com.google.common.collect.BiMap; import com.google.common.collect.HashBasedTable; -import com.google.common.collect.HashBiMap; import com.google.common.collect.HashMultimap; import com.google.common.collect.ImmutableList; import com.google.common.collect.ImmutableMultimap; import com.google.common.collect.ImmutableSet; -import com.google.common.collect.ImmutableSortedSet; -import com.google.common.collect.LinkedListMultimap; import com.google.common.collect.ListMultimap; import com.google.common.collect.Lists; import com.google.common.collect.Multimap; import com.google.common.collect.MultimapBuilder; -import com.google.common.collect.MultimapBuilder.SortedSetMultimapBuilder; import com.google.common.collect.Sets; import com.google.common.collect.Table; -import javafx.geometry.Pos; -import javafx.scene.control.Label; -import javafx.scene.control.ListCell; -import javafx.scene.control.Tooltip; -import javafx.scene.layout.HBox; -import javafx.scene.layout.Priority; -import javafx.scene.layout.Region; -import javafx.scene.text.Text; -import javafx.scene.text.TextFlow; -import javafx.util.Duration; -import javafx.util.StringConverter; /** * Mutable builder class for creating a {@link ValidationModel}. @@ -131,12 +108,13 @@ public class ValidationModelBuilder { private Set aLocusCWD; private Set bLocusCWD; private Set cLocusCWD; - private Set aLocusCWDTypes; - private Set bLocusCWDTypes; - private Set cLocusCWDTypes; private Set aLocusFirst = new LinkedHashSet<>(); private Set bLocusFirst = new LinkedHashSet<>(); private Set cLocusFirst = new LinkedHashSet<>(); + + private Set aLocusCWDTypes; + private Set bLocusCWDTypes; + private Set cLocusCWDTypes; private Set aLocusFirstTypes; private Set bLocusFirstTypes; private Set cLocusFirstTypes; @@ -148,25 +126,27 @@ public class ValidationModelBuilder { private Map, Set>> remapping = new HashMap<>(); private Set drbLocus; - private Set dqaLocus; - private Set dqbLocus; - private Set dpaLocus; - // private Set drbLocusTypes; - private Set dqaLocusTypes; - private Set dqbLocusTypes; - private Set dpaLocusTypes; - private Set dpbLocusTypes; + private Set drbLocusNonCWD; + private Set dqaLocus; + private Set dqaLocusTypes; private Set dqaLocusTypesNonCWD; - private Set dqbLocusTypesNonCWD; - private Set dpaLocusTypesNonCWD; - private Set dpbLocusTypesNonCWD; - - private Set drbLocusNonCWD; private Set dqaLocusNonCWD; + + private Set dqbLocus; + private Set dqbLocusTypes; + private Set dqbLocusTypesNonCWD; private Set dqbLocusNonCWD; + + private Set dpaLocus; + private Set dpaLocusTypes; + private Set dpaLocusTypesNonCWD; private Set dpaLocusNonCWD; + + private Set dpbLocus; + private Set dpbLocusTypes; + private Set dpbLocusTypesNonCWD; private Set dpbLocusNonCWD; private Boolean bw4; @@ -383,20 +363,21 @@ public ValidationModelBuilder dpaNonCWD(String dpaType) { public ValidationModelBuilder dpbNonCWD(String dpbType) { dpbLocusNonCWD = makeIfNull(dpbLocusNonCWD); - // Shorten the allele designation to allele group and specific HLA protein. Further fields can - // not be entered into UNOS - if (!Strings.isNullOrEmpty(dpbType) && dpbType.matches(".*\\d.*")) { - HLAType tmpDPB1 = new HLAType(HLALocus.DPB1, dpbType); - if (tmpDPB1.spec().size() > 2) { - tmpDPB1 = - new HLAType(HLALocus.DPB1, new int[] {tmpDPB1.spec().get(0), tmpDPB1.spec().get(1)}); - } - dpbLocusNonCWD.add(tmpDPB1); - } + // // Shorten the allele designation to allele group and specific HLA protein. Further fields + // can + // // not be entered into UNOS + // if (!Strings.isNullOrEmpty(dpbType) && dpbType.matches(".*\\d.*")) { + HLAType tmpDPB1 = new HLAType(HLALocus.DPB1, dpbType); + // if (tmpDPB1.spec().size() > 2) { + // tmpDPB1 = + // new HLAType(HLALocus.DPB1, new int[] {tmpDPB1.spec().get(0), tmpDPB1.spec().get(1)}); + // } + dpbLocusNonCWD.add(tmpDPB1); + // } return this; } - public ValidationModelBuilder dqb(String dqbType) { + public ValidationModelBuilder dqbSerotype(String dqbType) { if (test2(dqbType)) { return null; } @@ -405,7 +386,7 @@ public ValidationModelBuilder dqb(String dqbType) { return this; } - public ValidationModelBuilder dqa(String dqaType) { + public ValidationModelBuilder dqaSerotype(String dqaType) { if (test2(dqaType)) { return null; } @@ -414,7 +395,7 @@ public ValidationModelBuilder dqa(String dqaType) { return this; } - public ValidationModelBuilder dpa(String dpaType) { + public ValidationModelBuilder dpaSerotype(String dpaType) { if (test2(dpaType)) { return null; } @@ -423,18 +404,23 @@ public ValidationModelBuilder dpa(String dpaType) { return this; } - public ValidationModelBuilder dpb(String dpbType) { + public ValidationModelBuilder dpb(HLAType dpbType) { dpbLocusTypes = makeIfNull(dpbLocusTypes); - // Shorten the allele designation to allele group and specific HLA protein. Further fields can - // not be entered into UNOS - if (!Strings.isNullOrEmpty(dpbType) && dpbType.matches(".*\\d.*")) { - HLAType tmpDPB1 = new HLAType(HLALocus.DPB1, dpbType); - if (tmpDPB1.spec().size() > 2) { - tmpDPB1 = - new HLAType(HLALocus.DPB1, new int[] {tmpDPB1.spec().get(0), tmpDPB1.spec().get(1)}); - } - dpbLocusTypes.add(tmpDPB1); - } + dpbLocusTypes.add(dpbType); + return this; + } + + public ValidationModelBuilder dpbSerotype(String dpbType) { + dpbLocus = makeIfNull(dpbLocus); + HLAType tmpDPB1 = new HLAType(HLALocus.DPB1, dpbType); + dpbLocus.add(trim(tmpDPB1)); + + return this; + } + + public ValidationModelBuilder dpbNonCIWD(HLAType dpbType) { + dpbLocusTypesNonCWD = makeIfNull(dpbLocusTypesNonCWD); + dpbLocusTypesNonCWD.add(dpbType); return this; } @@ -564,25 +550,6 @@ public void locusIsNonCIWD(HLAType locus) { nonCWDLoci.add(locus.locus()); } - private final class AlleleStringConverter extends StringConverter> { - private final PresentableAlleleChoices choices; - - private AlleleStringConverter(PresentableAlleleChoices choices) { - this.choices = choices; - } - - @Override - public String toString(Supplier object) { - final String selectedData = choices.getData(object); - return selectedData == null ? "" : selectedData; - } - - @Override - public Supplier fromString(String string) { - return choices.getPresentation(string); - } - } - public class ValidationResult { public final boolean valid; @@ -609,11 +576,34 @@ public ValidationModel build() { frequencyTable.clear(); ValidationModel validationModel = new ValidationModel(donorId, source, sourceType, aLocusCWD, - bLocusCWD, cLocusCWD, drbLocus, dqbLocus, dqaLocus, dpaLocus, dpbLocusTypes, bw4, bw6, + bLocusCWD, cLocusCWD, drbLocus, dqbLocus, dqaLocus, dpaLocus, getFinalDPBTypes(), bw4, bw6, dr51Locus, dr52Locus, dr53Locus, bcCwdHaplotypes, drDqDR345Haplotypes, remapping); return validationModel; } + // Shorten the allele designation to allele group and specific HLA protein. Further fields can + // not be entered into UNOS + private Set getFinalDPBTypes() { + Set dpbTypes = new HashSet<>(); + Set dpbSource = dpbLocusTypes; + if (dpbSource == null || dpbSource.isEmpty()) { + dpbSource = dpbLocus.stream().map(s -> new HLAType(HLALocus.DPB1, s.spec())) + .collect(ImmutableSet.toImmutableSet()); + } + for (HLAType dpbType1 : dpbSource) { + String dpbType = dpbType1.specString(); + if (!Strings.isNullOrEmpty(dpbType) && dpbType.matches(".*\\d.*")) { + HLAType tmpDPB1 = new HLAType(HLALocus.DPB1, dpbType); + if (tmpDPB1.spec().size() > 2) { + tmpDPB1 = + new HLAType(HLALocus.DPB1, new int[] {tmpDPB1.spec().get(0), tmpDPB1.spec().get(1)}); + } + dpbTypes.add(tmpDPB1); + } + } + return dpbTypes; + } + /** * Helper method to build the B/C haplotypes. Extra filtering is needed based on the Bw groups. */ @@ -948,14 +938,14 @@ private void pruneUnknown(Multimap typesForStrand) { private ValidationResult ensureValidity() { // Ensure all fields have been set for (Object o : Lists.newArrayList(donorId, source, aLocusCWD, bLocusCWD, cLocusCWD, drbLocus, - dqbLocus, dqaLocus, dpbLocusTypes, bw4, bw6)) { + dqbLocus, dqaLocus, getFinalDPBTypes(), bw4, bw6)) { if (Objects.isNull(o)) { return new ValidationResult(false, Optional.of("ValidationModel incomplete")); } } // Ensure all sets have a reasonable number of entries for (Set set : ImmutableList.of(aLocusCWD, bLocusCWD, cLocusCWD, drbLocus, dqbLocus, - dqaLocus, dpbLocusTypes)) { + dqaLocus, getFinalDPBTypes())) { if (set.isEmpty() || set.size() > 2) { return new ValidationResult(false, Optional.of("ValidationModel contains invalid allele count: " + set)); @@ -978,26 +968,11 @@ private ValidationResult ensureValidity() { return new ValidationResult(true, Optional.empty()); } - BackgroundDataProcessor choiceSupplier; - public boolean hasCorrections() { return !nonCWDLoci.isEmpty(); } - public boolean hasCorrectionsIfSoStartLoading() { - if (hasCorrections()) { - // start loading data in the background - choiceSupplier = new BackgroundDataProcessor<>(nonCWDLoci, - (locus) -> PresentableAlleleChoices.create(locus, getAllelePairs(locus)), (t) -> { - t.printStackTrace(); - return null; - }); - return true; - } - return false; - } - - public ValidationResult processCorrections() { + public ValidationResult processCorrections(RemapProcessor remapProcessor) { boolean cancelled = false; @@ -1005,9 +980,11 @@ public ValidationResult processCorrections() { Pair, Set> remapPair = null; try { - remapPair = processRemap(locus, this); + remapPair = remapProcessor.processRemapping(locus, this); } catch (CancellationException e) { cancelled = true; + } catch (Throwable t) { + t.printStackTrace(); } if (remapPair != null) { @@ -1022,21 +999,6 @@ public ValidationResult processCorrections() { return new ValidationResult(true, Optional.empty()); } - private class CancellationException extends RuntimeException { - - private static final long serialVersionUID = 1L; - - // used to indicate user-cancellation of locus remapping - - } - - interface RemapProcessor { - - public Pair, Set> processRemapping(HLALocus locus, - ValidationModelBuilder builder) throws CancellationException; - - } - public Set getCWDSeroTypesForLocus(HLALocus locus) { switch (locus) { @@ -1051,9 +1013,14 @@ public Set getCWDSeroTypesForLocus(HLALocus locus) { case DQA1: return dqaLocus; case DPB1: - return null; + return dpbLocus; case DQB1: return dqbLocus; + case DRB1: + case DRB3: + case DRB4: + case DRB5: + return drbLocus; default: return null; } @@ -1074,16 +1041,38 @@ public Set getAllSeroTypesForLocus(HLALocus locus) { case DQA1: return dqaLocusNonCWD; case DPB1: - return dpbLocusNonCWD.stream().map(HLAType::equivSafe) - .collect(ImmutableSet.toImmutableSet()); + return trim(dpbLocusNonCWD); case DQB1: return dqbLocusNonCWD; + case DRB1: + case DRB3: + case DRB4: + case DRB5: + return drbLocusNonCWD; default: return null; } } + private Set trim(Set set) { + return set.stream().map(this::trim).collect(Collectors.toCollection(HashSet::new)); + } + + private SeroType trim(HLAType hlaType) { + List seroStr = new ArrayList<>(); + seroStr.add(String.valueOf(hlaType.spec().get(0))); + + if (Objects.equals(HLALocus.DPA1, hlaType.locus()) + || Objects.equals(HLALocus.DPB1, hlaType.locus())) { + // DPA and DPB report two fields + seroStr.add(String.valueOf(hlaType.spec().get(1))); + } + + String[] array = seroStr.toArray(new String[seroStr.size()]); + return new SeroType(hlaType.locus().sero(), array); + } + public Set getCWDTypesForLocus(HLALocus locus) { switch (locus) { @@ -1101,6 +1090,10 @@ public Set getCWDTypesForLocus(HLALocus locus) { return dpbLocusTypes; case DQB1: return dqbLocusTypes; + case DRB1: + case DRB3: + case DRB4: + case DRB5: default: return null; } @@ -1123,627 +1116,27 @@ public Set getAllTypesForLocus(HLALocus locus) { return dpbLocusTypesNonCWD; case DQB1: return dqbLocusTypesNonCWD; + case DRB1: + case DRB3: + case DRB4: + case DRB5: default: return null; } } - private AllelePairings getPossibleAllelePairsForLocus(HLALocus locus) { + public AllelePairings getPossibleAllelePairsForLocus(HLALocus locus) { return possibleAllelePairings.get(locus); } - private AllelePairings getDonorAllelePairsForLocus(HLALocus locus) { + public AllelePairings getDonorAllelePairsForLocus(HLALocus locus) { return donorAllelePairings.get(locus); } - private static class GUIRemapProcessor implements RemapProcessor { - - private Pair, Set> processRemap(HLALocus locus, - ValidationModelBuilder builder) { - AllelePairings allelePairs = builder.getPossibleAllelePairsForLocus(locus); - AllelePairings donorPairs = builder.getDonorAllelePairsForLocus(locus); - - Set locusSet = builder.getCWDSeroTypesForLocus(locus); - Set locusSetNonCWD = builder.getAllSeroTypesForLocus(locus); - Set typesSet = builder.getCWDTypesForLocus(locus); - Set typesSetNonCWD = builder.getAllTypesForLocus(locus); - - if (allelePairs == null || donorPairs == null) { - // TODO - return null; - } - - // FIXME TODO this needs to be done on a Task thread to show a progress spinner if it blocks - // while loading. However, the choice dialogs need to be created on the JavaFX thread. - // But also, this method overall needs to return a single validation result object ... - PresentableAlleleChoices choices = choiceSupplier.get(locus); - - Iterator typeIter; - Iterator seroIter; - - typeIter = typesSet.iterator(); - HLAType hlaType1_CIWD = typeIter.next(); - HLAType hlaType2_CIWD = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; - - // seroIter = locusSet.iterator(); - // SeroType seroType1_CIWD = seroIter.next(); - // SeroType seroType2_CIWD = seroIter.hasNext() ? seroIter.next() : seroType1_CIWD; - - typeIter = typesSetNonCWD.iterator(); - HLAType hlaType1_First = typeIter.next(); - HLAType hlaType2_First = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; - - seroIter = locusSetNonCWD.iterator(); - SeroType seroType1_First = seroIter.next(); - SeroType seroType2_First = seroIter.hasNext() ? seroIter.next() : seroType1_First; - - // TODO encapsulate Allele selection JavaFX components in a different class in the JFX - // packages - // ValidationModelBuilder shouldn't know about JavaFX UI components - - HBox assignedPane = new HBox(10); - assignedPane.setMaxWidth(Double.MAX_VALUE); - assignedPane.setAlignment(Pos.CENTER_LEFT); - Label assignedHeader = new Label("Assigned allele pair: "); - TextFlow assignedTextFlow = new TextFlow(); - addTextNodes(assignedTextFlow, hlaType1_First.toString(), true); - assignedTextFlow.getChildren().add(new Text(" | ")); - addTextNodes(assignedTextFlow, hlaType2_First.toString(), true); - Label assignedHeaderLbl = new Label("", assignedTextFlow); - assignedHeaderLbl.setMaxWidth(Double.MAX_VALUE); - assignedHeaderLbl.setMaxHeight(Double.MAX_VALUE); - assignedPane.getChildren().add(assignedHeader); - assignedPane.getChildren().add(getSpacer()); - assignedPane.getChildren().add(assignedHeaderLbl); - - HBox ciwdPane = new HBox(10); - ciwdPane.setMaxWidth(Double.MAX_VALUE); - ciwdPane.setAlignment(Pos.CENTER_LEFT); - Label ciwdHeader = new Label("Common / Well-Documented allele pair: "); - TextFlow ciwdTextFlow = new TextFlow(); - addTextNodes(ciwdTextFlow, hlaType1_CIWD.toString(), true); - ciwdTextFlow.getChildren().add(new Text(" | ")); - addTextNodes(ciwdTextFlow, hlaType2_CIWD.toString(), true); - Label ciwdHeaderLbl = new Label("", ciwdTextFlow); - ciwdHeaderLbl.setMaxWidth(Double.MAX_VALUE); - ciwdHeaderLbl.setMaxHeight(Double.MAX_VALUE); - ciwdPane.getChildren().add(ciwdHeader); - ciwdPane.getChildren().add(getSpacer()); - ciwdPane.getChildren().add(ciwdHeaderLbl); - - String text = "Or manually select allele pair for this locus"; - String text1 = - "(selecting the first allele will populate valid pairings for the second allele)"; - - final List> allChoices = choices.getAllChoices(); - - Function, String> tooltipProvider = (tf) -> { - return Objects.toString(choices.dataMap.get(tf), null); - }; - - String filterName = "Show CIWD Alleles Only"; - Predicate> filter = (tf) -> { - return isAnyPartCWD(choices.getData(tf)); - }; - - StyleableContingentChoiceDialog.Option> opt1 = - new Option<>(assignedPane, choices.getChoiceForAllele(hlaType1_First.toString()), - choices.getChoiceForAllele(hlaType2_First.toString())); - - StyleableContingentChoiceDialog.Option> opt2 = - new Option<>(ciwdPane, choices.getChoiceForAllele(hlaType1_CIWD.toString()), - choices.getChoiceForAllele(hlaType2_CIWD.toString())); - - Label manualChoice = new Label(text + System.lineSeparator() + text1); - - StyleableContingentChoiceDialog> cd = - new StyleableContingentChoiceDialog<>(null, allChoices, Lists.newArrayList(), - choices.getAllSecondChoices(), choices.dataMap, filterName, - filter/* , textEntryMatcher */, opt1, opt2, manualChoice); - cd.setTitle("Select HLA-" + locus.name() + " Alleles"); - - cd.setHeaderText("Assigned allele pair for HLA-" + locus.name() - + " locus is not Common / Well-Documented."); - cd.setContentText("Please select desired allele pair for this locus:"); - - cd.setCombo1CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo1ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo2CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); - cd.setCombo2ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); - cd.setConverter1(new AlleleStringConverter(choices)); - cd.setConverter2(new AlleleStringConverter(choices)); - - Optional> result = cd.showAndWait(); - - if (!result.isPresent()) { - throw new CancellationException(); - } - - Supplier selAllele1 = result.get(); - Supplier selAllele2 = cd.getSelectedSecondItem(); - - String allele1 = choices.getData(selAllele1); - String allele2 = choices.getData(selAllele2); - - HLAType hlaType1 = HLAType.valueOf(allele1); - HLAType hlaType2 = HLAType.valueOf(allele2); - SeroType seroType1 = hlaType1.equivSafe(); - SeroType seroType2 = hlaType2.equivSafe(); - - locusSet.clear(); - locusSet.add(seroType1); - locusSet.add(seroType2); - typesSet.clear(); - typesSet.add(hlaType1); - typesSet.add(hlaType2); - - boolean a1Match = - hlaType1.compareTo(hlaType1_First) == 0 || hlaType1.compareTo(hlaType2_First) == 0; - boolean a2Match = - hlaType2.compareTo(hlaType1_First) == 0 || hlaType2.compareTo(hlaType2_First) == 0; - - if (!a1Match || !a2Match) { - ImmutableSortedSet prevSet = - ImmutableSortedSet.of(new TypePair(hlaType1_First, seroType1_First), - new TypePair(hlaType2_First, seroType2_First)); - - ImmutableSortedSet newSet = ImmutableSortedSet - .of(new TypePair(hlaType1, seroType1), new TypePair(hlaType2, seroType2)); - - - return Pair.of(prevSet, newSet); - } - - return null; - } - } - - private Region getSpacer() { - Region spacer = new Region(); - HBox.setHgrow(spacer, Priority.ALWAYS); - return spacer; - } - - private AllelePairings getAllelePairs(HLALocus locus) { + public AllelePairings getAllelePairs(HLALocus locus) { return possibleAllelePairings.get(locus); } - public abstract static class PresentableDataChoices { - List choices; - Multimap secondChoices; - BiMap dataMap; - - public PresentableDataChoices(List choices, Multimap secondChoices, - BiMap presentationToDataMap) { - this.choices = choices; - this.secondChoices = secondChoices; - this.dataMap = presentationToDataMap; - } - - public List getAllChoices() { - return choices; - } - - public Multimap getAllSecondChoices() { - return secondChoices; - } - - public Collection getSecondChoices(T firstChoice) { - return secondChoices.get(firstChoice); - } - - public abstract List