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TheAIR is a collection of immunoglobulin (Ig) clonotypes across 53 tissues from 544 individuals. CDR3 sequences were assembled from by ImReP from 8555 RNA-Seq samples. Data was collected and prepared by Genotype-Tissue Expression (GTEx v6) project. TheAIR has one of the largest collection of CDR3 sequences (n=3.6 million) and tissue types (n=53).
distinct clonotypes by the total number of raw RNA-Seq reads, which we call number of clonotypes per one million raw RNA-Seq reads (CPM).
Mangul, Serghei, et al. "Profiling adaptive immune repertoires across multiple human tissues by RNA Sequencing" bioRxiv (2016): 089235.
Slides from my talk at ISMB 2017 (HiTSeq 2017) are available here
TheAIR was prepared by Serghei Mangul. Please do not hesitate to contact me (smangul@ucla.edu) if you have any comments, suggestions, or clarification requests regarding the tutorial or if you would like to contribute to this resource.