getMatchingChoices(String userInput); - - public R getData(T presentable) { - return dataMap.get(presentable); - } - - public T getPresentation(R data) { - return dataMap.inverse().get(data); - } - - } - - public static class PresentableAlleleChoices - extends PresentableDataChoices, String> { - - public static PresentableAlleleChoices create(HLALocus locus, AllelePairings allelePairings) { - - List> userChoices = new ArrayList<>(); - ListMultimap, Supplier> secondChoices = - SortedSetMultimapBuilder.hashKeys().arrayListValues().build(); - BiMap, String> presentationToDataMap = HashBiMap.create(); - - List alleleKeys = new ArrayList<>(allelePairings.map.keySet()); - sortAlleleStrings(alleleKeys); - - LinkedListMultimap choiceList = - condenseIntoGroups(allelePairings, alleleKeys, true); - - for (String allele : choiceList.keySet()) { - Supplier supp = () -> getText(allele); - - userChoices.add(supp); - presentationToDataMap.put(supp, allele); - } - - - for (Supplier choice : userChoices) { - String data = presentationToDataMap.get(choice); - if (data == null) { - continue; - } - String pairingAllele = data.contains("-") ? data.split("-")[0] : data; - - List pairings = new ArrayList<>(allelePairings.getValidPairings(pairingAllele)); - sortAlleleStrings(pairings); - - LinkedListMultimap secondChoicePairings = - condenseIntoGroups(allelePairings, pairings, false); - - for (String pairing : secondChoicePairings.keySet()) { - Supplier presentationView = presentationToDataMap.inverse().get(pairing); - if (presentationView == null) { - presentationView = () -> getText(pairing); - presentationToDataMap.put(presentationView, pairing); - } - secondChoices.put(choice, presentationView); - } - } - - Map alleleToGroupMap = new HashMap<>(); - choiceList.entries().stream().forEach(e -> { - alleleToGroupMap.put(e.getValue(), e.getKey()); - }); - - return new PresentableAlleleChoices(userChoices, secondChoices, presentationToDataMap, - allelePairings, alleleToGroupMap); - } - - private static LinkedListMultimap condenseIntoGroups( - AllelePairings allelePairings, List alleleKeys, boolean checkPairings) { - - List> subsets = new ArrayList<>(); - List subset = new ArrayList<>(); - - HLAType prev3FieldType = null; - - // all allele strings should be in the correct order now - // now let's condense into subsets of the same serotypes, with - // separate subsets for N/n and LSCAQ/lscaq alleles - for (String allele : alleleKeys) { - if (allele.matches(NOT_EXPRESSED) || allele.matches(NOT_ON_CELL_SURFACE)) { - // make sure to add the currently-being-built subset first! - if (subset.size() > 0) { - subsets.add(subset); - subset = new ArrayList<>(); - } - // add null or lscaq alleles as single entries - subsets.add(Lists.newArrayList(allele)); - // clear out known three-field type - prev3FieldType = null; - continue; - } - - HLAType hType = HLAType.valueOf(allele); - if (hType.resolution() <= 2) { - // make sure to add the currently-being-built subset first! - if (subset.size() > 0) { - subsets.add(subset); - subset = new ArrayList<>(); - } - // add two-field alleles as single entries - subsets.add(Lists.newArrayList(allele)); - // clear out known three-field type - prev3FieldType = null; - continue; - } - - // we know resolution is >= 3 - - HLAType curr3FieldType = (hType.resolution() == 3) ? hType - : new HLAType(hType.locus(), hType.spec().get(0), hType.spec().get(1), - hType.spec().get(2)); - if (prev3FieldType != null && prev3FieldType.compareTo(curr3FieldType) != 0) { - // new three field type - subsets.add(subset); - subset = new ArrayList<>(); - } - // same or new three-field type, either way: - // update known three-field type, and - // add four-field type to subset - prev3FieldType = curr3FieldType; - subset.add(allele); - - } - if (subset.size() > 0) { - subsets.add(subset); - } - - LinkedListMultimap groupToAllelesMap = LinkedListMultimap.create(); - - // now we need to process the subset lists - // single element subsets can be added directly - // -- this preserves null/not-expressed subsets - // multiple element subsets need to be further - // separated into subsets: all alleles in a subset must - // map to the same serotype and the same second choice alleles - - for (List sub : subsets) { - if (sub.size() == 1) { - groupToAllelesMap.put(sub.get(0), sub.get(0)); - continue; - } - - List> subSubsets = new ArrayList<>(); - List subSubset = new ArrayList<>(); - - SeroType prevSero = null; - Set prevPairings = null; - - for (String subAllele : sub) { - HLAType type = HLAType.valueOf(subAllele); - SeroType newSero = type.equivSafe(); - HashSet newPairings = - checkPairings ? Sets.newHashSet(allelePairings.getValidPairings(subAllele)) - : new HashSet<>(); - if (prevSero == null) { - prevSero = newSero; - prevPairings = newPairings; - } else if (prevSero.compareTo(newSero) != 0) { - if (subSubset.size() > 0) { - subSubsets.add(subSubset); - subSubset = new ArrayList<>(); - } - prevSero = newSero; - prevPairings = newPairings; - } else if (!prevPairings.containsAll(newPairings) - || !newPairings.containsAll(prevPairings)) { - if (subSubset.size() > 0) { - subSubsets.add(subSubset); - subSubset = new ArrayList<>(); - } - prevSero = newSero; - prevPairings = newPairings; - } - subSubset.add(subAllele); - } - if (subSubset.size() > 0) { - subSubsets.add(subSubset); - subSubset = new ArrayList<>(); - } - - for (List subS : subSubsets) { - if (subS.size() == 1) { - groupToAllelesMap.put(subS.get(0), subS.get(0)); - } else { - String groupName = subS.get(0) + "-" + subS.get(subS.size() - 1); - for (String s : subS) { - groupToAllelesMap.put(groupName, s); - } - } - } - } - - return groupToAllelesMap; - } - - private static void sortAlleleStrings(List alleleKeys) { - alleleKeys.sort((s1, s2) -> { - boolean check1N = s1.matches(NOT_EXPRESSED); - boolean check1C = s1.matches(NOT_ON_CELL_SURFACE); - boolean check2N = s2.matches(NOT_EXPRESSED); - boolean check2C = s2.matches(NOT_ON_CELL_SURFACE); - boolean check1 = check1N || check1C; - boolean check2 = check2N || check2C; - // char s1C = s1.charAt(s1.length() - 1); - // char s2C = s2.charAt(s2.length() - 1); - String s1Hs = check1 ? s1.substring(0, s1.length() - 1) : s1; - String s2Hs = check2 ? s2.substring(0, s2.length() - 1) : s2; - - HLAType h1 = HLAType.valueOf(s1Hs); - HLAType h2 = HLAType.valueOf(s2Hs); - - int comp; - if ((comp = h1.compareTo(h2)) != 0) - return comp; - - if (check1 && !check2) { - // first element ends with special character, meaning second element should come first - return 1; - } else if (check2 && !check1) { - // second element ends with special character, meaning first element should come first - return -1; - } - - // both end with a special character - if (check1N && check2N) { - // both null and same HLAType - these are the same allele - return 0; - } else if (check1N && !check2N) { - // first element is null, second is lscaq, second comes first - return 1; - } else if (!check1N && check2N) { - // first element is lscaq, second is null, first comes first - return -1; - } - - - // this block could probably be condensed based on knowing null status from previous checks, - // but it's easier to just duplicate the logic for now... - - // both end with a special character - if (check1C && check2C) { - // both null and same HLAType - these are the same allele - return 0; - } else if (check1C && !check2C) { - // first element is null, second is lscaq, second comes first - return 1; - } else if (!check1C && check2C) { - // first element is lscaq, second is null, first comes first - return -1; - } - - // TODO dunno what's going on here... probably should do something special? - return 0; - }); - } - - private final AllelePairings allelePairs; - - Map alleleToGroupKeyMap; - - public Supplier getChoiceForAllele(String allele) { - return getPresentation(alleleToGroupKeyMap.get(allele)); - } - - private PresentableAlleleChoices(List> choices, - Multimap, Supplier> secondChoices, - BiMap, String> presentationToDataMap, AllelePairings allelePairs, - Map alleleToGroupMap) { - super(choices, secondChoices, presentationToDataMap); - this.allelePairs = allelePairs; - this.alleleToGroupKeyMap = alleleToGroupMap; - } - - @Override - public List> getMatchingChoices(String userInput) { - return allelePairs.getMatchingAlleles(userInput).stream().map(s -> dataMap.inverse().get(s)) - .filter(Predicates.notNull()).collect(Collectors.toList()); - } - - } - - private static TextFlow getText(String allele) { - TextFlow flow = new TextFlow(); - if (allele.contains("-")) { - String[] a = allele.split("-"); - addTextNodes(flow, a[0], false); - flow.getChildren().add(new Text(" - ")); - addTextNodes(flow, a[1], true); - } else { - addTextNodes(flow, allele, true); - } - - return flow; - } - - private boolean isAnyPartCWD(String allele) { - HLAType alleleType = HLAType.valueOf(allele); - Status status1 = CommonWellDocumented.getStatus(alleleType); - - return status1 != Status.UNKNOWN; - } - - private static void addTextNodes(TextFlow flow, final String allele, boolean addSero) { - HLAType alleleType = HLAType.valueOf(allele); - HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); - Status status1 = CommonWellDocumented.getStatus(alleleType); - - flow.getChildren().add(new Text(alleleType.locus().name() + "*")); - - String specString = alleleType.specString(); - boolean match = allele.matches(NOT_EXPRESSED) || allele.matches(NOT_ON_CELL_SURFACE); - - if (status1 != Status.UNKNOWN) { - - if (cwdType1.specString().length() < specString.length()) { - Text t1 = new Text(cwdType1.specString()); - t1.setStyle("-fx-font-weight:bold;"); - flow.getChildren().add(t1); - flow.getChildren().add(new Text(specString.substring(cwdType1.specString().length()))); - } else { - Text t1 = new Text(specString); - t1.setStyle("-fx-font-weight:bold;"); - flow.getChildren().add(t1); - } - - if (match) { - flow.getChildren().add(new Text("" + allele.charAt(allele.length() - 1))); - } - - } else { - flow.getChildren() - .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); - } - - if (addSero) { - flow.getChildren().add( - new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); - } - } - - private static class SimpleTableObjectListCell extends ListCell> { - - // private Function, Supplier> tooltipProvider; - private Function, String> tooltipProvider; - private Tooltip tooltip = new Tooltip(); - - public SimpleTableObjectListCell(Function, String> tooltipProvider) { - // Function, Supplier> tooltipProvider) { - this.tooltipProvider = tooltipProvider; - - // hack for adjusting tooltip delay / etc - // from https://stackoverflow.com/a/43291239/875496 - // TODO FIXME change when JavaFX9+ is available - try { - Class clazz = tooltip.getClass().getDeclaredClasses()[0]; - Constructor constructor = clazz.getDeclaredConstructor(Duration.class, Duration.class, - Duration.class, boolean.class); - constructor.setAccessible(true); - Object tooltipBehavior = constructor.newInstance(new Duration(50), // open - new Duration(500000), // visible - new Duration(100), // close - false); - Field fieldBehavior = tooltip.getClass().getDeclaredField("BEHAVIOR"); - fieldBehavior.setAccessible(true); - fieldBehavior.set(tooltip, tooltipBehavior); - } catch (Throwable t) { - t.printStackTrace(); - } - - tooltip.setWrapText(true); - tooltip.setMaxWidth(600); - - /* - * NB: TODO FIXME setting style here because I couldn't figure out how to locate it in an - * actual CSS style sheet -- 04-18-2024, b.cole - */ - tooltip.setStyle( - "-fx-background: rgba(230,230,230); -fx-text-fill: black; -fx-background-color: rgba(230,230,230,0.95); -fx-background-radius: 5px; -fx-background-insets: 0; -fx-padding: 0.667em 0.75em 0.667em 0.75em; -fx-effect: dropshadow( three-pass-box , rgba(0,0,0,0.5) , 10, 0.0 , 0 , 3 ); -fx-font-size: 0.95em;"); - } - - @Override - public void updateItem(Supplier item, boolean empty) { - try { - super.updateItem(item, empty); - if (item != null && !empty) { - setGraphic(item.get()); - - String tf = tooltipProvider.apply(item); - // Supplier tf = tooltipProvider.apply(item); - if (tf == null || tf.length() < 150) { - // TODO don't show tooltips if item isn't too long! - setTooltip(null); - } else { - // System.out.println("tool:: " + tf); - tooltip.setText(tf); - // final TextFlow value = tf.get(); - // value.setMaxWidth(tooltip.getMaxWidth()); - // tooltip.setGraphic(value); - setTooltip(tooltip); - } - } else { - setGraphic(null); - setTooltip(null); - } - } catch (Throwable t) { - t.printStackTrace(); - } - } - - } - /** Helper method to build a set if it's null */ private Set makeIfNull(Set locusSet) { if (Objects.isNull(locusSet)) { @@ -1783,6 +1176,10 @@ public void addPairing(String a1, String a2) { map.put(a2, a1); } + public Set getAlleleKeys() { + return map.keySet(); + } + public Collection getValidPairings(String allele) { return map.get(allele); } @@ -1976,4 +1373,8 @@ private List makeList(Collection haplotypes) { return sorted; } } + + public Set getNonCWDLoci() { + return nonCWDLoci; + } } diff --git a/src/main/java/org/pankratzlab/unet/model/remap/CancellationException.java b/src/main/java/org/pankratzlab/unet/model/remap/CancellationException.java new file mode 100644 index 00000000..fa1bad6c --- /dev/null +++ b/src/main/java/org/pankratzlab/unet/model/remap/CancellationException.java @@ -0,0 +1,11 @@ +package org.pankratzlab.unet.model.remap; + +/** + * Used to indicate user-cancellation of locus remapping + */ +public class CancellationException extends RuntimeException { + + private static final long serialVersionUID = 1L; + + +} \ No newline at end of file diff --git a/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java new file mode 100644 index 00000000..a79b78c8 --- /dev/null +++ b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java @@ -0,0 +1,691 @@ +package org.pankratzlab.unet.model.remap; + +import java.lang.reflect.Constructor; +import java.lang.reflect.Field; +import java.util.ArrayList; +import java.util.Collection; +import java.util.HashMap; +import java.util.HashSet; +import java.util.Iterator; +import java.util.List; +import java.util.Map; +import java.util.Objects; +import java.util.Optional; +import java.util.Set; +import java.util.function.Function; +import java.util.function.Predicate; +import java.util.function.Supplier; +import java.util.stream.Collectors; +import org.apache.commons.lang3.tuple.Pair; +import org.pankratzlab.BackgroundDataProcessor; +import org.pankratzlab.unet.deprecated.hla.HLALocus; +import org.pankratzlab.unet.deprecated.hla.HLAType; +import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; +import org.pankratzlab.unet.hapstats.CommonWellDocumented.Status; +import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog; +import org.pankratzlab.unet.jfx.StyleableContingentChoiceDialog.Option; +import org.pankratzlab.unet.model.ValidationModelBuilder; +import org.pankratzlab.unet.model.ValidationModelBuilder.AllelePairings; +import org.pankratzlab.unet.model.ValidationModelBuilder.TypePair; +import com.google.common.base.Predicates; +import com.google.common.collect.BiMap; +import com.google.common.collect.HashBiMap; +import com.google.common.collect.ImmutableSortedSet; +import com.google.common.collect.LinkedListMultimap; +import com.google.common.collect.ListMultimap; +import com.google.common.collect.Lists; +import com.google.common.collect.Multimap; +import com.google.common.collect.MultimapBuilder.SortedSetMultimapBuilder; +import com.google.common.collect.Sets; +import javafx.geometry.Pos; +import javafx.scene.control.Label; +import javafx.scene.control.ListCell; +import javafx.scene.control.Tooltip; +import javafx.scene.layout.HBox; +import javafx.scene.layout.Priority; +import javafx.scene.layout.Region; +import javafx.scene.text.Text; +import javafx.scene.text.TextFlow; +import javafx.util.Duration; +import javafx.util.StringConverter; + +public class GUIRemapProcessor implements RemapProcessor { + + private final BackgroundDataProcessor choiceSupplier; + + public GUIRemapProcessor( + BackgroundDataProcessor choiceSupplier) { + this.choiceSupplier = choiceSupplier; + } + + @Override + public Pair, Set> processRemapping(HLALocus locus, + ValidationModelBuilder builder) throws CancellationException { + AllelePairings allelePairs = builder.getPossibleAllelePairsForLocus(locus); + AllelePairings donorPairs = builder.getDonorAllelePairsForLocus(locus); + + Set locusSet = builder.getCWDSeroTypesForLocus(locus); + Set locusSetNonCWD = builder.getAllSeroTypesForLocus(locus); + Set typesSet = builder.getCWDTypesForLocus(locus); + Set typesSetNonCWD = builder.getAllTypesForLocus(locus); + + if (allelePairs == null || donorPairs == null) { + // TODO + System.out.println("No allele pairs for locus " + locus); + return null; + } + if (typesSetNonCWD == null || typesSetNonCWD.isEmpty()) { + // TODO + System.out.println("No types for locus " + locus); + return null; + } + + // FIXME TODO this needs to be done on a Task thread to show a progress spinner if it blocks + // while loading. However, the choice dialogs need to be created on the JavaFX thread. + // But also, this method overall needs to return a single validation result object ... + GUIRemapProcessor.PresentableAlleleChoices choices = choiceSupplier.get(locus); + + Iterator typeIter; + Iterator seroIter; + + typeIter = typesSet.iterator(); + HLAType hlaType1_CIWD = typeIter.next(); + HLAType hlaType2_CIWD = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; + + // seroIter = locusSet.iterator(); + // SeroType seroType1_CIWD = seroIter.next(); + // SeroType seroType2_CIWD = seroIter.hasNext() ? seroIter.next() : seroType1_CIWD; + + typeIter = typesSetNonCWD.iterator(); + HLAType hlaType1_First = typeIter.next(); + HLAType hlaType2_First = typeIter.hasNext() ? typeIter.next() : hlaType1_CIWD; + + seroIter = locusSetNonCWD.iterator(); + SeroType seroType1_First = seroIter.next(); + SeroType seroType2_First = seroIter.hasNext() ? seroIter.next() : seroType1_First; + + HBox assignedPane = new HBox(10); + assignedPane.setMaxWidth(Double.MAX_VALUE); + assignedPane.setAlignment(Pos.CENTER_LEFT); + Label assignedHeader = new Label("Assigned allele pair: "); + TextFlow assignedTextFlow = new TextFlow(); + addTextNodes(assignedTextFlow, hlaType1_First.toString(), true); + assignedTextFlow.getChildren().add(new Text(" | ")); + addTextNodes(assignedTextFlow, hlaType2_First.toString(), true); + Label assignedHeaderLbl = new Label("", assignedTextFlow); + assignedHeaderLbl.setMaxWidth(Double.MAX_VALUE); + assignedHeaderLbl.setMaxHeight(Double.MAX_VALUE); + assignedPane.getChildren().add(assignedHeader); + assignedPane.getChildren().add(getSpacer()); + assignedPane.getChildren().add(assignedHeaderLbl); + + HBox ciwdPane = new HBox(10); + ciwdPane.setMaxWidth(Double.MAX_VALUE); + ciwdPane.setAlignment(Pos.CENTER_LEFT); + Label ciwdHeader = new Label("Common / Well-Documented allele pair: "); + TextFlow ciwdTextFlow = new TextFlow(); + addTextNodes(ciwdTextFlow, hlaType1_CIWD.toString(), true); + ciwdTextFlow.getChildren().add(new Text(" | ")); + addTextNodes(ciwdTextFlow, hlaType2_CIWD.toString(), true); + Label ciwdHeaderLbl = new Label("", ciwdTextFlow); + ciwdHeaderLbl.setMaxWidth(Double.MAX_VALUE); + ciwdHeaderLbl.setMaxHeight(Double.MAX_VALUE); + ciwdPane.getChildren().add(ciwdHeader); + ciwdPane.getChildren().add(getSpacer()); + ciwdPane.getChildren().add(ciwdHeaderLbl); + + String text = "Or manually select allele pair for this locus"; + String text1 = + "(selecting the first allele will populate valid pairings for the second allele)"; + + final List> allChoices = choices.getAllChoices(); + + Function, String> tooltipProvider = (tf) -> { + return Objects.toString(choices.dataMap.get(tf), null); + }; + + String filterName = "Show CIWD Alleles Only"; + Predicate> filter = (tf) -> { + return isAnyPartCWD(choices.getData(tf)); + }; + + StyleableContingentChoiceDialog.Option> opt1 = + new Option<>(assignedPane, choices.getChoiceForAllele(hlaType1_First.toString()), + choices.getChoiceForAllele(hlaType2_First.toString())); + + final Supplier choiceForAllele1 = + choices.getChoiceForAllele(hlaType1_CIWD.toString()); + final Supplier choiceForAllele2 = + choices.getChoiceForAllele(hlaType2_CIWD.toString()); + StyleableContingentChoiceDialog.Option> opt2 = + new Option<>(ciwdPane, choiceForAllele1, choiceForAllele2); + + Label manualChoice = new Label(text + System.lineSeparator() + text1); + + StyleableContingentChoiceDialog> cd = new StyleableContingentChoiceDialog<>( + null, allChoices, Lists.newArrayList(), choices.getAllSecondChoices(), choices.dataMap, + filterName, filter/* , textEntryMatcher */, opt1, opt2, manualChoice); + cd.setTitle("Select HLA-" + locus.name() + " Alleles"); + + cd.setHeaderText( + "Assigned allele pair for HLA-" + locus.name() + " locus is not Common / Well-Documented."); + cd.setContentText("Please select desired allele pair for this locus:"); + + cd.setCombo1CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo1ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo2CellFactory(listView -> new SimpleTableObjectListCell(tooltipProvider)); + cd.setCombo2ButtonCell(new SimpleTableObjectListCell(tooltipProvider)); + cd.setConverter1(new AlleleStringConverter(choices)); + cd.setConverter2(new AlleleStringConverter(choices)); + + Optional> result = cd.showAndWait(); + + if (!result.isPresent()) { + throw new CancellationException(); + } + + Supplier selAllele1 = result.get(); + Supplier selAllele2 = cd.getSelectedSecondItem(); + + String allele1 = choices.getData(selAllele1); + String allele2 = choices.getData(selAllele2); + + HLAType hlaType1 = HLAType.valueOf(allele1); + HLAType hlaType2 = HLAType.valueOf(allele2); + SeroType seroType1 = hlaType1.equivSafe(); + SeroType seroType2 = hlaType2.equivSafe(); + + boolean a1Match = + hlaType1.compareTo(hlaType1_First) == 0 || hlaType1.compareTo(hlaType2_First) == 0; + boolean a2Match = + hlaType2.compareTo(hlaType1_First) == 0 || hlaType2.compareTo(hlaType2_First) == 0; + + if (!a1Match || !a2Match) { + locusSet.clear(); + locusSet.add(seroType1); + locusSet.add(seroType2); + typesSet.clear(); + typesSet.add(hlaType1); + typesSet.add(hlaType2); + + ImmutableSortedSet prevSet = + ImmutableSortedSet.of(new TypePair(hlaType1_First, seroType1_First), + new TypePair(hlaType2_First, seroType2_First)); + + ImmutableSortedSet newSet = ImmutableSortedSet.of(new TypePair(hlaType1, seroType1), + new TypePair(hlaType2, seroType2)); + + + return Pair.of(prevSet, newSet); + } + + return null; + } + + private Region getSpacer() { + Region spacer = new Region(); + HBox.setHgrow(spacer, Priority.ALWAYS); + return spacer; + } + + private boolean isAnyPartCWD(String allele) { + HLAType alleleType = HLAType.valueOf(allele); + Status status1 = CommonWellDocumented.getStatus(alleleType); + + return status1 != Status.UNKNOWN; + } + + public static TextFlow getText(String allele) { + TextFlow flow = new TextFlow(); + if (allele.contains("-")) { + String[] a = allele.split("-"); + addTextNodes(flow, a[0], false); + flow.getChildren().add(new Text(" - ")); + addTextNodes(flow, a[1], true); + } else { + addTextNodes(flow, allele, true); + } + + return flow; + } + + static void addTextNodes(TextFlow flow, final String allele, boolean addSero) { + HLAType alleleType = HLAType.valueOf(allele); + HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); + Status status1 = CommonWellDocumented.getStatus(alleleType); + + flow.getChildren().add(new Text(alleleType.locus().name() + "*")); + + String specString = alleleType.specString(); + boolean match = allele.matches(ValidationModelBuilder.NOT_EXPRESSED) + || allele.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE); + + if (status1 != Status.UNKNOWN) { + + if (cwdType1.specString().length() < specString.length()) { + Text t1 = new Text(cwdType1.specString()); + t1.setStyle("-fx-font-weight:bold;"); + flow.getChildren().add(t1); + flow.getChildren().add(new Text(specString.substring(cwdType1.specString().length()))); + } else { + Text t1 = new Text(specString); + t1.setStyle("-fx-font-weight:bold;"); + flow.getChildren().add(t1); + } + + if (match) { + flow.getChildren().add(new Text("" + allele.charAt(allele.length() - 1))); + } + + } else { + flow.getChildren() + .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); + } + + if (addSero) { + flow.getChildren().add( + new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); + } + } + + public final static class AlleleStringConverter extends StringConverter> { + private final GUIRemapProcessor.PresentableAlleleChoices choices; + + private AlleleStringConverter(GUIRemapProcessor.PresentableAlleleChoices choices) { + this.choices = choices; + } + + @Override + public String toString(Supplier object) { + final String selectedData = choices.getData(object); + return selectedData == null ? "" : selectedData; + } + + @Override + public Supplier fromString(String string) { + return choices.getPresentation(string); + } + } + + public abstract static class PresentableDataChoices { + List choices; + Multimap secondChoices; + public BiMap dataMap; + + public PresentableDataChoices(List choices, Multimap secondChoices, + BiMap presentationToDataMap) { + this.choices = choices; + this.secondChoices = secondChoices; + this.dataMap = presentationToDataMap; + } + + public List getAllChoices() { + return choices; + } + + public Multimap getAllSecondChoices() { + return secondChoices; + } + + public Collection getSecondChoices(T firstChoice) { + return secondChoices.get(firstChoice); + } + + public abstract List getMatchingChoices(String userInput); + + public R getData(T presentable) { + return dataMap.get(presentable); + } + + public T getPresentation(R data) { + return dataMap.inverse().get(data); + } + + } + + public static class PresentableAlleleChoices + extends PresentableDataChoices, String> { + + public static PresentableAlleleChoices create(HLALocus locus, + ValidationModelBuilder.AllelePairings allelePairings) { + + List> userChoices = new ArrayList<>(); + ListMultimap, Supplier> secondChoices = + SortedSetMultimapBuilder.hashKeys().arrayListValues().build(); + BiMap, String> presentationToDataMap = HashBiMap.create(); + + List alleleKeys = new ArrayList<>(allelePairings.getAlleleKeys()); + sortAlleleStrings(alleleKeys); + + LinkedListMultimap choiceList = + condenseIntoGroups(allelePairings, alleleKeys, true); + + for (String allele : choiceList.keySet()) { + Supplier supp = () -> getText(allele); + + userChoices.add(supp); + presentationToDataMap.put(supp, allele); + } + + + for (Supplier choice : userChoices) { + String data = presentationToDataMap.get(choice); + if (data == null) { + continue; + } + String pairingAllele = data.contains("-") ? data.split("-")[0] : data; + + List pairings = new ArrayList<>(allelePairings.getValidPairings(pairingAllele)); + sortAlleleStrings(pairings); + + LinkedListMultimap secondChoicePairings = + condenseIntoGroups(allelePairings, pairings, false); + + for (String pairing : secondChoicePairings.keySet()) { + Supplier presentationView = presentationToDataMap.inverse().get(pairing); + if (presentationView == null) { + presentationView = () -> getText(pairing); + presentationToDataMap.put(presentationView, pairing); + } + secondChoices.put(choice, presentationView); + } + } + + Map alleleToGroupMap = new HashMap<>(); + choiceList.entries().stream().forEach(e -> { + alleleToGroupMap.put(e.getValue(), e.getKey()); + }); + + return new PresentableAlleleChoices(userChoices, secondChoices, presentationToDataMap, + allelePairings, alleleToGroupMap); + } + + private static LinkedListMultimap condenseIntoGroups( + ValidationModelBuilder.AllelePairings allelePairings, List alleleKeys, + boolean checkPairings) { + + List> subsets = new ArrayList<>(); + List subset = new ArrayList<>(); + + HLAType prev3FieldType = null; + + // all allele strings should be in the correct order now + // now let's condense into subsets of the same serotypes, with + // separate subsets for N/n and LSCAQ/lscaq alleles + for (String allele : alleleKeys) { + if (allele.matches(ValidationModelBuilder.NOT_EXPRESSED) + || allele.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE)) { + // make sure to add the currently-being-built subset first! + if (subset.size() > 0) { + subsets.add(subset); + subset = new ArrayList<>(); + } + // add null or lscaq alleles as single entries + subsets.add(Lists.newArrayList(allele)); + // clear out known three-field type + prev3FieldType = null; + continue; + } + + HLAType hType = HLAType.valueOf(allele); + if (hType.resolution() <= 2) { + // make sure to add the currently-being-built subset first! + if (subset.size() > 0) { + subsets.add(subset); + subset = new ArrayList<>(); + } + // add two-field alleles as single entries + subsets.add(Lists.newArrayList(allele)); + // clear out known three-field type + prev3FieldType = null; + continue; + } + + // we know resolution is >= 3 + + HLAType curr3FieldType = (hType.resolution() == 3) ? hType + : new HLAType(hType.locus(), hType.spec().get(0), hType.spec().get(1), + hType.spec().get(2)); + if (prev3FieldType != null && prev3FieldType.compareTo(curr3FieldType) != 0) { + // new three field type + subsets.add(subset); + subset = new ArrayList<>(); + } + // same or new three-field type, either way: + // update known three-field type, and + // add four-field type to subset + prev3FieldType = curr3FieldType; + subset.add(allele); + + } + if (subset.size() > 0) { + subsets.add(subset); + } + + LinkedListMultimap groupToAllelesMap = LinkedListMultimap.create(); + + // now we need to process the subset lists + // single element subsets can be added directly + // -- this preserves null/not-expressed subsets + // multiple element subsets need to be further + // separated into subsets: all alleles in a subset must + // map to the same serotype and the same second choice alleles + + for (List sub : subsets) { + if (sub.size() == 1) { + groupToAllelesMap.put(sub.get(0), sub.get(0)); + continue; + } + + List> subSubsets = new ArrayList<>(); + List subSubset = new ArrayList<>(); + + SeroType prevSero = null; + Set prevPairings = null; + + for (String subAllele : sub) { + HLAType type = HLAType.valueOf(subAllele); + SeroType newSero = type.equivSafe(); + HashSet newPairings = + checkPairings ? Sets.newHashSet(allelePairings.getValidPairings(subAllele)) + : new HashSet<>(); + if (prevSero == null) { + prevSero = newSero; + prevPairings = newPairings; + } else if (prevSero.compareTo(newSero) != 0) { + if (subSubset.size() > 0) { + subSubsets.add(subSubset); + subSubset = new ArrayList<>(); + } + prevSero = newSero; + prevPairings = newPairings; + } else if (!prevPairings.containsAll(newPairings) + || !newPairings.containsAll(prevPairings)) { + if (subSubset.size() > 0) { + subSubsets.add(subSubset); + subSubset = new ArrayList<>(); + } + prevSero = newSero; + prevPairings = newPairings; + } + subSubset.add(subAllele); + } + if (subSubset.size() > 0) { + subSubsets.add(subSubset); + subSubset = new ArrayList<>(); + } + + for (List subS : subSubsets) { + if (subS.size() == 1) { + groupToAllelesMap.put(subS.get(0), subS.get(0)); + } else { + String groupName = subS.get(0) + "-" + subS.get(subS.size() - 1); + for (String s : subS) { + groupToAllelesMap.put(groupName, s); + } + } + } + } + + return groupToAllelesMap; + } + + private static void sortAlleleStrings(List alleleKeys) { + alleleKeys.sort((s1, s2) -> { + boolean check1N = s1.matches(ValidationModelBuilder.NOT_EXPRESSED); + boolean check1C = s1.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE); + boolean check2N = s2.matches(ValidationModelBuilder.NOT_EXPRESSED); + boolean check2C = s2.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE); + boolean check1 = check1N || check1C; + boolean check2 = check2N || check2C; + // char s1C = s1.charAt(s1.length() - 1); + // char s2C = s2.charAt(s2.length() - 1); + String s1Hs = check1 ? s1.substring(0, s1.length() - 1) : s1; + String s2Hs = check2 ? s2.substring(0, s2.length() - 1) : s2; + + HLAType h1 = HLAType.valueOf(s1Hs); + HLAType h2 = HLAType.valueOf(s2Hs); + + int comp; + if ((comp = h1.compareTo(h2)) != 0) + return comp; + + if (check1 && !check2) { + // first element ends with special character, meaning second element should come first + return 1; + } else if (check2 && !check1) { + // second element ends with special character, meaning first element should come first + return -1; + } + + // both end with a special character + if (check1N && check2N) { + // both null and same HLAType - these are the same allele + return 0; + } else if (check1N && !check2N) { + // first element is null, second is lscaq, second comes first + return 1; + } else if (!check1N && check2N) { + // first element is lscaq, second is null, first comes first + return -1; + } + + + // this block could probably be condensed based on knowing null status from previous checks, + // but it's easier to just duplicate the logic for now... + + // both end with a special character + if (check1C && check2C) { + // both null and same HLAType - these are the same allele + return 0; + } else if (check1C && !check2C) { + // first element is null, second is lscaq, second comes first + return 1; + } else if (!check1C && check2C) { + // first element is lscaq, second is null, first comes first + return -1; + } + + // TODO dunno what's going on here... probably should do something special? + return 0; + }); + } + + private final ValidationModelBuilder.AllelePairings allelePairs; + + Map alleleToGroupKeyMap; + + public Supplier getChoiceForAllele(String allele) { + return getPresentation(alleleToGroupKeyMap.get(allele)); + } + + private PresentableAlleleChoices(List> choices, + Multimap, Supplier> secondChoices, + BiMap, String> presentationToDataMap, + ValidationModelBuilder.AllelePairings allelePairs, Map alleleToGroupMap) { + super(choices, secondChoices, presentationToDataMap); + this.allelePairs = allelePairs; + this.alleleToGroupKeyMap = alleleToGroupMap; + } + + @Override + public List> getMatchingChoices(String userInput) { + return allelePairs.getMatchingAlleles(userInput).stream().map(s -> dataMap.inverse().get(s)) + .filter(Predicates.notNull()).collect(Collectors.toList()); + } + + } + + static class SimpleTableObjectListCell extends ListCell> { + + // private Function, Supplier> tooltipProvider; + private Function, String> tooltipProvider; + private Tooltip tooltip = new Tooltip(); + + public SimpleTableObjectListCell(Function, String> tooltipProvider) { + // Function, Supplier> tooltipProvider) { + this.tooltipProvider = tooltipProvider; + + // hack for adjusting tooltip delay / etc + // from https://stackoverflow.com/a/43291239/875496 + // TODO FIXME change when JavaFX9+ is available + try { + Class clazz = tooltip.getClass().getDeclaredClasses()[0]; + Constructor constructor = clazz.getDeclaredConstructor(Duration.class, Duration.class, + Duration.class, boolean.class); + constructor.setAccessible(true); + Object tooltipBehavior = constructor.newInstance(new Duration(50), // open + new Duration(500000), // visible + new Duration(100), // close + false); + Field fieldBehavior = tooltip.getClass().getDeclaredField("BEHAVIOR"); + fieldBehavior.setAccessible(true); + fieldBehavior.set(tooltip, tooltipBehavior); + } catch (Throwable t) { + t.printStackTrace(); + } + + tooltip.setWrapText(true); + tooltip.setMaxWidth(600); + + /* + * NB: TODO FIXME setting style here because I couldn't figure out how to locate it in an + * actual CSS style sheet -- 04-18-2024, b.cole + */ + tooltip.setStyle( + "-fx-background: rgba(230,230,230); -fx-text-fill: black; -fx-background-color: rgba(230,230,230,0.95); -fx-background-radius: 5px; -fx-background-insets: 0; -fx-padding: 0.667em 0.75em 0.667em 0.75em; -fx-effect: dropshadow( three-pass-box , rgba(0,0,0,0.5) , 10, 0.0 , 0 , 3 ); -fx-font-size: 0.95em;"); + } + + @Override + public void updateItem(Supplier item, boolean empty) { + try { + super.updateItem(item, empty); + if (item != null && !empty) { + setGraphic(item.get()); + + String tf = tooltipProvider.apply(item); + // Supplier tf = tooltipProvider.apply(item); + if (tf == null || tf.length() < 150) { + // TODO don't show tooltips if item isn't too long! + setTooltip(null); + } else { + // System.out.println("tool:: " + tf); + tooltip.setText(tf); + // final TextFlow value = tf.get(); + // value.setMaxWidth(tooltip.getMaxWidth()); + // tooltip.setGraphic(value); + setTooltip(tooltip); + } + } else { + setGraphic(null); + setTooltip(null); + } + } catch (Throwable t) { + t.printStackTrace(); + } + } + + } + +} diff --git a/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java b/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java new file mode 100644 index 00000000..c3af1fc1 --- /dev/null +++ b/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java @@ -0,0 +1,14 @@ +package org.pankratzlab.unet.model.remap; + +import java.util.Set; +import org.apache.commons.lang3.tuple.Pair; +import org.pankratzlab.unet.deprecated.hla.HLALocus; +import org.pankratzlab.unet.model.ValidationModelBuilder; +import org.pankratzlab.unet.model.ValidationModelBuilder.TypePair; + +public interface RemapProcessor { + + public Pair, Set> processRemapping(HLALocus locus, + ValidationModelBuilder builder) throws CancellationException; + +} \ No newline at end of file diff --git a/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java b/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java index 2dbe185d..9f0d5733 100644 --- a/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java @@ -26,7 +26,6 @@ import java.io.IOException; import java.util.Optional; import java.util.function.BiFunction; - import org.jsoup.Jsoup; import org.jsoup.nodes.Document; import org.jsoup.nodes.Element; @@ -123,18 +122,18 @@ private void buildModelFromHTML(ValidationModelBuilder builder, Document parsed, typeParser.apply(parsed, "C2").ifPresent(builder::c); typeParser.apply(parsed, "DR1").ifPresent(builder::drb); typeParser.apply(parsed, "DR2").ifPresent(builder::drb); - typeParser.apply(parsed, "DQB1").ifPresent(builder::dqb); - typeParser.apply(parsed, "DQB2").ifPresent(builder::dqb); - typeParser.apply(parsed, "DQA1").ifPresent(builder::dqa); - typeParser.apply(parsed, "DQA2").ifPresent(builder::dqa); + typeParser.apply(parsed, "DQB1").ifPresent(builder::dqbSerotype); + typeParser.apply(parsed, "DQB2").ifPresent(builder::dqbSerotype); + typeParser.apply(parsed, "DQA1").ifPresent(builder::dqaSerotype); + typeParser.apply(parsed, "DQA2").ifPresent(builder::dqaSerotype); if (parsed.getElementsByAttributeValue(HTML_TYPE_ATTR, HTML_PREFIX + "DPA1").size() != 0) { - typeParser.apply(parsed, "DPA1").ifPresent(builder::dpa); + typeParser.apply(parsed, "DPA1").ifPresent(builder::dpaSerotype); } if (parsed.getElementsByAttributeValue(HTML_TYPE_ATTR, HTML_PREFIX + "DPA2").size() != 0) { - typeParser.apply(parsed, "DPA2").ifPresent(builder::dpa); + typeParser.apply(parsed, "DPA2").ifPresent(builder::dpaSerotype); } - typeParser.apply(parsed, "DPB1").ifPresent(builder::dpb); - typeParser.apply(parsed, "DPB2").ifPresent(builder::dpb); + typeParser.apply(parsed, "DPB1").ifPresent(builder::dpbSerotype); + typeParser.apply(parsed, "DPB2").ifPresent(builder::dpbSerotype); typeParser.apply(parsed, "BW4").ifPresent(s -> builder.bw4(decodeHTMLBoolean(s))); typeParser.apply(parsed, "BW6").ifPresent(s -> builder.bw6(decodeHTMLBoolean(s))); diff --git a/src/main/java/org/pankratzlab/unet/parser/util/PdfSureTyperParser.java b/src/main/java/org/pankratzlab/unet/parser/util/PdfSureTyperParser.java index 1bd42760..6f78cce0 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/PdfSureTyperParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/PdfSureTyperParser.java @@ -28,14 +28,12 @@ import java.util.Set; import java.util.StringJoiner; import java.util.function.BiConsumer; - import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.NullType; import org.pankratzlab.unet.hapstats.HaplotypeUtils; import org.pankratzlab.unet.model.Strand; import org.pankratzlab.unet.model.ValidationModelBuilder; - import com.google.common.collect.ArrayListMultimap; import com.google.common.collect.ImmutableMap; import com.google.common.collect.ImmutableMap.Builder; @@ -372,8 +370,8 @@ private static void init() { setterBuilder.put(HLA_B, new TypeSetter("B", ValidationModelBuilder::b)); setterBuilder.put(HLA_C, new TypeSetter("Cw", ValidationModelBuilder::c)); setterBuilder.put(HLA_DRB1, new TypeSetter("DR", ValidationModelBuilder::drb)); - setterBuilder.put(HLA_DQA1, new TypeSetter("DQA1*", ValidationModelBuilder::dqa)); - setterBuilder.put(HLA_DQB1, new TypeSetter("DQ", ValidationModelBuilder::dqb)); + setterBuilder.put(HLA_DQA1, new TypeSetter("DQA1*", ValidationModelBuilder::dqaSerotype)); + setterBuilder.put(HLA_DQB1, new TypeSetter("DQ", ValidationModelBuilder::dqbSerotype)); setterBuilder.put(HLA_DRB3, new TypeSetter("DRB3*", ValidationModelBuilder::dr52)); setterBuilder.put(HLA_DRB4, new TypeSetter("DRB4*", ValidationModelBuilder::dr53)); @@ -384,9 +382,9 @@ private static void init() { // DPA1 is present in the typing data but we do not currently track it in the validation model // (not entered in DonorNet) - setterBuilder.put(HLA_DPA1, new TypeSetter("DPA1*", ValidationModelBuilder::dpa)); + setterBuilder.put(HLA_DPA1, new TypeSetter("DPA1*", ValidationModelBuilder::dpaSerotype)); - setterBuilder.put(HLA_DPB1, new TypeSetter("DPB1*", ValidationModelBuilder::dpb)); + setterBuilder.put(HLA_DPB1, new TypeSetter("DPB1*", ValidationModelBuilder::dpbSerotype)); // Boolean values appear as literal values, indicating true, and are simply absent if false setterBuilder.put(BW, new TypeSetter("", PdfSureTyperParser::decodeBw)); diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index 0881df7a..4691fb5c 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -66,18 +66,18 @@ public final class SerotypeEquivalence { // System.out.println(h.toString() + "\t" + h.equivSafe()); // } - for (HLAType h : manualEquivalencies.keySet()) { - SeroType newS = careDxEquivalencies.get(h); - SeroType oldS = manualEquivalencies.get(h); - SeroType autoS = h.equivSafe(); - SeroType autoLS = h.lowResEquiv(); - if (newS == null) { - System.out.println(h + "\t" + oldS + "\t" + autoLS + "\t" + autoS); - } else if (oldS.compareTo(newS) != 0) { - System.out.println( - "----------- " + h + ": was " + oldS + " || now is " + newS + " (auto: " + autoS + ")"); - } - } + // for (HLAType h : manualEquivalencies.keySet()) { + // SeroType newS = careDxEquivalencies.get(h); + // SeroType oldS = manualEquivalencies.get(h); + // SeroType autoS = h.equivSafe(); + // SeroType autoLS = h.lowResEquiv(); + // if (newS == null) { + // System.out.println(h + "\t" + oldS + "\t" + autoLS + "\t" + autoS); + // } else if (oldS.compareTo(newS) != 0) { + // System.out.println( + // "----------- " + h + ": was " + oldS + " || now is " + newS + " (auto: " + autoS + ")"); + // } + // } } @@ -178,9 +178,6 @@ private static ImmutableMap buildManualOverrideLookup() { // put method for creating the reference table used in the get method. private static void put(Builder builder, String serotypeSpec, HLALocus locus, String... hlaSpecs) { - if (serotypeSpec.contains("(")) { - System.out.println(); - } SeroType s = new SeroType(locus.sero(), serotypeSpec); // create a one to one table for mapping alleles to serotype for (String allele : hlaSpecs) { diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlDonorNetParser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlDonorNetParser.java index a8b5e966..ecd2d7b3 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlDonorNetParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlDonorNetParser.java @@ -26,7 +26,6 @@ import java.util.Map; import java.util.Objects; import java.util.Optional; - import org.jsoup.Jsoup; import org.jsoup.nodes.Document; import org.jsoup.nodes.Element; @@ -35,7 +34,6 @@ import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; import org.pankratzlab.unet.parser.XmlDonorParser; - import com.google.common.collect.ImmutableMap; import com.google.common.collect.ImmutableMap.Builder; import com.google.common.collect.ImmutableSet; @@ -86,14 +84,14 @@ public static void buildModelFromXML(ValidationModelBuilder builder, Document do getXMLTagVal(donorRoot, "c2").ifPresent(builder::c); getXMLTagVal(donorRoot, "dr1").ifPresent(s -> builder.drb(decodeValue(drbMap, s))); getXMLTagVal(donorRoot, "dr2").ifPresent(s -> builder.drb(decodeValue(drbMap, s))); - getXMLTagVal(donorRoot, "dq1").ifPresent(s -> builder.dqb(decodeValue(dqbMap, s))); - getXMLTagVal(donorRoot, "dq2").ifPresent(s -> builder.dqb(decodeValue(dqbMap, s))); - getXMLTagVal(donorRoot, "dqa1").ifPresent(s -> builder.dqa(decodeValue(dqaMap, s))); - getXMLTagVal(donorRoot, "dqa2").ifPresent(s -> builder.dqa(decodeValue(dqaMap, s))); - getXMLTagVal(donorRoot, "dpa1").ifPresent(s -> builder.dpa(decodeValue(dpaMap, s))); - getXMLTagVal(donorRoot, "dpa2").ifPresent(s -> builder.dpa(decodeValue(dpaMap, s))); - getXMLTagVal(donorRoot, "dp1").ifPresent(s -> builder.dpb(decodeValue(dpbMap, s))); - getXMLTagVal(donorRoot, "dp2").ifPresent(s -> builder.dpb(decodeValue(dpbMap, s))); + getXMLTagVal(donorRoot, "dq1").ifPresent(s -> builder.dqbSerotype(decodeValue(dqbMap, s))); + getXMLTagVal(donorRoot, "dq2").ifPresent(s -> builder.dqbSerotype(decodeValue(dqbMap, s))); + getXMLTagVal(donorRoot, "dqa1").ifPresent(s -> builder.dqaSerotype(decodeValue(dqaMap, s))); + getXMLTagVal(donorRoot, "dqa2").ifPresent(s -> builder.dqaSerotype(decodeValue(dqaMap, s))); + getXMLTagVal(donorRoot, "dpa1").ifPresent(s -> builder.dpaSerotype(decodeValue(dpaMap, s))); + getXMLTagVal(donorRoot, "dpa2").ifPresent(s -> builder.dpaSerotype(decodeValue(dpaMap, s))); + getXMLTagVal(donorRoot, "dp1").ifPresent(s -> builder.dpbSerotype(decodeValue(dpbMap, s))); + getXMLTagVal(donorRoot, "dp2").ifPresent(s -> builder.dpbSerotype(decodeValue(dpbMap, s))); getXMLTagVal(donorRoot, "bw4").ifPresent(s -> builder.bw4(decodeXMLBoolean(s))); getXMLTagVal(donorRoot, "bw6").ifPresent(s -> builder.bw6(decodeXMLBoolean(s))); diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java index cbbbea14..1168d35b 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java @@ -120,12 +120,12 @@ private static void init() { setterBuilder.put(A_HEADER, ValidationModelBuilder::a); setterBuilder.put(B_HEADER, ValidationModelBuilder::b); setterBuilder.put(C_HEADER, ValidationModelBuilder::c); - setterBuilder.put(DQB_HEADER, ValidationModelBuilder::dqb); + setterBuilder.put(DQB_HEADER, ValidationModelBuilder::dqbSerotype); // Reported as allele types - setterBuilder.put(DPB_HEADER, ValidationModelBuilder::dpb); - setterBuilder.put(DQA_HEADER, ValidationModelBuilder::dqa); - setterBuilder.put(DPA_HEADER, ValidationModelBuilder::dpa); + setterBuilder.put(DPB_HEADER, ValidationModelBuilder::dpbSerotype); + setterBuilder.put(DQA_HEADER, ValidationModelBuilder::dqaSerotype); + setterBuilder.put(DPA_HEADER, ValidationModelBuilder::dpaSerotype); // DR52/53/54 appears as a serological combination setterBuilder.put(DRB_HEADER, ValidationModelBuilder::drb); @@ -146,7 +146,7 @@ private static void init() { // Reported as allele types // DPB is already being tracked as HLATypes - // setterBuilderTypes.put(DPB_HEADER, ValidationModelBuilder::dpbType); + setterBuilderTypes.put(DPB_HEADER, ValidationModelBuilder::dpb); setterBuilderTypes.put(DQA_HEADER, ValidationModelBuilder::dqaType); setterBuilderTypes.put(DPA_HEADER, ValidationModelBuilder::dpaType); @@ -169,7 +169,7 @@ private static void init() { // Reported as allele types // DPB is already being tracked as HLATypes - // setterBuilderTypes.put(DPB_HEADER, ValidationModelBuilder::dpbType); + setterBuilderTypesNonCWD.put(DPB_HEADER, ValidationModelBuilder::dpbNonCIWD); setterBuilderTypesNonCWD.put(DQA_HEADER, ValidationModelBuilder::dqaTypeNonCWD); setterBuilderTypesNonCWD.put(DPA_HEADER, ValidationModelBuilder::dpaTypeNonCWD); @@ -366,6 +366,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo if (hlaLocus == null) { hlaLocus = locusType; } else if (hlaLocus.compareTo(locusType) != 0) { + // TODO FIXME do something other than print to system out System.out .println("Parsed different locus (prev / new): " + hlaLocus + " / " + locusType); } @@ -497,6 +498,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo // record alleles for reassignment if necessary if (possibleAlleleRecordingMap.containsKey(locus)) { if (hlaLocus == null) { + // TODO FIXME do something other than print to system out System.out.println("Couldn't set alleles - no locus parsed from " + locus); } else { possibleAlleleRecordingMap.get(locus).accept(builder, hlaLocus, allPossibleAllelePairs); @@ -985,16 +987,21 @@ private static String getAlleleLookup(ResultCombination combination) { private static String getAlleleSpec(ResultCombination combination) { // Standard operating procedure is to just report the first field of the allele HLAType hlaType = combination.getAlleleCombination(); - StringJoiner sj = new StringJoiner(":"); - sj.add(String.valueOf(hlaType.spec().get(0))); - if (Objects.equals(HLALocus.DPA1, hlaType.locus()) - || Objects.equals(HLALocus.DPB1, hlaType.locus())) { - // DPA and DPB report two fields - sj.add(String.valueOf(hlaType.spec().get(1))); + if (hlaType.locus() == HLALocus.DPA1 || hlaType.locus() == HLALocus.DPB1) { + StringJoiner sj = new StringJoiner(":"); + sj.add(String.valueOf(hlaType.spec().get(0))); + + if (Objects.equals(HLALocus.DPA1, hlaType.locus()) + || Objects.equals(HLALocus.DPB1, hlaType.locus())) { + // DPA and DPB report two fields + sj.add(String.valueOf(hlaType.spec().get(1))); + } + + return sj.toString(); } - return sj.toString(); + return hlaType.equivSafe().specString(); } /** @@ -1013,6 +1020,7 @@ public ResultCombination(@Nonnull SeroType antigenCombination, Objects.requireNonNull(antigenCombination); Objects.requireNonNull(alleleCombination); } catch (NullPointerException e) { + // TODO FIXME do something other than print to system out System.out.println(); } this.alleleCombination = alleleCombination; diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlSureTyperParser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlSureTyperParser.java index 3ff599d5..8dbee190 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlSureTyperParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlSureTyperParser.java @@ -3,7 +3,6 @@ import java.util.Arrays; import java.util.HashMap; import java.util.Map; - import org.jsoup.nodes.Document; import org.jsoup.nodes.Element; import org.pankratzlab.unet.deprecated.hla.HLALocus; @@ -12,7 +11,6 @@ import org.pankratzlab.unet.model.Strand; import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; - import com.google.common.collect.ArrayListMultimap; import com.google.common.collect.Multimap; @@ -57,13 +55,13 @@ public static void buildModelFromXML(ValidationModelBuilder builder, Document do Arrays.stream(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, HLA_DRB1).text() .replaceAll("DR", "").split("\\s")).forEach(builder::drb); Arrays.stream(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, HLA_DQB1).text() - .replaceAll("DQ", "").split("\\s")).forEach(builder::dqb); + .replaceAll("DQ", "").split("\\s")).forEach(builder::dqbSerotype); Arrays.stream(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, HLA_DQA1).text() - .replaceAll("DQA1\\*", "").split("\\s")).forEach(builder::dqa); + .replaceAll("DQA1\\*", "").split("\\s")).forEach(builder::dqaSerotype); Arrays.stream(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, HLA_DPA1).text() - .replaceAll("DPA1\\*", "").split("\\s")).forEach(builder::dpa); + .replaceAll("DPA1\\*", "").split("\\s")).forEach(builder::dpaSerotype); Arrays.stream(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, HLA_DPB1).text() - .replaceAll("DPB1\\*", "").split("\\s")).forEach(builder::dpb); + .replaceAll("DPB1\\*", "").split("\\s")).forEach(builder::dpbSerotype); builder .bw4(labAssignmentSection.getElementsByAttributeValue(NAME_TAG, BW).text().contains("Bw4")); builder diff --git a/src/test/java/org/pankratzlab/unet/integration/PdfSureTyperParserTest.java b/src/test/java/org/pankratzlab/unet/integration/PdfSureTyperParserTest.java index 423a6aef..fbe4860f 100644 --- a/src/test/java/org/pankratzlab/unet/integration/PdfSureTyperParserTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/PdfSureTyperParserTest.java @@ -14,6 +14,7 @@ import org.junit.jupiter.params.provider.MethodSource; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; import org.pankratzlab.unet.model.ValidationModel; @@ -39,6 +40,7 @@ public class PdfSureTyperParserTest { @BeforeAll private static void init() { HaplotypeTestingUtils.initiateFreqTablesTesting(); + CommonWellDocumented.loadCIWD300(); } // create parameters to be used as CSV source for checking Donor ID parsing diff --git a/src/test/java/org/pankratzlab/unet/integration/XMLScore6ParserTest.java b/src/test/java/org/pankratzlab/unet/integration/XMLScore6ParserTest.java index 0fce6061..e0506f50 100644 --- a/src/test/java/org/pankratzlab/unet/integration/XMLScore6ParserTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/XMLScore6ParserTest.java @@ -15,6 +15,7 @@ import org.junit.jupiter.params.provider.MethodSource; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; import org.pankratzlab.unet.model.ValidationModel; @@ -37,6 +38,7 @@ public class XMLScore6ParserTest { @BeforeAll private static void init() { HaplotypeTestingUtils.initiateFreqTablesTesting(); + CommonWellDocumented.loadCIWD300(); } // create parameters to be used as CSV source for checking Donor ID parsing diff --git a/src/test/java/org/pankratzlab/unet/integration/XMLSureTyperParserTest.java b/src/test/java/org/pankratzlab/unet/integration/XMLSureTyperParserTest.java index 62ea9ecf..1cfdb542 100644 --- a/src/test/java/org/pankratzlab/unet/integration/XMLSureTyperParserTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/XMLSureTyperParserTest.java @@ -16,6 +16,7 @@ import org.junit.jupiter.params.provider.MethodSource; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; import org.pankratzlab.unet.hapstats.HaplotypeFrequencies; import org.pankratzlab.unet.hapstats.RaceGroup; import org.pankratzlab.unet.model.ValidationModel; @@ -34,6 +35,7 @@ public class XMLSureTyperParserTest { @BeforeAll private static void init() { HaplotypeTestingUtils.initiateFreqTablesTesting(); + CommonWellDocumented.loadCIWD300(); } // create parameters to be used as CSV source for checking Donor ID parsing From f1af65acc6872562fc245af7d22b4837cffe95fb Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 3 Jun 2024 14:16:43 -0500 Subject: [PATCH 07/23] Fix GUI padding --- .../unet/jfx/StyleableContingentChoiceDialog.java | 2 +- .../org/pankratzlab/unet/model/ValidationModelBuilder.java | 5 ++++- .../pankratzlab/unet/parser/util/SerotypeEquivalence.java | 5 ++++- 3 files changed, 9 insertions(+), 3 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index 530d82e9..f3841851 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -356,7 +356,7 @@ private void updateGrid(Node focusReq) { subGrid.getChildren().add(comboBox2); grid.add(subGrid, 0, 4); - grid.setPadding(new Insets(10, 0, 10, 25)); + grid.setPadding(new Insets(10, 25, 10, 25)); getDialogPane().setContent(grid); diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 5a79ce96..210aab0b 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -770,8 +770,11 @@ private void generateStrandOneHaplotypes( // sorts in descending order, notice h2's weight is found first Comparator c = ((h1, h2) -> { - return Double.compare(CommonWellDocumented.getEquivStatus(h2).getWeight(), + int d = Double.compare(CommonWellDocumented.getEquivStatus(h2).getWeight(), CommonWellDocumented.getEquivStatus(h1).getWeight()); + if (d != 0) + return d; + return h2.compareTo(h1); }); firstStrandTypes.sort(c); secondStrandTypes.sort(c); diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index 4691fb5c..cc1dfcf7 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -71,6 +71,9 @@ public final class SerotypeEquivalence { // SeroType oldS = manualEquivalencies.get(h); // SeroType autoS = h.equivSafe(); // SeroType autoLS = h.lowResEquiv(); + // if (h.locus() == HLALocus.B && h.spec().get(0) == 15 && h.spec().get(1) == 46) { + // System.out.println(h + "\t" + oldS + "\t" + autoLS + "\t" + autoS); + // } // if (newS == null) { // System.out.println(h + "\t" + oldS + "\t" + autoLS + "\t" + autoS); // } else if (oldS.compareTo(newS) != 0) { @@ -143,7 +146,7 @@ private static ImmutableMap buildManualOverrideLookup() { put(builder, "14", HLALocus.B, "14:03"); put(builder, "62", HLALocus.B, "15:01", "15:04", "15:05", "15:06", "15:07", "15:15", "15:24"); put(builder, "75", HLALocus.B, "15:02", "15:08"); - put(builder, "72", HLALocus.B, "15:03", "15:46"); + put(builder, "72", HLALocus.B, "15:46", "15:03"); put(builder, "70", HLALocus.B, "15:09"); put(builder, "71", HLALocus.B, "15:10", "15:18"); put(builder, "76", HLALocus.B, "15:12", "15:14"); From 4e60ee787964d20c4a1c400c904cdc9dab039acf Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Wed, 5 Jun 2024 14:13:40 -0500 Subject: [PATCH 08/23] Fix bugs in remappings; don't clear data sets, but return remapped value --- .../unet/model/ValidationModelBuilder.java | 80 +++++++++++++++++-- .../unet/model/remap/GUIRemapProcessor.java | 12 +-- 2 files changed, 79 insertions(+), 13 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 210aab0b..79f44226 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -566,6 +566,56 @@ public ValidationResult validate() { return ensureValidity(); } + private boolean test(Set set) { + return set == null || set.isEmpty(); + } + + private boolean test1(Set set) { + return set == null || set.isEmpty(); + } + + private Set getFinalTypes(HLALocus locus) { + Set returnTypes; + switch (locus) { + case A: + returnTypes = test(aLocusFirst) ? aLocusCWD : aLocusFirst; + break; + case B: + returnTypes = test(bLocusFirst) ? bLocusCWD : bLocusFirst; + break; + case C: + returnTypes = test(cLocusFirst) ? cLocusCWD : cLocusFirst; + break; + case DRB1: + case DRB3: + case DRB4: + case DRB5: + returnTypes = test(drbLocusNonCWD) ? drbLocus : drbLocusNonCWD; + break; + case DQA1: + returnTypes = test(dqaLocusNonCWD) ? dqaLocus : dqaLocusNonCWD; + break; + case DQB1: + returnTypes = test(dqbLocusNonCWD) ? dqbLocus : dqbLocusNonCWD; + break; + case DPA1: + returnTypes = test(dpaLocusNonCWD) ? dpaLocus : dpaLocusNonCWD; + break; + case DPB1: + case MICA: + default: + return null; + } + returnTypes = new LinkedHashSet<>(returnTypes); + if (remapping.containsKey(locus)) { + List types = remapping.get(locus).getRight().stream().map(TypePair::getSeroType) + .collect(Collectors.toList()); + returnTypes.clear(); + returnTypes.addAll(types); + } + return returnTypes; + } + /** @return The immutable {@link ValidationModel} based on the current builder state. */ public ValidationModel build() { Multimap bcCwdHaplotypes = buildBCHaplotypes(bHaplotypes, cHaplotypes); @@ -575,9 +625,11 @@ public ValidationModel build() { frequencyTable.clear(); - ValidationModel validationModel = new ValidationModel(donorId, source, sourceType, aLocusCWD, - bLocusCWD, cLocusCWD, drbLocus, dqbLocus, dqaLocus, dpaLocus, getFinalDPBTypes(), bw4, bw6, - dr51Locus, dr52Locus, dr53Locus, bcCwdHaplotypes, drDqDR345Haplotypes, remapping); + ValidationModel validationModel = new ValidationModel(donorId, source, sourceType, + getFinalTypes(HLALocus.A), getFinalTypes(HLALocus.B), getFinalTypes(HLALocus.C), + getFinalTypes(HLALocus.DRB1), getFinalTypes(HLALocus.DQB1), getFinalTypes(HLALocus.DQA1), + getFinalTypes(HLALocus.DPA1), getFinalDPBTypes(), bw4, bw6, dr51Locus, dr52Locus, dr53Locus, + bcCwdHaplotypes, drDqDR345Haplotypes, remapping); return validationModel; } @@ -585,10 +637,24 @@ bLocusCWD, cLocusCWD, drbLocus, dqbLocus, dqaLocus, dpaLocus, getFinalDPBTypes() // not be entered into UNOS private Set getFinalDPBTypes() { Set dpbTypes = new HashSet<>(); - Set dpbSource = dpbLocusTypes; - if (dpbSource == null || dpbSource.isEmpty()) { - dpbSource = dpbLocus.stream().map(s -> new HLAType(HLALocus.DPB1, s.spec())) - .collect(ImmutableSet.toImmutableSet()); + Set dpbSource = new LinkedHashSet<>(); + + Set returnTypes = new LinkedHashSet<>(); + if (remapping.containsKey(HLALocus.DPB1)) { + List types = remapping.get(HLALocus.DPB1).getRight().stream() + .map(TypePair::getHlaType).collect(Collectors.toList()); + returnTypes.clear(); + returnTypes.addAll(types); + } + if (!returnTypes.isEmpty()) { + dpbSource.addAll(returnTypes); + } else { + dpbSource = test1(dpbLocusTypesNonCWD) ? dpbLocusTypes : dpbLocusTypesNonCWD; + Set dpbBackup = test1(dpbLocusNonCWD) ? dpbLocus : trim(dpbLocusNonCWD); + if (dpbSource == null || dpbSource.isEmpty()) { + dpbSource = dpbBackup.stream().map(s -> new HLAType(HLALocus.DPB1, s.spec())) + .collect(ImmutableSet.toImmutableSet()); + } } for (HLAType dpbType1 : dpbSource) { String dpbType = dpbType1.specString(); diff --git a/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java index a79b78c8..467ee52e 100644 --- a/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java +++ b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java @@ -202,12 +202,12 @@ public Pair, Set> processRemapping(HLALocus locus, hlaType2.compareTo(hlaType1_First) == 0 || hlaType2.compareTo(hlaType2_First) == 0; if (!a1Match || !a2Match) { - locusSet.clear(); - locusSet.add(seroType1); - locusSet.add(seroType2); - typesSet.clear(); - typesSet.add(hlaType1); - typesSet.add(hlaType2); + // locusSet.clear(); + // locusSet.add(seroType1); + // locusSet.add(seroType2); + // typesSet.clear(); + // typesSet.add(hlaType1); + // typesSet.add(hlaType2); ImmutableSortedSet prevSet = ImmutableSortedSet.of(new TypePair(hlaType1_First, seroType1_First), From c5a9ba4d0054ba3e3e1a784c7b5fa687b81cfa08 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Wed, 5 Jun 2024 14:29:51 -0500 Subject: [PATCH 09/23] Fix allele-to-serotype parsing --- .../deprecated/hla/AntigenDictionary.java | 35 ++++++++++--------- 1 file changed, 18 insertions(+), 17 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java index 2a28dcb1..0e8331d9 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java @@ -31,7 +31,6 @@ import java.nio.file.Files; import java.nio.file.Paths; import java.util.ArrayList; -import java.util.LinkedHashSet; import java.util.List; import java.util.Set; import java.util.concurrent.Callable; @@ -205,12 +204,13 @@ private static void parseDictionaries(Callable readerSupplier) { // Parse out the serological specificities for this mapping // Since the columns are ordered by specificity, we use the first column with valid entries - Set seroSpecs = new LinkedHashSet<>(); + // Set seroSpecs = new LinkedHashSet<>(); + List seroSpecs = new ArrayList<>(); for (int i = 2; i <= 5 && i < columns.length; i++) { String types = columns[i]; // Each HLA type may map to multiple serotypes for (String t : types.split(TYPE_DELIM)) { - if (!t.isEmpty()) { + if (!t.isEmpty() && !seroSpecs.contains(t)) { seroSpecs.add(t); } } @@ -236,25 +236,26 @@ private static void parseDictionaries(Callable readerSupplier) { for (int i = 0; i < specValues.length; i++) { specValues[i] = specValues[i].trim().replaceAll("[^0-9]", ""); spec.add(Integer.parseInt(specValues[i])); + } - HLAType hlaType = new HLAType(l, spec); + HLAType hlaType = new HLAType(l, spec); - SeroLocus sl = l.sero(); - for (String t : seroSpecs) { - // Convert unknown types to the first spec value - if (UNKNOWN_TYPE.equals(t)) { - t = specValues[0]; - } - SeroType seroType = new SeroType(sl, t); - hlaBuilder.put(hlaType, seroType); + SeroLocus sl = l.sero(); + for (String t : seroSpecs) { + // Convert unknown types to the first spec value + if (UNKNOWN_TYPE.equals(t)) { + t = specValues[0]; + } + SeroType seroType = new SeroType(sl, t); + hlaBuilder.put(hlaType, seroType); - // Only map from sero > hla if we have 2 or more specificities - if (spec.size() > 1) { - validHLATypes.add(hlaType); - seroBuilder.put(seroType, hlaType); - } + // Only map from sero > hla if we have 2 or more specificities + if (spec.size() > 1) { + validHLATypes.add(hlaType); + seroBuilder.put(seroType, hlaType); } } + // } } // Build the singleton map and write it to disk From d0473210bbbec05492d581a9e4f3aae27368f017 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Thu, 6 Jun 2024 11:25:00 -0500 Subject: [PATCH 10/23] Fix mouse behavior in StyleableContingentChoiceDialog Remove blank lines / unnecessary code from other files. --- .../jfx/StyleableContingentChoiceDialog.java | 27 +++++++++---------- .../unet/jfx/wizard/FileInputController.java | 2 -- .../wizard/ValidationResultsController.java | 2 -- .../unet/model/ValidationTable.java | 1 - 4 files changed, 13 insertions(+), 19 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java index f3841851..00611807 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java +++ b/src/main/java/org/pankratzlab/unet/jfx/StyleableContingentChoiceDialog.java @@ -122,7 +122,6 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, comboBox2.setDisable(true); comboBox1 = new ComboBox(); - // comboBox1.setEditable(true); comboBox1.setMinWidth(MIN_WIDTH); if (choices != null) { comboBox1.getItems().addAll(choices); @@ -146,18 +145,6 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, opt1Choice = new RadioButton(); opt2Choice = new RadioButton(); - opt1.graphic.setOnMouseClicked(opt1Choice.getOnMouseClicked()); - opt1.graphic.setOnMouseEntered(opt1Choice.getOnMouseEntered()); - opt1.graphic.setOnMouseExited(opt1Choice.getOnMouseExited()); - opt1.graphic.setOnMousePressed(opt1Choice.getOnMousePressed()); - opt1.graphic.setOnMouseReleased(opt1Choice.getOnMouseReleased()); - - opt2.graphic.setOnMouseClicked(opt2Choice.getOnMouseClicked()); - opt2.graphic.setOnMouseEntered(opt2Choice.getOnMouseEntered()); - opt2.graphic.setOnMouseExited(opt2Choice.getOnMouseExited()); - opt2.graphic.setOnMousePressed(opt2Choice.getOnMousePressed()); - opt2.graphic.setOnMouseReleased(opt2Choice.getOnMouseReleased()); - manualChoice = new RadioButton(); manualChoice.setGraphic(manualChoiceGraphic); @@ -170,6 +157,19 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, comboBox1.getSelectionModel().select(defaultChoice); } + // bind mouse behavior so the radio buttons fire events when the graphics are interacted with + opt1.graphic.setOnMouseClicked(event -> opt1Choice.fireEvent(event)); + opt1.graphic.setOnMouseEntered(event -> opt1Choice.fireEvent(event)); + opt1.graphic.setOnMouseExited(event -> opt1Choice.fireEvent(event)); + opt1.graphic.setOnMousePressed(event -> opt1Choice.fireEvent(event)); + opt1.graphic.setOnMouseReleased(event -> opt1Choice.fireEvent(event)); + + opt2.graphic.setOnMouseClicked(event -> opt2Choice.fireEvent(event)); + opt2.graphic.setOnMouseEntered(event -> opt2Choice.fireEvent(event)); + opt2.graphic.setOnMouseExited(event -> opt2Choice.fireEvent(event)); + opt2.graphic.setOnMousePressed(event -> opt2Choice.fireEvent(event)); + opt2.graphic.setOnMouseReleased(event -> opt2Choice.fireEvent(event)); + // these are basic bindings checkboxFilter1.disableProperty().bind(manualChoice.selectedProperty().not()); checkboxFilter2.disableProperty().bind(manualChoice.selectedProperty().not()); @@ -218,7 +218,6 @@ public StyleableContingentChoiceDialog(T defaultChoice, Collection choices, return data == ButtonData.OK_DONE ? getSelectedItem() : null; }); - } private ObservableList getFirstComboChoices(boolean filterActive, Collection choices) { diff --git a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java index cfd8f807..f5ab711f 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java +++ b/src/main/java/org/pankratzlab/unet/jfx/wizard/FileInputController.java @@ -171,8 +171,6 @@ private void selectDonorFile(ActionEvent event, DonorFileParser donorParser, alertInvalid(donorParser, selectedFile, validationResult); } - - // check for corrections if (builder.hasCorrections()) { diff --git a/src/main/java/org/pankratzlab/unet/jfx/wizard/ValidationResultsController.java b/src/main/java/org/pankratzlab/unet/jfx/wizard/ValidationResultsController.java index 4de60ea2..c21d2448 100644 --- a/src/main/java/org/pankratzlab/unet/jfx/wizard/ValidationResultsController.java +++ b/src/main/java/org/pankratzlab/unet/jfx/wizard/ValidationResultsController.java @@ -285,7 +285,6 @@ void initialize() { @Override protected void refreshTable(ValidationTable table) { // Can only finish the wizard if the validation is successful - rootPane.setInvalidBinding(table.isValidProperty().not()); resultsTable.setItems(table.getValidationRows()); table.isValidProperty().addListener(e -> updateDisplay(table.isValidProperty().get())); @@ -296,7 +295,6 @@ protected void refreshTable(ValidationTable table) { bcHaplotypeTable.setItems(table.getBCHaplotypeRows()); drdqHaplotypeTable.setItems(table.getDRDQHaplotypeRows()); - } /** Perform required actions when the page is being displayed */ diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationTable.java b/src/main/java/org/pankratzlab/unet/model/ValidationTable.java index bf592db9..12f5b644 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationTable.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationTable.java @@ -74,7 +74,6 @@ public ValidationTable() { auditLogLines = new ReadOnlyListWrapper<>(FXCollections.observableArrayList()); bcHaplotypeRows = new ReadOnlyListWrapper<>(FXCollections.observableArrayList()); drdqHaplotypeRows = new ReadOnlyListWrapper<>(FXCollections.observableArrayList()); - new ReadOnlyObjectWrapper<>(); // Each time either model changes we re-generate the rows firstModelWrapper.addListener((v, o, n) -> generateRows()); From d96d2bdf379da248ea4f1c0375b05c4123b4c406 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Thu, 6 Jun 2024 15:22:52 -0500 Subject: [PATCH 11/23] Don't continue showing dialogs if user presses cancel button --- .../org/pankratzlab/unet/model/ValidationModelBuilder.java | 3 +-- 1 file changed, 1 insertion(+), 2 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 79f44226..32d302ff 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -1052,8 +1052,7 @@ public ValidationResult processCorrections(RemapProcessor remapProcessor) { remapPair = remapProcessor.processRemapping(locus, this); } catch (CancellationException e) { cancelled = true; - } catch (Throwable t) { - t.printStackTrace(); + break; } if (remapPair != null) { From 3b49fa43b81e63a3c621fb23329b88a449cf2ab6 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Thu, 6 Jun 2024 15:23:12 -0500 Subject: [PATCH 12/23] Move Allele to TextFlow utility methods to new class --- .../CIWDAlleleStringPresentationUtils.java | 66 ++++++++++++++++++ .../unet/model/remap/GUIRemapProcessor.java | 69 +++---------------- 2 files changed, 75 insertions(+), 60 deletions(-) create mode 100644 src/main/java/org/pankratzlab/unet/model/remap/CIWDAlleleStringPresentationUtils.java diff --git a/src/main/java/org/pankratzlab/unet/model/remap/CIWDAlleleStringPresentationUtils.java b/src/main/java/org/pankratzlab/unet/model/remap/CIWDAlleleStringPresentationUtils.java new file mode 100644 index 00000000..04afe993 --- /dev/null +++ b/src/main/java/org/pankratzlab/unet/model/remap/CIWDAlleleStringPresentationUtils.java @@ -0,0 +1,66 @@ +package org.pankratzlab.unet.model.remap; + +import org.pankratzlab.unet.deprecated.hla.HLAType; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; +import org.pankratzlab.unet.hapstats.CommonWellDocumented.Status; +import org.pankratzlab.unet.model.ValidationModelBuilder; +import javafx.scene.text.Text; +import javafx.scene.text.TextFlow; + +public class CIWDAlleleStringPresentationUtils { + + + public static TextFlow getText(String allele) { + TextFlow flow = new TextFlow(); + if (allele.contains("-")) { + String[] a = allele.split("-"); + addTextNodes(flow, a[0], false); + flow.getChildren().add(new Text(" - ")); + addTextNodes(flow, a[1], true); + } else { + addTextNodes(flow, allele, true); + } + + return flow; + } + + static void addTextNodes(TextFlow flow, final String allele, boolean addSero) { + HLAType alleleType = HLAType.valueOf(allele); + HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); + Status status1 = CommonWellDocumented.getStatus(alleleType); + + flow.getChildren().add(new Text(alleleType.locus().name() + "*")); + + String specString = alleleType.specString(); + boolean match = allele.matches(ValidationModelBuilder.NOT_EXPRESSED) + || allele.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE); + + if (status1 != Status.UNKNOWN) { + + if (cwdType1.specString().length() < specString.length()) { + Text t1 = new Text(cwdType1.specString()); + t1.setStyle("-fx-font-weight:bold;"); + flow.getChildren().add(t1); + flow.getChildren().add(new Text(specString.substring(cwdType1.specString().length()))); + } else { + Text t1 = new Text(specString); + t1.setStyle("-fx-font-weight:bold;"); + flow.getChildren().add(t1); + } + + if (match) { + flow.getChildren().add(new Text("" + allele.charAt(allele.length() - 1))); + } + + } else { + flow.getChildren() + .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); + } + + if (addSero) { + flow.getChildren().add( + new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); + } + } + +} diff --git a/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java index 467ee52e..fa96a12b 100644 --- a/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java +++ b/src/main/java/org/pankratzlab/unet/model/remap/GUIRemapProcessor.java @@ -65,7 +65,7 @@ public Pair, Set> processRemapping(HLALocus locus, AllelePairings allelePairs = builder.getPossibleAllelePairsForLocus(locus); AllelePairings donorPairs = builder.getDonorAllelePairsForLocus(locus); - Set locusSet = builder.getCWDSeroTypesForLocus(locus); + // Set locusSet = builder.getCWDSeroTypesForLocus(locus); Set locusSetNonCWD = builder.getAllSeroTypesForLocus(locus); Set typesSet = builder.getCWDTypesForLocus(locus); Set typesSetNonCWD = builder.getAllTypesForLocus(locus); @@ -110,9 +110,11 @@ public Pair, Set> processRemapping(HLALocus locus, assignedPane.setAlignment(Pos.CENTER_LEFT); Label assignedHeader = new Label("Assigned allele pair: "); TextFlow assignedTextFlow = new TextFlow(); - addTextNodes(assignedTextFlow, hlaType1_First.toString(), true); + CIWDAlleleStringPresentationUtils.addTextNodes(assignedTextFlow, hlaType1_First.toString(), + true); assignedTextFlow.getChildren().add(new Text(" | ")); - addTextNodes(assignedTextFlow, hlaType2_First.toString(), true); + CIWDAlleleStringPresentationUtils.addTextNodes(assignedTextFlow, hlaType2_First.toString(), + true); Label assignedHeaderLbl = new Label("", assignedTextFlow); assignedHeaderLbl.setMaxWidth(Double.MAX_VALUE); assignedHeaderLbl.setMaxHeight(Double.MAX_VALUE); @@ -125,9 +127,9 @@ public Pair, Set> processRemapping(HLALocus locus, ciwdPane.setAlignment(Pos.CENTER_LEFT); Label ciwdHeader = new Label("Common / Well-Documented allele pair: "); TextFlow ciwdTextFlow = new TextFlow(); - addTextNodes(ciwdTextFlow, hlaType1_CIWD.toString(), true); + CIWDAlleleStringPresentationUtils.addTextNodes(ciwdTextFlow, hlaType1_CIWD.toString(), true); ciwdTextFlow.getChildren().add(new Text(" | ")); - addTextNodes(ciwdTextFlow, hlaType2_CIWD.toString(), true); + CIWDAlleleStringPresentationUtils.addTextNodes(ciwdTextFlow, hlaType2_CIWD.toString(), true); Label ciwdHeaderLbl = new Label("", ciwdTextFlow); ciwdHeaderLbl.setMaxWidth(Double.MAX_VALUE); ciwdHeaderLbl.setMaxHeight(Double.MAX_VALUE); @@ -236,59 +238,6 @@ private boolean isAnyPartCWD(String allele) { return status1 != Status.UNKNOWN; } - public static TextFlow getText(String allele) { - TextFlow flow = new TextFlow(); - if (allele.contains("-")) { - String[] a = allele.split("-"); - addTextNodes(flow, a[0], false); - flow.getChildren().add(new Text(" - ")); - addTextNodes(flow, a[1], true); - } else { - addTextNodes(flow, allele, true); - } - - return flow; - } - - static void addTextNodes(TextFlow flow, final String allele, boolean addSero) { - HLAType alleleType = HLAType.valueOf(allele); - HLAType cwdType1 = CommonWellDocumented.getCWDType(alleleType); - Status status1 = CommonWellDocumented.getStatus(alleleType); - - flow.getChildren().add(new Text(alleleType.locus().name() + "*")); - - String specString = alleleType.specString(); - boolean match = allele.matches(ValidationModelBuilder.NOT_EXPRESSED) - || allele.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE); - - if (status1 != Status.UNKNOWN) { - - if (cwdType1.specString().length() < specString.length()) { - Text t1 = new Text(cwdType1.specString()); - t1.setStyle("-fx-font-weight:bold;"); - flow.getChildren().add(t1); - flow.getChildren().add(new Text(specString.substring(cwdType1.specString().length()))); - } else { - Text t1 = new Text(specString); - t1.setStyle("-fx-font-weight:bold;"); - flow.getChildren().add(t1); - } - - if (match) { - flow.getChildren().add(new Text("" + allele.charAt(allele.length() - 1))); - } - - } else { - flow.getChildren() - .add(new Text(specString + (match ? ("" + allele.charAt(allele.length() - 1)) : ""))); - } - - if (addSero) { - flow.getChildren().add( - new Text(" (" + alleleType.locus().name() + alleleType.equivSafe().specString() + ")")); - } - } - public final static class AlleleStringConverter extends StringConverter> { private final GUIRemapProcessor.PresentableAlleleChoices choices; @@ -362,7 +311,7 @@ public static PresentableAlleleChoices create(HLALocus locus, condenseIntoGroups(allelePairings, alleleKeys, true); for (String allele : choiceList.keySet()) { - Supplier supp = () -> getText(allele); + Supplier supp = () -> CIWDAlleleStringPresentationUtils.getText(allele); userChoices.add(supp); presentationToDataMap.put(supp, allele); @@ -385,7 +334,7 @@ public static PresentableAlleleChoices create(HLALocus locus, for (String pairing : secondChoicePairings.keySet()) { Supplier presentationView = presentationToDataMap.inverse().get(pairing); if (presentationView == null) { - presentationView = () -> getText(pairing); + presentationView = () -> CIWDAlleleStringPresentationUtils.getText(pairing); presentationToDataMap.put(presentationView, pairing); } secondChoices.put(choice, presentationView); From 36595a57d15c6959ba2efc00eb3a35b4c8db4ea3 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Thu, 6 Jun 2024 22:45:18 -0500 Subject: [PATCH 13/23] Increment AntigenDictionary svUID to force reparsing --- .../org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java index 0e8331d9..8ef510b1 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java @@ -44,7 +44,7 @@ /** Persistent map of {@link HLAType}s to equivalent {@link SeroType}s. Use when converting. */ public final class AntigenDictionary implements Serializable { - private static final long serialVersionUID = 11L; + private static final long serialVersionUID = 12L; public static final String REL_DNA_SER_PROP = "rel.dna.ser.file"; From b905223b3ec601d7d7e4f1d10c7c01cab6574f7b Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Thu, 6 Jun 2024 22:46:00 -0500 Subject: [PATCH 14/23] Add new SourceType enum, add testing remapping processor --- .../unet/deprecated/hla/SourceType.java | 5 ++ .../unet/model/ValidationModel.java | 18 ++--- .../unet/model/ValidationModelBuilder.java | 10 ++- .../unet/parser/HtmlDonorParser.java | 3 +- .../unet/parser/PdfDonorParser.java | 4 +- .../unet/parser/XmlDonorParser.java | 7 +- .../unet/integration/IntegrationTest.java | 35 ++++++++-- .../unet/integration/XMLRemapProcessor.java | 68 +++++++++++++++++++ 8 files changed, 127 insertions(+), 23 deletions(-) create mode 100644 src/main/java/org/pankratzlab/unet/deprecated/hla/SourceType.java create mode 100644 src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/SourceType.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/SourceType.java new file mode 100644 index 00000000..d448f573 --- /dev/null +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/SourceType.java @@ -0,0 +1,5 @@ +package org.pankratzlab.unet.deprecated.hla; + +public enum SourceType { + Score6, SureTyper, DonorNet; +} diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModel.java b/src/main/java/org/pankratzlab/unet/model/ValidationModel.java index 2be44ff8..a297db34 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModel.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModel.java @@ -32,6 +32,7 @@ import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.HLAType; import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.deprecated.hla.SourceType; import org.pankratzlab.unet.hapstats.Haplotype; import org.pankratzlab.unet.hapstats.RaceGroup; import org.pankratzlab.unet.model.ValidationModelBuilder.TypePair; @@ -50,7 +51,7 @@ public class ValidationModel { private final String donorId; private final String source; - private final String sourceType; + private final SourceType sourceType; private final ImmutableSortedSet aLocus; private final ImmutableSortedSet bLocus; private final ImmutableSortedSet cLocus; @@ -68,11 +69,12 @@ public class ValidationModel { private final ImmutableMultimap drdqHaplotypes; private final ImmutableMap, Set>> remapping; - public ValidationModel(String donorId, String source, String sourceType, Collection a, - Collection b, Collection c, Collection drb, - Collection dqb, Collection dqa, Collection dpa, - Collection dpb, boolean bw4, boolean bw6, List dr51, List dr52, - List dr53, Multimap bcCwdHaplotypes, + public ValidationModel(String donorId, String source, SourceType sourceType, + Collection a, Collection b, Collection c, + Collection drb, Collection dqb, Collection dqa, + Collection dpa, Collection dpb, boolean bw4, boolean bw6, + List dr51, List dr52, List dr53, + Multimap bcCwdHaplotypes, Multimap drdqCwdHaplotypes, Map, Set>> remapping) { this.donorId = donorId; @@ -111,7 +113,7 @@ public String getSource() { return source; } - public String getSourceType() { + public SourceType getSourceType() { return sourceType; } @@ -357,7 +359,7 @@ public String toString() { StringJoiner sj = new StringJoiner("\n"); sj.add(getDonorId()); sj.add(getSource()); - sj.add(getSourceType()); + sj.add(getSourceType().name()); addPair(sj, getA1(), getA2()); addPair(sj, getB1(), getB2()); addPair(sj, getC1(), getC2()); diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index 32d302ff..e2d7f281 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -48,6 +48,7 @@ import org.pankratzlab.unet.deprecated.hla.NullType; import org.pankratzlab.unet.deprecated.hla.SeroLocus; import org.pankratzlab.unet.deprecated.hla.SeroType; +import org.pankratzlab.unet.deprecated.hla.SourceType; import org.pankratzlab.unet.hapstats.AlleleGroups; import org.pankratzlab.unet.hapstats.CommonWellDocumented; import org.pankratzlab.unet.hapstats.CommonWellDocumented.Status; @@ -100,7 +101,7 @@ public class ValidationModelBuilder { private String donorId; private String source; - private String sourceType; + private SourceType sourceType; // TODO replace per-locus data structures with maps from [Sero|HLA]Locus to data structure // (or tables as appropriate) @@ -174,11 +175,16 @@ public ValidationModelBuilder source(String source) { } /** @param source Name for the source of this model */ - public ValidationModelBuilder sourceType(String sourceType) { + public ValidationModelBuilder sourceType(SourceType sourceType) { this.sourceType = sourceType; return this; } + /** @param source Name for the source of this model */ + public SourceType getSourceType() { + return sourceType; + } + public ValidationModelBuilder a(String aSeroType) { if (test1(aSeroType)) { return null; diff --git a/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java b/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java index 9f0d5733..de8a2388 100644 --- a/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/HtmlDonorParser.java @@ -30,6 +30,7 @@ import org.jsoup.nodes.Document; import org.jsoup.nodes.Element; import org.jsoup.select.Elements; +import org.pankratzlab.unet.deprecated.hla.SourceType; import org.pankratzlab.unet.jfx.DonorNetUtils; import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; @@ -94,7 +95,7 @@ protected void doParse(ValidationModelBuilder builder, File file) { // Test for saved or unsaved HTML state // No selected elements means this has been saved previously Elements selectedElements = parsed.getElementsByAttribute(SELECTED_ATTRIBUTE); - builder.sourceType("DonorNet"); + builder.sourceType(SourceType.DonorNet); if (selectedElements.isEmpty()) { buildModelFromHTML(builder, parsed, this::getSavedHTMLType); diff --git a/src/main/java/org/pankratzlab/unet/parser/PdfDonorParser.java b/src/main/java/org/pankratzlab/unet/parser/PdfDonorParser.java index 0ac2e476..148f5609 100644 --- a/src/main/java/org/pankratzlab/unet/parser/PdfDonorParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/PdfDonorParser.java @@ -23,10 +23,10 @@ import java.io.File; import java.io.IOException; - import org.apache.pdfbox.pdmodel.PDDocument; import org.apache.pdfbox.pdmodel.encryption.InvalidPasswordException; import org.apache.pdfbox.text.PDFTextStripper; +import org.pankratzlab.unet.deprecated.hla.SourceType; import org.pankratzlab.unet.model.ValidationModelBuilder; import org.pankratzlab.unet.parser.util.PdfSureTyperParser; @@ -81,7 +81,7 @@ protected void doParse(ValidationModelBuilder builder, File file) { String[] pdfLines = pdfText.split(System.getProperty("line.separator")); // Pass the text to the appropriate parser - builder.sourceType("SureTyper"); + builder.sourceType(SourceType.SureTyper); PdfSureTyperParser.parseTypes(builder, pdfLines); // FIXME currently not well supported // else if (pdfText.contains(QTYPER)) { diff --git a/src/main/java/org/pankratzlab/unet/parser/XmlDonorParser.java b/src/main/java/org/pankratzlab/unet/parser/XmlDonorParser.java index 3c141c0e..895f9c01 100644 --- a/src/main/java/org/pankratzlab/unet/parser/XmlDonorParser.java +++ b/src/main/java/org/pankratzlab/unet/parser/XmlDonorParser.java @@ -27,6 +27,7 @@ import org.apache.commons.io.FilenameUtils; import org.jsoup.Jsoup; import org.jsoup.nodes.Document; +import org.pankratzlab.unet.deprecated.hla.SourceType; import org.pankratzlab.unet.model.ValidationModelBuilder; import org.pankratzlab.unet.parser.util.XmlDonorNetParser; import org.pankratzlab.unet.parser.util.XmlScore6Parser; @@ -89,13 +90,13 @@ protected void doParse(ValidationModelBuilder builder, File file) { // Based on XML contents, pass to specific XML parser if (XmlDonorNetParser.ROOT_ELEMENT.equals(rootElement)) { - builder.sourceType("DonorNet"); + builder.sourceType(SourceType.DonorNet); XmlDonorNetParser.buildModelFromXML(builder, parsed); } else if (XmlScore6Parser.ROOT_ELEMENT.equals(rootElement)) { - builder.sourceType("Score6"); + builder.sourceType(SourceType.Score6); XmlScore6Parser.buildModelFromXML(builder, parsed); } else if (XmlSureTyperParser.ROOT_ELEMENT.equals(rootElement)) { - builder.sourceType("SureTyper"); + builder.sourceType(SourceType.SureTyper); XmlSureTyperParser.buildModelFromXML(builder, parsed); } } else { diff --git a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java index 851f1c74..c18b9df6 100644 --- a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java @@ -5,23 +5,21 @@ import static org.junit.Assert.fail; import static org.junit.Assume.assumeNotNull; import static org.junit.Assume.assumeTrue; - import java.io.File; import java.util.ArrayList; import java.util.Collection; import java.util.List; import java.util.Objects; - import org.junit.Test; import org.junit.runner.RunWith; import org.junit.runners.Parameterized; import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; +import org.pankratzlab.unet.model.ValidationModelBuilder.ValidationResult; import org.pankratzlab.unet.model.ValidationTable; import org.pankratzlab.unet.parser.HtmlDonorParser; import org.pankratzlab.unet.parser.PdfDonorParser; import org.pankratzlab.unet.parser.XmlDonorParser; - import com.google.common.collect.ImmutableList; /** @@ -38,6 +36,7 @@ @RunWith(Parameterized.class) public class IntegrationTest { + private static final String REMAP_FILE = "remap.xml"; private static final String SURETYPER_PDF_FILE = "typer.pdf"; private static final String SCORE6_XML_FILE = "score6.xml"; private static final String DONORNET_XML_FILE = "donornet.xml"; @@ -111,7 +110,8 @@ private void testIfModelsAgree(List individualModels) { * return the results */ private List parseIndividualFiles(File individualDir) { - List models = new ArrayList<>(); + List modelBuilders = new ArrayList<>(); + XMLRemapProcessor remapProcessor = null; for (File individualFile : individualDir.listFiles()) { ValidationModelBuilder builder = new ValidationModelBuilder(); @@ -122,16 +122,37 @@ private List parseIndividualFiles(File individualDir) { new File(individualFile.getAbsolutePath() + File.separator + DONORNET_HTML_FILE); if (donorNetHtmlFile.exists()) { new HtmlDonorParser().parseModel(builder, donorNetHtmlFile); - models.add(builder.build()); } } else if (individualFileName.endsWith(DONORNET_XML_FILE) || individualFileName.endsWith(SCORE6_XML_FILE)) { new XmlDonorParser().parseModel(builder, individualFile); - models.add(builder.build()); } else if (individualFileName.endsWith(SURETYPER_PDF_FILE)) { new PdfDonorParser().parseModel(builder, individualFile); - models.add(builder.build()); + } else if (individualFileName.endsWith(REMAP_FILE)) { + // construct RemapProcessor from XML remap file + remapProcessor = new XMLRemapProcessor(individualFileName); + // no model to be built from this file, so continue; + continue; } + modelBuilders.add(builder); + } + + List models = new ArrayList<>(); + for (ValidationModelBuilder builder : modelBuilders) { + + if (builder.hasCorrections()) { + // assertion check if builder *should* have corrections + assertTrue(remapProcessor != null); + assertTrue(remapProcessor.hasRemappings(builder.getSourceType())); + + ValidationResult result = builder.processCorrections(remapProcessor); + assertTrue(result.valid); + assertFalse(result.validationMessage.isPresent()); + } else { + assertTrue(remapProcessor == null); + } + + models.add(builder.build()); } return models; diff --git a/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java new file mode 100644 index 00000000..c9c2d8b2 --- /dev/null +++ b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java @@ -0,0 +1,68 @@ +package org.pankratzlab.unet.integration; + +import java.io.File; +import java.io.FileInputStream; +import java.util.Set; +import org.apache.commons.lang3.tuple.Pair; +import org.jsoup.Jsoup; +import org.jsoup.nodes.Document; +import org.jsoup.nodes.Element; +import org.jsoup.select.Elements; +import org.pankratzlab.unet.deprecated.hla.HLALocus; +import org.pankratzlab.unet.deprecated.hla.HLAType; +import org.pankratzlab.unet.deprecated.hla.SourceType; +import org.pankratzlab.unet.model.ValidationModelBuilder; +import org.pankratzlab.unet.model.ValidationModelBuilder.TypePair; +import org.pankratzlab.unet.model.remap.CancellationException; +import org.pankratzlab.unet.model.remap.RemapProcessor; +import com.google.common.collect.HashBasedTable; +import com.google.common.collect.ImmutableSet; +import com.google.common.collect.Table; + +public class XMLRemapProcessor implements RemapProcessor { + + private Table, Set>> remappings = + HashBasedTable.create(); + + public XMLRemapProcessor(String file) { + try (FileInputStream xmlStream = new FileInputStream(new File(file))) { + Document parsed = Jsoup.parse(xmlStream, "UTF-8", "http://example.com"); + Elements remapElements = parsed.getElementsByTag("remappings"); + remapElements = remapElements.get(0).getElementsByTag("remap"); + remapElements.forEach(e -> { + e.getElementsByTag("remapLocus").forEach(locusElement -> { + // TODO catch missing or malformed SourceType values and report + SourceType source = + SourceType.valueOf(locusElement.getElementsByTag("sourceType").get(0).text()); + // TODO catch missing or malformed locus values and report + HLALocus locus = HLALocus.valueOf(locusElement.getElementsByTag("locus").get(0).text()); + HLAType[] fromAlleles = locusElement.getElementsByTag("fromAllele").stream() + .map(Element::text).map(HLAType::valueOf).toArray(HLAType[]::new); + HLAType[] toAlleles = locusElement.getElementsByTag("toAllele").stream() + .map(Element::text).map(HLAType::valueOf).toArray(HLAType[]::new); + // TODO catch missing or malformed allele values and report + remappings.put(source, locus, + Pair.of( + ImmutableSet.of(new TypePair(fromAlleles[0], fromAlleles[0].equivSafe()), + new TypePair(fromAlleles[1], fromAlleles[1].equivSafe())), + ImmutableSet.of(new TypePair(toAlleles[0], toAlleles[0].equivSafe()), + new TypePair(toAlleles[1], toAlleles[1].equivSafe())))); + + }); + }); + } catch (Throwable e) { + throw new IllegalStateException("Invalid XML file: " + file, e); + } + } + + @Override + public Pair, Set> processRemapping(HLALocus locus, + ValidationModelBuilder builder) throws CancellationException { + return remappings.get(builder.getSourceType(), locus); + } + + public boolean hasRemappings(SourceType sourceType) { + return remappings.containsRow(sourceType); + } + +} From d04fa615814495a0f07c06d2ace278463ab18a9d Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Fri, 7 Jun 2024 10:20:27 -0500 Subject: [PATCH 15/23] Fix integration test bugs; allow for no remappings --- .../unet/model/remap/RemapProcessor.java | 2 +- .../unet/integration/IntegrationTest.java | 34 +++++++++++++++---- .../unet/integration/XMLRemapProcessor.java | 31 +++++++++++++---- 3 files changed, 54 insertions(+), 13 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java b/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java index c3af1fc1..6cd4d7e1 100644 --- a/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java +++ b/src/main/java/org/pankratzlab/unet/model/remap/RemapProcessor.java @@ -11,4 +11,4 @@ public interface RemapProcessor { public Pair, Set> processRemapping(HLALocus locus, ValidationModelBuilder builder) throws CancellationException; -} \ No newline at end of file +} diff --git a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java index c18b9df6..1383ea60 100644 --- a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java @@ -10,13 +10,16 @@ import java.util.Collection; import java.util.List; import java.util.Objects; +import org.junit.Before; import org.junit.Test; import org.junit.runner.RunWith; import org.junit.runners.Parameterized; +import org.pankratzlab.unet.hapstats.CommonWellDocumented; import org.pankratzlab.unet.model.ValidationModel; import org.pankratzlab.unet.model.ValidationModelBuilder; import org.pankratzlab.unet.model.ValidationModelBuilder.ValidationResult; import org.pankratzlab.unet.model.ValidationTable; +import org.pankratzlab.unet.model.remap.RemapProcessor; import org.pankratzlab.unet.parser.HtmlDonorParser; import org.pankratzlab.unet.parser.PdfDonorParser; import org.pankratzlab.unet.parser.XmlDonorParser; @@ -49,6 +52,14 @@ public IntegrationTest(File individualDirectory) { individualDir = individualDirectory; } + @Before + public void setup() { + assumeTrue(Objects.nonNull(System.getProperty(TEST_DIR_PROPERTY))); + assumeTrue(Objects.nonNull(individualDir)); + + CommonWellDocumented.loadCIWD300(); + } + @Test public void validateInput() { assertTrue("Validation failed - no directory provided.", Objects.nonNull(individualDir)); @@ -81,7 +92,7 @@ public void integrationTest() { individualModels.size() == 1); testIfModelsAgree(individualModels); - } catch (Exception e) { + } catch (Throwable e) { e.printStackTrace(System.err); fail(individualName + ": failed with exception " + e.toString()); } @@ -123,6 +134,8 @@ private List parseIndividualFiles(File individualDir) { if (donorNetHtmlFile.exists()) { new HtmlDonorParser().parseModel(builder, donorNetHtmlFile); } + } else if (individualFileName.endsWith(DONORNET_HTML_FILE.toLowerCase())) { + new HtmlDonorParser().parseModel(builder, individualFile); } else if (individualFileName.endsWith(DONORNET_XML_FILE) || individualFileName.endsWith(SCORE6_XML_FILE)) { new XmlDonorParser().parseModel(builder, individualFile); @@ -130,9 +143,12 @@ private List parseIndividualFiles(File individualDir) { new PdfDonorParser().parseModel(builder, individualFile); } else if (individualFileName.endsWith(REMAP_FILE)) { // construct RemapProcessor from XML remap file - remapProcessor = new XMLRemapProcessor(individualFileName); + remapProcessor = new XMLRemapProcessor(individualFile.getAbsolutePath()); // no model to be built from this file, so continue; continue; + } else { + // skip any other files + continue; } modelBuilders.add(builder); } @@ -142,14 +158,20 @@ private List parseIndividualFiles(File individualDir) { if (builder.hasCorrections()) { // assertion check if builder *should* have corrections - assertTrue(remapProcessor != null); - assertTrue(remapProcessor.hasRemappings(builder.getSourceType())); + RemapProcessor remapper; + if (remapProcessor != null) { + assertTrue(remapProcessor.hasRemappings(builder.getSourceType())); + remapper = remapProcessor; + } else { + remapper = new XMLRemapProcessor.NoRemapProcessor(); + } - ValidationResult result = builder.processCorrections(remapProcessor); + ValidationResult result = builder.processCorrections(remapper); assertTrue(result.valid); assertFalse(result.validationMessage.isPresent()); } else { - assertTrue(remapProcessor == null); + assertTrue( + remapProcessor == null || !remapProcessor.hasRemappings(builder.getSourceType())); } models.add(builder.build()); diff --git a/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java index c9c2d8b2..69c8ad31 100644 --- a/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java +++ b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java @@ -21,6 +21,23 @@ public class XMLRemapProcessor implements RemapProcessor { + public static class NoRemapProcessor implements RemapProcessor { + @Override + public Pair, Set> processRemapping(HLALocus locus, + ValidationModelBuilder builder) throws CancellationException { + Set types = builder.getAllTypesForLocus(locus); + HLAType[] tp = types.toArray(new HLAType[types.size()]); + if (tp.length == 1) { + tp = new HLAType[] {tp[0], tp[0]}; + } + return Pair.of( + ImmutableSet.of(new TypePair(tp[0], tp[0].equivSafe()), + new TypePair(tp[1], tp[1].equivSafe())), + ImmutableSet.of(new TypePair(tp[0], tp[0].equivSafe()), + new TypePair(tp[1], tp[1].equivSafe()))); + } + } + private Table, Set>> remappings = HashBasedTable.create(); @@ -29,17 +46,19 @@ public XMLRemapProcessor(String file) { Document parsed = Jsoup.parse(xmlStream, "UTF-8", "http://example.com"); Elements remapElements = parsed.getElementsByTag("remappings"); remapElements = remapElements.get(0).getElementsByTag("remap"); + SourceType source = + SourceType.valueOf(remapElements.get(0).getElementsByTag("sourceType").get(0).text()); remapElements.forEach(e -> { e.getElementsByTag("remapLocus").forEach(locusElement -> { // TODO catch missing or malformed SourceType values and report - SourceType source = - SourceType.valueOf(locusElement.getElementsByTag("sourceType").get(0).text()); // TODO catch missing or malformed locus values and report HLALocus locus = HLALocus.valueOf(locusElement.getElementsByTag("locus").get(0).text()); - HLAType[] fromAlleles = locusElement.getElementsByTag("fromAllele").stream() - .map(Element::text).map(HLAType::valueOf).toArray(HLAType[]::new); - HLAType[] toAlleles = locusElement.getElementsByTag("toAllele").stream() - .map(Element::text).map(HLAType::valueOf).toArray(HLAType[]::new); + HLAType[] fromAlleles = + locusElement.getElementsByTag("fromAllele").stream().map(Element::text) + .map(s -> locus.name() + "*" + s).map(HLAType::valueOf).toArray(HLAType[]::new); + HLAType[] toAlleles = + locusElement.getElementsByTag("toAllele").stream().map(Element::text) + .map(s -> locus.name() + "*" + s).map(HLAType::valueOf).toArray(HLAType[]::new); // TODO catch missing or malformed allele values and report remappings.put(source, locus, Pair.of( From b373c7bf2e5154732b62dbc44fe0d0f88f9545cf Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:23:17 -0500 Subject: [PATCH 16/23] If no remaps in test, proceed with default assignments --- .../org/pankratzlab/unet/integration/IntegrationTest.java | 4 ++-- .../org/pankratzlab/unet/integration/XMLRemapProcessor.java | 5 +++++ 2 files changed, 7 insertions(+), 2 deletions(-) diff --git a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java index 1383ea60..ff2cd7f3 100644 --- a/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java +++ b/src/test/java/org/pankratzlab/unet/integration/IntegrationTest.java @@ -2,9 +2,9 @@ import static org.junit.Assert.assertFalse; import static org.junit.Assert.assertTrue; -import static org.junit.Assert.fail; import static org.junit.Assume.assumeNotNull; import static org.junit.Assume.assumeTrue; +import static org.junit.jupiter.api.Assertions.fail; import java.io.File; import java.util.ArrayList; import java.util.Collection; @@ -94,7 +94,7 @@ public void integrationTest() { testIfModelsAgree(individualModels); } catch (Throwable e) { e.printStackTrace(System.err); - fail(individualName + ": failed with exception " + e.toString()); + fail(individualName + ": failed with exception " + e.toString(), e); } } diff --git a/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java index 69c8ad31..1d0f79a4 100644 --- a/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java +++ b/src/test/java/org/pankratzlab/unet/integration/XMLRemapProcessor.java @@ -26,6 +26,11 @@ public static class NoRemapProcessor implements RemapProcessor { public Pair, Set> processRemapping(HLALocus locus, ValidationModelBuilder builder) throws CancellationException { Set types = builder.getAllTypesForLocus(locus); + if (types == null || types.size() == 0) { + // no types available for remapping, so return null to indicate locus should use + // default-assigned types + return null; + } HLAType[] tp = types.toArray(new HLAType[types.size()]); if (tp.length == 1) { tp = new HLAType[] {tp[0], tp[0]}; From 43453280894f4f8d14f4632e13a6505a43318e7d Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:23:44 -0500 Subject: [PATCH 17/23] Only consider unambiguous serology mapping --- .../deprecated/hla/AntigenDictionary.java | 19 +++++++++++-------- 1 file changed, 11 insertions(+), 8 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java index 8ef510b1..ccf24d3a 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/AntigenDictionary.java @@ -206,15 +206,18 @@ private static void parseDictionaries(Callable readerSupplier) { // Since the columns are ordered by specificity, we use the first column with valid entries // Set seroSpecs = new LinkedHashSet<>(); List seroSpecs = new ArrayList<>(); - for (int i = 2; i <= 5 && i < columns.length; i++) { - String types = columns[i]; - // Each HLA type may map to multiple serotypes - for (String t : types.split(TYPE_DELIM)) { - if (!t.isEmpty() && !seroSpecs.contains(t)) { - seroSpecs.add(t); - } - } + if (!columns[2].isEmpty()) { + seroSpecs.add(columns[2]); } + // for (int i = 2; i <= 5 && i < columns.length; i++) { + // String types = columns[i]; + // // Each HLA type may map to multiple serotypes + // for (String t : types.split(TYPE_DELIM)) { + // if (!t.isEmpty() && !seroSpecs.contains(t)) { + // seroSpecs.add(t); + // } + // } + // } // Skip null types if (seroSpecs.stream().anyMatch(NULL_TYPE::equals)) { From fc7702e8bd3ac5ba0f526db9bd1db73cbe759e16 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:24:17 -0500 Subject: [PATCH 18/23] If DR serotype is >2 characters, check if 2-char exists --- .../org/pankratzlab/unet/parser/util/DRAssociations.java | 6 +++++- 1 file changed, 5 insertions(+), 1 deletion(-) diff --git a/src/main/java/org/pankratzlab/unet/parser/util/DRAssociations.java b/src/main/java/org/pankratzlab/unet/parser/util/DRAssociations.java index 3e0b359c..325aa9f4 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/DRAssociations.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/DRAssociations.java @@ -25,7 +25,6 @@ import java.util.Optional; import org.pankratzlab.unet.deprecated.hla.HLALocus; import org.pankratzlab.unet.deprecated.hla.SeroType; - import com.google.common.collect.ImmutableMap; import com.google.common.collect.ImmutableMap.Builder; @@ -75,6 +74,11 @@ private static ImmutableMap drMap() { public static Optional getDRBLocus(SeroType drType) { if (Objects.nonNull(drType) && drMap().containsKey(drType)) { return Optional.of(drMap().get(drType)); + } else if (Objects.nonNull(drType) && drType.specString().length() > 2) { + SeroType subType = new SeroType(drType.locus(), drType.specString().substring(0, 2)); + if (drMap().containsKey(subType)) { + return Optional.of(drMap().get(subType)); + } } return Optional.ofNullable(null); } From 5e693deb52aaabe4514732dabc6fe70053f5fa0e Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:25:09 -0500 Subject: [PATCH 19/23] Fix CIWD weights so WD < I --- .../org/pankratzlab/unet/hapstats/CommonWellDocumented.java | 2 +- src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java | 1 - 2 files changed, 1 insertion(+), 2 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java b/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java index 9f64bacd..26004308 100644 --- a/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java +++ b/src/main/java/org/pankratzlab/unet/hapstats/CommonWellDocumented.java @@ -69,7 +69,7 @@ public final class CommonWellDocumented { CacheBuilder.newBuilder().build(CacheLoader.from(CommonWellDocumented::doGetStatus)); public static enum Status { - COMMON(1.0), INTERMEDIATE(0.5), WELL_DOCUMENTED(0.5), UNKNOWN(0.0); + COMMON(1.0), INTERMEDIATE(0.5), WELL_DOCUMENTED(0.25), UNKNOWN(0.0); private final double weight; diff --git a/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java b/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java index e0786a85..c06d0d53 100644 --- a/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java +++ b/src/main/java/org/pankratzlab/unet/model/DRDQHaplotypeRow.java @@ -61,7 +61,6 @@ public DRDQHaplotypeRow(RaceGroup ethnicity, Haplotype haplotype) { break; } } - // TODO split into separate throws indicating which is missing if (Objects.isNull(dqb1)) { throw new IllegalArgumentException( "Invalid DRB345-DRB1-DQB1 haplotype, missing DQB1: " + haplotype.toShortString()); From 06f89e8f8885a8b92154966fec0c06c32091310a Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:26:06 -0500 Subject: [PATCH 20/23] Handle null objects differently in CareDX sero-map parsing --- .../unet/parser/util/SerotypeEquivalence.java | 16 +++++++++++++--- 1 file changed, 13 insertions(+), 3 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java index cc1dfcf7..a0056735 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/SerotypeEquivalence.java @@ -43,7 +43,7 @@ public final class SerotypeEquivalence { private static final ImmutableMap manualEquivalencies; private static final Set INVALID = - Sets.newHashSet(null, "-", "Undefined", "Null", "NotExpressed", "Blank"); + Sets.newHashSet("-", "Undefined", "Null", "NotExpressed", "Blank"); static { careDxEquivalencies = buildLookupFromCareDxXMLFile(); @@ -93,7 +93,12 @@ private static ImmutableMap buildLookupFromCareDxXMLFile() { Elements elementsByTag = parsed.getElementsByTag("allele"); for (Element e : elementsByTag) { - processAllele(builder, e); + try { + processAllele(builder, e); + } catch (NullPointerException e1) { + System.err.println("Couldn't find allele name: " + e.toString()); + continue; + } } } catch (IOException e) { @@ -119,8 +124,13 @@ private static void processAllele(Builder builder, Element e) String careDxSeroText = expertElements.isEmpty() ? null : expertElements.get(0).text(); Elements whoElements = e.getElementsByTag("WHO"); String whoSeroText = whoElements.isEmpty() ? null : whoElements.get(0).text(); - if (INVALID.contains(careDxSeroText) && INVALID.contains(whoSeroText)) + boolean inval1 = careDxSeroText == null || INVALID.stream().map(String::toLowerCase) + .filter(s -> careDxSeroText.toLowerCase().contains(s)).count() > 0; + boolean inval2 = whoSeroText == null || INVALID.stream().map(String::toLowerCase) + .filter(s -> whoSeroText.toLowerCase().contains(s)).count() > 0; + if (inval1 && inval2) { return; + } try { HLALocus locus = HLALocus.valueOf("" + careDxSeroText.charAt(0)); From 380438108cc473c7d15428f928d8457ede699f57 Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:27:32 -0500 Subject: [PATCH 21/23] Change object/variable names to better reflect subject defs --- .../unet/deprecated/hla/HLALocus.java | 8 +- .../unet/deprecated/hla/Locus.java | 4 +- .../unet/deprecated/hla/SeroLocus.java | 4 +- .../unet/model/ValidationModelBuilder.java | 87 +++++++++++-------- 4 files changed, 61 insertions(+), 42 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/HLALocus.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/HLALocus.java index ebc158ef..e30da2b3 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/HLALocus.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/HLALocus.java @@ -25,10 +25,10 @@ /** {@link Locus} implementation for HLA types */ public enum HLALocus implements Locus { - A(SeroLocus.A, TIER_1), B(SeroLocus.B, TIER_1), C(SeroLocus.C, TIER_1), DRB1(SeroLocus.DRB, - TIER_2), DRB3(SeroLocus.DRB, TIER_2), DRB4(SeroLocus.DRB, TIER_2), DRB5(SeroLocus.DRB, - TIER_2), DQA1(SeroLocus.DQA, TIER_2), DQB1(SeroLocus.DQB, TIER_2), DPA1(SeroLocus.DPA, - TIER_2), DPB1(SeroLocus.DPB, TIER_2), MICA(SeroLocus.MICA, TIER_2); + A(SeroLocus.A, MHC_CLASS_1), B(SeroLocus.B, MHC_CLASS_1), C(SeroLocus.C, MHC_CLASS_1), DRB1(SeroLocus.DRB, + MHC_CLASS_2), DRB3(SeroLocus.DRB, MHC_CLASS_2), DRB4(SeroLocus.DRB, MHC_CLASS_2), DRB5(SeroLocus.DRB, + MHC_CLASS_2), DQA1(SeroLocus.DQA, MHC_CLASS_2), DQB1(SeroLocus.DQB, MHC_CLASS_2), DPA1(SeroLocus.DPA, + MHC_CLASS_2), DPB1(SeroLocus.DPB, MHC_CLASS_2), MICA(SeroLocus.MICA, MHC_CLASS_2); private final SeroLocus sero; private final int tier; diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/Locus.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/Locus.java index 262bb845..b8674eb2 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/Locus.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/Locus.java @@ -23,8 +23,8 @@ /** Marker interface for antigen loci */ public interface Locus extends Comparable { - public static int TIER_1 = 1; - public static int TIER_2 = 2; + public static int MHC_CLASS_1 = 1; + public static int MHC_CLASS_2 = 2; /** @return Name of this locus */ String name(); diff --git a/src/main/java/org/pankratzlab/unet/deprecated/hla/SeroLocus.java b/src/main/java/org/pankratzlab/unet/deprecated/hla/SeroLocus.java index c3eabec6..92c6b1a6 100644 --- a/src/main/java/org/pankratzlab/unet/deprecated/hla/SeroLocus.java +++ b/src/main/java/org/pankratzlab/unet/deprecated/hla/SeroLocus.java @@ -29,8 +29,8 @@ /** {@link Locus} implementation for serological types */ public enum SeroLocus implements Locus { - A(2, TIER_1), B(2, TIER_1), C(3, TIER_1), DRB(1, TIER_2, "DR"), DQB(1, TIER_2, "DQ"), DQA(1, - TIER_2), DPB(1, TIER_2, "DP"), DPA(1, TIER_2), MICA(1, -1); + A(2, MHC_CLASS_1), B(2, MHC_CLASS_1), C(3, MHC_CLASS_1), DRB(1, MHC_CLASS_2, "DR"), DQB(1, MHC_CLASS_2, "DQ"), DQA(1, + MHC_CLASS_2), DPB(1, MHC_CLASS_2, "DP"), DPA(1, MHC_CLASS_2), MICA(1, -1); private final int severity; private final int tier; diff --git a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java index e2d7f281..a84d4d49 100644 --- a/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java +++ b/src/main/java/org/pankratzlab/unet/model/ValidationModelBuilder.java @@ -127,27 +127,26 @@ public class ValidationModelBuilder { private Map, Set>> remapping = new HashMap<>(); private Set drbLocus; - // private Set drbLocusTypes; private Set drbLocusNonCWD; private Set dqaLocus; - private Set dqaLocusTypes; - private Set dqaLocusTypesNonCWD; private Set dqaLocusNonCWD; + private Set dqaLocusAlleles; + private Set dqaLocusAllelesNonCWD; private Set dqbLocus; - private Set dqbLocusTypes; - private Set dqbLocusTypesNonCWD; private Set dqbLocusNonCWD; + private Set dqbLocusAlleles; + private Set dqbLocusAllelesNonCWD; private Set dpaLocus; - private Set dpaLocusTypes; - private Set dpaLocusTypesNonCWD; private Set dpaLocusNonCWD; + private Set dpaLocusAlleles; + private Set dpaLocusAllelesNonCWD; private Set dpbLocus; - private Set dpbLocusTypes; - private Set dpbLocusTypesNonCWD; + private Set dpbLocusAlleles; + private Set dpbLocusAllelesNonCWD; private Set dpbLocusNonCWD; private Boolean bw4; @@ -319,6 +318,13 @@ public ValidationModelBuilder drbNonCWD(String drbType) { return this; } + /** + * DR51 is a HLA-DR serotype that recognizes the antigens encoded by the minor DR locus HLA-DRB5 + * (cc wikipedia) + * + * @param dr51 + * @return + */ public ValidationModelBuilder dr51(String dr51) { if (isPositive(dr51)) { dr51Locus.add(new HLAType(HLALocus.DRB5, dr51)); @@ -326,6 +332,12 @@ public ValidationModelBuilder dr51(String dr51) { return this; } + /** + * DR52 is an HLA-DR serotype that recognizes gene products of HLA-DRB3 locus (cc wikipedia) + * + * @param dr52 + * @return + */ public ValidationModelBuilder dr52(String dr52) { if (isPositive(dr52)) { dr52Locus.add(new HLAType(HLALocus.DRB3, dr52)); @@ -333,6 +345,12 @@ public ValidationModelBuilder dr52(String dr52) { return this; } + /** + * DR53 is an HLA-DR serotype that recognizes gene products of HLA-DRB4 (cc wikipedia) + * + * @param dr53 + * @return + */ public ValidationModelBuilder dr53(String dr53) { if (isPositive(dr53)) { dr53Locus.add(new HLAType(HLALocus.DRB4, dr53)); @@ -411,8 +429,8 @@ public ValidationModelBuilder dpaSerotype(String dpaType) { } public ValidationModelBuilder dpb(HLAType dpbType) { - dpbLocusTypes = makeIfNull(dpbLocusTypes); - dpbLocusTypes.add(dpbType); + dpbLocusAlleles = makeIfNull(dpbLocusAlleles); + dpbLocusAlleles.add(dpbType); return this; } @@ -425,8 +443,8 @@ public ValidationModelBuilder dpbSerotype(String dpbType) { } public ValidationModelBuilder dpbNonCIWD(HLAType dpbType) { - dpbLocusTypesNonCWD = makeIfNull(dpbLocusTypesNonCWD); - dpbLocusTypesNonCWD.add(dpbType); + dpbLocusAllelesNonCWD = makeIfNull(dpbLocusAllelesNonCWD); + dpbLocusAllelesNonCWD.add(dpbType); return this; } @@ -434,8 +452,8 @@ public ValidationModelBuilder dqbType(HLAType dqbType) { if (test2(dqbType)) { return null; } - dqbLocusTypes = makeIfNull(dqbLocusTypes); - addToLocus(dqbLocusTypes, HLALocus.DQB1, dqbType); + dqbLocusAlleles = makeIfNull(dqbLocusAlleles); + addToLocus(dqbLocusAlleles, HLALocus.DQB1, dqbType); return this; } @@ -443,8 +461,8 @@ public ValidationModelBuilder dqbTypeNonCWD(HLAType dqbType) { if (test2(dqbType)) { return null; } - dqbLocusTypesNonCWD = makeIfNull(dqbLocusTypesNonCWD); - addToLocus(dqbLocusTypesNonCWD, HLALocus.DQB1, dqbType); + dqbLocusAllelesNonCWD = makeIfNull(dqbLocusAllelesNonCWD); + addToLocus(dqbLocusAllelesNonCWD, HLALocus.DQB1, dqbType); return this; } @@ -452,8 +470,8 @@ public ValidationModelBuilder dqaType(HLAType dqaType) { if (test2(dqaType)) { return null; } - dqaLocusTypes = makeIfNull(dqaLocusTypes); - addToLocus(dqaLocusTypes, HLALocus.DQA1, dqaType); + dqaLocusAlleles = makeIfNull(dqaLocusAlleles); + addToLocus(dqaLocusAlleles, HLALocus.DQA1, dqaType); return this; } @@ -461,8 +479,8 @@ public ValidationModelBuilder dqaTypeNonCWD(HLAType dqaType) { if (test2(dqaType)) { return null; } - dqaLocusTypesNonCWD = makeIfNull(dqaLocusTypesNonCWD); - addToLocus(dqaLocusTypesNonCWD, HLALocus.DQA1, dqaType); + dqaLocusAllelesNonCWD = makeIfNull(dqaLocusAllelesNonCWD); + addToLocus(dqaLocusAllelesNonCWD, HLALocus.DQA1, dqaType); return this; } @@ -470,8 +488,8 @@ public ValidationModelBuilder dpaType(HLAType dpaType) { if (test2(dpaType)) { return null; } - dpaLocusTypes = makeIfNull(dpaLocusTypes); - addToLocus(dpaLocusTypes, HLALocus.DPA1, dpaType); + dpaLocusAlleles = makeIfNull(dpaLocusAlleles); + addToLocus(dpaLocusAlleles, HLALocus.DPA1, dpaType); return this; } @@ -479,8 +497,8 @@ public ValidationModelBuilder dpaTypeNonCWD(HLAType dpaType) { if (test2(dpaType)) { return null; } - dpaLocusTypesNonCWD = makeIfNull(dpaLocusTypesNonCWD); - addToLocus(dpaLocusTypesNonCWD, HLALocus.DPA1, dpaType); + dpaLocusAllelesNonCWD = makeIfNull(dpaLocusAllelesNonCWD); + addToLocus(dpaLocusAllelesNonCWD, HLALocus.DPA1, dpaType); return this; } @@ -655,7 +673,7 @@ private Set getFinalDPBTypes() { if (!returnTypes.isEmpty()) { dpbSource.addAll(returnTypes); } else { - dpbSource = test1(dpbLocusTypesNonCWD) ? dpbLocusTypes : dpbLocusTypesNonCWD; + dpbSource = test1(dpbLocusAllelesNonCWD) ? dpbLocusAlleles : dpbLocusAllelesNonCWD; Set dpbBackup = test1(dpbLocusNonCWD) ? dpbLocus : trim(dpbLocusNonCWD); if (dpbSource == null || dpbSource.isEmpty()) { dpbSource = dpbBackup.stream().map(s -> new HLAType(HLALocus.DPB1, s.spec())) @@ -1157,13 +1175,13 @@ public Set getCWDTypesForLocus(HLALocus locus) { case C: return cLocusCWDTypes; case DPA1: - return dpaLocusTypes; + return dpaLocusAlleles; case DQA1: - return dqaLocusTypes; + return dqaLocusAlleles; case DPB1: - return dpbLocusTypes; + return dpbLocusAlleles; case DQB1: - return dqbLocusTypes; + return dqbLocusAlleles; case DRB1: case DRB3: case DRB4: @@ -1183,17 +1201,18 @@ public Set getAllTypesForLocus(HLALocus locus) { case C: return cLocusFirstTypes; case DPA1: - return dpaLocusTypesNonCWD; + return dpaLocusAllelesNonCWD; case DQA1: - return dqaLocusTypesNonCWD; + return dqaLocusAllelesNonCWD; case DPB1: - return dpbLocusTypesNonCWD; + return dpbLocusAllelesNonCWD; case DQB1: - return dqbLocusTypesNonCWD; + return dqbLocusAllelesNonCWD; case DRB1: case DRB3: case DRB4: case DRB5: + case MICA: default: return null; } From 32d3b797910786a9dba16c297b97107a42a27eeb Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:33:26 -0500 Subject: [PATCH 22/23] Score6 XML parsing updates * Properly parse groups if the group starts with a non-regular allele * Properly parse "first" allele (vs CIWD) - undefined/null allowed as first * Parse serotypes differently than alleles * Fix 'locusIsNonCIWD' check - only set as true if either of first alleles is Unknown *AND* the two-field version of the first alleles don't match the two-field version of the chosen CIWD pair. * Fix DRB parsing (previously slightly broken due to first vs CIWD parsing) * Track DRB alleles for remappings --- .../unet/parser/util/XmlScore6Parser.java | 200 +++++++++++++----- 1 file changed, 149 insertions(+), 51 deletions(-) diff --git a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java index 1168d35b..5a60bf1c 100644 --- a/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java +++ b/src/main/java/org/pankratzlab/unet/parser/util/XmlScore6Parser.java @@ -208,6 +208,7 @@ private static void init() { setterBuilderAlleles.put(DQB_HEADER, ValidationModelBuilder::possibleAllelePairings); setterBuilderAlleles.put(DPA_HEADER, ValidationModelBuilder::possibleAllelePairings); setterBuilderAlleles.put(DPB_HEADER, ValidationModelBuilder::possibleAllelePairings); + setterBuilderAlleles.put(DRB_HEADER, ValidationModelBuilder::possibleAllelePairings); possibleAlleleRecordingMap = setterBuilderAlleles.build(); @@ -220,6 +221,7 @@ private static void init() { setterBuilderDonorAlleles.put(DQB_HEADER, ValidationModelBuilder::donorAllelePairings); setterBuilderDonorAlleles.put(DPA_HEADER, ValidationModelBuilder::donorAllelePairings); setterBuilderDonorAlleles.put(DPB_HEADER, ValidationModelBuilder::donorAllelePairings); + setterBuilderDonorAlleles.put(DRB_HEADER, ValidationModelBuilder::donorAllelePairings); donorAlleleRecordingMap = setterBuilderDonorAlleles.build(); @@ -280,6 +282,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo Elements resultCombinations = typedLocus.getElementsByTag(ALLELE_RESULTS_TAG).get(0) .getElementsByTag(RESULT_COMBINATION_TAG); + // each locus has one allele combination block which contains possible allele pairs Elements alleleCombinations = typedLocus.getElementsByTag(ALLELE_COMBINATIONS_TAG).get(0) .getElementsByTag(RESULT_COMBINATION_TAG); @@ -290,14 +293,16 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo int selectedResultIndex = -1; int selectedDRB345Index = -1; List firstResultPairs = new ArrayList<>(); - List actualResultPairs = new ArrayList<>(); + List ciwdResultPairs = new ArrayList<>(); List drb345Pairs = new ArrayList<>(); + List drb345PairsFirst = new ArrayList<>(); HLALocus hlaLocus = null; AllelePairings allPossibleAllelePairs = new AllelePairings(); AllelePairings donorAllelePairs = new AllelePairings(); + // first, iterate through allele list element pairs and parse possible allele pairings for (int i = 0; i < pairs.size(); i++) { Element currPair = pairs.get(i); Elements a1Alleles = @@ -314,6 +319,17 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo } } + // next, parse alleleCombinations elements for donor's possible allele pairs + // these are different from the alleleResults elements + /* + * Class-1 Loci (A/B/C) have one set of possible allele pairs in the alleleResults element + * + * Class-2 Loci (DR/DP/DQ) can have multiple sets of possible allele pairs in the + * alleleResults element + * + * TODO clarify how/why these are different + */ + for (int currentResult = 0; currentResult < alleleCombinations.size(); currentResult++) { Element currentCombination = alleleCombinations.get(currentResult); HLALocus locusType = null; @@ -330,7 +346,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo // unexpressed DRB345s // In this scenario, we can fall back to looking at the DRB1 alleles to figure out what // we should find. - locusType = deduceDRB345Locus(actualResultPairs); + locusType = deduceDRB345Locus(ciwdResultPairs); } } else { locusType = HLALocus.safeValueOf(locus.substring(locus.indexOf("-") + 1)); @@ -340,7 +356,15 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo parseAlleleCombinations(currentCombination, locusType, donorAllelePairs); } - // Parse the allele pairs in the result section + // Parse the allele lists in the result section + // the first allele in each list goes into the "firstResultPairs" list + // the first **CIWD allele** goes into the "actualResultPairs" list + + /* + * if we're parsing a Class-2 locus, we find the "best" pair to use for the + * "actualResultPairs" list, and then use the first pairing from that pair for the + * "firstResultPairs" list + */ for (int currentResult = 0; currentResult < resultCombinations.size(); currentResult++) { Element currentCombination = resultCombinations.get(currentResult); HLALocus locusType = null; @@ -357,7 +381,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo // unexpressed DRB345s // In this scenario, we can fall back to looking at the DRB1 alleles to figure out what // we should find. - locusType = deduceDRB345Locus(actualResultPairs); + locusType = deduceDRB345Locus(ciwdResultPairs); } } else { locusType = HLALocus.safeValueOf(locus.substring(locus.indexOf("-") + 1)); @@ -366,40 +390,46 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo if (hlaLocus == null) { hlaLocus = locusType; } else if (hlaLocus.compareTo(locusType) != 0) { - // TODO FIXME do something other than print to system out - System.out - .println("Parsed different locus (prev / new): " + hlaLocus + " / " + locusType); + /* + * This seems to only happen when parsing the DRB3/4/5 loci, as the original locus is DRB1 + */ } // Each combination is an allele/antigen pair - List combinations = + List comboCIWD = parseResultCombinations(currentCombination, locusType, true); - List combinations1 = + List comboFirst = parseResultCombinations(currentCombination, locusType, false); - List toUpdate = actualResultPairs; + List toUpdateCIWD = ciwdResultPairs; List toUpdateFirst = firstResultPairs; if (isDRB345) { - toUpdate = drb345Pairs; + toUpdateCIWD = drb345Pairs; + toUpdateFirst = drb345PairsFirst; // Ensure we only check DRB345 combinations that are consistent with the DRB1 result - Multiset countDRB1 = countDRB1(actualResultPairs); - Multiset countDRB345 = countDRB345(combinations); + Multiset countDRB1 = countDRB1(ciwdResultPairs); + Multiset countDRB345 = countDRB345(comboCIWD); if (countDRB345.size() > countDRB1.size() || !countDRB1.containsAll(countDRB345)) { continue; } } // Check if the current combination is better than the last best combination - if (!toUpdate.isEmpty() && isTestListPreferred(toUpdate, combinations)) { - toUpdate.clear(); + if (!toUpdateCIWD.isEmpty() && isTestListPreferred(toUpdateCIWD, comboCIWD)) { + // if so, clear both CIWD/First lists + toUpdateCIWD.clear(); + toUpdateFirst.clear(); } - if (toUpdate.isEmpty()) { + if (toUpdateCIWD.isEmpty()) { // Record this set - toUpdate.addAll(combinations); - toUpdateFirst.addAll(combinations1); + toUpdateCIWD.addAll(comboCIWD); + if (!toUpdateFirst.isEmpty()) { + toUpdateFirst.clear(); + } + toUpdateFirst.addAll(comboFirst); if (!isDRB345) { // The selected result is the selected non-DRB345 index @@ -411,9 +441,9 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo } // -- Locus-specific processing of the individual types -- - if (!Objects.isNull(drb345Pairs) && !drb345Pairs.isEmpty()) { + if (!Objects.isNull(drb345PairsFirst) && !drb345PairsFirst.isEmpty()) { // Set the DRB345 types - for (ResultCombination drbType : drb345Pairs) { + for (ResultCombination drbType : drb345PairsFirst) { HLAType drbAllele = drbType.getAlleleCombination(); if (drbMap.containsKey(drbAllele.locus())) { String drbString = String.valueOf(drbAllele.spec().get(0)); @@ -434,7 +464,7 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo identityLocusMap(HLALocus.DRB1), ValidationModelBuilder::drHaplotype); if (selectedDRB345Index > 0) { addHaplotypes(builder, resultCombinations.get(selectedDRB345Index), - drb345Map(actualResultPairs), ValidationModelBuilder::dr345Haplotype); + drb345Map(ciwdResultPairs), ValidationModelBuilder::dr345Haplotype); } else { builder.dr345Haplotype(ArrayListMultimap.create()); } @@ -442,15 +472,15 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo addHaplotypes(builder, resultCombinations.get(selectedResultIndex), identityLocusMap(HLALocus.B), ValidationModelBuilder::bHaplotype); - for (int strandIdx = 0; strandIdx < actualResultPairs.size(); strandIdx++) { + for (int strandIdx = 0; strandIdx < ciwdResultPairs.size(); strandIdx++) { // B*47:03 is considered BW6 despite B47 antigen being considered BW4 - if (actualResultPairs.get(strandIdx).alleleCombination.toString().contains("B*47:03")) { + if (ciwdResultPairs.get(strandIdx).alleleCombination.toString().contains("B*47:03")) { builder.bw6(true); break; } // Update the appropriate builder flags BwGroup bw = - BwSerotypes.getBwGroup(actualResultPairs.get(strandIdx).getAntigenCombination()); + BwSerotypes.getBwGroup(ciwdResultPairs.get(strandIdx).getAntigenCombination()); switch (bw) { case Bw4: builder.bw4(true); @@ -468,18 +498,45 @@ private static void processLocus(ValidationModelBuilder builder, Element typedLo } // Finally, add the types to the model builder - for (int i = 0; i < actualResultPairs.size(); i++) { - final HLAType alleleCombination = actualResultPairs.get(i).alleleCombination; - final HLAType alleleCombination2 = firstResultPairs.get(i).alleleCombination; - if (alleleCombination.compareTo(alleleCombination2) != 0) { - Status sA = CommonWellDocumented.getStatus(alleleCombination); - Status sF = CommonWellDocumented.getStatus(alleleCombination2); - if (sA == Status.UNKNOWN || sF == Status.UNKNOWN) { - builder.locusIsNonCIWD(alleleCombination); - } + // if the first two fields of the firstResultPairs alleles are the same + // as the first two fields of the actualResultPairs alleles, we don't + // need to flag this locus as non-CIWD + Set ciwdTwoField = new HashSet<>(); + Set firstTwoField = new HashSet<>(); + + for (int i = 0; i < ciwdResultPairs.size(); i++) { + HLAType ciwdAllele = ciwdResultPairs.get(i).alleleCombination; + if (ciwdAllele.resolution() > 2) { + ciwdAllele = + new HLAType(ciwdAllele.locus(), ciwdAllele.spec().get(0), ciwdAllele.spec().get(1)); + } else if (ciwdAllele.resolution() == 1) { + // TODO } + ciwdTwoField.add(ciwdAllele); + } - String specStringActual = specStringGeneratorMap.get(locus).apply(actualResultPairs.get(i)); + for (int i = 0; i < firstResultPairs.size(); i++) { + HLAType firstAllele = firstResultPairs.get(i).alleleCombination; + if (firstAllele.resolution() > 2) { + firstAllele = new HLAType(firstAllele.locus(), firstAllele.spec().get(0), + firstAllele.spec().get(1)); + } else if (firstAllele.resolution() == 1) { + // TODO + } + firstTwoField.add(firstAllele); + } + + boolean hasUnknown = firstResultPairs.stream().map(ResultCombination::getAlleleCombination) + .map(CommonWellDocumented::getStatus).filter(c -> c == Status.UNKNOWN).count() > 0; + if (hasUnknown && !ciwdTwoField.containsAll(firstTwoField)) { + builder.locusIsNonCIWD(ciwdResultPairs.get(0).alleleCombination); + } + + for (int i = 0; i < ciwdResultPairs.size(); i++) { + final HLAType alleleCombination = ciwdResultPairs.get(i).alleleCombination; + final HLAType alleleCombination2 = firstResultPairs.get(i).alleleCombination; + + String specStringActual = specStringGeneratorMap.get(locus).apply(ciwdResultPairs.get(i)); String specStringFirst = specStringGeneratorMap.get(locus).apply(firstResultPairs.get(i)); metadataMap.get(locus).accept(builder, specStringActual); @@ -633,8 +690,10 @@ private static ResultCombination parseCombination(Element resultCombinations, String alleleString = typeFunction .apply(resultCombinations.getElementsByTag(alleleComboTag + combinationIndex), locus); - String antigenString = typeFunction + String antigenString1 = typeFunction .apply(resultCombinations.getElementsByTag(SERO_COMBINATION_TAG + combinationIndex), null); + String antigenString = + parseSerotype(resultCombinations.getElementsByTag(SERO_COMBINATION_TAG + combinationIndex)); if (!hasCombination(resultCombinations, combinationIndex, alleleComboTag) && !DISREGARD_SERO.contains(locus.toString())) { @@ -648,7 +707,7 @@ private static ResultCombination parseCombination(Element resultCombinations, if (alleleString != null) { - // Ensure this is a recognized alleles + // Ensure this is a recognized allele try { allele = HLAType.valueOf(alleleString); // This type is valid @@ -673,6 +732,36 @@ private static ResultCombination parseCombination(Element resultCombinations, return null; } + private static String parseSerotype(Elements results) { + String typeText = null; + if (!results.isEmpty() && results.get(0).hasText()) { + String type = null; + String[] resultTypes = results.get(0).text().replaceAll("\\s+", "").split(RESULT_SEPARATOR); + + for (int result = + 0; (Strings.isNullOrEmpty(type) || UNDEFINED_TOKENS.contains(type) || isNullType(type)) + && result < resultTypes.length; result++) { + String tmp = resultTypes[result]; + if (tmp.isEmpty()) { + // Sometimes a leading comma can create empty strings - skip these + continue; + } + if (isNullType(tmp) && Objects.nonNull(type)) { + // Null type overrides undefined, but not other types + continue; + } else if (UNDEFINED_TOKENS.contains(tmp) && Objects.nonNull(type) && !isNullType(type)) { + // Undefined type overrides null, but not any other type + continue; + } + if (Objects.nonNull(tmp)) { + type = tmp; + } + } + typeText = type; + } + return typeText; + } + /** * Read all possible alleles in a result combination. These will be used to compute the most * probable haplotypes. @@ -858,30 +947,34 @@ private static String getFirstValidType(Elements results, HLALocus locus) { String type = null; String[] resultTypes = results.get(0).text().replaceAll("\\s+", "").split(RESULT_SEPARATOR); - for (int result = - 0; (Strings.isNullOrEmpty(type) || UNDEFINED_TYPE.equals(type) || isNullType(type)) - && result < resultTypes.length; result++) { + for (int result = 0; (Strings.isNullOrEmpty(type)) && result < resultTypes.length; result++) { String tmp = resultTypes[result]; if (tmp.isEmpty()) { // Sometimes a leading comma can create empty strings - skip these continue; } - // Null and Undefined types don't take precedence over any other values - if (isNullType(tmp) && Objects.nonNull(type)) { - // Null type overrides undefined, but not other types - continue; - } else if (UNDEFINED_TOKENS.contains(tmp) && Objects.nonNull(type) && !isNullType(type)) { - // Undefined type overrides null, but not any other type - continue; - } else if (tmp.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE)) { - // This is an allele which is unlikely to be expressed, per - // http://hla.alleles.org/nomenclature/naming.html - continue; + int sep = -1; + if ((sep = tmp.indexOf("-")) != -1) { + tmp = tmp.substring(0, sep); } + + // // Null and Undefined types don't take precedence over any other values + // if (isNullType(tmp) && Objects.nonNull(type)) { + // // Null type overrides undefined, but not other types + // continue; + // } else if (UNDEFINED_TOKENS.contains(tmp) && Objects.nonNull(type) && !isNullType(type)) + // { + // // Undefined type overrides null, but not any other type + // continue; + // } else if (tmp.matches(ValidationModelBuilder.NOT_ON_CELL_SURFACE)) { + // // This is an allele which is unlikely to be expressed, per + // // http://hla.alleles.org/nomenclature/naming.html + // continue; + // } if (Objects.nonNull(tmp)) { // Sometimes the inheritance structure of the types is listed. We only want the first - // (most specific) type, with the best CWD status + // (most specific) type. if (tmp.contains(PARENT_TYPE_SEPARATOR)) { tmp = tmp.substring(0, tmp.indexOf(PARENT_TYPE_SEPARATOR)); } @@ -919,6 +1012,11 @@ private static String getFirstValidCWDType(Elements results, HLALocus locus) { continue; } + int sep = -1; + if ((sep = tmp.indexOf("-")) != -1) { + tmp = tmp.substring(0, sep); + } + // Null and Undefined types don't take precedence over any other values if (isNullType(tmp) && Objects.nonNull(type)) { // Null type overrides undefined, but not other types From 2cc8e411906d3550b69b063541e725cc71d2fa4d Mon Sep 17 00:00:00 2001 From: Ben Cole Date: Mon, 17 Jun 2024 14:35:10 -0500 Subject: [PATCH 23/23] Update version to 0.1.15 --- pom.xml | 2 +- src/main/resources/project.properties | 2 +- 2 files changed, 2 insertions(+), 2 deletions(-) diff --git a/pom.xml b/pom.xml index 51214572..d8940f8a 100644 --- a/pom.xml +++ b/pom.xml @@ -8,7 +8,7 @@ org.pankratzlab donor-check - 0.0.14 + 0.1.15 jar A stand-alone tool for validating DonorNet typing entries. diff --git a/src/main/resources/project.properties b/src/main/resources/project.properties index 2f08e7fb..36f345ba 100644 --- a/src/main/resources/project.properties +++ b/src/main/resources/project.properties @@ -1 +1 @@ -version = 0.0.14 \ No newline at end of file +version = 0.1.15 \ No newline at end of file